In this study, Brian Carrier provides a comprehensive analysis of the role that seismic language plays within the Matthean Gospel narrative. After reconstructing what connotations seismic language likely carried in Matthew's cultural context, the author utilizes an historically informed author-oriented narrative criticism that is complemented with redaction criticism to analyze the relationships that Matthew's seismic references display with regards to each other and to the overall narrative. This analysis leads to the conclusion that Matthew's seismic references collectively indicate (...) that the life, death, and resurrection of Jesus together represent the partial fulfillment of the Old Testament eschatological Day of the Lord. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. (...) The clinical features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

. Science at the interface with society is regarded with mistrust among parts of the public. Scientific judgments on matters of practical concern are not infrequently suspected of being incompetent and biased. I discuss two proposals for remedying this deficiency. The first aims at strengthening the independence of science and suggests increasing the distance to political and economic powers. The drawback is that this runs the risk of locking science in an academic ivory tower. The second proposal favors “counter-politicization” in (...) that research is strongly focused on projects “in the public interest,” that is, on projects whose expected results will benefit all those concerned by these results. The disadvantage is that the future use of research findings cannot be delineated reliably in advance. I argue that the underlying problem is the perceived lack of relevance and reliability and that pluralism is an important step toward its solution. Pluralism serves to stimulate a more inclusive research agenda and strengthens the well-testedness of scientific approaches. However, pluralism also prevents the emergence of clear-cut practical suggestions. Accordingly, pluralism is part of the solution to the credibility crisis of science, but also part of the problem. In order for science to be suitable as a guide for practice, the leeway of scientific options needs to be narrowed – in spite of uncertainty in epistemic respect. This reduction can be achieved by appeal to criteria that do not focus on the epistemic credentials of the suggestions but on their appropriateness in practical respect. (shrink)

Fake research produces results that are invalid from the start. I take such research to be characterised by three jointly sufficient features. It is severely methodologically defective, and the relevant defects support certain nonepistemic (social, political, economic) interests and objectives, while the relevant objectives typically concern the interference with attempts at political regulation. I deal with two kinds of claimed fake research. One is agnotological ploys in which scientific dissent is created by interested parties from industry or politics in order (...) to support their own partisan goals. Another one is the populist antiscience movement that suspects fake research in the scientific mainstream. I suggest three remedies to reduce or eliminate the impact of fake research: disclosing fallacies, improving the understanding of scientific methods, and distinguishing more clearly between science and politics in political decision-making. (shrink)

We reconstruct genetic determinism as a reductionist thesis to the effect that the molecular properties of cells can be accounted for to a great extent by their genetic outfit. The non-reductionist arguments offered at this molecular level often use the relationship between structure and function as their point of departure. By contrast, we develop a non-reductionist argument that is confined to the structural characteristics of biomolecules; no appeal to functions is made. We raise two kinds of objections against the reducibility (...) claim underlying genetic determinism. First, some conceptual distinctions at the protein level cannot be captured on a genetic basis. A one-to-many relationship between DNA sequences and proteins emerges from them. Second, the relationship between genes and proteins is characterized by explanatory loops or reciprocal explanatory dependence. The presence of proteins is explained by the transcription from corresponding DNA sequences, and the latter is in turn accounted for by the action of proteins. By contrast, a reductive account requires a unidirectional explanatory dependence. (shrink)

The traditional mutual support of scientific progress and social advancement has given way to public reservation. Research is no longer considered worthwhile in general. Parts of the public have come to fear both scientific error and scientific success. This raises the question of how to deal with findings that could have a detrimental impact on society. In a different vein, fake research poses a serious challenge to science in that it could undermine the credibility of scientific accounts. Fake research actively (...) produces ignorance rather than knowledge (agnotology). The question is how such actively misleading approaches are to be identified and separated from usual scientific error. (shrink)

I defend the view that propositional knowledge can be defined as follows: A knows that p if and only if A believes that p because p. Spelling out the meaning of 'because' in this formula results in a causal-explanatory view of knowledge.

Many professionals, mainly scientists have told me that a divine being is not necessary to explain why there is something rather than nothing. Theology and even metaphysics are redundant disciplines, they say. To me to reject a discipline a priori is irrational, whereas the methodology of science itself is basically rational. Why do Newton's equations say time is symmetrical, Einstein's relativity and quantum mechanics say time is an illusion and now Smolin says time is reborn - the present moment is (...) a fundamental aspect of reality. Why has matter been the carrier of reality over centuries, then matter dissolves away becoming an ephemeral quantum activity and now information is the carrier of reality? The laws of physics were presumed to be eternal, now Smolin says they are evolving like in biology - natural selection. Why do cosmologists like Brian Greene and Leonard Susskind postulate that there are nearly infinite number of replicas of each and every one of us - doppelgangers - in an infinite number of universes when the gut feeling of each and every one of us that we are unique in this universe? For Newton, gravity was an instantaneous attraction between two masses, for Einstein it was an inherent potential even with a single mass. For Einstein, gravity acts at the speed of light. Plato says that what is observed is phenomena. Reality resides in Platonic Forms. Descartes says that knowledge is acquired through perception and deduction. No reality without the mind. Kant synthesized rationalism and empiricism. Knowledge can be derived without empirical observation. Free will touches almost everything that human beings value. But many scientists postulate that free will is an illusion. Christian theology posits that God created the universe out of nothing. Cosmologists also now say the same thing, but the definition of 'nothing' is disputed. Christian theology once postulated that there is no salvation outside the Church. Now it is not so. Why these confusions? Why these contradictions? On the present methodology of acquisition of knowledge, answers may never be possible. The Theory of Everything (TOE) is more a distant dream than reaching for the stars. However, the discipline of Zygology which is introduced into the academia, a rational explanation why this is not possible has been postulated. Knowledge is holistic - a seamless web runs through all disciplines. Necessity of a new epistemology of reality and existence is inevitable....Zygology may have the answers!". (shrink)

If skepticism is once again fashionable, then much of the credit must go to Peter Unger who gives a sustained defense of an ultra-pyrrhonian position in his book, Ignorance: A case for Skepticism. Starting with a version of the traditional argument that we know nothing about the external world, Unger plunges deeper into skeptical waters by next arguing that there is at most hardly anything which we know to be so; and he scarcely pauses before proceeding to defend the stronger (...) conclusion of ‘universal ignorance,’ the thesis that nobody ever knows anything to be the case. I view Unger's thesis and the arguments that led him to it as a challenge to be overcome, not by an appeal to dogmatism - which Unger sees as the only alternative to skepticism - but by recourse to hard-biting arguments of the sort in which Unger himself puts his faith. In what follows I shall attempt to restate Unger's three main skeptical arguments with a view to showing that their bite is not nearly so hard as he imagines. (shrink)

Bredo C. Johnsen1 misconceives my strictures concerning acceptance of the following principle : If A both knows that p and knows that p entails q, then A can come to know that q.Johnsen seems unaware that my criticism was intended to apply only after is made to appear in its most plausible light; that is, only after its consequent is interpreted as: ’It is logically possible for A to know that q.’ Without this interpretation might be dismissed simply on the (...) grounds that A suffers from some physical or psychological disability that prevents him from drawing inferences from what he knows.Properly interpreted, remains acceptable as long as the propositions substituted for p and q are such that it is at least logically possible for A to get evidence enough to make them known. Agreement on this point is itself enough to render Johnsen's own examples irrelevant. For instance, even though it may be physically impossible for A to get adequate evidence that in the constellation Andromeda there is a planet intermediate in size between Venus and Earth, the foregoing is still a fit substitution instance for q; but since such a q does not suffice to falsify the consequent of, it does nothing to generate any skeptical argument, either. (shrink)

The article explores epistemic and social conditions of the trustworthiness of scientific expertise. I claim that there are three kinds of conditions for the trustworthiness of scientific expertise. The first condition is epistemic and means that scientific knowledge enjoys high credibility. The second condition concerns the significance of scientific knowledge. It means that scientific generalizations are relevant for elucidating the particular cases that constitute the challenges for expert judgment. The third condition concerns the social processes involved in producing science-based recommendations. (...) In this context trust is created by social robustness, expert legitimacy, and social participation. (shrink)

The considerations set out in the paper are intended to suggest that in practical contexts predictive power does not play the outstanding roles sometimes accredited to it in an epistemic framework. Rather, predictive power is part of a network of other merits and achievements. Predictive power needs to be judged differently according to the specific conditions that apply. First, predictions need to be part of an explanatory framework if they are supposed to guide actions reliably. Second, in scientific expertise, the (...) demand for accurate predictions is replaced with the objective of specifying a robust corridor of estimates. Finally, it is highly uncertain to predict the success of research projects. The overall purpose of the paper is to enlarge the debate about predictions by addressing specifically the roles of predictions in application-oriented research. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Moral Traditions: An Introduction to World Religious Ethics, and: Understanding Religious Ethics, and: Moral Struggle and Religious Ethics: On the Person as Classic in Comparative Theological ContextsBrian D. BerryMoral Traditions: An Introduction to World Religious Ethics Mari Rapela Heidt Winona, Minn.: Anselm Academic, 2010. 138 pp. $22.95.Understanding Religious Ethics Charles Mathewes Malden, Mass.: Wiley-Blackwell, 2010. 277 pp. $41.95.Moral Struggle and Religious Ethics: On the Person as Classic in (...) Comparative Theological Contexts David A. Clairmont Malden, Mass.: Wiley-Blackwell, 2011. 245 pp. $99.95These three texts each make significant contributions to comparative religious ethics, a relatively recent discipline that reflects the rise of religious pluralism and globalization. Taken together, these books raise questions about what comparative religious ethics is, how it should be done, and why it should be done. What makes comparative religious ethics “comparative” and to what extent can comparative religious ethics be made genuinely “theological”?Mari Rapela Heidt, who holds a PhD in theological ethics from Marquette University and currently lectures in the religious studies department at the University of Dayton, has written a well-organized and highly accessible introduction to the ethics of the world religions for beginning undergraduate students. Each of the main chapters in her book surveys a major world religion (Hinduism, Buddhism, Judaism, Christianity, Islam, and the Chinese moral tradition) through four lenses: a brief review of the tradition; the moral world of the religion; values, principles, or virtues in the tradition; and the religious tradition on a particular moral issue (e.g., Hinduism on abortion, Buddhism on wealth and poverty, Judaism on the environment, Christianity on war and peace, Islam on men and women, and China’s one-child [End Page 202] policy). The book also includes opening chapters that introduce students to the study of ethics and religious ethics; a final chapter on additional religious moral traditions (Sikhism, Jainism, Bahá’í, and Shinto); sidebars highlighting major religious figures, texts, or events (e.g., Gandhi, Thich Nhat Hanh, Elie Wiesel, the Charter of Medina, and the Cultural Revolution); and discussion questions, bibliography (including visual media), footnotes, a glossary, and an index.Although this book briefly discusses the discipline of comparative religious ethics and some of its descriptive and conceptual methods in its opening chapters, its broad scope and concise treatment mean that the actual task of comparing the similarities and differences in the ethics of the world religions is kept to a minimum. The few detailed comparisons that are made focus largely on Hindu, Buddhist, and Christian understandings of the concepts of reincarnation (29, 34, 64), dharma (18–19, 23–24, 34–35, 64), karma (18–19, 21–23, 35–36, 64), and ahimsa (25–27, 38, 70–71). While the main chapters are organized in a way that facilitates comparison, and discussion questions are included that invite students to observe similarities and differences, the book would be strengthened by giving greater attention to comparison throughout and adding a concluding chapter that summarizes its comparative content. It ends somewhat abruptly with a discussion of the Shinto moral tradition.Charles Mathewes, associate professor of religious studies at the University of Virginia, has written a book that, while limited to Judaism, Christianity, and Islam, achieves much greater comparative sophistication. The text is based on a course he has taught for more than ten years called “Religious Ethics and Moral Problems,” and it bears the marks of a seasoned teacher whose primary audience is advanced undergraduate students, both religious and secular. Mathewes writes from a Protestant Christian perspective “having a strong apocalyptic dimension which is focused on the next life,” acknowledging that Roman Catholics and Eastern Orthodox may find his views “odd or confused” (53). Part 1 discusses the relationship between God and morality and provides an overview of the ethics of each of the three Abrahamic religions. Parts 2 and 3 then examine not only the moral positions but “the arguments animating the traditions” (3) on a wide range of personal and social matters (e.g., friendship, sexuality, marriage and family, lying, forgiveness, capital punishment, war, and the environment). Part 4 turns to the even more ordinary topics of labor, leisure, and life and the more... (shrink)

The aim of this paper is to discuss the relation between the observation basis and the theoretical principles of General Relativity. More specifically, this relation is analyzed with respect to constructive axiomatizations of the observation basis of space-time theories, on the one hand, and in attempts to complete them, on the other. The two approaches exclude one another so that a choice between them is necessary. I argue that the completeness approach is preferable for methodological reasons.

In Bielefeld, Germany in April, 1997 an author conference was devoted to Arthur C. Danto's 1995 Mellon Lectures After the End of Art: Contemporary Art and the Pale of History . This essay provides an introduction to seven essays given at that conference and expanded for this Theme Issue of History and Theory. Danto presented his view of the nature of art in The Transfiguration of the Commonplace . He then added in the Mellon lectures a sociological perspective on the (...) current situation of the visual arts, and an Hegelian historiography. The history of art has ended, Danto claims, and we now live in a posthistorical era. Since in his well-known book on historiography, Analytical Philosophy of History , Danto is unsympathetic to Hegel's speculative ways of thinking about history, his adaptation of this Hegelian framework is surprising. Danto's strategy in After the End of Art is best understood by grasping the way in which he transformed the purely philosophical account of The Transfiguration into a historical account. Recognizing that his philosophical analysis provided a good way of explaining the development of art in the modern period, Danto radically changed the context of his argument. In this process, he opened up discussion of some serious but as yet unanswered questions about his original thesis, and about the plausibility of Hegel's claim that the history of art has ended. (shrink)

Following Karni's seminal work, Walker and other researchers have recently provided gradually convincing evidence that sleep is critical for the consolidation-based enhancement (CBE) of motor sequence learning. Studies in our laboratory using a motor adaptation paradigm, however, show that CBE can also occur after the simple passage of time, suggesting that sleep effects on memory consolidation are task-related, and possibly dependent on anatomically dissociable circuits.

Résumé Appuyée sur une collation systématique — incluant l’orthographe — de l’unique manuscrit subsistant, cette nouvelle édition critique du début de la Logica « Ingredientibus » : Super Porphyrium, accompagnée d’une traduction française inédite et complétée par une abondante annotation, rend ainsi accessible l’exposé le plus détaillé d’Abélard sur les universaux, des pages célèbres où, dans une approche sémantique non exempte de perspectives métaphysiques, on trouve, comme l’étude précédente l’a laissé voir, des développements philosophiques importants relatifs à l’intellection et à (...) l’abstraction.Based on a systematic collation — including the orthography — of the only surviving manuscript, this new critical edition of the beginning of Abelard’s Logica “Ingredientibus” : Super Porphyrium, accompanied by an original French translation and an abundant annotation, thus makes accessible Abelard’s most elaborate account on universals, well known pages where, in a semantical approach non exempt of metaphysical perspectives, one finds, as the preceding study as shown, important philosophical developments on intellection and abstraction. (shrink)

I argue that the time-gap argument poses no objection to Direct Realism. In the case of exploded stars many light years from us, what we see is no longer the star, but its light. I argue that in all cases of seeing we see light, but only when physical objects exist at the time of our seeing do we see them.

United Nations (UN) leaders suggest that the world is not on track to meet the Sustainable Development Goals (SDGs) by 2030. The purpose of this paper is to explore whether the SDGs provide a valuable platform to call for a basic income (BI) globally. Adopting a critical historical studies approach, the article traces the evolution of ‘development’, including the UN decades of development, the Millennium Development Goals, and the SDGs. It subsequently describes the structural adjustment and poverty reduction efforts by (...) the World Bank and International Monetary Fund, and then outlines why the SDG framework may be helpful in advancing a BI. We argue that as climate-related disasters increase, a BI will be vital in providing a modicum of security in an increasingly unstable world. Calls for BI must be anchored to a broader change agenda that recognizes the causes of poverty and income inequality, and seeks their dismantling and redress. (shrink)

Moors and colleagues’ clever studies demonstrate that goal-relevant stimuli can produce rapid, unintentional affective priming, but not necessarily that primes are compared with goal representations following onset. Instead, prior attunements based on changing concerns may prespecify reward value. Even if both these processes count as emotion-relevant appraisal, none of the evidence rules out appraisal-independent emotion under other, unsampled, circumstances, including those where emotions develop as cumulative responses to unfolding and responsive environments rather than as momentary reactions to briefly-presented simple stimuli. (...) Although the functional relations between inputs and outputs may imply “constructive” processes at one level, these processes may be implemented by sequential lower-level mechanisms. (shrink)

From tabloid headlines to scientific discoveries to investigative documentaries, the claim that truth is being revealed is commonplace today. Such attention-grabbing claims can conjure allure, sell products, launch careers, cement authority and much more besides. And yet, despite the familiarity of revelation-talk, this notion has been subject to limited academic theorizing to date outside of matters divine. Revelations sets out to examine both how the making available through revealing is accomplished as well as the implications of revealing. In other words, (...) it is concerned with how revelations are realized and what is realized through them. Central to the argument will be treating attempts to make available as processes that can entail mix - that is, as processes that combine treating truth as publicly demonstrable but also as beyond simple verification, as alternately intelligible but also as unknowable. In taking the pervasive appeal to revealing as its topic, and through drawing inspiration from a range of disciplines, this book should appeal to a variety of audiences; including those interested in secrecy, conspiracy, expertise, celebrity, science and technology. (shrink)