Here we discuss a “chromosome separation checkpoint” that might regulate the anaphase‐telophase transition. The concept of cell cycle checkpoints was originally proposed to account for extrinsic control mechanisms that ensure the order of cell cycle events. Several checkpoints have been shown to regulate major cell cycle transitions, namely at G1‐S and G2‐M. At the onset of mitosis, the prophase‐prometaphase transition is controlled by several potential checkpoints, including the antephase checkpoint, while the spindle assembly checkpoint guards the metaphase‐anaphase transition. Our hypothesis (...) is based on the recently uncovered feedback control mechanism that delays chromosome decondensation and nuclear envelope reassembly until effective separation of sister chromatids during anaphase is achieved. A central player in this potential checkpoint is the establishment of a constitutive, midzone‐based Aurora B phosphorylation gradient that monitors the position of chromosomes along the spindle axis. We propose that this surveillance mechanism represents an additional step towards ensuring mitotic fidelity. (shrink)

This article discusses the function, development and maintenance of meaning and the importance of meaning-making from different perspectives, as it is based on a collaboration between professionals from health science and psychology. The aim is to discuss how meaning-making processes can be employed in the health context to enhance individuals’ well-being. Starting point is a description of the common basis of the understanding of meaning-making. Afterwards brief examples from the different professional areas will show how meaning-making can improve health care (...) practice. We will focus on the processual nature of meaning-making, its existential layers, as well as the ways in which meaning-making is at play in everyday activities and limit situations, such as illness or suicidality. (shrink)

Most studies investigating the relationship between cultural constructs and ethical perception have focused on individual- and societal-level values without much attention to other type of cultural constructs such as social beliefs. In addition, we need to better understand how social beliefs are linked to ethical perception and the level of analysis at which social beliefs may best predict ethical perceptions. This research contributes to the cross-cultural ethical perception literature by examining the relationship of individual-level social cynicism belief, one of five (...) universally endorsed social beliefs, together with individual social dominance orientation and the perception of unethical behavior. By means of two studies, we examine these relationships across societies that significantly differ on societal-level social cynicism belief. Using 371 business students from Russia and the U.S. in Study 1 and 268 professionals from Portugal and the U.S. in Study 2, we found that individual-level social cynicism belief was positively associated with social dominance orientation. Social dominance orientation, in turn, mediated the relationship between individual social cynicism belief and the perception of unethical behavior. Although we found significant societal-level differences in social cynicism belief in both studies, the relationships between individual-level social cynicism belief, social dominance orientation, and the perception of unethical behavior were structurally equivalent across societies in both studies, suggesting that societal-level differences did not significantly affect these relationships. Implications for cross-cultural business ethics research and practice are discussed. (shrink)

We thank Carrie Jenkins and Neil Levy for their thoughtful comments on our article about love and addiction. Although we do not have room for a comprehensive reply, we will touch on a few main issues.Jenkins points out, correctly in our view, that the word ‘addiction’ can trigger “connotations of reduced autonomy.” It may therefore be used, she argues, to “excuse” violent or otherwise harmful behaviors—disproportionately carried out by men—within the context of romantic relationships. Debates about love addiction, therefore, “are (...) best addressed with an eye to the more general issue of how we as a society apportion responsibility for things like date rape and intimate partner violence” (Jenkins... (shrink)

BackgroundSeveral studies identified low subjective feelings of power in women with anorexia nervosa. However, little is known about implicit power motives and the discrepancy between explicit feelings of power and implicit power motives in AN.AimThe study investigated the discrepancy between explicit feelings of power and implicit power motives and its relationship to anxiety in patients with AN.MethodFifty-three outpatients and inpatients with AN and 48 participants without AN were compared regarding subjective feelings of power and anxiety. Explicit power [investigated with the (...) Personal Sense of Power Scale and a visual analog scale ], implicit power motives [investigated with the Multi-Motive Grid ] and trait anxiety [measured with the State-Trait Anxiety Inventory ], were assessed.ResultsExplicit feelings of power were lower in patients with AN compared to non-AN participants. No differences in implicit power motives were found when comparing the groups against each other. However, looking at the groups separately, women with AN had similar levels of implicit fear of losing power and hope for power, whereas woman without AN had significantly lower fear of losing power than hope for power. Focusing on discrepancies between powerful feelings and power motives, results were mixed, depending on the subscale of the MMG. Lastly, discrepancies between implicit power motives and explicit feelings of power were positively correlated with trait anxiety in AN patients.ConclusionThese findings underline that individuals with AN display significantly lower explicit feelings of power, however, they show similar implicit power motives compared to individuals without AN. The discrepancy between explicit feelings of power and implicit power motives is related to anxiety in AN and may represent a vulnerability factor to illness maintenance. (shrink)

K. Lüscher, A. Klimczuk, Generations, intergenerational relationships, generational policy: A multilingual compendium, 17 languages, Universität Konstanz, Konstanz 2017, 428pp. TS - BibTeX M4 - Citavi.

K. Lüscher, A. Klimczuk, Generations, intergenerational relationships, generational policy: A multilingual compendium, 17 languages, Universität Konstanz, Konstanz 2017, 428pp. TS - BibTeX M4 - Citavi.

K. Lüscher, A. Klimczuk, Generations, intergenerational relationships, generational policy: A multilingual compendium, 17 languages, Universität Konstanz, Konstanz 2017, 428pp. TS - BibTeX M4 - Citavi.

En este artículo se parte de la crítica de Feuerbach a la religión para recuperar el sentido humanista de dicha crítica, que más que una afirmación del ateísmo o una negación de la existencia de Dios es una defensa de la dignidad y de la libertad humana. A lo largo de este estudio se sitúa el pensamiento de Feuerbach más allá de la discusión entre el teísmo y el ateísmo, estableciendo un diálogo que deja a un lado las limitaciones de (...) esta dicotomía. En la Historia de la filosofía se ha insistido en la importancia del pensamiento de Feuerbach para la posterior filosofía de la sospecha, pero en este caso se recorre una vía menos explorada: su relación con el pensamiento dialógico y la religión del amor. (shrink)

In the midst of the global financial crisis and in the ‘anti-race era’, Europe has witnessed a revival of deeply racialized discourses targeting the Roma, leading to new discriminatory practices and legitimating existing ones in many social domains. While westward Roma immigration has spurred these discourses, it has also favored the emergence of invisible grassroots reactions against them that need to be further analyzed. Drawing on interviews with migrant Romani women, this article aims to shed light on these unknown processes, (...) as experienced by women in Romani women-based solidarity networks. Data show that these networks help the women to access basic social facilities, while also challenging the abovementioned racialized discourses. (shrink)

In this paper, we explore the concept of bearing witness in nursing practice. We examine the description of bearing witness in the nursing literature, particularly that offered by William Cody who suggests that bearing witness results in the limited moral obligation of “true presence.” We then turn to Lorraine Code's work on testimony, drawing parallels between the concepts of testimony and bearing witness. Code suggests that receiving testimony results in a responsibility to respond, and that this is an ethico‐political obligation. (...) We discuss these ideas in relation to a Canadian exemplar of witnessing the Truth and Reconciliation Commission of Canada's work to understand and address the historical injustices done to Indigenous peoples in Canada. Here, we focus on the Commission's definition of witnessing and highlight the experience of Shelagh Rogers who served as an honorary witness. As an outcome of our analysis, we suggest that bearing witness in nursing practice is most usefully conceptualized as both a moral and a political obligation. Implications for nursing practice are suggested, including first, the need to critically examine our own understandings of power and privilege in order to authentically bear witness and avoid being complicit in injustice, and second, the concomitant responsibility to take action to challenge injustice once we have borne witness to it. (shrink)

The article is devoted to innovative postmodern requests for the liberalization of education. Postmodernism influenced education not only methodologically, but also by changing the very pedagogical culture of teaching. Now the relevance of the research topic is due to the problems of forming information content and methodological support for the introduction of distance learning technology in mobile form. The introduction of IT in education, the improvement of smart devices, the formation of an electronic information and educational environment have created the (...) basis for such forms of education as mobile learning and blended learning. In both cases, the student situationally himself forms the educational process, turns from an object of training into its subject. The humanistic potential of mobile learning in the sense of ensuring equal access to education for people with different abilities is noted. The opinion is expressed about the importance of student motivation and IT competence of teachers to provide information content, intensify the introduction of e-learning and mobile-oriented learning technologies. It is argued that learning based only on mobile learning technology, using smart devices without classroom or office work, real communication with the teacher is not didactically self-sufficient, which would provide adequate language skills. Effectiveness in learning foreign languages is achieved by synergy of technologies distance mobile and traditional classroom or classroom training, real communication with the teacher. (shrink)

Background: Obstetric labor and childbirth are mostly regarded as a physiological process, whereas social, cultural, psychological and transcendental aspects have received less attention. Labor support has been suggested to promote labor progress. The aim of this study was to investigate whether continuous labor support by a midwife promotes labor progress and vaginal delivery.Material and Methods: A randomized controlled study at a university hospital in Sweden in 2015–17. Primiparous women with singleton pregnancy and spontaneous labor onset were randomized to continuous support (...) or standard care during delivery. The primary outcome was the duration of active labor. Secondary outcomes were delivery mode, women's need of labor analgesia and satisfaction with delivery, maternal cortisol levels, and neonatal morbidity.Results: Continuous support was followed by shorter active labor 11.0 ± 5.7 h compared to 13.7 ± 3.9 h with standard care. Women in the continuous support group tended to have lower cortisol levels and low cortisol during the first and second stages of labor were correlated with shorter active labor. Continuous support was followed by spontaneous delivery in 73%, instrumental delivery in 24% and emergency cesarean section in 3% in contrast to standard care which was followed by spontaneous delivery in 62%, instrumental delivery in 24% and cesarean in 14%. The continuous support group received combined analgesic methods more often. Women's satisfaction with delivery and neonatal morbidity were comparable.Conclusion: Continuous labor support was followed by shorter active labor compared to standard care. Women with continuous support had a high rate of vaginal delivery and tended to have lower cortisol levels during all stages of active labor reflecting a lower stress level. Low cortisol was correlated to shorter active labor. Based on these results, we recommend continuous labor support for all primiparous women during active labor. (shrink)

O artigo apresenta uma visão panorâmica dos documentos da Conferência dos Bispos latino-americanos, realizada em Medellín, no ano de 1968. Inicialmente, distingue o Medellín histórico do Medellín simbólico. A seguir, recorda como Assembleia foi bem preparada e se realizou de forma participativa. Então, demonstra a relação de continuidade com o Vaticano II. De outro lado, Medellín não foi uma mera aplicação do Concílio, mas sim uma recepção criativa. No núcleo do artigo, demonstra-se como o método VER-JULGAR-AGIR foi utilizado nos vários (...) documentos de Medellín, alocados em três eixos: promoção humana, evangelização e crescimento da fé, Igreja visível e suas estruturas. Por fim, ele se detém em dois documentos: Pobreza na Igreja e Liturgia. Encerra-se com algumas conclusões abertas, de caráter pastoral. (shrink)

Dans le champ de la linguistique francaise, Olga Galatanu est de ceux qui ont muni l'analyse du discours et des interactions verbales d'un modele semantique de description. La Semantique des Possibles Argumentatifs qu'elle developpe depuis une vingtaine d'annees adhere aux visions argumentative, stereotypique, referentielle, cognitiviste de la langue, et s'attache a rendre compte de la construction des representations en langue et en discours.<BR> Les articles que ses collaborateurs et amis lui offrent dans ce volume se rapportent de pres ou (...) de loin a la SPA. Certains en partagent les postulats: sens referentiel et denomination, interfaces semantique-syntaxe et semantique-pragmatique, construction discursive du sens, valeurs; d'autres reprennent et developpent des elements specifiques de la SPA: possibles argumentatifs, deploiements argumentatifs, modalites; d'autres encore montrent les convergences et complementarites entre la SPA et des theories voisines.<BR> Les analyses portent notamment sur l'attitude metalinguistique des locuteurs, la malleabilite semantique des mots, la negociation des sens et des valeurs, les principes et strategies discursives qui regulent la communication, l'heterogeneite discursive, la presentation de soi, la construction d'objets discursifs, les actes de langage indirects, etc.". (shrink)

Confronted with an unprecedented scale of human-induced environmental crisis, there is a need for new modes of theorizing that would abandon human exceptionalism and anthropocentrism and instead focus on developing environmentally ethical projects suitable for our times. In this paper, we offer an anti-anthropocentric project of an ethos for living in the Anthropocene. We develop it through revisiting the notion of sustainability in order to problematize the linear vision of human-centric futurity and the uniform ‘we’ of humanity upon which it (...) relies. We ground our analyses in posthumanism and material feminism, using works by posthumanist and material feminist thinkers such as Stacy Alaimo, Rosi Braidotti, Donna Haraway and Jane Bennett, among others. In dialogue with them, we offer the concept of posthuman sustainability that decenters the human, re-positions it in its ecosystem and, while remaining attentive to difference, fosters the thriving of all instances of life. (shrink)

Este estudo investiga como o contexto histórico e social da pandemia de COVID-19 pode desencadear o processo criativo, com foco na arte como meio de expressão e reflexão sobre a vacina. Utilizando a Gestalt-terapia como referencial teórico, explora-se o processo criativo de um artista que usa o desenho como uma linguagem capaz de despertar o humor, a reflexão, e de construir sentidos de identificação, consciência em relação a um tema cotidiano. A pesquisa usa o método de análise de conteúdo da (...) entrevista e dos desenhos criados por Humberto Soares na série "Seres Vacinados", analisando-a através de conceitos da Gestalt-terapia como figura e fundo, contato, awareness e campo/organismo/ambiente série. O estudo destaca o quanto a práxis criativa combina a capacidade de imaginar possibilidades novas e inovadoras com a habilidade de traduzir essas ideias em ações tangíveis e impactantes durante tempos de pandemia. (shrink)

This book analyzes unobvious relations between historical definitions of the face and its contemporary usage in popular culture and social media, like Facebook or Instagram. Bringing together a wide range of methodologies, it includes essays from manifold disciplines of the humanities such as philosophy, literary and art criticism, media and television studies, game studies, sociology and anthropology. The authors focus on both metaphorical and material meanings of the face. They grapple with crucial questions about modernity, modern and postmodern subjectivity, as (...) well as with origins of certain linguistic terms and popular, colloquial phrases based on the concept of the face. (shrink)

Neste trabalho, nosso objetivo foi expor a relevância das bases teórico-metodológicas da história da educação do tempo presente e desta para a pesquisa histórico-educacional. Partimos dos alicerces da história do tempo presente, destacando alguns conceitos construtores desse campo oriundos de autores como Rémond, Bédarida e Chartier, entre outros. A seguir, trabalhamos os avanços e os desafios enfrentados pelos pesquisadores desse campo. As fontes disponíveis para as pesquisa da história da educação do tempo presente foram destacadas, argumentando que a abundância delas (...) e a proximidade do pesquisador em relação ao tempo da sua ação não facilitam a pesquisa e não diminuem sua necessária rigorosidade. Os alicerces da história do tempo presente, os desafios, os avanços, suas fontes abundantes e sua aplicação rigorosa constroem uma nova epistemologia para a história da educação, marcada pelas incertezas que referenciam a centralidade da problematização na pesquisa histórica. Toda essa argumentação é reforçada pela idéia originária de que a educação, como uma prática social, exige de seus pesquisadores a consecução dos depoimentos orais, das informações e de todos os tipos de documentação oriundas dos sujeitos que a fizeram/fazem. Dans ce travail, nous avons eu pour objectif de montrer et de défendre l’importance de l’histoire de l’éducation du temps présent pour la recherche historico-éducative. Nous avons pris comme point de départ les fondements de l’histoire du temps présent, en soulignant quelques concepts constructeurs de ce champ créés par des auteurs tels que Rémond, Bédarida et Chartier, entre autres. Ensuite, nous avons analysé les avancements et les enjeux affrontés par les chercheurs de ce domaine. Les sources disponibles pour les recherches sur l’histoire de l’éducation du temps présent ont été mises en relief, en considérant le fait que leur abondance et la proximité du chercheur par rapport au moment de son action ne facilitent pas son travail ni en diminuent la rigueur nécessaire. Les fondements de l’histoire du temps présent, les enjeux, les avancements, ses sources abondantes et son application rigoureuse construisent une nouvelle épistémologie pour l’histoire de l’éducation marquée par les incertitudes qui fondent la centralité de la problématisation dans la recherche historique. Toute cette argumentation est renforcée par l’idée originaire selon laquelle l’éducation, en tant que pratique sociale, exige de ses chercheurs la consécution des témoignages oraux, des informations ainsi que de toute sorte de documents provenant des sujets qui l’ont faite/la font. (shrink)

Several studies have illuminated how processing manual action verbs (MaVs) affects the programming or execution of concurrent hand movements. Here, to circumvent key confounds in extant designs, we conducted the first assessment of motor–language integration during handwriting—a task in which linguistic and motoric processes are co‐substantiated. Participants copied MaVs, non‐manual action verbs, and non‐action verbs as we collected measures of motor programming and motor execution. Programming latencies were similar across conditions, but execution was faster for MaVs than for the other (...) categories, regardless of whether word meanings were accessed implicitly or explicitly. In line with the Hand‐Action‐Network Dynamic Language Embodiment (HANDLE) model, such findings suggest that effector‐congruent verbs can prime manual movements even during highly automatized tasks in which motoric and verbal processes are naturally intertwined. Our paradigm opens new avenues for fine‐grained explorations of embodied language processes. (shrink)

Since the beginning of signed language research, the linguistic units have been divided into conventional, standard and fixed signs, all of which were considered as the core of the language, and iconic and productive signs, put at the edge of language. In the present paper, we will review different models proposed by signed language researchers over the years to describe the signed lexicon, showing how to overcome the hierarchical division between standard and productive lexicon. Drawing from the semiotic insights of (...) Peirce we proposed to look at signs as a triadic construction built on symbolic, iconic, and indexical features. In our model, the different iconic, symbolic, and indexical features of signs are seen as the three sides of the same triangle, detectable in the single linguistic sign. The key aspect is that the dominance of the feature will determine the different use of the linguistic unit, as we will show with examples from different discourse types. (shrink)

This article examines the discourse competence of high-functioning children with autistic spectrum disorders to participate in narrative introduction sequences with family members. The analysis illuminates the children’s own efforts to launch narratives, as well as their ability to build upon the contributions of others. Ethnographic, discourse analytic methodology is integrated with the theory of discourse organization and the weak central coherence account of autism. Introductions of both personal experience narratives as well as fictional narratives are examined. The children were especially (...) competent in the use of stable introductory practices when launching fictional narratives, pre-organized by the media of expression. Their challenge was not in the introduction, but in the narrative co-telling, which often was not globally organized over an extended course of propositions. The heterogeneity of the ASD children’s discourse competence and its implications for discourse analysis are discussed. (shrink)

Expressions of nationalisms, identity-based conflicts and violent (de)territorializations are increasingly frequent and widespread throughout the world, related very often to the dynamics of human mobilities and geopolitical reconfigurations. They embody a complexity which, in this article, will serve a theoretical critique of the present and the equation of transformations in the processes of production of social relations, structures of social living and subjectivity. Contemporary socio-political conflicts are thus aligned with questions about the possibility of collective endeavours and its conditions of (...) applicability - in contexts of dispersion, conflict, and inequality - as preventive or mitigatory efforts for potential disasters. (shrink)

This paper deals with Bonaventure’s stand on the separability of accidents discussed within the framework of the theology of the Eucharist, in his Commentarium in Sententias, IV, d. 12, p. 1, a. 1, q. 1. Since an accident was traditionally defined as ens in alio, the existence of accidents apart from any subject in the Eucharist was considered philosophically challenging. The Franciscan theologian has been credited with having distinguished, for the first time (Bakker PJJM. La raison et le miracle: les (...) doctrines eucharistiques (c. 1250 – c.1400): contribution à l’étude des rapports entre philosophie et théologie. s.n., Nijmegen, 1999; Vijgen J. The status of Eucharistic accidents “sine subiecto”: An historical survey up to Thomas Aquinas and selected reactions. München: Akademie Verlag, 2013), between the relation of accident to subject secundum aptitudinem, and the relation of accident to subject secundum actum, while sustaining that only the relation to subject secundum aptitudinem constitutes the accident’s proper definition, a view that Aquinas would subscribe to and develop further, relying on Avicenna’s idea of the real distinction between essence and existence. The chapter will discuss Bonaventure’s rather different reasons for refusing to accept actual being in alio as the accident’s essence. Bonaventure does not appeal to a distinction between being and essence but draws on the common essence of accidents in individualized substances vs. accidents as universals, or accidents secundum species sive differentias speciales. (shrink)

A não-violência não se reduz a uma posição moral individualista. Como luta coletiva contra a violência sistémica ou instituída configura uma forma efetiva de agência e de poder político com um compromisso ético global pela igualdade. Sob esta perspetiva, a sua análise proporciona outros entendimentos de indivíduo, da igualdade e dos fundamentos dos laços sociais, noções que se redesenham no âmbito de um mundo social cada vez mais interdependente.

This work seeks to understand the dominant socio-political view of Church authority in the context of history, and to articulate a vision of non-political authority in the Church drawn from spiritual anthropology rather than from political theories.

At the bedside, nurses are expected to be precise when they read indications on screens and on the bodies of patients and decide on the meaning of words framed by the context of acute care. In academia, although there is no incident report to fill when we misread or misrepresent complex philosophical ideas, the consequences of inaccurate reading include misplaced epistemological claims and poor scholarship. A long and broad convention of nursing phenomenological research, in its various forms, claims a philosophical (...) grounding in the ideas of Husserl, Heidegger, and other thinkers. But for nearly two decades, nurse phenomenologists' knowledge claims have been challenged by well‐informed criticisms, most notably by John Paley. At the heart of criticism lies an observation that Continental phenomenological thought is misrepresented in many nursing sources and that nursing phenomenology, both descriptive and interpretive, cannot appeal to the authority of either Husserl or Heidegger. Taking these criticisms seriously, I am asking, Is phenomenology after Paley possible? If misreading seems to be an issue, how can – or should – we read rigorously? My thinking through these questions is influenced by the ideas of Jacques Derrida. Under a condition of a play of language, of Derridian différance, when meaning is never self‐identical and never fully arrives, I suggest that one has to negotiate meanings through reading for differences. I develop this idea in relation to the methodological conventions of phenomenological nursing research and argue for a careful rereading of the whole field of phenomenological nursing research. Such rereading presupposes and necessitates interdisciplinary engagement between nursing and the humanities and interpretive social sciences. Greater familiarity with research practices of those disciplines that stress theoretical and writing rigour might make visible the limits of nursing research approaches and their quality criteria. An understanding of philosophical and theoretical works – a condition of quality scholarship – depends on our reading of both originary texts and contemporary literature from the humanities and the social sciences. This understanding, far from obliging researchers to always trace (often erroneously) their work to its philosophical roots, opens other, often more sound, methodological possibilities. (shrink)

In common law jurisdictions, legal professionals cite facts and legal principles from precedent cases to support their arguments before the court for their intended outcome in a current case. This practice stems from the doctrine of stare decisis, where cases that have similar facts should receive similar decisions with respect to the principles. It is essential for legal professionals to identify such facts and principles in precedent cases, though this is a highly time intensive task. In this paper, we present (...) studies that demonstrate that human annotators can achieve reasonable agreement on which sentences in legal judgements contain cited facts and principles. We further demonstrate that it is feasible to automatically annotate sentences containing such legal facts and principles in a supervised machine learning framework based on linguistic features, reporting per category precision and recall figures of between 0.79 and 0.89 for classifying sentences in legal judgements as cited facts, principles or neither using a Bayesian classifier, with an overall κ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\kappa$$\end{document} of 0.72 with the human-annotated gold standard. (shrink)