Background: It has been reported that type 2 diabetes is associated with olfactory identification impairments and cognitive decline. However, the relationship between OI impairments and cognitive decline is largely unknown in T2DM patients.Methods: Sixty-eight T2DM patients and 68 healthy controls underwent 3D-T1 MRI scans, olfactory and cognitive assessments. The cortical thickness of olfaction-related brain regions, olfactory and cognitive scores were compared between groups. Correlation analyses were carried out among cognition, olfaction, and cortical thickness of olfaction-related brain regions.Results: First, the cognitive (...) and olfactory test scores of T2DM patients were lower than healthy subjects. Second, higher olfactory scores were associated with increased cortical thickness in the left parahippocampal gyrus and bilateral insula in T2DM. Third, higher olfactory scores were associated with higher cognitive performance in T2DM. Fourth, some cognitive performances were related to cortical thickness in the left parahippocampal gyrus and left insula in T2DM.Conclusion: These findings indicated that olfactory dysfunction may be useful for future applications that attempt to predict cognitive decline or develop tailored therapies in T2DM patients. (shrink)

What, if anything, makes death bad for the deceased themselves? Deprivationists hold that death is bad for the deceased iff it deprives them of intrinsic goods they would have enjoyed had they lived longer. This view faces the problem that birth too seems to deprive one of goods one would have enjoyed had one been born earlier, so that it too should be bad for one. There are two main approaches to the problem. In this paper, I explore the second (...) approach, by Anthony Brueckner and John Martin Fischer, and suggest that it can be developed so as to meet deprivationists’ needs. On the resulting view, metaphysical differences between the future and the past give rise to a corresponding axiological difference in the intrinsic value of future and past experiences. As experiences move into the past, they lose their intrinsic value for the person. (shrink)

本书运用本体分割的道德方法,对人进行本体论的析分,从历史生成的角度对伦理的政治过程提出了全新的解释。.

本书把最新反映邓小平哲学思想特色的论述分为:解放思想,实事求是,照辩证法办事,改革是解放和发展生产力的必由之路,面向世界,吸收人类文明成果等10部分加以编辑。.

Elsewhere I have suggested that the B-theory includes a notion of passage, by virtue of including succession. Here, I provide further support for that claim by showing that uncontroversial elements of the B-theory straightforwardly ground a veridical sense of passage. First, I argue that the B-theory predicts that subjects of experience have a sense of passivity with respect to time that they do not have with respect to space, which they are right to have, even according to the B-theory. I (...) then ask what else might be involved in our experience of time as passing that is not yet vindicated by the B-theoretic conception. I examine a recent B-theoretic explanation of our ‘illusory’ sense of passage, by Robin Le Poidevin, and argue that it explains away too much: our perception of succession poses no more of a problem on the B-theory than it does on other theories of time. Finally, I respond to an objection by Oreste Fiocco that a causal account of our sense of passage cannot succeed, because it leaves out the ‘phenomenological novelty’ of each moment. (shrink)

Usually, the B-theory of time is taken to involve the claim that time does not, in reality, pass; after all, on the B-theory, nothing really becomes present and then more and more past, times do not come into existence successively, and which facts obtain does not change. For this reason, many B-theorists have recently tried to explain away one or more aspect(s) of experience that they and their opponents take to constitute an experience of time as passing. In this paper, (...) I examine three prominent proposals of this kind and argue that, though intriguing, the proposals undermine, to some extent, the assumption that there is an element of experience that B-theorists need to take to be illusory. (shrink)

This essay argues that individual-oriented informed consent is inadequate to protect human research subjects in mainland China. The practice of family-oriented decision-making is better suited to guide moral research conduct. The family’s role in medical decision-making originates from the mutual benevolence that exists among family members, and is in accordance with family harmony, which is the aim of Confucian society. I argue that the practice of informed consent for medical research on human subjects ought to remain family-oriented in mainland China. (...) This essay explores the main features of this model of informed consent and demonstrates the proper authority of the family. The family’s participation in decision-making as a whole does not negate or deny the importance of the individual who is the subject of the choice, but rather acts more fully to protect research subjects. (shrink)

This article is a response to Clifford Williams’s claim that the debate between A- and B theories of time is misconceived because these theories do not differ. I provide some missing support for Williams’s claim that the B-theory includes transition, by arguing that representative B-theoretic explanations for why we experience time as passing (even though it does not) are inherently unstable. I then argue that, contra Williams, it does not follow that there is nothing at stake in the A- versus (...) B debate. (shrink)

Some naturalists feel an affinity with some religions, or with a particular religion. They may have previously belonged to it, and/or been raised in it, and/or be close to people who belong to it, and/or simply feel attracted to its practices, texts and traditions. This raises the question of whether and to what extent a naturalist can lead the life of a religious believer. The sparse literature on this topic focuses on religious fictionalism. I also frame the debate in these (...) terms. I ask what religious fictionalism might amount to, reject some possible versions of it and endorse a different one. I then examine the existing proposals, by Robin Le Poidevin, Peter Lipton, Andrew Eshleman and Howard Wettstein, and show that even on my version of religious fictionalism, much of what has been described by these authors is still possible. (shrink)

To cope with the water deficit resulting from saline environment, plant cells accumulate three kinds of osmotica: salts, small organic solutes and hydrophillic, glycine-rich proteins. Salts such as NaCl are cheap and available but has ion toxicity in high concentrations. Small organic solutes are assistant osmotica, their main function is to protect cytoplasmic enzymes from ionic toxicity and maintain the integrity of cellular membranes. Hydrophillic, glycine-rich proteins are the most effective osmotica, they have some characteristics to avoid crystallization even in (...) high concentration, but because they are expensive they are not as commonly used as salts or organic solutes. In addition there is the question of whether the genetic information for growth in saline environment is present in all kinds of plants, both halophytes and nonhalophytes. (shrink)

From the viewpoint of an evolutionary biologist, carcinogenesis should be looked upon as a protective mechanism against destruction of DNA. Because genes expressed in embryonic cells are covered and protected by heterochromatinization, they are the most appropriate ‘alternate genes’ compared to genes that are expressed already in somatic cells. When DNA-damage occurs, the embryonic genes can be activated. Some somatic cells exhibit some features of embryonic cells.

In order to establish his "school of principle" system of thought, which was founded on objective idealism, Zhu Xi proposed a theory of "investigating things and exhausting principles" [gewu qiongli]. This became the epistemological foundation for his system of thought. This epistemology formed an organic whole with his world view. On the one hand, his "theory-of-investigating-things" epistemology opened up pathways for his system of objective idealism; on the other hand, his "school-of-principle" system formed the theoretical foundation for his epistemology of (...) "investigating things" and gave this epistemology its obviously metaphysical characteristics. (shrink)

In this paper I revisit a dispute between Mikel Burley and Robin Le Poidevin about whether or not the B-theory of time can give its adherents any reason to be less afraid of death. In ‘Should a B-theoretic atheist fear death?’, Burley argues that even on Le Poidevin’s understanding of the B-theory, atheists shouldn’t be comforted. His reason is that the prevalent B-theoretic account of our attitudes towards the past and future precludes treating our fear of death as unwarranted. I (...) examine his argument and provide a tentative defense of Le Poidevin. I claim that while Burley rightly spots a tension with a non-revisionary approach to our ordinary emotional life, he doesn’t isolate the source of that tension. The real question is how to understand Le Poidevin’s idea that on the B-theory, we and our lives are ‘eternally real’. I then suggest that there is a view of time that does justice to Le Poidevin’s remarks, albeit a strange one. The view takes temporal relations to be quasi-spatial and temporal entities to exist in a totum simul. (shrink)

Literary ontology is essentially a phenomenological issue rather than one of epistemology, sociology, or psychology. It is a theory of the phenomenological essence intuited from a sense of beauty, based on the phenomenological ontology of beauty, which puts into brackets the sociohistorical premises and material conditions of aesthetic phenomena. Beauty is the objectified emotion. This is the phenomenological definition of the essence of beauty, which manifests itself on three levels, namely emotion qua selfconsciousness, sense of beauty qua emotion, and sentiment (...) qua sense of beauty. Art on the other hand is the objectification of emotion whose most general and closest manner to humanity is literature and poetry. Poetry is the origin of language and the linguistic essence is a metaphor. Language as the house of being is both thinking and poetry. Literature expresses the essence of art in the most direct way and, in traditional Chinese aesthetic terminology, literature is the language of emotion conveyed by the writer based on his own emotion towards the language of scene. (shrink)

This essay reveals five points in which Heidegger misreads Hegel in “Hegel’s Concept of Experience”: (1) By forcedly introducing the concept of “will”, he interprets Hegel’s phenomenology of spirit into Metaphysics of Presence; (2) interprets concepts such as “statement” and “the road of skeptics” as the process of phenomenological reduction; (3) reduces Hegel’s Sein to Seiende; (4) replaces “Contradiction” with “Ambiguity” so the active Dialectics become passive; (5) exaggerates conscious experience and puts it into a real ontology, regardless of the (...) significance of Logic and Encyclopedia of Philosophy . By an analysis of this misreading we can find the internal connection between Heidegger’s thought and that of his philosophical forerunner, Hegel. (shrink)

This essay reveals five points in which Heidegger misreads Hegel in "Hegel's Concept of Experience": (1) By forcedly introducing the concept of "will", he interprets Hegel's phenomenology of spirit into Metaphysics of Presence; (2) interprets concepts such as "statement" and "the road of skeptics" as the process of phenomenological reduction; (3) reduces Hegel's Sein to Seiende; (4) replaces "Contradiction" with "Ambiguity" so the active Dialectics become passive; (5) exaggerates conscious experience and puts it into a real ontology, regardless of the (...) significance of Logic and Encyclopedia of Philosophy. By an analysis of this misreading we can find the internal connection between Heidegger's thought and that of his philosophical forerunner, Hegel. /// 在"黑格尔的经验概念"一文中，海德格尔对黑格尔有五个方面的有意误读: (1)用强行引入的"意志"概念将黑格尔的精神现象学解释为在场的形而上学;(2) 将黑格尔的"陈述"、"怀疑之路"等概念解释为现象学还原的程序(3) 将黑格 尔的"存在(Sein) "贬为仅仅是指"存在者(4) 将"矛盾"置换为"模棱两 可使黑格尔的辩证运动从主动变为被动(5) 将意识的经验夸大为真正的本体 论，无视《逻辑学》和《哲学百科全书》的意义。通过分析这样的误i卖，有助于我 们了解海德格尔和黑格尔思想之间的内在联系。. (shrink)

Temporal ontology is the part of ontology involving the rival positions of presentism, eternalism, and the growing block theory. While this much is clear, it’s surprisingly difficult to elucidate the substance of the disagreement between presentists and eternalists. Certain events happened that are not happening now; what is it to disagree about whether these events exist? In spite of widespread suspicion concerning the status and methods of analytic metaphysics, skeptics’ doubts about this debate have not generally been heeded, neither by (...) metaphysicians, nor by philosophers of physics. This paper revisits the question in the light of prominent elucidation attempts from both camps. The upshot is that skeptics were right to be puzzled. The paper then explores a possible re-interpretation of positions in temporal ontology that links it to normative views about how we should live as temporal beings. (shrink)

With a previous paper (Niu & Wang, 1995), a general, hypothetical outline of the mechanism of carcinogenesis was proposed. With reference to the fact of starvation-induced hypermutation in micro-organisms, we propose that the hypoxia commonly seen in the cells at the centre of solid tumours might also result in hypermutation, and then p53-dependent programmed cell death. Like the apparently adaptive mutations in micro-organisms, only those genes (e.g. p53) that enable the cells to escape from apoptosis may be selected.

Division of labour is a marked feature of multicellular organisms. Margulis proposed that the ancestors of metazoans had only one microtubule organizing center (MTOC), so they could not move and divide simultaneously. Selection for simultaneous movement and cell division had driven the division of labour between cells. However, no evidence or explanation for this assumption was provided. Why could the unicellular ancetors not have multiple MTOCs? The gain and loss of three possible strategies are discussed. It was found that the (...) advantage of one or two MTOC per cell is environment-dependent. Unicellular organisms with only one MTOC per cell are favored only in resource-limited environments without strong predatory pressure. If division of labour occurring in a bicellular organism just makes simultaneous movement and cell division possible, the possibility of its fixation by natural selection is very low because a somatic cell performing the function of an MTOC is obviously wasting resources. Evolutionary biologists should search for other selective forces for division of labour in cells. (shrink)

Does time seem to pass, even though it doesn’t, really? Many philosophers think the answer is ‘Yes’—at least when ‘time’s passing’ is understood in a particular way. They take time’s passing to be a process by which each time in turn acquires a special status, such as the status of being the only time that exists, or being the only time that is present. This chapter suggests that, on the contrary, all we perceive is temporal succession, one thing after another, (...) a notion to which modern physics is not inhospitable. The contents of perception are best described in terms of ‘before’ and ‘after’, rather than ‘past’, ‘present, and ‘future’. (shrink)

本书以中国文艺审美的民族心理特征与哲学思维向度为基点, 对中国古典文艺美学的"表现"范型进行"扫描", 在"表现"层面对中国古典文艺美学进行新的探索, 彰显了中国古典文艺美学与西方古典文艺美学不同的美学趣味, 并进而探索了中国文艺理论古为今用个有效途径.

I offer an interpretation and a partial defense of Kit Fine's ‘Argument from Passage’, which is situated within his reconstruction of McTaggart's paradox. Fine argues that existing A-theoretic approaches to passage are no more dynamic, i.e. capture passage no better, than the B-theory. I argue that this comparative claim is correct. Our intuitive picture of passage, which inclines us towards A-theories, suggests more than coherent A-theories can deliver. In Finean terms, the picture requires not only Realism about tensed facts, but (...) also Neutrality, i.e. the tensed facts not being ‘oriented towards’ one privileged time. However unlike Fine, and unlike others who advance McTaggartian arguments, I take McTaggart's paradox to indicate neither the need for a more dynamic theory of passage nor that time does not pass. A more dynamic theory is not to be had: Fine's ‘non-standard realism’ amounts to no more than a conceptual gesture. But instead of concluding that time does not pass, we should conclude that theories of passage cannot deliver the dynamicity of our intuitive picture. For this reason, a B-theoretic account of passage that simply identifies passage with the succession of times is a serious contender. (shrink)

This article is an evaluation of Le Poidevin’s use of Carnap ’s stance on ontology within the philosophy of religion. Le Poidevin claims that 1) theists need to take God to be a putative entity within space-time in order for their claim that God exists to be meaningful, and that 2) instrumentalism about theology is viable. I argue that although Le Poidevin’s response to Carnap ’s argument is no less problematic than that argument itself, his position is in fact thoroughly (...) un-Carnapian. The upshot is that his discussion provides some support to atheism, but none to either of his two official conclusions. (shrink)

Present-bias is the preference, all else being equal, for positive events to be located in the present rather than the non-present, and for negative events to be located in the non-present rather than the present. Very little attention has been given to present-bias in the contemporary literature on time biases. This may be because it is often assumed that present-bias is not a distinctive psychological kind; that what explains people’s being present-biased is just what explains them displaying various other time-biases. (...) According to this view, there is no need to investigate present-bias independently of investigating these other biases, since present-bias is really just a manifestation of these other biases. We call this the manifestation thesis. We take up the question of whether the manifestation thesis is true, and argue that it is not. Thus, by failing to investigate present-bias in its own right we are failing fully to understand the spectrum of ways in which people display time biases. In turn, we suggest, this may have implications for the ways we evaluate whether present-bias is rationally permissible. (shrink)

Writing, or calligraphy, in China is strongly influenced by ancient techniques of making art. Chinese characters have evolved from the patterns of bronze drawings, and China’s earliest hieroglyphs usually retain the traces of their origin in paintings. These paintings usually recorded daily life, and the related Chinese characters have evolved from these with general, simplified and abstract features. The composition that makes Chinese characters is a manifestation of ancient Chinese philosophy, of which Confucianism, Taoism and Buddhism are the three key (...) strands. They have affected Chinese culture and aesthetics in all dynasties. Chinese philosophy emphasizes the integration of individuals in their surrounding environment. The art of ancient China consequently combines skills that relate to the artificial, or constructed, and to natural patterns. Chinese characters make a perfect example of this. The article/presentation will outline the research that I have so far undertaken on the relation between Chinese calligraphy and architectural space, between writing and constructing environments. It will also present some experimental design research that aims at developing from the above-mentioned basic research new architectural typologies that are contemporary, resonant and sensitive to the Chinese context. (shrink)

The response of consumers to a firm’s ethical behavior and the underlying factors influencing/forming each consumer’s response outcome is analyzed in this article based on information obtained through interviews. The results indicate that, in the Chinese context, the responding outcome can be boiled down to five types, namely, resistance, questioning, indifference, praise, and support. Additionally, consumers’ responses were mainly influenced by the specific consumer’s ethical consciousness, ethical cognitive effort, perception of ethical justice, motivation judgment, institutional rationality, and corporate social responsibility–corporate (...) ability (CSR–CA) belief. Based on these results, a generalized framework of consumer’s ethical responses is developed which provides a number of insightful suggestions upon how to motivate a consumer’s support of a firm’s ethical behavior and to transfer this kind of support into truly positive purchasing behavior. (shrink)

This chapter discusses some aspects of the relation between temporal experience and the A versus B debate. To begin with, I provide an overview of the A versus B debate and, following Baron et al. (2015), distinguish between two B-theoretic responses to the A- theoretic argument from experience, veridicalism and illusionism. I then argue for veridicalism over illusionism, by examining our (putative) experiences as of presentness and as of time passing. I close with some remarks on the relation between veridicalism (...) and a deflationary view of the A versus B debate. I suggest that the deflationary view can provide further support for veridicalism. (shrink)

The God of Western religion is said to be eternal. But what does that mean? Is God somehow beyond time, living a life that does not involve one thing after another? Or is God's relationship to time much more like ours, so that God's eternality just consists in there being no time at which God doesn't exist? Even for non-believers, these issues have interesting implications for the relation between historical and scientific findings on the one hand, and religion on the (...) other. This Element introduces the reader to the requisite metaphysical background, and then examines reasons for and against thinking of God as timeless. (shrink)

Emotions are believed to converge both through emotional mimicry and social appraisal. The present study compared contagion of anger and happiness. In Experiment 1, participants viewed dynamic angry and happy faces, with facial electromyography recorded from the zygomaticus major and corrugator supercilii as emotional mimicry. Self-reported emotional experiences were analyzed as emotional contagion. Experiment 2 manipulated social appraisal as the gaze of expression toward the target. The results showed that there was emotional contagion for angry and happy expressions both in (...) Experiment 1 and Experiment 2. Experiment 1 indicated an overt mimicry pattern for happy faces, but not for angry faces. Experiment 2 found an influence of social appraisal on angry contagion but not on happy diffusion. The two experiments suggest that the underlying processes of emotional mimicry and social appraisal are differentially relevant for different emotional contagion, with happiness processing following a mimicry-based path to emotional contagion, and anger processing requiring social appraisal. (shrink)

Comrade Hu Qili, on behalf of the Central Secretariat, has delivered a speech of congratulations at the Fourth Congress of the National Writers' Association. This speech is very important. In it, Comrade Hu Qili stated: "As regards the freedom of [artistic] creation, the Party and state should provide the necessary conditions [for it] and create the necessary environment and atmosphere. At the same time, the writers' own thoughts and feelings and their creative activities as a whole should be in step (...) with the environment of freedom provided by the Party and state." Demands are made on both sides. On the one hand, the Party and state should create the requisite conditions, environment, and atmosphere for literary creation. The civil liberties stipulated in the Constitution include the freedom of creation. For writers who are Party members, the rights of Party members, stipulated by the Party constitution and by the Party's criteria for political life, also include the right of freedom of creation. Many problems still exist in this respect; situations still exist wherein no active measures are being taken to create the conditions, environment, and atmosphere for writers to fully enjoy the freedom of creation due to them. [The authorities] in some localities even obstruct or willfully interfere with the realization of this freedom, or they suppress democracy, resort to persecution and retaliation, or employ crude and simplistic means to deal with writers and with artistic creation—a meticulous form of mental labor that has its own special regularities. The thorough solution of problems of this sort still requires great efforts on our part. On the other hand, Comrade Hu Qili also said in his congratulatory speech that the writers' own thoughts and feelings and their creative activities as a whole should be in step with the environment of freedom provided the Party and state. That is to say, they must remain in step with the Constitution, and where Party-member writers are concerned, they should remain in step with the Party constitution, and they should ensure the implementation of relevant stipulations in the Constitution and Party constitution. Many efforts must be made, whether by Party committees and governments at various levels or by the writers, to promote the healthy development and continued flourishing of socialist literature and art. Hence, the two sentences in Comrade Qili's congratulatory speech address the matter very comprehensively. (shrink)

In his recent book ‘Experiencing time’, Simon Prosser discusses a wide variety of topics relating to temporal experience, in a way that is accessible both to those steeped in the philosophy of mind, and to those more familiar with the philosophy of time. He forcefully argues for the conclusion that the B-theorist of time can account for the temporal appearances. In this article, I offer a chapter by chapter response.

This paper investigates the connection between temporal attitudes (attitudes characterised by a concern (or lack thereof) about future and past events), beliefs about temporal ontology (beliefs about the existence of future and past events) and temporal preferences (preferences regarding where in time events are located). Our aim is to probe the connection between these preferences, attitudes, and beliefs, in order to better evaluate the normative status of these preferences. We investigate the hypothesis that there is a three-way association between (a) (...) being present-biased (that is, preferring that positive events are located in the present, and negative events are located in the non-present), (b) believing that past and future events do not exist and (c) tending to have present-focused rather than non-present-focused temporal attitudes. We find no such association. This suggests that insofar as temporal preferences and temporal attitudes are connected to the ways we represent time, they are not connected to the ways we represent temporal ontology; rather, they are more likely connected to the ways we represent relative movement in, or of, time. This has important consequences for, first, explaining why we exhibit these preferences and, second, for their normative evaluation. (shrink)

In this paper, I try to make sense of the growing block view using Kit Fine’s three-fold classification of A-theoretic views of time. I begin by motivating the endeavor of making sense of the growing block view by examining John Earman’s project in ‘Reassessing the prospects for a growing block model of the universe’. Next, I review Fine’s reconstruction of McTaggart’s argument and its accompanying three-fold classification of A-theoretic views. I then consider three interpretations of Earman’s growing block model: the (...) hybrid growing block, the purely tensed growing block, and Michael Tooley’s growing block. I argue for three claims. First, Finean ‘standard’ versions of these views are less congenial to the growing blocker than ‘non-standard’ ones. Second, the hybrid view is problematic on either version. And third, ‘non-standard’ versions are not fully intelligible. I provide further support for the first and third of these claims and explain why I take them to support a minimal account of passage as succession, which undercuts some of the motivation for Earman’s project. Lastly, I answer three objections. (shrink)

In its three decades of development, many constructs of cause-related marketing have been tested from different perspectives and in varied contexts. However, there has not yet been an integrated empirical study. Reviewing 162 studies from 117 articles, we constructed a framework of meta-analysis and identified 20 constructs. Among these, 13 are antecedents that can be grouped into three components: consumer-related traits, execution-related factors, and product-related traits, while three mediators and four consequences are used to measure the effectiveness of cause-related marketing. (...) Moreover, we examined 857 relationships among the constructs. The results showed that consumer-related traits, execution-related factors, and product-related traits all influence the effectiveness of cause-related marketing to varying degrees. Furthermore, we analyzed the effects of six moderators and found that cause-related marketing would be more effective when the brand is familiar, the product is utilitarian, the donation magnitude is large, and the cause is less familiar. However, neither cultural orientation nor cause type significantly influences the effectiveness of cause-related marketing. Finally, the interactions between these moderators and execution-related antecedents provide contributions and implications for cause-related marketing. (shrink)

本书内容包括:马一浮其人其学、“六艺一心论”的思想体系及其论证、“六艺一心论”之评价、马一浮与熊十力的六艺论之比较等。.

本书包括《南询录》校注记、《南询录》校注、记录邓豁渠生平的文献资料、研究邓豁渠的两篇论文这四个部分的内容。.