The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

Objective:The purpose of this study was to describe the current situation of moral distress and to explore its influencing factors among Chinese nurses.Methods:This is an exploratory, descriptive design study. A total of 465 clinical nurses from different departments in three Grade-III, Level-A hospitals in Jinan, Shandong Province, completed the questionnaires, including demographics questionnaire, Chinese version of Moral Distress Scale–Revised, and Job Diagnostic Survey.Ethical considerations:The study was approved by the university ethics board and the local health service director.Results:The total score of (...) Moral Distress Scale–Revised was 36.01 ± 24.02 points. The mean frequency and intensity scores of moral distress were 1.13 ± 0.49 and 1.09 ± 0.58, respectively. The level of moral distress among Chinese clinical nurses was low, and the frequency and intensity of moral distress were on low to moderate level. The level of moral distress experienced by clinical nurses is associated with demographics features and job characteristics, including age, education degree, department, task significance, autonomy, and dealing with others.Conclusion:Our conclusion suggests that hospital and organizational administrations should attach much importance to the moral distress experienced by clinical nurses in China. Further studies should focus on interventions about how to reduce the levels of the frequency and intensity of moral distress among clinical nurses. (shrink)

This timely book offers revealing insights into the changing role of China in world governance as exemplified by the Silk Road Initiative, the People's Republic's first published major initiative for external affairs. Focusing on various aspects of the Silk Road Initiative, particularly those that are largely neglected in current discussions, including culture and philosophy, finance and investment, environmental protection and social responsibility, judiciary and lawyers, the authors explore a wide range of contexts in which China's role as an emerging power (...) in international relations and international law is examined. In the current era of ever-increasing populism, protectionism and challenges to globalization, the authors explore the Chinese philosophy underpinning Chinese norms of regional and international development. Bearing in mind the political and economic uncertainties hampering the establishment of such norms, the authors offer crucial insights into how the Silk Road Initiative could or should be developed and regulated. Given its depth of coverage, the book is an indispensable read for anyone interested in the Initiative and its social-legal implications. (shrink)

This study draws on the substitutes for leadership theory to investigate the association of strengths-based leadership with employee turnover intention and the mediating role of felt obligation for constructive change and the moderating role of job control in the linkage. Data were collected using a three-wave survey from a sample of 317 employees working in a variety of enterprises in China. The multiple regression analyses with bootstrapping procedure were utilized to examine the proposed hypotheses. The results indicate that strengths-based leadership (...) negatively relates to turnover intention and felt obligation for constructive change partially mediates the relationship between strengths-based leadership and turnover intention. Furthermore, job control, acting as a substitute for strengths-based leadership, negatively moderates the indirect relationship between strengths-based leadership and turnover intention via felt obligation for constructive change. This study contributes to the literature of strengths-based leadership and the substitutes for leadership theory by enhancing our understanding of the effect of job control. (shrink)

With the continuous development and improvement of Internet media technologies in China, the influence of livestream e-commerce is becoming increasingly prominent, and an increasing number of people are engaging in consumption activities in this field. It is important to study consumer stickiness in livestream e-commerce to promote economic structure adjustment and innovation-driven development. Therefore, in this study, we adopted the expectation confirmation theory as the theoretical framework and analyzed the ECT and stickiness. The study considered satisfaction as the previous influencing (...) factor of user and consumer stickiness, replaced the continuance intention in the expectation confirmation model with consumer stickiness as the explanatory variable, introduced the variable of perceived playfulness as the value perception after user experience, and established a consumer stickiness factors model. A total of 262 valid questionnaires were collected in this study, and SmartPLS analysis along with interviews were used to justify the limitations of data analysis. The results of the study demonstrated a significant effect of perceived usefulness and confirmation on satisfaction, a significant effect of confirmation on perceived usefulness, a significant effect of satisfaction on stickiness, and a significant effect of confirmation on perceived playfulness. Based on findings from the data analysis and interviews, we further proposed rationalized recommendations, and aimed to provide some theoretical guidance for future research on live streaming. (shrink)

The existing computer technology is used to conduct an in-depth study and analysis of drilling waste treatment, and the results are analyzed by computer simulation optimization algorithms. Based on the system theory, we define the research system, combine the unique characteristics of the technological innovation mechanism of drilling waste treatment, and use the internal and external factors affecting the technological innovation dynamics of drilling waste treatment, such as drilling waste treatment capacity, from the current actual situation. On this basis, factor (...) analysis is used to analyze the factors affecting technological innovation dynamics from both internal and external aspects of the system, establish a system model of technological innovation dynamics of drilling waste disposal, and give the initial values of the simulation model. This will reduce the pollution of the environment and enhance the competitiveness of enterprises. Drilling waste treatment technology is getting increased attention, but at this stage, there is no suitable technology innovation mechanism for drilling waste treatment. Through the simulation trend chart obtained by sensitivity analysis, the key factors in the system are found, and the innovation power mechanism of drilling waste treatment technology is constructed, which provides a basis for the formulation of enterprise technological innovation strategies and the development of technological innovation activities. Research on the dynamic mechanism of drilling waste treatment technology innovation explores a waste treatment mechanism suitable for the drilling industry, so as to promote the steady development of the drilling industry and at the same time provide theoretical support for the treatment of drilling engineering waste. (shrink)

E. Husserl's reflections in Logical Investigations on "Intentional Feelings" and "non-intentional feelings" are significant in both his later ethical explorations and M. Scheler's thought on ethics. Through the incorporation of the views of Husserl and Scheler, we find that the phenomenology of the intentional feeling-acts is not only the foundation of the non-formal ethics of values in Scheler's phenomenology, but also at least the constitutive foundation of the ethics of Husserl's first orientation. /// 胡塞尔在 "逻辑研究" 中对 "意向感受" 和 "非意向感受" 的思考，无论是 (...) 在他后来的伦理学探讨中，还是在舍勒的伦理学思想中，都具有重要的意义。通过 将胡塞尔与舍勒的视域融合，可以发现，意向感受行为现象学不仅是舍勒现象学的 质料的价值伦理学基础，而且至少可以是胡塞尔第一个方向上的伦理学的建构基础。. (shrink)

In studying and researching Mao Zedong's philosophical thought, it is necessary not only to study the relationship between it and Marxist philosophy, but also to study its relationship to China's traditional philosophy.

The Affymetrix GeneChip is a popular microarray platform for genome‐wide expression profiling and has been widely used in functional genomics especially in the classification of cancers. Due to the updating of genome data, much of the genome information with which the chips were designed is out‐of‐date and it has been reported that many of the genes/transcripts on the chips differ from their original definition when mapping the probes to the new genome information. Dai et al. have reported that the updated (...) definition can cause as much as 30–50% discrepancy in the genes selected as differentially expressed on a heart tissue expression profiling dataset. Understanding the nature of this difference is therefore very important for the utilization of the data. In this work, with a large cancer dataset as an example, we compared two major definitions and investigated their effects on classification, clustering, discovery of differentially expressed genes and gene‐set‐based analysis. Results show that the two definitions agree well on clustering and classification results but genes and gene sets discovered as differentially expressed or enriched can be very different. Discoveries based on the Affymetrix definition can cover most of those based on the new definition, but tend to have more false positives. BioEssays 28: 739–746, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

In the intelligent transportation system, the license information can be automatically recognized by the computer and the vehicle can be tracked. Red light running, illegal change of lanes, vehicle retrograde, and other illegal driving events are reasonably recorded. This is undoubtedly an effective help for the traffic police to relieve the huge work pressure. However, in China, a considerable number of vehicle tracking methods have certain limitations in resisting complex external environmental influences. The external environmental factors include but not limited (...) to variable factors such as camera movement, jitter, and severe rain and snow. These factors cannot be controlled well, so the tracking accuracy is greatly reduced. In regard to this, this paper proposes an optimization method for moving vehicle tracking based on SPF. First, according to the size of the overlapping area of the motion area between the two images, the researcher can construct and simplify the vertex adjacency matrix that reflects the characteristics of the undirected bipartite graph. Then according to the corresponding relationship between the vertex adjacency matrix and the regional behavior and vehicle behavior, the researcher completes the regional behavior analysis and vehicle behavior analysis. On this basis, a particle filter vehicle tracking algorithm based on segmentation compensation is introduced, and the vector sum of the tracked segmentation area is used as the final position of the target vehicle. In this way, as many scattered particles fall on the target area as possible, which will greatly improve the efficiency of particle utilization, enhance tracking accuracy, and avoid the problem of tracking failure caused by too fast vehicle movement. Through experimental simulation, it can be seen that the method proposed in this paper can greatly enhance the vehicle tracking ability when tracking vehicles in “complex environments.”. (shrink)

Editors’ AbstractThis articles expresses a strong discontent with Sinologism and argues that its rise is the result of an uncritical application of Said’s Orientalism and postcolonial theory to Sinology, and that its proponents have committed a grave error in treating Sinology as a discourse of ideology full of subjective imaginations, to the neglect of the fact that Sinology is a branch of objective scholarship. After reviewing the evolution of the concept of Sinology in history, it critically analyzes some major ideas (...) of Sinologism in relation to Orientalism and draws the conclusion that the proponents of Sinologism are unaware of the inherent problems in Said’s theory and postmodern theory, have inadequate knowledge of Sinological history, and oversimplified the complex issues in Sinological studies. (shrink)

本书通过深入探究边沁法理学终极的哲学根据及其思想渊源而发现,在认识论上,边沁与贝克莱和休谟是一脉相承的,都秉持主观主义认识论,哈特所谓的道德中立在边沁法理学那里是根本不存在的.哈特的法律与道德是分离的 命题,最终依据的是G.E.摩尔所创立的认知与情感是分离的学说,而G.E.摩尔的分离学说乃是对休谟的"是—应当"区分学说的误解.

Prior studies on stakeholders’ responses to firms with high prior corporate social responsibility (CSR) engaging in corporate social irresponsibility (CSIR) show inconsistent results. To explore this inconsistency, we focus on the intentionality of CSIR and draw upon cognitive dissonance theory to examine how transgressional CSIR and accidental CSIR differently influence investors’ responses to firms with high prior CSR through both emotional (e.g., anger) and cognitive (e.g., moral judgment) processes. An experimental study using a facial expression analysis technology— FaceReader 5.0 (Study (...) 1) and a scenario experiment (Study 2), reveal that high prior CSR is a double-edged sword. Specifically, high prior CSR elicits an aggravating effect on investor responses (more anger, more negative moral judgment, and more negative effects on investment) in light of transgressional CSIR, but it has a buffering effect on investor responses (less anger, less negative moral judgment, and less negative effects on investment) in light of accidental CSIR. Moreover, we find that when prior CSR and CSIR are in the same (vs. different) domain, the aggravating effect of transgressional CSIR is strengthened, but the buffering effect of accidental CSIR is weakened. Our findings provide important theoretical and practical insights into the effect of prior CSR on investor responses in cases of different CSIR. (shrink)

Reductionism and complexity theory are two paradigms frequently found in language research. There exist a number of conflicts in terms of concepts and methodologies between reductionism and complexity theory, which are not conducive to creating a unified language research framework. This paper starts by discussing the adaptability of complex dynamic systems and combines cognitive processing model and artificial neural networks to construct and verify an adaptive weight model, showing that the study of reductionism is induction of high-weight elements and the (...) study of complexity theory is a discussion of system complexity from adaptability, meaning that there is a good fit between the two frameworks. The adaptive weight model is conducive to developing a unified interpretation of language research results. (shrink)

The late Ming monk Hanshan Deqing forced his way into a Buddhist service held around Wanli 10 to pray for the birth of the imperial heir. His action has long been seen as a heroic act that challenged the Wanli Emperor for the benefit of the state, yet an act that would lead to his exile later. However, this paper demonstrates that it was Deqing’s desperate but deliberate attempt to seek support from the inner court. This strategy helped Deqing to (...) rise to a leading Buddhist master in late Ming China, but it asked him to pay a high price by getting him involved in court strife. This paper reveals the fragility of the late Ming Buddhist revival under the pressure of contemporary politics. (shrink)

武汉大学优秀博士论文湖北省优秀博士论文湖北省教育厅社会科学研究“十五”规划重点项目武汉科技学院学科建设基金项目资助出版.

Robot manipulators have been extensively used in complex environments to complete diverse tasks. The teleoperation control based on human-like adaptivity in the robot manipulator is a growing and challenging field. This paper developed a disturbance-observer-based fuzzy control framework for a robot manipulator using an electromyography- driven neuromusculoskeletal model. The motion intention was estimated by the EMG-driven NMS model with EMG signals and joint angles from the user. The desired torque was transmitted into the desired velocity for the robot manipulator system (...) through an admittance filter. In the robot manipulator system, a fuzzy logic system, utilizing an integral Lyapunov function, was applied for robot manipulator systems subject to model uncertainties and external disturbances. To compensate for the external disturbances, fuzzy approximation errors, and nonlinear dynamics, a disturbance observer was integrated into the controller. The developed control algorithm was validated with a 2-DOFs robot manipulator in simulation. The results indicate the proposed control framework is effective and crucial for the applications in robot manipulator control. (shrink)

Career planning and career decision are important tasks for college students. The process may be affected by career stress, career exploration, and future work self, with some students facing career indecision. Combining both construction career and proactive motivation model, this study investigated the relationships between career stress, career exploration, future work self, career planning and career indecision among 1,012 Chinese college students using the Structure equation model to test the proposed mediation model. Results show that career stress negatively predicts career (...) planning, while career exploration positively predicts career planning. The mediating role of future work self has on career stress and career exploration's effects on both career planning and career indecision was verified. Moreover, the study also found future work self's positive effects on both career planning and career indecision in Chinese college students. Finally, the study's theoretical and practical significance and implications are discussed. (shrink)

This paper aims to develop the description of move systems in Systemic Functional Linguistics based on dynamism in knowledge exchanges, that is, the possible move options made available at different points in an exchange concerned with the negotiation of information. Using conversational interactions in Khorchin Mongolian as examples, the paper argues that at different points in a knowledge exchange, both the speaker and the addressee’s knowledge of the information are at stake. The speaker may be positioned either as knowing or (...) as not knowing the information; at the same time the addressee may be positioned either as knowing or as not knowing the information. It is also possible for the interlocutors not to be positioned either way. The move systems developed make it possible to discuss the options preselected and activated at different points in a knowledge exchange and the way interlocutors are dynamically positioned as an exchange unfolds. (shrink)