This essay explores the use of stringed instruments (and in particular the harpsichord) as models of brain and cognitive function in eighteenth-century French medicine and natural philosophy. These comparisons were founded in part on the anatomical investigations of the latter half of the seventeenth century, which had established both the “fibrous” structure of the white and gray matter of the cerebrum and the vibratory movement the brain underwent in the performance of its functions. Musical instruments—and in particular the harpsichord—helped these (...) philosophers speculate about how the brain worked as the material instrument of sensation and thought: they were machines at once mechanical and affective, grounded in the materiality of their wooden boards and metal strings, yet symbolizing the rational—and immaterial—harmonies of music. (shrink)

PACKAGE THIS TITLE WITH OUR 2016 MLA SUPPLEMENT, Documenting Sources in MLA Style (package ISBN-13: 9781319084387). Get the most recent updates on MLA citation in a convenient, 40-page resource based on The MLA Handbook, 8th Edition, with plenty of models. Browse our catalog or contact your representative for a full listing of updated titles and packages, or to request a custom ISBN. The unique collaborative effort of a professor of English and a professor of philosophy, Current Issues and Enduring Questions (...) is an extensive resource for teaching argument, persuasive writing, and rigorous critical thinking. This extraordinarily versatile text and reader continues to address current student interests and trends in argument, research, and writing.Its comprehensive coverage of classic and contemporary approaches to argument includes Aristotelian, Toulmin, and a range of alternative views, including a new chapter on analyzing and writing about arguments in popular culture. Readings on contemporary controversies (including student loan debt, locavorism, and the boundaries of online privacy) and classical philosophical questions (such as How free is the will of the individual?) are sure to spark student interest and lively discussion and writing, and new e-Pages take advantage of what the Web can do by including videos, speeches, film trailers, and other multimodal arguments. (shrink)

Black Africans who were brought to Cuba as slaves represented a variety of origins and belonged to linguistic groups that were as divergent as their cultural backgrounds. A huge majority, however, originated in the Congo basin. The last officially recorded arrival of a slave ship in a Cuban port took place in 1873.It would be impossible to classify expressions of Bantu origin that were used in the slave trade. The arbitrary label “Congo” has been applied to most such expressions with (...) a view to noting and suggesting a kinship with the cultural and religious heritage branching off from the Bantu linguistic trunk. (shrink)

Ivan Illich, philosopher, historian, priest and social commentator died in Bremen, Germany on December 2, 2002. Illich was noted for his critique of the Church, education and medicine but his concepts dealt with more fundamental issues. This article reveals aspects of Illich, the man, and explores his ideas as they apply to the meaning of medicine and, in particular, the role of health care in contemporary society.

"Critical Thinking, Reading, and Writing" is a compact but thorough guide to critical thinking and argumentation. Comprising the text portion of the widely adopted "Current Issues and Enduring Questions," it draws on the authors' dual expertise in effective persuasive writing and rigorous critical thinking. It helps students move from critical thinking to argumentative and researched writing. With comprehensive coverage of classic and contemporary approaches to argument, including Aristotle, Toulmin, and a range of alternative views, it is an extraordinarily versatile text. (...) This affordable guide can stand alone or supplement a larger anthology of readings. "Critical Thinking, Reading, and Writing" has been revised to address current student interests and trends in argument, research, and writing. (shrink)

In response to requests for briefer and less expensive argument readers, Contemporary & Classic Arguments offers an ample selection of readings in a compact size for less than half the price of full size books. Contemporary & Classic Arguments is flexibly organized into two anthologies that model an extensive range of argumentative writing. Adapted from the best-selling full-size argument text/reader Current Issues & Enduring Questions, it offers two brief chapters on analyzing and writing arguments, a provocative selection of contemporary arguments (...) and casebooks to engage students with some of today’s most pressing topics, and a collection of classic essays that provide time-tested models of effective argument. Like other volumes in the Bedford/St. Martin’s popular series of Portable Anthologies and Portable Guides, Contemporary & Classic Arguments offers the series’ trademark combination of high quality and great value for teachers of writing and their cost-conscious students. (shrink)

PACKAGE THIS TITLE WITH OUR 2016 MLA SUPPLEMENT, Documenting Sources in MLA Style (package ISBN-13: 9781319084387). Get the most recent updates on MLA citation in a convenient, 40-page resource based on The MLA Handbook, 8th Edition, with plenty of models. Browse our catalog or contact your representative for a full listing of updated titles and packages, or to request a custom ISBN. The unique collaborative effort of a professor of English and a professor of philosophy, Current Issues and Enduring Questions (...) is an extensive resource for teaching argument, persuasive writing, and rigorous critical thinking. This extraordinarily versatile text and reader continues to address current student interests and trends in argument, research, and writing.Its comprehensive coverage of classic and contemporary approaches to argument includes Aristotelian, Toulmin, and a range of alternative views, including a new chapter on analyzing and writing about arguments in popular culture. Readings on contemporary controversies (including student loan debt, locavorism, and the boundaries of online privacy) and classical philosophical questions (such as How free is the will of the individual?) are sure to spark student interest and lively discussion and writing, and new e-Pages take advantage of what the Web can do by including videos, speeches, film trailers, and other multimodal arguments. (shrink)

Cancer cells seem to exploit mechanisms that evolve as part of physiological tolerance, which is a complementary and often beneficial form of defense. The study of physiological systems of tolerance can therefore provide insights into the development of a state of host tolerance of cancer, and how to break it. Analysis of these models has the potential to improve our understanding of existing immunological therapeutic targets, and help to identify future targets and rational therapeutic combinations. The treatment of cancer with (...) immune checkpoint inhibitors aims to reverse the progression to tolerance of cancer, and achieve an immunogenic, rather than tolerogenic, homeostasis. Broadening the efficacy and durability of checkpoint inhibitors focuses on reversing tolerance and stimulating immunogenicity in the cancer, host, and environment. Two examples of important physiological states of tolerance that may inform tolerance of cancer are microbial infection and placental reproduction. These states of tolerance result from bilateral shaping of host and non‐self, akin to immunoediting in cancer, and offer reliable models to study the immune tolerance paradigm. (shrink)

One of the most problematic aspects of the ‘Harvard School’ of liberal international theory is its failure to fulfil its own methodological ideals. Although Harvard School liberals subscribe to a nomothetic model of explanation, in practice they employ their theories as heuristic resources. Given this practice, we should expect them neither to develop candidate causal generalizations nor to be value-neutral: their explanatory insights are underpinned by value-laden choices about which questions to address and what concepts to employ. A key question (...) for liberal theorists, therefore, is how a theory may be simultaneously explanatory and value-oriented. The difficulties inherent in resolving this problem are manifested in Ikenberry's writing: whilst his work on constitutionalism in international politics partially fulfils the requirements of a more satisfactory liberal explanatory theory, his recent attempts to develop prescriptions for US foreign policy reproduce, in a new form, key failings of Harvard School realism. (shrink)

We present a mini review of the Stueckelberg mechanism, which was proposed to make the abelian gauge theories massive as an alternative to Higgs mechanism, within the framework of Minkowski as well as curved spacetimes. The higher the scale the tighter the bounds on the photon mass, which might be gained via the Stueckelberg mechanism, may be signalling that even an extremely small mass of the photon which cannot be measured directly could have far reaching effects in cosmology. We present (...) a cosmological model where Stueckelberg fields, which consist of both scalar and vector fields, are non-minimally coupled to gravity and the universe could go through a decelerating expansion phase sandwiched by two different accelerated expansion phases. We discuss also the possible anisotropic extensions of the model. (shrink)