Was Descartes a Cartesian Dualist? In this controversial study, Gordon Baker and Katherine J. Morris argue that, despite the general consensus within philosophy, Descartes was neither a proponent of dualism nor guilty of the many crimes of which he has been accused by twentieth century philosophers. In lively and engaging prose, Baker and Morris present a radical revision of the ways in which Descartes' work has been interpreted. Descartes emerges with both his historical importance assured and his philosophical importance (...) redeemed. (shrink)

What is epistemic self-trust? There is a tension in the way in which prominent accounts answer this question. Many construe epistemic trust in oneself as no more than reliance on our sub-personal cognitive faculties. Yet many accounts – often the same ones – construe epistemic trust in others as a normatively laden attitude directed at persons whom we expect to care about our epistemic needs. Is epistemic self-trust really so different from epistemic trust in others? I argue that it is (...) not. We certainly do rely on our cognitive faculties to achieve epistemic ends; but I argue that we also have the normatively rich sort of epistemic trust in ourselves. Moreover, there is a theoretical need for this normatively rich notion of epistemic self-trust: positing it yields the best account of how we secure important epistemic goods, including knowledge and recognition as knowers. I argue this by giving an account of epistemic trust in others and showing that it can be generalized to epistemic trust in oneself. (shrink)

Scientific researchers welcome disagreement as a way of furthering epistemic aims. Religious communities, by contrast, tend to regard it as a potential threat to their beliefs. But I argue that religious disagreement can help achieve religious epistemic aims. I do not argue this by comparing science and religion, however. For scientific hypotheses are ideally held with a scholarly neutrality, and my aim is to persuade those who arecommittedto religious beliefs that religious disagreement can be epistemically beneficial for them too.

ABSTRACT Is it good to form positive beliefs about those you have faith in, such as God or a religious community? Doxastic partialists say that it is. Some hold that it is good, from the viewpoint of faith, to form positive beliefs about the object of your faith even when your evidence favours negative ones. Others try to maintain respect for evidence by appealing to a highly permissive epistemology. I argue against both forms of doxastic partiality, on the grounds that (...) they foster an epistemically problematic noetic entrenchment. I instead defend evidentialism—the view that it is good to strive for true beliefs about the object of your faith, be they positive or negative, given relatively stringent evidential norms. I address the objection that evidentialism fosters disloyalty to the other party, not least because it risks losing your faith altogether. What emerges are not just epistemic norms for beliefs about religious matters, but an evidentialist account of what makes for good faith itself. (shrink)

Where there is trust, there is also vulnerability, and vulnerability can be exploited. Epistemic trust is no exception. This chapter maps the phenomenon of the exploitation of epistemic trust. I start with a discussion of how trust in general can be exploited; a key observation is that trust incurs vulnerabilities not just for the party doing the trusting, but also for the trustee (after all, trust can be burdensome), so either party can exploit the other. I apply these considerations to (...) epistemic trust, specifically in testimonial relationships. There, we standardly think of a hearer trusting a speaker. But we miss an important aspect of this relationship unless we consider too that the speaker standardly trusts the hearer. Given this mutual trust, and given that both trustees and trusters can exploit each other, we have four possibilities for exploitation in epistemic-trust relationships: a speaker exploiting a hearer (a) by accepting his trust or (b) by imposing her trust on him, and a hearer exploiting a speaker (c) by accepting her trust or (d) by imposing his trust on her. One result is that you do not need to betray someone to exploit him – you can exploit him just as easily by doing what he trusts you for. (shrink)

If you love someone, is it good to believe better of her than epistemic norms allow? The partiality view says that it is: love, on this view, issues norms of belief that clash with epistemic norms. The partiality view is supposedly supported by an analogy between beliefs and actions, by the phenomenology of love, and by the idea that love commits us to the loved one’s good character. I argue that the partiality view is false, and defend what I call (...) the epistemic view. On the epistemic view, love also issues norms of belief. But these say simply that you should adhere to epistemic norms in forming and maintaining beliefs about loved ones. I offer two arguments for the epistemic view. The first appeals to the emotional responses of love, which, when sensitive to what the loved one is really like, can make love great and be morally transformative. The second is a new argument for why caring for a loved one requires true beliefs about him. We see that there may be some boundaries, such as stuffy traditions, that love is right to defy, but that epistemic boundaries are not among them. (shrink)

I give an overview of the trust literature and then of six central issues concerning epistemic trust. The survey of trust zeroes in on the kinds of expectations that trust involves, trust’s characteristic psychology, and what makes trust rational. The discussion of epistemic trust focuses on its role in testimony, the epistemic goods that we trust for, the significance of epistemic trust in contrast to reliance, what makes epistemic trust rational, and epistemic self-trust.

Ontology is the philosophical discipline which aims to understand how things in the world are divided into categories and how these categories are related together. This is exactly what information scientists aim for in creating structured, automated representations, called 'ontologies,' for managing information in fields such as science, government, industry, and healthcare. Currently, these systems are designed in a variety of different ways, so they cannot share data with one another. They are often idiosyncratically structured, accessible only to those who (...) created them, and unable to serve as inputs for automated reasoning. This volume shows, in a nontechnical way and using examples from medicine and biology, how the rigorous application of theories and insights from philosophical ontology can improve the ontologies upon which information management depends. (shrink)

I argue that faith is a type of trust. It is also part of a relationship in which both parties are called on to be faithful, where faithfulness is a type of trustworthiness. What distinguishes faith relationships from trust relationships is that both parties value the faith relationship intrinsically. I discuss how faith on this account can, and cannot, be rational when it goes beyond a person’s evidence. It turns out that faith has the same rationality conditions as trust, differing (...) from it only in the cases that fix our intuitions. (shrink)

In a fallen world fraught with evidence against religious beliefs, it is tempting to think that, on the assumption that those beliefs are true, the best way to protect them is to hold them dogmatically. Dogmatic belief, which is highly confident and resistant to counterevidence, may fail to exhibit epistemic virtues such as humility and may instead manifest epistemic vices such as arrogance or servility, but if this is the price of secure belief in religious truths, so be it. I (...) argue, however, that even in a world full of misleading evidence against true religious beliefs, cultivating epistemic humility is the better way to achieve believers’ epistemic aims. The reason is that dogmatic belief courts certain epistemic dangers, including to the true religious beliefs themselves, whereas epistemic humility empowers believers to counter them. (shrink)

Aristotle’s Metaphysics Θ.8 argument for the priority of actuality to potentiality poses an immediate interpretive problem: the argument uses two distinct tests for priority, one of which threatens to reverse the results of the other. This paper argues that the standard approach to this passage, according to which one thing is prior to another when it satisfies the ontological independence test from Metaphysics Δ.11, fails to secure the argumentative unity of the passage. It introduces a new, causal account of priority (...) which explains both Aristotle’s claims about priority and the way he argues for them. (shrink)

Motivating reforms to address discrimination and exclusion is important. But what epistemic practices characterize better or worse ways of doing this? Recently, the phenomena of implicit biases have played a large role in motivating reforms. We argue that this strategy risks perpetuating two kinds of epistemic oppression: the vindication dynamic and contributory injustice. We offer positive proposals for avoiding these forms of epistemic oppression when confronting racism.

Should religious believers proportion their religious beliefs to their evidence? They should: Religious faith is better, ceteris paribus, when the beliefs accompanying it are evidence-proportioned. I offer two philosophical arguments and a biblical argument. The philosophical arguments conclude that love and trust, two attitudes belonging to faith, are better, ceteris paribus, when accompanied by evidence-proportioned belief, and that so too is the faith in question. The biblical argument concludes that beliefs associated with faith, portrayed in the Hebrew Bible and the (...) New Testament, are typically, and normatively, exhorted on the basis of evidence. I hope to convince religious believers and nonbelievers alike that religious beliefs should be evidence-proportioned. (shrink)

Gatekeeping, or determining membership of your group, is crucial to science: the moniker ‘scientific’ is a stamp of epistemic quality or even authority. But gatekeeping in science is fraught with dangers. Gatekeepers must exclude bad science, science fraud and pseudoscience, while including the disagreeing viewpoints on which science thrives. This is a difficult tightrope, not least because gatekeeping is a human matter and can be influenced by biases such as groupthink. After spelling out these general tensions around gatekeeping in science, (...) we shed light on them with a case study from psychology. This concerns whether academic psychologists rightly or wrongly classify the applied-psychology framework of NLP (‘neuro-linguistic programming’) as unscientific and even pseudoscientific. This example of gatekeeping is particularly instructive because both the NLP community and the psychology community, we argue, make legitimate but also illegitimate moves. This case gives rise to several general insights about gatekeeping in science more generally. (shrink)

A collection of essays with themes in human rights and legal history, spanning several centuries, containing a tribute to one of the most remarkable jurists of our time. Linked by an historical and contextual approach, these essays add to knowledge of legal history and human rights and provide a reference point for future research.

Some religious communities argue that public policy is best decided by their own members, on the grounds that collaborating with those reasoning from secular or “worldly” perspectives will only foment error about how society should be run. But I argue that epistemology instead recommends fostering disagreement among a plurality of religious and secular worldviews. Inter-worldview disagreement over public policy can challenge our unquestioned assumptions, deliver evidence we would likely have missed, and expose us to new epistemic alternatives; when done respectfully, (...) it can also combat epistemically problematic biases and groupthink. I address two objections that members of a politically active religious community might raise: one that inter-worldview disagreement about public policy is not needed because one’s own beliefs are already true, and another that it is not needed because one’s own beliefforming processes are divinely guided. (shrink)

Religious disagreement, like disagreement in science, stands to deliver important epistemic benefits. But religious communities tend to frown on it. A salient reason is that, whereas scientists should be neutral toward the topics they discuss, religious believers should be loyal to God; and religious disagreement, they argue, is disloyal. For it often involves discussion with people who believe more negatively about God than you do, putting you at risk of forming negative beliefs yourself. And forming negative beliefs about someone, or (...) even being open to doing so, is disloyal. A loyal person, says the objector, should instead exhibit doxastic partiality, doing her best to believe positively about the other party even at the cost of accuracy. I discuss two arguments from doxastic partiality that aim to show that religious disagreement is typically disloyal. I argue that even given doxastic partiality, religious disagreement is not typically disloyal, and can in fact be loyal. But then I argue that doxastic partiality is false. A superior form of loyalty is epistemically oriented: concerned with knowing the other party as she really is. This opens up new ways in which religious disagreement for the sake of learning about God can be loyal to him. (shrink)

Trust is fundamental to epistemology. It features as theoretical bedrock in a broad cross-section of areas including social epistemology, the epistemology of self-trust, feminist epistemology, and the philosophy of science. Yet epistemology has seen little systematic conversation with the rich literature on trust itself. This volume aims to promote and shape this conversation. It encourages epistemologists of all stripes to dig deeper into the fundamental epistemic roles played by trust, and it encourages philosophers of trust to explore the epistemological upshots (...) and applications of their theories. The contributors explore such issues as the risks and necessity of trusting others for information, the value of doing so as opposed to relying on oneself, the mechanisms underlying trust’s strange ability to deliver knowledge, whether depending on others for information is compatible with epistemic responsibility, whether self-trust is an intellectual virtue, and the intimate relationship between epistemic trust and social power. (shrink)

Since the first draft of the human genome was published in 2001, DNA sequencing technology has advanced at a remarkable pace. Launched in 1990, the Human Genome Project sought to sequence all three billion base pairs of the haploid human genome, an endeavor that took more than a decade and cost nearly three billion dollars. The subsequent development of so-called “next generation” sequencing methods has raised the possibility that real-time, affordable genome sequencing will soon be widely available. Currently, NGS methods (...) can be used to sequence up to 60 billion base pairs per day. Whole-genome sequencing costs an estimated $5,000-10,000, with that number predicted to fall to $1000 in the near future.In the past few years, the availability of high-throughput NGS methods has led to a proliferation of potential and actual clinical applications for NGS. NGS therefore has the potential to usher in the long-awaited era of personalized medicine. (shrink)

Intellectual humility has something important in common with trust: both, independently, help secure knowledge. But they also do so in tandem, and this chapter discusses how. Intellectual humility is a virtue of a person’s cognitive character; this means that it disposes her to perceive and think in certain ways that help promote knowledge. Trust is a form of cooperation, in which one person depends on another (or on herself) for some end, in a way that is governed by certain norms. (...) Epistemic trust is trust for epistemic ends, where the one that I will focus on here is knowledge. When the parties to an epistemic-trust relationship exhibit intellectual humility, I will argue, they are in a better position than otherwise to secure knowledge. Some think that this is true trivially, on the grounds that knowledge (on their view) is constituted by the exercise of epistemic virtues. Whether or not this is so, I will focus on two different ways in which intellectual humility makes epistemic trust knowledge-conducive: first, it equips trusters to invest trust effectively – that is, in those who are trustworthy; second, it equips trustees to be epistemically trustworthy. (shrink)

The stories in this volume shed light on the potential of narrative inquiry to fill gaps in knowledge, particularly given the mixed results of quantitative research on patient views of and experiences with genetic and genomic testing. Published studies investigate predictors of testing (particularly risk perceptions and worry); psychological and behavioral responses to testing; and potential impact on the health care system (e.g., when patients bring DTC genetic test results to their primary care provider). Interestingly, these themes did not dominate (...) the narratives published in this issue. Rather, these narratives included consistent themes of expectations and looking for answers; complex emotions; areas of contradiction and conflict; and family impact. More narrative research on patient experiences with genetic testing may fill gaps in knowledge regarding how patients define the benefits of testing, changes in psychological and emotional reactions to test results over time, and the impact of testing on families. (shrink)

The COVID-19 Law Lab platform enables quantitative representation of epidemic law and policies in a given country for multiple years, enabling governments and researchers to compare countries, and learn about the impacts and drivers of policy choices. The Law Lab initiative is designed to address the urgent need for quality legal information to support the study of how law and policy can be used to effectively manage this, and future, pandemic(s).

Type II DNA topoisomerase activity is required to change DNA topology. It is important in the relaxation of DNA supercoils generated by cellular processes, such as transcription and replication, and it is essential for the condensation of chromosomes and their segregation during mitosis. In mammals this activity is derived from at least two isoforms, termed DNA topoisomerase IIα and β. The α isoform is involved in chromosome condensation and segregation, whereas the role of the β isoform is not yet clear. (...) DNA topoisomerase IIβ was first reported in 1987. Here we review the research on DNA topoisomerase IIβ over the last 10 years. BioEssays 20:215–226, 1998.© 1998 John Wiley & Sons, Inc. (shrink)

Aristotle is often taken to define priority in being in Metaphysics Δ.11, where he says that those things are prior in being which “admit of being without other things, while these others cannot be without them: a division which Plato used” (1019a3-4). But Aristotle’s pattern of arguments about priority – some of which use Plato’s Test and others of which use distinct, causal tests – looks puzzling if Plato’s Test is his definition. This paper offers a new interpretation of Δ.11 (...) on which it offers a guide to the Aristotelian use of Plato’s Test, given that being is said in many ways, rather than endorsing it as Aristotle’s own definition of priority. This reading illuminates Aristotle’s pattern of arguments in the corpus – explaining why Aristotle uses Plato’s Test in some cases and departs from it in others – and suggests a plausible story about how these arguments were shaped by engaging with Plato. (shrink)

We welcome Ballantyne & Schaefer’s discussion of the issues concerning consent and use of health data for research. In response to their acknowledgement of the need for public debate and discussion, we provide evidence from our own public consultation on this topic.

This paper explains the phenomena that compose the experience of the passage of time and argues that this experience represents the temporal direction of causal processes. The experience of the passage of time comprises several more specific experiences, namely: (1) the experience of continuously advancing to later times; (2) the observation of continuous change, both in the things around us and in ourselves; (3) the feeling of a lack of control over (1) and (2); and (4) the experience of a (...) number of phenomena that we describe as animated, dynamic, or flowing. The experience of passage is a causal process whose function is to promote survival and reproductive success by representing the temporal direction of causal processes (including itself). It does this primarily via the specious present, wherein later content is presented as more vivid than earlier content. The experience of passage is veridical and is compatible with either the B‐theory or the A‐theoretic views of time. (shrink)

This narrative symposium examines the relationship of bioethics practice to personal experiences of illness. A call for stories was developed by Tod Chambers, the symposium editor, and editorial staff and was sent to several commonly used bioethics listservs and posted on the Narrative Inquiry in Bioethics website. The call asked authors to relate a personal story of being ill or caring for a person who is ill, and to describe how this affected how they think about bioethical questions and the (...) practice of medicine. Eighteen individuals were invited to submit full stories based on review of their proposals. Twelve stories are published in this symposium, and six supplemental stories are published online only through Project MUSE. Authors explore themes of vulnerability, suffering, communication, voluntariness, cultural barriers, and flaws in local healthcare systems through stories about their own illnesses or about caring for children, partners, parents and grandparents. Commentary articles by Arthur Frank, Bradley Lewis, and Carol Taylor follow the collection of personal narratives. (shrink)

Sex dimorphism occurs when group means differ by four or more standard deviations. However, the average size of the corpus callosum is greater in males by about one standard deviation in rats, 0.2 standard deviation in humans, and virtually zero in mice. Furthermore, variations in corpus callosum size are related to brain size and are not sex specific.

Wir leben in einem Zeitalter der religiösen Vielfalt. Es gibt viele unterschiedliche und scheinbar inkompatible religiöse und säkulare Glaubensformen, die einander mit einer erstaunlichen Intensität und Geschwindigkeit dank Globalisierung und sozialen Medien begegnen. Damit wächst die Einsicht, dass das eigene Überzeugungssystem nicht mehr einfach als gegeben und plausibel anzunehmen ist. Aufgrund dieser neuen Entwicklungen haben sich in den letzten Jahren intensive philosophische Diskussionen ergeben.

This paper seeks to show the proximity between the phenomenologicalreflection that Merleau-Ponty presents in the article “The War Has Taken Place”, and the stories of Jose Carlos Agüero, in his book, Los rendidos. From a phenomenological perspective, both authors describe the experience of pain, shame and forgiveness as the pursuit of freedom and justice. The text is divided into two parts. In the first part, we present discourses of justice which were established after the Peruvian armed conflict and the need (...) of exercising the phenomenological “epochè” in order to describe the feelings of terror and shame that underlie as background of this shared experience. In the second part, supported by Merleau Ponty’s concepts of intersubjectivity and historicity, we define freedom as the pursuit of justice, which can only be understood at the primordialaction of being in relation with others, from which we give meaning to the past. (shrink)

Wegen der Globalisierung und der Säkularisierung ist heute nicht mehr selbstverständlich davon auszugehen, dass die eigenen religiösen Überzeugungen richtig sind. Wie können Gläubige darauf reagieren? Eine nachvollziehbare Reaktion wäre zu versuchen, das eigene religiöse Glaubenssystem vor aller scheinbaren Konkurrenz zu schützen, indem man religiösen Dissens innerhalb oder außerhalb der Glaubensgemeinschaft unterbindet oder unterdrückt. Die Autorin argumentiert jedoch dafür, dass die Förderung von solchem Dissens die religiöse Erkenntnis eigentlich begünstigt und zwar selbst für diejenigen, die ihr eigenes religiöses Glaubenssystem möglichst bewahren (...) wollen. (shrink)

Spelling is a fundamental literacy skill facilitating word recognition and thus higher-level reading abilities via its support for efficient text processing (Adams, 1990; Joshi et al., 2008; Perfetti and Stafura, 2014). However, relatively little work examines second language (L2) spelling in adults, and even less work examines learners from different first language (L1) writing systems. This is despite the fact that the influence of L1 writing system on L2 literacy skills is well documented (Hudson, 2007; Koda and Zehler, 2008; Grabe, (...) 2009). To address this shortcoming, this study collected data on real word spelling, pseudoword spelling, and phonological awareness (elision) abilities from 70 participants (23 native speakers; 47 ELLs with alphabetic, abjad, and morphosyllabic L1s). Analyses compared performance on real word and pseudoword spelling between L1 English speakers and ELLs, and additionally among the non-native-speaker L1 groups (categorized into alphabet, abjad, and morphosyllabary groups). Similar comparisons were made across groups for performance on phonological awareness. Further, correlations were calculated between phonological awareness and real word spelling and between phonological awareness and pseudoword spelling, separately for L1 English speakers and the various ESL groups. Spelling accuracy on real words and pseudowords as well as phonological awareness skill differed between native speakers and ESL speakers, and also varied by the ESL speakers’ L1 writing system. Theoretically interesting patterns emerged in the spelling data. For example, the morphosyllabic L1 speakers had strong real word spelling (better than the other ESL groups) but greatly decreased pseudoword accuracy (a drop of 59% in accuracy). Although alphabetic L1 speakers had low spelling accuracy in terms of strict scoring, they had lower rates of errors per item, highlighting the importance of scoring approach for shaping the conclusions that are drawn. Error rates also revealed vowels to be more problematic than consonants, particularly in abjad L1 speakers. The results demonstrate that L2 spelling abilities, phonological awareness, and the relationships among them vary by L1 writing system, and that differing approaches to scoring and analysis may lead to varying conclusions. (shrink)