What does it mean to understand something? What types of understanding can be distinguished? Is understanding always provided by explanations? And how is it related to knowledge? Such questions have attracted considerable interest in epistemology recently. These discussions, however, have not yet engaged insights about explanations and theories developed in philosophy of science. Conversely, philosophers of science have debated the nature of explanations and theories, while dismissing understanding as a psychological by-product. In this book, epistemologists and philosophers of science together (...) address basic questions about the nature of understanding, providing a new overview of the field. False theories, cognitive bias, transparency, coherency, and other important issues are discussed. Its 15 original chapters are essential reading for researchers and graduate students interested in the current debates about understanding. (shrink)

The auditory system is able to recognize auditory objects and is thought to form predictive models of them even though the acoustic information arriving at our ears is often imperfect, intermixed, or distorted. We investigated implicit regularity extraction for acoustically intact versus disrupted six-tone sound patterns via event-related potentials. In an exact-repetition condition, identical patterns were repeated; in two distorted-repetition conditions, one randomly chosen segment in each sound pattern was replaced either by white noise or by a wrong pitch. In (...) a roving-standard paradigm, sound patterns were repeated 1–12 times in a row before a new pattern occurred. The participants were not informed about the roving rule and had to detect rarely occurring loudness changes. Behavioral detectability of pattern changes was assessed in a subsequent behavioral task. Pattern changes elicited mismatch negativity and P3a, and were behaviorally detected above the chance level in all conditions, suggesting that the auditory system extracts regularities despite distortions in the acoustic input. However, MMN and P3a amplitude were decreased by distortions. At the level of MMN, both types of distortions caused similar impairments, suggesting that auditory regularity extraction is largely determined by the stimulus statistics of matching information. At the level of P3a, wrong-pitch distortions caused larger decreases than white-noise distortions. Wrong-pitch distortions likely prevented the engagement of restoration mechanisms and the segregation of disrupted from true pattern segments, causing stronger informational interference with the relevant pattern information. (shrink)

On peut considérer que ce qui se produit dans le travail familial thérapeutique avec une famille dans une institution donnée est révélateur du fonctionnement de la famille tel que cette dernière le projette sur l’institution. Mais ce qui se passe dans cette thérapie peut aussi refléter le fonctionnement de l’institution à ce moment précis : ce qui se vit dans l’institution a souvent des répercussions sur les prises en charge thérapeutiques.

To help academic and non-profit investigators interested in drug repurposing navigate regulatory approval processes, we compared pathways for repurposed drugs to obtain approval at EMA, UK MHRA, and the US FDA. Though we found no pathways specifically for repurposed drugs, pathways to market are available in all repurposing scenarios.

Das Sammelwerk legt umfassend den Stand der Staatstheorie dar und arbeitet die Beiträge der bedeutendsten Staatsdenker und der wichtigsten Strömungen des Staatsdenkens zum heutigen Staatsverständnis exemplarisch heraus.Renommierte Philosophen, Historiker, Sozial-, Kultur- und Rechtswissenschaftler aus Universitäten und Forschungseinrichtungen in ganz Europa stellen in 15 gleichgewichteten Kapiteln das Staatsdenken von der Antike bis zur Postdemokratie facettenreich heraus. Jedes Kapitel firmiert unter einem Schwerpunkt, angefangen beim klassischen und konservativen über das liberale und feministische bis hin zum anarchistischen und religiösen Staatsdenken. Einen besonderen Stellenwert (...) nimmt dabei das Staatsdenken in anderen Kulturen ein, darunter China, Indien, die arabische Welt sowie das vor- und das postkoloniale Afrika.Die Schlussbetrachtung zum "Staat der Zukunft" bilanziert die Probleme von Souveränitätsverlust, Staatszerfall und Postdemokratie vor dem Hintergrund von Globalisierung, Ökonomisierung und Individualisierung.Praktische Querverweise und ein umfassendes Literaturverzeichnis erleichtern den Zugriff, detaillierte Stichwort- und Personenregister runden das Werk ab.Mit Beiträgen von:Helga Albrecht, Andreas Anter, Olaf Asbach, Friedrich Balke, Ernst Baltrusch, Michael Becker, Hannah Bethke, Karl-Heinz Breier, Michael Brie, Norbert Campagna, Lars Distelhorst, Sabine Doyé, Dominik Finkelde, Oliver Flügel-Martinsen, Alexander Gantschow, Eva Geulen, Gerhard Göhler, Dieter Grimm, Martin Gronau, Gregor Hain, Hendrik Hansen, Leonhard Harding, Oliver Hidalgo, Wilhelm Hofmann, Frauke Höntzsch, Dana Ionescu, Matthias Jestaedt, Dirk Jörke, John Kannankulam, Stefan Koslowski, Oliver W. Lembcke, Rochus Leonhardt, Roland Lhotta, Mathias Lindenau, Marion Löffler, Gundula Ludwig, Günter Maschke, Jean-Christophe Merle, Dominique Fabian Miething, Andreas Niederberger, Claudia Opitz-Belakhal, Henning Ottmann, Gregor Paul, Thore Prien, Walter Reese-Schäfer, Claudia Ritzi, Samuel Salzborn, Stefano Saracino, Birgit Sauer, Peter Seyferth, Thomas Schölderle, Hans-Martin Schönherr-Mann, Ulrich Seeber, Veith Selk, Harald Sippel, Tine Stein, Kazuhiro Takii, Ulrich Thiele, Andreas Vasilache, Rüdiger Voigt, Christian Wendt, Stefanie Wöhl, Joachim Wurst, Holger Zapf und Barbara Zehnpfennig. (shrink)

The ability to be creative is often considered a unique characteristic of conscious beings and many efforts have been directed at demonstrating a relationship between creativity and the personality construct of psychoticism. The present study sought to investigate this link explicitly by focusing on discrete facets of creative cognition, namely the originality/novelty dimension and the practicality/usefulness dimension. Based on Eysenck’s conceptualisation of psychoticism as being characterised by an overinclusive cognitive style, it was expected that higher levels of psychoticism would accompany (...) a greater degree of conceptual expansion and elevated levels of originality in creative imagery, but would be unrelated to the practicality/usefulness of an idea. These hypotheses were confirmed in 80 healthy participants who were contrasted based on their EPQ psychoticism scale scores. Our findings suggest that the link between psychoticism and creativity is based on associative thinking and broader but weak top-down activation patterns rather than on goal-related thinking. (shrink)

Was sind 'äußere' und 'innere' Bilder? Wie entstehen sie? Was sind ihre Korrelate? Seit der Antike bewegen diese Fragen Philosophie, Rhetorik, Literatur- und Kunstwissenschaft, gegenwärtig auch die Medien- und Intermedialitätsforschung und Neurowissenschaften. Als Beitrag zu Bild- und Literaturwissenschaften sowie Visual Studies bietet der Band interdisziplinäre Untersuchungen der Bewegung vom Sehen über das An-schauen zu Anschaulichkeit und Anschauung. Die Beiträge zeigen Verflechtungen zwischen Epistemologie und Ästhetik auf, erhellen Fragen von Imagination und Stil, stellen neue Bezüge zwischen unterschiedlichen Künsten, Medien und Ausdrucks-formen (...) her und bieten neue Einsichten in die visuell-imaginativen Dimensionen von Wissen, Erkenntnis und Erfahrung. (shrink)

Artificial agents are progressively becoming more present in everyday-life situations and more sophisticated in their interaction affordances. In some specific cases, like Google Duplex, GPT-3 bots or Deep Mind’s AlphaGo Zero, their capabilities reach or exceed human levels. The use contexts of everyday life necessitate making such agents understandable by laypeople. At the same time, displaying human levels of social behavior has kindled the debate over the adoption of Dennett’s ‘intentional stance’. By means of a comparative analysis of the literature (...) on robots and virtual agents, we defend the thesis that approaching these artificial agents ‘as if’ they had intentions and forms of social, goal-oriented rationality is the only way to deal with their complexity on a daily base. Specifically, we claim that this is the only viable strategy for non-expert users to understand, predict and perhaps learn from artificial agents’ behavior in everyday social contexts. Furthermore, we argue that as long as agents are transparent about their design principles and functionality, attributing intentions to their actions is not only essential, but also ethical. Additionally, we propose design guidelines inspired by the debate over the adoption of the intentional stance. (shrink)

This essay presents an account of what it takes to live a philosophical way of life: practitioners must be committed to a worldview, structure their lives around it, and engage in truth‐directed practices. Contra John Cooper, it does not require that one’s life be solely guided by reason. Religious or tradition‐based ways of life count as truth directed as long as their practices are reasons responsive and would be truth directed if the claims made by their way of life are (...) correct. The essay argues that these three conditions can be met by progressors as well as sages. Making progress in how one acts in the world, and improving one’s understanding and direction through being part of a community is living a philosophical way of life. The offered view acknowledges more ways to develop the art of living and enables a broader range of people to count as living philosophically. (shrink)

In this paper, we analyse the Wittgensteinian critique of the orthodoxy in animal ethics that has been championed by Cora Diamond and Alice Crary. While Crary frames it as a critique of “moral individualism”, we show that their criticism applies most prominently to certain forms of moral individualism (namely, those that follow hedonistic or preference-satisfaction axiologies), and not to moral individualism in itself. Indeed, there is a concrete sense in which the moral individualistic stance cannot be escaped, and we believe (...) that it is this particular limitation that justified Crary’s later move to a qualified version of moral individualism. At the same time, we also argue that there are significant merits to the Wittgensteinian critique of moral individualism, which pertain to its attack on the rationalism, naturalism, and reductionism that characterise orthodox approaches to animal ethics. We show that there is much of value in the Wittgensteinians’ call for an ethics that is more human; an ethics that fully embraces the capacities we are endowed with and one that pays heed to the richness and complexity of our moral lives. (shrink)

Capacity : environment in a century of space -- Containment : the ship as a figure of enclosure and expansion -- Circulation : ecological life support systems -- Storage : the lifeboats of human ecology -- Classification : biosphere reserves -- Departure : the habitats of tomorrow.

It is well documented that the language skills of preschool children differ substantially and that these differences are highly predictive of their later academic success and achievements. Especially in the early phases of children’s lives, the importance of different structural and process characteristics of the home learning environment (HLE) has been emphasized and research results have documented that process characteristics such as the quality of parental interaction behavior and the frequency of joint activities vary according to the socio-economic status (SES) (...) of the family. Further, both structural and process characteristics are associated with children’s language development. As most of the studies focus on single indicators or didn’t take the dynamics of parenting behavior across age into account, the present paper aims to investigate the associations of different characteristics of the home learning environment as well as their potentially changing impact on the language skills of 2-year-old children. Using data of 2.272 families of the infant cohort study of the German National Educational Panel Study (NEPS), longitudinally assessed process characteristics (sensitivity in the sense of maternal responsivity to the child’s behavior and signals in mother–child interaction; maternal stimulation behavior which goes beyond the child’s actual level of action and development; frequency of joint picture book reading) and structural characteristics (mother’s education, equivalised household income, parental occupational status) were considered. Language skills (vocabulary and grammar) of the children at the age of two were measured by a standardized and validated parent report instrument (child language checklist). Results showed that (1) all three process characteristics of the home learning environment (HLE) are associated with the family’s SES; (2) across three assessment waves nearly all process characteristics predicted children’s vocabulary and grammar skills with some process-specific changes across waves; (3) despite separate direct effects of nearly all HLE-process characteristics in each wave, the amount of explained variance in a joint model including the HLE facets from each wave is hardly higher than in the separate models; and (4) socioeconomic background predicted both language facets of the children in each model even when controlling for the assessed process characteristics of the home learning environment. (shrink)

Direct-to-consumer genetic testing has been available for several years now, with varying degrees of regulation across different countries. Despite a restrictive legal framework it is possible for consumers to order genetic tests from companies located in other countries. However, German laypeople’s awareness and perceptions of DTC GT services is still unexplored. We conducted seven focus groups with German laypeople to explore their perceptions of and attitudes towards commercial genetic testing and its ethical implications. Participants were critical towards DTC GT. Criticism (...) was directed at health-related, predictive testing, while lifestyle tests were accepted and even welcomed to some extent. Participants expressed strong reservations regarding commercial provision of genetic diagnostics and expressed a lack of trust in respective companies. They preferred non-commercial distribution within the public healthcare system. Participants also expressed high expectations of physicians’ abilities to interpret information obtained via DTC GT companies and provide counseling. Legal restrictions on commercial distribution of genetic tests were opposed, with participants arguing that it should be available to consumers. DTC GT companies are not perceived as trustworthy when compared to the public healthcare system and its professional ethical standards and practices. Laypeople rated general consumer autonomy higher than their own concerns, thus recommending against strong legal regulation. We conclude that medicine’s trustworthiness may be negatively affected if commercial provision is not visibly opposed by the medical professions, while DTC GT companies may gain in trustworthiness if they adapt to standards and practices upheld in medicine. (shrink)

Im Zuge des „empirical turn“ der Medizin- und Bioethik ist von verschiedenen Autoren in den vergangenen Jahren die Idee einer „evidenzbasierten Ethik“ diskutiert worden. Die Analogie zwischen evidenzbasierter Medizin und „evidenzbasierter Ethik“ soll in diesem Beitrag kritisch diskutiert und dabei gezeigt werden, dass der Ausdruck „evidenzbasierte Ethik“ irreführend ist. Zentraler Ausgangspunkt der Kritik ist die unterschiedliche Bedeutung, die empirische Informationen für das medizinisch-klinische Urteil zum einen und das ethische Urteil in der Medizin zum anderen haben. Im medizinisch-klinischen Urteil können mit (...) Hilfe empirischer Informationen hypothetische Handlungsnormen generiert werden, welche auf den der Medizin inhärenten Zwecksetzungen basieren. Bei Fragen der Ethik in der Medizin hingegen sind die Handlungsziele selbst Gegenstand des Urteils; diese aber können allein aus empirischem Wissen heraus nicht zureichend bestimmt werden. Die Diskussion um die Möglichkeit einer „evidenzbasierten Ethik“ eröffnet weiterhin aufschlussreiche Perspektiven in Bezug auf empirische Forschung und den Umgang mit empirischen Informationen in der Angewandten Ethik und das Aufgabenfeld der Medizinethik. (shrink)

ZusammenfassungIm Spielfilm Never Let Me Go werden Klone als vulnerable und heteronome Individuen dargestellt, die zur anonymen Organspende gezwungen werden. In diesem Beitrag wird die Darstellung dieser Figuren in ihrer individuellen Entwicklung und gesellschaftlichen Sozialisation unter der Frage untersucht, welche Bezüge sich zu bioethischen Aspekten ergeben. Die Klone befinden sich in einer Situation der „privilegierten Deprivation“: Aus Sicht der Zuschauer sind sie sozial benachteiligt und können sich nicht zu komplett autonomen Wesen entwickeln, aber aus ihrer eigenen Perspektive sind sie im (...) dystopischen System immer noch „privilegiert“. Wir argumentieren, dass dieser Film auf symbolische Weise diejenigen Individuen fokussiert, die vom medizinischen Fortschritt nicht profitieren oder die nicht genügend Handlungsspielraum haben, um sich gegen geltende Praxen zu positionieren. Filme wie Never Let Me Go können deshalb ein Beitrag sein, um die Perspektive marginalisierter Personen im medizinischen System einzunehmen. (shrink)

Embodied Fantasies: From Awe to Artifice is a compilation of twenty-one essays on the subject of fantasy as it relates to art history, philosophy and the visual arts.

Nature, a topic central to art history, is concurrently a dominant concept in contemporary art, art theory and its related disciplines such as cultural theory, philosophy, aesthetic theory and environmental studies. The project Naturally Hypernatural questions lines of tradition and predetermined categories that coexist with the topic of nature. Currently, nature in art surpasses the simple depiction of art as a material or object. To clarify and analyze the interrelations between nature and art is the aim of the project Naturally (...) Hypernatural. Concepts of Nature - the first volume of this project - argues that contemporary art is predominantly concerned with concepts of nature regarding the depth of their implications in order to reveal and analyze their internal structure. (shrink)

YVES CHARLES ZARKA ET SABINE CHOQUET. — Est-ce qu’il y a un acte de naissance du souverainisme au Québec ? Et, si tel est le cas, est-il lié à la visite du général de Gaulle au Québec et à la célèbre phrase : « Vive le Québec libre ! » qu’il a prononcée à Montréal le 24 juillet 1967 ?JOSEPH FACAL. — On..

YVES CHARLES ZARKA ET SABINE CHOQUET. — Est-ce qu’il y a un acte de naissance du souverainisme au Québec ? Et, si tel est le cas, est-il lié à la visite du général de Gaulle au Québec et à la célèbre phrase : « Vive le Québec libre ! » qu’il a prononcée à Montréal le 24 juillet 1967 ?JOSEPH FACAL. — On..

At the same time new versions of foundationalism were crafted, that were claimed to be immune to the earlier criticisms. This volume contains 12 papers in which various aspects of this dialectic are covered.

The excavations carried out beside the north rampart of the lower town of Amathus have revealed the existence of a large archaic deposit, most probably originating from a destruction of the palace on the acropolis. This is the first part of a series of articles devoted to the material from this deposit. It deals with the context of its discovery, and considers the circular structure, which requires careful attention, filled by this material.

Die Autorin geht der Frage nach, welche Raum- und Ortskonzeptionen in den 1990er Jahren - nach der kritischen Relektüre der Ortspezifik - in der Kunst Verwendung gefunden haben. Dabei erweist sich "The Ambient" als Schlüsselphänomen. Ursprünglich für die Musik entwickelt, ist das Konzept des "Ambient" durch die Konstruktion eines vorübergehenden, prozessualen Ortes gekennzeichnet. Hergestellt wird dieser einerseits durch künstlerische Produktionsprozesse, die in bestehende Architektur- und Landschaftsräume verändernd eingreifen. Andererseits basiert "Ambient" auf kollektiven Praktiken. Sabine Gebhardt Fink erläutert, wie die (...) ortspezifische Kunst der 1960er Jahre weiterentwickelt wurde. Sie beschreibt spezifische Formen immersiven ästhetischen Erlebens und beleuchtet den Einfluss des Ortskonzeptes von Ambient Music und Ambient Sound. Anhand künstlerischer Projekte von Ricardo Basbaum, Janet Cardiff, Alice Creischer / Andreas Siekmann / Christian von Borries, Thomas Hirschhorn, San Keller und Hendrikje Kühne / Beat Klein wird schließlich geklärt, was unter einer Ästhetik des Mit-Seins zu verstehen ist. (shrink)

Name der Zeitschrift: Frühmittelalterliche Studien Jahrgang: 36 Heft: 2 Seiten: 243-250.

Comment expliquer que les savoirs de sciences humaines et sociales soient à ce point contestés voire ignorés dans les lieux où ils pourraient pourtant éclairer la réflexion et l'action? Comment expliquer la défiance et l'incompréhension qu'ils suscitent parfois? Les savoirs de sciences humaines et sociales ont la particularité de circuler dans des espaces variés et de devoir composer avec une critique prompte à remettre en cause leur validité et leur légitimité. Leur acceptabilité sociale ne se joue pas dans la seule (...) communauté savante mais bien dans les multiples réinterprétations et traductions auxquelles ils donnent lieu. Les études réunies dans ce volume analysent sept controverses ayant pour enjeu le sort réservé à des savoirs issus de la réflexion philosophique, sociologique, psychologique ou se revendiquant d'une économie hétérodoxe. Elles montrent que les résistances qu'ils rencontrent sont la marque paradoxale de leur vigueur et de leur capacité à bousculer les évidences partagées. Contributeurs : Elisabeth Chatel, Sandra Laugier, Frédéric Lebaron, Alexandra Oeser, Etienne Penissat, Sophie Richardot, Sabine Rozier. (shrink)

Assuming GCH, we prove that for every successor cardinal μ > ω1, there is a superatomic Boolean algebra B such that |B| = 2μ and |Aut B| = μ. Under ◊ω1, the same holds for μ = ω1. This answers Monk's Question 80 in [Mo].

Die Einführung der Fallpauschalen-basierten Finanzierung der Krankenhäuser ist ein erneuter Versuch, die Kosten in diesem Bereich zu reduzieren. Folge dieses Anreizsystems ist u. a. eine deutliche Verkürzung der Verweildauer der Patienten im Krankenhaus. Das wiederum führt zu durchschnittlich kränkeren Patienten und einer deutlichen Arbeitsverdichtung für alle. Vor diesem Hintergrund wird anhand empirischer Daten die Situation der Pflege mit drastischen Einschränkungen beschrieben und es werden Hypothesen zur Begründung aufgestellt. Daran knüpft sich die Frage, welche Art der Versorgung die Patienten mit kürzer (...) werdender Verweildauer und immer häufiger auftretenden chronischen Krankheiten neben der ärztlichen Therapie benötigen. Dies baut auf der Theorie der Aufgaben zur Krankheitsbewältigung auf, die Patienten befähigen sollen, mit Krankheiten in ihrem eigenen Sinne umgehen zu können. Die Kernaufgaben der Pflege werden hier mit dem Ziel der forcierten Förderung der Entlassungsfähigkeit verbunden mit einem Empowerment der Patienten verknüpft. Organisatorisch bietet sich als Lösung der Einsatz von Primary Nurses an. Die derzeitige Situation in der Pflege widerspricht den genannten Sollvorstellungen diametral. Im Sinne einer sicheren und effektiven Versorgung von Patienten im Krankenhaus muss der Pflegedienst inhaltlich völlig anders aufgestellt und mit weiteren Kompetenzen ausgestattet werden. (shrink)

In this article, from the 2009 Oxford University Press collection Epistemic Value, I criticize existing accounts of epistemic normativity by Alston, Goldman, and Sosa, and then offer a new view.

According to ‘orthodox’ epistemology, it has recently been said, whether or not a true belief amounts to knowledge depends exclusively on truth-related factors: for example, on whether the true belief was formed in a reliable way, or was supported by good evidence, and so on. Jason Stanley refers to this as the ‘intellectualist’ component of orthodox epistemology, and Jeremy Fantl and Matthew McGrath describe it as orthodox epistemology’s commitment to a ‘purely epistemic’ account of knowledge — that is, an account (...) of knowledge where only truth-related factors figure in whether or not a person knows. In the first part of this paper I try to clarify the intellectualist thesis and to distinguish what I take to be its two main strains. In the remainder of the paper I then take a more critical turn and argue that even if, as a matter of fact, traditional epistemology has endorsed intellectualism in both of its strains, this is a mistake on the part of the tradition. At least one way of understanding intellectualism should be rejected and its practicalist counterpart should be accepted instead. (shrink)

Defenders of pragmatic encroachment in epistemology (or what I call practicalism) need to address two main problems. First, the view seems to imply, absurdly, that knowledge can come and go quite easily—in particular, that it might come and go along with our variable practical interests. We can call this the stability problem. Second, there seems to be no fully satisfying way of explaining whose practical interests matter. We can call this the “whose stakes?” problem. I argue that both problems can (...) be addressed in roughly the same terms. More exactly, I argue that by first clarifying the whose stakes? problem an answer to the stability problem naturally falls out. (shrink)