Many scientific disciplines rely on the construction and use of models: biomedical sciences are no exception. This PhD thesis addresses several aspects of the practice of scientific modeling. First, I discuss the nature of modeling as such, proposing a novel, complementary account of scientific modeling which I term the experimentation-driven modeling account and which drives the construction of mechanistic models in many fields of biological and biomedical research, such as cancer immunology. Second, I scrutinize an objection to the mechanistic account (...) of explanation according to which the account fails to accommodate the common practice of idealizing difference-making factors. I argue that this objection ultimately fails because it is riddled with a number of conceptual inconsistencies. Third, I analyze the roles of similarity judgments in some fields of cancer research which employ a variety of mouse models to learn about the disease mechanisms, arguing that by appreciating the epistemic complexities it is possible to shed new light on more general philosophical debates regarding scientific representation. Fourth, mechanisms can also be studied using more theoretical apparatus in the form of simulations. I investigate an example of an agent-based model used to model the outbreak of SARS-CoV-2... (shrink)

Este trabajo se propone estudiar las características de los paralogismos de composición y división (Retórica II 24.II, 1401a), de la consecuencia (Retórica II 24.VI, 1401b20-30) y de la causa aparente (Retórica II 24.VII, 1401b30-34), de modo de analizar si Eurípides los utiliza en el agón de Andrómaca de los versos 577 a 746 This paper intends to study the characteristics of paralogisms due to composition and division (Rhetoric II 24.II, 1401a), due to consequent (Rhetoric II 24.VI, 1401b20-30), and due to (...) false cause (Rhetoric II 24.VII, 1401b30-34), in order to analyze if Euripides uses them in the agon in Andromache (577-746). (shrink)

These six essays present one of the most significant stages in the development of Buber's philosophical thought and particularly his philosophical anthropology. This edition includes an appendix consisting of an interesting dialogue between Buber and psychologist Carl R. Rogers.

_How to Make Our Signs Clear_ focuses on selected aspects of Peirce´s philosophy and semiotic, possible historical connections of his work and contemporary challenges to Peirce’s semiotic theories.

According to Roberts, self-experimentation is a viable tool for idea generation in the behavioral sciences. Here we discuss some limitations of this assertion, as well as particular design and data-analytic shortcomings of his experiments.

Plato's rhetorical gesture invoking a 'quarrel' between philosophy and poetry points to a deep problem in our conception of rational discourse, often obscured or displaced in the history of philosophy's relations with imaginative literature, especially with respect to analytic philosophy in the first half of the twentieth century. Recent developments have helped focus attention on the overlap between philosophy and literature, which the contemporary retreat from philosophy's 'narrative turn' does little to undermine. Further work in the philosophy of language, the (...) logic of the imagination, and the relations between dialectic and rhetoric promise to throw light on that ancient problem. (shrink)

Growing interest has been shown toward humanism in the 21st century after decades of critique and rejection. Posthumanism and transhumanism have redefined the topic primarily through developments in technology and by focusing on relations of interconnectedness between humans and the environment. A different concern with ‘being human’ can be found in the writings of Zygmunt Bauman and Ernst Bloch. The leitmotif of Bauman’s sociology and of Bloch’s utopian philosophy is their assertion that humans have the distinct capacity to transcend necessity (...) and inevitability. Their works share the concern for a good society that would ameliorate social fragmentation and disintegration. Following this, the article seeks to theorize the meaning of humanism in the contemporary era. Taking up Bauman’s notion of interregnum, the article will argue that the contemporary importance of humanism is social in the sense of redeeming the currently casualized human condition, i.e. diminished life-chances, inequality and alienation. Interregnum marks a historical epoch where the old order has decayed, but the new one is not yet present. In interregnum, or in what Bloch calls Mischzeit, humanism is about a human being-in-the-world which contains the possibility to do better. (shrink)

Među mnoštvom dimenzija kolektivnog identiteta, ovaj rad istražuje identitet kao retorički alat. Identitetska oznaka je upravo primjer pragmatične učinkovitosti. Kako bi se objasnila ta moć, izložit će se hipotetički model identitetskih kategorija. Njegovi konstitutivni moduli oblikuju četiri osnovne dimenzije: pozicija, deindividualizacija, isključenje i kognitivna zaštita. Tako ocrtan narativni identitet postaje ekvivalentan neformalnoj ideologiji . Kao konstitutivna retorika , narativna konstrukcija identiteta pretvara autoreferencijalnu tautologiju u strategije diskriminacije, pročišćenja i istrebljenja nositelja drugosti. Masovna uništenja u prošlom stoljeću – totalitarizam, kolonijalizam, etno-nacionalizam (...) – proizvodi su identitetske paradigme. (shrink)

In “Principled Compromise and the Abortion Controversy” Simon C. May argues that we do not have a principled moral reason to compromise. While I seek to understand how more precisely we are to understand this suggestion, I also object to it: I argue that we have a principled moral reason to accept democratic decisions that we disagree with, and that this can only be so if disagreement can change what the all things considered right political position is. But if this (...) is so, then also a principled moral reason to compromise is possible. I suggest that there is a class of procedures, including compromise, voting, expert delegation, and coin flip, such that when we disagree about what justice requires, we have a principled moral reason to engage in one of these procedures. (shrink)

The son of Nahum Goldmann, who was the founder of the World Jewish Congress, Guido Goldman was one of the most distinguished protagonists of the reintegration of Germany into the international community after the defeat of Nazism in 1945. Later he helped establish the German Marshall Fund and created Harvard University's Center for European Studies as one of the pre-eminent research institutes and meeting places in the world for scholars, graduate students, prominent politicians, and artists. His large network of friends (...) and interlocutors included Willy Brandt and Helmut Kohl, Henry Kissinger and Ronald Reagan, Harry Belafonte and Marlene Dietrich. His generous philanthropy extended to the preservation of non-Western cultures threatened by extinction, such as the IKAT project through which he revived the unique ancient textile arts of Central Asia. All this comes alive in Martin Klingst's careful reconstruction of Goldman's life. (shrink)

From overcrowded lifeboats to the censor's pen, Martin Cohen's stimulating and amusing dilemmas will have you scratching your head and laughing out loud in equal measure.

Taking a fresh view on Wittgenstein's apparent ethical skepticism, many contributions to this volume explore the reach of what can be said in ethical terms, while others provide critical discussions of what is being said in various fields of applied ethics and political philosophy under real-world power relations. This volume collects invited contributions from the 35th International Wittgenstein Symposium 2012 in Kirchberg am Wechsel, Austria.

In everyday life, assumptions about our peers' as well as our own personality shape social interactions. We investigated whether self-rated personality and inferences drawn from partners' faces influence economic decisions. Participants (N= 285) played the trust game in the role of the trustor as well as the ultimatum game in the role of the proposer and interacted with trustees and receivers represented by prototypical personality faces. Participants also evaluated both their own traits and the personality of the faces. In the (...) trust game, trustees represented by faces rated higher on agreeableness yielded higher transferred amounts. This effect was more pronounced for trustors low on dispositional trust, whereas trustors high on dispositional trust did not relate their decisions to the faces. Trustees represented by faces rated higher on conscientiousness yielded higher transferred amounts only for trustors high on dispositional anxiety. In the ultimatum game, receivers represented by faces rated higher on conscientiousness yielded lower offers only for proposers high on dispositional assertiveness. These results extend previous findings on the inferences drawn from facial features and the influence of personality on decision making. They highlight the importance of considering the personality of both interaction partner, as well as potential interactions of players' traits. (shrink)

This chapter contains section titled: “Exposition of the Task of a Preparatory Analysis of Dasein”.

Although science and law employ different methods to gather and weigh evidence, their conclusions are remarkably convergent with regard to the effect that workplace stress has on the health of employees. Science, using the language of probability, affirms that certain stressors predict adverse health outcomes such as disabling anxiety and depression, cardiovascular disease, certain types of injury, and a variety of immune system disorders. Law, using the language of reasonable foreseeability, affirms that these adverse outcomes are predictable under certain conditions, (...) typically defined in relation to what a reasonable person should know. Society is arguably in a position to establish standards for the abatement of certain types of workplace stress. As part of this process, we need to conceptualize an ideal form of conduct that exemplifies the standards to which both law and science urge us to aspire. For this purpose, the concept of the neighbor at work is proposed. (shrink)

This paper aims at a conceptual clarification of some of the mechanisms that are involved when human selves are made in interactions with each other. Four such broad mechanisms are distinguished: socialisation, classification of self and others, the deference-emotion system, and the attribution and manipulation of the status of the responsible agent. The first two mechanisms are modelled with simple mechanical machines like clocks and signalling devices. Regarding the status of the responsible agent, the paper offers a proposal as to (...) why we have conflicting intuitions about freedom of the will. (shrink)

This text contains 54 of Martin Gardner's most searching and challenging essays, spanning nearly six decades. Issues tackled range from the apparent inexplicability of quantum physics to the eternal question of the existence of God, and an array of subjects are covered, from philosophy, the arts and religion, to mathematics and science.

Winner of the Premio Iberoamericano Book Award in 1997 What form does the crisis of modernity take in Latin America when societies are politically demobilized and there is no revolutionary agenda in sight? How does postmodern criticism reflect on enlightenment and utopia in a region marked by incomplete modernization, new waves of privatization, great masses of excluded peoples, and profound sociocultural heterogeneity? In _No Apocalypse, No Integration _Martín Hopenhayn examines the social and philosophical implications of the triumph of neoliberalism and (...) the collapse of leftist and state-sponsored social planning in Latin America. With the failure of utopian movements that promised social change, the rupture of the link between the production of knowledge and practical intervention, and the defeat of modernization and development policy established after World War II, Latin American intellectuals and militants have been left at an impasse without a vital program of action. Hopenhayn analyzes these crises from a theoretical perspective and calls upon Latin American intellectuals to reevaluate their objects of study, their political reality, and their society’s cultural production, as well as to seek within their own history the elements for a new collective discourse. Challenging the notion that strict adherence to a single paradigm of action can rescue intellectual and cultural movements, Hopenhayn advocates a course of epistemological pluralism, arguing that such an approach values respect for difference and for cultural and theoretical diversity and heterodoxy. This essay collection will appeal to readers of sociology, public policy, philosophy, cultural theory, and Latin American history and culture, as well as to those with an interest in Latin America’s current transition. (shrink)

This paper takes issue with a recent proposal due to Shogenji (Synthese 184:29–48, 2012). In his paper, Shogenji introduces J, a normatively motivated formal measure of justification (and of confirmation), and then proceeds to recruit it descriptively in an explanation of the conjunction fallacy. We argue that this explanation is undermined by the fact that it cannot be extended in any natural way to the inverse conjunction fallacy, a more recently discovered, closely related fallacy. We point out that since the (...) inverse conjunction fallacy occurs in the absence of any form of explicit evidence, formal measures of confirmation such as J, are hard pressed to apply to it at all. We then proceed to argue that this problem with Shogenji’s measure is actually quite difficult to come to terms with; even if the situations where people commit the inverse conjunction fallacy are understood in such a way that the measure is applicable, it doesn’t seem possible to reasonably interpret these situations in such a way that the measure can explain the found response pattern. (shrink)