Purpose Intellectual honesty and integrity are the cornerstones of conducting any form of research. Over the last few years, scholars have shown great concerns over questionable research practices (QRPs) in academia. This study aims to investigate the questionable research practices amongst faculty members of medical and dental colleges in Pakistan. Method A descriptive multi-institutional online survey was conducted from June-August 2022. Based on previous studies assessing research misconduct, 43 questionable research practices in four domains: Data collection & storage, Data analysis, (...) Study reporting and Collaboration & authorship were identified and investigated. Descriptive (Frequencies, Percentages, Mean, SD) and Inferential (chi square) statistics were calculated. Results A total of 654 faculty members responded. Every respondent reported committing at least one QRP in their career. The most common QRPs included deliberately failing to mention funding, publishing program evaluation data not meant for research purposes or approved by an ethical body, inappropriately storing identifiable information and non-disclosure of any conflicts. There was significant association of age, gender and academic rank with QRPs in ‘Data collection and storage’ and ‘Data Analysis’ domains. Conclusion Medical and dental faculty members participating in this study are involved in a range of questionable research practices (QRPs) in Pakistan. Their confession might have contributed to the faculty developing self-awareness and reinforcing academic integrity. There is a need for reviewing policies and practices to improve research culture. Future research should explore the factors resulting in such practices. (shrink)

College towns contain mixtures of students and locals, tied to the intitution’s urban life. Due to students’ health, community engagement must be prioritized in these towns. However, technology is often blamed for distancing people. A paradoxical use of it, specifically immersive technology, a youth favorite, can be the solution by focusing on the technological narratives of the institute-related materials to improve community cohesion. This strategy shaped connections between students and locals and among past, present, and future. In this presentation, the (...) impact of immersive technology will be discussed and compared in two college towns, Lancaster, UK, and Lubbock, USA. (shrink)

Background: Dengue Disease is a mosquito-borne tropical disease caused by the dengue virus, symptoms typically begin three to fourteen days after infection. This may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. Dengue serology is applied in different settings, such as for surveillance, in health care facilities in endemic areas and in travel clinics in non-endemic areas. The applicability and quality of serological tests in dengue endemic regions has to be judged against a (...) background of potential cross reactivity with other flavi-viruses, difficulties in distinguishing primary from secondary infections and technological problems related to the fact that most dengue endemic regions are relatively poor of resources .Objectives: to help doctors and patients in diagnosing Dengue Disease and give them the information of how to prevent Dengue Disease and to be able to understand the signs and symptoms of Dengue Disease. Methods: We collected all relevant material for Dengue Disease. Then we designed and implemented a knowledge based system for diagnosing Dengue Disease using SL5 Object Language. Results: The knowledge based system was evaluated by a group of Patients and specialized doctors and they found it very friendly and easy to use. (shrink)

The study adopted a systematic review approach to review the existing studies on the relationship between corporate social responsibility (CSR) and Earnings Management (EM). The aim of this study is to determine whether CSR is an effective tool to promote healthy relationships with stakeholders or CSR is used as an effective strategy by firm's mangers to hide out their involvement in (EM) practices. Results revealed that prior research on the CSR‐EM relationship is limited. The majority of the studies found an (...) inverse relationship between CSR and EM. Moreover, mixed results were reported because of the lack of sufficient theoretical support, inappropriate research designs, and varying approaches to measure CSR and EM. This study also synthesizes the various consistencies and inconsistencies in the existing literature of CSR‐EM and future research agenda. Policymakers should reward organizations that pursue CSR purely for social and environmental concerns and at the same time they should be vigilant for those which use CSR for shielding their EM practices. (shrink)

A compelling argument of how human health is adversely affected by our poor treatment of non-human animals. The author contents that in order to successfully confront the 21st Century's health challenges, we need to broaden the definition of the word 'public' in public health to include non-human animals.

The field of Neuro-Engineering seems to be on the fast track towards accomplishing its ultimate goal of potentially replacing the nervous system in the face of disease. Meanwhile, the patients and professionals involved are continuously dealing with human bodily experience and especially how neuro-engineering devices could become part of a user’s body schema: the domain of ‘embodied phenomenology’. This focus on embodiment, however, is not sufficiently reflected in the current literature on ethical and philosophical issues in neuro-engineering. In this article (...) we will focus on this lacuna by explaining existing data on neuro-engineering user’s experiences by using phenomenological concepts such as transparency and the concepts that may facilitate this: functionality, sensorimotor feedback and affective tolerance. By introducing and applying these concepts to four real life case examples, we will discuss practical implications and guidelines which can contribute to the actual success of incorporation of the device by the patient. First, we will discuss the importance of a ‘Patient Preference Diagnosis’, which can serve as a way to prepare the patient for the existential reorientation involved in the process. In addition, a Patient Transparency Diagnosis during and after such a process is also relevant when wanting to provide the medical field in general with feedback, and the patient in particular with possibilities to fine-tune the device. From these practical guidelines we will conclude that the phenomenological approach can be very valuable when applied to the field of neuro-engineering. (shrink)

Given the increasing frequency of severe weather conditions, it is crucial to reassess our design strategies to establish architectural principles that protect individuals’ emotional and physical health and general welfare. Iranian master builders, known as Ostads, have historically devised effective methods to tackle climate change challenges and improve human comfort. Vernacular architecture in Iran showcases a continuity between its components, local construction processes, climatic adaptation, and cultural integration. Iran’s architectural solutions vary in response to different climatic zones. Vernacular and indigenous (...) Iranian architecture, with a history spanning at least two millennia, demonstrates its adaptability through seamless integration within very different surrounding environments and climates and changing societies over time. The extraordinary buildings created by the Ostads of Iran have effectively enhanced the comfort and well-being of occupants while protecting populations from often already extreme climates. Contemporary architects can utilise Iranian traditional architecture to create cost-effective, comfortable, socially embraced, and environmentally aware communities prepared to withstand the even harsher weather conditions of the future. This research compares traditional and modern architecture of Iran’s residential buildings, designed and constructed from the Qajar era to the present day. The primary emphasis is on analysing specific examples within the Köppen regional division, which is one of the best-known and most efficient approaches for climatic zoning. The Köppen climate classification scheme which uses monthly and annual threshold values of precipitation and temperature. (shrink)

Given the complexity and generalizability of motor skills, it is difficult to account for learning in this area without incorporating the concept of unconscious abstraction. A model based solely on association does not seem to account for data in this domain; specifically, instances that require learners to execute a practiced motor skill in a novel situation.

Writing about the imperative for compassion in universities is not a new endeavour (Gibbs, 2017; Waddington, 2016). However, the ongoing COVID-19 pandemic has underlined a need to address the quest...

Importance of the Small Medium Enterprises sector cannot be overemphasized in the industrial development of a country. 90% of all the enterprises in Pakistan are consisting of Small Medium Enterprises; 80% labor force is employed in non-agriculture sector, Small Medium Enterprises are sharing annually 40% to GDP of the country. However providing huge part in the development of the country Small Medium Enterprises are still encountering with some perilous pitfalls and the survival of the Small Medium Enterprises is getting harder. (...) Now the economy system of the country has been converted from the production based to knowledge-based economy. The review of the previous results pointed out that the twenty first century is the era of technological and intellectual capital and it has added the ultimate importance in the knowledge-based economy. Currently, the economy is based on knowledge-based economy and it is based on the intellectual capital. Therefore, it is difficult for Small Medium Enterprises in Pakistan to transfigure and acquire the concept and applications of intellectual capital in order to counter and mitigate the emerging economics problems. (shrink)

Just Transition, an organizing and policy framework that has emerged from the climate justice movement, is a powerful upstream response to health disparities created by structural subordination. As the public health field pushes itself to address the “cause of causes” of unjust health disparities, Just Transition offers new possibilities for partnership and collective action. We introduce the Just Transition framework, explain its relevance to the concerns of health justice advocates, and provide some examples of how the two movements might work (...) together. (shrink)

This article featuring Pakistan constitutes one of five articles in a collection of essays on local capacity-building in research ethics by graduates from the University of Toronto’s Joint Centre for Bioethics MHSc in Bioethics, International Stream programme funded by the Fogarty International Center for Advanced Study in the Health Sciences (FIC). Research ethics in Pakistan is an emerging field seeking to articulate best ethical standards for research practices. It is best understood as the initiation of a dialogue. Still, there are (...) weak mechanisms for research ethics and there is an absence of mechanisms for monitoring ongoing research, particularly for assessing compliance with the recommendations of ethics review committees. Further, there are few qualified individuals in research ethics in both the private and public sectors. There are multiple challenges associated with research ethics, many of them stemming from issues around development and democratization, which cannot be addressed by guidelines and regulatory processes alone. (shrink)

_The present study delves into the sentiment analysis of Pakistani youth towards TikTok influencers, employing a mixed-methods research design. The data for the present study was collected using a questionnaire consisting of both open-ended and closed-ended items. The data was collected from Pakistani youth ranging from 15 to 30 years of age (timespan was from February 2023 to September 2023). The sample of the study were 300 Pakistani youth, comprising 41.1% males and 58.9% females. Statistical Package for Social Sciences (SPSS-v20) (...) was employed for descriptive statistics and Chi-Square test on quantitative data. While for sentiment analysis of qualitative data Azure Machine Learning add-on was used in Microsoft Excel for polarity categorization of sentiments. Chi-Square statistics revealed that the relationship between age group and following TikTok influencers was statistically significant (p=0.010) while there was no significant correlation between gender and following TikTok influencers (p= 0.421). While the qualitative analysis of the data i.e., content analysis revealed a wide spectrum of emotions and sentiments among the respondents, showcasing a varied significance of the TikTok influencers in shaping their thoughts, perceptions, and worldviews. The study offers both qualitative and quantitative insights to inform ongoing research in the realm of digital culture._. (shrink)

Studies on doctoral education can be categorised into three broad themes: ‘the macro level, the meso level and the micro level’ (Sin and Tavares, 2020, p. 3). Recent years have witnessed a rise in...

The movement against enforced disappearances has been exceptionally strong in Pakistan. It has highlighted the extralegal activities of state actors and has prompted the judiciary to question powerful agencies regarding their conduct. With the help of historical analysis, this article argues that the movement has grown out of the reactions generated by War on Terror in Pakistan. The state’s stance to override human rights for combating terrorism is challenged by a movement which is largely anti-War on Terror and which is (...) strengthened by historical and ideological factors as well as by respect for human rights. The movement against enforced disappearances had thus paved the ground for important debates on human rights in Pakistan. (shrink)

With numerous, and at times, competing demands placed on the academic, what can be done in order to remain well and healthy? Nurturing Wellbeing in Academia by Poppy Gibson is a how-to guide which...

This book provides an original perspective on a range of controversial issues in educational and social research through case studies of multi-disciplinary and mixed-method research involving children, teachers, schools and communities in Europe and the developing world. These case studies from researchers "across continents" and "across disciplines" explore a range of interesting issues, including the relevance of research approaches to very different national settings, and to the kinds of questions being asked; the barriers of language and culture between researcher and (...) researched; articulating the thinking and feelings of very young children; the challenges of dealing with "partiality" of data; issues of identity, subjectivity and reflexivity; and transferring research approaches from one national setting to the problems posed in another. (shrink)

Scholarship on gender and policing has frequently applied gendered organizational theory to understand how this type of organization and the men who run it produce gendered difference and inequity at the workplace. In this article, I draw on ethnographic research on lower ranked policewomen in Pakistan and contend that to fully fathom women’s marginalization at work, an analysis must not limit itself to the organization or the men who create the inequity but must also focus on women’s workplace behavior. My (...) research sheds light on women’s anxieties about working with a large number of men and about people questioning their morality and character because they do so. I also demonstrate how their subsequent coping strategies can impede their professional development and reproduce their marginalization at their workplace. This woman-centric approach, which examines how policewomen navigate gendered landscapes in different patriarchal social spaces, therefore shows that workplace inequity is the collective result of the interplay between different actors and social structures, and leads to a more complex understanding of this phenomenon. (shrink)

Authentic leadership has appeared as a significant field of research. Building on social exchange theory that explicates how individuals mutually mechanize reciprocation and eventually establish a trust-based relationship, we postulated a positive relationship between authentic leadership and followers' organizational citizenship behaviors (OCB). Based on a two-wave time-lagged design, the data were obtained from 270 employees working in the private banking sector of Pakistan. We found that authentic leadership is positively associated with subordinate’s OCB, as well as, leads to a higher (...) level of both affective and cognitive-based followers' trust. The results also indicated that both affective and cognitive-based trust positively mediated the relationship between authentic leadership and OCB. The implication for theory and practice are discussed. (shrink)

This paper examines public conflict over the rapid growth of the Tasmanian salmon aquaculture industry and associated environmental and social impacts. By conducting a media analysis, triangulated...

This research study has done to identify and investigate the major factors behind the excessive usage of Facebook by the youth of Karachi and what kind of impacts they have to face on various aspects of their lives due to this much consumption of Facebook. In this research paper, the researcher has applied both types of methodology, Qualitative as well as Quantitative. The researcher has selected Karachi as the universe of the study. The data has collected in the manner of (...) survey forms filled by students of different universities and colleges of Karachi; aged from 18 to 30 and the sample size is 50 in which half of the population includes males and half females and 10 interviews are also conducted from teachers and parents of Facebook users. This research study raises major points related to the extreme usage of Facebook which includes the mental and physical conditions of adolescents, children’s progress in their academic lives, impacts on relationships and disturbance in routine works. The data has collected in a fair way. The results revealed that Facebook repercussion only happens when an individual is using it in an excessive amount. The researcher suggests that using Facebook could be beneficial only if people learns to use it in manageable levels and if they are able to create a balance between the virtual world and real world. (shrink)

This study analysis of social media marketing includes use of platforms to communicate with consumers, promote items, and influence their decisions. The process by which customers choose which products or services to purchase is known as consumer purchase behaviour. Data was provided for this study, which observed exactly how social media marketing distresses customer buying behaviour, by consuming 350 participants, 150 marketers, and 200 customers. It is understood that many social media marketing features distress and unfair customer decisions. Hypotheses remained (...) established to observe the relationships between commitment to social media marketing content, frequency of commercials, influencer content, and various social media platforms with consumer purchase behavior. Using SPSS logistic and linear regression analyses remained engaged to evaluate these relationships. Results expose that arrangement with social media marketing comfortable and influencer content positively moves buying behaviour. Linear regression analysis verifies these outcomes, proving the power of these relationships and the importance the effect of standard buying behavior. As that, the study delivers proposals concerning the way to use social media marketing approaches to increase consumer appointment and sales. Based on these insights, the study recommends optimizing social media marketing techniques to maximize customer interaction and improve financial outcomes. (shrink)

Apprenticeship has always played both a social and economic role. Today, it forms part of the regeneration strategies of cities in the United Kingdom. This involves the creation and management of complex institutional relationships across the public and private domains of the civic landscape. This paper argues that it is through closely observed analysis of these meso-level developments (in contrast to studies of national systems) that we can reveal how the sustainability of vocational education and training initiatives depends on the (...) generation of civic social capital in the pursuit of collective goals. At the same time, the path-dependent nature of the clustering of social and economic inequality in urban post-industrial settings remains a constant reminder of the scale of the problems confronting all those involved. (shrink)

Downsizing due to COVID-19 and its consequences on laid-off employees has attracted the attention of many researchers, around the globe. However, the underlying mechanisms that explain the effects of COVID-19 downsizing on the employees who have survived cutoffs remain underexplored. Grounded in the conservation of resources theory, this manuscript aims to study the causal path through which COV-DS reduces the survivors’ affective commitment. The current study proposes the mediation of survivors’ job uncertainty, stress, and organizational identification between COV-DS and survivors’ (...) affective commitment. This study also posits the moderating role of transformational leadership between COV-DS and both the mediators. The extant study has employed WARPED partial least square WARP PLS 7 and Hayes Process Macro to test the hypothesized relationships. Using the sample of 274 employees from the private sector of Pakistan, it was found that job uncertainty’s stress strongly mediates the relationship between COV-DS and survivors’ affective commitment. While mediation of survivors’ organizational identification was not proven to be significant. However, with the moderation of transformational leadership, both the mediators were proven to be significant. (shrink)

The ethical aspect of the online learning is a major priority that has to be addressed by all stakeholders in the educational field. This study sheds the light on establishing a code of ethics for the online learning based on a Palestinian vision. A content analysis was used for related literature in order to drive themes and major topics, then a qualitative approach was used to collect data to test the themes from the field. The study population consisted of 21 (...) educators who have previous experience in online learning and 4 key university specialists with pedagogical experience. Interviews and focused group meetings were conducted with participants. The findings revealed that most of educators’ attitudes toward establishing a code for ethics in online learning mode are positive. The study also revealed that all educational stakeholders play a vital role in the success of online learning and particularly in practicing positive ethics. (shrink)

Music education increasingly integrates digital technology to enhance teaching effectiveness and student engagement. This study investigates the impact of technology proficiency on music instruction by analyzing data from 80 music teachers and their students, aged 10-18 years, gathered through a detailed questionnaire. SPSS software was utilized for statistical analysis, including factor analysis, Confirmatory Factor Analysis (CFA), and Structural Equation Modeling (SEM). SEM analysis revealed that Community Influence (CI) and Achievement Prediction (AP) significantly impact Psychological Forecasting (PF), while Technical Expertise (TE) (...) and Educational Technology Proficiency (ETP) have minimal direct effects. Specifically, CI and AP positively influence PF, whereas TE and ETP do not significantly impact PF. The results highlight that social factors and performance expectations are more influential in enhancing teaching outcomes than technological skills alone. (shrink)

Since the advent of the COVID-19 pandemic, the heterogenous discussion on compassion’s purposes in higher education has encompassed the ‘lifeline’ (Parfitt et al., 2021, pp. 181–2) as well as a ‘le...

Music education is one of human kind most universal forms of expression and communication, and it can be found in the daily lives of people of all ages and cultures all over the world. As university life is a time when students are exposed to a great deal of stress, it can have a negative impact on their mental health. Therefore, it is critical to intervene at this stage in their life so that they are prepared to deal with the (...) pressures they will face in the future. The aim of this study was to see how music education affects university students’ mental health, with emotional intelligence functioning as a moderator. The participants in this research were graduate students pursuing degrees in music education. Non probability convenience sampling technique was used to collect and evaluate the data from 265 students studying in different public and private Chinese universities. The data was gathered at a time, and therefore, the study is cross-sectional. The data was collected from January 2022 till the end of March 2022. Many universities have been closed because to COVID-19, therefore data was also gathered online through emails. The data was analyzed quantitatively using the partial least squares –structural equation modeling technique. The findings backed up the hypotheses. The results revealed that there is a significant effect of music education on student’s mental health. Also, emotional intelligence as a moderator significantly and positively moderates the relationship between music education and students’ mental health. Music has numerous physiological aspects, and listening to it on a daily basis may be beneficial to your general health and well-being. Furthermore, musicians and music students with a high level of emotional intelligence have a better chance of not just performing well in school, college and university or in the music industry, but also of maintaining mental health and improving it. (shrink)

The coronavirus pandemic (COVID-19) has badly affected the social, physical, and emotional health of workers, especially those working in the healthcare sectors. Drawing on social exchange theory, we investigated the effects of participative leadership on employees’ workplace thriving and helping behaviors among frontline workers during the COVID-19 pandemic. In addition, we examined the moderating role of a leader’s behavioral integrity in strengthening the relationship between participative leadership, and employees’ workplace thriving and helping behaviors. By using a two-wave time-lagged design and (...) data collected from 244 healthcare workers, a moderated hierarchal regression was implemented to test the proposed hypotheses. As hypothesized, participative leadership predicted employees’ workplace thriving and helping behaviors. The leader’s behavioral integrity strengthened the relationship between participative leadership and employees’ thriving and moderated the relationship between participative leadership helping behaviors. Implications for research, theory, and practice are discussed. (shrink)

Film-based learning projects enhance communication proficiency by immersing students in visual and auditory experiences that improve their understanding, skills, confidence, and creativity in conveying ideas. This study investigates the impact of film-based learning initiatives on students' communication skills through a qualitative methods approach. Data were collected from 150 students using a pre-post-test evaluation, focusing on five key variables: understanding of content, skills improvement, confidence in communication, proficiency in communication, and strategic problem-solving skills. Qualitative data provided a comprehensive understanding of how (...) film-based learning influences communication. It shows students' skills in using SPSS to communicate results from a variety of statistical studies, such as the Wilcoxon signed-rank test and paired sample t-test, which showed a significant improvement in communication ability across these variables. The paired sample t-test highlighted notable gains in communication skills, while the Wilcoxon test confirmed these improvements by analyzing ranks and medians. The findings underscore the effectiveness of film-based interventions in significantly enhancing various aspects of students' communication abilities. (shrink)

Cinematic content plays a crucial role in shaping and reflecting societal attitudes, offering powerful narratives that can influence public perceptions of social issues. This study explores the impact of cinematic content on psychological attitudes towards social issues among college students. A sample of 150 students was divided into two groups: Group A (80 students) impacted the positive attitude while Group B (70 students) served as the control group with negative attitude. This study aimed to assess how cinematic narratives affect attitudes (...) and perceptions of social issues. Statistical methods employed included t-tests to compare attitudes between groups, one-way ANOVA for with-group variations, chi-square tests for categorical relationships, and pre-post tests to measure changes in attitudes. The findings highlight the significant role of cinematic content in shaping the attitudes towards social issues, emphasizing the importance of understanding how films influence public opinion and societal norms. This analysis provides insights into the effectiveness of cinematic portrayals in driving the positive social change and informs content creators on leveraging media for educational and advocacy purposes. (shrink)

This paper provides a critical review of economic outcome metrics used in healthcare value assessment, emphasizing the evolving landscape of resource allocation, patient-centered approaches, and standardization efforts. With healthcare costs rising globally, the efficient allocation of limited resources is essential. Metrics like Quality-Adjusted Life Years (QALYs), Disability-Adjusted Life Years (DALYs), Incremental Cost-Effectiveness Ratios (ICERs), and Cost-Benefit Analysis (CBA) are central to guiding funding decisions, influencing insurance coverage, and shaping treatment prioritization. Emerging trends, such as the integration of artificial intelligence (AI) (...) and big data, are enhancing the precision of these assessments, while patient-centered metrics underscore the importance of patient satisfaction and quality of life. Additionally, there is a growing push for the standardization of these metrics to create consistent frameworks across diverse health systems. This paper explores case studies, practical applications, and future directions to provide insights into how healthcare systems can adopt more effective, globally aligned economic assessments. (shrink)

Stock markets accurately reflect countries’ economic health, and stock returns are tightly related to economic indices. One popular area of financial research is the factors that influence stock returns. Several investigations have frequently cited macroeconomic factors, among numerous elements. Therefore, this study focuses on the empirical analysis of the relationship between macroeconomic factors and stock market returns. When a stock market becomes increasingly volatile, it becomes susceptible to economic uncertainty news, and information on social media platforms. Thus, we incorporated a (...) new dimension of economic uncertainty news sentiment for stock return predictions. We employed the daily data ofgold index, crude oil price, interest rate, exchange rate, and stock returns for a set of countries from January 2010 to December 2020. Subsequently, to compute coefficients, we conducted a regression analysis using one of the more sophisticated approaches: single-layer neural networks and ordinary least square regression. In addition, we only computed EUNS for the period of the fiscal budget announcement for the US, Turkey, and Hong Kong. The results indicate that the gold index, interest rate, and exchange rate are highly significant and negative macroeconomic factors for all analyzed countries. These findings also indicate that EUNS is important and detrimental for projecting stock returns. (shrink)

In sports education, psychological strength is considered as an integral component in the performance of any athlete. One of the effective ways to improve many psychological attributes involves training. The sample consisted of 450 athletes divided into an experimental group (EG) (n = 225) that received eight-week imagination training and a control group (CG) (n = 225) that continued with conventional training. Data was examined using the latest version of SPSS 17.0, using descriptive statistics, paired t-tests, and Analysis of covariance (...) (ANCOVA) to control for pre-existing differences. Psychological strength, mental resilience, focus and concentration, confidence, and stress management are important in athletic performance. It is proposed as a method of enhancing these psychological attributes in sports education. There were differences in significance in the EG in psychological strength, focus and concentration, confidence, and stress management compared with the CG. Paired t-tests in these variables reflect p< 0.05. ANCOVA supported the efficiency of imagination training. Imagination training significantly develops psychological strength and other related attributes in athletes. In all the variables studied, the EG performed better compared to the CG, which provided evidence that imagination training is indeed a helpful tool in enhancing psychological strength and performance in sports education. (shrink)

Since the emergence of Pakistan the history of Pak-Afghan relations can best be analyzed from conflict to cooperation. Some of the early problems are mainly responsible for conflict and cooperation in both countries relations. After the establishment of democratic setup in both states, different CBMs indicate positive sign in Pak-Afghan diplomatic relationship. The drawdown of US forces has created security concern for Pakistan and Afghanistan that the creation of power vacuum can push the country again into civil war like situation. (...) In such state of security Pakistan’s engagement to bring the Taliban to the negotiation table will smooth the way for a broad-based government in Afghanistan. Some of the Afghan domestic political issues also created mistrust i.e., the refugee’s problem, cross border militant’s infiltrations, drug problem and issue of the Taliban. However, the paper will highlight the measures to keep intact the reconciliation more effective and replace the mistrust by trust. How domestic political issues effect their bilateral relations and why various methods taken in the prescribe time not effective in bilateral relations of the two states. (shrink)

Film production is the process of creating a film, involving stages such as progress, pre-production, invention, post-production, and sharing. It encompasses planning, scripting, shooting, editing, and finalizing the film for public viewing. The process of imagination drives innovation in scripting, directing, and cinematography, resulting in unique, engaging experiences that captivate audiences with their emotive stories. The principle of this investigation is to assess how psychological factors add to enhancing imagination in film production, focusing on their impact on creative processes and (...) outcomes. A study surveyed 680 students from college film program students to analyze their creative personality and imaginative capabilities using structured questionnaires. Key psychological constructs included Creative Self-Efficacy, Emotional Resilience, Cognitive Flexibility, and Intrinsic Motivation. The study investigated the impact of psychological factors on college cinema students' creative imagination in filmmaking, demonstrating high validity and reliability with Factor Loadings exceeding 0.76, Composite Reliability higher than 0.88, and Average Variance Extracted (AVE) range as of 0.59 to 0.67. Discriminant validity was confirmed as every construct AVE was better than its square correlations by other constructs. Psychological factors significantly influence film production imagination, fostering creative thinking and emotional depth. Understanding and harnessing these factors enhances storytelling, character development, and audience engagement, ultimately enriching the cinematic experience. (shrink)

Background: Pembrolizumab, an inhibitory anti-PD-1 antibody, has led to significantly meaningful improvements in advanced melanoma. This meta-analysis discusses and presents the efficacy and safety of pembrolizumab versus control treatments in randomized controlled trials. Methods: Electronic databases were searched systematically for RCTs using pembrolizumab in advanced melanomas. Pooled estimates were calculated under random-effect models for overall response rates, PFS, OS, and TRAEs. Results: Nine RCTs including 5132 patients were analyzed. Pembrolizumab significantly realized better results in ORR, PFS and OS HR 0.62, (...) 95% CI 0.54, 0.71, P < 0.001 and HR 0.70, 95% CI 0.63, 0.78, P < 0.001 for control. PFS and OS were consistently better in first, second, and further lines and in groups stratified for PD-L1 status. Grade 3–5 TRAEs were lower with pembrolizumab than with chemotherapy 13.3% vs. 25.9% and ipilimumab 16.9% vs. 27.3%. Conclusions: Pembrolizumab monotherapy meaningfully improves ORRs, delays progression, and prolongs survival in advanced melanoma compared to current standard regimens, with the latter given its favorable toxicity profile. As such, pembrolizumab should be considered the new standard of care for treatment-naïve and previously treated subjects. (shrink)

La celebración del quincuagésimo aniversario de la Sociedad Argentina de Análisis Filosófico se dio en el marco, como es usual en estos casos especiales, de la realización de una edición extraordinaria del tradicional Coloquio Anual de la institución. Para tales fines, la Comisión Directiva conformó un Comité Organizador, del cual tuve el honor de formar parte junto con Leandro Giri, Nicolás Lo Guercio, Andrea Melamed, Danila Suárez Tomé, Damián Szmuc y Paula Teijeiro. Desde el inicio pensamos que el coloquio debía (...) tener un cariz diferente, que fuera la ocasión para que la Sociedad hiciera una revisión de su historia y proyectara su continuidad. En función de tales objetivos se decidió que el Coloquio estuviera conformado por tres instancias. La primera sería una serie de paneles en los que representantes de los diversos grupos de investigación activos de la sociedad dieran cuenta de su visión acerca del pasado, el presente y el futuro en SADAF del área de la filosofía en la que se han especializado. La segunda instancia se desplegaría a través de diversas mesas redondas donde se reflexionaría sobre la historia de diversos aspectos institucionales de la sociedad. Por último, habría una convocatoria abierta que tenía una particularidad: los trabajos a presentar debían ser comentarios críticos de artículos originalmente publicados en la revista de la institución: Análisis Filosófico. De esta manera se pretendía generar las condiciones para una autorreflexión colectiva del significado de SADAF en sus 50 años de existencia como punto de partida para pensar los desafíos filosóficos, metafilosóficos e institucionales por venir. (shrink)

Review of Alberto Moretti, En sayos analíticos, SADAF, Buenos Aires 2020.