The advent of ChatGPT by OpenAI has prompted extensive discourse on its potential implications for science and higher education. While the impact on education has been a primary focus, there is limited empirical research on the effects of large language models (LLMs) and LLM-based chatbots on science and scientific practice. To investigate this further, we conducted a Delphi study involving 72 researchers specializing in AI and digitization. The study focused on applications and limitations of LLMs, their effects on the science (...) system, ethical and legal considerations, and the required competencies for their effective use. Our findings highlight the transformative potential of LLMs in science, particularly in administrative, creative, and analytical tasks. However, risks related to bias, misinformation, and quality assurance need to be addressed through proactive regulation and science education. This research contributes to informed discussions on the impact of generative AI in science and helps identify areas for future action. (shrink)

Philosophy of Experimental Biology explores some central philosophical issues concerning scientific research in experimental biology, including genetics, biochemistry, molecular biology, developmental biology, neurobiology, and microbiology. It seeks to make sense of the explanatory strategies, concepts, ways of reasoning, approaches to discovery and problem solving, tools, models and experimental systems deployed by scientific life science researchers and also integrates developments in historical scholarship, in particular the New Experimentalism. It concludes that historical explanations of scientific change that are based on local laboratory (...) practice need to be supplemented with an account of the epistemic norms and standards that are operative in science. This book should be of interest to philosophers and historians of science as well as to scientists. (shrink)

Despite the importance of commitment in moral and political philosophy, there has hitherto been little extended analysis of it. Marcel Lieberman examines the conditions under which commitment is possible, and offers at the same time an indirect argument for moral realism. He argues that realist evaluative beliefs are functionally required for commitment - especially regarding its role in self-understanding - and since it is only within a realist framework that such beliefs make sense, realism about values is a condition (...) for the possibility of commitment itself. His ambitious study addresses questions that are of great interest to analytic philosophers but also makes many connections with continental philosophy and with folk psychology, sociology and cognitive science, and will be seen as a distinctive intervention in the debate about moral realism. (shrink)

I present a reconstruction of F.H.C. Crick's two 1957 hypotheses "Sequence Hypothesis" and "Central Dogma" in terms of a contemporary philosophical theory of causation. Analyzing in particular the experimental evidence that Crick cited, I argue that these hypotheses can be understood as claims about the actual difference-making cause in protein synthesis. As these hypotheses are only true if restricted to certain nucleic acids in certain organisms, I then examine the concept of causal specificity and its potential to counter claims about (...) causal parity of DNA and other cellular components. I first show that causal specificity is a special kind of invariance under interventions, namely invariance of generalizations that range over finite sets of discrete variables. Then, I show that this notion allows the articulation of a middle ground in the debate over causal parity. (shrink)

Causal selection is the task of picking out, from a field of known causally relevant factors, some factors as elements of an explanation. The Causal Parity Thesis in the philosophy of biology challenges the usual ways of making such selections among different causes operating in a developing organism. The main target of this thesis is usually gene centrism, the doctrine that genes play some special role in ontogeny, which is often described in terms of information-bearing or programming. This paper is (...) concerned with the attempt of confronting the challenge coming from the Causal Parity Thesis by offering principles of causal selection that are spelled out in terms of an explicit philosophical account of causation, namely an interventionist account. I show that two such accounts that have been developed, although they contain important insights about causation in biology, nonetheless fail to provide an adequate reply to the Causal Parity challenge: Ken Waters's account of actual-difference making and Jim Woodward's account of causal specificity. A combination of the two also doesn't do the trick, nor does Laura Franklin-Hall's account of explanation (in this volume). We need additional conceptual resources. I argue that the resources we need consist in a special class of counterfactual conditionals, namely counterfactuals the antecedents of which describe biologically normal interventions. (shrink)

The conduct of most of social science occurs outside the laboratory. Such studies in field science explore phenomena that cannot for practical, technical, or ethical reasons be explored under controlled conditions. These phenomena cannot be fully isolated from their environment or investigated by manipulation or intervention. Yet measurement, including rigorous or clinical measurement, does provide analysts with a sound basis for discerning what occurs under field conditions, and why. In Science Outside the Laboratory, Marcel Boumans explores the state of (...) measurement theory, its reliability, and the role expert judgment plays in field investigations from the perspective of the philosophy of science. Its discussion of the problems of passive observation, the calculus of observation, the two-model problem, and model-based consensus uses illustrations drawn primarily from economics. Rich in research and discussion, the volume clarifies the extent to which measurement provides valid information about objects and events in field sciences, but also has implications for measurement in the laboratory. Scholars in the fields of philosophy of science, social science, and economics will find Science Outside the Laboratory a compelling and informative read. (shrink)

v. 1. Reflection & mystery -- v. 2. Faith & reality.

Recent discussion of the statistical character of evolutionary theory has centered around two positions: (1) Determinism combined with the claim that the statistical character is eliminable, a subjective interpretation of probability, and instrumentalism; (2) Indeterminism combined with the claim that the statistical character is ineliminable, a propensity interpretation of probability, and realism. I point out some internal problems in these positions and show that the relationship between determinism, eliminability, realism, and the interpretation of probability is more complex than previously assumed (...) in this debate. Furthermore, I take some initial steps towards a more adequate account of the statistical character of evolutionary theory. (shrink)

Ideomotor theory of human action control proposes that activation of a motor representation can occur either through internally-intended or externally-perceived actions. Critically, sometimes these alternatives of eliciting a motor response may be conflicting, for example, when intending one action and perceiving another, necessitating the recruitment of enhanced action-control to avoid motor mimicry. Based on previous neuroimaging evidence, suggesting that reduced mimicry is associated with self-related processing, we aimed to experimentally enhance these action-control mechanisms during motor contagion by inducing self-focus. In (...) two within-subjects experiments, participants had to enforce their action intention against an external motor contagion tendency under heightened and normal self-focus. During high self-focus participants showed reduced motor mimicry, induced either by mirror self-observation or self-referential judgments. This indicates that a self-focus provoking situation can enhance online action-control mechanisms, needed to resist unintentional motor contagion tendencies and thereby enables a modulation of automatic mirroring responses. (shrink)

Many ethical concerns surrounding human genetics studies remain unresolved. We report here the situation in Cameroon.Objectives: To describe the profile of human genetic studies that used Cameroonian DNA samples, with specific focus on i) the research centres that were involved, ii) authorship, iii) population studied, iv) research topics and v) ethics disclosure, with the aim of raising ethical issues that emerged from these studies.Method: Bibliometric Studies; we conducted a PubMed-based systematic review of all the studies on human genetics that used (...) Cameroonian DNA samples from 1989 to 2009.Results and Discussion: Fifty articles were identified, involving predominantly research centres from Europe (64%) and America (32%). Only 7 (14%) Cameroonian institutions and 14 (28%) Cameroonian authors were associated with these publications.At least 52% of publications were devoted to population genetics (variation/migration patterns) amongst 30 Cameroonian ethnic groups. Very few studies concerned public health related genetic issues and only 5 (10%) references were found for hemoglobinopathies like sickle cell anaemia. Almost all DNA samples are ‘banked’ outside of the African continent.Capacity building, rights to the genetic information and benefits to the individuals, communities and populations who contribute to these studies are addressed.Conclusions: 1) Our data suggests the need for a wider debate towards building capacity and addressing ethical issues related to human genomic research in sub-Saharan Africa and specifically in Cameroon; 2) National ethical guidelines and regulations concerning the collection, use and storage of human DNA are urgently needed in Cameroon. (shrink)

I want to exhibit the deeper metaphysical reasons why some common ways of describing the causal role of genes in development and evolution are problematic. Specifically, I show why using the concept of information in an intentional sense in genetics is inappropriate, even given a naturalistic account of intentionality. Furthermore, I argue that descriptions that use notions such as programming, directing or orchestrating are problematic not for empirical reasons, but because they are not strictly causal. They are intentional. By contrast, (...) other notions that are part of the received view in genetics and evolutionary theory are defensible if understood correctly, in particular the idea that genes are the main replicators in evolution. The paper concludes that dropping all intentional or intentionally laden concepts does not force us to accept the so-called causal parity thesis, at least not in its stronger form. (shrink)

This paper examines causal theories of reference with respect to how plausible an account they give of non-physical natural kind terms such as ‘gene’ as well as of the truth of the associated theoretical claims. I first show that reference fixism for ‘gene’ fails. By this, I mean the claim that the reference of ‘gene’ was stable over longer historical periods, for example, since the classical period of transmission genetics. Second, I show that the theory of partial reference does not (...) do justice to some widely held realist intuitions about classical genetics. This result is at loggerheads with the explicit goals usually associated with partial theories of reference, which is to defend a realist semantics for scientific terms. Thirdly, I show that, contrary to received wisdom and perhaps contrary to physics and chemistry, neither reference fixism nor partial reference are necessary in order to hold on to scientific realism about biology. I pinpoint the reasons for this in the nature of biological kinds, which do not even remotely resemble natural kinds (i.e., Lockean real essences) as traditionally conceived. (shrink)

We observe a number of connections between recent developments in the study of constraint satisfaction problems, irredundant axiomatisation and the study of topological quasivarieties. Several restricted forms of a conjecture of Clark, Davey, Jackson and Pitkethly are solved: for example we show that if, for a finite relational structure M, the class of M-colourable structures has no finite axiomatisation in first order logic, then there is no set (even infinite) of first order sentences characterising the continuously M-colourable structures amongst compact (...) totally disconnected relational structures. We also refute a rather old conjecture of Gorbunov by presenting a finite structure with an infinite irredundant quasi-identity basis. (shrink)

The purpose of this article is to explore some of the non-obvious characteristics of the social science research-social policy (SSRSP) paradigm. We examine some of the underlying assumptions of the readily accepted claim that social science research can lead to the creation of rational social policy. We begin by using the framework of meta-analysis as one of the most powerful means of informing policy by way of empirical research findings. This approach is critiqued and found wanting in several ways. Several (...) conceptual and definitional issues connected to the term “policy” are explored as well. A central argument is that even the best social science research is no guarantee of enlightened policymaking because the very (inductive) basis of empirical research militates against the possibility of going from research findings to policy. This claim is explored within the context of a central paradox. This paradox is explored in some depth. Finally, within the SSRSP claim, we analyze related issues such as the possibility of utilizing Mixed Methods and the politics of policymaking. We conclude that the SSRSP framework is, at best, a subjective one which ironically is needed, but one which is constrained by the very methods that is uses to formulate policy. (shrink)

Do people share their feelings of guilt with others and, if so, what are the reasons for doing this or not doing this? Even though the social sharing of negative emotional experiences, such as regret, has been extensively studied, not much is known about whether people share feelings of guilt and why. We report three studies exploring these questions. In Study 1, we re-analysed data about sharing guilt experiences posted on a social website called “Yahoo Answers”, and found that people (...) share intrapersonal as well as interpersonal guilt experiences with others online. Study 2 found that the main motivations of sharing guilt (compared with the sharing of regret) were “venting”, “clarification and meaning”, and “gaining advice”. Study 3 found that people were more likely to share experiences of interpersonal guilt and more likely to keep experiences of intrapersonal guilt to themselves. Together, these studies contribute to a further understanding of the social sharing of the emotion guilt. (shrink)

El modelo viquiano propuesto en este trabajo tiene hoy día implicaciones concretas para la lingüística y las ciencias cognitivas. A nuestro parecer, hoy las investigaciones en estos campos no hacen otra cosa que verificar la existencia de un vínculo gnoseológico entre sentido, concepto y metáfora que Vico exponía en la Scienza nuova. Vico demostró, ante todo, que la lógica poética constituye la facultad preliminar que permite el comportamiento simbólico humano. Dicha noción falta del todo en las actuales investigaciones sobre la (...) metáfora; y falta claramente la noción de Homo Poeticus en todas las visiones hasta ahora expuestas en lingüística. La concepción viquiana de la lógica poética permitirá a estas ciencias trazar el recorrido científico que deberán seguir en el futuro.Recent researches in linguistics and cognitive sciences may be brought as to show that there exist a empistemological bound between sense, concept and metaphor which Vico already acknowledged in his Scienza nuova. While Vico clearly showed that poetical logic helps to developing the human symbolic behavior; the concept of Homo poeticus is lacking in recent scholar contributions on issues related with metaphors and linguistics. It is assumed that the Vichian conception on poetical logic may improve a better understanding of the problems with which those sciences have hitherto been concerned. (shrink)

In this article we investigate the way modern democracies can deal with extremists in public discussion. The first part of the article conceptualizes political discussion insofar as it makes a contribution to the democratic process. We focus upon the democratic process as a way of dealing with conflicts between citizens that stem from differences in moral outlook. We reflect upon this process mainly in relation to its capacity to overcome possible political deadlocks, in the perspective of collective decision making. In (...) the second part we concentrate on the question of how public discussion in a modern democracy should look. Here, then, we take a similar perspective as Gutmann and Thompson (1996) in saying that we should try and define some central ‘rules of the game’ for public discussion. We make a distinction between entrance rules that are proscriptive and performative rules that are suggestive. (shrink)

To define abstract art, which occupies such an important place in contemporary aesthetics, merely as a plastic mode of expression that makes no attempt to seek its own forms among those already existing in reality is to give a very inadequate notion of it. The term “non-figurative art,” which is sometimes used to describe it, arbitrarily restricts its range by stressing as peculiar to it this elementary fact alone and by characterizing abstract art solely as a controversial or even as (...) a revolutionary art, as opposed to traditional aesthetics, which is itself figurative. Abstract art at times has also been called “concrete” or “non-objective” art. All these definitions have as little validity in themselves as those that are made use of in the history of art and are acceptable only at their “face value,” to use the monetary term, because they have no absolute value but merely a conventional one based on the principle of exchange (Baroque, Gothic, Rococo, Cubist). However, they are not to be ignored, since they do express the state of uncertainty, uneasiness, and indecision that afflicts most amateurs and even historians of art in regard to abstract art. At the same time, these definitions also indicate an awareness that we are dealing with a very important and complex phenomenon, enriched by extensive projections into the domain of social psychology, sociology, and probably even metaphysics. (shrink)

Assessment of error and uncertainty is a vital component of both natural and social science. This edited volume presents case studies of research practices across a wide spectrum of scientific fields. It compares methodologies and presents the ingredients needed for an overarching framework applicable to all.

[1] Avec des "si" -- 2. Oisivetés -- 3. Noms -- 4. Diversités -- 5. Corsica.

We characterize the 3-stratifiable theorems of NF as a 3-stratifiable extension of NF 3 ; and show that NF is equiconsistent with TT plus raising type axioms for sentences asserting the existence of some predicate over an atomic Boolean algebra.