An architect and architectural philosopher, Berlage created a series of buildings and a body of writings that probed the problems and possibilities of Modernism. His principal texts, given here in English for the first time, present a vital chapter in the history of European Modernism.

In this paper, we first classify different types of second opinions and evaluate the ethical and epistemological implications of providing those in a clinical context. Second, we discuss the issue of how artificial intelligent could replace the human cognitive labour of providing such second opinion and find that several AI reach the levels of accuracy and efficiency needed to clarify their use an urgent ethical issue. Third, we outline the normative conditions of how AI may be used as second opinion (...) in clinical processes, weighing the benefits of its efficiency against concerns of responsibility attribution. Fourth, we provide a ‘rule of disagreement’ that fulfils these conditions while retaining some of the benefits of expanding the use of AI-based decision support systems in clinical contexts. This is because the rule of disagreement proposes to use AI as much as possible, but retain the ability to use human second opinions to resolve disagreements between AI and physician-in-charge. Fifth, we discuss some counterarguments. (shrink)

Hendrik Lorenz presents a comprehensive study of Plato's and Aristotle's conceptions of non-rational desire. They see this as something that humans share with animals, and which aims primarily at the pleasures of food, drink, and sex. Lorenz explores the cognitive resources that both philosophers make available for the explanation of such desires, and what they take rationality to add to the motivational structure of human beings. In doing so, he finds conceptions of the mind that are coherent and deeply (...) integrated with both philosophers' views about such topics as the relation between body and soul, or the nature of the virtues. (shrink)

This festschrift collects a number of insightful essays by a group of accomplished Christian scholars, all of who have either worked with or studied under Hendrik Hart during his 35-year tenure as Senior Member in Systematic Philosophy at the Institute for Christian Studies, Toronto, Canada.

""Catching Ourselves in the Act" is no less than an attempt to explain intelligence. Delightful how the author dismantles traditional views in.

We analyze investors’ perception and long-term effects of board gender diversity on firms’ stock market performance in an international setting. Our results, controlling for the endogenous nature of board compositions, indicate that female board representation neither improves nor reduces firms’ long-term stock performance. Hence, we argue that it is imperative to go beyond the conventional thinking in terms of the business case for gender diversity and broaden the perspective also to incorporate societal and ethical aspects in the strive to board (...) gender equality. Even more so, as our results show that it does not entail reduced shareholder value, which the literature on mandatory gender quotas commonly seems to suggest. (shrink)

Pragma-dialectical approaches to legal argumentation seem to be rather different from traditional approaches appealing to standards of propositional logic. Pragma-dialectical analysis of arguments by analogy and e contrario seem to fall foul to the rigors of logical analysis, in which problems or even concepts of analogy and e contrario seem to disappear. The brunt of both types of special legal argumentation appears to be borne by often implicit general principles and an appeal to the system of the law as a (...) whole. Still, pragma-dialectics and logical analysis of legal argument are best seen as fruitfully supplementing each other in ongoing research of ever evolving legal argument. (shrink)

With special attention being paid to recent developments in Artificial Intelligence and the Law, specifically related to evidentiary reasoning, this book ...

Conflicts in Interpretation applies novel methods of constraint interaction, derived from connectionist theories and implemented in linguistics within the framework of Optimality Theory, to core semantic and pragmatic issues such as polysemy, negation, (in) definiteness, focus, anaphora, and rhetorical structure. It explores the hypothesis that a natural language grammar is a set of potentially conflicting constraints on forms and meanings. Moreover, it hypothesizes that competent language users not only optimize from an input form to the optimal output meaning for this (...) form, or vice versa, but also consider the opposite direction of optimization, thus taking into account the speaker as a hearer and taking into account the hearer as a speaker. The book aims to show that such a bidirectional constraint-based grammar sheds new light on the relation between form and meaning, within a sentence as well as across sentence boundaries, within a single language as well as across languages, and within competent adult language users as well as during language development. An important dimension of the book is the structured investigation of issues at the interface of semantics with syntax and pragmatics, such as the effects of distinguishing between speaker's perspective and hearer's perspective in comprehension and production, stable and instable patterns of form and meaning across languages, and the development of a coherent pattern of form and meaning in children. Conflicts in Interpretation will be of interest to any researcher or advanced student in linguistics, cognitive science, language typology, or psycholinguistics who is interested in the capacity of our human mind to map meaning onto form, and form onto meaning. (shrink)

This paper explores the role and resolution of disagreements between physicians and their diagnostic AI-based decision support systems. With an ever-growing number of applications for these independently operating diagnostic tools, it becomes less and less clear what a physician ought to do in case their diagnosis is in faultless conflict with the results of the DSS. The consequences of such uncertainty can ultimately lead to effects detrimental to the intended purpose of such machines, e.g. by shifting the burden of proof (...) towards a physician. Thus, we require normative clarity for integrating these machines without affecting established, trusted, and relied upon workflows. In reconstructing different causes of conflicts between physicians and their AI-based tools—inspired by the approach of “meaningful human control” over autonomous systems and the challenges to resolve them—we will delineate normative conditions for “meaningful disagreements”. These incorporate the potential of DSS to take on more tasks and outline how the moral responsibility of a physician can be preserved in an increasingly automated clinical work environment. (shrink)

Aristotle takes practical wisdom and arts or crafts to be forms of knowledge which, we argue, can usefully be thought of as ‘empiricist’. This empiricism has two key features: knowledge does not rest on grasping unobservable natures or essences; and knowledge does not rest on grasping logical relations that hold among propositions. Instead, knowledge rests on observation, memory, experience and everyday uses of reason. While Aristotle’s conception of theoretical knowledge does require grasping unobservable essences and logical relations that hold among (...) suitable propositions, his conception of practical and productive knowledge avoids such requirements and is consistent with empiricism. (shrink)

Translation:Hendrik Josephus POS, „Phénoménologie et linguistique.“ In: Keur uit de verspreide geschrift en van Dr. H. J. Pos. Vol. I. Assen: Van Loghum Slaterus 1957, p. 131–141.

When heterogeneous players make strategic investment decisions in multi-stage contests, they might conserve resources in a current contest to spend more in a subsequent contest, if the degree of heterogeneity in the current contest is sufficiently large. We confirm these predictions using data from German professional soccer, in which players are subject to a one-match ban if they accumulate five yellow cards. Players with four yellow cards facing the risk of being suspended for the next match are less likely to (...) be fielded when the heterogeneity in the current match increases and more likely to receive a fifth yellow card in the current match when heterogeneity in the next match increases or heterogeneity in the next match but one decreases. (shrink)

Since the late nineties there has been an increased interested in probabilistic logic learning, an area within AI that combines machine learning with logic-based knowledge representation and uncertainty reasoning. Several different formalisms for combining first-order logic with probability reasoning have been proposed, and it has been studied how models in these formalisms can be automatically learned from data. -/- This talk starts with a brief introduction to probabilistic logic learning, after which we will focus on a relatively new formalism known (...) as CP-logic. CP-logic stands for “causal probabilistic logic”. It is a knowledge representation formalism that allows us to write down rules that indicate that a certain combination of conditions may cause certain effects with a particular probability (e.g., tossing a coin may cause a result of heads or tails, each with 50% probability). Besides the fact that this formalism is interesting for knowledge representation in itself, it also offers interesting opportunities from the machine learning point of view. Indeed, given the semantics of these CP-logic programs, learning them from data amounts to extracting probabilistic causal influences from data. We will discuss recent research on learning CP-logic programs, including: algorithms for learning them; how they relate to graphical models; and applications of learning CP-logic programs. (shrink)

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When Immanuel Bekker, the editor to whom Aristotle owes his page numbers, travelled to Paris in search of manuscripts between 1810 and 1812, Theognis had been a mainstay of classical scholarship for many hundreds of years. Even so, the small tenth-century parchment volume Bekker discovered there came as a surprise. Not only did it contain a text of theTheognideawhich was four hundred years older than the earliest codex known so far; it also added an entirely new section of 176 lines. (...) Presented by the scribe as ‘book 2’ of theElegiac Poemsby Theognis, they revolved around the theme of pederastic love – until then a topic not usually associated with the moralist from Megara. In spite of their similarities to what had now turned into ‘book 1’, they were dismissed as a late forgery almost instantly after Bekker's 1815 edition. Although that view came to be challenged later and can now be considered obsolete, even van Groningen's first comprehensive commentary to theTheognidea, published in 1966 and not superseded since, breaks off where the second book would have begun. Until today, research on this part of the Theognidean corpus has not grown much beyond a trickle flowing at some distance from the classical mainstream. (shrink)

Retinoids play an important role in development and differentiation(1,2). Their effect is mediated through nuclear receptors, RAR (α, β and γ) and RXR (α, β and γ),Abbreviations. RAR: retinoic acid receptor; RXR: retinoid X receptor; T3:thyroid hormone receptor; VD3R: vitamin D3 receptor; PPAR: peroxisome proliferator activated receptor; EcR ecdycsone receptor; USP, ultraspiracle; NGFI‐B: also referred to as nur77a; ELP: embryonal long terminal repeat‐binding protein; FTZ‐F1: positive regulator of the fushi tarazu gene in blastodermstage embryos of Drosophila melanogaster; GR: glucocorticoid receptor; (...) ER: estrogen receptor; RARE, retinoic acid response element; PR: progesterone receptor; DR+x: direct repeat with a spacing of x nucleotides; DBD: DNA‐binding domain; CRABP I and II: cellular retinoic acid binding protein type I and II, respectively; MoMLV: Moloney Murine Leukemia Virus; TBP: TATA‐binding protein; TAF: TBP associated factor. which are members of a distinct subclass (hereafter referred to as type II) of the nuclear receptor superfamily that includes the thyroid hormone receptor (T3R), the vitamin D3 receptor (VD3R) and the peroxisome proliferator activated receptor (PPAR). Type II receptors transactivate through binding sites composed of closely related half‐sites (consensus sequence AGG/T TCA) arranged as direct repeats and, with the possible exception of RXR, do not bind to their cognate binding sites as homodimers but require RXR for high affinity binding. RXR thus provides a link between biologically distinct ligand induced pathways and is a potential target for cross‐regulation. In addition, RAR can utilize alternative routes to enhance transcription initiation mediated through transcriptional co‐activators which are expressed in a cell‐type specific manner. (shrink)

Large Language Models are one of the most prominent examples of current uses of AI, and one of the most urgently pursued normative tasks is to make them and their interactive user-interfaces—open-domain chatbots—safe. However, in this paper, we elaborate first on why such a limited view on the permissibility and desirability of their utterances falls conceptually flat, is philosophically insufficient, and leads to severe technological limits. We then propose a positive normative concept, appropriateness, that can provide the required orientation for (...) determining what chatbots may or may not say, and distinguish between technical-discursive, social, and moral appropriateness. Lastly, we explore the requirements for social and conversational contexts to fulfill appropriateness-requirements, and find that positionality is a key element for their position in discourse. (shrink)

This contribution is a review article on the three most important books by F. Gerrit Immink in practical theology. His approach to this discipline is studying faith praxis of the Protestantse Kerk in Nederland which is a church in the Reformed tradition. In his first book he explained his approach to practical theology in a discussion with the action theory and hermeneutical-communucative approaches. His choice for the study of faith praxis opens the way for a more theological approach to him (...) in which communication between God and people is an important aspect. His second book forms the central part of this article. He uses the concept performance in the liturgy which is adopted from the theater world. In the performance by means of the execution of the liturgy by the congregation they all get involved in the message from the Bible of that Sunday, they are touched by it, it has an effect on them, and they get a new perspective on the problems of everyday life. This is possible through the work of the Holy Spirit. The epiclese prayers in the liturgy are prayers for the enlightening and work by the Spirit. He discusses singing, praying, preaching, baptism and Holy Communion in detail. The main idea is that the performance in the liturgy does something to you, it has an effect on you, something happens to you. To my mind there is no need to choose between the ritual approach and the approach he is putting on the table. The approaches can enrich each other. (shrink)

The present paper studies the general implications of theprinciple of compositionality for the organization of grammar.It will be argued that Janssen''s (1986) requirement that syntax andsemantics be similar algebras is too strong, and that the moreliberal requirement that syntax be interpretable into semanticsleads to a formalization that can be motivated and applied more easily,while it avoids the complications that encumber Janssen''s formalization.Moreover, it will be shown that this alternative formalization evenallows one to further complete the formal theory of compositionality, inthat (...) it is capable of clarifying the role played by translation,model-theoretic interpretation and meaning postulates,of which the latter two aspects received little or no attention inMontague (1970) and Janssen (1986). (shrink)

This article argues that autistic people occasionally experience greater comfort from imposed routines than from a yielding form of love and understanding, which I will call naive humanism. Collins's theory of action, with its attention toward the achievements residing in a reductionist approach, can help to point out the flaws of a naive humanistic stance. It would, however, be a mistake to stop at this point and remain satisfied with the problem-solving capacity of such a reductionist stance. In a ward (...) for autistic youths, the risk of cruelty resides in a purely mechanistic stance as much as in a naive humanistic approach. Thus, the social context of care of autistic people urges us to question the scope of a traditional scheme of thought, which cherishes a deep distinction between humans and machines. (shrink)

The revised edition contains a new chapter which provides an elegant description of the semantics. The various classes of lambda calculus models are described in a uniform manner. Some didactical improvements have been made to this edition. An example of a simple model is given and then the general theory (of categorical models) is developed. Indications are given of those parts of the book which can be used to form a coherent course.

The reliability of clinical practice guidelines has been disputed because guideline panel members are often burdened with financial conflicts of interest. Current recommendations for COI regulation advise not only detailed declaration but also active management of conflicts. To continuously assess COI declaration and management in German guidelines we established the public database LeitlinienWatch. We analyzed all German guidelines at the highest methodological level that included recommendations for pharmacological therapy according to five criteria: declaration and assessment of COI, composition of the (...) guideline development group, independence of the coordinators and lead authors, imposed abstentions because of COI and public external review. Each criterion was assessed using predefined outcome categories. Most guidelines contained a detailed declaration of COI. However, none of the guidelines provided full transparency of COI assessment results. The guideline group was composed of a majority of participants with COI in 55% of the guidelines, no guideline was free of participants with COI. Only 9% of guidelines had coordinators and lead authors without any financial COI. Most guidelines did not provide a rule for abstentions for participants with COI. In 21% of guidelines there was a rule, but abstentions were either not practiced or not documented, whereas in 7% partial abstentions and in 2% complete abstentions were documented. Two thirds of the guideline drafts were not externally reviewed via a public website. COI are usually documented in detail in German guidelines of the highest methodological level. However, considerable improvement is needed regarding active management of COI, including recruitment of independent experts for guideline projects, abstention from voting for participants with COI and external review of the guideline draft. We assume that the publicly available ratings on GuidelineWatch will improve the handling of conflicts of interest in guideline development. (shrink)

Clinician scientists have gained institutional support in the era of translational research, as the key solution to closing the ‘translational gap’ between biomedical research and medical practice. However, clinician scientists remain an ‘endangered species’ in search of a secure niche, while new grants and training programs attempt to counteract their measurable decline in numbers over the past decades. Our study asks how an occupational space for clinician scientists is currently situated between the politics of translation, professional dynamics, and the specialization (...) of academic disciplines. We interviewed clinician scientists, their adjacent professions—clinicians and biomedical researchers—, and contrast their views with expectations from the discourse on clinician scientists in the biomedical and policy literature. We identify professionalizable work and tasks that relate to, first, being able to speak the two languages of both clinic and research, second, translating patients’ needs and clinical experience for further research, and third, counteracting the trends towards specialization by providing an inclusive point of view. We find that clinician scientists are overburdened with fulfilling a hybrid role of simultaneously being clinicians and scientists. Based on these findings, we suggest a path for the future professional development of clinician scientists towards the role of a translator. (shrink)

Name der Zeitschrift: Neue Zeitschrift für Systematische Theologie und Religionsphilosophie Jahrgang: 61 Heft: 2 Seiten: 165-183.

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 41.1 (2003) 122-123 [Access article in PDF] Andreas Kamp. Philosophiehistorie als Rezeptionsgeschichte. Die Reaktion auf Aristoteles' De Anima-Noetik. Der frühe Hellenismus. Amsterdam: B. R. Grüner, 2001. Pp. viii + 315. Cloth, $82.00. This book is the first installment of an extraordinarily ambitious project. The plan is to investigate the reception of Aristotle's conception of the intellect, set out in De Anima 3.4-5, in (...) the subsequent history of philosophy, from Theophrastus to the present.The current volume deals with the natural starting-point for this project, philosophy in the early Hellenistic period, centering on Theophrastus and his tenure as head of the Peripatos, the school that Aristotle founded.Kamp begins with an engaging, somewhat lengthy introduction, which remains curiously remote from what one might expect it to concentrate on, namely Aristotle's conception of the intellect. Apart from presenting an outline of the reception of Aristotle's philosophical work in general from Theophrastus to Sigmund Freud, the introduction includes only one short paragraph specifically on the topic of the intellect (12). This paragraph, which comes closest to revealing Kamp's reason for focusing, of all things, on Aristotle's discussion of the intellect in De Anima3.4-5, simply makes two unsubstantiated claims. First, Kamp claims that the conception of the intellect, as presented in those chapters, is at the center of the Aristotelian system; and secondly, that this is, of all Aristotelian and perhaps all philosophical theories, the one that received the highest level of attention in the subsequent history of philosophy. The reader might be content to wait and let the second claim be borne out, in the present volume and beyond; but the first claim—concerning the centrality of the intellect, and of De Anima3.4-5, to Aristotle's thought—should at least have received some specification and illustration.The central part of the book, and philosophically by far the most interesting, concerns Theophrastus. Kamp begins with an extensive discussion of the political, social, and economic circumstances of Theophrastus's biography and of the history of the Peripatos. He then offers a reconstruction of Theophrastus's remarks on the nature of the intellect in the fifth book of his Physics. This reconstructive effort is based on a number of fragments [End Page 122] preserved in Themistius's De Anima paraphrase (written at about 350ad) and in Priscianus Lydus's Metaphrasis in Theophrastum (about 530ad). Kamp's discussion of these fragments is well informed, judicious, and illuminating throughout.It may be in order, though, to indicate one misgiving. One of the problems that Theophrastus addresses is that it might appear as if thinking were a matter of the intellect being changed by intelligibles, much as perceiving is, or may appear to be, a matter of sense being changed by sensibles. (If so, the question arises as to what the principle of thought is, the intellect itself or the intelligibles.) Kamp reconstructs the train of thought as follows (124-5).(1) The intellect stands to intelligibles the way sense stands to sensibles (intellect-sense analogy).(2) Sense is changed by sensibles.Therefore, the intellect is changed by intelligibles.Kamp proceeds to suggest (126) that Theophrastus attempted to avoid the conclusion by denying the first premise. According to Kamp, Theophrastus rejected the intellect-sense analogy by drawing attention to significant differences between (the activity of) the intellect and sense perception, one of these being that the intellect (in thinking) is changed only in a special sense, namely inasmuch as it undergoes a transition to activity, energeia. Kamp is right that the notion of a special kind of change that consists in a transition to activity is Aristotelian; it is presented in considerable detail in De Anima2.5 (417b2-16). But it would surely be puzzling if Theophrastus thought that one significant difference between (the activity of) the intellect and sense perception was that the intellect (in thinking) was changed in a special sense (whereas sense perception, to complete the... (shrink)