Spermiogenesis is an important physiological process of mammalian fertilization. The germ cells are susceptible to the harmful effects of either psychological or physiological stress, which could induce male infertility. Our previous studies have found that chronic psychological stress could decrease sexual motivation. However, molecular mechanisms underlying male reproductive toxicity induced by chronic stress remain elusive. Recently, autophagy is proven to be involved in regulating the survival of germ cells, which is related to apoptosis. Herein, we established a chronic psychological stress (...) model and a chronic pain model (physiological stressor) to explore the roles of autophagy in germ cells. Thirty-two male Sprague-Dawley rats were randomly divided into four groups, including the control group, the chronic psychological stress group, the SNI-sham group, and the chronic pain stress group. After exposure to stress for 35 days, open field test and the unconditioned sexual motivation test were performed. Following the behavioral experiment, autophagy in the rat testis was detected by Western blot and immunohistochemistry. We found both chronic psychological stress and chronic pain stress reduced total travel distance, the frequency of central crossing and increased the sensitivity to mechanical pain. While chronic psychological stress, but not the chronic pain stress declined sexual motivation. Chronic psychological stress prompt the expression of LC3-II with the decreased expression of p62, indicating that chronic psychological stress induced autophagy in rat testis. However, there was no significant difference between the expression of LC3-II and p62 in male rats under chronic pain stress. Therefore, chronic psychological stress and chronic pain stress have common behavior changes, but due to its unpredictability, chronic psychological stress leads to a decline in sexual motivation in male rats and induced the autophagy in testicular tissues. (shrink)

Shang ce. Ru xue yu si xiang -- xia ce. Qing dai xue shu si chao.

法律文化,是各民族、各国家和各地区法律善的整体表现,涉及法制建设和法律发展的整体水平,如立法、执法、司法和守法,以及法律教育、法律职业,民众的法律意识和法律观念等的发展状态。.

本书收集的文章包括“人与社会的全面发展是和谐社会的本质”、“和谐社会的义利观”、“论人的物性与人的人性”、“坚持‘领导就是服务’的执政价值观”等。.

本书收录何兆武先生的读书心得,通过回忆与师友一起读书,交流,工作的岁月,从一个侧面回顾了20世纪上半叶中国历史上一代学者的思想成就,桥接了新旧两个时代的思想与历史,触摸到一个历史时代的灵魂.

Contemporary scholarships on various accounts of the concept of harmony in Chinese philosophy have produced fruitful outcomes by examining the term he. A standard use of he to account for harmony comes from the Analects, and this account sets up disjunctions not just between he and tong but also between harmony and tong. Such disjunctions are even more conspicuous in the political discourses from the Zuozhuan and Guoyu, and hence, has led scholars to overlook the more nuanced resonances between tong, (...) he, and harmony that can be identified from other canonical texts, such as in shangtong of the Mozi, in hetong of the Guanzi, and in datong of the Liji. This article aims to present nuanced relations between harmony, he, and tong, and proposes tong as another viable option to express harmony, thereby correcting the imbalance that the predominant scholarships recognize he and neglect tong. (shrink)

何定生是顧頡剛在廣州中山大學任教時的學生，早年即已有文章收錄於《古史辨》中，而享有古史辨學者的光環。一九四九年隨國民政府來臺，任教於臺大中文系。生前出版有《詩經今論》一書，收錄三篇《詩經》研究論文，為 臺灣學界所仰重。一九七○去世後，其弟子何寄澎、曾志雄整理遺稿，出版《定生論學集──詩經與孔學研究》，收錄四篇論著。《何定生著作集》即在此二書的基礎上，復廣泛蒐求其論著、書信與相關資料，編為二冊。第一冊 為《何定生著作集一：詩經、孔學及其他》，第二冊為《何定生著作集二：尚書與文法》，雖尚未能將何氏著作網羅殆盡，但已足將何氏學術的主要面向及研究精華充分展現出來。 何定生深受五四以來新文化運動的影響，繼承顧頡剛及古史辨的學風，將此學風在戰後的臺灣學界持續發皇。何定生的學問主要表現在《詩經》，強調復古解放的精神，他呼籲今日的《詩經》研究，應從清學的漢學壁壘中出來， 以復於原始的樂歌地位。他認為惟有站在《儀禮》的樂歌地位來讀《詩經》，從人性的同類意識來接觸人性，才有碰到詩人靈感的可能。.

Contemporary scholarships on various accounts of the concept of harmony in Chinese philosophy have produced fruitful outcomes by examining the term he. A standard use of he to account for harmony comes from the Analects, and this account sets up disjunctions not just between he and tong but also between harmony and tong. Such disjunctions are even more conspicuous in the political discourses from the Zuozhuan and Guoyu, and hence, has led scholars to overlook the more nuanced resonances between tong, (...) he, and harmony that can be identified from other canonical texts, such as in shangtong of the Mozi, in hetong of the Guanzi, and in datong of the Liji. This article aims to present nuanced relations between harmony, he, and tong, and proposes tong as another viable option to express harmony, thereby correcting the imbalance that the predominant scholarships recognize he and neglect tong. (shrink)

本书收录的16篇文章分为两个部分:第一部分属于哲学伦理学部分,包括政治哲学、应用伦理,也涉及到宗教与形而上学;第二部分是社会史部分,解释近三千年中国社会历史方面的初步探讨。.

Evidence suggests that English speakers use pronouns when referring to the grammatical subject and predictable thematic role. We tested how grammatical role and thematic role predictability affect different types of referential forms, namely, overt pronouns and null pronouns in Mandarin Chinese. We found that both overt and null pronouns were sensitive to grammatical role. However, we did not find any evidence that overt and null pronouns were sensitive to thematic role predictability. Although null pronouns were influenced by grammatical role, the (...) rate of null pronouns for subject reference was very low compared to that of overt pronouns. Given the frequent occurrence of null pronouns in Mandarin, our results suggest that the use of null pronouns may not be explained by a simple grammatical role mechanism. (shrink)

Background: There is controversy concerning the use of physical restraint. Despite this controversy, some nurses still consider the application of physical restraint unavoidable for some of their clients. Aim: Identify the perceptions and practice of physical restraint in China. Research design: This was a descriptive study that combined qualitative interviews with a quantitative cross-sectional survey. Participants: A total of 18 nurses were interviewed and 330 nurses were surveyed. Ethical considerations: Approval of the study was obtained from the hospital ethics committee. (...) Permission to conduct the study was obtained from the director of nursing. Participants were assured that their participation is voluntary. Results: Physical restraint was commonly used to protect patients’ safety. Naturally, intensive care unit nurses used physical restraint much more frequently than general medical/surgical ward nurses ( p < 0.01). In addition, night shift nurses tended to use physical restraint more frequently. Conclusion: Nursing managers should be aware of the role nurses play in the use of physical restraint. In-service training regarding the proper use of physical restraint should be strengthened and nurse staffing levels should be improved in order to minimize the use of physical restraint in China. (shrink)

This paper introduces the Generalized Argumentation Theory which takes argumentation as a locally rational socio-cultural interaction governed by social norms and carried out through discourse between the members of a socio-cultural community in order to reason things out. Then we bring in the basic structure of generalized argumentation and the localized procedure of Generalized Argumentation Theory for studying the argumentative rules. On the basis of above introduction, we use the localized procedure to analyze a case of political argumentation by reciting (...) poems in ancient China. By doing so, it’s indicated that political argumentation by reciting poems, in essence, takes cultural principle of Li of the Spring and Autumn Period as argumentative rules and uses poems to express ideas, in virtue of which arguments are accepted as locally rational by the politicians at that time. At last, the Little Red Book quotation fight, a similar political activity, is discussed briefly to show the significance that ancient Chinese political argumentation has on contemporary argumentation. (shrink)

本书包括:在京西宾馆的报告;我读懂了马克思,因而反对伪科学;经验不等于实践;我的科学观与人文观等内容。.

In this article, the author aims to demonstrate how Agamben’s concept of Homo Sacer is ideally epitomized by a soldier in war. A soldier in war holds a peculiar position, as killing of soldiers is considered neither illegal by laws nor immoral by ethics, and so a soldier is not considered to be legally or morally “guilty” in the usual sense of the word if he or she kills another soldier in war. The author analyzes the notion of Homo Sacer (...) – a figure representing a human that can be killed without the killer being punished, but at the same time someone who cannot be sacrificed – and further demonstrates that a soldier in war can be said to hold precisely such a status. The reason why a soldier cannot be sacrificed resides in the fact that he has already been “sacrificed to war” by his own society, in exchange for the safety of all other members of society. Perceiving a soldier as Homo Sacer provides a novel explanation and an additional argument for the moral symmetry of combatants, one of the pillars of non-revisionist Just War Theory, as all soldiers can be understood as persons sacrificed by their own societies. (shrink)

China now faces a national identity problem, that is, sections of the national population do not identify with the Chinese nation-state in which they live. Tibetans, for example, endeavor to create their own political identity through the reconstruction of a Tibetan cultural and ethnic identity. China's national identity problem also involves the question of reunification with Taiwan. In Taiwan, both the Guomindang and the Democratic Progressive Party governments have refused to reunify with China. The question of Taiwan and Tibet are (...) different cases and require different treatment,1 but Beijing's response to the two questions—refusing to adopt a democratic approach—is the same. (shrink)

Kant’s Dreams of a Spirit Seer has puzzled most of its readers since its publication in 1766. Herder complained in general terms about the lack of unity and coherence of the book as well as Kant’s dialectical method of presenting both sides of a problem without offering his own solution. Mendelssohn was in doubt about whether Kant wanted to ridicule metaphysics or make a case for Swedenborg’s visions. Another exegetical puzzle has not been noted yet: Dreams discusses not one, but (...) three different versions of a ‘metaphysics of spirits’. All of them are mutually incompatible. In other words, the two versions of a metaphysics of spirits that Kant criticises in the first part of the book are both of them different from Swedenborg’s own claims, as they are discussed in the second part. And the two versions discussed within the first part are not homogeneous, either: the metaphysics discussed in the first chapter of the first part (the ‘tangled knot’) and those that seem to form the foundation for the second chapter of the first part (the ‘fragment of occult philosophy’) are again incompatible. And neither of them fits with what Kant analyses as Swedenborg’s metaphysical position in the second part: The position of the ‘tangled knot’ can tentatively be labelled as ‘crypto-materialist’. Swedenborg’s own position is characterised in the text as ‘idealist’. The ‘fragment of occult philosophy’ in contrast is probably best described as ‘dualist’. If this diagnosis is correct, it reinforces Herder’s complaints about the lack of coherence of Dreams as well as Mendelssohn’s worry about its targets. And it adds the additional challenge to explain how there can be a ‘crypto-materialist’ metaphysics of spirit-seeing. I propose to weaken the impact of these problems by identifying a second target of Kant’s scorn in Dreams – a metaphysical position Kant could be sympathetic with as far as its fundamental intentions are concerned, but that draws his ire because of an equally comprehensive failure in the realisation of these intentions. (shrink)

Drawing on his extensive experience as both a medical practitioner and a patient, acclaimed author, award-winning physician, and ethicist Philip Hébert creates a brave and intimate portrait of the complex ethical questions raised by revolutionary advances in medical diagnosis and treatment. Philip Hébert addresses the complex ethical questions raised by revolutionary advances in medical treatment. This work expands upon Hébert's previous book, "Doing Right," and extends his knowledge of the field beyond medical professionals to reach the patients they treat.