Since its inception in the Middle Ages, the university classroom can be characterized by students gathered around a sage who imparts his or her knowledge. However, the effective classroom of today looks vastly different: First-year engineering students not only learn basic engineering principles, but are also guided to consider their own inner values and motivations as they design and build adaptive devices for people with disabilities; students in a large chemistry lecture work animatedly together in small groups on inquiry-based activities (...) while an instructor and teaching assistants circulate and guide their learning; students learning differential equations practice explicit metacognitive skills while problem-solving in class. Even though educational research, especially research that is targeted at STEM disciplines, demonstrates what most effectively engages students and supports their learning, many of today's classrooms look much like they did a century ago, with a professor delivering a primarily one-way lecture and students passively sitting in seats bolted to the floor. At this juncture in history, colleges and universities face a public call to engage a more diverse representation of students in effective learning, persistence, and degree attainment, and to do so economically and efficiently. It is essential that institutions draw upon methods demonstrated to effectively increase student learning and success. Educational researchers have thoroughly explored the "basic" science in this area, and a body of literature documents effective evidence-based instructional practices, hereafter referred to as EBIPs. (shrink)

Isolation in the back-country: George Chamier, G.B. Lancaster, Katherine Mansfield, John Mulgan, and Graham Billing -- Outsiders and misfits in fragmented social milieux: William Satchell, Vincent Pyke, John A. Lee, Robin Hyde, Frank Sargeson, and others -- The lonely and the alone in the fiction of Janet Frame -- Maurice Gee and postmodern isolation -- Women, isolation, and history: Fiona Kidman, Noel Hilliard, and Patricia Grace -- Cultural deracination and isolation : Witi Ihimaera, Keri Hulme, and Alan Duff.

This paper argues that Aristotelian practical wisdom (phronêsis) is a state of conviction (pistis) in the goodness of our goals based on proper grounds. This state of conviction can only be achieved if rational arguments and principles agree with how things appear to us. Since, for Aristotle, passions influence appearances, they can support or undermine our conviction in the goodness of ends that are worth pursuing. For this reason, we cannot be practically wise without virtuous dispositions to experience appropriate passions. (...) Along the way, I argue that this reading allows us to explain the shortcomings of self-controlled and akratic agents. -/- . (shrink)

Taking the lead from Susan Wolf's and Linda Emanuel's work on systems thinking, and developing ideas from Moberg's, Seabright's and my work on mental models and moral imagination, in this paper I shall argue that what is often missing in management decision-making is a systems approach. Systems thinking requires conceiving of management dilemmas as arising from within a system with interdependent elements, subsystems, and networks of relationships and patterns of interaction. Taking a systems approach and coupling it with moral imagination, (...) now engaged on the organizational and systemic as well as individual levels of decision-making, I shall conclude, is a methodology that encourages managers and companies to think more imaginatively and to engage in integrating moral decision-making into ordinary business decisions. More importantly this sort of thinking is a means to circumvent what often appear to be intractable problems created by systemic constraints for which no individual appears to be responsible. (shrink)

Evolutionary biology and feminism share a variety of philosophical and practical concerns. I have tried to describe how a perspective from both evolutionary biology and feminism can accelerate the achievement of goals for both feminists and evolutionary biologists. In an early section of this paper I discuss the importance of variation to the disciplines of evolutionary biology and feminism. In the section entitled “Control of Female Reproduction” I demonstrate how insight provided by participation in life as woman and also as (...) a feminist suggests testable hypotheses about the evolution of social behavior—hypotheses that are applicable to our investigations of the evolution of social behavior in nonhuman animals. In the section on “Deceit, Self-deception, and Patriarchal Reversals” I have overtly conceded that evolutionary biology, a scientific discipline, also represents a human cultural practice that, like other human cultural practices, may in parts and at times be characterized by deceit and self-deception. In the section on “Femininity” I have indicated how questions cast and answered and hypotheses tested from an evolutionary perspective can serve women and men struggling with sexist oppression. (shrink)

In this dissertation, I argue that Heidegger offers a philosophy of science by explicating that philosophy of science. The following chapter presents Heidegger's early analysis of modern science, from 1916 to the mid-1930s. During these years Heidegger maintains two theses: that the essence of science is the mathematical projection of nature; and that metaphysics is the science of being. As the latter thesis becomes more problematic, Heidegger turns from metaphysics as a science, to the sciences. ;The pivot for this turn (...) is the experiment. Chapter 3 is an analysis of three specific issues surrounding the experiment. I raise the question of whether a single experimental result is enough to overturn a theory, the problem of the theory-loadedness of observation, and the question of representation. ;These issues serve to explicate Heidegger's claim that the essence of science is research, and to show that Heidegger's philosophy of science shares issues with contemporary analytic philosophy of science. Further, I take Heidegger's claim that the essence of science is the ground from out of which the essence of the modern epoch can be shown, as proof that his consideration of science is not secondary in his thinking but rather is the basis from which his critique of the modern epoch is made. ;Chapter 4 is an account of Heidegger's view of the role of science in the university. Heidegger's vision is that the German university can serve to guide historical destiny. His complete disillusionment with that vision comes with his realization that, whereas he calls for a renewal of science for the sake of the sciences in their service of the people, the Nazi call for a renewal of the sciences is toward their own political ends. What little I have to say about Heidegger's involvement with the Nazis is found in this chapter. ;Chapter 5 considers Heidegger's view of ancient science. It lays out Aristotle's distinction between physis and techne under Heidegger's reading. In Chapter 6, I argue that the ancient distinction between physis and techne is not sustained in the modern epoch under Heidegger's account. ;I close with a brief account of Heidegger on quantum theory. (shrink)

This paper argues that Aristotelian thumos is a non-reducible mental phenomenon that plays a central role in Aristotle’s theory of the mind, motivation, and action. For Aristotle, thumos is not primarily, as others have argued, a desire for the noble, social appraisal, or retaliation; rather, it is an inner drive or impulse to act. More precisely, it is an executory urge to implement or enact one’s ends or goals, whatever they are. Thumos accounts for someone’s proneness to spring into action (...) and can contribute to bringing about rational or non-rational, first-order desires. It is a second-order motivation, which both human and non-human animals have and that comes in degrees: we can be more or less thumotic, which amounts to being more or less disposed to making first-order desires effective so that they issue in actions. Aristotelian thumos, then, anticipates features of the modern notion of the will. Along the way, I argue that thumos is key to Aristotle’s efforts to differentiate and hierarchically organize species, characters, genders, and peoples. (shrink)

Hegel’s interpretation of Sophocles’ play Antigone is central to an understanding of woman’s role in the Hegelian system. Hegel is fascinated by this play and uses it in both the Phenomenology and the Philosophy of Right to demonstrate that familial ethical life is woman’s unique responsibility. Antigone is revealed as the paradigmatic figure of womanhood and family life in both the pagan and modern worlds although there are fundamental differences between these two worlds for Hegel. In order to situate the (...) interpretation of this play within its wider context I shall begin with a brief outline of the pagan world described in the Phenomenology. I will then consider the interpretation of this play within the analysis of the modern world in the Philosophy of Right. Throughout, the focus will be on woman’s role in Hegel’s philosophy. (shrink)

Studies on informed consent to medical research conducted in low or middle-income settings have increased, including empirical investigations of consent to genetic research. We investigated voluntary participation and comprehension of informed consent among women involved in a genetic epidemiological study on breast cancer in an urban setting of Nigeria comparing women in the case and control groups.

We investigated the role of honour concerns in mediating the effect of nationality and gender on the reported intensity of anger and shame in reaction to insult vignettes. Spain, an honour culture, and The Netherlands, where honour is of less central significance, were selected for comparison. A total of 260 (125 Dutch, 135 Spanish) persons participated in the research. Participants completed a measure of honour concerns and answered questions about emotional reactions of anger and shame to vignettes depicting insults in (...) which type of threat was manipulated. It was found that Spanish participants responded especially intensely to insults that threaten family honour, and that this effect of nationality on emotional reactions to threats to family honour was mediated by individual differences in concern for family honour. (shrink)

Habit and Embodiment in Merleau-PontyIntroductionMerleau-Ponty (French phenomenological philosopher, born in 1908 and deceased in 1961) refers to habit in various passages of his Phenomenology of Perception as a relevant issue in his philosophical and phenomenological position. Through his exploration of this issue he explains both the pre-reflexive character that our original linkage with the world has, as well as the kind of “understanding” that our body develops with regard to the world. These two characteristics of human existence bear a close (...) relation with the vision of an embodied mind sustained by Gallagher and Zahavi in their work The Phenomenological Mind: An Introduction to Philosophy of Mind and Cognitive Science. Merleau-Ponty uses concepts like those of the lived or own body and of lived space in order to emphasize, from a first-person perspective, the co-penetration that exists between subject and world.Gallagher and Zahavi have regained the experience of phenomenology, especially that of Merleau-Ponty and Sartre, to contribute to the development of the cognitive sciences. Via the phenomenological approach to the reality of habit, a new understanding of the body becomes possible for us, such that it becomes characterized “as subject, as experiencer, as agent”, and at the same time we can understand “the way the body structures our experience” (Gallagher and Zahavi, 2008). Additionally, the idea of a pre-reflexive understanding is conceived of by these authors... (shrink)

It is now a platitude that sexual objectification is wrong. As is often pointed out, however, some objectification seems morally permissible and even quite appealing—as when lovers are so inflamed by passion that they temporarily fail to attend to the complexity and humanity of their partners. Some, such as Nussbaum, have argued that what renders objectification benign is the right sort of relationship between the participants; symmetry, mutuality, and intimacy render objectification less troubling. On this line of thought, pornography, prostitution, (...) and some kinds of casual sex are inherently morally suspect. I argue against this view: what matters is simply respect for autonomy, and whether the objectification is consensual. Intimacy, I explain, can make objectification more morally worrisome rather than less, and symmetry and mutuality are not relevant. The proper political and social context, however, is crucial, since only in its presence can consent be genuine. I defend the consent account against the objection that there is something paradoxical in consenting to objectification, and I conclude that given the right background conditions, there is nothing wrong with anonymous, one-sided, or just-for-pleasure kinds of sexual objectification. (shrink)

There are important synergies for the next generation of ethical leaders based on the alignment of modified or adjusted mental models. This entails a synergistic application of moral imagination through collaborative input and critique, rather than "me too" obedience. In this article, we will analyze the Milgram results using frameworks relating to mental models (Werhane et al., Profitable partnerships for poverty alleviation, 2009), as well as work by Moberg on "ethics blind spots'' (Organizational Studies 27(3): 413-428, 2006), and by Bazerman (...) and Chugh on "bounded awareness" (Harvard Business Review, 2006; Mind & Society 6: 1-18, 2007) Using these constructs to examine the Milgram experiment, we will argue that the ways in which the experiments are framed, the presence of an authority figure, the appeal to the authority of science, and the situation in which the naïve participant finds herself or himself, all create a bounded awareness, a narrow blind spot that encourages a climate for obedience, brackets out the opportunity to ask the moral question: "Am I hurting another fellow human being?" and may preclude the subject from utilizing moral imagination to opt out of the experiment. We will conclude that these forms of almost blind obedience to authority are correctable, but with difficulty. We will argue that linking the modification of mental models to an unbinding of awareness represents an important synergistic relationship and one that can build effectively on the lessons learned from our experience with moral imagination. (shrink)

No presente ensaio, discute-se o impacto do negacionismo na Educação escolar. Essa ideologia é baseada em falsos argumentos, cujos protagonistas negam evidências cientificamente comprovadas, como forma de fortalecer seus anseios pelo poder. A narrativa negacionista atinge pessoas que aceitam acriticamente e replicam esses argumentos como se fossem verdades absolutas. Um dos resultados da disseminação e aceitação dessa ideologia é o estímulo a ações extremistas, como vimos acontecer recentemente no Brasil. A negação fomenta intencionalmente os analfabetismos histórico, social e científico. As (...) pessoas "contaminadas" por essa ideologia extremista ignoram os argumentos lógicos e permanecem alheias ao avanço da Ciência. Acreditam em disparates, como o chamado “terraplanismo”; são disseminadores de informações falsas; promovem “cruzadas” antivacinação; defendem o uso de medicamentos ineficazes; e fomentam o descrédito da democracia. As ideias de Paulo Freire, que estimulam o cultivo do pensamento crítico e emancipatório, é o aporte teóricometodológico que norteia este ensaio, contextualizado na prática docente dos autores, que consideram a Educação como uma prática de liberdade. (shrink)

In this article, we attempt to shed light on how, placed by the law in a situation of identity suspension that is "impossible to bear," unaccompanied minors (UAMs) can construct themselves, caught as they are between a unique personal identity that they know they must mourn in order to be able to stay in the territory, and a projected identity, also constructed by and within the fantasy of the Other. In this context, we consider the possible scope for a relationship (...) between UAMs and social workers or volunteers, and how the understanding of the topology of the Borromean knot can be used in the training of social workers and volunteers. (shrink)

We describe and analyze 13 cases handled by our ethics consultation service (ECS) in which families requested continuation of physiological support for loved ones after death by neurological criteria (DNC) had been declared. These ethics consultations took place between 2005 and 2013. Patients’ ages ranged from 14 to 85. Continued mechanical ventilation was the focal intervention sought by all families. The ECS’s advice and recommendations generally promoted “reasonable accommodation” of the requests, balancing compassion for grieving families with other ethical and (...) moral concerns such as stewardship of resources, professional integrity, and moral distress. In cases we characterized as finitegoal accommodation, a “reasonable accommodation” strategy proved effective in balancing stakeholders’ interests and goals, enabling steady progress toward resolution. When a family objected outright to a declaration of DNC and asked for an indefinite accommodation, the “reasonable accommodation” approach offered clinicians little practical direction, and resolution required definitive action by either the family or the clinical team. Based on our analysis and reflections on these 13 cases, we propose ethically justified and practical guidelines to assist healthcare professionals, administrators, and ECSs faced with similar cases. (shrink)

Building on the virtues that made the first edition of _A Presocratics Reader_ the most widely used sourcebook for the study of the Presocratics and Sophists, the second edition offers even more value and a wider selection of fragments from these philosophical predecessors and contemporaries of Socrates. With revised introductions, annotations, suggestions for further reading, and more, the second edition draws on the wealth of new scholarship published on these fascinating thinkers over the past decade or more, a remarkably rich (...) period in Presocratic studies. At the volume's core, as ever, are the fragments themselves--but now in thoroughly revised and, in some cases, new translations by Richard D. McKirahan and Patricia Curd, among them those of the recently published Derveni Papyrus. (shrink)

This important book proposes a new account of the nature of language, founded upon an original interpretation of Wittgenstein. The authors deny the existence of a direct referential relationship between words and things. Rather, the link between language and world is a two-stage one, in which meaning is used and in which a natural language should be understood as fundamentally a collection of socially devised and maintained practices. Arguing against the philosophical mainstream descending from Frege and Russell to Quine, Davidson, (...) Dummett, McDowell, Evans, Putnam, Kripke and others, the authors demonstrate that discarding the notion of reference does not entail relativism or semantic nihilism. A provocative re-examination of the interrelations of language and social practice, this book will interest not only philosophers of language but also linguists, psycholinguists, students of communication and all those concerned with the nature and acquisition of human linguistic capacities. (shrink)

Building on Deleuze’s theories of the becoming of bodies, and notions of the geographic maturity of the disabled body we formulate an emplaced model of disability wherein bodies, social expectations and built form intersect in embodied experiences in specific environments to increase or decrease the capacity of disabled children to act in those environments. We join a growing effort to generate a more comprehensive model of disability, which moves beyond a binary between the individual and the social. Drawing on in-depth (...) case studies conducted with 13 physically disabled children, we consider the intersections between their primary environments (homes, schools and neighbourhoods) and the multiple subjectivities they embody. Ultimately we make a case about the importance of responsive, situated models of subjectivity for the development of adaptations, and that physical and social adaptations must respond to these children’s complex and varied needs and desires. (shrink)

Marx's Critique of Hegel's Philosophy of Right (1843) makes the very case for Democracy as a privileged constitutional form that he makes in the 1844 Manuscripts for communism. Democracy is the "generic constitution" to which monarchy stands as a species. Democracy is "content and form", since the state is essentially the Demos and Democracy is goverment of the People. "Democracy is the resolved mystery of all constitutions".

Currently, Nursing Education draws on a commonly taken‐for‐granted folk psychology of a representational view of how the mind works and how human beings learn. Descartes' representational view of the mind strongly influences pedagogies, theories of learning, curricula, and approaches to testing nursing knowledge and more broadly in academia. A representational view of the mind holds that perception occurs in the mind only through representations in the mind through ideas, concepts, templates and schema. Situated, embodied, and socially embedded cognition is presented (...) as a counter view to a representational view of the mind. (shrink)

In this paper we set out to explore the claims that corporate social responsibility (CSR) itself is little more than a complementary extension of the project of coloniality initiated by the Enlightenment (e.g. Banerjee 2019). We will not dispute that claim. Rather we will develop three points. First, we will apply a non-linear, systems approach to demonstrate how we all, of any color, ethnic origin or historical location are all part of an interconnected interrelated sets of systems—what some thinkers call (...) a complex adaptive system or systems (e.g., Miller and Page 2007) so that dismissing or degrading any particular ethnic, gender, or racial group is dismissing part of our history and origin. Secondly, we will argue that Enlightenment, coloniality, as well as neo-coloniality, and decoloniality sprung up from the Enlightenment projects themselves. Thus, the very critiques of Enlightenment, accurate as they may be, evolved from that perspective and have to be taken into account even in those critiques. Third, what appears to be an “either-or” – that is, that commerce should stick to business and not engage in political activities (forms of neocolonialism) or accept these business-political activities despite critiques – is not a simple choice. Rather, conceding that commerce and political systems cannot be nicely separated, we will provide some principles or ways to evaluate these activities, seemingly ubiquitous particularly in emerging economies. (shrink)

BioPortal is a Web portal that provides access to a library of biomedical ontologies and terminologies developed in OWL, RDF(S), OBO format, Protégé frames, and Rich Release Format. BioPortal functionality, driven by a service-oriented architecture, includes the ability to browse, search and visualize ontologies (Figure 1). The Web interface also facilitates community-based participation in the evaluation and evolution of ontology content.

In this paper, I claim that the doctor-patient relationship can be viewed as a vessel of trust. Nonetheless, trust within the doctor-patient relationship has been impaired by managed care. When we conceive of trust as social capital, focusing on the role that it plays in individual and social well-being, trust can be viewed as a public good and a scarce medical resource. Given this, there is a moral obligation to protect the doctor-patient relationship from the cost-containment mechanisms that compromise its (...) ability to produce trust. (shrink)

Among the paradoxical aspects of Hobbes's scepticism attention has recently turned to Hobbes's fool of Leviathan , chapter xv, where Hobbes makes a claim about justice that paraphrases Psalm 52:1: "The fool hath said in his heart there is no God." It is a charge of which Hobbes himself could be suspected, but in fact we see that it is on this startling claim that his legal positivism rests. Moreover it is embedded in a theory of natural law that Hobbes (...) inherited from the late scholastics and that he shares in common with Grotius as a practical solution to the problem of scepticism. Indeed, the fool is not even honoured with the designation "sceptic." He is simply dumb, stultus , one of the mindless mob, or those led astray by priests. Hobbes's treatment of the fool as stultus is Epicurean, as we see in the Historia Ecclesiastica , where he gives the topos special attention, and Epicureanism helps us solve the puzzle of the fool. (shrink)

This Companion makes a new departure in Hobbes scholarship, addressing a philosopher whose impact was as great on Continental European theories of state and legal systems as it was at home. This volume is a systematic attempt to incorporate work from both the Anglophone and Continental traditions, bringing together newly commissioned work by scholars from ten different countries in a topic-by-topic sequence of essays that follows the structure of Leviathan, re-examining the relationship among Hobbes's physics, metaphysics, politics, psychology, and religion. (...) Collectively they showcase important revisionist scholarship that re-examines both the context for Leviathan and its reception, demonstrating the degree to which Hobbes was indebted to the long tradition of European humanist thought. This Cambridge Companion shows that Hobbes's legacy was never lost and that he belongs to a tradition of reflection on political theory and governance that is still alive, both in Europe and in the diaspora. (shrink)

Abstract:This essay suggests that the word decolonial offers analytic power for feminist historians of women. As a category, it creates interpretive space for female experience beyond the elite/subaltern binary, where arguably most women live and work in the modern period. As a reading practice, the decolonial fosters intellectual awareness of social and intellectual practices that neither address the state, as in “anti-imperialism,” nor proffer counter nationalism or counter racialization as responses to coloniality. Offering examples from the archive, the media, and (...) teaching, this essay describes the decolonial as a productive site of women's agency in domains all too easily overlooked when historians focus on the conventional categories of state and nation. (shrink)

The dominant view of the status of knowledge of language is that it is theoretical or what Gilbert Ryle called knowledge-that. Defenders of this thesis may differ among themselves over the precise nature of the knowledge which underlies language, as for example, Michael Dummett and Noam Chomsky differ over the issue of unconscious knowledge; however, they all agree that acquisition, understanding and use of language require that the speaker have access to a theory of language. In this paper, I argue (...) that this view is mistaken. Knowledge of language is properly seen as practical knowledge, knowledge-how. My target is Michael Dummett’s treatment of theory of meaning in The Seas of Language. If my argument goes through, underlying assumptions about the nature of cognition as computational must be adjusted to allow for other forms of knowledge, which are arguably more basic, and which underlie knowledge-that. (shrink)

Innate emotional bases of ethics have been proposed by authors in evolutionary psychology, following Darwin and his sources in eighteenth-century moral philosophy. Philosophers often tend to view such theories as irrelevant to, or even as tending to undermine, the project of moral philosophy. But the importance of emotions to early moral learning gives them a role to play in determining the content of morality. I argue, first, that research on neural circuits indicates that the basic elements or components of emotions (...) need not be limited to what psychologists think of as basic emotions. But in that case, innate mechanisms of social transfer of emotion, such as infants’ tendency to facial imitation, gaze-following, and emotional contagion or empathy, provide a source of plasticity in developing the basic elements that lets emotions incorporate cultural influence from early on. This leaves room later for cognitive components of adult human emotions and hence for the further role of language in conveying cultural influence. We can thus see how moral judgment might depend on innate emotional capacities that are both modifiable by culture and capable of registering objective values. I use Rawls’s treatment of the development of moral sentiments to illustrate the kind of supportive role that emotions can play in a principle-based account – though my own account involves modifications I go on to indicate. (shrink)

While Martin Buber is best known for his conception of the so-called I-Thou relation, many of his philosophical writings are concerned with the wider realities of communal being together. The aim of this paper is to examine this largely neglected aspect of Buber’s work by focusing on the concept of the “essential We”. As I will argue in this paper, this concept did not develop in a philosophical vacuum, but in critical dialogue with pre-eminent thinkers of the phenomenological tradition. Contra (...) Heidegger, Buber defends the claim that the We must be explored via an investigation of dyadic I-Thou relations. As I further demonstrate, this idea coincides in many respects with Husserl’s approach towards the We, although both conceptualize the I-Thou relation in different ways. While Husserl conceives of the relation between an I and a you as one that foregrounds the similarities between self and other and thereby allows one to adopt a common we-perspective, Buber celebrates the I-Thou relation’s ability to make visible the other person’s particularity and otherness. However, instead of putting these different accounts into competition, I argue that both highlight important features of two distinct forms of group alignment considered in recent social psychology. (shrink)

Resumo O objetivo deste artigo é interpretar o livro Dialética do esclarecimento e seus principais argumentos, considerando a dominação masculina que perpassa a racionalidade moderna. Para isso, sugere-se uma interpretação acerca do entrelaçamento entre mito e esclarecimento, durante o processo de civilização ocidental, indicando que os argumentos de Adorno e Horkheimer tomam a modernidade como um projeto fundamentalmente masculino.This article aims to interpret the book Dialectic of Enlightenment and its main arguments considering the masculine domination which permeates the modern rationality. (...) In order to do this an interpretation about the intertwining between myth and enlightenment during the process of western civilization is suggested, indicating that the arguments of Adorno and Horkheimer take modernity as a fundamentally male project. (shrink)

This special issue of Etikk i praksis - Nordic Journal of Applied Ethics deals with the largely underexplored connections between public domain and democracy in the digital age and features articles highlighting various aspects of this broader theme.

Sex determination offers an opportunity to address many classic questions of developmental biology. In addition, because sex determination evolves rapidly, it offers an opportunity to investigate the evolution of genetic hierarchies. Sex determination in Drosophila melanogaster is controlled by the master regulatory gene, Sex lethal (Sxl). DmSxl controls the alternative splicing of a downstream gene, transformer (tra), which acts with tra2 to control alternative splicing of doublesex (dsx). DmSxl also controls its own splicing, creating an autoregulatory feedback loop that ensures (...) expression of Sxl in females, but not males. A recent paper1 has shown that in the dipteran Ceratitis capitata later (downstream) steps in the regulatory hierarchy are conserved, while earlier (upstream) steps are not. Cctra is regulated by alternative splicing and apparently controls the alternative splicing of Ccdsx. However, Cctra is not regulated by CcSxl. Instead it appears to autoregulate in a manner similar to the autoregulation seen with DmSxl. BioEssays 25:1–4, 2003. © 2002 Wiley Periodicals, Inc. (shrink)

The language of evolutionary biology and psychology is built on concepts applicable in the first instance to individual strategic rationality but extended to the level of genetic explanation. Current discussions of mental disorders as evolutionary adaptations would apply that extended language back to the individual level, with potentially problematic moral/political implications as well as possibilities of confusion. This paper focuses on one particularly problematic area: the explanation of women's greater tendency to depression. The suggestion that there are "good evolutionary reasons" (...) for depression makes sense, and might be helpful to note in therapy, as implying that the tendency is not a defect. However, evolutionary adaptiveness should not be confused with individual or psychological adaptiveness. Besides making reference to an earlier environment, it presupposes a strategic standpoint that may not accord with the legitimate interests of the individual, as this example makes vivid. (shrink)