Researchers and non-commercial institutions negotiate complex legislation and guidance when planning and conducting research studies. The documents and processes required differ across nations and their regulatory bodies and it can be challenging to conduct an international study, especially for non-commercial organisations. In this study, colleagues from Japan and the UK worked closely together focusing on the legislation, organisations, trial processes, ethics review and quality assurance frameworks of clinical trials in two countries, the UK, demonstrated on the model of practices in (...) the University of Bristol and University Hospital Bristol NHS Foundation Trust, and Japan, based on the model in Kyoto University Hospital. Although the ICH tripartite guidelines were developed with participation from both the EU and Japan the set-up and approval processes for clinical trials are different between the two countries while the expectations for quality assurance are similar. We will argue that the f... (shrink)

Probability theory promises to deliver an exact and unified foundation for inquiry in epistemology and philosophy of science. But philosophy of religion is also fertile ground for the application of probabilistic thinking. This volume presents original contributions from twelve contemporary researchers, both established and emerging, to offer a representative sample of the work currently being carried out in this potentially rich field of inquiry. Grouped into five parts, the chapters span a broad range of traditional issues in religious epistemology. The (...) first three parts discuss the evidential impact of various considerations that have been brought to bear on the question of the existence of God. These include witness reports of the occurrence of miraculous events, the existence of complex biological adaptations, the apparent 'fine-tuning' for life of various physical constants and the existence of seemingly unnecessary evil. The fourth part addresses a number of issues raised by Pascal's famous pragmatic argument for theistic belief. A final part offers probabilistic perspectives on the rationality of faith and the epistemic significance of religious disagreement. (shrink)

As the ongoing literature on the paradoxes of the Lottery and the Preface reminds us, the nature of the relation between probability and rational acceptability remains far from settled. This article provides a novel perspective on the matter by exploiting a recently noted structural parallel with the problem of judgment aggregation. After offering a number of general desiderata on the relation between finite probability models and sets of accepted sentences in a Boolean sentential language, it is noted that a number (...) of these constraints will be satisfied if and only if acceptable sentences are true under all valuations in a distinguished non-empty set W. Drawing inspiration from distance-based aggregation procedures, various scoring rule based membership conditions for W are discussed and a possible point of contact with ranking theory is considered. The paper closes with various suggestions for further research. (shrink)

It is well known that classical, aka ‘sharp’, Bayesian decision theory, which models belief states as single probability functions, faces a number of serious difficulties with respect to its handling of agnosticism. These difficulties have led to the increasing popularity of so-called ‘imprecise’ models of decision-making, which represent belief states as sets of probability functions. In a recent paper, however, Adam Elga has argued in favour of a putative normative principle of sequential choice that he claims to be borne out (...) by the sharp model but not by any promising incarnation of its imprecise counterpart. After first pointing out that Elga has fallen short of establishing that his principle is indeed uniquely borne out by the sharp model, I cast aspersions on its plausibility. I show that a slight weakening of the principle is satisfied by at least one, but interestingly not all, varieties of the imprecise model and point out that Elga has failed to motivate his stronger commitment. (shrink)

Aulisio and Arora argue that the moral significance of value imposition explains the moral distinction between traditional conscientious objection and non-traditional conscientious objection. The former objects to directly performing actions, whereas the latter objects to indirectly assisting actions on the grounds that indirectly assisting makes the actor morally complicit. Examples of non-traditional conscientious objection include objections to the duty to refer. Typically, we expect physicians who object to a practice to refer, but the non-traditional conscientious objector physician refuses to refer. (...) Aulisio and Arora argue that physicians have a duty to refer because refusing to do so violates the patient’s values. While we agree with Aulisio and Arora’s conclusions, we argue value imposition cannot adequately explain the moral difference between traditional conscientious objection and non-traditional conscientious objection. Treating autonomy as the freedom to live in accordance with one’s values, as Aulisio and Arora do, is a departure from traditional liberal conceptions of autonomy and consequently fails to explain the moral difference between the two kinds of objection. We outline how a traditional liberal understanding of autonomy would help in this regard, and we make two additional arguments—one that maintains that non-traditional conscientious objection undermines society’s autonomy, and another that maintains that it undermines the physician-patient relationship—to establish why physicians have a duty to refer. (shrink)

In a recent pair of publications, Richard Bradley has offered two novel no-go theorems involving the principle of Preservation for conditionals, which guarantees that one’s prior conditional beliefs will exhibit a certain degree of inertia in the face of a change in one’s non-conditional beliefs. We first note that Bradley’s original discussions of these results—in which he finds motivation for rejecting Preservation, first in a principle of Commutativity, then in a doxastic analogue of the rule of modus ponens —are problematic (...) in a significant number of respects. We then turn to a recent U-turn on his part, in which he winds up rescinding his commitment to modus ponens, on the grounds of a tension with the rule of Import-Export for conditionals. Here we offer an important positive contribution to the literature, settling the following crucial question that Bradley leaves unanswered: assuming that one gives up on full-blown modus ponens on the grounds of its incompatibility with Import-Export, what weakened version of the principle should one be settling for instead? Our discussion of the issue turns out to unearth an interesting connection between epistemic undermining and the apparent failures of modus ponens in McGee’s famous counterexamples. (shrink)

Crispin Wright’s discussion of the notion of ‘transmission-failure’ promises to have important philosophical ramifications, both in epistemology and beyond. This paper offers a precise, formal characterisation of the concept within a Bayesian framework. The interpretation given avoids the serious shortcomings of a recent alternative proposal due to Samir Okasha.

Buddhism originated and developed in an Indian cultural context that featured many first-person practices for producing and exploring states of consciousness through the systematic training of attention. In contrast, the dominant methods of investigating the mind in Western cognitive science have emphasized third-person observation of the brain and behavior. In this chapter, we explore how these two different projects might prove mutually beneficial. We lay the groundwork for a cross-cultural cognitive science by using one traditional Buddhist model of the mind (...) – that of the five aggregates – as a lens for examining contemporary cognitive science conceptions of consciousness. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Full Collection of Personal NarrativesJake Beery, Neethi Pinto, Marcia King, Laura Wachsmuth, Alisha, Katie L. Gholson, T.S. Moran, Calvin R. Gross, Joanne Alfred, Cindy Bitter, Jenna Bennett, Nadia Khan, Clarice Douille, Kristen Carey Rock, Adrienne Feller Novick, Andrea Eisenberg, Japmehr Sandhu, Katherine Bakke, Heer Hendry, Karan K. Mirpuri, and Katerina V. Liong• Being the Difference• Grieving One More Time• Echoes of Grief: Tales from an Emergency Medicine and Critical (...) Care Nurse• Searching for Peace in Death• “I’d Love to go Off the Grid and Never Come Back”• “A Mother’s Love”• Tiny Person, Big Impact• Night Shift• Cracked Armor• Who Tells the Story• Navigating Hard Situations that Medical School Cannot Prepare You For• The Wish• Break• Five More Minutes• I Saw My Reflection• The Aftermath• Where the Journey Begins• Lessons Learned in Room 208• Joint and Grief Aches• My First Loss: Carrying His Legacy• Grieving the Loss of What Medicine Was Supposed to BeCopyright © 2024 Johns Hopkins University Press... (shrink)

Background: Doping has been a prominent issue for the sport of athletics in recent years. The endurance disciplines, which currently account for 56% of the global anti-doping rule violations in athletics, appear to be particularly high risk for doping.Objective: Using this high-risk, high-pressure context, the main purpose of this study was to investigate the human impact of doping and anti-doping on “clean” athletes. The secondary aim of the study was to better understand the reasons for, and barriers to, competing “clean” (...) among this group of athletes.Method: Semi-structured interviews were conducted with 11 elite distance runners from the UK to explore: the reasons and motivations for competing clean. Perceptions of the anti-doping system, and experiences of being part of that system. Views on the prevalence and causes of doping and the impact of doping on the lives of clean athletes. The interviews were audio-recorded, transcribed verbatim, and analysed using Reflexive Thematic Analysis.Results: Four major themes were identified: The participants in this study have not been tempted to use prohibited substances or methods; they compete in their sport for the personal satisfaction of seeing how good they can be, rather than in pursuit of winning at all costs. Anti-doping does not currently prevent doping effectively and is not implemented evenly across the globe. Doping was perceived as a major issue and was felt to be borne out of certain sporting cultures in which doping is enabled. Doping has impacted the careers of clean athletes in irreversible ways and presents a continuing challenge to the psychological preparation for competition.Conclusions: Clean athletes suffer negative consequences from both doping and anti-doping. ADOs must collaborate across borders to ensure a more even implementation of anti-doping activities, to facilitate a more level playing field on the global stage. ADOs must also acknowledge the existence of a large group of athletes who would never consider deliberately doping and make anti-doping work for these athletes too. (shrink)

Are ecosystems morally considerable-that is, do we owe it to them to protect their “interests”? Many environmental ethicists, impressed by the way that individual nonsentient organisms such as plants tenaciously pursue their own biological goals, have concluded that we should extend moral considerability far enough to include such organisms. There is a pitfall in the ecosystem-to-organism analogy, however. We must distinguish a system’s genuine goals from the incidental effects, or byproducts, of the behavior of that system’s parts. Goals seem capable (...) of giving rise to interests; byproducts do not. It is hard to see how whole ecosystems can be genuinely goal-directed unless group selection occurs at the community level. Currently, mainstream ecological and evolutionary theory is individualistic. From such a theory it follows that the apparent goals of ecosystems are mere byproducts and, as such, cannot ground moral considerability. (shrink)

Ewing, Harley; Ewing, Selena Review of: On Killing: The Psychological Cost of Learning to Kill in War and Society, by Lt. Col. Dave Grossman, Back Bay Books, 1995.

It appears to have gone unnoticed in the literature that Pollock's widely endorsed analysis of evidential defeat entails a remarkably strong symmetry principle, according to which, for any three propositions D, E and H, if both E and D provide a reason to believe H, then D is a defeater for E's support for H if and only if, in turn, E is a defeater for D's support for H. After illustrating the counterintuitiveness of this constraint, a simple, more suitable, (...) alternative to the Pollockian account is offered. (shrink)

This essay presents deductive arguments to an introductory-level audience via a discussion of Aristotle's three types of rhetoric, the goals of and differences between deductive and non-deductive arguments, and the major features of deductive arguments (e.g., validity and soundness).

A progressive and uncompromising work that merges fiction and theory to create an intense yet gloriously deviant look at the world through the eyes of controversial Brit-artist, Jake Chapman (of the Chapman Brothers). With protagonists who -- like his mutated Nike-wearing child mannequins -- exhibit similar aberrations, Chapman engages with Freudian theory, genetic engineering and consumerism, to create a highly original and intellectually stimulating work that is as challenging and confrontational as any of his acclaimed works of art.

In a recent article for this journal, Bryan Pilkington makes a number of critical observations about one of our arguments for non-traditional medical conscientious objectors’ duty to refer. Non-traditional conscientious objectors are those professionals who object to indirectly performing actions—like, say, referring to a physician who will perform an abortion. In our response here, we discuss his central objection and clarify our position on the role of value conflicts in non-traditional conscientious objection.

A survey of the recent literature suggests that physicians should engage religious patients on religious grounds when the patient cites religious considerations for a medical decision. We offer two arguments that physicians ought to avoid engaging patients in this manner. The first is the Public Reason Argument. We explain why physicians are relevantly akin to public officials. This suggests that it is not the physician’s proper role to engage in religious deliberation. This is because the public character of a physician’s (...) role binds him/her to public reason, which precludes the use of religious considerations. The second argument is the Fiduciary Argument. We show that the patient-physician relationship is a fiduciary relationship, which suggests that the patient has the clinical expectation that physicians limit themselves to medical considerations. Since engaging in religious deliberations lies outside this set of considerations, such engagement undermines trust and therefore damages the patient-physician relationship. (shrink)

Cognitive biases can lead to misinterpretations of human and non-human biology and behavior. The concept of the Umwelt describes phylogenetic contrasts in the sensory realms of different species and has important implications for evolutionary studies of cognition (including biases) and social behavior. It has recently been suggested that the microbiome (the diverse network of microorganisms in a given environment, including those within a host organism such as humans) has an influential role in host behavior and health. In this paper, we (...) discuss the host’s microbiome in relation to cognitive biases and the concept of the Umwelt. Failing to consider the role of host–microbiome (collectively termed a “holobiont”) interactions in a given behavior, may underpin a potentially important cognitive bias – which we refer to as the Holobiont Blindspot. We also suggest that microbially mediated behavioral responses could augment our understanding of the Umwelt. For example, the potential role of the microbiome in perception and action could be an important component of the system that gives rise to the Umwelt. We also discuss whether microbial symbionts could be considered in System 1 thinking – that is, decisions driven by perception, intuition and associative memory. Recognizing Holobiont Blindspots and considering the microbiome as a key factor in the Umwelt and System 1 thinking has the potential to advance studies of cognition. Furthermore, investigating Holobiont Blindspots could have important implications for our understanding of social behaviors and mental health. Indeed, the way we think about how we think may need to be revisited. (shrink)

Através desse diálogo tivemos o objetivo de propor uma compreensão do homem através da explicitação do sentido ético de edificação. Apresentamos a cidadania do mundo como uma finalidade moral do homem, que estava presente e oculta na fundamentação metafísica do humanismo. Agora, se o antropológico se fortalece por meio da realização ética do mundo, defendemos que o dever do melhor não é uma finalidade moral que se realiza em um infinito separado da finitude humana. O antropológico só é cidadão se (...) ele se compreende como uma finitude sem infinito separado, ou seja, como um fim em si, como um lugar de chegada. (shrink)

ABSTRACT In this article I read Freud’s theory of dream condensation alongside Blanchot and Derrida’s analysis of the literary fragment. Both these thinkers describe how an imperturbable secret provides an excess that calls out for a response. I thus analyze the structure of dream interpretation as one where the latent dream thoughts respond to a call imbedded in the condensed dream-content. Through a deconstructive reading of Freud and a quote by Nietzsche, I argue that the structure of this call is (...) the condensation of the secret, which is both a mark and occurrence of forgetting. (shrink)

After a number of decades of research into the dynamics of rational belief, the belief revision theory community remains split on the appropriate handling of sequences of changes in view, the issue of so-called iterated revision. It has long been suggested that the matter is at least partly settled by facts pertaining to the results of various single revisions of one’s initial state of belief. Recent work has pushed this thesis further, offering various strong principles that ultimately result in a (...) wholesale reduction of iterated to one-shot revision. The present paper offers grounds to hold that these principles should be significantly weakened and that the reductionist thesis should ultimately be rejected. Furthermore, the considerations provided suggest a close connection between the logic of iterated belief change and the logic of evidential relevance. (shrink)

In a recent article, Douven and Williamson offer both (i) a rebuttal of various recent suggested sufficient conditions for rational acceptability and (ii) an alleged ‘generalization’ of this rebuttal, which, they claim, tells against a much broader class of potential suggestions. However, not only is the result mentioned in (ii) not a generalization of the findings referred to in (i), but in contrast to the latter, it fails to have the probative force advertised. Their paper does however, if unwittingly, bring (...) us a step closer to a precise characterization of an important class of rationally unacceptable propositions—the class of lottery propositions for equiprobable lotteries. This helps pave the way to the construction of a genuinely lottery-paradox-proof alternative to the suggestions criticized in (i). (shrink)

In this article, I examine stigmatizing and especially patronizing attitudes towards others’ depression that people who are well-intentioned produce. The strategy of the article is to consider the social experience of depression through two separate subfields of philosophy: epistemic injustice and phenomenology. The solution that I propose is a phenomenological account of empathy. The empathetic attitude that I argue for involves actively listening to the depressed individual and taking their depression testimony as direct evidence. The article has been written both (...) for those who seek to better support neurodiverse people in their lives and for depressives (and other neurodivergents) themselves in order to provide them with a better account for advocating for themselves against social stigma. (shrink)

This article provides a discussion of the principle of transmission of evidential support across entailment from the perspective of belief revision theory in the AGM tradition. After outlining and briefly defending a small number of basic principles of belief change, which include a number of belief contraction analogues of the Darwiche-Pearl postulates for iterated revision, a proposal is then made concerning the connection between evidential beliefs and belief change policies in rational agents. This proposal is found to be suffcient to (...) establish the truth of a much-discussed intuition regarding transmission failure. (shrink)

Scholars who engage with texts that were written by George Herbert Mead (e.g., 1925e.g., 1926e.g., 1929e.g., 1932e.g., 1938) in the latter half of the 1920s are faced with the task of comprehending Mead’s interpretation of relativity theory and also understanding why relativity theory was considered by Mead to have such profound implications for his own philosophy. As several scholars of Mead’s work have explained (e.g., Joas 1997; Martin 2007; Rosenthal and Bourgeois 1991), Mead was a realist. Mead opposed psychophysical dualism (...) (Cook 1979) and both the behaviorist and the idealist implications that could follow from such a dualism. He wanted to explain human conduct in terms of the self-determination of human .. (shrink)

Reductive accounts of the direction of time are often paired with Humean accounts of laws, while non-reductive accounts of time are often paired with anti-Humean accounts of laws. The traditional pairing of views has recently come under question. This paper aims to clarify what sorts of anti-Humean views motivate anti-reductionism about the direction of time. It is argued that those who think (i) that the laws are metaphysically fundamental, and (ii) that the laws contain time-asymmetric contents, should treat the arrow (...) of time as metaphysically fundamental. (shrink)

In a recent article for this journal, Morten Magelssen argues that the right to conscientious objection in healthcare is grounded in the moral integrity of healthcare professionals, a good for both professionals and society. In this paper, I argue that there is no right to conscientious objection in healthcare, at least as Magelssen conceives of it. Magelssen’s conception of the right to conscientious objection is too expansive in nature. Although I will assume that there is a right to conscientious objection, (...) it does not extend to objections that are purely religious in nature.[i][1] Thus, this right is considerably more restricted than Magelssen thinks. In making my case, I draw on John Rawls’s later work in arguing for the claim that conscientious objection based on purely religious considerations fails to benefit society in the appropriate way. [1]: #fn-1. (shrink)

Organizations are making massive investments in artificial intelligence, and recent demonstrations and achievements highlight the immense potential for AI to improve organizational and human welfare. Yet realizing the potential of AI necessitates a better understanding of the various ethical issues involved with deciding to use AI, training and maintaining it, and allowing it to make decisions that have moral consequences. People want organizations using AI and the AI systems themselves to behave ethically, but ethical behavior means different things to different (...) people, and many ethical dilemmas require trade-offs such that no course of action is universally considered ethical. How should organizations using AI—and the AI itself—process ethical dilemmas where humans disagree on the morally right course of action? Though a variety of ethical AI frameworks have been suggested, these approaches do not adequately address how people make ethical evaluations of AI systems or how to incorporate the fundamental disagreements people have regarding what is and is not ethical behavior. Drawing on moral foundations theory, we theorize that a person will perceive an organization’s use of AI, its data procedures, and the resulting AI decisions as ethical to the extent that those decisions resonate with the person’s moral foundations. Since people hold diverse moral foundations, this highlights the crucial need to consider individual moral differences at multiple levels of AI. We discuss several unresolved issues and suggest potential approaches for thinking about conflicts in moral judgments concerning AI. (shrink)

This book offers readers a pitch side seat to the ethics of fandom. Its accessible six chapters are aimed both at true sports fans whose conscience may be occasionally piqued by their pastime, and at those who are more certain of the moral hazards involved in following a team or sport. Why It's OK to Be a Sports Fan wrestles with a range of arguments against fandom and counters with its own arguments on why being a fan is very often (...) a good thing. It looks at the ethical issues fans face, from the violent or racist behavior of those in the stands, to players' infamous misdeeds, to owners debasing their own clubs. In response to these moral risks, the book argues that by being critical fans, followers of a team or individual can reap the benefits of fandom while avoiding many of the ethical pitfalls. The authors show the value in deeply loving a team, but also how a condition of this value is recognizing that the love of a fan comes with real limits and responsibilities. Key Features Provides an accessible introduction to a key area of the philosophy of sport Closely looks at some of the salient ethical concerns around sports fandom Proposes that the value of community in partisan fandom should not be underestimated as a key feature of the good life Examines how the same emotions and environments that can lead to violence are identical to those that lead to virtuous loyalty Argues for a fan's responsibility in calling out violence or racist behavior from their fellow fans. (shrink)