The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

Objective:The purpose of this study was to describe the current situation of moral distress and to explore its influencing factors among Chinese nurses.Methods:This is an exploratory, descriptive design study. A total of 465 clinical nurses from different departments in three Grade-III, Level-A hospitals in Jinan, Shandong Province, completed the questionnaires, including demographics questionnaire, Chinese version of Moral Distress Scale–Revised, and Job Diagnostic Survey.Ethical considerations:The study was approved by the university ethics board and the local health service director.Results:The total score of (...) Moral Distress Scale–Revised was 36.01 ± 24.02 points. The mean frequency and intensity scores of moral distress were 1.13 ± 0.49 and 1.09 ± 0.58, respectively. The level of moral distress among Chinese clinical nurses was low, and the frequency and intensity of moral distress were on low to moderate level. The level of moral distress experienced by clinical nurses is associated with demographics features and job characteristics, including age, education degree, department, task significance, autonomy, and dealing with others.Conclusion:Our conclusion suggests that hospital and organizational administrations should attach much importance to the moral distress experienced by clinical nurses in China. Further studies should focus on interventions about how to reduce the levels of the frequency and intensity of moral distress among clinical nurses. (shrink)

E. Husserl's reflections in Logical Investigations on "Intentional Feelings" and "non-intentional feelings" are significant in both his later ethical explorations and M. Scheler's thought on ethics. Through the incorporation of the views of Husserl and Scheler, we find that the phenomenology of the intentional feeling-acts is not only the foundation of the non-formal ethics of values in Scheler's phenomenology, but also at least the constitutive foundation of the ethics of Husserl's first orientation. /// 胡塞尔在 "逻辑研究" 中对 "意向感受" 和 "非意向感受" 的思考，无论是 (...) 在他后来的伦理学探讨中，还是在舍勒的伦理学思想中，都具有重要的意义。通过 将胡塞尔与舍勒的视域融合，可以发现，意向感受行为现象学不仅是舍勒现象学的 质料的价值伦理学基础，而且至少可以是胡塞尔第一个方向上的伦理学的建构基础。. (shrink)

This study draws on the substitutes for leadership theory to investigate the association of strengths-based leadership with employee turnover intention and the mediating role of felt obligation for constructive change and the moderating role of job control in the linkage. Data were collected using a three-wave survey from a sample of 317 employees working in a variety of enterprises in China. The multiple regression analyses with bootstrapping procedure were utilized to examine the proposed hypotheses. The results indicate that strengths-based leadership (...) negatively relates to turnover intention and felt obligation for constructive change partially mediates the relationship between strengths-based leadership and turnover intention. Furthermore, job control, acting as a substitute for strengths-based leadership, negatively moderates the indirect relationship between strengths-based leadership and turnover intention via felt obligation for constructive change. This study contributes to the literature of strengths-based leadership and the substitutes for leadership theory by enhancing our understanding of the effect of job control. (shrink)

This timely book offers revealing insights into the changing role of China in world governance as exemplified by the Silk Road Initiative, the People's Republic's first published major initiative for external affairs. Focusing on various aspects of the Silk Road Initiative, particularly those that are largely neglected in current discussions, including culture and philosophy, finance and investment, environmental protection and social responsibility, judiciary and lawyers, the authors explore a wide range of contexts in which China's role as an emerging power (...) in international relations and international law is examined. In the current era of ever-increasing populism, protectionism and challenges to globalization, the authors explore the Chinese philosophy underpinning Chinese norms of regional and international development. Bearing in mind the political and economic uncertainties hampering the establishment of such norms, the authors offer crucial insights into how the Silk Road Initiative could or should be developed and regulated. Given its depth of coverage, the book is an indispensable read for anyone interested in the Initiative and its social-legal implications. (shrink)

With the continuous development and improvement of Internet media technologies in China, the influence of livestream e-commerce is becoming increasingly prominent, and an increasing number of people are engaging in consumption activities in this field. It is important to study consumer stickiness in livestream e-commerce to promote economic structure adjustment and innovation-driven development. Therefore, in this study, we adopted the expectation confirmation theory as the theoretical framework and analyzed the ECT and stickiness. The study considered satisfaction as the previous influencing (...) factor of user and consumer stickiness, replaced the continuance intention in the expectation confirmation model with consumer stickiness as the explanatory variable, introduced the variable of perceived playfulness as the value perception after user experience, and established a consumer stickiness factors model. A total of 262 valid questionnaires were collected in this study, and SmartPLS analysis along with interviews were used to justify the limitations of data analysis. The results of the study demonstrated a significant effect of perceived usefulness and confirmation on satisfaction, a significant effect of confirmation on perceived usefulness, a significant effect of satisfaction on stickiness, and a significant effect of confirmation on perceived playfulness. Based on findings from the data analysis and interviews, we further proposed rationalized recommendations, and aimed to provide some theoretical guidance for future research on live streaming. (shrink)

The existing computer technology is used to conduct an in-depth study and analysis of drilling waste treatment, and the results are analyzed by computer simulation optimization algorithms. Based on the system theory, we define the research system, combine the unique characteristics of the technological innovation mechanism of drilling waste treatment, and use the internal and external factors affecting the technological innovation dynamics of drilling waste treatment, such as drilling waste treatment capacity, from the current actual situation. On this basis, factor (...) analysis is used to analyze the factors affecting technological innovation dynamics from both internal and external aspects of the system, establish a system model of technological innovation dynamics of drilling waste disposal, and give the initial values of the simulation model. This will reduce the pollution of the environment and enhance the competitiveness of enterprises. Drilling waste treatment technology is getting increased attention, but at this stage, there is no suitable technology innovation mechanism for drilling waste treatment. Through the simulation trend chart obtained by sensitivity analysis, the key factors in the system are found, and the innovation power mechanism of drilling waste treatment technology is constructed, which provides a basis for the formulation of enterprise technological innovation strategies and the development of technological innovation activities. Research on the dynamic mechanism of drilling waste treatment technology innovation explores a waste treatment mechanism suitable for the drilling industry, so as to promote the steady development of the drilling industry and at the same time provide theoretical support for the treatment of drilling engineering waste. (shrink)

In studying and researching Mao Zedong's philosophical thought, it is necessary not only to study the relationship between it and Marxist philosophy, but also to study its relationship to China's traditional philosophy.

Since the 1990s, grammatical complexity has received substantial research attention in applied linguistics. The representation of grammatical complexity has expanded in L2 writing with the application of diverse measures in empirical studies in the recent three decades. In response to this situation, we found it important to revisit grammatical complexity, and an exploratory factor analysis was applied to explore latent dimensions of grammatical complexity in L2 writing. We analyzed Lu’s 14 grammatical complexity measures in the L2 corpus of the British (...) Academic Written English Corpus. We then proposed a four-factor model with “clausal subordination,” “phrasal construction”, “global length unit” and “others.” The four factors generally align with the types of grammatical complexity proposed in Lu, but differences on six measures are also found. Noteworthy points were discussed to interpret the reasons behind the differences. Research implications are provided to show further research directions. (shrink)

The Affymetrix GeneChip is a popular microarray platform for genome‐wide expression profiling and has been widely used in functional genomics especially in the classification of cancers. Due to the updating of genome data, much of the genome information with which the chips were designed is out‐of‐date and it has been reported that many of the genes/transcripts on the chips differ from their original definition when mapping the probes to the new genome information. Dai et al. have reported that the updated (...) definition can cause as much as 30–50% discrepancy in the genes selected as differentially expressed on a heart tissue expression profiling dataset. Understanding the nature of this difference is therefore very important for the utilization of the data. In this work, with a large cancer dataset as an example, we compared two major definitions and investigated their effects on classification, clustering, discovery of differentially expressed genes and gene‐set‐based analysis. Results show that the two definitions agree well on clustering and classification results but genes and gene sets discovered as differentially expressed or enriched can be very different. Discoveries based on the Affymetrix definition can cover most of those based on the new definition, but tend to have more false positives. BioEssays 28: 739–746, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

In the intelligent transportation system, the license information can be automatically recognized by the computer and the vehicle can be tracked. Red light running, illegal change of lanes, vehicle retrograde, and other illegal driving events are reasonably recorded. This is undoubtedly an effective help for the traffic police to relieve the huge work pressure. However, in China, a considerable number of vehicle tracking methods have certain limitations in resisting complex external environmental influences. The external environmental factors include but not limited (...) to variable factors such as camera movement, jitter, and severe rain and snow. These factors cannot be controlled well, so the tracking accuracy is greatly reduced. In regard to this, this paper proposes an optimization method for moving vehicle tracking based on SPF. First, according to the size of the overlapping area of the motion area between the two images, the researcher can construct and simplify the vertex adjacency matrix that reflects the characteristics of the undirected bipartite graph. Then according to the corresponding relationship between the vertex adjacency matrix and the regional behavior and vehicle behavior, the researcher completes the regional behavior analysis and vehicle behavior analysis. On this basis, a particle filter vehicle tracking algorithm based on segmentation compensation is introduced, and the vector sum of the tracked segmentation area is used as the final position of the target vehicle. In this way, as many scattered particles fall on the target area as possible, which will greatly improve the efficiency of particle utilization, enhance tracking accuracy, and avoid the problem of tracking failure caused by too fast vehicle movement. Through experimental simulation, it can be seen that the method proposed in this paper can greatly enhance the vehicle tracking ability when tracking vehicles in “complex environments.”. (shrink)

Virtual reality provides an immersive 360-degree viewing experience and has been widely used in many areas. However, the transmission of panoramic video usually places a large demand on bandwidth; thus, it is difficult to ensure a reliable quality of experience under a limited bandwidth. In this paper, we propose a field-of-view prediction methodology based on limited FoV feedback that can fuse the heat map and FoV information to generate a user view. The former is obtained through saliency detection, while the (...) latter is extracted from some user perspectives randomly, and it contains the FoV information of all users. Then, we design a QoE-driven panoramic video streaming system with a client/server architecture, in which the server performs rate adaptation based on the bandwidth and the predicted FoV. We then formulate it as a nonlinear integer programming problem and propose an optimal algorithm that combines the Karush–Kuhn–Tucker conditions with the branch-and-bound method to solve this problem. Finally, we evaluate our system in a simulation environment, and the results show that the system performs better than the baseline. (shrink)

Previous studies have offered a rationale for engaging students in small-group student talk for the planning of L2 individual writing. To further investigate whether such talk effectively promotes the quality of argument in the context of Chinese tertiary EFL learners’ argumentative writing and whether such effects could be retained, the current study adopted a quasi-experimental design with a pretest, a posttest, and a delayed posttest in two intact EFL classes. The performance of the intervention group and the comparison group were (...) scrutinized to examine the effects of the intervention. The analytic scores on six components of the writing task and the holistic writing scores cumulated of all these components were measured to see the immediate and sustained effects. Significant changes of the holistic scores in both the immediate posttest and the delayed posttest indicated that such small-group student talk enabled students in the treatment class to achieve better performance in the overall quality of argumentation compared with those in the comparison class. Statistical analyses revealed immediate and sustained effects of small-group student talk on the quality of counterargument claim, counterargument data, and rebuttal claim. Counterargument claim was the only element in which students in both classes made significant improvement, but the treatment class demonstrated a larger effect size. No discernible differences were found either between or within the treatment class and the comparison class with respect to the quality of claim, data, and rebuttal data across tests. Possible explanations concerning the findings and limitations of the study were discussed. (shrink)

Objective: To investigate the correlation between preoperative response to the L-dopa challenge test and efficacy of deep brain stimulation (DBS) on motor function in Parkinson’s disease (PD).Methods: We retrospectively reviewed the data of 38 patients with idiopathic PD who underwent DBS surgery with a median follow-up duration of 7 months. Twenty underwent bilateral globus pallidus interna (GPi) DBS, and 18 underwent bilateral subthalamic nucleus (STN) DBS. The Movement Disorder Society Unified Parkinson Disease Rating Scale-Motor Part (MDS UPDRS-III) was assessed before (...) surgery and at the last follow-up in different medication and stimulation conditions, respectively.Results: Pearson’s correlation analysis revealed a positive correlation between preoperative L-dopa challenge responsiveness and GPi-DBS responsiveness on the total score (R2 = 0.283, p = 0.016) but not on the non-tremor total score (R2 = 0.158, p = 0.083) of MDS UPDRS-III. Such correlation remained significant (R2′ = 0.332, p = 0.010) after controlling for age at the time of surgery as confounding factor by partial correlation analysis. The preoperative L-dopa challenge responsiveness was significantly correlated with the tremor-controlling outcome of GPi-DBS (R2 = 0.390, p = 0.003). In contrast, we found a positive correlation between preoperative L-dopa challenge responsiveness and STN-DBS responsiveness on the non-tremor total score (R2 = 0.290, p = 0.021), but not on the total score (R2 = 0.130, p = 0.141) of MDS UPDRS-III. The partial correlation analysis further demonstrated that the predictive value of preoperative L-dopa challenge responsiveness on the non-tremor motor outcome of STN-DBS was eliminated (R2′ = 0.120, p = 0.174) after controlling for age at the time of surgery as confounding factor.Interpretation: The short-term predictive value of preoperative response to the L-dopa challenge test for the motor outcome of GPi-DBS in PD was systematically described. Our findings suggest: (1) a solid therapeutic effect of GPi-DBS in treating L-dopa-responsive tremors; (2) a negative effect of age at the time of surgery on motor outcomes of STN-DBS, (3) a possible preference of STN- to GPi-DBS in L-dopa-resistant tremor control, and (4) a possible preference of GPi- to STN-DBS in elderly PD patients who have a satisfactory dopamine response. (shrink)

The Biliu River is the largest river in Dalian. The occurrence of floods and droughts in this basin has extremely important impacts on local industry, agriculture, and urban development. For a long time, the annual distribution of precipitation in the Biliu River Basin is extremely uneven, the river runoff varies greatly from year to year and season to year, floods and droughts occur frequently, and serious soil erosion results in fragile ecological environment and severe shortage of water resources. In this (...) paper, the spatial and temporal changes of rainfall and runoff in the Biliu River Basin are studied through the coupling of the MIKE 11 model and the MIKE SHE model. The hydrological changes in the Biliu River Basin are simulated. The coupled model is verified by monthly runoff data from 1996 to 2015, and the simulation values are found to be true. The values match well. Based on the cyclical pattern of precipitation and runoff in the Biliu River Basin, the rainfall and runoff data in the Biliu River Basin from 2016 to 2030 are derived. The MIKE SHE/MIKE 11 coupling model is used to predict the Biliu River from 2016 to 2030. The results show that flood disasters are expected to occur in August 2020, July 2025, and July 2030, which can provide a basis for hydrological management in the Biliu River Basin. (shrink)

Based on 2010 to 2019 Chinese outward foreign direct investment panel data from 39 host countries, this paper studies the relationships between host country cultural characteristics and Chinese OFDI. The OLS regression results show that the cultural tolerance and trust in the host countries are significantly positively correlated with Chinese OFDI, which are robust according to the system GMM tests. Further analysis reveals that cultural tolerance is more positively related to Chinese OFDI in host countries with higher legislation and economic (...) freedom, while cultural trust is positively associated with Chinese OFDI in host countries with lower legislation and economic freedom. In addition, higher cultural tolerance and trust promote Chinese OFDI in countries with greater cultural distance. Unlike traditional studies based on cultural distance in international trade, using more representative cultural characteristics, this paper provides references to Chinese OFDI decision-making based on the root characteristics associated with heterogeneous cultural influences. (shrink)

Pellet is widely used in blast furnace ironmaking. Pellet quality affects the effect of ironmaking, the existing control system of grating-rotary kiln mainly adopts manual control mode, and the quality of pellet production largely depends on the experience, fatigue, and sense of responsibility of the site operators. The use of the Internet of things technology in the integration and improvement of enterprise information level, to achieve fine, intelligent production management, at the same time, is conducive to promoting steel enterprises to (...) reduce costs and increase efficiency, energy conservation and emission reduction, transformation and upgrading, and taking a new road to industrialization. According to the working principle and technological characteristics of the grate-rotary kiln at all stages, this paper designs the management system of firing pellets based on convolutional neural network and IoT technology, so as to realize automatic recognition of image data obtained by the perceptual layer and make an intelligent analysis of it. The system can classify the working conditions of the current equipment, so as to judge whether the production process parameters of the grate-rotary kiln are up to the standard, thus achieving the goal of controlling the quality of the finished pellet. (shrink)

Computational social science, as an emerging interdisciplinary discipline, is a field ushered in by long-term development of traditional social science. It is committed to supplying data thinking, resources, and analytics to study human social behavior and social operation laws to accurately grasp and judge the developing path of the discipline, which is of great significance to promote the innovation and development of social sciences. This study is to conduct a systematic quantitative analysis from a bibliometric perspective, aiming to provide a (...) reference for scholars to explore the paths and changing rules in the field. We use the relevant literature in Web of Science as the dataset. After eliminating journal calls and irrelevant literature, R language and SciMAT tools are used to visualize and analyze the number of articles, keyword clustering, keyword cooccurrence network, and theme evolution, so as to summarize and sort out the paths of computational social science research. The study found that the annual volume of publications has been gradually increasing and will probably remain active in the next few years with high productivity. Subject themes in different periods are diversified, and the evolutionary relationship is found complex as well. Besides, as a cross discipline, scientific knowledge from different fields cross collides and couples with each other in the big data environment, changing the traditional concept of computational social science and forming a new development path. Recently, the emergence of “big data+” has promoted the rise of new subject areas, making the development of new disciplines a reality. (shrink)

Extant literature has underlined the importance of newcomer proactive socialization to the organization. However, the effect of coworker ostracism on newcomers’ proactive behaviors has not been noticed. Drawing on the conservation of resources theory, we proposed a model exploring how coworker ostracism impacted newcomers’ proactive behaviors via the mediation of psychological availability. Through an empirical study with a sample of 263 newcomers and three waves of longitudinal data, we found that coworker ostracism had a negative effect on newcomers’ information seeking (...) and guanxi developing. In addition, emotional intelligence enhanced the negative effect of coworker ostracism on newcomers’ psychological availability and the indirect influence of coworker ostracism on newcomers’ proactive behaviors via psychological availability. Important theoretical and practical implications are discussed. (shrink)

[full article, abstract in English; abstract in Lithuanian] Modern revolution as the beginning of founding a new political order has to confront the vicious circle inhered in all beginnings: in so far as it is the beginning, where does its principle come from? Or, if there is no principle, how could the beginning establish one? Set in the context of modern political experience, the aporia is equal to the problem of how modern politics to be self-grounded or how to reestablish (...) political authority in modernity? By an exploration into the relevant writings of Hannah Arendt, the article tries to investigate the vicious circle of beginning and principle in the political realm, and to point out that Arendt has told a story about the mutual generating of beginning and principle, turning the so-called vicious circle into a hermeneutic circle, in which those implicit principles become explicit through the performance of founding actions. (shrink)

本书运用了伦理学、教育学、心理学等学科,论述了道德的概念、功能、教师职业道德的内容、规范及自我修养等。.

Ben shu shi zuo zhe cong du shu bi ji zhong xie qu de yi zu san wen sui bi, fan ying le zuo zhe zai yi shu he zhe xue shang de tan suo yu zhui qiu.

本書分上下兩篇:上篇為"孔子的公天下之夢",主要介紹孔子一生的夢想--天下為公,著重闡述孔子積極推行"仁愛"來實現公天下的大同世界,並從各個方面介紹孔子的一生.下篇為"中國家天下的歷史",以孔子的觀點 ,從伏羲到溥儀,將中國歷史分為"公天下"和"家天下"兩個歷史時期,用大量史實闡明公天下的領導人一心為人民謀福祉,受到百姓的擁護;而家天下的帝王則據天下為己有,窮凶極惡地壓迫,剝削人民,是人隊民的死對頭 ,最終遭到民眾的唾棄.

本书采用一图配一文的方式,用白话简明扼要地介绍了孔子及七十二弟子的言行事迹、身份、成就等。.

Detailed summary in vernacular field only.