This article describes a current view of the events that initiated the transition from the rich organic and inorganic chemistry of the primitive Earth to the earliest forms of life. It is a personal condensation of the basic ideas developed in the so‐called Göttingen school. Most of these will be found in the seminal paper of Eigen1 and the other sources cited. A detailed exposition is given by Küppers2.

This essay is an attempt to point up the gap between, on the one hand, the methods currently available to the biologist in the laboratory and, on the other, the kind of data that he or she would need in order to characterise genetically engineered proteins of topical biological interest in such a way as to make use of the techniques of protein engineering.

Gordon Kaufman's “constructive theology” can easily be taken out of context and misunderstood or misrepresented as a denial of God. It is too easily overlooked that in his approach everything is an imaginary construct given no immediate ontological status—the self, the world, and God are “products of the imagination.” This reflects an influence, not only of theories on linguistic and cultural relativism, but also of Kant's “ideas of pure reason.” Kaufman is explicit about this debt to Kant. But I argue (...) there are other aspects of Kant's legacy implicit in his method. These center around Kaufman's engagement with “observed patterns” in nature. With Paul Tillich's aid, I bring this neglected issue to the fore and argue that addressing it allows one to more readily capitalize upon the Kantian influence in Kaufman's method. This, in turn, encourages one to tap more deeply into the epistemic underpinnings of Kaufman's approach to the science–religion dialogue. (shrink)

The increasing use of Generative AI raises many ethical, philosophical, and legal issues. A key issue here is uncertainties about how different degrees of Generative AI assistance in the production of text impacts assessments of the human authorship of that text. To explore this issue, we developed an experimental mixed methods survey study (N = 602) asking participants to reflect on a scenario of a human author receiving assistance to write a short novel as part of a 3 (high, medium, (...) or low degrees of assistance) X 2 (human or AI assistant) factorial design. We found that, for a human author, the degree of assistance they receive matters for our assessments of their level of authorship, creatorship, and responsibility, but not what or who rendered that assistance, although it was more important to disclose human rather than AI assistance. However, in our assessments of the assisting agent, human assistants were viewed as warranting higher rates of authorship, creatorship, and responsibility, compared to AI assistants rendering the same level of support. These results help us to better understand emerging norms around collaborative human-AI generated text, with implications for other types of collaborative content creation. (shrink)

The authors argue that the time is ripe for national and corporate leaders to move consciously towards the development of global ethics. This papers presents a model of global ethics, a rationale for the development of global ethics, and the implications of the model for research and practice.

Does it make sense to say that certain evaluative outlooks and political ideologies are essentially negative or oppositional in structure? Intuitively, it seems so: there is a difference between outlooks and ideologies that are expressive of hatred, resentment, and contempt, on the one hand, and those expressive of more affirmative emotions. But drawing this distinction is more difficult than it seems. It requires that we find a way of maintaining the following claim, which I call Negative Orientation: although you claim (...) to value X, you are more accurately described as disvaluing Y. I argue that we cannot make sense of Negative Orientation at the level of evaluative judgments, for nothing about the etiology, content, or justification of evaluative judgments will support the Negative Orientation claim. But we can make sense of it by attending to the psychology of valuing. Using spiteful hatred as a paradigm case, I explain how certain outlooks and ideologies induce and sustain spiteful hatred in their adherents and thereby render the Negative Orientation claim true. (shrink)

Experimental philosophy of science gathers empirical data on how key scientific concepts are understood by particular scientific communities. In this paper we briefly describe two recent studies in experimental philosophy of biology, one investigating the concept of the gene, the other the concept of innateness. The use of experimental methods reveals facts about these concepts that would not be accessible using the traditional method of intuitions about possible cases. It also contributes to the study of conceptual change in science, which (...) we understand as the result of a form of conceptual ecology, in which concepts become adapted to specific epistemic niches. (shrink)

To several critics of the philosophical method of cases—Robert Cummins, Jonathan Weinberg and his colleagues, and Avner Baz—the fact that philosophical intuitions cannot be calibrated means that we cannot rule out the skeptical hypothesis that the outcome of our theorizing based on these intuitions is deeply distorted by our cognitive artifacts. Moreover, they take this hypothesis to license the negative conclusion that we are unable to have much of the armchair knowledge we typically attribute to ourselves when philosophizing based on (...) appeal to philosophical intuitions. This paper addresses this skeptical argument and shows how this negative conclusion can be resisted. (shrink)

Descartes has a Clarity First epistemology: (i) Clarity is a primitive (indefinable) phenomenal quality: the appearance of truth. (ii) Clarity is prior to other qualities: obscurity, confusion, distinctness – are defined in terms of clarity; epistemic goods – reason to assent, rational inclination to assent, reliability, and knowledge – are explained by clarity. (This is the first of two companion entries; the sequel is called, "Descartes's Method for Achieving Knowledge.").

This essay re-examines Adam Smith’s encounter with Jean-Jacques Rousseau. Against the grain of present scholarship it contends that when Smith read and reviewed Rousseau’s Second Discourse, he neither registered it as a particularly important challenge, nor was especially influenced by, or subsequently preoccupied with responding to, Rousseau. The case for this is made by examining the British context of Smith’s own intervention in his 1759 Theory of Moral Sentiments, where a proper appreciation of the roles of David Hume and Bernard (...) Mandeville in the formation of Smith’s thought pushes Rousseau firmly into the background. Realising this, however, forces us to re-consider our evaluations of Rousseau’s and Smith’s very different political visions. Given that questions of individual recognition, economic inequality, and political stability remain at the heart of today’s social challenges, the implications of this are not just historical but of direct contemporary import. (shrink)

According to Alasdair MacIntyre's influential account of practices, ‘teaching itself is not a practice, but a set of skills and habits put to the service of a variety of practices’ (MacIntyre and Dunne, 2002, p. 5). Various philosophers of education have responded to and critiqued MacIntyre's position, most notably in a Special Issue of the Journal of Philosophy of Education (Vol. 37.2, 2003). However, both in that Special Issue and since, this debate remains inconclusive. Much of this earlier discussion seems (...) to accept that teaching is a unique case in being a putative practice that does not fit readily into MacIntyre's account. In fact many supposed practices, including some nominated by MacIntyre himself, do not fit his account. A constructive critique of this account leads to a refurbished, broadly MacIntyrean account of practice. This will clarify the issue of whether teaching and a range of other activities are, indeed, practices. (shrink)

Nous proposons dans cet article des éléments nouveaux pour l’interprétation de la doctrine d’Héraclite, concernant en particulier le rôle de l’opposition des contraires en tant que générateur d’harmonie, mentionné dans les Fragments 8 et 51. Cette interprétation est basée sur l’outil conceptuel que constituent les matrices de concepts. Après avoir décrit les éléments fondamentaux qui régissent ces dernières, nous nous attachons à définir dans ce cadre conceptuel les notions d’opposition et de contraire, ainsi que d’harmonie. Cela permet de fournir une (...) interprétation ainsi qu’une justification pour la doctrine spécifique d’Héraclite, selon laquelle l’opposition des contraires est génératrice d’harmonie. (shrink)

We examine possible causal structures of experiments with entangled quantum objects. Previously, these structures have been obscured by assuming a misleading probabilistic analysis of quantum non locality as 'Outcome Dependence or Parameter Dependence' and by directly associating these correlations with influences. Here we try to overcome these shortcomings: we proceed from a recent stronger Bell argument, which provides an appropriate probabilistic description, and apply the rigorous methods of causal graph theory. Against the standard view that there is only an influence (...) between the measurement outcomes, we show that there must be an influence from one setting to its distant outcome: EPR correlations can only come about if one of the outcomes is a common effect of both settings. Our discussion makes explicit under which assumptions similar conclusions from information theoretic considerations can be interpreted causally. (shrink)

Sainsbury argued that exact extensions for predicates entails the unacceptable infinite tower of higher order vagueness so that exact extensions must be rejected. I offer a second argument: The exact extensions arise when semantic values are assumed to be (exact) properties. But no assignment of unique properties to predicates could arise from any real-world finite basis. How, then, is talk of properties as semantic values to be understood? We distinguish the precise compositional rules of semantics from the operation of messy, (...) imprecise rules at the word/world interface for applicability of minimal predicates. When such application is sufficiently clear it is idealized as property instantiation and semantic composition proceeds in familiar ways. These imprecise rules for application of minimal predicates provide the proper locus for study of vagueness. The conclusions thus far apply to show that higher order vagueness is not forced and that classical logic can generally be retained. I discuss implications for the sorites paradox. Abandoning properties entails abandoning simple correspondence truth understood as Pa is true just in case a has the property signified by P. As an alternative I outline a pragmatist approach to truth, the spirit of which is conveyed by the slogan, “To be true enough is to work well enough.”. (shrink)

Ethnophilosophy is widely regarded as a disreputable orientation in African philosophy. For example, critics of ethnophilosophy think of it as a ‘defective philosophy’, a ‘semi-anthropological paraphrase’, a merely ‘implicit philosophy ’, a ‘crazed language’ and so on. Although these negative portrayals were made in the 1980s and 1990s (roughly, 1981–1997), and some of these critics softened their position with time, they persist in the thoughts of some contemporary African philosophers. This is visible in the rather inarticulate unease about ethnophilosophy in (...) many quarters today, witnessed in the characteristic disposition of some African philosophers to distance themselves from the works of Placide Tempels, John S. Mbiti, Léopold Sédar Senghor and Alexis Kagame, and in the talk of a post-ethnophilosophy among some contemporary African philosophers rooted in the belief about the inadequacy of ethnophilosophy. Call those who today still think of ethnophilosophy in this fashion the ethnophilosophy holdouts. The aim of this paper is to give reasons to think that the position of the ethnophilosophy holdouts is not tenable. More positively, I defend a thesis that makes a claim about the positive status of ethnophilosophy as a philosophical orientation. (shrink)

Gilbertson, Savulescu, Oakley and Wilkinson propose extending the availability of terminal sedation (TS) to patients with intractable pain and/or suffering who are expected to live more than 2 weeks (hence the designation of extended TS (ETS)) and to patients whose values are known but who do not have decision-making capacity.1 Their plan is worthy of serious consideration: it is, after all, based on the fundamental and well-recognised medical ethical values of patient autonomy and beneficence. But, even when restricted to jurisdictions (...) that allow assisted dying, the ETS proposal raises three important issues. When the authors speak of ‘assisted dying’ and of ‘Voluntary Assisted Dying (VAS)’, they refer specifically to the laws in Australia and similar ones in New Zealand, the Netherlands, Belgium, Luxembourg, Switzerland, Spain and Canada that permit clinicians either to provide patients with lethal medications for self-administration (formerly called physician-assisted suicide) or to administer lethal medications themselves (voluntary euthanasia). First, the authors distinguish—as do many patients and the public—between sedation to unconsciousness and death. Indeed, as the authors point out, the difference seems obvious: unconsciousness can be reversed, death cannot. Yet in the case of TS, this may be …. (shrink)

Antidepressant medication and evidence-based psychotherapy have largely equivalent efficacy in the management of the common, less severe grades of depression. As a result, several national guidelines recommend that either can be used in the treatment of this disorder. Psychotherapy, however, differs in that it assists insight into how the depressed person appraises and manages the stressors that frequently trigger depressive episodes. I argue that the self-knowledge achieved through psychotherapy has moral value in that it promotes the autonomy of stressor-related decisions. (...) I further argue that such an effect comprises a compelling moral reason for doctors to see evidence-based psychotherapy not as merely optional, but as a necessary treatment for their patients with depression. (shrink)

ABSTRACT This paper is a case study in public health ethics. It considers whether there is a basis in ethics for political action by health professionals and their associations in response to inhumane treatment. The issue arises from Australia's treatment of asylum seekers and the charge that this treatment has been both immoral and inhumane. This judgement raises several questions of broader significance in bioethics and of significance to the emerging field of public health ethics. These questions relate to the (...) role of health professionals in response to inhumane treatment of people in their charge; to the discipline of public health in light of a growing recognition of its ethical basis; and the role of public health and bioethical associations in response to ethical issues arising in a political context. It is argued that, in serious cases of humanitarian and human rights abuses affecting health and well‐being, there is a case for political action by health professionals, academic and professional institutions, and associations of public health and ethics. (shrink)

Epistemic Analysis, as I conceive of it, is concerned with the analysis of knowledge. The precincts of my concern have, however, been determined by the ...

This paper considers traditional debates and position regarding time and the future in relation to Einstein's physics of space-time.

In lieu of an abstract, here is a brief excerpt of the content:The Myth of Renaissance Atheism and the French Tradition of Free Thought PAUL OSKAR KRISTELLER WITHIN THE VAST AND COMPLEX area of Renaissance philosophy, the thought of Pietro Pomponazzi and of the entire Italian school of Aristotelianism of which he is the best known representative has not yet been studied in all its aspects? Apart from a number of recent studies, mostly Italian or American, there is an (...) important body of French studies on the subject that are distinguished by their ample documentation and by a general and consistent tendency of interpretation and that have exercised a predominant influence in this field of research. The fountainhead of this French scholarship on Renaissance Aristotelianism is E. Renan's book on Averroes and Averroism, a remarkable achievement for its time, and a classical study still worth reading after more than a hundred years have passed since it was first published. 2 It is generally recognized that Renan's conclusions about Averroes himself and about the Latin Averroism of the thirteenth century have been superseded by the later studies of P. Mandonnet and others? It is less well known that, for the This paper was read many years ago at the New England Conference on the Renaissance at Brown University, and at the Universit~ de Fribourg. It was published as "El Mito del Ateismo Renacentista y la Tradici6n Francesa del Librepensamiento" in Notas y Estudios de Filoso]la, ed. Prof. Juan Adolfo Vazquez, IV, 13 (Tucums Argentina, 1953), pp. 1-14. The present version has been only slightly revised, and I hope to return to the subject on a later occasion. Among recent studies, I should like to mention G. Spini, Ricerca dei l.,ibertini (Rome, 1950) and D. C. Allen Doubt's Boundless Sea (Baltimore, 1964), who follow on the whole the view criticized in this paper, and L. Febvre, Le problhme del lincroyance au XVI ~ si~cle (Paris, 1947) and R. H. Popkin, "Skepticism and the Counter-Reformation in France," Archiv ]iir Re]ormationsgeschichte LI (1960), 58-88, who seem to concur with my view. See also a paper by Popkin~"Skepticism, Theology and the Scientific Method in the 17th century," in Problem8 in the Phdosophy o] Science, ed. I. Lakatos and A. Musgrave (Amsterdam: North Holland Publishing Co., 1968). 1See now B. Nardi, Saggi sull'Aristotelismo Padovano dal secolo XIV al XVI (Florence, 1958) and Studi su Pietro Pomponazzi (Florence, 1965); J. H. Randall, The School o] Padua and the Emergence o] Modern Science (Padua, 1961); P. Pomponazzi, De ]ato, de libero arbitrio et de praedestinatione, ed. R. Lemay (Lugano, 1957); Tractatus de immortalitate animae, ed. G. Morra (Bologna, 1954); Corsi inediLi dell'insegnamento padovano I, Super libello de substantia orbis et quaestiones quattuor, ed. A. Poppi (Padua, 1966); P. O. Kristeller, "A New Manuscript Source for Pomponazzi's Theory of the Soul from his Paduan Period," Revue Internationale de Philosophie, V: 2 (16, 1951), 144-157,and "Two Unpublished Questions on the Soul by Pietro Pomponazzi," Medievalia et Humanistica, IX (1955), 76-101,and X (1956), 151. See also: G. Di Napoli, L'immortalit~ dell'anima nel Rinascimento (Turin, 1963); E. GiN ~L,, 3 son, Autour de Pomponazzi, Archives d histoire doctrinale et litt~raire du Moyen Age, c,,,, LXIII (1961, pub. 1962), 163-279and Laffaire de limmortalit~ de ls ~ Venise au debut 9,, du XVI si~cle, in Umanesimo europeo e umanesimo veneziano, ed. V. Branca (Florence, 1963), 31-61. Relevant are also the unpublished Columbia dissertations by William F. Edwards (on Zabarella), Martin Pine (on Pomponazzi and his critics) and Edward Mahoney (on Agostino Nifo). Averro$s et l Averro~me (Paris, 1852). 8Siger de Brabant et l'averroisme latin au XIII ~ si$cle (2nd ed.; Paris, 1908-11); F. Van [233] 234 HISTORY OF PHILOSOPHY history of Italian Aristotelianism after the thirteenth century, this book by Renan has never been completely superseded, but still constitutes the general basis for a large part of the later literature on the subject. Recent studies have added numerous details, but have failed to correct numerous errors and misconceptions. The main thesis of Renan's book on which we shall focus our attention in this paper is the following: Paduan Averroism... (shrink)

Since 1790, the term Naturwissenschaften occurs in the lecture lists of the University of Jena published in the Allgemeine Literatur‐Zeitung of Jena. Naturwissenschaften is used as a title for lectures previously listed under the headings of Philosophie or Naturgeschichte. The introduction of the concept of Naturwissenschaften is interesting for several reasons: Firstly, at that time it is not the usual label in this context, and one therefore has to ask whether it already implies the connotations that are associated with the (...) modern concept of Naturwissenschaften, i. e. science in the modern sense. Secondly, the lecture lists of the University of Jena give insight into the various changes in the established ordering scheme for academic lectures that lead to the introduction of the term Naturwissenschaften, thus contributing to a better understanding of both the history of this concept and of the development of the university faculties as we know them. A close look at the concept of Naturwissenschaften as it was used around 1800 may, thirdly, help to understand the use made of this concept in philosophy, especially in the philosophy of nature of this period. (shrink)

The paper examines the status of conscious presentation with regard to mental content and intentional states. I argue that conscious presentation of mental content should be viewed on the model of a secondary quality, as a subjectiveeffect of the microstructure of an underlying brain state. The brain state is in turn viewed as the instantiation of an abstract computational state, with the result that introspectively accessible content is interpreted as a presentation of the associated computational state realized by the brain. (...) However, if the relation between consciousness and representational content is construed in this manner, then conscious presentation does not provide an adequate foundation for the claim that human mental states areintrinsically intentional. On this model, I argue that functionalism is able to account for (non-intrinsic) intentionality, but not for consciousness, which has implications for the computational paradigm, as well as for Searle's Chinese room thought experiment. (shrink)

Shaun Nichols (this issue) correctly points out that current theories of the development of mindreading say nothing about children's intuitions concerning indeterminist choice. That is, there are numerous theories of how children make sense of belief, desire, and action, but none that appeal to any notion of free will. Nichols suggests two alternatives for why this is the case. It could either be (a) an --outrageous oversight-- on the part of developmental psychologists or (b) a principled omission, reflecting a consensus (...) that the notion of indeterminist choice is absent from children's mindreading processes. Nichols charitably favors the sec- ond alternative. (shrink)

Phenomenal character is the what-it's-likeness of subjective experience. I develop an ontology of phenomenal feel as process. My being in some phenomenal state R is the process of my instantiating R’s neurological correlate. The ontology explains why we have asymmetric epistemic access to phenomenal characters: the ontological ground for the subjective or first-personal stance is different from the ontological ground for the objective or third-personal stance. I end by situating my account in debates about physicalism.

The Southern Journal of Philosophy, Volume 60, Issue 2, Page 154-172, June 2022.

Quite remarkably, Friedrich Wilhelm Joseph Schelling uses the notion of “drive” in analysing important cognitive achievements: An important instance of this attitude can be found in his characterizing Kant as a philosopher who operates in the basis of instincts. His key argument in adopting “drives” as key to the cognitive faculties of humans derives from the conviction that cognitive endeavours need to be open and directed towards grasping reality not in individual items, but as a totality. He arrives, in employing (...) these terms, at an understanding of science, and of cognition in general, as an open, future-directed, and dynamic process. This chapter presents an overview of Schelling’s usage of “drive”-related terms, discusses his rather detailed description of the mechanics of drives within the structure of human faculties, and draws some conclusions as to Schelling’s understanding of “science” and the dynamics of science. (shrink)

This paper critically examines the prevalence of age comparison studies in developmental psychology. It argues that many such studies, which aim to determine when children acquire adult-like abilities, lack clear theoretical justification. The critique is framed within broader discussions of research priorities in psychology, drawing parallels to past trends in neuroscience where initial fascination with brain localization gave way to more theoretically driven research. Questioning the value of studies motivated primarily by publication rather than theoretical advancement, the paper advocates for (...) a shift towards research that addresses fundamental questions about developmental mechanisms. Implications for research design and the future direction of developmental psychology are discussed. (shrink)

David Papineau (2003; 2005) has discussed the relationship between social learning and the family of postulated evolutionary processes that includes ‘organic selection’, ‘coincident selection’, ‘autonomisation’, ‘the Baldwin effect’ and ‘genetic assimilation’. In all these processes a trait which initially develops in the members of a population as a result of some interaction with the environment comes to develop without that interaction in their descendants. It is uncontroversial that the development of an identical phenotypic trait might depend on an interaction with (...) the environment in one population and not in another. For example, some species of passerine songbirds require exposure to species-typical songs in order to reproduce those songs whilst others do not. Hence we can envisage a species beginning with one type of developmental pathway and evolving the other type. If, however, the successive evolution of these two developmental pathways were a mere coincidence, selection first favoring the ability to acquire the trait and later, quite independently, favoring the ability to develop it autonomously, then this would not be a distinctive kind of evolutionary process, but merely two standard instances of natural selection. George Gaylord Simpson pointed this out in the paper that gave us the term ‘Baldwin effect’ (Simpson, 1953). The real interest of the Baldwin effect and its relatives lies in the mechanisms which might link the evolution of the two developmental pathways, so that acquiring the trait through interaction with the environment makes it more likely that later generations will evolve the ability to acquire the same trait without that interaction. (shrink)

Taking the semantic values of predicates to be precise properties leaves no room for predicate vagueness. I suggest instead understanding talk of properties as used in semantics as idealized placeholders for the imprecise results of navigating the word/world interface. Basic predications result by applying imprecise informal rules of word use, and it is in the imprecision of these rules that vagueness arises. The idealized property-placeholders then function to separate the messy process of navigating the word/world interface from the exact rules (...) of semantic composition. This scheme applies a methodology of problem separation that is well known in the physical sciences. (shrink)

Alongside his groundbreaking work in logic, Bernard Bolzano (1781?1848) made important contributions to ontology, notably with his theory of collections. Recent work has done much to elucidate Bolzano's conceptions, but his notion of a sum has proved stubbornly resistant to complete understanding. This paper offers a new interpretation of Bolzano's concept of a sum. I argue that, although Bolzano's presentation is defective, his conception is unexceptionable, and has important applications, notably in his work on the foundations of arithmetic.

A leaf falls to the ground, wafting lazily on the afternoon breeze. Clouds move across the sky, and birds sing. Are these events governed by universal laws of nature, laws that apply everywhere without exception, subsuming events such as the falling of the leaf, the movement of the clouds and the singing of the birds? Are such laws part of a small set of fundamental laws, or descended from such a set, which govern everything there is in the world?