Researchers and non-commercial institutions negotiate complex legislation and guidance when planning and conducting research studies. The documents and processes required differ across nations and their regulatory bodies and it can be challenging to conduct an international study, especially for non-commercial organisations. In this study, colleagues from Japan and the UK worked closely together focusing on the legislation, organisations, trial processes, ethics review and quality assurance frameworks of clinical trials in two countries, the UK, demonstrated on the model of practices in (...) the University of Bristol and University Hospital Bristol NHS Foundation Trust, and Japan, based on the model in Kyoto University Hospital. Although the ICH tripartite guidelines were developed with participation from both the EU and Japan the set-up and approval processes for clinical trials are different between the two countries while the expectations for quality assurance are similar. We will argue that the f... (shrink)

The progress of electronic health technologies and biobanks holds enormous promise for efficient research. Evidence shows that studies based on sharing and secondary use of data/samples have the potential to significantly advance medical knowledge. However, sharing of such resources for international collaboration is hampered by the lack of clarity about ethical and legal requirements for transfer of data and samples across international borders. Here, the International Clinical Trial Center Network reports the legal and ethical requirements governing data and sample exchange (...) across four continents. The most recurring requirement is ethical approval, whereas only in specific conditions approval of national health authorities is required. Informed consent is not required in all sharing situations. However, waiver of informed consent is only allowed in certain countries/regions and under certain circumstances. The current legal and ethical landscape appears to be very complex and under constant evolution. Regulations differ between countries/regions and are often incomplete, leading to uncertainty. With this work, ICN illuminates the unmet need for a single international collaborative framework to facilitate DSE. Harmonising requirements for global DSE will reduce inefficiency and waste in research. There are many challenges to realising this ambitious vision, including inconsistent terminology and definitions, and heterogeneous and dynamic legal constraints. Here, we identify areas of agreement and significant difference as a necessary first step towards facilitating international collaboration. We propose the establishment of a working group to continue the comparison across jurisdictions, create a standardised glossary and define a set of basic principles and fundamental requirements for DSE. (shrink)

慶応義塾大学法学部のゼミナール「伊東乾民事訴訟法研究会」の卒業生の会「乾会」による論文集。今回はテーマを民事訴訟法に限ることなく、現在関心を持っている法律分野について執筆した。.

For each intermediate propositional logicJ, J * denotes the least predicate extension ofJ. By the method of canonical models, the strongly Kripke completeness ofJ *+D(=x(p(x)q)xp(x)q) is shown in some cases including:1. J is tabular, 2. J is a subframe logic. A variant of Zakharyashchev's canonical formulas for intermediate logics is introduced to prove the second case.

This volume presents the first unabridged translation of Ito Jinsai's (1627-1705) masterwork, the Gomo jigi (Philosophical Lexicography of the Analects and ...

We found that children sometimes abused a social robot placed in a shopping mall hallway. They verbally abused the robot, repeatedly obstructed its path, and sometimes even kicked and punched the robot. To investigate the reasons for the abuse, we conducted a field study in which we interviewed visiting children who exhibited serious abusive behaviors, including physical contact. We analyzed interview contents to determine whether the children perceived the robot as human-like, why they abused it, and whether they thought that (...) the robot would suffer from their abusive behavior. We obtained valid interviews from 23 children over 13 days of observations. We found that 1) the majority of the children engaged in abuse because they were curious about the robot’s reactions or enjoyed abusing it and considered it human-like, and 2) about half of them believed the robot was capable of perceiving their abusive behaviors. (shrink)

偶然性や身体論などこれまで論じてきた問題にもさらに深いまなざしを向けつづける著者による集大成。.

This chapter contains section titled: Hume as Economist Hume's Philosophical Economics Luxury, Knowledge, and Economic Development Money and International Trade Quantity Theory Reconsidered Manners and Diversity of Economic Development Conclusion: Economics and Civilization References Further Reading.

Hume’s economic essays were part of his early project of politics as one of the principal departments of the Science of Man, a project realized, first, by the morals expounded in Book 3 of the Treatise; second, by the politics and criticism in Essays Moral and Political; and third, by economic and political essays in the Political Discourses. The author sheds new light on the way in which Hume’s economic theory was developed as an integral part of his grand philosophical (...) project, one based on the theory of causal reasoning that served Hume’s theorizing throughout his social science in general and his economics in particular. A profound connection is shown between Hume’s philosophy and economics, mainly from a methodological point of view, by highlighting his theory of causation. The strictly philosophical nature and origin of Hume’s “economics” demonstrates the significant difference between his economic writings and those of his contemporaries. (shrink)

This paper reports the results of questionnaire-based research conducted at an exhibition of interactive humanoid robots that was held at the Osaka Science Museum, Japan. The aim of this exhibition was to investigate the feasibility of communication robots connected to a ubiquitous sensor network, under the assumption that these robots will be practically used in daily life in the not-so-distant future. More than 90,000 people visited the exhibition. A questionnaire was given to the visitors to explore their opinions of the (...) robots. Statistical analysis was done on the data of 2,301 respondents. It was found that the visitors’ opinions varied according to age; younger visitors did not necessarily like the robots more than elderly visitors; positive evaluation of the robots did not necessarily conflict with negative evaluations such as anxiety; there was no gender difference; and there was almost no correlation between opinions and the length of time spent near the robots. (shrink)

This study investigated the circumstances and problems that departments of forensic medicine encounter with bereaved families regarding samples obtained from medico-legal autopsies. A questionnaire was posted to all 76 departments of forensic medicine performing medico-legal autopsies in Japan, and responses were received from 48 . Of the respondents, 12.8% had approached and communicated with bereaved families about collecting samples from the deceased person during an autopsy and the storage of the samples. In addition, 23.4% of these had informed families that (...) samples might be used in research. Eighteen departments had received enquiries and requests from families about the samples, with most requests concerning their return. The response to such requests varied according to the department. Few departments interacted with the bereaved families regarding the procedure for obtaining autopsy samples, and their methods for handling family concerns differed depending on the person within the department authorised to contact the family. Moreover, the procedures for engaging in such communication have long been unclear, and no legal or ethical consensus or agreement with the general public has been established. It is important for researchers to further discuss the correct way for forensic medicine departments to communicate with bereaved families. (shrink)

According to the widespread use of Web Services, composition of multiple services is becoming a main issue. BPEL was proposed as a Web Services workflow language in this context. Then, in many cases we need much interactions between a service requester and a BPEL process execution engine. However for the end user under the ubiquitous environment where the service is executed with a cellular phone or PDA, the interaction means simply a burden. The reason is: (1)it is hard to carry (...) out the operation manually, (2)a network connection is unstable, (3)a connection charge is relatively high. In this paper, we propose middle agents between ubiquitous users and Web Services. The agents analyze BPEL, extract the interaction which the ubiquitous users would need, then produce action operators. It makes a plan in order to achieve a service request from the user. Here the planning agent can reduce operations of the user by collecting the necessary information at the beginning which will be inputted during the IP execution. We show the architecture of the agents and an example regarding ATM service, then evaluate the number of inputs, the performance, and the quantity of data transmitted on network. Finally, we consider adaptability of this approach to generic BPEL flow. (shrink)

Spatial metaphors of affect display remarkable consistencies across languages in mapping sensorimotor experiences onto emotional states, reflecting a great degree of similarity in how our bodies register affect. At the same time, however, affect is complex and there is more than a single possible mapping from vertical spatial concepts to affective states. Here we consider a previously unreported case of spatial metaphors mapping down onto desirable, and up undesirable emotional experiences in Mlabri, an Austroasiatic language of Thailand and Laos, making (...) a novel contribution to the study of metaphor and Cognitive Linguistics. Using first-hand corpus and elicitation data, we examine the metaphorical expressions: klol jur ‘heart going down’ and klol khɯn ‘heart going up’/klol kɔbɔ jur ‘heart not going down’. Though reflecting a metaphorical mapping opposite to the commonly reported happy is up metaphor, which is said to link to universal bodily correlates of emotion, the Mlabri metaphors are far from idiosyncratic. Rather, they are grounded in the bodily experience of positive low-arousal states, and in that reflect an emic view of ideal affect centered on contentment and tranquility. This underscores the complexity of bodily experience of affect, demonstrating that cultures draw on the available sensorimotor correlates of emotion in distinct ways. (shrink)

To investigate how bereaved families felt about the explanation received before and after forensic autopsies, the authors conducted a cross-sectional survey of the bereaved families whose next of kin underwent a forensic autopsy at the two Departments of Forensic Medicine and a few bereaved families of crime victims. Of 403 questionnaires sent, 126 families responded. Among 81.5% of the respondents who received an explanation from policemen before the autopsy, 78.8% felt that the quality of the explanation was poor or improper. (...) In Japan, the law has restricted disclosure of information from a forensic autopsy. Despite legal restrictions, 82% wanted to hear from the person who conducted the autopsy. However, police explained the results of autopsy to 65.2% of respondents. Among the families whose frustration and anger increased after autopsy, 86.4% had not been satisfied with the explanation before the autopsy. Additionally, 57.7% had not been informed on the autopsy findings at the time of the questionnaire when more than 2 years had passed after the autopsy. These results reminded us of the importance of an explanation before and shortly after a forensic autopsy for a better understanding and acceptance by bereaved families. (shrink)

Negative attitudes toward robots are considered as one of the psychological factors preventing humans from interacting with robots in the daily life. To verify their influence on humans‘ behaviors toward robots, we designed and executed experiments where subjects interacted with Robovie, which is being developed as a platform for research on the possibility of communication robots. This paper reports and discusses the results of these experiments on correlation between subjects’ negative attitudes and their behaviors toward robots. Moreover, it discusses influences (...) of gender and experience of real robots on their negative attitudes and behaviors toward robots. (shrink)

We generalize the incompleteness proof of the modal predicate logic Q-S4+ p p + BF described in Hughes-Cresswell [6]. As a corollary, we show that, for every subframe logic Lcontaining S4, Kripke completeness of Q-L+ BF implies the finite embedding property of L.

To investigate whether people with social anxiety have less actual and “anticipatory” anxiety when interacting with a robot compared to interacting with a person, we conducted a 2 × 2 psychological experiment with two factors: social anxiety and interaction partner. The experiment was conducted in a counseling setting where a participant played the role of a client and the robot or the confederate played the role of a counselor. First, we measured the participants’ social anxiety using the Social Avoidance and (...) Distress Scale, after which, we measured their anxiety at two specific moments: “anticipatory anxiety” was measured after they knew that they would be interacting with a robot or a human confederate, and actual anxiety was measured after they actually interacted with the robot or confederate. Measurements were performed using the Profile of Mood States and the State–Trait Anxiety Inventory. The results indicated that participants with higher social anxiety tended to feel less “anticipatory anxiety” and tension when they knew that they would be interacting with robots compared with humans. Moreover, we found that interaction with a robot elicited less tension compared with interaction with a person regardless of the level of social anxiety. (shrink)

A great deal of research has been performed recently on robots that feature functions for communicating with humans in daily life, i.e., communication robots. We consider it important to develop methods to measure humans’ attitudes and emotions that may prevent them from interaction with communication robots, as indices to study short-term and long-term interaction between humans and communication robots. This study is aimed at exploring the influence of negative attitudes toward robots, focusing on applications of communication robots to daily-life services. (...) First, a scale of negative attitudes toward robots consisting of three subordinate scales, “negative attitudes toward situations of interaction with robots,” “negative attitudes toward the social influence of robots,” and “negative attitudes toward emotions in interaction with robots,” was developed based on a data sample comprising of 263 Japanese university students. This scale was administered to 240 Japanese university students to confirm its validity and reliability. In this paper, we report on the results of analyses of these data samples. Moreover, we discuss some future problems including a comparison of attitudes toward robots between nations. (shrink)

Although Japanese society has become aware of some types of robots, social acceptance of robots is still not widespread. This study conducted an online questionnaire survey to investigate the relationships between experiences with and knowledge of vacuum, pet-type, and communication robots and acceptance of these robots, including the intention to use and trust. The results suggested that experiences with, knowledge of functions, and acceptance of the robots differed depending on the type of robot, and the influence of these factors on (...) acceptance of the robots also differed depending on the robot types. (shrink)

Reinforcement learning has recently received much attention as a learning method for complicated systems, e.g., robot systems. It does not need prior knowledge and has higher capability of reactive and adaptive behaviors. However increase in dimensionality of the action-state space makes it diffcult to accomplish learning. The applicability of the existing reinforcement learning algorithms are effective for simple tasks with relatively small action-state space. In this paper, we propose a new reinforcement learning algorithm: “Q-learning with Dynamic Structuring of Exploration Space (...) Based on Genetic Algorithm ”. The algorithm is applicable to systems with high dimensional action and interior state spaces, for example a robot with many redundant degrees of freedom. To demonstrate the effectiveness of the proposed algorithm simulations of obstacle avoidance by a 50 links manipulator have been carried out. It is shown that effective behavior can be learned by using the proposed algorithm. (shrink)

The concept of the ‘island’ constitutes a unique theme in Deleuze's thought: desert islands and perversion, continental islands and isolated islands, the connection between the emergence of life and orogeny, the relationship between imagination and islands, and the sea as a rhizome. To think from this point of view on Japan, it is neither an isolated island nor an oceanic island in Deleuze's sense. Rather, it is a place where a unique stratum of thought has accumulated like a multilayered plateau. (...) Japan has often been portrayed as a malignant kind of rhizome, as an oriental land, a land of animism. However, the Japanese islands, as part of the Pacific Rim island arc, and, on the other hand, as a place which bears the forces from the continent, can also be depicted as a manifold location, bearing the rhizome called the sea in a unique way. Not only does it have only a virtual signifier = signifiant of One-ness, but it can also be said to hold multiple strata of signifiers = signifiants within its arc between the continent and ocean. My aim in this paper is to explicate this place called ‘Japan’ as a case study of what Deleuze calls geophilosophy in his last book with Guattari, What is Philosophy? (shrink)

構造主義からアクターネットワークセオリーまで、哲学と人類学という二つの知的実践は交錯してきた。その現代的な意義を考える。 ドゥルーズ=ガタリ、メルロ=ポンティ、サルトル、モース、デュルケム、ヴィヴェイロス・デ・カストロ、デスコラ、ストラザーン――いずれも「自然」をめぐり、レヴィ=ストロースの神話論理の再解釈や「構造」の捉 えなおしとして進行してきた哲学と人類学について、思考様式の違いや歴史的な影響関係、主題の反復を浮き彫りにする。.

Krueger & Funder (K&F) spend too much time on their critique of some classic studies in social psychology. They should have spent more time developing their constructive ideas about better methodologies and, especially, better conceptual foundations for the field. We endorse their exhortation to consider social behavior in its ecologically adaptive context, and we present a few ideas of our own about how to develop a more comprehensive conceptual framework.