The National Center for Biomedical Ontology is a consortium that comprises leading informaticians, biologists, clinicians, and ontologists, funded by the National Institutes of Health (NIH) Roadmap, to develop innovative technology and methods that allow scientists to record, manage, and disseminate biomedical information and knowledge in machine-processable form. The goals of the Center are (1) to help unify the divergent and isolated efforts in ontology development by promoting high quality open-source, standards-based tools to create, manage, and use ontologies, (2) to create (...) new software tools so that scientists can use ontologies to annotate and analyze biomedical data, (3) to provide a national resource for the ongoing evaluation, integration, and evolution of biomedical ontologies and associated tools and theories in the context of driving biomedical projects (DBPs), and (4) to disseminate the tools and resources of the Center and to identify, evaluate, and communicate best practices of ontology development to the biomedical community. Through the research activities within the Center, collaborations with the DBPs, and interactions with the biomedical community, our goal is to help scientists to work more effectively in the e-science paradigm, enhancing experiment design, experiment execution, data analysis, information synthesis, hypothesis generation and testing, and understand human disease. (shrink)

BioPortal is a Web portal that provides access to a library of biomedical ontologies and terminologies developed in OWL, RDF(S), OBO format, Protégé frames, and Rich Release Format. BioPortal functionality, driven by a service-oriented architecture, includes the ability to browse, search and visualize ontologies (Figure 1). The Web interface also facilitates community-based participation in the evaluation and evolution of ontology content.

This Element provides an opinionated introduction to the debate in moral philosophy over identifying the basic elements of well-being and to the related debate over the nature of happiness. The question of the nature of happiness is simply the question of what happiness is, and the central philosophical question about well-being is the question of what things are in themselves of ultimate benefit or harm to a person, or directly make them better or worse off.

The purpose of this article is to explore a fundamental ethical approach to nursing and to suggest some proposals, based on this approach, for nursing ethics education. The major point is that the kind of nursing ethics education that is given reflects the theory that is held of nursing. Three components of a fundamental ethical view on nursing are analysed more deeply: (1) nursing considered as moral practice; (2) the intersubjective character of nursing; and (3) moral perception. It is argued (...) that the fundamental ethical view on nursing goes together with a virtue ethics approach. Suggestions are made for the ethics education of nurses. In particular, three implications are considered: (1) an attitude versus action-orientated ethics education; (2) an integral versus rationalistic ethics education; and (3) a contextual model of ethics education. It will also be shown that the European philosophical background offers some original ideas for this endeavour. (shrink)

"Feminism, Theory and the Politics of Difference" looks at the question of difference across the full spectrum of feminist theory from liberal, radical, lesbian ...

The impact of neoliberal reforms of education systems on the work of teachers and school leaders, particularly in relation to high-stakes accountability frameworks, has been extensively studied in recent decades. One significant aspect of neoliberal schooling is the emergence of quasi-autonomous public schools (such as Academies in England, Charter Schools in the USA and Independent Public Schools in Australia), characterised by heterarchical governance models, the promotion of entrepreneurial leadership cultures, and the promotion of a discourse of pursuing educational equity by (...) means of ‘achievement for all’. This paper explores the emergence of a mode of teacher professionalism characteristic of these quasi-autonomous schools, and conceptualises this as being ‘neo-performative’. The neo-performative profession is shaped by the shift in the focus of the regulation and management of schools from ‘governing to governance’, and the consequential rise of the ‘responsibilised profession’, and marked by the emergence of an entrepreneurial model of school leadership. The paper argues that this new conceptualisation of teacher professionalism requires further, more focused, empirical study in order to explore how neoperformative teachers and school leaders articulate their vision of educational equity and social justice, and how they enact this vision in an increasingly intensified high-stakes accountability culture. (shrink)

A typical theorem of conaexive logics is Aristotle''s Thesis(A), (AA).A cannot be added to classical logic without producing a trivial (Post-inconsistent) logic, so connexive logics typically give up one or more of the classical properties of conjunction, e.g.(A & B)A, and are thereby able to achieve not only nontriviality, but also (negation) consistency. To date, semantical modellings forA have been unintuitive. One task of this paper is to give a more intuitive modelling forA in consistent logics. In addition, while inconsistent (...) but nontrivial theories, and inconsistent nontrivial logics employing prepositional constants (for which the rule of uniform substitution US fails), have both been studied extensively within the paraconsistent programme, inconsistent nontrivial logics (closed under US) do not seem to have been. This paper gives sufficient conditions for a logic containingA to be inconsistent, and then shows that there is a class of inconsistent nontrivial logics all containingA. A second semantical modelling forA in such logics is given. Finally, some informal remarks about the kind of modellingA seems to require are made. (shrink)

We consider the influence that John Forrester’s work has had on thinking in, with, and from cases in multiple disciplines. Forrester’s essay ‘If p, Then What? Thinking in Cases’ was published in History of the Human Sciences in 1996 and transformed understandings of what a case was, and how case-based thinking worked in numerous human sciences (including, centrally, psychoanalysis). Forrester’s collection of essays Thinking in Cases was published posthumously, after his untimely death in 2015, and is the inspiration for the (...) special issue we introduce. This comprises new research from authors working in and across the history of science and medicine, gender and sexuality studies, philosophy of science, semiotics, film studies, literary studies and comparative literature, psychoanalytic studies, medical humanities, and sociology. This research addresses what it means to reason in cases in particular temporal, spatial, or genre-focused contexts; introduces new figures (e.g. Eugène Azam, C. S. Peirce, Michael Balint) into lineages of case-based reasoning; emphasizes the unfinished and unfinishable character of some case reading and autobiographical accounts; and shows the frequency with which certain kinds of reasoning attempted with cases fail (often in instructive ways). The special issue opens up new directions for thinking and working with cases and case-based reasoning in the humanities and human sciences. (shrink)

In previous work, I defend the following disparity between moral and epistemic facts: whereas moral facts are irreducibly normative, epistemic facts – facts such as that some subject is epistemically justified in believing something – are reducible to facts from some other domain (such as facts about probabilities). This moral-epistemic disparity is significant because it undercuts an important kind of argument for robust moral realism. My defense of epistemic reductionism and of the moral-epistemic disparity has been criticized by Richard Rowland (...) (2013) and by Terence Cuneo and Christos Kyriacou (forthcoming). This paper aims to rebut these criticisms and, more generally, to clarify and strengthen the case for epistemic reductionism and the moral-epistemic disparity. (shrink)

Chris Horner and Emrys Westacott present a clear and accessible introduction to some of the central problems of philosophy through challenging and stimulating the reader to think beyond the conventional answers to fundamental questions. No previous knowledge is assumed, and in lively and provocative chapters the authors invite the reader to explore questions about the nature of science, religion, ethics, politics, art, the mind, the self, knowledge and truth. Each chapter includes inset boxes providing links to classic philosophy texts (...) on the issues discussed. In addition, the book relates the adventure of philosophy to some of the key principles of critical thinking. (shrink)

We investigate expansions of the ordered field of real numbers equipped with a family of real power functions. We show in particular that the theory of the ordered field of real numbers augmented by all restricted analytic functions and all real power functions admits elimination of quantifiers and has a universal axiomatization. We derive that every function of one variable definable in this structure, not ultimately identically 0, is asymptotic at + ∞ to a real function of the form x (...) cxr, c ≠ 0; in particular, this structure is polynomially bounded. Furthermore, given any definable function f:U → with U open in n, if α ε U and f is infinitely differentiable at α, then f is real analytic in a neighborhood of α. (shrink)

More often than not, notes are conceptualized as a technology for helping students stay focused on and attentive to subject matter deemed educationally valuable. This article concerns itself, however, with how notes may interrupt and render inoperative this learning function. To probe the question of attention and distraction, the authors devised an experiment in note taking. Our question is whether or not these forms of rendering the learning function of notes inoperative have any educational value. In conclusion, we suggest that (...) such activities, while divorced from official, outcomes-based learning, do indeed have educational meaning: they make present the potentiality for thinking and acting without forcing such potentiality into measurable forms. What remains is the notes themselves, and the notational effects they in turn generated and continue to generate. (shrink)

This article returns to the debate about the relative importance of the productive forces and the relations of production in the feudal mode of production. It argues, using western medieval evidence, that this relation is an empirical one and varies between modes, maybe also inside modes; and that, in the specific case of feudalism, not only were the relations of production the driving force, but developments in the productive forces actually depended upon them.

The question of the interpretation of impossible pictures is taken up. Penrose's account is reviewed. It is argued that whereas this account makes substantial inroads into the problem, there needs to be a further ingredient. An inconsistent account using heap models is proposed.

An argument that science is indeed 'socially constructed' but in a way that exposes it to a Darwinian version of variability and selection which ensures its success.

Support vector machines (SVMs) are being used increasingly in affective science as a data-driven classification method and feature reduction technique. Whereas traditional statistical methods typically compare group averages on selected variables, SVMs use a predictive algorithm to learn multivariate patterns that optimally discriminate between groups. In this review, we provide a framework for understanding the methods of SVM-based analyses and summarize the findings of seminal studies that use SVMs for classification or data reduction in the behavioral and neural study of (...) emotion and affective disorders. We conclude by discussing promising directions and potential applications of SVMs in future research in affective science. (shrink)

Farmers are key actors in the transition towards sustainable agricultural practices. Therefore, it is important to understand farmers’ motivations to encourage lasting change. This study investigated how farmers from the two different social contexts of the northeast US and Denmark perceive sustainability. Twenty farmers constructed Fuzzy Cognitive Maps to model their practices and perceived outcomes. The maps were analyzed using social capital as an analytical framework. The results showed that sustainability perceptions differed between US and Danish farmers. Specifically, Danish farmers (...) focused mainly on environmental sustainability while US farmers distributed their focus more evenly across environmental, social, and economic factors. Further, US and Danish farmers had different notions of community engagement. US farmers emphasized the importance of interdependence with their non-farmer community members, where farmers contributed to the wellbeing and livelihoods of non-farmers and vice versa. For Danish farmers, the importance of community engagement lay mainly in localizing food systems, the public image of farming, and the cultural value of farms. Differences in the dominant types of social capital (farmer-to-government vs. farmer-to-non-farmer-community) can explain this pattern. We argue that understanding social capital and primary level of influence can lead to more effective and efficient policies. (shrink)

As one approach to examining the way ethical decisions are made, we asked experts and novices to review a set of scenarios that depict some important ethical tensions in research. The method employed was “protocol analysis,” a talk-aloud technique pioneered by cognitive scientists for the analysis of expert performance. The participants were asked to verbalize their normally unexpressed thought processes as they responded to the scenarios, and to make recommendations for courses of action. We found that experts spent more time (...) working through the decision-making process than novices and also raised substantially more concerns than novices. Differences also exist among the three groups of experts. (shrink)

‘Organisational failure’ is central to medical ethics. In the National Health Service (NHS), we usually examine failures at hospital level. We have had around 100 hospital inquiries since the first in 1969, into Ely Hospital, Cardiff. This year, we had the Ockenden Report into Shrewsbury and Telford Hospital. Last year, we had the Outram Inquiry into West Suffolk Hospital. In 2020, the James Inquiry into Ian Paterson. And, before that, Morecombe Bay, Gosport War Memorial, Mid Staffordshire, Liverpool Community Health, Winterbourne (...) View, Anthony Ledward, Stoke Mandeville, Bristol Royal Infirmary and so on. As Taylor says, these reports teach us clinical failure usually has an institutional setting and that blaming individuals overlooks working ‘culture’. They have also led to: (a) new regulatory bodies to manage, investigate and improve NHS standards, (b) new codes of conduct to mandate reporting of serious accidents—backed up by the Whistle-blower’s Act and explicit statutory duties of disclosure, (c) root cause analysis to encourage consistent investigations so we can learn from reliable data and (d) new ‘Speaking Up Guardians’ and a Patient Safety Commissioner to encourage informal discussion about patient safety. What is so surprising is how little these inquiries and reforms have achieved on the larger scale. Of course, we must …. (shrink)

The modern biomedical research laboratory is increasingly defined by dynamic social material conditions requiring researchers to traverse multiple shifting cognitive ecologies within day-to-day practice. Although the complexity of biomedical research is well known, the mechanisms by which the social and material organisation of this space is negotiated has yet to be fully considered. Integrating insights from Material Engagement Theory and Enactive Cognition with observations undertaken within a biomedical research laboratory, this paper develops an understanding of how actors are able to (...) respond to the dynamically changing world that is enacted with and around them. (shrink)

In this article we address the question of how many impossible images Escher produced. To answer requires us first to clarify a range of concepts, including content, ambiguity, illusion, and impossibility. We then consider, and reject, several candidates for impossibility before settling on an answer.

We explore the science of mass extinction, link it to industrial civilization, use the concept of the banality of evil to explain the ethical situation, and then explain the various ways in which mass extinction poses further ethical problems within that situation, especially of environmental justice and the loss of value. Overall, humankind risks a profound failure of autonomy, perhaps our greatest achievement. For those who want to take action, we recommend the project of anthroponomy and large-unit/deep-branching conservation.

As an intellectual, economic, political and legal project, neoliberalism is not directed towards the rolling back of the state as an aim in itself. While its deregulatory tendencies, its commodification of public services and the undermining of systems of social welfare superficially suggest a generalised reduction in state power, it has been clear from the early 1980s that one of neoliberalism’s primary concerns has been the authoritarian reshaping of state power to engineer particular social outcomes, whether in criminal justice, the (...) disciplining of organised labour, the militarisation of national territory and migration, or the extension and deepening of regimes of austerity. This article introduces the recent work of Maurizio Lazzarato, who has argued that the asymmetrical creditor-debtor relationship is now the archetype of contemporary, neoliberal social relations. Ultimately, Lazzarato’s perspective tends to exaggerate the totalising powers of finance capital and leads him to endorse a form of political voluntarism, which fails to address the role of the neoliberal state as a site for forms of authoritarianism which are not solely generated by the debt relation. As a response, it will be suggested that aspects of Nicos Poulantzas’s concept of ‘authoritarian statism’ can be used to both strengthen our understanding of the authoritarian characteristics of the neoliberal state, and to imagine possibilities for resisting its expressions of power. (shrink)

Agalev and Ecolo consented to supporting the institutional reform of Belgium. Product-policy will be assigned to the federal government. Ecotaxes, fiscal instruments that fit in a product policy, are introduced. Three criteria are defined: 1) the primary goal is to bring about a change of behaviour, 2) the revenues are allocated towards environmental policy and 3) alternative products should be available. Whoever wants to know society, must try to change it. The enormous resistance of industry cannot only be explained by (...) economic considerations. Much more, it is a matter of pure power : who has something to say about what. But resistance and desinformaton also came from consumers' organisations, thewritten press in its comments and even from some 'environmental scientists'.Authors wonder what farces will be unleashed when the discussion on 'reducing consumption ' starts. (shrink)

Fundamental movement skill proficiency does not develop solely due to maturation, but also via diverse perceptual-motor experiences across childhood. Practicing gymnastics has been shown to improve postural control. The purpose of the present study was to examine potential changes to postural control of children following a course of educational gymnastics. Two groups of children both completed 20 × 45-min physical education lessons; one group completed educational gymnastics lessons in school delivered by a professional coach, the other group completed their typical (...) PE classes. Unipedal balancing performance was assessed by calculating the percentage of successful trials made. Postural sway dynamics were explored by calculating center-of-pressure sample entropy, 95% ellipse sway area and sway velocity. Measurements were taken before the lessons began and immediately after the lessons were completed. The gymnastics group performed better than the typical PE group at unipedal balancing. Females outperformed males in both groups. Males made different changes to postural control compared to females across 3 months. Educational gymnastics enabled children in a critical period of development to make more rapid improvements to postural performance and control. Novel movement experiences, like those offered by educational gymnastics, may have a positive influence on postural control and importantly, physical literacy. Future work should examine how sex effects the development of postural control strategies in young children. (shrink)

This handbook is the first to explore the growing field of experimental semantics and pragmatics. Following an introduction from the editors, the chapters in this volume offer an up-to-date account of research in the field spanning 31 different topics, as well as identifying questions and methods for future research.

As the global prevalence of Alzheimer’s disease increases, the need to understand family caregiving becomes increasingly pressing. I argue that there is an under-recognized form of caregiving for people with early to mid-stage Alzheimer’s disease. This type of caregiving involves, roughly, helping people reason through their values. It arises along with the loss of the capacity for executive functioning. Moreover, it is prone to give rise to moral distress, which is an under-recognized vulnerability in family caregiving. Categories of family caregiving (...) thus need to be expanded, and moral distress needs to be recognized not only in the context of nursing. (shrink)

In current debates concerning atheism, two positions are considered possible: naturalistic atheism or anti-naturalistic theism. Anti-naturalistic theism is motivated by the failure of naturalism to explain the fundamental nature of reality. We, however, endorse anti-naturalistic atheism by reviving the ‘anthropomorphic critique’, arguing that theism misattributes human traits to the deity. Anti-naturalistic atheism is better suited to refute theists, since it undercuts their appeal to science's inadequacies. We trace the anthropomorphic critique from Hume's Dialogues, through Kant's epistemology, and conclude with its (...) reception in Feuerbach. The anthropomorphic critique is an epistemological – not metaphysical – thesis, hence, it is agnostic about the fundamental nature of reality. Yet it convincingly shows that theism is not a tenable position. In essence, we aim to decouple atheism from naturalism, on the basis of a salient critique in the history of modern philosophy, in order to ameliorate current debates between atheists and theists.Export citation. (shrink)

We are, at present, at a crisis point where the rhetoric and policy practices surrounding the preservation of the American state, as espoused by its highest-ranking officials, has ceased to mask the racism and xenophobia that have long characterized it. Faced with a state politics that is more than ever desirous of visiting its fears upon the most vulnerable, an intervention in the political via critical practice—practice capable of lending nuance to the conception of the political and exposing its vulnerabilities—is (...) urgently necessary. To do so requires an approach capable of engaging in a rigorous way with the state’s conception of itself and the machinery it employs to pursue that conception, a machinery that... (shrink)

A second-person approach that prioritizes dyadic emotional interaction is not well equipped to explain the origins of the understanding of mind conceived as intentionality. Instead, the critical elements that will deliver the understanding of self and other as persons with intentionality are shared object-centered interactions that include not only emotional engagement, but also joint attention and joint goal-directed action.

Although my position is in basic agreement with the notion that war and militarism are feminist issues, I argue that approaches to the ethics of war and peace which do not consider "peacetime" military violence are inadequate for feminist and environmentalist concerns. Because much of the military violence done to women and ecosystems happens outside the boundaries of declared wars, feminist and environmental philosophers ought to emphasize the significance of everyday military violence.

A principle of continuity due to Leibniz has recently been revived by Graham Priest in arguing for an inconsistent account of motion. This paper argues that the Leibniz Continuity Condition has a reasonable interpretation in a different, though still inconsistent, class of dynamical systems. The account is then applied to the quantum mechanical description of the hydrogen atom.

This paper aims to distinguish and classify sixteen versions of the Necker cube. In particular, it is shown how to describe inconsistent and incomplete theories which correspond in a systematic way to these sixteen diagrams. Concerning two of these sixteen cubes, there is a natural intuition that there is a sense in which they inconsistent. It is seen that this intuition is vindicated by an analysis in which their corresponding theories turn out to be globally inconsistent but not locally inconsistent, (...) while various other cubes of the sixteen are merely locally inconsistent. The Routley functor is seen to be useful in classifying the relations between these diagrams. (shrink)

In this article we argue that commercial boycotting is not an uncontested economic right. Rather, the practice of boycotting often requires further moral justification. We argue that this justification should not rely solely on the consequences of boycotting, nor should it rely solely on the complicity of the consumer. We suggest that both justifications are subject to pressing objections. In light of these objections, we outline an alternative non‐consequentialist justification of commercial boycotting that is grounded in the moral values of (...) conscience and personal integrity. We then explore the scope of this justification in the legal realm. We focus on cases where consumers lack freedom of exchange due to their contractual obligations and conclude by defending a qualified legal right to breach contracts on conscientious grounds. (shrink)

This paper explores the way some contemporary feminist Pagan practitioners talk about nature and goddess. I see these feminist Pagans as providing an example of a religion of nature, much like that of Donald Crosby’s that focuses on nature as the ultimate. However, unlike Crosby’s religion of nature, which could be perceived as isolationist, these feminist Witches’ willingness to maintain theistic language through religious fictionalism, even though non-realist, supports their community participation in an increasingly realist Pagan context.

Human right-handedness does not originate in vocalisation as such but in selection pressures for structuring complex sequences of digital signals internally, as if in a vacuum. Cautious receivers cannot automatically accept signals in this way. Biological displays are subjected to contextual scrutiny on a signal-by-signal basis – a task requiring coordination of both hemispheres. In order to explain left cerebral dominance in human manual and vocal signalling, we must therefore ask why it became adaptive for receivers to abandon caution, processing (...) zero-cost signals rapidly and on trust. (shrink)