The pessimistic induction over scientific theories holds that present theories will be overthrown as were past theories. The pessimistic induction over scientists holds that present scientists cannot conceive of future theories just as past scientists could not conceive of present theories. The pessimistic induction over realists :4321–4330, 2013) holds that present realists are wrong about present theories just as past realists were wrong about past theories. The pessimistic induction over antirealist theories :3–21, 2014) holds that the latest antirealist explanation of (...) the success of science :891–901, 2003) has hidden problems just as its eight predecessors did. In this paper, I criticize the pessimistic inductions over scientific theories, scientists, and realists, introduce a pessimistic induction over antirealist theories, and then construct two new pessimistic inductions. One is a pessimistic induction over antirealists according to which the author of the latest antirealist proposal cannot see hidden problems with his proposal just as his antirealist predecessors could not see hidden problems with their proposals. The other is the pessimistic induction over pessimists according to which since past pessimists have been wrong about their present scientific theories from the early twentieth century to the early twenty-first century, future pessimists will also be wrong about their present scientific theories from the early twenty-first century to the early twenty-second century. (shrink)

Autophagy and YAP1‐WWTR1/TAZ signalling are tightly linked in a complex control system of forward and feedback pathways which determine different cellular outcomes in differing cell types at different time‐points after perturbations. Here we extend our previous experimental and modelling approaches to consider two possibilities. First, we have performed additional mathematical modelling to explore how the autophagy‐YAP1 crosstalk may be controlled by posttranslational modifications of components of the pathways. Second, since analogous contrasting results have also been reported for autophagy as a (...) regulator of other transduction pathways engaged in tumorigenesis (Wnt/β‐catenin, TGF‐β/Smads, NF‐kB or XIAP/cIAPs), we have considered if such discrepancies may be explicable through situations involving competing pathways and feedback loops in different cell types, analogous to the autophagy‐YAP/TAZ situation. Since distinct posttranslational modifications dominate those pathways in distinct cells, these need to be understood to enable appropriate cell type‐specific therapeutic strategies for cancers and other diseases. (shrink)

After decades of intense debate over the old pessimistic induction (Laudan, 1977; Putnam, 1978), it has now become clear that it has at least the following four problems. First, it overlooks the fact that present theories are more successful than past theories. Second, it commits the fallacy of biased statistics. Third, it erroneously groups together past theories from different fields of science. Four, it misses the fact that some theoretical components of past theories were preserved. I argue that these four (...) problems entitle us to construct what I call the grand pessimistic induction that since the old pessimistic induction has infinitely many hidden problems, the new pessimistic induction (Stanford, 2006) also has infinitely many hidden problems. (shrink)

In a recent Target Article Naomi Scheinerman (2023a) has offered an important and compelling call to institutionalize popular participation for heritable genome engineering through the inclusion of...

The pessimistic induction is built upon the uniformity principle that the future resembles the past. In daily scientific activities, however, scientists sometimes rely on what I call the disuniformity principle that the future differs from the past. They do not give up their research projects despite the repeated failures. They believe that they will succeed although they failed repeatedly, and as a result they achieve what they intended to achieve. Given that the disuniformity principle is useful in certain cases in (...) science, we might reasonably use it to infer that present theories are true unlike past theories. Hence, pessimists have the burden to show that our prediction about the fate of present theories is more likely to be true if we use the uniformity principle than if we use the disuniformity principle. (shrink)

This paper investigates the transformative influence of generative AI on the arts, connecting it with Walter Benjamin's insights regarding the aura of art in the mechanical reproduction era. It scrutinizes how generative AI not only redefines art's traditional aura but also introduces a dynamic interplay between technological liberation and dependency. The analysis extends to the democratization of artistic expression and its broader societal impacts, highlighting a shift in art creation, perception, and interpretation in the digital age. This research encapsulates the (...) evolving nature of authenticity, creativity, and human–machine collaboration, marking a significant paradigm shift in art's conception and its role in society. (shrink)

Dellsén (2016a) argues that understanding requires neither justification nor belief. I object that ridding understanding of justification and belief comes with the following costs. (i) No claim about the world can be inferred from what we understand. (ii) We run into either Moore’s paradox or certain disconcerting questions. (iii) Understanding does not represent the world. (iv) Understanding cannot take the central place in epistemology. (v) Understanding cannot be invoked to give an account of scientific progress. (vi) It is not clear (...) how misunderstanding arises. (shrink)

The current study presents the findings of an empirical inquiry into the effects of Confucian ethics and collectivism, on individual whistleblowing intentions. Confucian Ethics and Individualism–Collectivism were measured in a questionnaire completed by 343 public officials in South Korea. This study found that Confucian ethics had significant but mixed effects on whistleblowing intentions. The affection between father and son had a negative effect on internal and external whistleblowing intentions, while the distinction between the roles of husband and wife had a (...) positive effect on those intentions. The effects of collectivism were also different depending on the specific types of collectivism. Horizontal collectivism had a positive effect on both types of whistleblowing intentions, whereas vertical collectivism did not show any significant effects on whistleblowing intentions. These results indicate that cultural traits such as Confucian ethics and collectivism may affect an individual’s whistleblowing intentions in degree and direction, making blanket predictions about cultural effects on whistleblowing difficult. (shrink)

This study focuses on CEO hubris and its detrimental effect on corporate financial performance along with an examination of critical corporate governance contingencies that may moderate the negative effect. From 654 observations of 164 Korean firms over the years 2001–2008, we found that CEO power exacerbated the negative effect of CEO hubris on corporate financial performance, whereas board vigilance mitigated it. This study provides empirical evidence that entrenchment problems arising from CEO hubris would be exacerbated as CEOs become more powerful, (...) but weakened as board of directors become more vigilant. Theoretical contributions and practical implications will be discussed. (shrink)

Business Ethics: A European Review, EarlyView.

This Korean study replicated a previously published American study. The conceptual framework and method combined ethical enquiry and phenomenology. The research questions were: (1) What is nursing students’ experience of ethical problems involving nursing practice? and, (2) What is nursing students’ experience of using an ethical decision-making model? The participants were 97 senior baccalaureate nursing students, each of whom described one ethical problem and chose to use one of five ethical decision-making models. From 97 ethical problems, five content categories emerged, (...) the largest being health professionals (69%). The basic nature of the ethical problems was the students’ experience of conflict, resolution and rationale. Using an ethical decision-making model helped 94% of the students. A comparison of the Korean and American results yields important implications for nursing ethics education, practice and research. (shrink)

Pessimists predict that future scientific theories will replace present scientific theories. However, they do not specify when the predicted events will take place, so we do not have the chance to blame them for having made a false prediction, although we might have the chance to praise them for having made a true prediction. Their predictions contrast with astronomers’ predictions. Astronomers specify when the next solar eclipse will happen, so we have both the chance to blame them for having made (...) a false prediction and the chance to praise them for having made a true prediction. The pessimists’ prediction remains unvirtuous until they specify when scientific revolutions will occur. This critical point applies no less to the selectivist’s prediction. (shrink)

Hempel, Popper, and Kuhn argue that to be scientific is to be testable, to be falsifiable, and most nearly to do normal science, respectively. I argue that to be scientific is largely to be interactive, offering some examples from science to show that the ideas from different fields of science interact with one another. The results of the interactions are that hypotheses become more plausible, new phenomena are explained and predicted, we understand phenomena from a new perspective, and our worldview (...) becomes simpler. I also argue that given that the interactions are impressive features of science, astrology and religion would be regarded as science, provided that there are similar interactions in those enterprises. (shrink)

In light of rampant fake news and disinformation in today's press and social media, I provide a new consequentialist argument that regulations on the media pertaining to certain false verifiable empirical facts are warranted. This contention is based in part on a collection of pre-existing empirical findings that I newly piece together from political science and psychology demonstrating that a post-truth society is likely with current media. My position is then defended from several counters, such as that it violates deontological (...) rights to free speech and to freedom of the press, that free speech leads to the acquisition of truth, and that government regulators can be biased and corrupt. (shrink)

The genre of fable tends to be overlooked in the study of Korean literary history on the ground that the genre seems too archaic to reflect the aesthetic standards established in the modern European novel, in which the focus lies in the realistic representation of the individual or contemporary society. However, the genre was not completely abandoned by modern Korean writers. Few critics have noted the continuing role played by the rich Korean fable tradition, which eventually made the reinvention of (...) the genre in the mass media possible. In particular, it is worth noting that there was the emergence of a new subgenre of fable in the late nineteenth century: that is, fabulous court case fiction, which is quite distinct from the Chinese literary tradition that had underprivileged imaginative narrative texts under the absolute domination of Confucian historiography. The genre of fabulous court case fiction makes us reconsider the plurality of narrative forms and various narrative functions. In this study, I examine how imaginative narrative texts such as fables simultaneously pursue the pleasure of storytelling and the purposes of both moral and specialized education. (shrink)

In 1965, John A. Pope presented a paper entitled 'Two-Dimensional Chart of Quantum Chemistry' to illustrate the inverse relationship between the sophistication of computational methods and the size of molecules under study. This chart, later called the 'hyperbola of quantum chemistry', succinctly summarized the growing tension between the proponents of two different approaches to computation–the ab initio method and semiempirical method–in the early years of electronic digital computers. Examining the development of quantum chemistry after World War II, I focus on (...) the role of computers in shaping disciplinary identity. The availability of high-speed computers in the early 1950s attracted much attention from quantum chemists, and their community took shape through a series of conferences and personal networking. However, this emerging community soon encountered the problem of communication between groups that differed in the degree of reliance they placed on computers. I show the complexity of interactions between computing technology and a scientific discipline, in terms of both forming and splitting the community of quantum chemistry. (shrink)

Background: The complexity and variety of ethical issues in nursing is always increasing, and those issues lead to special concerns for nurses because they have critical impacts on nursing practice. Research objectives: The purpose of this study was to gather comprehensive information about ethical issues in nursing practice, comparing the issues in different types of nursing units including general units, oncology units, intensive care units, operating rooms, and outpatient departments. Research design: The study used a descriptive research design. Ethics/human rights (...) issues encountered by nurses in their daily nursing practice were identified by using the Ethical Issues Scale. Participants: The study sample included 993 staff nurses working in a university hospital in South Korea. Ethical considerations: This study was approved by the University Institutional Review Board. Completed questionnaires were returned sealed with signed informed consent. Findings: The most frequently and disturbingly encountered issues across nursing units were “conflicts in the nurse–physician relationship,” “providing care with a possible risk to your health,” and “staffing patterns that limit patient access to nursing care.” The findings of this study showed that nurses from different nursing units experienced differences in the types or frequency of ethical issues. In particular, intensive care units had the greatest means of all the units in all three component scales including end-of-life treatment issues, patient care issues, and human rights issues. Discussion: Nurses experienced various ethical challenges in their daily practice. Of the ethical issues, some were distinctively and frequently experienced by nurses in a specific unit. Conclusion: This study suggested that identifying and understanding specific ethical issues faced by nurses in their own areas may be an effective educational approach to motivate nurses and to facilitate nurses’ reflection on their experiences. (shrink)

This study examines the influence of some suspected sources of bias on perceptions of public sector corruption. These sources include dependence on two types of media as information sources about corruption: traditional and social media, positive perception of public employees, and social identification with public employees. Data were collected through a face-to-face survey of the general public in South Korea. The sample comprised 472 respondents evenly dispersed across the country. Through regression analysis, we found that dependence on traditional media—but not (...) social media—significantly increased the perceived level of corruption. However, positive perceptions of and social identification with public employees were negatively associated with it, showing that these factors may skew respondents' perceptions of corruption. The results have implications for practitioners and researchers who design, implement, or evaluate anti-corruption policies, suggesting the need for caution when making use of survey results. (shrink)

The identification of a set of mutually exclusive and exhaustive propositions concerning the states of quantum systems is a corner stone of the information-theoretic foundations of quantum statistics; but the set which is conventionally adopted is in fact incomplete, and is customarily deduced from numerous misconceptions of basic quantum mechanical principles. This paper exposes and corrects these common misstatements. It then identifies a new set of quantum state propositions which is truly exhaustive and mutually exclusive, and which is compatible with (...) the foundations of quantum theory. (shrink)

While there has been much work on cosmological arguments, novel objections will be presented against the modern day rendition of the Kalām cosmological argument as standardly articulated by William Lane Craig. The conclusion is reached that this cosmological argument and several of its variants do not lead us to believe that there is inevitably a supernatural cause to the universe. Moreover, a conditional argument for atheism will be presented in light of the Big Bang Theory.

The evolution of color categorization systems is investigated by simulating categorization games played by a population of artificial agents. The constraints placed on individual agent’s perception and cognition are minimal and involve limited color discriminability and learning through reinforcement. The main dynamic mechanism for population evolution is pragmatic in nature: There is a pragmatic need for communication between agents, and if the results of such communications have positive consequences in their shared world then the agents involved are positively rewarded, whereas (...) if the results have negative consequences, then involved agents are punished. A mechanism for changing the composition of the population due to agents’ birth and death is also investigated. This birth-death mechanism is found to effectively move an established population color naming system toward a theoretically more optimal one. The simulation results of this article provide insights regarding mechanisms that may constrain universal tendencies in human color categorization systems observed in the linguistic and anthropological literatures. (shrink)

Nanay (2017) argues for unconscious mental imagery, inter alia based on the assumption that successful performance in imagery tasks requires the manipulation of mental imagery. I challenge this assumption with the help of results presented in Shepard and Metzler (1971), Zeman et al. (2010), and Keogh and Pearson (2018). The studies suggest that imagery tasks can be successfully performed by means of cognitive/propositional strategies which do not rely on imagery.

In the light of the increased interplay between customers and companies that touches on the diverse aspects (economic, legal, and ethical) of corporate management, it is increasingly important to ask whether customers consider not only the citizenship behaviour of companies but also their own citizenship behaviour as a precursor for ethical consumption. In this respect, this study attempts to answer this question by adopting two of the actors expressing citizenship behaviour, namely customer and company. This study attempts to answer the (...) following three research questions. (1) Do the attitudes of corporate citizenship and customer citizenship correlate with each other? (2) Do two kinds of citizenship attitudes create a positive ethical company attitude? (3) Does an ethical company attitude result in ethical consumption? (shrink)

Merleau-Ponty and Buddhism explores a new mode of philosophizing through a comparative study of Maurice Merleau-Ponty's phenomenology and philosophies of major Buddhist thinkers including Nagarjuna, Chinul, Dogen, Shinran, and Nishida Kitaro. The book offers an intercultural philosophy in which opposites intermingle in a chiasmic relationship, and which brings new understanding regarding the self and the self's relation with others in a globalized and multicultural world.

My 5-year-old granddaughter refers to foods, clothes, and people she does not like as “supergross.” It is a verbiage that I have found myself adopting for talking about many things Trumpian, including the man himself. The gaudy, gold-plated everything in Trump Towers; his ill-fitting suits; his poorly executed fake tan and comb-over; his red baseball cap emblazoned with “Make America Great Again;” his creepy way of talking about women ; his racist vitriol about Blacks, Muslims and Mexicans; his blatant over-the-top (...) narcissism; his uncontrolled tantrums; his ridiculous tweets; his outlandish claims; his awkward hand gestures and handshakes; the disquieting ease with which he is seduced... (shrink)

Numerous supposed immoral mandates and commands by God found in religious texts are introduced and discussed. Such passages are used to construct a logical contradiction contention that is called the moral epistemological argument. It is shown how there is a contradiction in that God is omnibenevolent, God can instruct human beings, and God at times provides us with unethical orders and laws. Given the existence of the contradiction, it is argued that an omnibenevolent God does not exist. Finally, this contention (...) is defended from several objections. (shrink)

This review critically examines the current state of the science on the concept of family caregiver–care receiver mutuality, summarizes accomplishments and gaps and identifies directions for future theory development and research. Mutuality between family caregivers and care receivers is of increasing interest to researchers. However, no analysis of the current state of the science of this important concept has been published. Our literature search revealed 34 research articles that met inclusion criteria. The studies were assessed in terms of conceptualization of (...) mutuality, instrument development, populations studied, research designs and methods and findings. Significant scientific progress during the past 30 years includes the development of clear definitions and new instruments, expansion of research beyond the clinical populations in which mutuality was first studied, the use of a variety of research designs, and increasingly sophisticated methods of data analysis. Growing evidence suggests that mutuality is associated with caregiver emotional health outcomes and may decrease over time in the context of chronic illness. Directions for future research include development of new theoretical frameworks grounded in relational theory, development of theory on the dynamics of mutuality over time, exploration of mutuality in diverse cultures and populations, and intervention studies aimed at enhancing mutuality. (shrink)

Social robots are marketed as human tools promising us a better life. This marketing strategy commodifies not only the labor of care but the caregiver as well, conjuring a fantasy of technoliberal futurism that echoes a colonial past. Against techno-utopian fantasies of a good life as one involving engineered domestic help, I draw here on the techno-dystopian television show Humans (stylized HUMⱯNS) to suggest that we should find our desires for such help unsettling. At the core of my argument is (...) a return of the “uncanny valley” problem, from its reformulation as an engineering/design problem to its origins as a psychosocial symptom of an unresolved, traumatic past. I conclude that our sense of the uncanny may be best understood as a moral capacity that should be honed rather than evaded. (shrink)

Overall, there’s a rich literature on free speech and hate speech. However, there’s been comparatively less discussion on hate speech that brings in empirical psychological and medical evidence on the possible health harms hate speech can have for minorities. I introduce and piece together a set of pre-existing scientific data that’s new to the philosophical literature to help sufficiently establish an argument that governments should ban hate speech. Given the adverse effects hate speech can have on one’s mental and physical (...) health, hate speech causes harm at many times. Since it causes such harm and leads to overridingly negative consequences, the government ought to regulate such speech. (shrink)

The no-miracles argument (Putnam, 1975) holds that science is successful because successful theories are (approximately) true. Frost-Arnold (2010) objects that this argument is unacceptable because it generates neither new predictions nor unifications. It is similar to the unacceptable explanation that opium puts people to sleep because it has a dormative virtue. I reply that on close examination, realism explains not only why some theories are successful but also why successful theories exist in current science. Therefore, it unifies the disparate phenomena.

The other major question in the history of political philosophy besides the issue of distributive justice is what the best form of government is. In Western philosophy, the received view is democracy. However, this paper challenges this thesis by presenting arguments against democracy relying in significant part on empirical data from political science and political psychology. Moreover, it presents a general case for a hybrid view over democracy for the legislative and executive branches that appends a meritocracy or rule by (...) the merited from Eastern philosophy to democracy. (shrink)

In this paper, I suggest a way of resolving the whole-part dilemma suggested in the Parmenides. Specifically, I argue that grabbing the second horn of the dilemma does not pose a significant challenge. To argue for this, I consider two theses about Forms, namely, the oneness and indivisibility theses. More specifically, I argue that the second horn does not violate the oneness thesis if we treat composition as identity and that the indivisibility thesis ought to be reinterpreted given Plato’s later (...) dialogues. By doing so, I suggest a com-positional understanding of Plato’s theory of Forms, which can resolve the whole-part dilemma. (shrink)

Lockdowns, or modern quarantines, involve the use of novel restrictive non-pharmaceutical interventions (NPIs) to suppress the transmission of COVID-19. In this paper, I aim to critically analyze the emerging history and philosophy of lockdowns, with an emphasis on the communication of health evidence and risk for informing policy decisions. I draw a distinction between evidence-based and modeling-based decision-making. I argue that using the normative framework of evidence-based medicine would have recommended against the use of lockdowns. I first review the World (...) Health Organization’s evidence-based pandemic preparedness plans for respiratory viruses. I then provide a very brief history of COVID-19 modeling, which was cited as justification for the use of lockdowns in the U.K., the U.S., and much of the world. I focus on the so-called Imperial College model designed by Neil Ferguson et al. as well as the so-called Oxford model designed by José Lourenço et al. I analyze the evidence-based pandemic response known as ‘mitigation’, and I compare it with Ferguson et al.’s experimental strategy known as ‘suppression’. I summarize the strengths and weaknesses of these strategies based on their diametric aims and each model’s parametric assumptions. Based on my critical analysis of the suppression strategy, I attempt to expose what has been called the ‘logic of lockdowns’, which Sunetra Gupta of the Oxford model group has suggested is flawed. Finally, I consider Trisha Greenhalgh’s objection to evidence-based policy based on the precautionary principle, and I attempt to offer a response. I conclude with a brief narrative review of the emerging randomized evidence on restrictive NPIs, which seems to support my claim that mitigation was the strategy that would have been recommended by evidence-based medicine. If this is true, then COVID-19 modeling may serve as an important reminder of the enduring lesson of evidence-based medicine: that one should always ‘Trust the Evidence!’ for better health policy. (shrink)

Rita Charon says that narrative medicine is about honoring stories of illness. In a system where physicians and patients can often feel as though they are reduced to numbers, narrative medicine is a plea to take the narratives of illness seriously. But what does it mean to honor a story? In this essay, I use the framework of narrative medicine to offer narrative reflections on the concept of honor inspired by on three definitions, including respect, moral rightness, and high regard. (...) I explain how each definition illustrates an aspect of honor and its role as an ethical virtue in narrative medicine. (shrink)

A central question in neuroscience and psychology is how the mammalian brain represents the outside world and enables interaction with it. Significant progress on this question has been made in the domain of spatial cognition, where a consistent network of brain regions that represent external space has been identified in both humans and rodents. In rodents, much of the work to date has been done in situations where the animal is free to move about naturally. By contrast, the majority of (...) work carried out to date in humans is static, due to limitations imposed by traditional laboratory based imaging techniques. In recent years, significant progress has been made in bridging the gap between animal and human work by employing Virtual Reality (VR) technology to simulate aspects of real-world navigation. Despite this progress, the VR studies often fail to fully simulate important aspects of real-world navigation, where information derived from self-motion is integrated with representations of environmental features and task goals. In the current review, we provide a brief overview of animal and human imaging work to date, focusing on commonalties and differences in findings across species. Following on from this we discuss VR studies of spatial cognition, outlining limitations and developments, before introducing mobile brain imaging techniques and describe technical challenges and solutions for real-world recording. Finally, we discuss how these advances in mobile brain imaging technology, provide an unprecedented opportunity to illuminate how the brain represents complex multifaceted information during naturalistic navigation. (shrink)

This brief essay – based partially on remarks made as a member of a "diversity panel" at a recent Florida Philosophical Association meeting and partially on the reception of those remarks – concerns the rhetorical spaces from which one is allowed to speak as a woman in philosophy. I identify two gendered locations from which women are allowed to speak about the diversity problem in philosophy: 1) the happy woman of reason and 2) the unhappy feminist philosopher. Drawing on Marilyn (...) Frye's analysis of the double-bind as a symptom of oppression and Sara Ahmed's reflections on the figure of "the feminist killjoy", I argue that both gendered locales undermine one’s ability to bring about transformative change in the discipline. (shrink)

Social acceptance is assumed to have widespread positive effects on the recipient; however, ethnic/racial minorities often react negatively to social acceptance by White individuals. One possibility for such reactions might be their lack of trust in the genuineness of White individuals’ positive evaluations. Here, we examined the role that oxytocin—a neuropeptide putatively linked to social processes—plays in modulating reactions to acceptance or rejection during interracial interactions. Black participants received intranasal oxytocin or placebo and interacted with a White, same-sex stranger who (...) provided positive or negative social feedback. After positive feedback, participants given oxytocin tended to display approach-oriented cardiovascular responses of challenge, exhibited more cooperative behavior, and perceived the partner to have more favorable attitudes toward them after the interaction. Following negative feedback, oxytocin reduced anger suppression. Oxytocin did not modulate testosterone reactivity directly, but our exploratory analysis showed that the less participants suppressed anger during the interaction with their partner, the greater testosterone reactivity they displayed after the interaction. These results survived the correction for multiple testing with a false discovery rate of 20%, but not with a rate of 10 or 5%. Discussion centers on the interplay between oxytocin and social context in shaping interracial interactions. (shrink)