The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

We examine whether the level of integrity in a society, i.e., social integrity, affects stock price crash risk. We explore two competing hypotheses. On the one hand, exposure to high levels of integrity may reduce managers’ incentives to obfuscate information, thereby leading to lower crash risk. On the other hand, social integrity may weaken outsiders’ monitoring of managerial behaviors, thus giving managers more opportunities to obfuscate information and, consequently, leading to higher crash risk. Using a sample of Chinese listed firms, (...) we find that firms located in regions with higher integrity have lower future stock price crash risk. This result is confirmed by a difference-in-difference analysis with an exogenous shock to social integrity. Further analysis suggests that increased information transparency is a potential channel through which social integrity affects stock price crash risk. Cross-sectional analyses suggest that the negative effect of social integrity on crash risk is more pronounced in firms with weaker internal control systems and firms with less negative media coverage. Overall, our study provides novel evidence that the ethical environment plays a significant role in shaping business ethics and influencing stock price crash risk. (shrink)

Housed in one volume for the first time are several of the seminal essays on Du Bois's contributions to sociology and critical social theory: from DuBois as inventor of the sociology of race to Du Bois as the first sociologist of American religion; from Du Bois as a pioneer of urban and rural sociology to Du Bois as innovator of the sociology of gender and culture; and finally from Du Bois as groundbreaking sociologist of education and cultural criminologist to Du (...) Bois as critic of the disciplinary decadence of the discipline of sociology. Unlike any other anthology or critical reader on Du Bois, this new volume offers an excellent overview of the critical commentary on arguably one of the most imaginative and innovative, perceptive and prolific founders of the discipline of sociology. (shrink)

A moving cultural biography of abolitionist martyr John Brown, by one of the most important African-American intellectuals of the twentieth century. In the history of slavery and its legacy, John Brown looms large as a hero whose deeds partly precipitated the Civil War. As Frederick Douglass wrote: "When John Brown stretched forth his arm... the clash of arms was at hand." DuBois's biography brings Brown stirringly to life and is a neglected classic.

'The problem of the twentieth-century is the problem of the color-line.' Originally published in 1903, The Souls of Black Folk is a classic study of race, culture, and education at the turn of the twentieth century. With its singular combination of essays, memoir, and fiction, this book vaulted W. E. B. Du Bois to the forefront of American political commentary and civil rights activism. The Souls of Black Folk is an impassioned, at times searing account of the situation of African (...) Americans in the United States. Du Bois makes a forceful case for the access of African Americans to higher education, memorably extols the achievements of black culture (above all the spirituals or 'sorrow songs'), and advances the provocative and influential argument that due to the inequalities and pressures of the 'race problem', African American identity is characterized by 'double consciousness'. This edition includes a valuable appendix of other writing by Du Bois, which sheds light on his attitudes and intentions. ABOUT THE SERIES: For over 100 years Oxford World's Classics has made available the widest range of literature from around the globe. Each affordable volume reflects Oxford's commitment to scholarship, providing the most accurate text plus a wealth of other valuable features, including expert introductions by leading authorities, helpful notes to clarify the text, up-to-date bibliographies for further study, and much more. (shrink)

With the rapid development of urbanization, the urban expansion morphology has been changing with complex driving mechanisms behind the urban evolution process. This article simulates the results of urban land development contingent upon decision-makers’ risk preferences and reveals the inherent law of the effect of risk preferences on urban expansion morphology. Results show that cautious decision-makers lead to the urban expansion morphology being relatively compact, and the reckless decision-makers lead the urban expansion to sprawl. Moreover, there are obvious differences in (...) strengths of planning constraints on the decision-makers with different risk preferences. The reckless decision-makers, driven by the economic interests, are more likely to break through the planning, especially when the planning is not reasonable. It is also found that enhancing executive ability of planning for the reckless decision-makers can promote compactness of the urban expansion morphology. However, the effect of enhancing executive ability of planning on the cautious decision-makers is limited. Thus, in the case of unreasonable planning, the executive ability of planning to the reckless decision-makers should be enhanced so as to avoid urban sprawl. (shrink)

This chapter presents an essay by W. E. B. Du Bois that deals with the issue of race. He raises questions such as: What is the real meaning of race. What has, in the past, been the law of race development? What lessons has the past history of race development to teach the rising Negro people? He describes the American Negro Academy, which aims at once to be the epitome and expression of the intellect of the black-blooded people of America, (...) the exponent of the race ideals of one of the world's great races. He concludes by outlining a proposed creed for the Academy. (shrink)

The distinguished American civil rights leader, W. E. B. Du Bois first published these fiery essays, sketches, and poems individually nearly 80 years ago in the Atlantic, the Journal of Race Development, and other periodicals. This volume has long inspired readers with its militant cry for social, political, and economic reforms for black Americans.

Corporate social responsibility reporting is becoming mainstream, yet there is limited research on whether and how CSR reports communicate value relevant information. We examine the effects of CSR report readability and tone on future CSR performance and the market reaction around the release of CSR reports. Using a hand-collected dataset of Fortune 500 companies that published stand-alone CSR reports from 2002 to 2014, we find that 1-year-ahead CSR performance is positively associated with the changes in both CSR report readability and (...) tone, suggesting that more readable text and more optimistic tone in a firm’s CSR report are indicative of better future CSR performance. Furthermore, consistent with the view that CSR reports communicate important value relevant information to the market, we document significant market reactions to report readability and tone around the release of CSR reports. Additional analyses suggest that CSR report readability enhances the association between the abnormal returns and the change in CSR report tone, and that the market reaction to CSR report readability is more pronounced for firms with lower analyst following and higher financial opacity. Taken together, our results substantiate the important roles of CSR report readability and tone in communicating future CSR performance and imparting value relevant information to the market. (shrink)

Le but du présent article est d’examiner les relations entre les notions d’action et de subjectivité. Faut-il mettre ces relations au compte d’une expérience de l’action? Une telle hypothèse permet, à première vue, de distinguer ce qui nous arrive ou encore ce qui procède d’une simple réaction à une stimulation, d’une part, des actions que nous initions et dont nous sommes réellement les agents d’autre part. Mais cette vue, si elle a l’intérêt de faire entrer en scène le sujet sous (...) les trait... (shrink)

-Fabrice Luchini, vous lisez l'Evangile de saint Marc? - Pas encore. Avant de plonger dans les Evangiles, je lis Pierre Boutang. C'est du lourd?! Hier soir, je dînais avec François Hollande qui me dit? : "?Vous lisez Boutang?? C'est la passion de mon père?!?" Je lui réponds? : "?Transmettez mon salut admiratif à votre père car un lecteur de Boutang, c'est un costaud.?" Je suis paumé... - Qu'est-ce qui vous attire chez Boutang?? - Le poison de la curiosité. Pourquoi suis-je (...) ainsi happé?? C'est d'un tel niveau philosophique que je n'ai pas les moyens de suivre. Pourtant j'y vais. Autant Nietzsche, je peux facilement m'y mettre, car c'est un styliste poète, autant ces philosophes qui mettent Kant en allemand face à Thomas d'Aquin en latin... je ne fais pas le poids?! (Fabrice Luchini interrogé par Luc Adrian pour Famille chrétienne, le 10 mai 2016.) Ce livre est un manuel pour commencer à lire Boutang, le philosophe français le plus nécessaire et le plus libre du siècle. " Méthode d'investigation sans concession ", " classique modernité ", " courage " sont les mots par lesquels Pierre Boutang rendait compte des tout premiers travaux de son élève en Sorbonne : " Nous sommes ici en présence du véritable commencement d'une oeuvre ". (shrink)

This book is a philosophically-oriented introduction to bioethics. It offers the reader an overview of key debates in bioethics relevant to various areas including; organ retrieval, stem cell research, justice in healthcare and issues in environmental ethics, including issues surrounding food and agriculture. The book also seeks to go beyond simply describing the issues in order to provide the reader with the methodological and theoretical tools for a more comprehensive understanding of current bioethical debates. The aim of the book is (...) to present bioethics as an interdisciplinary field, to explore its close relation to other disciplines (such as law, life sciences, theology and philosophy), and to discuss the conditions under which bioethics can serve as an academically legitimate discipline that is at the same time relevant to society. As a systematic and methodologically rigorous overview, Bioethics: Methods, Theories, Domains will be of particular interest to academics and students in the disciplines of Law, Medicine, Ethics and Philosophy. (shrink)

This study examines the influence of auditor-CEO surname sharing on financial misstatement and further investigates whether the above effect depends on hometown relationship and the rarity of surnames, respectively. Using hand-collected data from China, the findings show that ACSS is significantly positively related to financial misstatement, suggesting that the auditor-CEO ancestry membership elicits the collusion and increases the likelihood of financial misstatement. Moreover, ACSS based upon hometown relationship leads to significantly higher likelihood of financial misstatement, compared with ACSS without hometown (...) relationship. Furthermore, the positive relation between ACSS and financial misstatement is more pronounced for rare surnames than for common surnames. The above findings are robust to sensitivity tests on the basis of different measures of ACSS and financial misstatement, and my conclusions are still valid after using the propensity score matching approach to address the endogeneity concerns. (shrink)

Vincent du Bois est sculpteur sur pierre. Il a appris à tailler le marbre au pied des carrières de Carrare. Mais sa passion pour Michel-Ange ne l'empêche pas de se définir comme un artiste contemporain. De nos jours, le corps à corps avec la matière n'est plus une étape indispensable pour que l'oeuvre prenne forme. Le sculpteur peut programmer une machine pour se charger de ce travail. En tant qu'artiste, mais aussi en tant que penseur et citoyen, Vincent du Bois (...) interroge cette virtualisation de notre société qui contourne le rapport direct avec la matière et le sens du touché en donnant les pleins pouvoirs à la vue.0Il nous montre comment la révolution numérique, phénomène unique par son ampleur dans l'histoire humaine, signe le triomphe de l'abstraction sur la sensation. Vincent du Bois écrit en sculpteur. Il creuse l'essence des choses comme on taille un bloc, procédant par épanelages successifs jusqu'à ce que se révèle la forme sous-jacente. Elle prend ici les traits d'une question : quel pourra être le rôle du corps dans une société vouée aux écrans? (shrink)

"El libro que publicamos hoy no tiene otro fin que servir de guía a los espíritus deseosos de profundizar los problemas generales del Derecho; es una “Introducción” en el sentido más exacto del término. Se trata de orientar progresivamente al lector partiendo de las realidades más simples para llevarlo después hasta los problemas más abstractos. Hemos renunciado deliberadamente a dar a los primeros capítulos un rigor científico. Igualmente, hemos evitado de pronto los términos técnicos, esforzándonos por explicarlos y hacerlos asimilar (...) gradualmente en el curso de la obra". Claude Du Pasquier. (shrink)

Science is king. Every week, headlines announce new breakthroughs in our understanding of the universe, new technologies that will transform our environment, new medical advances that will extend our lives. Science is giving us unprecedented insight into some of the big questions that have challenged humanity ever since we've been able to formulate those questions. Where did we come from? What is the ultimate destiny of the universe? What are the building blocks of the physical world? What is consciousness? This (...) book asks us to rein in this unbridled enthusiasm for the power of science. Marcus du Sautoy explores the limits of human knowledge, to probe whether there is anything we truly cannot know. (shrink)

In this article, the co-editors of the corporate responsibility: quantitative issues section of the journal provide an overview of the quantitative CSR field and offer some new perspectives on where the field is going. They highlight key issues in developing impactful, theory-driven, and ethically grounded research and call for research that examines complex problems facing businesses and the society (e.g., big data and artificial intelligence, political polarization, and the role of CSR in generating social impact). By examining topics that are (...) under-researched, forward-looking, and socially oriented, scholars can expand the boundary of CSR’s substantive domain and produce research that helps businesses act in a long-term, socially responsible way in this quickly evolving, turbulent environment. They also discuss ways to enhance the methodological rigor of quantitative CSR research and encourage scholars to employ cutting-edge, innovative methods to shed light on the micro-level mechanisms of CSR and reveal patterns and relationships hidden in unstructured big data. (shrink)

Les sages-femmes en France incarnent une subtile synthèse du cure et du care, entretenant une ambiguïté qui fonde une partie de leur identité professionnelle et qui brouille les pistes des stéréotypes de genre. En fonction du contexte social et politique qui conditionne leur mode d’exercice, ces professionnel.le.s développent spontanément des stratégies pour équilibrer les tensions qui existent entre ces deux pôles. Elles/ils vont ainsi promouvoir tantôt leurs compétences dans le care comme valeur ajoutée par rapport aux autres acteurs médicaux, tantôt (...) leur expertise médico-technique et leur autonomie de pratique, affirmant ainsi leur appartenance au monde médical et scientifique. Cet article s’inscrit dans une double approche d’analyse en sciences sociales et d’expérience professionnelle de trente années en tant que sage-femme. (shrink)