BackgroundGenetics and genomics research (GGR) is increasingly being conducted around the world; yet, researchers and research oversight entities in many countries have struggled with ethical challenges. A range of ethics and regulatory issues need to be addressed through comprehensive policy frameworks that integrate with local environments. While important efforts have been made to enhance understanding and awareness of ethical dimensions of GGR in Africa, including through the H3Africa initiative, there remains a need for in-depth policy review, at a country-level, to (...) inform and stimulate local policy development and revision on the continent.MethodsTo identify and characterize existing ethics-related guidelines and laws applicable to GGR across much of Africa, we conducted a scoping review of English language policy documents identified through databases, repositories, and web searches. Thirty-six documents were included and coded using a framework that contained a range of themes across five analytical categories: (1) respect, (2) beneficence, (3) justice, (4) independent oversight, and (5) bans and prohibitions. Data analysis software (NVivo 12) was used to organize, code, and tabulate information according to document characteristics and topics. Illustrative examples of policy requirements were selected for inclusion.ResultsDocuments that met inclusion criteria spanned 20 years; published between 1996 and 2018, with the majority (58%) published after 2009. About two-thirds were denoted as “guidelines,” and slightly more than half were non-exclusive to GGR. Very few (six) country-level documents identified were specific to GGR. Requirements related to the principle of “respect” appeared most often across all documents, relative to other principles and processes. The most commonly stated ban was on reproductive cloning. Other prohibitions applied to germline editing, undue inducements in research, sample use for commercial purposes, employee mandatory DNA testing, fetal sex selection, stem cell use, eugenics, and research without public health benefits.ConclusionsEnforceable policies that are indispensable to the ethical conduct and review of GGR are either deficient or missing in many African countries. Existing international, GGR-specific ethics guidelines can be used to inform GGR policy development at a country-level, in conjunction with insight from country specific ethics committees and other local stakeholders. (shrink)

In this issue, Ellen Fox and colleagues report on their national study on ethics consultation in U.S. hospitals, following up on the previous 1999–2000 landmark study. Th...

While it is widely assumed that greater diversity in corporate governance will enhance a firm’s corporate social performance, this study considers an alternative thesis which relates managerial control to corporate philanthropy. The study empirically evaluates both board diversity and managerial control of the board as possible predictors of corporate philanthropy. The demonstration of a positive relationship between managerial control and corporate philanthropy contributes to our understanding that corporate social performance results from a complex set of economic and social motives. Possible (...) future research and managerial implications are discussed. (shrink)

This is a book about speech and the silencing of speech; about who gets to speak and who does not; about who is listened to and who is ignored. In this down-to-earth analysis of the democratic principle of freedom of speech, Betty McLellan insists that, if this prized democratic principle is to have any continuing credibility, free speech must be free for all.

Visual narratives like comics involve a range of complex cognitive operations in order to be understood. The Parallel Interfacing Narrative‐Semantics (PINS) Model integrates an emerging literature showing that comprehension of wordless image sequences balances two representational levels of semantic and narrative structure. The neurocognitive mechanisms that guide these processes are argued to overlap with other domains, such as language and music.

`Hans Cohn has given us a personal and valuable statement about the theoretical underpinnings of his work as a psychotherapist. These can be little doubt about his contribution to our thinking practice is invaluable. Students will find Cohn's easygoing exposition of complex ideas enormously helpful' - Professor Emmy van Deurzen, Existential Analysis `One of the most important books published this year. This long-awaited book by the foremost expert on the relationship between Heidegger and psychotherapy, manages to encapsulate the (...) essence of Heidegger's thinking and make of understandable and relevant to therapists without losing any of the original meaning' - Counsellingbooks.com Anyone interested in modern philosophy is familiar with the name of Martin Heidegger but there is a serious gap in even the most complete accounts of his life and thought. This is Heidegger's association with, and influence on, psychotherapy. Hans C Cohn explores the role of Heidegger's thought in providing an alternative basis for psychotherapeutic practice to the dominant psychodynamic, humanistic and cognitive approaches, also focusing strongly on the practical therapeutic relevance of Heidegger's ideas. This book will be essential reading for students and teachers of modern philosophy, as well as existential psychotherapists, and all practitioners interested in existential approaches to therapy. (shrink)

Race or ethnic identity, despite its imprecise categorization, is a useful means of identifying population differences in mechanisms of disease and treatment effects. Therefore, race and other arbitrary demographic and physiological variables have appropriately served as a helpful guide to clinical management and to clinical trial participation. The African-American Heart Failure Trial was carried out in African-Americans with heart failure because prior data had demonstrated a uniquely favorable effect in this subpopulation of the drug combination in BiDil. The remarkable effect (...) of the drug in reducing mortality in this study has illuminated an important new mechanism of therapy for heart failure. Application of these findings need not be confined to the population studied, but the observation highlights the need for more precise ways to identify individual responsiveness to therapy. (shrink)

An argument that the major metaphysical theories of facts give us no good reason to accept facts in our catalog of the world. -/- In this book Arianna Betti argues that we have no good reason to accept facts in our catalog of the world, at least as they are described by the two major metaphysical theories of facts. She claims that neither of these theories is tenable—neither the theory according to which facts are special structured building blocks of reality (...) nor the theory according to which facts are whatever is named by certain expressions of the form “the fact that such and such.” There is reality, and there are entities in reality that we are able to name, but, Betti contends, among these entities there are no facts. -/- Drawing on metaphysics, the philosophy of language, and linguistics, Betti examines the main arguments in favor of and against facts of the two major sorts, which she distinguishes as compositional and propositional, giving special attention to methodological presuppositions. She criticizes compositional facts (facts as special structured building blocks of reality) and the central argument for them, Armstrong's truthmaker argument. She then criticizes propositional facts (facts as whatever is named in “the fact that” statements) and what she calls the argument from nominal reference, which draws on Quine's criterion of ontological commitment. Betti argues that metaphysicians should stop worrying about facts, and philosophers in general should stop arguing for or against entities on the basis of how we use language. (shrink)

The paper outlines a model-theoretic framework for investigating and comparing a variety of mereotopological theories. In the first part we consider different ways of characterizing a mereotopology with respect to (i) the intended interpretation of the connection primitive, and (ii) the composition of the admissible domains of quantification (e.g., whether or not they include boundary elements). The second part extends this study by considering two further dimensions along which different patterns of topological connection can be classified - the strength of (...) the connection and its multiplicity. (shrink)

INDIAN AND WESTERN PHILOSOPHY- A Study in Contrasts By BETTY HEIMANN. Originally published in I937. Contents include: 1. INTRODUCTION 13 2. THEOLOGY 2Q 3. ONTOLOGY AND ESCHATOLOGY 46 4. ETHICS 63 5. LOGIC 79 6. AESTHETICS 98 7. HISTORY AND APPLIED SCIENCE Il6 8. THE APPARENT RAPPROCHEMENT BETWEEN WEST AND EAST 131 EPILOGUE 147 INDEX OF PROBLEMS TREATED 149. INDIAN AND WESTERN PHILOSOPHY. CHAPTER I. INTRODUCTION: ONE ceuvre dart est un coin de la creation vu d travers un temperament, (...) says Zola and we may be justified in applying this aphorism when we venture on a some what similar survey and attempt an artificial selection from World-Philosophy throughout the ages. My aim, however, is not to elaborate any finished outline of all the philosophical conceptions that have arisen in East and West up to the present day, but merely to indicate the essential and fundamental tendencies and principles. In tracing the sources of Western Philosophy to Plato and Aristotle, and still earlier to the pre-Socratics of ancient Greece, I became convinced that all translations are, to a greater or less degree, modes of interpretation. I studied the Classics, therefore, from the linguistic standpoint, and this procedure ultimately developed into a philosophical method intimately associated with the psychological aspects of Philology. In pursuing this task I discovered at the same time the specifically material basis of all Western thought. In other words in my regress from the history of modern Philosophy to the dawn of Greek speculation, or to repeat to the pre-Socratics, I found myself able to trace the main trends of Western Philosophy to the prior era of the Greek Sophists, whose outstanding role as the actual founders of Western thought is, in my opinion, too frequently underestimated. Their basic dogma which has held good in the West ever since was, Man is the Measure of all things. At this point an equally important feature must be emphasized for throughout this age of the Sophists there persists the profound contrast between the typically Western, and the equally distinctive Eastern, intellectual and spiritual atmospheres. In this connection, still further, I was deeply impressed by the far-reaching divergence of the Western anthropological tendency from the older cosmic out look upon Man as being part and parcel of the Universe And this radical antithesis is to be dis cerned in contemporary Greek drama. For Aeschylus, the Marathonomaches, creates all his immortal tragedies in the genuinely cosmic mood. Every in fraction of cosmic order, with no single exception, must generate its own inevitable reaction, and also its punishment, in order that the primal cosmic harmony may once more be restored... (shrink)

This paper describes the topological aspect of a logic-based, artificial intelligence approach to formalising the qualitative description of spatial properties and relations, and reasoning about those properties and relations. This approach, known as RCC theory, has been under development for several years at the University of Leeds. The main rationale for this project is that qualitative descriptions of spatial properties and relationships, and qualitative spatial reasoning, are of fundamental importance in human thinking about the world: even where quantitative spatial data (...) are most important, they must be attached to the components of a perceived spatial structure if we are to make use of them. RCC theory covers other qualitative aspects of spatial description and reasoning, but the topological properties and relations of spatially extended entities are fundamental to our work. The topological formalisms used by mathematicians are, in general, not well suited to the task of formalising the kinds of ‘common-sense’ or ‘everyday’ qualitative spatial description and reasoning which are our primary interest. Nevertheless, we must come to grips with the concepts of topology as practised by mathematicians if we are not to risk constantly ‘reinventing wheels’. (shrink)

Betty Powell; XII*—Descartes' Machines, Proceedings of the Aristotelian Society, Volume 71, Issue 1, 1 June 1971, Pages 209–222, https://doi.org/10.1093/aristot.

How can we best reconstruct the origin of a notion, its development, and possible spread to multiple fields? We present a pilot study on the spread of the notion of conceptual scheme. Though the notion is philosophically important, its origin, development, and spread are unclear. Several purely qualitative and competing historical hypotheses have been offered, which rely on disconnected disciplinary traditions, and have never been tested all at once in a single comprehensive investigation fitting the scope of its subject matter. (...) As a step toward such an investigation, we trace the use of the bigram “conceptual scheme” in about 42,000 US journal articles in social sciences from 1888-1959 by using a novel method combining a quantitative procedure aided by basic computational techniques with qualitative elements informed by Betti and van den Berg (2014)’s ‘model approach to the history of ideas’. (shrink)

The History of Ideas is presently enjoying a certain renaissance after a long period of disrepute. Increasing quantities of digitally available historical texts and the availability of computational tools for the exploration of such masses of sources, it is suggested, can be of invaluable help to historians of ideas. The question is: how exactly? In this paper, we argue that a computational history of ideas is possible if the following two conditions are satisfied: (i) Sound Method . A computational history (...) of ideas must be built upon a sound theoretical foundation for its methodology, and the only such foundation is given by the use of models , i.e., fully explicit and revisable interpretive frameworks or networks of concepts developed by the historians of ideas themselves. (ii) Data Organisation. Interpretive models in our sense must be seen as topic-specific knowledge organisation systems (KOS) implementable (i.e. formalisable) as e.g. computer science ontologies. We thus require historians of ideas to provide explicitly structured semantic framing of domain knowledge before investigating texts computationally, and to constantly re-input findings from the interpretive point of view. In this way, a computational history of ideas maximally profits from computer methods while also keeping humanities experts in the loop. We elucidate our proposal with reference to a model of the notion of axiomatic science in 18th -19th century Europe. (shrink)

Dans cet entretien, Daniel Cohn-Bendit déplore l’atonie de la gauche française qui n’a pas voulu, lors de ces élections, réunir ses composantes sociale, écologiste et réformiste derrière Raphaël Glucksman autour d’un projet européen prônant la fédéralisation de l’UE. Or, cette unité est indispensable pour penser les États-Unis d’Europe face à trois insécurités majeures : la Covid, la guerre en Ukraine et le délabrement de la planète. Il s’agit de traiter ces trois insécurités ne même temps sans sacrifier l’objectif écologique. (...) Par quels moyens? Ce pourrait être par un grand emprunt européen garanti par la puissance du marché de ses 460 millions d’habitants ou par la création de partis transnationaux européens. Le navire Europe a encore du chemin à parcourir. Il flotte mais ne coule pas. (shrink)

In rhetoric, an orator needs both a large vocabulary and a stock of commonplaces and arguments. Erasmus put them together in his De duplici copia verborum ac rerum . In this sixth volume of the first Ordo of the Amsterdam edition of the Latin texts of Erasmus, Betty Knott has edited the Latin text and added an English introduction and commentary, providing philological and historical information which helps the reader to understand the text and identify its sources.

Le monde occidental s'interroge aujourd'hui sur la passion de la mort qui pousse de jeunes terroristes au suicide et au crime. Le présent essai traite d'une autre fascination, non moins troublante : celle qui travaille sourdement les grands textes de notre modernité. Après Alexandre Kojève, l'écriture de Georges Bataille, de Maurice Blanchot, de Jacques Derrida ou de Jacques Lacan, laisse transparaître un lyrisme de la destruction, un engouement pour l'abîme, qu'il faut savoir reconnaître sous la rigueur de la pensée. D'où (...) vient cette esthétique du malheur? Quels enjeux recouvre-t-elle? Au fil d'une minutieuse lecture, l'auteur s'attache à dénuder un complexe de valeurs et d'affects qui remontent aux origines symboliques de notre civilisation. On entrevoit peu à peu que cette revendication de la mort pourrait bien n'être que le signe inversé de la grande protestation humaine, de sa soif d'infini et de son désir d'être. Betty Rojtman, née à Paris, a dirigé le département de littérature française à l'université hébraïque de Jérusalem. Elle situe sa recherche au carrefour de la pensée contemporaine et de l'exégèse juive traditionnelle. Parmi ses publications : Feu noir sur feu blanc. Essai sur l'herméneutique juive (1986); Une grave distraction (préface de Paul Ricoeur, 1991) ; Une rencontre improbable (2002) et Moïse, prophète des nostalgies (2007). (shrink)

This book's importance is derived from three sources: careful conceptualization of teacher induction from historical, methodological, and international perspectives; systematic reviews of research literature relevant to various aspects of teacher induction including its social, cultural, and political contexts, program components and forms, and the range of its effects; substantial empirical studies on the important issues of teacher induction with different kinds of methodologies that exemplify future directions and approaches to the research in teacher induction.

A Bilingual International Conference on the History and Actuality of the Polish Contribution, from the Lvov-Warsaw school to phenomenology, to Twentieth Century Philosophy. Colloque international bilingue portant sur l'histoire et l'actualité de la contribution polonaise, de l'école de Lvov-Varsovie à la phénoménologie, à la philosophie du vingtième siècle.

As a psychologist working with individuals, couples, and groups over the past 25 years, I have become convinced that group therapy holds effective possibilities for treatment that neither individual nor couples therapy can match. In theorizing about why group work holds such potency for changing lives, I have come to place it in a Sartrean context. I believe that group therapy offers a greater possibility for revolutionary praxis than individual or couples therapy. In saying this, I am not talking about (...) political or social revolution, but rather the possibility for radical change in a person's orientation toward the world, which groups tend to provoke and reinforce in a way that is more difficult in other forms of therapy. Sartre's concept of groups in his later philosophy, especially in Search for a Method and the Critique of Dialectical Reason, can help us to understand better this transformative power of groups. Such power is not always positive, of course, as Sartre himself recognizes—and as social and political history so amply demonstrates. But the nature of therapy groups is such that they at least have the potential for positive results. (shrink)