Here we review and discuss the link between regeneration capacity and tumor suppression comparing mammals (embryos versus adults) with highly regenerative vertebrates. Similar to mammal embryo morphogenesis, in amphibians (essentially newts and salamanders) the reparative process relies on a precise molecular and cellular machinery capable of sensing abnormal signals and actively reprograming or eliminating them. As the embryo's evil twin, tumor also retains common functional attributes. The immune system plays a pivotal role in maintaining a physiological balance to provide surveillance (...) against tumor initiation or to support its initiation and progression. We speculate that susceptibility to cancer development in adult mammals may be determined by the loss of an advanced regenerative capability during evolution and believe that gaining mechanistic insights into how regenerative capacity linked to tumor suppression is postnatally lost in mammals might illuminate an as yet unrecognized route to cancer treatment. (shrink)

本书分上下册,主要内容包括格言联壁,交友论,小窗幽记,安得长者言,菜根潭,围炉夜话,六事箴言,居官格言三十三条.

本书共分九章,内容包括:儒家概说、儒家追求的理想境界、内与外的和谐统一、家庭的和谐、人与人的和谐、人与社会的和谐等。.

volume 1. Zou xiang xin xue de jue wu zhi lu -- volume 2. Wen tao wu lüe de xin xue zong shi -- volume 3. Liang zhi xin xue de ren wen qing huai.

This paper discusses the philosophy of Zhu Xi, "a sub-Shu" concept, and that "a sub-Shu," Zhu Xi's philosophy in the concept of moral ethics, metaphysics, cosmology and so many different face. By "a sub-Shu," Zhu Xi's view, ethics has its objective basis for its endless from the Heaven. And this seems to be constructed for the contemporary world, to provide some contribution to the work ethic.

A new method of multiattribute decision making is proposed based on the max-min and min-max gray association degree. The gray association coefficients between the alternative, positive ideal solution and negative ideal solution are defined. Here, we construct a bi-objective programming model that maximizes the minimum gray association degree and minimizes the maximum gray association degree simultaneously. By using the linear weighted summation method, the bi-objective programming model is transformed into a linear programming model. Thus, we can obtain the weight vector (...) of attributes by solving the linear programming model. The ranking order of alternatives is generated according to the relative closeness. A numerical example is examined to demonstrate the applicability and implementation process of the decision method proposed in this paper. (shrink)

Dans la Chine de la fin du XVIIe siècle, les missionnaires jésuites français ont importé de Paris à Pékin une méthode de recherche scientifique typiquement française et aussi typiquement académique. Ce début prometteur a subi un infléchissement négatif dans le développement ultérieur des ambitions de la mission dans le champ des activités scientifiques del' Ancien Régime. On analyse ici les différences substantielles qui caractérisent la mission scientifique française jésuite à la fin du XVIIe siècle et au siècle suivant. À travers (...) une étude des éditions parisiennes de la production scientifique française jésuite en provenance de Chine, les Observations (1688, 1692, 1729), est expliqué le déclin de la mission scientifique française jésuite par la dissolution de ses liens avec l'Académie des sciences et par ses difficultés à construire et à maintenir une vision collective et une identité de corps dans l'analyse des phénomènes naturels. (shrink)

The effect of emotion on memory often leads to the trade-off: enhanced memory for emotional items comes at the cost of memory for background information. Although this effect is usually attributed...

The objective of this study is to investigate the effects of emotional labor on job performance and satisfaction, as well as to examine the mediating effect of sleep problems and the moderating effects of personality traits. A time-lagged study was conducted on 864 health professionals. Scales for emotional labor, sleep, personality traits, and job satisfaction were used and job performance data was obtained from records maintained by human resources. Structural equation modeling was performed to investigate the relations. Sleep problems only (...) partially mediated the relationship between surface acting and job satisfaction but completely mediated the relationship between surface acting and job performance. Several personality traits were shown to moderate the relationship between surface acting and sleep problems. The effects were stronger for people with low agreeableness and high neuroticism. The relationship between high levels of deep acting and low levels of sleep problems was more pronounced in individuals with low extraversion. Supervisors should be conscious of emotional labor in the work context and provide necessary deep acting training to facilitate emotional regulation. (shrink)

Previous research has explored how emotional valence affected face-context associative memory, while little is known about how arousing stimuli that share the same valence but differ in emotionality are bound together and retained in memory. In this study, we manipulated the emotional similarity between the target face and the face associated with the context emotion, and examined the effect of emotional similarity of negative emotion on face-context associative memory. Our results showed that the greater the emotional similarity between the faces, (...) the better the face memory and face-context associative memory were. These findings suggest that the processing of facial expression and its associated context may benefit from taking into account the emotional similarity between the faces. (shrink)

Although festival tourism is an excellent fertile ground for improving individual emotions, few studies have been conducted on the influencing factors and formation mechanisms of festival tourists’ subjective well-being. To address the current research gap, this paper draws on Arnold’ s theory of emotion to examine a comprehensive formation model of tourists’ subjective well-being. The findings from 581 samples indicate that event design innovation, cultural innovation and aesthetic innovation of festival tourism are positive stimulus factors of tourists’ subjective well-being. Both (...) experience quality and perceived festival value mediate the effects of cultural innovation and aesthetic innovation on subjective well-being, yet have no mediating effect on the relationship between event design innovation and well-being. However, it can only be achieved when festival authenticity contributes to a positive moderating effect. This study provides new ideas for the collaborative advancement of innovative development and authentic inheritance in festival tourism destinations. (shrink)

The puzzle has played a significant role in Chinese culture since its formation. The Lo-shu and the Ba-gua, the most prominent number puzzle in ancient China, with its instinctual quest for universal order, has constructed a philosophical system that has incorporated human being as an integral part of nature. The system has exerted great influence on Chinese culture to this day. Because of its mysterious origin and magical evolution, the Ba-gua has been used to predict the fortune of both the (...) nation and the individual. The Chinese character-deconstructing puzzle has also functioned as a foreshadow of one’s fate. By analyzing the components of a character, written by the subject in a specific context, divination was made. In contrast to the solemn mission of the number puzzle, and the character-deconstructing puzzle, the wedding puzzle and the riddle are lighthearted, and intended to provoke humor, and to function pedagogically. A latecomer, once the mysteriousness of number and character has faded, the riddle is used to promote the intellectual development of children. The wedding puzzle has been popular among those who are illiterate and make analogy by using common occurrence to allude to taboo in the oral dialect. Since their illiteracy has excluded them from reading and writing, they are free to make puzzles in their own dialect without being limited by a reverence for the written character. (shrink)

BackgroundBreast cancer patients are at elevated risk of depression during treatment, thus provoking the chance of poor clinical outcomes. This retrospective cohort study aimed to investigate whether integrating Chinese herbal medicines citation into conventional cancer therapy could decrease the risk of depression in the long-term breast cancer survivors.MethodsA cohort of patients aged 20–70 years and with newly diagnosed breast cancer during 2000–2008 was identified from a nationwide claims database. In this study, we focused solely on survivors of breast cancer at (...) least1 year after diagnosis. After one-to-one matching for age, sex, and baseline comorbidities, breast cancer patients who received and did not receive CHM treatment were enrolled. The incidence rate and hazard ratio citation for depression between the two groups was estimated at the end of 2012. A Cox proportional hazard model was constructed to examine the impact of the CHM use on the risk of depression.ResultsDuring the study period, the incidence rate of depression was significantly lower in the treated cohort than in the untreated cohort [8.57 compared with 11.01 per 1,000 person-years citation], and the adjusted HR remained significant at 0.74 in a Cox proportional hazards regression model. The corresponding risk further decreasing to 43% among those using CHM for more than 1 year.ConclusionFinding from this investigation indicated that the lower risk of depression observed in breast cancer patients treated with CHM, suggesting that CHM treatment should be considered for disease management toward breast cancer. Yet, the optimal administered dose should be determined in further clinical trials. (shrink)

Background: Informed consent is essential for the ethical conduct of clinical research and is a culturally sensitive issue. But, a measurable Chinese version of the scale to evaluate the informed consent process has not yet been explored in the existing literature. Research objectives: This study aimed to develop and psychometrically test the Chinese version of the Informed Consent Process Scale. Research design: Back-translation was conducted to develop the Chinese version of the questionnaire. A cross-sectional survey was administered, after which an (...) exploratory factor analysis was conducted. Participants: We recruited a total of 375 participants who had experience in signing an informed consent form within the previous 3 years in Taiwan. Ethical considerations: This study was approved by two Institutional Review Boards and the autonomy of the participants was respected. Findings: The Chinese version of the Informed Consent Process Scale is composed of three factors with 23 items showing evidence of acceptable reliability and validity. Three major factors were extracted and labeled: Factor 1 – ‘Understanding of the research’, Factor 2 – ‘Trust and confidence’ and Factor 3 – ‘Doubt and uncertainty’. The three factors accounted for is 52.954 of the total variance with Cronbach’s α of.917. Discussion and conclusion: The finding corroborates previous studies showing that participants had too little understanding on the informed consent forms they signed and implied the need to clarify the critical points in clinical research. The psychometric results indicated good internal consistency and validity for this newly constructed instrument, and it was found worthy of conducting further testing and application. (shrink)

This study constructs a mechanism of the influence of Guanxi between boundary spanners on opportunistic behaviors in collaborative innovation projects based on the theory of reasoned action model. The study conducts a survey in the automobile industry in Changchun, Jilin Province, China, and analyzes the research data using the structural equation model. The findings show that Guanxi has a negative an significant influence on opportunistic behavior attitudes and subjective norms., Guanxi has the greater influence on subjective norms than attitudes. Then, (...) opportunistic behavior attitudes and subjective norms positively influence intentions. The influence of subjective norms is stronger. The attitudes and subjective norms of opportunistic behaviors also play mediation roles. Furthermore, opportunistic behavior intentions have a positive and significant influence on behaviors. In short, the study’s findings reveal a mechanism of Guanxi between boundary spanners influencing opportunistic behaviors of boundary spanners. It also provides a reference for corporate managers to govern opportunistic behaviors of collaborator while inhabiting opportunistic behaviors of their own boundary spanners. (shrink)

This study examined academic dishonesty (AD) of 586 Taiwanese graduate students, the relationship between students' AD and their perceptions of AD of their peers, and their judgments regarding the seriousness of AD. Results showed that female students were more critical of AD than their male counterparts were in the areas of fraudulence, plagiarism, and falsification. Male students demonstrated more awareness of peer involvement in AD in the area of falsification than did female students. Master's students confessed to greater involvement in (...) AD compared with the PhD students. Doctoral students were more judgmental with respect to unethical acts of fraudulence, plagiarism, and falsification. (shrink)

Around 1716, the French astronomer and academician Joseph-Nicolas Delisle took up a new project: the twinned topics of Chinese chronology and astronomy. Unable to access Chinese sources and not knowing any fellow savants who shared this particular interest, Delisle methodically made extracts and compiled data from the existing European literature. Among Delisle's papers at the Observatoire de Paris still exist the results of this research, including a list of the books he found relevant. This paper develops a close reading of (...) Delisle's notes from this period to stage his journey into a recondite arena of technical and textual analysis, and to examine the scholarly practices and generic conventions through which early modern European savants confronted the Chinese astronomical tradition. (shrink)

Resumo: No processo de desenvolvimento de longo prazo, a cultura tradicional chinesa gradualmente formou características próprias. Ela é conhecida por sua extensa e longa história, que, em certa medida, proporciona um bom ambiente para a sobrevivência e reprodução do povo chinês. A introdução da filosofia marxista na China desempenhou um papel importante no trabalho prático da construção revolucionária do país. Ao mesmo tempo, a comunidade acadêmica explora constantemente o terreno comum entre a filosofia marxista e a cultura tradicional chinesa. Na (...) nova era da construção socialista, é necessário ter uma compreensão aprofundada da cultura tradicional chinesa. A fim de levar a China a realizar o sonho chinês o mais rápido possível e o grande renascimento da nação chinesa, este artigo trata da integração da cultura tradicional chinesa e da filosofia marxista, explorando a nova evolução da sinicização da filosofia marxista no novo período histórico. (shrink)

Using Reidenbach and Robin's Multidimensional Ethics Scale, this study investigated the relationships between background variables and students' ethical evaluations, judgments, and behavioral intentions using 3 scenarios involving dilemmas related to academic dishonesty. The sample included 436 master's students and 142 doctoral students. The study found that the participants used a combination of ethical philosophies to make ethical decisions. The respondents judged improper citations more harshly than acts of inappropriate authorship or the falsification of data. The doctoral students generally considered behaviors (...) related to plagiarism and falsification to be more unethical than the master's students did, though no gender differences were found. (shrink)