© The Author 2016. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved.Cell walls of grasses, including cereal crops and biofuel grasses, comprise the majority of plant biomass and intimately influence plant growth, development and physiology. However, the functions of many cell wall synthesis genes, and the relationships among and the functions of cell wall components remain obscure. To better understand the patterns of cell wall accumulation and identify genes that act in grass (...) cell wall biosynthesis, we characterized 30 samples from aerial organs of rice at 10 developmental time points, 3-100 d post-germination. Within these samples, we measured 15 cell wall chemical components, enzymatic digestibility and 18 cell wall polysaccharide epitopes/ligands. We also used quantitative reverse transcription-PCR to measure expression of 50 glycosyltransferases, 15 acyltransferases and eight phenylpropanoid genes, many of which had previously been identified as being highly expressed in rice. Most cell wall components vary significantly during development, and correlations among them support current understanding of cell walls. We identified 92 significant correlations between cell wall components and gene expression and establish nine strong hypotheses for genes that synthesize xylans, mixed linkage glucan and pectin components. This work provides an extensive analysis of cell wall composition throughout rice development, identifies genes likely to synthesize grass cell walls, and provides a framework for development of genetically improved grasses for use in lignocellulosic biofuel production and agriculture. (shrink)

All major western countries today contain groups that differ in their religious beliefs, customary practices or ideas about the right way in which to live. How should public policy respond to this diversity? In this important new work, Brian Barry challenges the currently orthodox answer and develops a powerful restatement of an egalitarian liberalism for the twenty-first century. Until recently it was assumed without much question that cultural diversity could best be accommodated by leaving cultural minorities free to associate (...) in pursuit of their distinctive ends within the limits imposed by a common framework of laws. This solution is rejected by an influential school of political theorists, among whom some of the best known are William Galston, Will Kymlicka, Bhikhu Parekh, Charles Taylor and Iris Marion Young. According to them, this 'difference-blind' conception of liberal equality fails to deliver either liberty or equal treatment. In its place, they propose that the state should 'recognize' group identities, by granting groups exemptions from certain laws, publicly 'affirming' their value, and by providing them with special privileges or subsidies. In Culture and Equality, Barry offers an incisive critique of these arguments and suggests that theorists of multiculturism tend to misdiagnose the problems of minority groups. Often, these are not rooted in culture, and multiculturalist policies may actually stand in the way of universalistic measures that would be genuinely beneficial. (shrink)

Both an introduction to Nietzsche’s moral philosophy, and a sustained commentary on his most famous work, On the Genealogy of Morality, this book has become the most widely used and debated secondary source on these topics over the past dozen years. Many of Nietzsche’s most famous ideas - the "slave revolt" in morals, the attack on free will, perspectivism, "will to power" and the "ascetic ideal" - are clearly analyzed and explained. The first edition established the centrality of naturalism to (...) Nietzsche’s philosophy, generating a substantial scholarly literature to which Leiter responds in an important new Postscript. In addition, Leiter has revised and refreshed the book throughout, taking into account new scholarly literature, and revising or clarifying his treatment of such topics as the objectivity of value, epiphenomenalism and consciousness, and the possibility of "autonomous" agency. (shrink)

In recent years, the project of providing microeconomic foundations for macroeconomics has taken on new urgency. Some philosophers and economists have challenged the project, both for the way economists actually approach microfoundations and for more general anti-reductionist reasons. Reductionists and anti-reductionists alike, however, have taken it to be trivial that the macroeconomic facts are exhaustively determined by microeconomic ones. In this paper, I challenge this supposed triviality. I argue that macroeconomic properties do not even globally supervene on microeconomic ones. This (...) is simply a consequence of the difference in the explanatory goals of the respective fields, which implicitly carve out the microeconomic property set in such a way that it underdetermines macroeconomic properties. It means, however, that microeconomics-based foundations for macroeconomics are inadequate in principle. (shrink)

This paper presents three studies exploring the relationship between emotional responses to classic cognitive developmental moral dilemmas and moral reasoning indices as measured by the Defining Issues Test (DIT). Each study indicated that certain moral dilemmas elicit varying levels of anger and sadness as compared to a neutral baseline. In each study, decreased moral reasoning was observed in those instances where reports in both sadness and anger were high following a dilemma. This did not occur, however, in those instances where (...) only sadness or anger was high following a dilemma. Affective inductions prior to taking the DIT (study 3) did not impact trends beyond that found for individual moral dilemmas in studies 1 and 2. Although certain dilemmas elicited affective states that temporarily influenced reasoning, in general participants? reasoning levels stayed consistent across dilemmas. Results are discussed in terms of the role of affect on the moral judgment process. (shrink)

Extremism about Demands is the view that morality is significantly more demanding than prevailing common-sense morality acknowledges. This view is not widely held, despite the powerful advocacy on its behalf by philosophers such as Peter Singer, Shelly Kagan, Peter Unger, and G.A. Cohen. Most philosophers have remained attracted to some version of Moderation about Demands, which holds that the behavior of typical well-off people is permissible, including the ways that such people tend to employ their economic and other resources. It (...) is difficult to resist the conclusion that proponents of Extremism have not taken sufficiently seriously the central convictions that motivate the Moderate view. -/- This dissertation offers an improved defense of Extremism about Demands. At its center is an argument that appeals dialectically to requirements of justice that Moderates themselves already implicitly accept. Specifically, I claim that any plausible set of Moderate moral principles will, when applied to a world like ours, yield demands on typical well-off people that far exceed the demands of common-sense morality. -/- My argument has two cruxes. The first is the idea that our concern for justice is at least partially grounded in a concern for individuals’ interests, broadly construed. The other is a principle that I call Injustice entails Obligations, which says that we are collectively subject to requirements of justice that, if fully complied with, would ensure the transition from current injustice to a just state of affairs. Any view that is compatible with both the interest-based view of (part of) our concern for justice and Injustice entails Obligations will, I argue, require sacrifices from typical well-off people that substantially exceed what prevailing common-sense morality requires of them. -/- Moderates typically emphasize the idea that each person has an important interest in pursuing the projects, plans, relationships, and commitments that are most important to her. But they also believe that acceptable Moderate principles will properly balance this idea with the idea that from a properly impartial perspective everyone, and everyone's interests, are equally morally important. Because Moderates accept the latter idea, they are already committed to thinking that in a just world, everyone would have a sufficient minimum share of society’s resources. I argue that even if we limit our focus to distributive justice in a single society such as the United States, and even if we assume that distributive justice requires only a sufficient minimum, the extent to which the status quo must be transformed in order for justice to be achieved is still too great to be compatible with Moderate demands on typical well-off people. -/- There are a number of ways to try to argue that Moderate principles and Injustice entails Obligations are compatible with Moderation about Demands. For instance, it might be argued that all or nearly all of the demands to sacrifice in order to promote justice can be assigned to the super-rich, rather than to typical well-off people. Or it might be argued that the sacrifices of a single well-off person cannot be required because they amount to a mere “drop in the bucket” relative to what needs to be done in order to fully achieve justice. I show that such arguments fail. -/- The argument that I consider in greatest detail derives from John Rawls’s view that the principles of justice apply to the institutions of the “basic structure of society,” and do not apply directly to the conduct of individuals. If this “Institutionalism” is right, then it cannot be the case that individuals are obligated to promote justice directly in the way that I suggest they are. Furthermore, it might seem that a view that assigns all of the burdens of promoting justice to the basic structure satisfies the imperative to transition from injustice to justice, since if the relevant institutions were to begin doing everything that the Rawlsian view says they ought to be doing, the requirements of justice would be met. I argue, however, that there is no understanding of Institutionalism on which it is itself consistent with the following desiderata: Moderate principles, and the associated interest-based view of (part of) the ground of our concern for justice; Injustice entails Obligations; and Moderate demands. So, Institutionalism cannot make Moderate principles and Injustice entails Obligations compatible with Moderate demands. -/- Moderate principles and Injustice entails Obligations, then, remain incompatible with Moderation about Demands. Since there are compelling reasons to accept both Moderate principles and In justice entails Obligations, I conclude that we must reject Moderation about Demands. The obligations that justice places on typical well-off people are substantially more extensive than is acknowledged by prevailing common-sense morality. (shrink)

This thesis is about toleration as a modality of citizenship for pluralistic societies. Its central argument is that the current dissatisfaction with "mere" toleration which we find so broadly represented in our public and scholarly cultures is based on an underestimation of the capacities and attitudes that toleration entails. The liberal recasting of toleration, sophisticated and indeed invaluable though it is abets this devaluation by focusing too exclusively on public justification and on the Lockean stream of the tradition from which (...) we draw. ;The present thesis begins by tracing some of the difficulties facing the Rawlsian and Habermasian projects if we accept a vivid picture of the pluralisms amidst which we live. It then sketches the central features of a complementary tradition of toleration as it flows to us through the works of Montaigne, William James, Mikhail Bakhtin and others. An attempt is made to show where the resources drawn from this tradition might fit in to a theory of citizenship given reasonable Rawlsian qualms about "thick" public conceptions and given the fissiparous nature of a civil society like ours. The thesis ends with a pair of empirically oriented chapters which show ways in which we could conceive a praxis of toleration which might respond to the issues raised in the earlier sections of the work. (shrink)

Ernest Adams has claimed that a probabilistic account of validity gives the best account of our intuitive judgements about the validity of arguments. In particular, he claims, it has the best hope of accounting for our judgements about many arguments involving conditionals. Most of the examples in the literature on this topic have been arguments framed in the language of propositional logic. I show that once we consider arguments involving predicates and involving identity, Adams’s strategy is less successful.

An important tradition in metaphysics takes its job to be finding a limited number of ingredients with which we can tell the complete story of the world (or some subject matter). Physicalism, for example, claims that the list of ingredients sufficient to tell the complete story about the very small, or about the non-sentient, is sufficient to tell the complete story about all of the world. Some people take the moral of this kind of metaphysics to be eliminativist; that we (...) can tell the complete story of the world without meanings, or inflations, shows that meaning and inflation do not exist. Most people are not so blasé about rejecting commonsense opinions. Inflations, wars, rivers and beliefs all exist, but there is nothing but atoms in the void, so we must find a way of showing that the arrangement of atoms in the void makes true the stories about inflations and so on. (shrink)

David Eaton and Timothy Pickavance argued that interest-relative invariantism has a surprising and interesting consequence. They take this consequence to be so implausible that it refutes interest-relative invariantism. But in fact it is a consequence that any theory of knowledge that has the resources to explain familiar puzzles must have.

The view of Thomas Aquinas that we can only know what God is not, rather than what he is, is discussed. The first part of the chapter outlines Aquinas’ basic position on this matter in relation to his theological background and the range of human knowledge. It then goes on to discuss the doctrine of divine simplicity, first giving the reasoning behind this, and then giving the details of Aquinas’ view on the matter. This is that God is pure form (...) and he is his nature, so that the substance of God is his existence. Although God may be unknowable and incomprehensible, he is still there. (shrink)

This chapter contains sections titled: Introduction Why the Blues will Always be With Us Why Epictetus Never Sang the Blues Akrasia, or ‘I can't help myself’ Objections (‘This Life Sounds Horrible!’) I Can't Get No Satisfaction, and I Like it, I Like it, Yes I Do In Place of a Conclusion.

Natural Catastrophe is an original contribution to the growing field of the environmental humanities. It offers an unorthodox reckoning with the narrative of natural catastrophe that sustains both environmental and neoliberal solutions to the problem of climate change and calls for a return to the radical experiments in political thought seen in the nineteenth century.’ Janet Stewart, Durham University A lively introduction to the social and political dimensions of the current climate change and sustainability debates The voices proclaiming that climate (...) change is a natural catastrophe grow ever more strident. This book offers the persuasive alternative argument that climate change is in fact a profoundly political phenomenon and a symptom of neoliberal governance. Viewing it as such helps us to understand how, across wealthy liberal democracies, environmental concern has increasingly been framed as a consumer responsibility issue rather than as a matter of structural social–political transformation. Thinking of a world truly beyond climate change requires us to reimagine the state beyond its current neoliberal configuration. This book argues that, in order to achieve this, environmental politics in the West needs to renew the Marxist challenge to the global market’s benign production of social utility and construct a new non-apocalyptic politics of nature. (shrink)

This paper offers an interpretation of the dramatic setting of Plato’s Phaedrus as an allegory of the situation of the philosopher within Plato’s Athens. Following Jean-Pierre Vernant’s work on the place of class struggle and warfare within the ancient Greek city-state in his Myth and Society in Ancient Greece I decipher key passages on the Phaedrus as implicit responses to Plato’s experience of the city. The key themes that emerge are: the relation between the country and the city; the connection (...) between leisure, luxury, and territorial expansion; the prospects for philosophical rule in the city; and the assessment of writing as a product of urban and commercial development. In my concluding paragraphs I suggest that Plato’s dialogues should more generally be regarded as a confrontation with the social conditions of the city-state as Plato experienced them. I also suggest that Platonic writings such as the Phaedrus are best interpreted allegorically as well as literally to ensure that multiple levels of meaning are drawn out through close analysis. (shrink)

Justificatory neutrality, as held by Nagel, holds that the state is only legitimate if it can be justified on the basis of the value-beliefs that we all share. I argue that this theory has faults that are avoided by Rawls’s alternative of stability for the right reasons as achieved by a reasonable overlapping consensus on the political norms for regulating the basic structure of society. However, neither approach explains why we should be concerned with people’s value-beliefs, a gap which I (...) begin to fill. I argue that justificatory neutrality is inadequate in two ways. Firstly, neutrality cannot serve as a guiding ideal, in that we must appeal to other values in order to determine when and how we should be neutral. Secondly, in excluding all controversial ideals, it has no guarantee that a) those values shared will be adequate for settling political questions, and/or b) that some of those values excluded aren’t significant to the people who believe in them in ways that prevent their accepting justifications that appeal solely to the shared values. I argue that Rawls’s theory avoids these problems but that his idea of public reason is both unnecessary and in tension with the aspiration to achieve an actual reasonable overlapping consensus. Drawing on Raz I argue that neither Nagel nor Rawls offer adequate explanations of why we should be concerned with justifiability to people on the basis of their value-beliefs. I provide such an explanation in terms of the value of being able to endorse the course of our own lives. This value grounds reasons to be responsive to people’s (possibly mistaken) value-beliefs in political justifications – though, since this is not the only value to be considered, sometimes other reasons may settle the matter. (shrink)

ABSTRACT In Barker and Dowe, Stephen Barker and Phil Dowe present a range of arguments which they take to demonstrate the paradoxical nature of endurantism. I claim that the endurantist has convincing replies to each argument.

Philosophy, by and large, tends to dwell on what might be called the woeful nature of reality—finitude, suffering, loss, death, and the like. While these topics are no doubt worthy of philosophical concern, undue focus on them tends to obscure other facets of our experience and of reality, giving philosophy a temperament that could justifiably be called melancholic. Without besmirching the value of such inquiry, this paper suggests that philosophers have largely ignored the experience of joy and, consequently, missed its (...) distinctive contributions to our understanding of the meaningfulness of life and the goodness of being. Traditional accounts of the problem of evil are rooted in what John D. Caputo calls “strong theology,” which tends to construe evil as a problem to which God should supply the answer or solution. However, if we call into question traditional accounts of omnipotence, evil ceases to be a problem, and we become free to engage it as part of what Gabriel Marcel calls “the mystery of being.” Thus liberated, we are free to assess more clearly phenomena missed by melancholic accounts of being, among them the experience of joy, attested to in diverse forms of philosophy, literature, memoir, and elsewhere. (shrink)

One of the central points of Derrida’sArchive Fever is that the nature of the “archive” affects not only what is archived, but also how we relate to and access it. The archive also conditions the process of archiving itself and, indeed, the very nature of what is archivable. Derrida's comments, however, were made in 1995, when the full extent of the Internet boom was only beginning to become evident. The intervening years have reshaped the archive in ways that Derrida could (...) scarcely have foreseen in 1995. Although many of the changes bear out his fundamental theses, the power that the Internet has come to exert over public and private discourse demands that we re-examine the archive in order to begin to assess what these changes portend. (shrink)

Since its founding in 1950, the Metaphysical Society of America has remained a pluralistic community dedicated to rigorous philosophical inquiry into the most basic metaphysical questions. At each year’s conference, the presidential address offers original insights into metaphysical questions. Both the insights and the questions are as perennial as they are relevant to contemporary philosophers. This volume collects eighteen of the finest representatives from those presidential addresses, including contributions from George Allan, Richard Bernstein, Norris Clarke, Vincent Colapietro, Frederick Ferré, Jorge (...) J. E. Gracia, Joseph Grange, Marjorie Grene, George Klubertanz, Ivor Leclerc, Ralph McInerny, Ernan McMullin, Joseph Owens, John Herman Randall, Jr., Nicholas Rescher, Stanley Rosen, John E. Smith, and Robert Sokolowski. Also included are Paul Weiss’s inaugural address to the Society, an introduction chronicling the history of the Society, and an original Foreword by William Desmond and Epilogue by Robert Neville. (shrink)