The term “synthetic biology” is a popular label of an emerging biotechnological field with strong claims to robustness, modularity, and controlled construction, finally enabling the creation of new organisms. Although the research community is heterogeneous, it advocates a common denominator that seems to define this field: the principles of rational engineering. However, it still remains unclear to what extent rational engineering—rather than “tinkering” or the usage of random based or non-rational processes—actually constitutes the basis for the techniques of synthetic biology. (...) In this article, we present the results of a quantitative bibliometric analysis of the realized extent of rational engineering in synthetic biology. In our analysis, we examine three issues: (1) We evaluate whether work at three levels of synthetic biology (parts, devices, and systems) is consistent with the principles of rational engineering. (2) We estimate the extent of rational engineering in synthetic biology laboratory practice by an evaluation of publications in synthetic biology. (3) We examine the methodological specialization in rational engineering of authors in synthetic biology. Our analysis demonstrates that rational engineering is prevalent in about half of the articles related to synthetic biology. Interestingly, in recent years the relative number of respective publications has decreased. Despite its prominent role among the claims of synthetic biology, rational engineering has not yet entirely replaced biotechnological methods based on “tinkering” and non-rational principles. (shrink)

Ever since the publication of Read’s The Politics of Transindividuality (2015), the academic interest in transindividuality has steadily mounted. In this conversation, Bram Wiggers and Jason Read discuss the current state of affairs around the concept of transindividuality. The conversation begins with a definition of transindividuality and discusses what sets the term apart from other philosophies of social individuation. Having defined the concept of transindividuality, the conversation then engages with the question of how transindividuality can be adopted as a means (...) of social-political critique. First, Bram and Jason discuss how transindividuality is evoked but not explicitly mentioned in the social-political critiques of Spinoza and Marx. Secondly, the conversation takes up the social-political critiques of Paolo Virno and Bernard Stiegler who make explicit use of transindividuality. Central to the later parts of the conversation is the complicated interrelation between the political and economic domains of individuation, as well as the tendency of collective modes of representation to be effaced and obscured by (neoliberal) individualism and the post-Fordist conditions of labor. Overall, the conversation highlights the relevance of transindividuality for social-political philosophical critique. (shrink)

Is phenomenology a method or a philosophy (of ?ontological? character)? This question is discussed here with a recent philosophical collection of articles about the phenomenology of sport at hand. However, one finds very few concrete phenomena in this volume, but much abstract talk about the authoritative philosophers of ontology and existentialism. This gives the ?phenomenological school? a somewhat sectarian character, which is not typical in recent contributions of phenomenology. This review essay broadens out from the current volume under consideration towards (...) a history of phenomenology and a differential phenomenology of phenomenology. It is not clear how much value the volume itself, however, has for the understanding of sport as well as for the understanding of phenomenology. Nevertheless, it documents how phenomenological scholastics approach sport, which may serve as a warning at a time when positivist reductionism seems to have also become mainstream in human and social sciences. (shrink)

English summary: Human perception includes the division of space into left and right. In general, left holds a negative connotation: A clumsy man appears linkisch in German, links meaning left, and the term translates as awkward. If you conned him, he has been gelinkt. For a long time this negative coloring was also closely associated with the image of left-handers: Left-handers were often regarded as disabled, appeared awkward and antisocial, and were exposed to discrimination. To understand the people of ancient (...) Greece and Rome, one must understand the role right and left played in their perception and evaluation of the world. Henning Wirth studies the following questions from an ancient historical perspective: How did the Greeks and Romans perceive left? What role was provided to the left hand in a dominantly right-handed world, where the right hand attested Godly effectiveness? And how does one explain the phenomenon of left-handedness and assessment of left-handed people? German text. German description: Zur menschlichen Wahrnehmung gehort die Einteilung des Raumes in links und rechts. Dabei ist links in der Regel negativ konnotiert: Ein ungeschickter Mensch erscheint alinkisch. Hat man ihn betrogen, so hat man ihn agelinkt. Lange Zeit war diese Negativfarbung auch eng mit dem Bild ueber Linkshander verknuepft: Linkshander galten oftmals als behindert, erschienen asozial und ungeschickt und waren Diskriminierungen ausgesetzt. Will man den Menschen der griechischen und romischen Antike verstehen, muss man nachvollziehen, welche Rolle rechts und links in seiner Wahrnehmung und Bewertung der Welt spielten. Aus althistorischer Perspektive untersucht Henning Wirth hier folgende Fragen: Welche Vorstellungen besassen Griechen und Romer von links' Welche Rolle war in einer mehrheitlich aus Rechtshandern bestehenden Welt, in der der rechten Hand gottliche Wirkkraft attestiert wurde, fuer die linke Hand vorgesehen' Und wie erklarte man sich das Phanomen der Linkshandigkeit und bewertete linkshandige Menschen'. (shrink)

Tempest Henning ABSTRACT: This paper critically examines non-adversarial feminist argumentation model specifically within the scope of politeness norms and cultural communicative practices. Asserting women typically have a particular mode of arguing which is often seen as ‘weak’ or docile within male dominated fields, the model argues that the feminine mode of arguing is actually more...

Nothingness addresses one of the most puzzling problems of physics and philosophy: Does empty space have an existence independent of the matter within it? Is "empty space" really empty, or is it an ocean seething with the creation and destruction of virtual matter? With crystal-clear prose and more than 100 cleverly rendered illustrations, physicist Henning Genz takes the reader from the metaphysical speculations of the ancient Greek philosophers, through the theories of Newton and the early experiments of his contemporaries, (...) right up to the current theories of quantum physics and cosmology to give us the story of one of the most fundamental and puzzling areas of modern physics and philosophy. (shrink)

In seinem Beitrag „Paul Natorp über das Verhältnis von Philosophie und Psychologie“ stellt Henning Peucker im Ausgang von Hegel und in seiner Gegenüberstellung zu Kant erst einmal die unterschiedlichen Aufgaben von Philosophie und Wissenschaft heraus. Denn während die Wissenschaften um Objektivierung, immer exaktere Gegenstandsbestimmungen bemüht sind, fällt der Philosophie die Aufgabe zu, nach den Möglichkeiten solcher Erkenntnisse zu fragen und diese zu sichern. Von dieser Unterscheidung aus wendet sich Peucker der Bestimmung des Verhältnisses von Philosophie und Psychologie zu. Gleichsam (...) stellt er die Frage nach dem der Psychologie eigentümlichen Charakter und ihrem Gegenstand. Dieser Charakter gründet sich darauf, dass sich das Subjekt nach Natorp nicht wie andere Gegenstände objektivieren lässt. Was aber, so fragt Peucker, kann dann als Gegenstand der Psychologie gelten. Um dieser Frage nachzugehen, weist Peucker auf die drei Momente hin, welche das „Faktum des bewussten Erlebens“ ausmachen, nämlich das erlebende Subjekt, der erlebte Gegenstand und das Verhältnis beider zueinander. Dabei stellt Peucker heraus, dass allein der Inhalt für eine psychologische Untersuchung geeignet ist. Anders allerdings als in den Wissenschaften geht es in der Psychologie nicht um Objektivierung desselben, sondern um eine in entgegengesetzter Richtung ablaufende Subjektivierung, verstanden als Rekonstruktion der kategorialen Voraussetzungen einer jeweiligen Objektivierung. (shrink)

In this paper, I review some of the discussions on procreative beneficence and procreative autonomy in the context of postponed motherhood and compare the considerations to the context of advanced paternal age. In doing so, I will give an overview of the main scientific findings with regard to how older age in men affects the health of future offspring. I shall demonstrate how the discrepancy between the media coverage and policies on postponed motherhood and postponed fatherhood mistakenly suggests that women (...) are more responsible than men for the health of offspring. (shrink)

Erarbeitet von Dominik Balg, Anne Burkard, Henning Franzen, Aenna Frottier, David Lanius, David Löwenstein, Hanna Lucks, Kirsten Meyer, Donata Romizi, Katharina Schulz, Stefanie Thiele und Annett Wienmeister. -/- Die Entwicklung argumentativer Fähigkeiten ist ein zentrales Ziel des Ethik- und Philosophieunterrichts, ja überhaupt ein zentrales Bildungsziel. Wie aber kann das gelingen? In vielen verfügbaren Unterrichtsmaterialien werden argumentative Fähigkeiten eher vorausgesetzt als systematisch gefördert. Auch curriculare Vorgaben bleiben zumeist sehr unspezifisch. Lehrpersonen werden so weitgehend allein gelassen mit der Aufgabe, Lernende beim (...) Erwerb argumentativer Fähigkeiten zu fördern. Die vorliegende Aufgabensammlung soll dazu beitragen, diese Lücke zu schließen. Sie bietet Lehrpersonen reichhaltige Materialien für die spiralcurricular angelegte, systematische Förderung argumentativer Fähigkeit anhand exemplarischer Inhalte. Orientiert an klaren fachlichen Standards finden sich hier Aufgaben auf vier Niveaustufen, jeweils in Verbindung mit übersichtlichen Merkblättern. Die Aufgaben der beiden unteren Niveaustufen lassen sich bereits für jüngere Lernende der Sekundarstufe einsetzen, Aufgaben der obersten Niveaustufe richten sich an Lernende von Abschlussklassen oder der Studieneingangsphase. Für die Hand der Lehrpersonen werden die Aufgaben und Merkblätter durch fachliche und didaktische Kommentare sowie Lösungshinweise ergänzt. (shrink)

The 'Reaction experiment with Hipp chronoscope' is one of the classical experiments of modern psychology. This paper investigates the technological contexts of this experiment. It argues that the development of time measurement and communication in other areas of science and technology (astronomy, the clock industry) were decisive for shaping the material culture of experimental in psychology. The chronoscope was constructed by Matthaus Hipp (1813-1893) in the late 1840s. In 1861, Adolphe Hirsch (1830-1901) introduced the chronoscope for measuring the 'physiological time' (...) of astronomical observers. Hirsch's observatory at Neuchatel (Switzerland) served to control the quality of clocks produced in the nearby Jura mountains. Hipp provided the observatory with a telegraphic system that sent time signals to the centers of clock production. Time telegraphy constituted the stable surroundings of the reaction time experiments carried out by both astronomers and psychologists. This technology permitted precise measurements of short time intervals and offered to Hirsch, as well as to Wilhelm Wundt (1832-1920), a useful metaphor for conceptualizing their respective 'epistemic objects'. But time telegraphy also limited the possibilities of the experimental work conducted within its framework. In particular, noise from outside and inside the research sites at Neuchatel, Leipzig and elsewhere disturbed the precise communication of time. (shrink)

Conceptualizing intelligence in its biological context, as the expression of manifold adaptations, compels a rethinking of measuring this characteristic in humans, relying also on animal studies of analogous skills. Mental manipulation, as an extension of object manipulation, provides a continuous, biologically based concept for studying G as it pertains to individual differences in humans and other species.

The article conducts an analysis of everyday notions of witnessing as emerging from the marginal writings of a mid-twentieth century Belgian medievalist, François Louis Ganshof (1895-1980). The aim of the analysis is threefold: to explore a specific set of cultural conditions shaping the understanding of witnessing; to demonstrate the primacy, in witnessing, of an intricate notion of historicity as moulded by scholarly practice; and to indicate that, and in what manner, witnessing and historicity informed a notion of political experience that (...) appears foundational to Ganshof's understanding of, and attitude towards, matters political in general. The article also stipulates the legitimacy and the value, in a historical investigation of political thought, of focusing on minor figures, discursive patterns and events of seeming insignificance. It ultimately proposes that the small-scale cultural labour on the discursive formations centred on historicity may be deployed for rethinking our understanding of epochal concepts such as modernity. (shrink)

Many authors in ethics, economics, and political science endorse the Lottery Requirement, that is, the following thesis: where different parties have equal moral claims to one indivisible good, it is morally obligatory to let a fair lottery decide which party is to receive the good. This article defends skepticism about the Lottery Requirement. It distinguishes three broad strategies of defending such a requirement: the surrogate satisfaction account, the procedural account, and the ideal consent account, and argues that none of these (...) strategies succeed. The article then discusses and discharges some remaining grounds for resistance to these skeptical conclusions, as well as the possibility of defending a weaker version of a normative lottery principle. The conclusion is that we have no reason to believe that where equal claims conflict, we are morally required to hold a lottery, as opposed to simply picking one of the parties on more subjective grounds or out of pure whim. In addition to the practical consequences of this skeptical view, the article sketches some theoretical implications for debates about saving the greater number and about axiomatic utilitarianism. (shrink)

Methods Young healthy heterosexual couples underwent sleep-lab-based polysomnography of two sleeping arrangements: individual sleep and co-sleep. Individual and dyadic sleep parameters (i.e., synchronization of sleep stages) were collected. The latter were assessed using cross-recurrence quantification analysis. Additionally, subjective sleep quality, relationship characteristics, and chronotype were monitored. Data were analyzed comparing co-sleep vs. individual sleep. Interaction effects of the sleeping arrangement with gender, chronotype, or relationship characteristics were moreover tested. Results As compared to sleeping individually, co-sleeping was associated with about 10% (...) more REM sleep, less fragmented REM sleep (p = 0.008), longer undisturbed REM fragments (p = 0.0006), and more limb movements (p = 0.007). None of the other sleep stages was significantly altered. Social support interacted with sleeping arrangement in a way that individuals with suboptimal social support showed the biggest impact of the sleeping arrangement on REM sleep. Sleep architectures were more synchronized between partners during co-sleep (p = 0.005) even if wake phases were excluded (p = 0.022). Moreover, sleep architectures are significantly coupled across a lag of ± 5min. Depth of relationship represented an additional significant main effect regarding synchronization, reflecting a positive association between the two. Neither REM sleep nor synchronization was influenced by gender, chronotype, or other relationship characteristics. Conclusion Depending on the sleeping arrangement, couple's sleep architecture and synchronization show alterations that are modified by relationship characteristics. We discuss that these alterations could be part of a self-enhancing feedback loop of REM sleep and sociality and a mechanism through which sociality prevents mental illness. (shrink)

ABSTRACTThe purpose of the study was to investigate differences in writers’ abilities to perceive global text organisation in self-, peer- and teacher/researcher-authored essays. Eight student part...

CSR has become an important element in the business strategy of a growing number of companies worldwide. A large number of initiatives have been developed that aim to support companies in developing, implementing, and communicating about CSR. The Global Compact (GC), initiated by the United Nations, stands out. Since its launch in 2000, it has grown to about 2900 companies and 3800 members in total. The GC combines several mechanisms to support CSR strategies: normative principles, networks for learning and co-operation, (...) and communication and transparency about CSR activities. However, up to now only a few empirical evaluations of the contribution of the GC to CSR strategies have been conducted that however have not differentiated between different types of companies (regarding type of industry or regarding the maturity of CSR). This paper aims to partly fill this knowledge gap by a case study examination of three frontrunner companies in the telecommunications industry. The results show that the GC is only one of the many initiatives that these companies employ in shaping, implementing, and reporting about their CSR strategies, and that its role is at most modest. There are two important reasons. One is that many of the CSR issues that these companies deal with are industry specific and are hence addressed in specific networks. The second reason is that the GC principles are perceived as minimum requirements that do not provide many incentives to the three case study companies to perform better. A differentiation of norms for GC members is expected to enhance the contribution of the GC to CSR strategy employment, not only for frontrunner companies but as well for other categories of companies. (shrink)