This paper proposes a conceptual framework to study and evaluate the impact of ‘Algorithmic Management’ (AM) on worker dignity. While the literature on AM addresses many concerns that relate to the dignity of workers, a shared understanding of what worker dignity means, and a framework to study it, in the context of software algorithms at work is lacking. We advance a conceptual framework based on a Capability Approach (CA) as a route to understanding worker dignity under AM. This paper contributes (...) to the existing AM literature which currently is mainly focused on exploitation and violations of dignity and its protection. By using a CA, we expand this focus and can evaluate the possibility that AM might also enable and promote dignity. We conclude that our CA-based conceptual framework provides a valuable means to study AM and then discuss avenues for future research into the complex relationship between worker dignity and AM systems. (shrink)

Clinical mental health researchers may understandably struggle with how to incorporate biological assessments in clinical research. The options are numerous and are described in a vast and complex body of literature. Here we provide guidelines to assist mental health researchers seeking to include biological measures in their studies. Apart from a focus on behavioral outcomes as measured via interviews or questionnaires, we advocate for a focus on biological pathways in clinical trials and epidemiological studies that may help clarify pathophysiology and (...) mechanisms of action, delineate biological subgroups of participants, mediate treatment effects, and inform personalized treatment strategies. With this paper we aim to bridge the gap between clinical and biological mental health research by (1) discussing the clinical relevance, measurement reliability, and feasibility of relevant peripheral biomarkers; (2) addressing five types of biological tissues, namely blood, saliva, urine, stool and hair; and (3) providing information on how to control sources of measurement variability. (shrink)

In recent years, business ethics and economic scholars have been paying greater attention to the development of commons organizing. The latter refers to the processes by which communities of people work in common in the pursuit of the common good. In turn, this promotes commons organizational designs based on collective forms of common goods production, distribution, management and ownership. In this paper, we build on two main literature streams: the ethical approach based on the theory of the common good of (...) the firm in virtue ethics and the economic approach based on the theory of institutions for collective action developed by Ostrom’s research on common-pool resources to avert the tragedy of the commons. The latter expands to include the novel concepts of new commons, “commoning” and polycentric governance. Drawing on the analysis of what is new in these forms of organizing, we propose a comprehensive model, highlighting the integration of two sets of organizing principles—common good and collective action – and five problem-solving processes to explain the main dimensions of commons organizing. We contribute to business ethics literature by exploring the convergence between the ethical and economic approaches in the development of a commons organizing view. (shrink)

How does violence shape citizens’ preferences for conflict termination? The existing literature has argued that violence either begets sympathy for more violence or drives support for making peace. Focusing on the 2016 Colombian Peace Agreement, this article finds that victimhood dissociation strongly shapes these preferences. With victimhood dissociation, a discrepancy exists between objective and subjective victimization, and the effect of violence on peace attitudes depends on citizens’ subjective interpretations of their personal experiences of violence. Citizens who do not experience violence (...) often see themselves as victims of the conflict and vice versa. Victimhood dissociation is linked to cultural stereotypes of victimhood as portrayed in elite narratives concerning the conflict. In Colombia, political leaders framed victimhood around rurality, business entrepreneurship, kidnapping, extortion, and disappearance. In 2016, this widespread narrative was instrumental for politicians opposing the peace agreement. Citizens who disassociated their personal experiences of violence from their self-understanding as victims were instrumental to the failure of the peace plebiscite. (shrink)

Recent revisions in child support and paternity establishment legislation enacted under the 1996 welfare reform act, the Personal Responsibility and Work Opportunity Reconciliation Act, significantly alter the American welfare state's relationship to men's fathering. Through a critical review of prior research and social service literature, the authors argue that PRWORA actively constructs fatherhood not only through state policies that maintain males as “breadwinners” but also through state-sponsored social service programs that seek to influence men's identities as fathers. PRWORA's policies and (...) their accompanying discourses simultaneously reproduce and undermine gender hierarchy yet tacitly maintain structural race and class inequalities. (shrink)

Environmental ethicists have frequently criticized ancient Greek philosophy as anti-environmental for a view of philosophy that is counterproductive to environmental ethics and a view of the world that puts nature at the disposal of people. This provocative collection of original essays reexamines the views of nature and ecology found in the thought of Plato, Aristotle, the Stoics, and Plotinus. Recognizing that these thinkers were not confronted with the environmental degradation that threatens contemporary philosophers, the contributors to this book find that (...) the Greeks nevertheless provide an excellent foundation for a sound theory of environmentalism. (shrink)

Background: The United Kingdom has the highest incarceration rate in Western Europe. It is known that women in prison are a vulnerable female population who are at risk of mental ill-health due to disadvantaged and chaotic life experiences. Accurate numbers of pregnant women held in UK prisons are not recorded, yet it is estimated that 6%–7% of the female prison population are at varying stages of pregnancy and around 100 babies are born to incarcerated women each year. There are limited (...) published papers that document the departure of the researcher following closure of fieldwork with women in prison. This article identifies the dilemmas and challenges associated with the closure of prison fieldwork through the interwoven reflections of the researcher. Departure scenarios are presented which illuminate moments of closure talk with five women, supported by participant reflections regarding abandonment and loss, making pledges for the future, self-affirmation, incidental add-ons at the end of an interview and red flags, alerting the researcher to potential participant harm through ill health or self-injury. Objectives: The primary intention of the study was to observe the pregnant woman’s experience with the English prison system through interviews with pregnant women and field observations of the environment. Research design: Ethnographic design enabled the researcher, a practising midwife, to engage with the prisoners’ pregnancy experiences in three English prisons, which took place over 10 months during 2015–2016. Data collection involved semi-structured, audio-recorded interviews with 28 female prisoners in England who were pregnant or had recently given birth while imprisoned, 10 members of staff and a period of non-participant observation. Follow-up interviews with 5 women were undertaken as their pregnancies progressed. Computerised qualitative data analysis software was used to generate and analyse pregnancy-related themes. Ethical considerations: Favourable ethical opinion was granted by National Offender Management Services through the Health Research Authority Integrated Research Application System and permission to proceed was granted by the University of Hertfordshire, UK. Findings: Thematic analysis enabled the identification of themes associated with the experience of prison pregnancy illuminating how prison life continues with little consideration for their unique physical needs, coping tactics adopted and the way women negotiate entitlements. On researcher departure from the field, the complex feelings of loss and sadness were experienced by both participants and researcher. Discussion: To leave the participant with a sense of abandonment following closure of fieldwork, due to the very nature of the closed environment, risks re-enactment of previous emotional pain of separation. Although not an ethical requirement, the researcher sought out psychotherapeutic supervision during the fieldwork phase with ‘Janet’, a forensic psychotherapist, which helped to highlight the need for careful closure of research/participant relationships with a vulnerable population. This article brings to the consciousness of prison researchers the need to minimise potential harm by carefully negotiating how to exit the field. Reflections of the researcher are interlinked with utterances from some participants to illustrate the types of departure behaviours. Conclusion: Closure of fieldwork and subsequent researcher departure involving pregnant women in prison requires careful handling to uphold the ethical research principle ‘do no harm’. (shrink)

We examined disgust and fear responses to spiders in spider-distressed and nondistressed individuals. Undergraduate participants (N = 134) completed questionnaires concerning responses to spiders and other potentially aversive stimuli, as well as measures of disgust sensitivity, anxious arousal, worry, and anhedonic depression. In addition, we obtained self-report and facial expressions of disgust and fear while participants were exposed to a live tarantula. Both spider distressed and nondistressed individuals reported disgust and exhibited disgust facial expressions in response to a tarantula. Disgust (...) in response to spiders was not found to be part of a general disgust response to all negative stimuli, nor was it due to a general negative emotional response to spiders. Emotional responses to spiders were differentially associated with scores on personality and psychological functioning measures. The results of this study provide evidence that spiders have a specific disgust-evoking status in both distressed and nondistressed populations. (shrink)

The concept offreedom in Heidegger’s sense of truth or unconcealedness of beings may be applied to future generations without thereby reducing the status of other elements within the environment to mere means, since Da-sein’s approach as one who is a caring and concernful, anxious and aware of its own death in an authentic manner, does not place man in any sense “above” other things. This care (Sorge), concern, favor can be captured in Heidegger’s remark that man is not the lord (...) of beings, but rather is “the Shepherd of Being.” Accordingly. we may be able to learn to moderate our ordering andcommanding attitude and learn to “listen” and free beings. letting them be what they truly are. If so, we might then require no special justification in order to extend toward earth, sky, and future persons the same understanding and freeing concern we normally give to, and wish for ourselves. (shrink)

Laura Berchielli - Color, Space and Figure in Locke: An Interpretation of the Molyneux Problem - Journal of the History of Philosophy 40:1 Journal of the History of Philosophy 40.1 47-65 Color, Space, and Figure in Locke: An Interpretation of the Molyneux Problem Laura Berchielli THIS IS HOW LOCKE, in the second edition of his Essay Concerning Human Understanding , introduces a question that had been suggested to him in a letter from William Molyneux: . . . I (...) shall here insert a Problem of that very Ingenious and Studious promoter of Knowledge, the Learned and Worthy Mr. Molineux, which he was pleased to send me in a Letter some Months since; and it is this: Suppose a Man born blind, and now adult, and taught by his touch to distinguish between a Cube, and a Sphere of the same metal, and nighly of the same bigness, so as to tell, when he felt one and t'other, which is the Cube, which the Sphere. Suppose then the Cube and Sphere placed on a Table, and the Blind Man to be made to see. Quaere, Whether by his Sight, before he touch'd them, he could now distinguish, and tell, which is the Globe, which the Cube. In the standard interpretation of the Molyneux problem as presented in Locke, the question is always linked to the general issue of differences in the ideas of figure received by the various senses. This interpretation -- put forward by Berkeley --says that for Locke, the ideas of figure produced by sight are specifically different from.. (shrink)

Many countries, including Australia, have established a national scheme that supports the recognition of a single ethical review for multi-centre research conducted in publicly funded health services. However, local site-specific governance review processes remain decentralised and highly variable. This short report describes the ethics and governance processes required for a negligible risk national survey of physiotherapy-led airway clearance services in Australia. We detail inconsistencies in research governance document preparation and submission (platforms, processes, forms and signatories) and report the time cost (...) and likely impact of these inconsistencies on health services research outcomes. Processes and strategies that facilitated success in this project are identified and summarised as helpful hints to other researchers looking to embark on negligible risk research in public health facilities. (shrink)

A presente pesquisa visou a explorar brevemente as relações entre as obras do jovem Michelangelo e a influência teórica do platonismo e neoplatonismo que se disseminaram em Florença durante a época de Lorenzo, o Magnífico. Para empreender o projeto com clareza, dividiu-se a abordagem em quatro momentos, sendo eles: i) uma introdução geral; ii) o cenário Florentino e a filosofia platônica; iii) a filosofia platônica, seus principais pontos e a recuperação de seus conceitos pelos humanistas renascentistas; e iv) a influência (...) platônica sobre o jovem Michelangelo. Assim, buscou-se, sem pretensões de esgotar o tema, demonstrar em que medida as formas artísticas de Michelangelo e suas concepções filosóficas estão profundamente interligadas.Palavras-chave: Platão. Neoplatonismo. Arte. Michelangelo. Humanismo. (shrink)

Nas últimas duas décadas a estética do cotidiano tornou-se um importante tema de debate entre filósofos de tradição anglófona. Essa teoria contempla a possibilidade de que o cotidiano seja fonte de experiências estéticas, além de realizar uma crítica da tradição. Ambos os elementos também estão presentes e são centrais para a estética pragmatista desenvolvida por John Dewey na primeira metade do século XX. Neste breve ensaio, realiza-se uma aproximação dos dois projetos teóricos por meio de um eixo de questão em (...) comum, a saber, o dilema de como é possível relacionar a estética e a vida cotidiana. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:IntroductionStuart J. Youngner (bio), Laura A. Siminoff (bio), and Renie Schapiro (bio)This issue of the Kennedy Institute of Ethics Journal (KIEJ) centers on a piece of empirical research. The motivation behind the study of Laura Siminoff, Christopher Burant, and Stuart Youngner (2004) was to find out more about what the general public understands and believes about when a person is dead. More specifically, the study tried to (...) determine how members of the public define death, especially their acceptance and interpretation of the medical concept of "brain death," and their attitudes toward the so-called "dead donor rule," an informal but powerful social and legal norm insisting that the taking of organs for transplantation not cause the death of the source of those organs.As the demand for organs increases and the waiting list grows, the United States has explored multiple ways to expand the pool of potential donors. One approach has been to gerrymander (coherently or not) the line between life and death to shift patients who are extremely compromised but traditionally considered to be in the living category into the dead category. In this way, the dead donor rule remains technically intact. This reasoning is explicit in the report of the Harvard Medical School Ad Hoc Committee (1968) that "introduced" "brain death" to the American culture. Since then, other efforts to redraw the line have been proposed and rejected.One alternative to gerrymandering is to consider under what conditions, if any, it is morally acceptable to violate the dead donor rule. Some would argue that this alternative is the more "honest" approach. Rather than sidestepping moral problems by calling people dead, it brings the moral problems to the surface where the necessity of sticking to the rule can be considered on its own merits. However, when the Journal of the American Medical Association printed a position paper that proposed making anencepahlic newborns an exception to the dead donor rule, along with arguments about why this was acceptable, the outcry was so great that the proposal was retracted (AMA 1995).Clearly, our society has identified organ transplantation as a priority, although two papers in this volume (those by Courtney Campbell and by Megan Crowley-Matoka and Robert Arnold) take issue with that prioritization. The fact that the donor pool has remained relatively stable (and inadequate) despite massive efforts [End Page 211] to increase it speaks, at least in part, to the cultural and legal resistance to "new" ways to procure more organs. Voluntarism seems to have peaked. Financial incentives clash with the heavily endorsed notion of the "gift of life" and seem to many to violate the dignity of the human body. Presumed consent or eminent domain, in which the community has a greater claim to a person's organs than that person or his/her family, go against the grain of American individual freedom and the ethos of patient autonomy.Abandoning the dead donor rule generally is regarded as an even tougher sell to the American public and its legislators. The study by Siminoff and colleagues attempts, among other things, to gauge just how tough this sell would be. What the data actually demonstrate is a matter of interpretation, and this issue of the KIEJ is devoted to some of those interpretations. The authors, with the exception of Daniel Hausman, came together for a meeting in Cleveland, Ohio, during which the study's methods and data were presented with time for questions, clarifications, and general discussion. The authors then worked with the editors to generate the papers printed in this volume.The issue begins with a presentation of the study conducted by Siminoff and colleagues. The same paper also appears in the journal Social Science and Medicine, where it includes the conclusions of the authors (Siminoff, Burant, and Youngner 2004). In the current volume, we present only the methodology of and data from the study, allowing a number of distinguished commentators to offer their own conclusions and reflections.The first response comes from Tracy Schmidt, Executive Director of Intermountain Donor Services, one of our nation's organ procurement organizations (OPOs). For years, organ procurement professionals have reported anecdotal stories about families who wished to donate organs of... (shrink)

En el presente trabajo nos proponemos reflexionar acerca de las posibilidades, límites y desafíos que se presentan en la práctica docente cuando jóvenes de sectores subalternos emprenden la tarea de escribir sus propias historias. Estas reflexiones surgen a partir de una experiencia pedagógica desarrollada en el marco del Programa Pueblos Originarios y Escuelas Rurales de la UNCuyo. Consideramos que la fragmentación y la discontinuidad es un rasgo de la memoria colectiva de los sectores subalternos, sin embargo, en ocasiones encuentra espacios (...) para expresarse y tensionar la historia oficial. En esa dirección, en esta ocasión, decidimos convertir nuestros espacios curriculares en ámbitos de reflexión personal y colectiva donde los y las subalternos (parafraseando a la filósofa india Gayatri Spivak) “pudieron hablar”, para luego plasmar sus historias en fanzines. (shrink)

Mathematics and aesthetics are closely intertwined. Not only mathematical concepts, relationships and theorems can be aesthetically pleasing, but we also often find harmony between their results and the patterns of the world around us, and we like that. Yet, apart from rare exceptions, the beauty of mathematics, particularly in education, is mostly unrecognized: this science rarely meets the favour of students. Vedic mathematics is an approach which encapsulates the enjoyment and power of this knowledge, not only in the sphere of (...) thought process, but also in its practical utility. It highlights and develops the aesthetic dimension of learning in a very immediate sense. The aim of this article is to introduce the method – what it is and how it works – to give comparative examples of techniques and their efficacy, and to emphasize the aesthetic value it conveys. (shrink)

This essay compares Sikh and Christian thought about and practices of hospitality in light of the global refugee crisis. It aims to show how both practices of hospitality, and religious ethical thought about hospitality, can be enhanced by dialogue between traditions. The refugee crisis arises out of a global failure of hospitality, and the type of hospitality refugees most fundamentally need is that which confers membership in a political community. Comparing Christian and Sikh ethics of hospitality provides guidance toward building (...) rooted religious communities that welcome outsiders, including by incorporating them into political communities. In particular, Christians who hold social power and privilege can better fulfill ethical mandates of hospitality by looking to the example of Sikhs and other marginalized groups. Sikhs have often built communities through acts of hospitality and welcomed outsiders without fear, even in contexts where their own belonging is questioned and their own security is under threat. (shrink)

Aristotle's Topics is a handbook for dialectic, which can be understood as a philosophical debate between a questioner and a respondent. In book 2, Aristotle mainly develops strategies for making deductions about 'accidents', which are properties that might or might not belong to a subject (for instance, Socrates has five fingers, but might have had six), and about properties that simply belong to a subject without further specification. In the present commentary, here translated into English for the first time, Alexander (...) develops a careful study of Aristotle's text. He preserves objections and replies from other philosophers whose work is now lost, such as the Stoics. He also offers an invaluable picture of the tradition of Aristotelian logic down to his time, including innovative attempts to unify Aristotle's guidance for dialectic with his general theory of deductive argument (the syllogism), found in the Analytics. The work will be of interest not only for its perspective on ancient logic, rhetoric, and debate, but also for its continuing influence on argument in the Middle Ages and later. (shrink)

Dentro de las posturas que consideran que los animales tienen estatus moral, hay dos tipos de posturas: las que consideran que los animales tienen el mismo estatus moral que los humanos, y las que consideran que los animales tienen menos estatus moral que los humanos. En este artículo argumento que ambos tipos de posturas son práctica y teóricamente equivalentes. En primer lugar, argumentaré que dichas posturas no hacen ninguna diferencia práctica, en tanto desde ellas pueden justificarse los mismos juicios morales. (...) En segundo lugar, argumentaré que, aunque superficialmente pareciera que los mismos juicios morales se justifican de distinta manera desde cada tipo de postura, haciendo un análisis más profundo puede verse que esto no es el caso. De este modo, tampoco hay una diferencia teórica sustancial entre los dos tipos de posturas. Por lo tanto, estos dos tipos de posturas no constituyen diferentes opciones en la defensa de los derechos de los animales. (shrink)

New agricultural technologies are often justified morally in terms of their expected benefits, e.g., feeding the world's hungry. Such justifications stand or fall, not only on whether such benefits are indeed forthcoming, but on whether or not they are outweighed by attendant dangers. The practical details of easch case are, therefore, all-important. In this paper agriculture and aquaculture are examined from the perspective of ecosystem integrity, and with further reference to the uncertain effects of anthropogenic changes in the earth's atmosphere. (...) The principle of integrity provides a strong justification for a cautious approach to new technologies, and particularly so in the case of transgenics. (shrink)

Present laws and regulations even in democratic countries are not sufficient to prevent the grave environmental threats we face. Further, even environmental ethics, when they remain anthropocentric cannot propose a better approach. I argue that, taking in considerations the precautionary principle, and adopting the perspective of post-normal science, the ethics of integrity suggest a better way to reduce ecological threats and promote the human good globally.

‘Contingent Valuation ’ is a method often used to make decisions about environmental issues. It is used to elicit citizens’ preferences at the location of a specific facility, new road and the like. I argue that even if we could elicit a truly informed and ‘free’ choice, the method would remain flawed, as 1) all ‘local’ activity also has far-reaching environmental consequences; 2) majority decisions may support chices that adversely affect minorities; 3) even with full information, consenting to harms like (...) significant alterations of our normal functioning or health, or genetic mutations, may not be morally acceptable. (shrink)

William James states “Immortality is one of the great spiritual needs of man,” yet the arguments presented in his LECTURE ON IMMORTALITY, while interesting and ingenious, are somewhat less than conclusive in proving that human beings can survive bodily death. Therefore I attempt to clarity the notion of “individual survivor” through an analysis and discussion of various approaches to the problem, before returning to a further examination of James’ thought in the “Final Impressions of a Psychical Researcher,” the THEORY OF (...) THE SOUL, the PRINCIPLES OF PSYCHOLOGY, the VARIETIES OF RELIGIOUS EXPERIENCE and a PLURALISTIC UNIVERSE. James’ often neglected Christian position provides the key to a better understanding of his thought on the topic, and allows me to conclude on a cautiously optimistic note on the possibility of a philosophical proof for human survival. (shrink)

The main objective of performance sport is to obtain achievements at the highest level through the adequate development of the athlete. The scientific literature demonstrates the fundamental role played by the inclusion of certain psychological variables in the training plan. This study examined the psychological profile of kayak polo players through the variables of burnout, optimism, and mood in the hours prior to the competition, relating these to each other and to some sociodemographic data. A sample of 86 canoeists, 60 (...) men and 26 women, with an age measurement of 24.4 ± 9.1 years belonging to the first male and female kayak polo division, completed the POMS-29, the LOT-R, and the IBD-R. Athletes' levels of optimism were found to be significantly correlated with mood. Optimism also influenced emotional exhaustion. In addition, seniority and internationality were decisive factors in the level of optimism and mood achieved. (shrink)

Psychology research on men studies, attractiveness, and partner preferences has evolved from the influence of sociobiological perspectives to the role of interactions in shaping election toward sexual–affective relationships and desire toward different kinds of masculinities. However, there is a scientific gap in how language and communicative acts among women influence the kind of partner they feel attracted to and in the reproduction of relationship double standards, like the myth of the “warrior’s rest” where female attractiveness to “bad boys” is encouraged (...) or supported. Some women imitate “the warrior” behavior of men by choosing dominant traditional masculinities (DTM) to have “fun” with and oppressed traditional masculinities (OTM) for “rest” after the “fun” with DTM—choosing an OTM for a stable relationship, but perhaps without passion, while also feeling attraction toward DTM, a response which perpetuates the chauvinist double standard that the feminist movement has condemned when men behave in this sexist way. Through conducting a qualitative study with communicative daily life stories, this article explores, on the one hand, how language and social interaction among women can lead to the reproduction of the DTM role by women and, on the other hand, also how new alternative masculinities (NAM) offer an alternative by explicitly rejecting, through the language of desire, to be the rest for the female warrior, the second fiddle to any woman. This has the potential to become a highly attractive alternative to DTM. Findings provide new knowledge through the analysis of communicative acts and masculinities evidencing the importance of language uses in the reproduction of the double standards in gender relations and to understand how and why these practices are maintained and which kind of language uses can contribute to preventing them. Implications for research and interventions on preventive socialization of gender violence are discussed. (shrink)

En La hermeneútica del sujeto, Foucault sostiene que, en la cultura de sí, existieron pedagogía y psicagogía como dos formas de educación, diferenciadas en virtud de la finalidad ethopoietica de cada una. No obstante, no resulta claro qué quiere decir esto, pues la distinción se realiza sin una aclaración del marco en el que tiene lugar. En este artículo nos proponemos destacar los aspectos constitutivos de la psicagogía, problematizando el modo en que aquí es entendida la ethopoiesis, a través de (...) la cual intentaremos explicitar su remisión a los conceptos de veridicción y cuidado de sí. (shrink)

In an effort to respond to the large surge in COVID-19 cases in Arizona that began between May and July 2020, the Arizona State University (ASU) Student Outbreak Response Team (SORT) formed a remote, volunteer-based case investigation team that worked in partnership with a local public health department through delegated public health authority.

The Hippo pathway, a cascade of protein kinases that inhibits the oncogenic transcriptional coactivators YAP and TAZ, was discovered in Drosophila as a major determinant of organ size in development. Known modes of regulation involve surface proteins that mediate cell‐cell contact or determine epithelial cell polarity which, in a tissue‐specific manner, use intracellular complexes containing FERM domain and actin‐binding proteins to modulate the kinase activities or directly sequester YAP. Unexpectedly, recent work demonstrates that GPCRs, especially those signaling through Galpha12/13 such (...) as the protease activated receptor PAR1, cause potent YAP dephosphorylation and activation. This response requires active RhoA GTPase and increased assembly of filamentous (F‐)actin. Morever, cell architectures that promote F‐actin assembly per se also activate YAP by kinase‐dependent and independent mechanisms. These findings unveil the ability of GPCRs to activate the YAP oncogene through a newly recognized signaling function of the actin cytoskeleton, likely to be especially important for normal and cancerous stem cells. (shrink)

Recent studies show that psychiatry residents express a relatively greater need for ethics curricula than their colleagues in other specialties. Such studies have been limited in their generalizability because they were conducted at one site. This study of 151 psychiatry residents at seven U.S. psychiatry programs aims to address that limitation. Residents were surveyed on issues pertaining to ethics and professionalism education. Participants were found to support such curricula during training and to value its relevance to the practice of psychiatry. (...) Gender differences and the influence of the “hidden curriculum” on such results merit further study. (shrink)

O presente estudo tem como objetivo conhecer os sentidos produzidos por ouvidores de vozes sobre suas experiências com as vozes. Trata-se de uma pesquisa qualitativa de caráter exploratório. Se deu através de entrevistas semi-estruturadas realizadas com dezesseis ouvidores de vozes usuários de um Centro de Atenção Psicossocial da cidade de Pelotas/RS. Evidenciou-se que o sentido que o ouvidor atribui às vozes é subjetivo, individual, e dependente de fatores externos, como os discursos a que esse ouvidor é exposto no seu meio (...) histórico e social ao longo do tempo. Fica nítida a importância de não se minimizar as características e os conteúdos das vozes, a fim de auxiliar os ouvidores a estabelecerem sentidos e possíveis relações com suas histórias de vida. (shrink)

Los avances de la biotecnología y las fascinantes perspectivas de la genómica nutricional en el escenario de la práctica clínica conducen a la consideración de distintos aspectos que impactan en el beneficio integral del ser humano. En ese sentido, la integración de la nutrición personalizada en la atención clínica requiere de un análisis bioético centrado en la unidad de la persona que, con base en su perfil nutrigenético único, contribuya al cuidado de la salud por medio del tratamiento nutricional individualizado. (...) El análisis bioético contempla los principios de totalidad terapéutica, libertad e integridad. Además, el uso de las pruebas nutrigenéticas destaca no solo la confidencialidad de datos, que se presupone, sino que lleva a considerar el derecho a la intimidad. (shrink)