Background: Despite the growing body of knowledge about surrogate decision making, we know very little about the use of ethical frameworks (including ethical theories, principles, and concepts) to understand surrogates’ day-to-day experiences in end-of-life care planning for incapacitated adults. Objectives and Methods: This qualitative systematic review was conducted to identify the types of ethical frameworks used to address surrogates’ experiences in end-of-life care planning for incapacitated adults as well as the most common themes or patterns found in surrogate decision-making research. (...) Findings: Seven research papers explicitly identified ethical theories, principles, or concepts, such as autonomy, substituted judgment, and best interest standards as guidelines for the research. Surrogate decision making themes included the responsibilities and goals of being a surrogate, factors influencing surrogates’ decision making, outcomes for surrogates, and an overarching theme of “wanting to do the right thing” for their loved one and/or themselves. Discussion: Understanding the complexity of surrogates’ experiences of end-of-life care planning is beyond the scope of conventional ethical frameworks. Conclusion: Ethical frameworks that address individuality and contextual variations related to decision making may more appropriately guide surrogate decision-making research that explores surrogates’ end-of-life care planning experiences. (shrink)

South Korean cultivators share features with counterparts in both the global south and north. This combination of traits has produced a diversity of sources that underpin a food sovereignty movement. A case study of t’ojong, or native, seed activism illustrates how local systems of meaning and particular constellations of interests make food sovereignty appealing to a broad coalition of farmers, consumers, part-time cultivators, agricultural scientists, and activists for farmers and for women. The country’s experience demonstrates that responses to market encroachment (...) on food production provide only part of the force driving food sovereignty movements. (shrink)

This paper discusses two perspectives, each of which recognises the importance of environmental resources in enhancing and amplifying our cognitive capacity. One is the Clark–Chalmers model, extended further by Clark and others. The other derives from niche construction models of evolution, models which emphasise the role of active agency in enhancing the adaptive fit between agent and world. In the human case, much niche construction is epistemic: making cognitive tools and assembling other informational resources that support and scaffold intelligent action. (...) I shall argue that extended mind cases are limiting cases of environmental scaffolding, and while the extended mind picture is not false, the niche construction model is a more helpful framework for understanding human action. (shrink)

Within paleoanthropology, the origin of behavioral modernity is a famous problem. Very large-brained hominins have lived for around half a million years, yet social lives resembling those known from the ethnographic record appeared perhaps 100,000 years ago. Why did it take 400,000 years for humans to start acting like humans? In this article, I argue that part of the solution is a transition in the economic foundations of cooperation from a relatively undemanding form, to one that imposed much more stress (...) on human motivational and cognitive mechanisms. The rich normative, ceremonial, and ideological lives of humans are a response to this economic revolution in forager lives; from one depending on immediate return mutualism to one depending on delayed and third-party reciprocation. (shrink)

This paper presents an emerging aspect of intentionality through recent Artificial Intelligence (AI) developments in art and design. Our main thesis is that, if we focus just on the outcome of the artistic process, the intentionality of the artist does not have any relevance. Intention is measured as a result of actions regardless of whether they are human-based or not as long as there is an esthetical value intersubjectively acknowledged. In other words, what matters is the ‘intentio’ embedded in the (...) work of art (the output) rather than the ‘intendere’ (the process). By considering the former aspect, intentionality becomes free of human intervention, therefore 'unintentional'. This thesis is supported through a range of examples related to AI in general and AI art in particular. However, in the case of a self-driving vehicle, the macro-goal of the system is fixed by humans, even though the AI system itself will take care of decomposing the macro-goal into a set of micro-goals and take the corresponding decisions. In the case of art, the system does not need to have any exterior goal to the extent that art is pure freedom of expression, as many philosophers have acknowledged. In this sense, the decisions of any AI system generating art or design are independent of humans and must be judged only on the ground of the final outcome. A work of art will be judged ‘artistic’ to the extent that humans will recognize an artistic intent in the work itself. In particular, the introduction of random processes makes an AI-generated artwork fully independent of human creativity. (shrink)

Truth-telling in healthcare practice can be regarded as a universal communicative virtue; however, there are different views on what consequence it has for giving or diminishing hope. The aim of this article is to explore the relationship between the concepts of truth-telling and hope from a relational ethics approach in the context of healthcare practice. Healthcare staff protect themselves and others to preserve hope in the care of seriously sick patients and in end-of-life care. This is done by balancing truth-telling (...) guided by different conditions such as the cultural norms of patients, family and staff. Our main conclusion is that the balancing of truth-telling needs to be decided in a mutual understanding in the caring relationship, but hope must always be inspired. Instead of focusing on autonomy as the only guiding principle, we would like to propose that relational ethics can serve as a meaningful perspective in balancing truth-telling. (shrink)

This collection reports on the latest research on an increasingly pivotal issue for evolutionary biology: cooperation. The chapters are written from a variety of disciplinary perspectives and utilize research tools that range from empirical survey to conceptual modeling, reflecting the rich diversity of work in the field. They explore a wide taxonomic range, concentrating on bacteria, social insects, and, especially, humans. -/- Part I (“Agents and Environments”) investigates the connections of social cooperation in social organizations to the conditions that make (...) cooperation profitable and stable, focusing on the interactions of agent, population, and environment. Part II (“Agents and Mechanisms”) focuses on how proximate mechanisms emerge and operate in the evolutionary process and how they shape evolutionary trajectories. Throughout the book, certain themes emerge that demonstrate the ubiquity of questions regarding cooperation in evolutionary biology: the generation and division of the profits of cooperation; transitions in individuality; levels of selection, from gene to organism; and the “human cooperation explosion” that makes our own social behavior particularly puzzling from an evolutionary perspective. (shrink)

In this article, I aim to do two things: first, introduce Juche, the official philosophy of the Democratic People’s Republic of Korea (“North Korea”), and second, defend Juche against Alzo David-West’s allegation that it is a nonsensical philosophy. I organize David-West’s complaints into two major strands—that Juche’s axiom is too vague to be of philosophical use and that Juche makes too stark a distinction between human vs. everything else—and offer responses to both strands. My goal isn’t to defend the regime, (...) but to present its ideology in the most charitable way so its merits and demerits can be seen more clearly in future engagements. (shrink)

In introgressive hybridization (the repeated backcrossing of hybrids with parental populations), Edgar Anderson found a source for variation upon which natural selection could work. In his 1953 review article “Introgressive Hybridization,” he asserted that he was “bringing taxonomy to the service of genetics” whereas distinguished colleagues such as Theodosius Dobzhansky and Ernst Mayr did the precise opposite. His work as a geneticist particularly focused on linkage and recombination and was enriched by collaborations with Missouri Botanical Garden colleagues interested in taxonomy (...) as well as with cytologists C.D. Darlington and Karl Sax. As the culmination of a biosystemtatic research program, Anderson’s views challenged the mainstream of the Evolutionary Synthesis. -/- . (shrink)

This study focuses on CEO hubris and its detrimental effect on corporate financial performance along with an examination of critical corporate governance contingencies that may moderate the negative effect. From 654 observations of 164 Korean firms over the years 2001–2008, we found that CEO power exacerbated the negative effect of CEO hubris on corporate financial performance, whereas board vigilance mitigated it. This study provides empirical evidence that entrenchment problems arising from CEO hubris would be exacerbated as CEOs become more powerful, (...) but weakened as board of directors become more vigilant. Theoretical contributions and practical implications will be discussed. (shrink)

1. Kant on the “Conditions of the Possibility” of Experience -- Claude Piché // 2. Plato and Kantian Transcendental Constructivism -- Tom Rockmore // 3. Kant and Fichte on the Notion of (Transcendental) Freedom -- Violetta L. Waibel // 4. Fichte, Transcendental Ontology, and the Ethics of Belief -- Steven Hoeltzel // 5. Transcendental Philosophy as “Therapy of the Mind”: Fichte’s “Facts of Consciousness” Lectures -- Benjamin D. Crowe // 6. From Transcendental Philosophy to Hegel’s Developmental Method -- William F. (...) Bristow // 7. How Transcendental Is Cohen’s Critical Idealism? -- Halla Kim // 8. Heidegger’s Failure to Overcome Transcendental Philosophy -- Eric S. Nelson // 9. Others as the Ground of Our Existence: Levinas, Løgstrup, and Transcendental Arguments in Ethics -- Robert Stern // 10. Raising Validity Claims for Reasons: Transcendental Reflection in Apel’s Argumentative Discourse -- Matthias Kettner // 11. Transcendental Arguments Based on Question-Answer Contradictions -- Yukio Irie // 12. Consequences of the Transcendental-Pragmatic Consensus Theory of Truth -- Michihito Yoshime // 13. On Jürgen Habermas’s Cognitive Theory of Morality -- Yasuyuki Funaba . (shrink)

In many texts on evolution the reader will find a characteristic depiction of inheritance and evolution, one showing the generations of an evolving population linked only by a causal flow from genotype to genotype. On this view, the genotype of each organism in this population plays a dual role as both the motor of individual development and as the sole causal channel across the generations. This picture is known to be literally false. In many species, parents exert direct causal influence (...) on their offspring, and some of those influences cause the offspring to resemble the parent. For example, a butterfly that lays her eggs on the same plant host on which she hatched thereby exerts a causal influence on her offspring, and one apt to cause them to resemble her more than they would, had she chosen a plant of a different species. None of this is at all controversial, but it poses a puzzle. If the “Weissmanian” conception is literally false, why is it seen as a perspicacious representation of evolution? (shrink)

The articles in this issue represent the pursuit of a new understanding of the human past, one that can replace the neo-saltationist view of a human revolution with models that can account for the complexities of the archaeological record and of human social lives. The articulation of archaeological, philosophical, and biological perspectives seems to offer a strong foundation for exploring available evidence, and this was the rationale for collecting these particular articles. Even at this preliminary stage there is a coherence (...) emerging in proposals: the origin and operation of symbolically rich, complexly signaling human social systems was the consequence of the long-term evolution of multiple components of perceiving and negotiating social interactions, a contingent outcome of myriad adaptive shifts rather than a single event. (shrink)

I claim that the balance of nature metaphoris shorthand for a paradigmatic view of natureas a beneficent force. I trace the historicalorigins of this concept and demonstrate that itoperates today in the discipline of populationecology. Although it might be suspected thatthis metaphor is a pre-theoretic description ofthe more precisely defined notion ofequilibrium, I demonstrate that balance ofnature has constricted the meaning ofmathematical equilibrium in population ecology.As well as influencing the meaning ofequilibrium, the metaphor has also loaded themathematical term with values.Environmentalists (...) and critics use thisconflation of meaning and value to theiradvantage. This interplay between the balanceof nature and equilibrium fits aninteractionist interpretation of the role ofmetaphor in science. However, it seems theinteraction is asymmetric, and the balance ofnature metaphor has had a larger influence onmathematical equilibrium than vice versa. Thisdisproportionate influence suggests that themetaphor was and continues to be a constitutivepart of ecological theories. (shrink)

A queer crip embodied experience of limping is the point of departure for my reflections on the differences between a crip phenomenology and a phenomenology of disability. I argue that a crip phenomenology can further understanding of how ableism and heternormativity work together, along with other structures of violence, to shape experiences at the edges of ability and disability, and, indeed, the possibility of queer crip movement in and through worlds.

Kirk Lougheed argues that active euthanasia (here ‘euthanasia’) is impermissible for people who are extremely sick and cannot exercise their vital forcei because (1) exercising vital force does not require volition but only being an object of caring relationships and (2) African philosophy entails other-regarding deontological duties to stay alive.1 In this commentary, we point out an implication of Lougheed’s view that is morally problematic and offer a revision that avoids this implication. We also argue for an additional advantage of (...) this revision. Lougheed’s view implies that a person who is the object of very few relationships has a much weaker duty to stay alive than a person who is well-loved and the object of many relationships. This is because he seems to think that duties to stay alive are derived entirely from one’s relationship with other people. While he is clear that a person, even if terminally ill or permanently unconscious, has a duty to stay alive so that they could remain the object of harmonious relationships, he is silent on whether duties to stay alive could be grounded in reasons that have to do with oneself. Plausibly, on this view, the strength of one’s duty to stay alive depends solely …. (shrink)

ArgumentHistorians have accorded a privileged status to the analytic ideal of elements as a distinctive marker of “modern” chemistry. Boyle’s and Lavoisier’s have been used to characterize their modernity, which has in turn justified their status as the founding fathers of modern chemistry. It has been difficult, however, to establish a viable connection between these two fathers or the genealogy of their definitions. I argue in this paper that French didactic tradition gave rise to the definition Boyle stated in the (...) Sceptical Chymist, or the analytic/philosophical ideal of elements. He did not endorse the definition he gave, but criticized its lack of analytic rigor and philosophical sophistication. His critique served as a negative heuristic, leading to Nicolas Lemery’s analytic ideal of “chemical principles” as distinct from “natural principles.” Lemery’s definition survived in French didactic tradition, as is evidenced in Macquer’s and Guyton’s textbooks which provided direct precedents for Lavoisier’s analytic ideal of “elements or principles.”. (shrink)

Scholars are becoming increasingly interested in whether and how government use of Big Data will affect public policy outcomes. Despite such growing scholarly interests, however, little evidence exists on the role Big Data can play in improving government service. We undertake one of the first quantitative studies revealing the potential utility and limitations of “Big Data-based policymaking” by exploring its recent use by the Seoul Metropolitan Government. In 2013, the government introduced the “Owl Bus”—a late-night bus system—the routes of which (...) were selected based on government analyses of Big Data relating to citizens’ late-night taxi and mobile phone use. The findings suggest that the average number of passengers utilizing the Owl Bus routes was significantly greater than that on other daytime bus routes with comparable characteristics. That said, we also present the potential limitations of evidence-based policymaking in general, especially when politics and equity considerations are factored in. (shrink)

The psychoanalytical case history was in many ways the pivot point of John Forrester’s reflections on case-based reasoning. Yet the Freudian case is not without its own textual forebears. This article closely analyses texts from two earlier case-writing traditions in order to elucidate some of the negotiations by which the case history as a textual form came to articulate the mode of reasoning that we now call ‘thinking in cases’. It reads Eugène Azam’s 1876 observation of Félida X and her (...) ‘double personality’—the case that brought both Azam and Félida to prominence in late 19th-century French science—against a medico-surgical case penned by the Bordeaux physician in the same decade. While the stylistics of Azam’s medical case mirror its epistemic underpinnings in the ‘vertical’ logics of positivist science, the multiple narratives interwoven in Félida’s case grant both Azam and his patient the role of knowledge-making actors in the text. This narrative transformation chimes with the way Azam reasons ‘horizontally’ from particulars to Félida’s singular condition, but sits in tension with his choice to structure the observation along a ‘vertical’ axis. Between the two, we glimpse the emergence of the psychological observation as a mode of writing and thus of thinking in cases. (shrink)

The term zhen 真 in the Zhuangzi 莊子 is commonly associated with the zhen ren 真人 or "true person." We find metaphorical descriptions such as that he can go through fire and water unharmed. On the other hand, some scholars would claim that there is a more mystical element to the Zhuangzi that is missed if we think that such descriptions are "merely" metaphorical. However, the term zhen is not only applied to the zhen ren, and this essay has the (...) broader aim of investigating its various meanings and uses in the Zhuangzi. We shall situate our understanding of the zhen ren within the context of this broader investigation.Zhen has several applications throughout the text. To begin with, it may be used to affirm that .. (shrink)

While it is well known that Zhuangzi uses metaphor extensively, there is much less appreciation of the role that it plays in his thought-a topic that is investigated in this essay. At the same time, this investigation is closely concerned with questions about the nature of metaphor. Comparisons are made between a central metaphorical structure in the Zhuangzi on the one hand and contemporary views of the nature of metaphor by Donald Davidson and by Lakoff and Johnson on the other. (...) It is hoped that these comparisons will help to illuminate the central metaphorical structure and its role in the philosophy of the Zhuangzi. (shrink)

Somites are transient structures which represent the most overt segmental feature of the vertebrate embryo. The strict temporal regulation of somitogenesis is of critical developmental importance since many segmental structures adopt a periodicity based on that of the somites. Until recently, the mechanisms underlying the periodicity of somitogenesis were largely unknown. Based on the oscillations of c-hairy1 and lunatic fringe RNA, we now have evidence for an intrinsic segmentation clock in presomitic cells. Translation of this temporal periodicity into a spatial (...) periodicity, through somite formation, requires Notch signaling. While the Hox genes are certainly involved, it remains unknown how the metameric vertebrate axis becomes regionalized along the antero–posterior (AP) dimension into the occipital, cervical, thoracic, lumbar, and sacral domains. We discuss the implications of cell division as a clock mechanism underlying the regionalization of somites and their derivatives along the AP axis. Possible links between the segmentation clock and axial regionalization are also discussed. (shrink)

In this essay, I propose an interpretation of John Rawls’s The Law of Peoples that puts the stability of liberal societies as the central organizing idea of its principles. I start by critically examining other interpretations currently found in the literature. I observe two characteristics of Rawls’s conception of stability from his political turn: stability for the right reasons and in the right way. In the main body of the essay, I argue that the absence of a global egalitarian principle (...) is compatible with the stability of liberal peoples, that the toleration of decent peoples is conducive to the stability of liberal peoples, and that the universal enforcement of human rights and assistance to burdened societies are rationally required for the stability of liberal peoples. I clarify the meaning of the centrality of peace and stability, and explain why it is not conspicuous but still unsurprising given Rawls’s personal history and the development of his theory of international justice. I conclude by suggesting how the stability interpretation paves the way for further extensions of Rawls’s theory of justice and assessing the practical value of The Law of Peoples. (shrink)

Perceptual expertise refers to learning that is specific to a domain, that transfers to new items within the trained domain, and that leads to automatic processing in the sense that expertise effects can be measured across a variety of tasks. It can be argued that most of us possess some degree of perceptual expertise in a least one, if not several domains, thereby giving the study of perceptual expertise broad application. Some object categories may in fact be objects of perceptual (...) expertise to the majority of people: Faces appear to be one such example. Thus, the use of face stimuli, or the comparison of face and object perception, can be a powerful way to ask whether a given process is influenced by perceptual expertise. Here, we emphasize one characteristic way that face processing appears to differ from nonface processing: that is, the degree to which they recruit a “holistic” rather than a “featural” perceptual strategy. This review brings evidence that expertise influences perceptual processing together with recent findings that the capacity of visual short-term memory is greater in perceptual experts and explores the relationship between the two. (shrink)

The issue of human nature or xing 性 was a major philosophical topic of the mid- and late-Warring States period of ancient China. It was famously discussed, for example, in the Mencius. Zhuangzi 莊子 lived around the same time as Mencius and one might expect that he, too, would have discussed it. Surprisingly, the term xing is absent from the Inner Chapters of the Zhuangzi. There have been different responses to this, namely, that Zhuangzi: used different terms equivalent to xing; (...) believed that human nature is bad (despite not mentioning xing); was deliberately silent on xing as an oblique way of criticizing others such as Mencius. I review these claims and provide an analysis of how xing was mainly conceptualized during the Warring States period in essentialist terms. I shall read Zhuangzi’s philosophy as transcending this conceptual framework. Instead of a theory of human nature, Zhuangzi provides stories and descriptions of the different facets of human behavior and their psychological and other complexities. These often have an epistemic focus that stand independently of any theory of human nature. (shrink)

What do events such as scandals, industrial accidents, activist threats, and mass shootings have in common? They can all trigger an audience’s stigma judgment about the organization involved in the event. Despite the prevalence of these stigma-triggering events, management research has provided little conceptual work to characterize the dimensions and processes of organizational event stigma. This article takes the perspective of the evaluating audience to unpack the stigma judgment process, identify critical dimensions for categorizing types of event stigma, and explore (...) the role of the stigmatizers’ aesthetic, emotional, and cognitive reactions as well as their practical considerations in producing what we call “sticky stigmas.” Our event stigma typology provides clarity regarding how stigmas differ based on the types of events and audiences’ reactions and why some event stigmas are stronger and more long-lasting than others. We highlight the role of emotions and aesthetics in stigma formation and the various ethical dilemmas that influence stigma stickiness. (shrink)

This paper surveys recent philosophy of biology. It aims to introduce outsiders to the field to the recent literature (which is reviewed in the footnotes) and the main recent debates. I concentrate on three of these: recent critiques of the replicator/vehicle distinction and its application to the idea of the gene as the unit of section; the recent defences of group selection and the idea that standard alternatives to group selection are in fact no more than a disguised form of (...) group selection; and recent ideas on the role of selection in evolution, especially the role of selection in structuring the large-scale history of life. The paper connects philosophy of biology to some more general problems in the philosophy of science, and concludes with a few suggestions about unfinished business. (shrink)

The term “legacy effect” has been used in ecology since the early 1990s by authors studying plant succession, invasive-plant impacts, herbivory impacts, ecosystem engineering, and human land-use impacts. Although there is some variability in usage, the term is normally used to describe impacts of a species on abiotic or biotic features of ecosystems that persist for a long time after the species has been extirpated or ceased activity and which have an effect on other species. For example, human agricultural activities (...) may have a legacy effect on soil structure and vegetative communities that lasts for centuries and which alters current communities. The concept may be related to the idea of ecological inheritance in evolutionary biology but would refer only to a subset of the features of this concept. In particular, legacy effects could refer to those kinds of ecological inheritance where a physical or biological change in ecosystem state is caused by one species, where this change persists after the extirpation of the causal species and alters selection pressure of another species much later in time. (shrink)

ABSTRACTThis study assessed the knowledge and perception of human biological materials and biorepositories among three study groups in South Korea. The relationship between the knowledge and the perception among different groups was also examined by using factor and regression analyses. In a self‐reporting survey of 440 respondents, the expert group was found more likely to be knowledgeable and positively perceived than the others. Four factors emerged: Sale and Consent, Flexible Use, Self‐Confidence, and Korean Bioethics and Biosafety Action restriction perception. The (...) results indicate that those who are well aware of the existence of biobanks were more positively inclined to receive the Sale and Consent perception. As a result of the need for high quality HBMs and the use of appropriate sampling procedures for every aspect of the collection and use process, the biorepository community should pay attention to ethical, legal, and policy issues. (shrink)

Despite advances in treatments over the last decades, a uniformly reliable and free of side effects therapy of human cancers remains to be achieved. During chromosome replication, a premature halt of two converging DNA replication forks would cause incomplete replication and a cytotoxic chromosome nondisjunction during mitosis. In contrast to normal cells, most cancer cells bear numerous DNA deletions. A homozygous deletion permanently marks a cell and its descendants. Here, we propose an approach to cancer therapy in which a pair (...) of sequence‐specific roadblocks is placed solely at two cancer‐confined deletion sites that are located ahead of two converging replication forks. We describe this method, termed “replication blocks specific for deletions” (RBSD), and another deletions‐based approach as well. RBSD can be expanded by placing pairs of replication roadblocks on several different chromosomes. The resulting simultaneous nondisjunctions of these chromosomes in cancer cells would further increase the cancer‐specific toxicity of RBSD. (shrink)

This paper critiques the rise of scientific approaches to central questions in the humanities, specifically questions about human nature, ethics, identity, and experience. In particular, I look at how an increasing number of philosophers are turning to evolutionary psychology and neuroscience as sources of answers to philosophical problems. This approach constitutes what I term a biological turn in the humanities. I argue that the biological turn, especially its reliance on evolutionary psychology, is best understood as an epistemology of ignorance that (...) contributes to a climate of hostility and intolerance regarding feminist insights about gender, identity, and the body. (shrink)