Brain Organoids in their current state of development are patentable. Future brain organoids may face some challenges in this regard, which I address in this contribution. Brain organoids unproblematically fulfil the general prerequisites of patentability set forth in Art. 3 (1) EU-Directive 98/44/ec (invention, novelty, inventive step and susceptibility of industrial application). Patentability is excluded if an invention makes use of human embryos or constitutes a stage of the human body in the individual phases of its formation and development. Both (...) do not apply to brain organoids, unless ES-cells are used. Art. 6 (1) EU-Directive 98/44/ec excludes patentability for inventions “the commercial exploitation of which would be contrary to ordre public or morality”. While there is no conceivable scenario, in which the commercial application of current brain organoids violates the ordre public, the same is not necessarily true for future brain organoids. Keeping in mind that a development of consciousness-like abilities in future brain organoids cannot be excluded and that an ability for both physical and psychological suffering has been theorized, both of which are aspects of the ordre public, certain applications of future brain organoids may constitute a violation of the ordre public and therefore lead to an exclusion of patentability. (shrink)

Adolescence has been linked to an enhanced tolerance of uncertainty and risky behavior and is possibly connected to an increased response toward rewards. However, previous research has produced inconsistent findings. To investigate whether these findings are due to different reward probabilities used in the experimental design, we extended a monetary incentive delay task by including three different reward probabilities. Using functional magnetic resonance imaging, 25 healthy adolescents and 22 adults were studied during anticipation of rewards in the VS. Differently colored (...) cue stimuli indicated either a monetary or verbal trial and symbolized different reward probabilities, to which the participants were blinded. Results demonstrated faster reaction times for lower reward probabilities in both age groups. Adolescents were slower through all conditions and had less activation on a neural level. Imaging results showed a three-way interaction between age group x condition x reward probability with differences in percent signal change between adolescents and adults for the high reward probabilities while adolescents demonstrated differences for the lowest. Therefore, previous inconsistent findings could be due to different reward probabilities, which makes examining these crucial for a better understanding of adolescent and adult behavior. (shrink)

Originally presented as the author's thesis, Bonn, 1976.

Anstatt die Herkunft von Leibniz' Monadenkonzept in rezeptionsgeschichtlicher Perspektive nachweisen zu wollen, erklärt die vorliegende Studie die offensichtliche Präsenz und Virulenz des Monadenbegriffs im 17. und 18. Jahrhundert selbst zu ihrem Untersuchungsgegenstand.Sie rekonstruiert den frühneuzeitlichen Bildungskanon zum Pythagoreismus, in dem der Monadenbegriff tradiert worden ist, und analysiert vor diesem Hintergrund die monadologischen Philosophien von Gottfried Wilhelm Leibniz, Christian Wolff und Andreas Clavius. An reichem Quellenmaterial zeigt sie, wie die ahistorisch argumentierenden Monadologien von Leibniz und Wolff von deren Zeitgenossen (...) rehistorisiert bzw. "repythagoreisiert", in das Raster des Antike-Moderne-Verhältnisses verortet und auf diese Weise evaluiert worden sind.Ein die Studie beschließender Ausblick fasst die Ergebnisse zusammen und weist selektiv auf die Wege der Monaden in die Moderne hin. (shrink)

What does it mean to be disadvantaged? Is it possible to compare different disadvantages? What should governments do to move their societies in the direction of equality, where equality is to be understood both in distributional and social terms? Linking rigorous analytical philosophical theory with broad empirical studies, including interviews conducted for the purpose of this book, Wolff and de-Shalit show how taking theory and practice together is essential if the theory is to be rich enough to be applied (...) to the real world, and policy systematic enough to have purpose and justification. The book is in three parts. Part 1 presents a pluralist analysis of disadvantage, modifying the capability theory of Sen and Nussbaum to produce the 'genuine opportunity for secure functioning' view. This emphasises risk and insecurity as a central component of disadvantage. Part 2 shows how to identify the least advantaged in society even on a pluralist view. The authors suggest that disadvantage 'clusters' in the sense that some people are disadvantaged in several different respects. Thus identifying the least advantaged is not as problematic as it appears to be. Conversely, a society which has 'declustered disadvantaged' - in the sense that no group lacks secure functioning on a range of functionings - has made considerable progress in the direction of equality. Part 3 explores how to decluster disadvantage, by paying special attention to 'corrosive disadvantages' - those disadvantages which cause further disadvantages - and 'fertile functionings' - those which are likely to secure other functionings. In sum this books presents a refreshing new analysis of disadvantage, and puts forward proposals to help governments improve the lives of the least advantaged in their societies, thereby moving in the direction of equality. (shrink)

It is widely believed that what distinguishes the social cognition of humans from that of other animals is the belief–desire psychology of four–year–old children and adults (so–called theory of mind). We argue here that this is actually the second ontogenetic step in uniquely human social cognition. The first step is one year old children's understanding of persons as intentional agents, which enables skills of cultural learning and shared intentionality. This initial step is ‘the real thing’ in the sense that it (...) enables young children to participate in cultural activities using shared, perspectival symbols with a conventional/normative/reflective dimension—for example, linguistic communication and pretend play—thus inaugurating children's understanding of things mental. Understanding beliefs and participating in collective intentionality at four years of age—enabling the comprehension of such things as money and marriage—results from several years of engagement with other persons in perspective–shifting and reflective discourse containing propositional attitude constructions. (shrink)

_In Defense of Anarchism_ is a 1970 book by the philosopher Robert Paul Wolff, in which the author defends individualist anarchism. He argues that individual autonomy and state authority are mutually exclusive and that, as individual autonomy is inalienable, the moral legitimacy of the state collapses.

Train crashes cause, on average, a handful of deaths each year in the UK. Technologies exist that would save the lives of some of those who die. Yet these technical innovations would cost hundreds of millions of pounds. Should we spend the money? How can we decide how to trade off life against financial cost? Such dilemmas make public policy is a battlefield of values, yet all too often we let technical experts decide the issues for us. Can philosophy help (...) us make better decisions? Ethics and Public Policy: A Philosophical Inquiry is the first book to subject important and controversial areas of public policy to philosophical scrutiny. Jonathan Wolff, a renowned philosopher and veteran of many public committees, such as the Gambling Review Body, introduces and assesses core problems and controversies in public policy from a philosophical standpoint. Each chapter is centred on an important area of public policy where there is considerable moral and political disagreement. Topics discussed include: Can we defend inflicting suffering on animals in scientific experiments for human benefit? What limits to gambling can be achieved through legislation? What assumptions underlie drug policy? Can we justify punishing those who engage in actions that harm only themselves? What is so bad about crime? What is the point of punishment? Other chapters discuss health care, disability, safety and the free market. Throughout the book, fundamental questions for both philosopher and policy maker recur: what are the best methods for connecting philosophy and public policy? Should thinking about public policy be guided by an ‘an ideal world’ or the world we live in now? If there are ‘knock down’ arguments in philosophy why are there none in public policy? Each chapter concludes with ‘Lessons for Philosophy’ making this book not only an ideal introduction for those coming to philosophy, ethics or public policy for the first time, but also a vital resource for anyone grappling with the moral complexity underlying policy debates. (shrink)

Models developed using machine learning are increasingly prevalent in scientific research. At the same time, these models are notoriously opaque. Explainable AI aims to mitigate the impact of opacity by rendering opaque models transparent. More than being just the solution to a problem, however, Explainable AI can also play an invaluable role in scientific exploration. This paper describes how post-hoc analytic techniques from Explainable AI can be used to refine target phenomena in medical science, to identify starting points for future (...) investigations of causal relationships, and to generate possible explanations of target phenomena in cognitive science. In this way, this paper describes how Explainable AI—over and above machine learning itself—contributes to the efficiency and scope of data-driven scientific research. (shrink)

This volume brings together a collection of essays that explore in a new way how unacknowledged moral concerns are integral to debates in the philosophy of mind.The radical suggestion of the book is that we can make sense of the internal dynamics and cultural significance of these debates only when we understand the moral forces that shape them. Drawing inspiration from a variety of traditions including Wittgenstein, Lacan, phenomenology and analytic philosophy, the authors address a wide range of topics including (...) the mind/body-problem, the problem of other minds, subjectivity and objectivity, the debates on mindreading, naturalism, reductive physicalism, representationalism and the ‘E-turn’; Dennett’s heterophenomenology, McDowell’s neo-Kantianism, Wittgenstein’s ‘private language’ considerations and his notion of an ‘attitude towards a soul’; repression, love, conscience, the difficulties of self-understanding, and the methods and aims of philosophy. Through a combination of detailed, immanent criticism and bold constructive work, the authors move the discussion to a new level, beyond humanistic or conservative critiques of naturalism and scientism. (shrink)

If □ is conceived as an operator, i.e., an expression that gives applied to a formula another formula, the expressive power of the language is severely restricted when compared to a language where □ is conceived as a predicate, i.e., an expression that yields a formula if it is applied to a term. This consideration favours the predicate approach. The predicate view, however, is threatened mainly by two problems: Some obvious predicate systems are inconsistent, and possible-worlds semantics for predicates of (...) sentences has not been developed very far. By introducing possible-worlds semantics for the language of arithmetic plus the unary predicate □, we tackle both problems. Given a frame (W, R) consisting of a set W of worlds and a binary relation R on W, we investigate whether we can interpret □ at every world in such a way that □ $\ulcorner A \ulcorner$ holds at a world ᵆ ∊ W if and only if A holds at every world $\upsilon$ ∊ W such that ᵆR $\upsilon$ . The arithmetical vocabulary is interpreted by the standard model at every world. Several 'paradoxes' (like Montague's Theorem, Gödel's Second Incompleteness Theorem, McGee's Theorem on the ω-inconsistency of certain truth theories, etc.) show that many frames, e.g., reflexive frames, do not allow for such an interpretation. We present sufficient and necessary conditions for the existence of a suitable interpretation of □ at any world. Sound and complete semi-formal systems, corresponding to the modal systems K and K4, for the class of all possible-worlds models for predicates and all transitive possible-worlds models are presented. We apply our account also to nonstandard models of arithmetic and other languages than the language of arithmetic. (shrink)

If an agent believes that the probability of E being true is 1/2, should she accept a bet on E at even odds or better? Yes, but only given certain conditions. This paper is about what those conditions are. In particular, we think that there is a condition that has been overlooked so far in the literature. We discovered it in response to a paper by Hitchcock (2004) in which he argues for the 1/3 answer to the Sleeping Beauty problem. (...) Hitchcock argues that this credence follows from calculating her fair betting odds, plus the assumption that Sleeping Beauty’s credences should track her fair betting odds. We will show that this last assumption is false. Sleeping Beauty’s credences should not follow her fair betting odds due to a peculiar feature of her epistemic situation. (shrink)

This volume collects contributions that comprise each view point, and incorporates articles by William Bechtel, Jerry Fodor, Jaegwon Kim, Joėlle Proust, and ...

Ontic structural realists hold that structure is all there is, or at least all there is fundamentally. This thesis has proved to be puzzling: What exactly does it say about the relationship between objects and structures? In this article, I look at different ways of articulating ontic structural realism in terms of the relation between structures and objects. I show that objects cannot be reduced to structure, and argue that ontological dependence cannot be used to establish strong forms of structural (...) realism. At the end, I show how a weaker, but controversial, form of structural realism can be articulated on the basis of ontological dependence. (shrink)

Over the past years, a number of probabilistic measures of coherence have been proposed. As shown in the paper, however, many of them do not conform to the intuitition that equivalent testimonies are highly coherent, regardless of their prior probability.

This paper reconsiders some themes and arguments from my earlier paper “Fairness, Respect and the Egalitarian Ethos.” That work is often considered to be part of a cluster of papers attacking “luck egalitarianism” on the grounds that insisting on luck egalitarianism's standards of fairness undermines relations of mutual respect among citizens. While this is an accurate reading, the earlier paper did not make its motivations clear, and the current paper attempts to explain the reasons that led me to write the (...) earlier paper, assesses the force of its arguments, and locates it in respect to work of Richard Arneson and Elizabeth Anderson. The paper concludes by bringing out what now appears to be the main message of the earlier paper: that the attempt to implement an “ideal” theory of equality can harm the very people that the theory is designed to help. (shrink)

In this chapter we will deal with “mechanizing” induction, i.e. with ways in which theoretical computer science approaches inductive generalization. In the field of Machine Learning, algorithms for induction are developed. Depending on the form of the available data, the nature of these algorithms may be very different. Some of them combine geometric and statistical ideas, while others use classical reasoning based on logical formalism. However, we are not so much interested in the algorithms themselves, but more on the philosophical (...) and theoretical foundations they share. Thus in the first of two parts, we will examine different approaches and inductive assumptions in two particular learning settings. While many machine learning algorithms work well on a lot of tasks, the interpretation of the learned hypothesis is often difficult. Thus, while e.g. an algorithm surprisingly is able to determine the gender of the author of a given text with about 80 percent accuracy [Argamon and Shimoni, 2003], for a human it takes some extra effort to understand on the basis of which criteria the algorithm is able to do so. With that respect the advantage of approaches using logic are obvious: If the output hypothesis is a formula of predicate logic, it is easy to interpret. However, if decision trees or algorithms from the area of inductive logic programming are based purely on classical logic, they suffer from the fact that most universal statements do not hold for exceptional cases, and classical logic does not offer any convenient way of representing statements which are meant to hold in the “normal case”. Thus, in the second part we will focus on approaches for Nonmonotonic Reasoning that try to handle this problem. Both Machine Learning and Nonmonotonic Reasoning have been anticipated partially by work in philosophy of science and philosophical logic. At the same time, recent developments in theoretical computer science are expected to trig- ger further progress in philosophical theories of inference, confirmation, theory revision, learning, and the semantic and pragmatics of conditionals. We hope this survey will contribute to this kind of progress by building bridges between computational, logical, and philosophical accounts of induction. (shrink)

The fall of the Berlin Wall had enormous symbolic resonance, marking the collapse of Marxist politics and economics. Indeed, Marxist regimes have failed miserably, and with them, it seems, all reason to take the writings of Karl Marx seriously. Jonathan Wolff argues that if we detach Marx the critic of current society from Marx the prophet of some never-to-be-realized worker's paradise, he remains the most impressive critic we have of liberal, capitalist, bourgeois society. The author shows how Marx's main (...) ideas still shed light on wider concerns about culture and society and he guides the reader through Marx's notoriously difficult writings. Wolff also argues that the value of a great thinker does not depend on his or her views being true, but on other features such as originality, insight, and systematic vision. From this perspective, Marx still richly deserves to be read. Why Read Marx Today? reinstates Marx as an important critic of current society, and not just a figure of historical interest. (shrink)

This volume gives an overview of the rising field of Experimental Ethics. It is organized into five main parts: PART I – Introduction: An Experimental Philosophy of Ethics? // PART II – Applied Experimental Ethics: Case studies // PART III – On Methodology // PART IV – Critical Reflections // PART V – Future Perspectives. Among the contributors: Walter Sinnott-Armstrong, Eric Schwitzgebel, Ezio di Nucci, Jacob Rosenthal, and Fernando Aguiar.

Solidarity is one of the central concepts in social theory and has gained much attention due to the multiple challenges that the EU has been facing the last decade and due to the most recent COVID-19 pandemic. Although the debate on the nature and conditions of solidarity has been revitalized, there remains a large variety in how to conceptualize solidarity. In contrast to other approaches, we do not conceive solidarity as normative concept, but as descriptive–analytical one. Therefore, we provide a (...) theory-based definition that is prone to capture the empirical dimensions of solidarity. Accounting for the dynamic and interactive character of solidarity as subject to permanent societal and political renegotiation, we conceptualize solidarity from a discourse perspective and follow a multilevel design breaking down the understandings of solidarity on different levels. This approach contributes to the research of solidarity that is interested to capturing the ‘real world’ dimensions of solidarity. (shrink)

The difficulties with formalizing the intensional notions necessity, knowability and omniscience, and rational belief are well-known. If these notions are formalized as predicates applying to (codes of) sentences, then from apparently weak and uncontroversial logical principles governing these notions, outright contradictions can be derived. Tense logic is one of the best understood and most extensively developed branches of intensional logic. In tense logic, the temporal notions future and past are formalized as sentential operators rather than as predicates. The question therefore (...) arises whether the notions that are investigated in tense logic can be consistently formalized as predicates. In this paper it is shown that the answer to this question is negative. The logical treatment of the notions of future and past as predicates gives rise to paradoxes due the specific interplay between both notions. For this reason, the tense paradoxes that will be presented are not identical to the paradoxes referred to above. (shrink)

Utilitarianism has a curious history. Its most celebrated founders—Jeremy Bentham and John Stuart Mill—were radical progressives, straddling the worlds of academic philosophy, political science, economic theory and practical affairs. They made innumerable recommendations for legal, social, political and economic reform, often (especially in Bentham’s case) described in fine detail. Some of these recommendations were followed, sooner or later, and many of their radical ideas have become close to articles of faith of western liberalism. Furthermore many of these recommendations were made (...) expressly to improve the condition of the deprived, or of oppressed groups. Yet the moral theory which inspired this reforming zeal is, at least officially, utilitarianism, and when we teach this theory to our students we feel it our duty to point out the horrors that could be justified by any theory which assesses the moral quality of actions in terms of the maximization of good consequences over bad. No consequence is so bad that it cannot, in principle, be outweighed by a large aggregation of smaller goods. Hence there are circumstances in which utilitarianism can require slavery, the punishment of the innocent, and redistribution of resources from the poor to the rich, or from the disabled and the sick to the able bodied and healthy. Indeed, in the right circumstances, it can justify pretty much anything you can think of. For all their intelligence and imagination neither Bentham nor Mill seemed to recognise or discuss these catastrophic possibilities. (shrink)

“This volume’s twenty-one essays present a spectrum of contemporary understandings and interpretations of the philosophy of Immanuel Kant. In the three general areas of Kant’s Critique of Pure Reason, his ethical theory, and his aesthetics, various particular aspects of Kant’s philosophy are examined in depth. Connecting papers discuss his concept of synthetic and analytic and debate the meaning of the categorical imperative. A wide range of post-war scholarship is represented: all of the papers have been written since 1945, and three (...) appear in this volume for the first time. No philosopher has had a greater influence on contemporary thought than Kant; his influence and the place of his ideas in contemporary philosophical argument are evidenced and illuminated in these essays.”- Publisher. (shrink)

The discussion of the adequacy of Karl Marx''s definition of exploitation has paid insufficient attention to a prior question: what is a definition? Once we understand Marx as offering a reference-fixing definition in a model we will realise that it is resistant to certain objections. A more general analysis of exploitation is offered here and it is suggested that Marx''s own definition is a particular instance of the general analysis which makes a number of controversial moral assumptions.

The Swiss photographer and filmmaker Rudolph Burckhardt came to New York City in 1935 and experienced the awe that many first-time visitors to the city share. The grandeur, the energy, the vitality, the sheer movement of this American metropolis all drew Burckhardt in, and he made New York his home for the rest of his life. Equally inflecting his career as a photographer and filmmaker, the city and its vibrant cultural life became Burckhardt's muse. Rudy Burckhardt—New York Moments is a (...) rare collection of his photographs from the 1940s and 1950s. It includes not only street scenes and details of city life—“The tremendous difference in scale between the soaring buildings and the people in the street astonished me,” he wrote—but also the portraits he made of the New York School painters, most notably Jackson Pollock, Mark Rothko, and Willem de Kooning. As a photographer for ArtNews in the 1950s, Burckhardt had an insider’s view of the burgeoning art scene. But he also recognized the limits of photography—“a photograph, when it gets printed and comes out a picture, becomes like a fact, you know”—and turned his hand to filmmaking. For the rest of his career, photography and film would work together to capture his unique vision. Including photographs, film stills, and interpretive essays, Rudy Burckhardt accompanies an exhibition of Burckhardt's work at the Kunstmuseum Basel in Basel, Switzerland, and is a fitting tribute to the Swiss photographer who most poignantly captured the energy of mid-century New York. (shrink)

The literature of modernity, describing the fleeting, anonymous, ephemeral encounters of life in the metropolis, mainly accounts for the experiences of men. It ignores the concomitant separation of public and private spheres from the mid-nineteenth century, and the increasing segregation of the sexes around that separation. The influential writings of Baudelaire, Simmel, Benjamin and, more recently, Richard Sennett and Marshall Berman, by equating the modern with the public, thus fail to describe women's experience of modernity. The central figure of the (...) flâneur in the literature of modernity can only be male. What is required, therefore, is a feminist sociology of modernity to supplement these texts. (shrink)

In this extended prose poem—a text that reads as much as a work of art as important scholarship—Kurt H. Wolff has created a work of phenomenology that goes far beyond the typical methods of empirical social science to embrace field work as an extraordinary openness to being. Including personal letters to Wolff from Hannah Arendt and Hermann Bloch, the book portrays a fertile mind's reckoning with pre-phenomenal being in a way that dances between the realms of intellectual consideration (...) and the surrender of will to the intoxication of lived experience. (shrink)

The paper describes a project in which the thesis of the social determinants of health is used in order to help identify groups that will be among the least advantaged members of society, when disadvantage is understood in terms of lack of genuine opportunity for secure functioning. The analysis is derived from the author's work with Avner de-Shalit in Disadvantage (Oxford University Press, 2007).

The chapter describes the sharing economy in Germany as a heterogeneous dynamic, combining local trends and histories with economic forms drawing on experiences mainly from across Europe and North America. Increasingly taken into account by policymakers in the regulation of markets and the redesign of innovation governance frameworks, “sharing” as a complex nexus linking the exercise of citizenship to sustainable consumption and informational self-determination in digital societies will continue to drive and frame the creation of value chains. Of particular interest (...) are linkages between sharing economies and the traditions of cooperativism, currently experiencing a renaissance. The latter is key because it shapes the context in which sharing economy initiatives exist and expand—an opening of definitions and narrative of innovation, of value, and of collaborative agency and cooperative management. (shrink)

It often appears that the most appropriate form of addressing disadvantage related to disability is through policies that can be called “status enhancements”: changes to the social, cultural and material environment so that the difficulties experienced by those with impairments are reduced, even eradicated. However, status enhancements can also have their limitations. This paper compares the relative merits of policies of status enhancement and “personal enhancement”: changes to the disabled person. It then takes up the question of how to assess (...) the priority of the claims of disabled people in the face of scarcity of resources for which there can be many competing social claims, arguing for the theory of “declustering disadvantage”. (shrink)

In this paper we describe and interpret the formal machinery of abstraction processes in which the domain of abstracta is a subset of the domain of objects from which is abstracted.

This article examines Kant′s use of the expression “fact of reason” by giving an analysis of the pseudo-mathematical method which Kant employs in the first part of the Critique of Practical Reason. It turns out that Kant′s use of this expression has nothing to do with appealing to a certain fact as being an obvious, self-evident truth. There is no need for such an appeal since the “Fundamental Law of Pure Practical Reason” is a “practical postulate” which, like a postulate (...) in geometry, is unquestionably certain. In order to realize its validity it is sufficient to know what a practical law is and on what its validity depends. The fundamental law of pure practical reason needs, in Kant′s view, a “deduction” since it is a synthetic principle a priori. But its deduction cannot be a proof since postulates neither can nor need be proved. It has to be a justification which guarantees that the use of pure reason in giving practical laws is not “transcendent”, but “immanent”. This justification has, unlike Kant′s deduction of the “Postulates of Empirical Thinking”, the systematic form of a “defence” which invalidates possible objections by showing that they themselves necessarily rest on a transcendent use of reason. (shrink)