In David Lodge's novel Changing Places, the protagonist Morris Zapp recalls his plan for a series of commentaries examining Jane Austen's novels under every possible rubric, from the historical to the structuralist, the mythical to the Marxist--all in order so to monopolize interpretation as to exhaust it altogether. I take it that Michael Krausz would find Zapp's ambition both unpalatable and impracticable, although he does not actually rule it out of court. Krausz's topic is interpretive ideals, and (...) his target is the "singularist" who holds that any object of interpretation is in principle open to only one "right" interpretation. To this view, Krausz opposes his own "multiplism," which claims that "the range of ideally admissible interpretations in some practices should be multiple". (shrink)

This book addresses critical issues in normative ethical theory. Every such theory must contain not only a theory of motivation but also a theory of value, and the link that is often forged between what is valuable and what would be right is human welfare or well-being. This topic is a subject of considerable controversy in contemporary ethics, not least because of the current reconsideration of utilitarianism. Indeed, there is as much disagreement about the nature of value and its relationship (...) to welfare and morality, as there is about the substantive content of normative ethical theories. The essays in this collection, all written by a distinguished team of moral philosophers, provide an overview, analysis and an attempted resolution of those controversies. They constitute a rigorous account of the relationships among value, welfare and morality. (shrink)

This is a comprehensive study of the varying conceptions of the human subject in the Western intellectual tradition. Although informed by an anthropological perspective, the author draws on material from all the major intellectual disciplines that have contributed to this tradition and offers biographical and theoretical vignettes of all the major Western scholars. By scrutinizing the classical texts of the Western tradition, he succeeds in delineating the differing conceptions of the human individual which emerge from these writings, and gives a (...) guide to the most important ideas in Western cultural traditions. (shrink)

Some philosophers have recently complained that moral theories almost always portray the distresses of ordinary people in moral predicaments as irrational. In the name of having a minimally realistic picture of ethical thought, these philosophers argue that accounts of morality must allow for strong moral dilemmas, choices involving mutually exclusive all-things-considered requirements or jointly exhaustive all-things-considered prohibitions. In this dissertation I clarify and reject several versions of this argument, which I call the argument from experience. ;In chapters one and two (...) I define strong moral dilemmas as essentially involving conflicts of moral reasons, and reject as premature attempts to reduce questions about strong dilemmas to questions about deontic logic. I accept the goal of representing ordinary experience faithfully, and ask whether a theory will necessarily distort that experience if it employs interpretations of 'ought' and 'prohibited' in ways guaranteeing a priori that there are no strong dilemmas. ;The argument from experience claims that people can have a justifiably high degree of confidence that they are in strong moral dilemmas, and in chapter three I question whether people ever have the needed sorts of confidence about the limits of their abilities, the precise location of their wrongdoing, or the futility of continued moral deliberation. ;In chapter four I reject specific arguments based on regret and guilt. The tendency to feel unavoidable agent-regret or guilt allegedly shows that the agent sees the choice as a strong dilemma, and the appropriateness of such distresses allegedly shows that the agent's way of seeing things is rational. I reply that someone can feel agent-regret without endorsing any moral judgment involving 'ought' or 'prohibited', and that guilt is never unavoidably appropriate. ;In chapter five I trace the failure of the argument from experience to the presence in ordinary thought of a notion of blame which is both conceptually guaranteed always to be avoidable and regarded as an infallible indicator of moral requirement and prohibition. I am led to wonder, finally, why this notion of blame should play a privileged role in philosophical pictures of morality. (shrink)

The discovery of the first intracellular substrate for insulin, IRS‐1, redirected the field of diabetes research and has led to many important advances in our understanding of insulin action. Detailed analysis of IRS‐1 demonstrates structure/function relationships for this modular docking molecule, including mechanisms of substrate recognition and signal propagation. Recent work has also identified other structurally similar molecules, including IRS‐2, the Drosophila protein, DOS, and the Grb2‐binding protein, Gab1, suggesting that this intracellular signalling strategy is conserved evolutionarily and is utilized (...) by an expanding number of receptor systems. In fact, IRS‐1 itself has been shown to be important in other growth factor and cytokine signalling systems, including growth hormone and several interleukins. Analysis of mice lacking IRS‐1 confirms an important physiological role for this protein in glucose metabolism and general cell growth in the intact animal. Disregulation of the signalling pathways integrated by the IRS proteins may contribute to the pathophysiology of non‐insulin‐dependent diabetes mellitus or other diseases. (shrink)

A study of habit and other unconscious backgrounds of action shows how shapes of spiritual life in Hegel's Phenomenology of Spirit each imply correlative senses of lived time. The very form of time thus gives spirit a sensuous encounter with its own concept. The point that conceptual content is manifest in the sensuous form of time is key to an interpretation of Hegel's infamous and puzzling remarks about time and the concept in ``absolute knowing.'' The article also shows how Hegel's (...) Phenomenology connects with current discussions of lived time, habit, and, via discussion of Wallace's Infinite Jest, addiction. (shrink)

Available in English for the first time, _Hegel and the Freedom of Moderns_ revives discussion of the major political and philosophical tenets underlying contemporary liberalism through a revolutionary interpretation of G. W. F. Hegel’s thought. Domenico Losurdo,_ _one of the world’s leading Hegelians, reveals that the philosopher was fully engaged with the political controversies of his time. In so doing, he shows how the issues addressed by Hegel in the nineteenth century resonate with many of the central political concerns of (...) today, among them questions of community, nation, liberalism, and freedom. Based on an examination of Hegel’s entire corpus—including manuscripts, lecture notes, different versions of texts, and letters—Losurdo locates the philosopher’s works within the historical contexts and political situations in which they were composed. _Hegel and the Freedom of Moderns_ persuasively argues that the tug of war between “conservative” and “liberal” interpretations of Hegel has obscured and distorted the most important aspects of his political thought. Losurdo unravels this misleading dualism and provides an illuminating discussion of the relation between Hegel’s political philosophy and the thinking of Karl Marx and Friedrich Engels. He also discusses Hegel’s ideas in relation to the pertinent writings of other major figures of modern political philosophy such as Jean-Jacques Rousseau, John Locke, Edmund Burke, John Stuart Mill, Jeremy Bentham, Karl Popper, Norberto Bobbio, and Friedrich Hayek. (shrink)

This book expands the conversation on moral injury to include a more formal role for society in it. The author utilizes an interdisciplinary practical theology combining liberation theologies and cultural studies to interrogate how dominate ideologies can complicate moral injury reintegration among veterans.

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