Can art, religion, or philosophy afford ineffable insights? If so, what are they? The idea of ineffability has puzzled philosophers from Laozi to Wittgenstein. In Ineffability and its Metaphysics: The Unspeakable in Art, Religion and Philosophy, Silvia Jonas examines different ways of thinking about what ineffable insights might involve metaphysically, and shows which of these are in fact incoherent. Jonas discusses the concepts of ineffable properties and objects, ineffable propositions, ineffable content, and ineffable knowledge, examining the metaphysical (...) pitfalls involved in these concepts. Ultimately, she defends the idea that ineffable insights as found in aesthetic, religious, and philosophical contexts are best understood in terms of self-acquaintance, a particular kind of non-propositional knowledge. Ineffability as a philosophical topic is as old as the history of philosophy itself, but contributions to the exploration of ineffability have been sparse. The theory developed by Jonas makes the concept tangible and usable in many different philosophical contexts. (shrink)

We have lost one of the giants of the twentieth century physics when Yoichiro Nambu passed away in July, 2015, at the age of 94. Today's Standard Model, though still incomplete in many respects, is the culmination of the most successful theory of the Universe to date, and it is built upon foundations provided by discoveries made by Nambu in the 1960s: the mechanism of spontaneously broken symmetry in Nature (with G Jona-Lasinio) and the hidden new SU(3) symmetry of quarks (...) and gluons (with M-Y Han). In this volume honoring Nambu's memory, World Scientific Publishing presents a unique collection of papers written by his former colleagues, collaborating researchers and former students and associates, not only citing Nambu's great contributions in physics but also many personal and private reminiscences, some never told before. This book is a volume for all who benefited not only from Nambu's contributions toward understanding the Universe but also his warm and kind persona. It is a great addition to the history of contemporary physics. (shrink)

Nous allons analyser le passage de la conception freudienne de l'inconscient à celle de Lacan, mise en place à partir de son dernier enseignement. Dans celle-ci, l'interprétation n'est plus la seule clé de lecture de l'inconscient. Nous allons montrer l'articulation des deux inconscients avec la notion de «temps», et en quoi, ces deux différentes conceptions déterminent la direction de la cure. Dans la première, l'inconscient est plutôt envisagé à partir du temps passé, alors que dans la deuxième à partir du (...) futur: la contingence devient ainsi l'élément fondamental pour penser l'inconscient. La psychanalyse se montre alors comme une discipline qui ne vise pas seulement à déceler les mécanismes déterminés de l'inconscient, mais aussi comme pratique capable d'accueillir l'inattendu et de l'exploiter dans la cure. Vamos a analizar el pasaje de la concepción freudiana del inconsciente a la de Lacan, concebida a partir de su última enseñanza. En esta, la interpretación no es más la sola clave de lectura del inconsciente. Mostraremos la articulación de ambos inconscientes con la noción de "tiempo", y cómo estas dos diferentes concepciones determinan la dirección de la cura. En la primera, el inconsciente es sobre todo contemplado a partir del tiempo pasado, mientras que en la segunda a partir del futuro: la contingencia se hace así el elemento fundamental para pensar en el inconsciente. El psicoanálisis se muestra entonces como una disciplina que no pretende solamente descubrir los mecanismos determinados del inconsciente, sino también como práctica capaz de acoger lo inesperado y explotarlo en la cura. (shrink)

Dal 1992, anno della Conferenza di Rio per la Terra, ad oggi è trascorso un lasso di tempo sufficiente per valutare se e come il principio di responsabilità, nella versione elaborata da Hans Jonas, sia stato attuato a livello normativo in relazione alle questioni ambientali connesse al cambiamento climatico, sia in ambito internazionale che europeo. In particolare, lo studio dell’evoluzione politico-giuridica dello sviluppo sostenibile rappresenta un interessante osservatorio da cui valutare la capacità dell’umanità di non mettere in pericolo le (...) condizioni della sopravvivenza indefinita dell’umanità sulla terra. A muovere da queste considerazioni, l’articolo si propone di analizzare, lungo due direttrici, l’attuazione etico-giuridica del principio di responsabilità formulato da Jonas. La prima direttrice avrà a oggetto alcuni dei principi che hanno costruito la struttura etico-giuridica dello sviluppo sostenibile a livello internazionale ed europeo. La seconda direttrice si concentrerà sulla proposta per una EU Fundamental Charter for the Rights of Nature. L’intento critico e, per certi versi, provocatorio dell’articolo è di riaccendere l’attenzione sugli elementi emergenti dagli spunti riflessivi di Jonas e dalla visione originaria dello sviluppo sostenibile, che possono essere utili a determinare il cambiamento di rotta auspicato decenni fa, ma non ancora portato a compimento. (shrink)

Objectives: To study the attitudes of both medical and non-medical students towards the do-not-resuscitate decision in a university in Hong Kong, and the factors affecting their attitudes.Methods: A questionnaire-based survey conducted in the campus of a university in Hong Kong. Preferences and priorities of participants on cardiopulmonary resuscitation in various situations and case scenarios, experience of death and dying, prior knowledge of DNR and basic demographic data were evaluated.Results: A total of 766 students participated in the study. There were statistically (...) significant differences in their DNR decisions in various situations between medical and non-medical students, clinical and preclinical students, and between students who had previously experienced death and dying and those who had not. A prior knowledge of DNR significantly affected DNR decision, although 66.4% of non-medical students and 18.7% of medical students had never heard of DNR. 74% of participants from both medical and non-medical fields considered the patient’s own wish as the most important factor that the healthcare team should consider when making DNR decisions. Family wishes might not be decisive on the choice of DNR.Conclusions: Students in medical and non-medical fields held different views on DNR. A majority of participants considered the patient’s own wish as most important in DNR decisions. Family wishes were considered less important than the patient’s own wishes. (shrink)

This note is prompted by a re-reading of the late Professor J. L. Austin's British Academy Lecture of 1956 “Ifs and Cans” and Professor P. H. Nowell-Smith's rejoinder to it. Austin states his topic at the beginning, and though he re-formulates it more precisely later on, it will suffice for my purposes to quote the opening short paragraph. He asks: “Are cans constitutionally iffy? Whenever, that is, we say that we can do something, or could do something, or could have (...) done something, is there an if in the offing—suppressed, it may be, but due nevertheless to appear when we set out our sentence in full or when we give an explanation of its meaning?”. Towards the end of his lecture he states his conclusion concerning the issue, viz. determinism, which is usually prominent at least implicitly in our discussion of such questions, in the following terms: “Determinism, whatever it may be, may yet be the case, but at least it appears not consistent with what we ordinarily say and presumably think.”. (shrink)

Kant est un interlocuteur fréquent et majeur de Hans Jonas. Il l?est assurément en philosophie pratique. Il lui est à la fois un repoussoir et un modèle à cet égard. Le Kant de la première Critique n?est pas non plus absent de l??uvre de Jonas, et il ne l?est pas, en particulier, du Phénomène de la vie , même s?il y est présent de manière assez sporadique. Mais un Kant dont l?absence est notable dans ce projet de biologie (...) philosophique qui entend rétablir, contre les sciences modernes, les droits du concept de finalité, c?est le Kant de la troisième Critique et singulièrement celui qui s?attelle à l?étude du jugement téléologique. Le titre de la Critique de faculté de juger n?est pas mentionné. Cette absence peut faire question et elle donne un angle d?attaque pour interroger le statut du projet jonassien dans le Phénomène de la vie . De manière abrupte : cette absence n?autorise-t-elle pas à penser que le projet est simplement précritique ? Quel autre sens pourrait-on donner à cette absence, et de quels indices dispose-t-on à cet égard ? Détecte-t-on, à seconde vue, une présence implicite de Kant ? On se contentera de poser ici quelques jalons dans l?instruction de ce dossier. Et l?on se gardera bien de prétendre à quelque démonstration que ce soit. Retournons donc à l?énoncé du projet de Jonas, et d?abord, inévitable­ment, à un très bref rappel des thèses kantiennes, pour baliser. (shrink)

8 March, now known as International Women’s Day, is a day for feminist claims where demonstrations are organized in over 150 countries, with the participation of millions of women all around the world. These demonstrations can be viewed as collective rituals and thus focus attention on the processes that facilitate different psychosocial effects. This work aims to explore the mechanisms involved in participation in the demonstrations of 8 March 2020, collective and ritualized feminist actions, and their correlates associated with personal (...) well-being and collective well-being, collective efficacy and collective growth, and behavioral intention to support the fight for women’s rights. To this end, a cross-cultural study was conducted with the participation of 2,854 people from countries in Latin America and Europe, with a retrospective correlational cross-sectional design and a convenience sample. Participants were divided between demonstration participants and non-demonstrators or followers who monitored participants through the media and social networks. Compared with non-demonstrators and with males, female and non-binary gender respondents had greater scores in mechanisms and criterion variables. Further random-effects model meta-analyses revealed that the perceived emotional synchrony was consistently associated with more proximal mechanisms, as well as with criterion variables. Finally, sequential moderation analyses showed that proposed mechanisms successfully mediated the effects of participation on every criterion variable. These results indicate that participation in 8M marches and demonstrations can be analyzed through the literature on collective rituals. As such, collective participation implies positive outcomes both individually and collectively, which are further reinforced through key psychological mechanisms, in line with a Durkheimian approach to collective rituals. (shrink)

This chapter highlighted some salient trends in pediatric ethicsEthics, pediatric from different parts of the globe. It is interesting to note that although diverse, there are many similarities between ethical challenges in pediatrics in different parts of the world.

La presente antología es fruto de la colaboración entre profesores de las Universidades de Paraíba (Brasil) y Jaén (España) y sólo pretende presentar un conjunto de textos extraídos de obras de autores de origen judeoconverso, o vinculados con la antigua Universidad de Baeza (siglos XVI y XVII). En estos fragmentos quedan de manifiesto planteamientos comunes sobre la observación de la naturaleza y el conocimiento, pautas y orientaciones de carácter pedagógico, criterios para la organización del cuerpo social, visión de la espiritualidad, (...) inquietudes por la formación de la mujer, o el problema de la evangelización y adoctrinamiento de los amerindios. (shrink)

The level of development of advertising and sponsorship activities in Russia is still significantly inferior to Western countries, but every year we see tremendous development in this area. Sponsorship is not mostly considered as an investment and marketing communication yet, but rather as a charity. This approach, according to the authors, is more consistent with philanthropy. In this regard, the article defines the concepts of "sponsorship" and "philanthropy", shows the difference between them. Examples of interaction between sports organizations and sponsors (...) are considered. The role of advertising in this interaction is analyzed. According to the authors, Russia has a good legal framework for regulating the relations of sponsors, patrons, athletes and fans, but the system of ethical control of such relations is poorly developed. (shrink)

Objectives To investigate empirically the motivations for not consenting to DNA biobanking in a Swedish population-based study and to discuss the implications. Design Structured questionnaires and semistructured interviews. Setting A longitudinal epidemiological project (PART) ongoing since 1998 in Stockholm, Sweden. The DNA-collection wave took place during 2006–7. Participants 903 individuals completed the questionnaire (participation rate 36%) and 23 were interviewed. All individuals had participated in both non-genetic waves of the project, but refused to contribute saliva samples during the DNA-collection wave. (...) Main outcome measures Motivations behind refusing to consent to DNA biobanking, with subsequent focus on participants' explanations regarding this unwillingness. Results Public refusal to consent to DNA biobanking, as revealed by the questionnaire, was mainly explained by a lack of personal relevance of DNA contribution and feelings of discomfort related to the DNA being used for purposes other than the respective study. Interviews of individuals representing the second motivation, revealed a significant mistrust of DNA biobank studies. The underlying beliefs and attitudes were associated with concerns about integrity, privacy, suspiciousness and insecurity. However, most interviewees were supportive of genetic research per se and interpreted their mistrust in the light of distressing environmental influences. Conclusion The results suggest a need for guidelines on benefit sharing, as well as trustworthy and stable measures to maintain privacy, as a means for increasing personal relevance and trust among potential participants in genetic research. Measures taken from biobanks seem insufficient in maintaining and increasing trust, suggesting that broader societal measures should be taken. (shrink)

Biographie de Joaquin Carreras y Artau.--Biographie de Mgr Juan Tusquets.--Introduction par J. C. A.--Pierre d'Espagne, Pape Jean XXI, par J. Carreras Artau.--Raymond Lulle, un logicien et encyclopédiste du XIIIe siècle, par J. Carreras Artau.--Louis Vives, philosophe de l'humanisme, par J. Carreras Artau.--François Suárez, sa métaphysique et sa critériologie, par J. Tusquets.--Jaime Balmes, son système philosophique, par J. Tusquets.--Les contemporaíns (Zaragüeta, Zubiri, D'Ors, Muñoz Alonso), par J. Tusquets.

Although activated spinal cord glia contribute importantly to neuropathic pain, how nerve injury activates glia remains controversial. It has recently been proposed, on the basis of genetic approaches, that toll-like receptor 4 may be a key receptor for initiating microglial activation following L5 spinal nerve injury. The present studies extend this idea pharmacologically by showing that TLR4 is key for maintaining neuropathic pain following sciatic nerve chronic constriction injury. Established neuropathic pain was reversed by intrathecally delivered TLR4 receptor antagonists derived (...) from lipopolysaccharide. Additionally, -naltrexone, -naloxone, and -naloxone, which we show here to be TLR4 antagonists in vitro on both stably transfected HEK293-TLR4 and microglial cell lines, suppressed neuropathic pain with complete reversal upon chronic infusion. Immunohistochemical analyses of spinal cords following chronic infusion revealed suppression of CCI-induced microglial activation by -naloxone and -naloxone, paralleling reversal of neuropathic pain. Together, these CCI data support the conclusion that neuron-to-glia signaling through TLR4 is important not only for initiating neuropathic pain, as suggested previously, but also for maintaining established neuropathic pain. Furthermore, these studies suggest that the novel TLR4 antagonists -naloxone and -naloxone can each fully reverse established neuropathic pain upon multi-day administration. This finding with -naloxone is of potential clinical relevance. This is because -naloxone is an antagonist that is inactive at the -opioid selective receptors on neurons that produce analgesia. Thus, these data suggest that -opioid antagonists such as -naloxone may be useful clinically to suppress glial activation, yet -opioid agonists suppress pain. (shrink)

Extensive research has demonstrated that rs1360780, a common single nucleotide polymorphism within the FKBP5 gene, interacts with early-life stress in predicting psychopathology. Previous results suggest that carriers of the TT genotype of rs1360780 who were exposed to child abuse show differences in structure and functional activation of emotion-processing brain areas belonging to the salience network. Extending these findings on intermediate phenotypes of psychopathology, we examined if the interaction between rs1360780 and child abuse predicts resting-state functional connectivity (rsFC) between the amygdala (...) and other areas of the salience network. We analyzed data of young European adults from the general population (N = 774; mean age = 18.76 years) who took part in the IMAGEN study. In the absence of main effects of genotype and abuse, a significant interaction effect was observed for rsFC between the right centromedial amygdala and right posterior insula (p <.025, FWE-corrected), which was driven by stronger rsFC in TT allele carriers with a history of abuse. Our results suggest that the TT genotype of rs1360780 may render individuals with a history of abuse more vulnerable to functional changes in communication between brain areas processing emotions and bodily sensations, which could underlie or increase the risk for psychopathology. (shrink)

Kur’ân’da, bazı eylemlerin iyi amelleri düşüreceği (iptal edeceği) bildirilir. Bu eylemler ayetlerde ‘Habtu’l- a’mâl/ İhbâtu’l- ama’l’ formatıyla ele alınır. Bu ayetlerde vurgu yapılan ortak temel nokta, salih amellerin (iyi eylemlerin) kötü eylemler ile düşürülmesi hadisesidir. İşte bu makalede, konu ile ilgili şu sorulara cevap aranacaktır: İyi ameller ve kötü ameller nelerdir? Onların düşme (bâtıl olma) keyfiyeti nedir? Hangi eylemler iyi amelleri düşürür? Bu ameller dünyada mı ahirette mi düşer?

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

Les parallèles présentés dans l’article entre théologie des Pères et philosophie contemporaine, de Grégoire de Nysse et Jean Chrysostome à Wittgenstein et Jonas, visent à souligner combien les catégories de l’incompréhensible et de l’ineffable constituent de manière récurrente des pierres d’achoppement. La question de Dieu y est évidemment liée, ce qui n’est pas sans faire place, chez les Pères, à l’articulation paradoxale d’un discours où Dieu, dans sa bienveillante Providence, châtie, rétribue, soutient dans l’épreuve, et d’une théologie négative, d’« (...) un temps pour se taire ». (shrink)

Background Residual dried blood spots (rDBS) from newborn screening programmes represent a valuable resource for medical research, from basic sciences, through clinical to public health. In Hong Kong, there is no legislation for biobanking. Parents’ view on the retention and use of residual newborn blood samples could be cultural-specific and is important to consider for biobanking of rDBS. Objective To study the views and concerns on long-term storage and secondary use of rDBS from newborn screening programmes among Hong Kong Chinese (...) parents. Methods A mixed-method approach was used to study the views and concerns on long-term storage and secondary use of rDBS from newborn screening programmes among Hong Kong Chinese parents of children 0–3 years or expecting parents through focus groups (8 groups; 33 participants) and a survey (n = 1012, 85% mothers) designed with insights obtained from the focus groups. We used framework analysis to summarise the themes as supportive factors, concerns and critical arguments for retention and secondary use of rDBS from focus group discussion. We used multiple logistic regression to assess factors associated with support for retention and secondary use of rDBS in the survey. Results Both in focus groups and survey, majority of parents were not aware of the potential secondary use of rDBS. Overall secondary use of rDBS in medical research was well accepted by a large proportion of Hong Kong parents, even if all potential future research could not be specified in a broad consent. However parents were concerned about potential risks of biobanking rDBS including leaking of data and mis-use of genetic information. Parents wanted to be asked for permission before rDBS are stored and mainly did not accept an “opt-out” approach. The survey showed that parents born in mainland China, compared to Hong Kong born parents, had lower awareness of newborn screening but higher support in biobanking rDBS. Higher education was associated with support in rDBS biobanking only among fathers. Conclusion Long-term storage and secondary use of rDBS from newborn screening for biomedical research and a broad consent for biobanking of rDBS are generally acceptable to Hong Kong parents given their autonomy is respected and their privacy is protected, highlighting the importance of an accountable governance and a transparent access policy for rDBS biobanks. (shrink)

The quantum mechanical description of the evolution of an unstable system defined initially as a state in a Hilbert space at a given time does not provide a semigroup (exponential) decay, law. The Wigner–Weisskopf survival amplitude, describing reversible quantum transitions, may be dominated by exponential type decay in pole approximation at times not too short or too long, but, in the two channel case, for example, the pole residues are not orthogonal, and the evolution does riot correspond to a semigroup (...) (experiments on the decay of the neutral K-meson system strongly support the semigroup evolution postulated, by Lee, Oehme and Yang, and Yang and Wu). The scattering theory of Lax and Phillips, originally developed for classical wave equations, has been recently extended to the description of the evolution of resonant states in the framework of quantum theory. The resulting evolution law of the unstable system is that of a semigroup, and the resonant state is a well-defined function in the Lax–Phillips Hilbert space. In this paper we apply this theory to a relativistically covariant quantum field theoretical form of the (soluble) Lee model. We construct the translation representations with the help of the wave operators, and show that the resulting Lax–Phillips S-matrix is an inner function (the Lax–Phillips theory is essentially a theory of translation invariant subspaces). In the special case that the S-matrix is a rational inner function, we obtain the resonant state explicitly and analyze its particle (V, N, θ) content. If there is an exponential bound, the general case differs only by a so-called trivial inner factor, which does not change the complex spectrum, but may affect the wave function of the resonant state. (shrink)

S’inscrivant dans le cadre des récentes tentatives de redécouverte et de réhabilitation historique et littéraire du XIXe siècle haïtien, cet article vise à explorer l’expression de l’universalisme révolutionnaire chez les poètes haïtiens du XIXe siècle, en offrant une nouvelle perspective sur leur utilisation de l’imagerie classique. En particulier, il s’agira de reconsidérer la réception de ces poètes pour révéler la profondeur idéologique souvent ignorée de leurs écrits, enracinés dans les valeurs républicaines des Lumières. En réponse aux accusations racistes de la (...) Métropole – qui réduisent l’insurrection qui a conduit à la déclaration d’indépendance du pays en 1804 à une question de race –, les poètes haïtiens adoptent dans leurs œuvres en vers un imaginaire épique et nationaliste, revendiquant une filiation explicite avec l’universalisme de la Révolution française. Cet imaginaire n’est pas un simple emprunt stylistique, mais une adhésion convaincue aux idéaux universels de la République, ainsi qu’un témoignage du rôle actif des intellectuels haïtiens dans le débat international sur l’abolition de l’esclavage. L’étude proposée ici partira de la contextualisation historico-politique dans laquelle la poésie nationale haïtienne est née et s’est développée, pour se concentrer ensuite sur l’analyse de l’iconographie révolutionnaire de la première production poétique haïtienne. (shrink)

Entre los filósofos contemporáneos que más han hecho por el desarrollo y la consolidación académica de la historia del pensamiento español, destaca la figura de José Luis Abellán. Este libro, escrito por algunos de los más importantes especialistas en esta disciplina, pretende clarificar críticamente la obra de Abellán y recorrer algunos de los temas a los que mayor relevancia ha concedido el autor de la vasta e imprescindible "Historia crítica del pensamiento español". El erasmismo, el mito de Cristo, la generación (...) del 98, Ortega y Gasset y sus discípulos o el exilio del siglo veinte, son algunos de los temas abordados por los autores del libro, y sobre los que José Luis Abellán nos ha ofrecido artículos y monografías imprescindibles para conocer la historia de la filosofía española. (shrink)