Results for 'Julian Blow'

963 found
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  1.  18
    Eukaryotic DNA replication reconstituted outside the cell.J. Julian Blow - 1988 - Bioessays 8 (5):149-152.
    Our potential for dissecting the complex processes involved in eukaryotic DNA replication has been dramatically increased with the recent development of cell‐free systems that recreate many of these processes in vitro. Initial results from these systems have drawn together work on the cell cycle, the enzymology of replication, and the structure of the nucleus.
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  2.  20
    What the paper say: A protein complex present at origins of DNA replication in yeast cells.Julian Blow - 1992 - Bioessays 14 (8):561-563.
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  3.  58
    Partial-order Boolean games: informational independence in a logic-based model of strategic interaction.Julian Bradfield, Julian Gutierrez & Michael Wooldridge - 2016 - Synthese 193 (3):781-811.
    As they are conventionally formulated, Boolean games assume that players make their choices in ignorance of the choices being made by other players – they are games of simultaneous moves. For many settings, this is clearly unrealistic. In this paper, we show how Boolean games can be enriched by dependency graphs which explicitly represent the informational dependencies between variables in a game. More precisely, dependency graphs play two roles. First, when we say that variable x depends on variable y, then (...)
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  4. Good reasons to vaccinate: mandatory or payment for risk?Julian Savulescu - 2021 - Journal of Medical Ethics 47 (2):78-85.
    Mandatory vaccination, including for COVID-19, can be ethically justified if the threat to public health is grave, the confidence in safety and effectiveness is high, the expected utility of mandatory vaccination is greater than the alternatives, and the penalties or costs for non-compliance are proportionate. I describe an algorithm for justified mandatory vaccination. Penalties or costs could include withholding of benefits, imposition of fines, provision of community service or loss of freedoms. I argue that under conditions of risk or perceived (...)
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  5. The Moral Obligation to Create Children with the Best Chance of the Best Life.Julian Savulescu & Guy Kahane - 2008 - Bioethics 23 (5):274-290.
    According to what we call the Principle of Procreative Beneficence, couples who decide to have a child have a significant moral reason to select the child who, given his or her genetic endowment, can be expected to enjoy the most well-being. In the first part of this paper, we introduce PB, explain its content, grounds, and implications, and defend it against various objections. In the second part, we argue that PB is superior to competing principles of procreative selection such as (...)
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  6.  42
    Are viruses a source of new protein folds for organisms? – Virosphere structure space and evolution.Aare Abroi & Julian Gough - 2011 - Bioessays 33 (8):626-635.
    A crucially important part of the biosphere – the virosphere – is too often overlooked. Inclusion of the virosphere into the global picture of protein structure space reveals that 63 protein domain superfamilies in viruses do not have any structural and evolutionary relatives in modern cellular organisms. More than half of these have functions which are not virus‐specific and thus might be a source of new folds and functions for cellular life. The number of viruses on the planet exceeds that (...)
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  7. Evaluating Tradeoffs between Autonomy and Wellbeing in Supported Decision Making.Julian Savulescu, Heather Browning, Brian D. Earp & Walter Veit - 2021 - American Journal of Bioethics 21 (11):21-24.
    A core challenge for contemporary bioethics is how to address the tension between respecting an individual’s autonomy and promoting their wellbeing when these ideals seem to come into conflict (Not...
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  8. Philosophy of Economics: A Contemporary Introduction.Julian Reiss - 2013 - New York, NY: Routledge.
    Philosophy of Economics: A Contemporary Introduction is the first systematic textbook in the philosophy of economics. It introduces the epistemological, metaphysical and ethical problems that arise in economics, and presents detailed discussions of the solutions that have been offered. Throughout, philosophical issues are illustrated by and analysed in the context of concrete cases drawn from contemporary economics, the history of economic ideas, and actual economic events. This demonstrates the relevance of philosophy of economics both for the science of economics and (...)
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  9. Mach's principle and the structure of dynamical theories.Julian B. Barbour & Bruno Bertotti - 1982 - Proceedings of the Royal Society, London:295--306.
     
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  10.  87
    Why lockdown of the elderly is not ageist and why levelling down equality is wrong.Julian Savulescu & James Cameron - 2020 - Journal of Medical Ethics 46 (11):717-721.
    In order to prevent the rapid spread of COVID-19, governments have placed significant restrictions on liberty, including preventing all non-essential travel. These restrictions were justified on the basis the health system may be overwhelmed by COVID-19 cases and in order to prevent deaths. Governments are now considering how they may de-escalate these restrictions. This article argues that an appropriate approach may be to lift the general lockdown but implement selective isolation of the elderly. While this discriminates against the elderly, there (...)
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  11.  77
    Collective Reflective Equilibrium in Practice (CREP) and controversial novel technologies.Julian Savulescu, Christopher Gyngell & Guy Kahane - 2021 - Bioethics 35 (7):652-663.
    In this paper, we investigate how data about public preferences may be used to inform policy around the use of controversial novel technologies, using public preferences about autonomous vehicles (AVs) as a case study. We first summarize the recent ‘Moral Machine’ study, which generated preference data from millions of people regarding how they think AVs should respond to emergency situations. We argue that while such preferences cannot be used to directly inform policy, they should not be disregarded. We defend an (...)
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  12. Negative truths and truthmaker principles.Julian Dodd - 2007 - Synthese 156 (2):383-401.
    This paper argues that a consideration of the problem of providing truthmakers for negative truths undermines truthmaker theory. Truthmaker theorists are presented with an uncomfortable dilemma. Either they must take up the challenge of providing truthmakers for negative truths, or else they must explain why negative truths are exceptions to the principle that every truth must have a truthmaker. The first horn is unattractive since the prospects of providing truthmakers for negative truths do not look good neither absences, nor totality (...)
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  13. Assessing the Likely Harms to Kidney Vendors in Regulated Organ Markets.Julian Koplin - 2014 - American Journal of Bioethics 14 (10):7-18.
    Advocates of paid living kidney donation frequently argue that kidney sellers would benefit from paid donation under a properly regulated kidney market. The poor outcomes experienced by participants in existing markets are often entirely attributed to harmful black-market practices. This article reviews the medical and anthropological literature on the physical, psychological, social, and financial harms experienced by vendors under Iran's regulated system of donor compensation and black markets throughout the world and argues that this body of research not only documents (...)
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  14. Bioethics: why philosophy is essential for progress.Julian Savulescu - 2015 - Journal of Medical Ethics 41 (1):28-33.
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  15. Relational concepts of space and time.Julian B. Barbour - 1982 - British Journal for the Philosophy of Science 33 (3):251-274.
  16. Scale-invariant gravity: Particle dynamics.Julian B. Barbour - 2003 - Classical and Quantum Gravity 20:1543--70.
     
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  17. A Pragmatist Theory of Evidence.Julian Reiss - 2015 - Philosophy of Science 82 (3):341-362.
    Two approaches to evidential reasoning compete in the biomedical and social sciences: the experimental and the pragmatist. Whereas experimentalism has received considerable philosophical analysis and support since the times of Bacon and Mill, pragmatism about evidence has been neither articulated nor defended. The overall aim is to fill this gap and develop a theory that articulates the latter. The main ideas of the theory will be illustrated and supported by a case study on the smoking/lung cancer controversy in the 1950s.
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  18. Musical works as eternal types.Julian Dodd - 2000 - British Journal of Aesthetics 40 (4):424-440.
  19.  79
    Justice, Fairness, and Enhancement.Julian Savulescu - 2006 - Annals of New York Academy of Science 1093:321-338.
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  20.  32
    (1 other version)Two kinds of embryo research: four case examples.Julian Savulescu, Markus Labude, Capucine Barcellona, Zhongwei Huang, Michael Karl Leverentz, Vicki Xafis & Tamra Lysaght - 2022 - Journal of Medical Ethics 48 (9):590-596.
    There are ethical obligations to conduct research that contributes to generalisable knowledge and improves reproductive health, and this should include embryo research in jurisdictions where it is permitted. Often, the controversial nature of embryo research can alarm ethics committee members, which can unnecessarily delay important research that can potentially improve fertility for patients and society. Such delay is ethically unjustified. Moreover, countries such as the UK, Australia and Singapore have legislation which unnecessarily captures low-risk research, such as observational research, in (...)
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  21.  61
    An Embodied Predictive Processing Theory of Pain Experience.Julian Kiverstein, Michael D. Kirchhoff & Mick Thacker - 2022 - Review of Philosophy and Psychology 13 (4):973-998.
    This paper aims to provide a theoretical framework for explaining the subjective character of pain experience in terms of what we will call ‘embodied predictive processing’. The predictive processing (PP) theory is a family of views that take perception, action, emotion and cognition to all work together in the service of prediction error minimisation. In this paper we propose an embodied perspective on the PP theory we call the ‘embodied predictive processing (EPP) theory. The EPP theory proposes to explain pain (...)
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  22. Deflationism Trumps Pluralism!Julian Dodd - 2012 - In Nikolaj Jang Lee Linding Pedersen & Cory Wright, Truth and Pluralism: Current Debates. Oxford, England: Oxford University Press. pp. 298.
  23. What 4′33″ Is.Julian Dodd - 2018 - Australasian Journal of Philosophy 96 (4):629-641.
    ABSTRACTWhat is John Cage's 4′33″? This paper disambiguates this question into three sub-questions concerning, respectively, the work's ontological nature, the art form to which it belongs, and the genre it is in. We shall see that the work's performances consist of silence, that it is a work of performance art, and that it belongs to the genre of conceptual art. Seeing the work in these ways helps us to understand it better, and promises to assuage somewhat the puzzlement and irritation (...)
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  24. General relativity as a perfectly Machian theory.Julian B. Barbour - 1995 - In Julian B. Barbour & H. Pfister, Mach's Principle: From Newton's Bucket to Quantum Gravity. Birkhäuser. pp. 214--36.
     
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  25. Adventures in the metaontology of art: local descriptivism, artefacts and dreamcatchers.Julian Dodd - 2013 - Philosophical Studies 165 (3):1047-1068.
    Descriptivism in the ontology of art is the thesis that the correct ontological proposal for a kind of artwork cannot show the nascent ontological conception of such things embedded in our critical and appreciative practices to be substantially mistaken. Descriptivists believe that the kinds of revisionary art ontological proposals propounded by Nelson Goodman, Gregory Currie, Mark Sagoff, and me are methodologically misconceived. In this paper I examine the case that has been made for a local form of descriptivism in the (...)
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  26. Causation in the social sciences: Evidence, inference, and purpose.Julian Reiss - 2009 - Philosophy of the Social Sciences 39 (1):20-40.
    All univocal analyses of causation face counterexamples. An attractive response to this situation is to become a pluralist about causal relationships. "Causal pluralism" is itself, however, a pluralistic notion. In this article, I argue in favor of pluralism about concepts of cause in the social sciences. The article will show that evidence for, inference from, and the purpose of causal claims are very closely linked. Key Words: causation • pluralism • evidence • methodology.
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  27. Is truth supervenient on being?Julian Dodd - 2002 - Proceedings of the Aristotelian Society 102 (1):69–85.
    This paper asks whether we should accept a weakened version of the truthmaker principle: namely, the claim that truth supervenes on being, in which 'being' is understood as whether things are. I consider a number of positive answers to this question, including the following: that the truthmaker principle is a requirement of any plausible explanation of truth; that the principle must be accepted, if we are to do justice to the Wittgensteinian insight that the world is the totality of facts, (...)
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  28. McDowell and Identity Theories of Truth.Julian Dodd - 1995 - Analysis 55 (3):160 - 165.
    The main thesis of this paper is that John McDowell (in his Mind and World) tries to occupy a position that is not coherently statable; namely, that facts have objects and properties as constituents and are yet identical with true (Fregean) Thoughts. This position is contrasted with two other identity theories of truth: the robust theory, in which true propositions are identified with facts (which are understood to have objects and properties as constituents); and the modest theory, in which facts (...)
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  29. Pseudo-Transformational Leadership: Towards the Development and Test of a Model.Julian Barling, Amy Christie & Nick Turner - 2008 - Journal of Business Ethics 81 (4):851-861.
    We develop and test a model of pseudo-transformational leadership. Pseudo-transformational leadership is manifested by a particular combination of transformational leadership behaviors, and is differentiated from both transformational leadership and laissez-faire -leadership. Survey data from senior managers show differential outcomes of transformational, pseudo-transformational, and laissez-faire leadership. Possible extensions of the theoretical model and directions for future research are offered.
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  30.  56
    Why Do Experts Disagree?Julian Reiss - 2020 - Critical Review: A Journal of Politics and Society 32 (1):218-241.
    Jeffrey Friedman’s Power Without Knowledge argues forcefully that there are inherent limitations to the predictability of human action, due to a circumstance he calls “ideational heterogeneity.” However, our resources for predicting human action somewhat reliably in the light of ideational heterogeneity have not been exhausted yet, and there are no in-principle barriers to progress in tackling the problem. There are, however, other strong reasons to think that disagreement among epistocrats is bound to persist, such that it will be difficult to (...)
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  31. Identity and Harmony and Modality.Julian J. Schlöder - 2023 - Journal of Philosophical Logic 52 (5):1269-1294.
    Stephen Read presented harmonious inference rules for identity in classical predicate logic. I demonstrate here how this approach can be generalised to a setting where predicate logic has been extended with epistemic modals. In such a setting, identity has two uses. A rigid one, where the identity of two referents is preserved under epistemic possibility, and a non-rigid one where two identical referents may differ under epistemic modality. I give rules for both uses. Formally, I extend Quantified Epistemic Multilateral Logic (...)
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  32. Farewell to states of affairs.Julian Dodd - 1999 - Australasian Journal of Philosophy 77 (2):146 – 160.
  33. Performing Works of Music Authentically.Julian Dodd - 2012 - European Journal of Philosophy 23 (3):485-508.
    This paper argues that, within the Western ‘classical’ tradition of performing works of music, there exists a performance value of authenticity that is distinct from that of complying with the instructions encoded in the work's score. This kind of authenticity—interpretive authenticity—is a matter of a performance's displaying an understanding of the performed work. In the course of explaining the nature of this norm, two further claims are defended: that the respective values of interpretive authenticity and score compliance can come into (...)
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  34.  37
    Lessons from Frankenstein 200 years on: brain organoids, chimaeras and other ‘monsters’.Julian Koplin & John Massie - 2021 - Journal of Medical Ethics 47 (8):567-571.
    Mary Shelley’sFrankensteinhas captured the public imagination ever since it was first published over 200 years ago. While the narrative reflected 19th-century anxieties about the emerging scientific revolution, it also suggested some clear moral lessons that remain relevant today. In a sense,Frankensteinwas a work of bioethics written a century and a half before the discipline came to exist. This paper revisits the lessons ofFrankensteinregarding the creation and manipulation of life in the light of recent developments in stem cell and neurobiological research. (...)
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  35. Musical works: Ontology and meta-ontology.Julian Dodd - 2008 - Philosophy Compass 3 (6):1113-1134.
    The ontological nature of works of music has been a particularly lively area of philosophical debate during the past few years. This paper serves to introduce the reader to some of the most fertile and interesting issues. Starting by distinguishing three questions – the categorial question, the individuation question, and the persistence question – the article goes on to focus on the first: the question of which ontological category musical works fall under. The paper ends by introducing, and briefly considering, (...)
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  36. The Possibility of Profound Music.Julian Dodd - 2014 - British Journal of Aesthetics 54 (3):299-322.
    Peter Kivy has become convinced that it is impossible for pure, instrumental music to be profound. This is because he takes works of such music to be incapable of meeting what he claims to be two necessary conditions for artistic profundity: that the work denotes something profound, and that the work expresses profound propositions about its profound denotatum. The negative part of this paper argues as follows. Although works of pure, instrumental music do, indeed, fail to meet these conditions, the (...)
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  37. Defending musical platonism.Julian Dodd - 2002 - British Journal of Aesthetics 42 (4):380-402.
    This paper sees me clarify, elaborate, and defend the conclusions reached in my ‘Musical Works as Eternal Types’ in the wake of objections raised by Robert Howell, R. A. Sharpe, and Saam Trivedi. In particular, I claim that the thesis that musical works are discovered rather than created by their composers is obligatory once we commit ourselves to thinking of works of music as types, and once we properly understand the ontological nature of types and properties. The central argument of (...)
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  38.  28
    The Humanist Frame.Julian Huxley - 2018 - Franklin Classics.
    This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be (...)
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  39. An Embodied Predictive Processing Theory of Pain.Julian Kiverstein, Michael David Kirchhoff & Mick Thacker - 2022 - Review of Philosophy and Psychology 1 (1):1-26.
    This paper aims to provide a theoretical framework for explaining the subjective character of pain experience in terms of what we will call ‘embodied predictive processing’. The predictive processing (PP) theory is a family of views that take perception, action, emotion and cognition to all work together in the service of prediction error minimisation. In this paper we propose an embodied perspective on the PP theory we call the ‘embodied predictive processing (EPP) theory. The EPP theory proposes to explain pain (...)
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  40.  39
    What are the drivers of induction? Towards a Material Theory+.Julian Reiss - 2020 - Studies in History and Philosophy of Science Part A 83 (C):8-16.
  41.  57
    Working as Equals: Relational Egalitarianism and the Workplace.Julian David Jonker & Grant J. Rozeboom (eds.) - 2023 - New York, US: Oxford University Press USA.
    Are hierarchical arrangements in the workplace, including the employer-employee relationship, consistent with the ideal of relating to one another as moral equals? With this question at its core, this volume of essays by leading moral and political philosophers explores ideas about justice in the workplace, contributing to both political philosophy and business ethics. Relational egalitarians propose that the ideal of equality is primarily an ideal of social relationships and view the equality of social relationships as having priority over the distributive (...)
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  42.  91
    Types, Tokens, and Talk about Musical Works.Julian Dodd & Philip Letts - 2017 - Journal of Aesthetics and Art Criticism 75 (3):249-263.
    It has recently been suggested that the type/token theorist concerning musical works cannot come up with an adequate semantic theory of those sentences in which we purport to talk about such works. Specifically, it has been claimed that, since types are abstract entities, a type/token theorist can only account for the truth of sentences such as “The 1812 Overture is very loud” and “Bach's Two Part Invention in C has an F-sharp in its fourth measure” by adopting an untenable semantic (...)
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  43.  40
    Moving from ‘fully’ to ‘appropriately’ informed consent in genomics: The PROMICE framework.Julian J. Koplin, Christopher Gyngell, Julian Savulescu & Danya F. Vears - 2022 - Bioethics 36 (6):655-665.
    Genomic sequencing technologies (GS) pose novel challenges not seen in older genetic technologies, making traditional standards for fully informed consent difficult or impossible to meet. This is due to factors including the complexity of the test and the broad range of results it may identify. Meaningful informed consent is even more challenging to secure in contexts involving significant time constraints and emotional distress, such as when rapid genomic testing (RGS) is performed in neonatal intensive care units. In this article, we (...)
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  44. The Is/Ought Gap, the Fact/Value Distinction and the Naturalistic Fallacy.Julian Dodd & Suzanne Stern-Gillet - 1995 - Dialogue 34 (4):727-.
    For the last 40 years or so the is/ought gap, the fact/value distinction and the naturalistic fallacy have figured prominently in ethical debates. This longevity, however, has had an adverse side effect. So familiar have they become that they—and their respective rationales—have tended to become blurred. It is the purpose of this paper to explain why they should be kept distinct.
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  45.  11
    Absolute or Relative Motion? A Study From the Machian Point of View of the Discovery and the Structure of Dynamical Theories.Julian B. Barbour - 1988 - Cambridge University Press.
    This richly detailed biography captures both the personal life and the scientific career of Isaac Newton, presenting a fully rounded picture of Newton the man, the scientist, the philosopher, the theologian, and the public figure. Professor Westall treats all aspects of Newton's career, but his account centers on a full description of Newton's achievements in science. Thus the core of the work describes the development of the calculus, the experimentation that altered the direction of the science of optics, and especially (...)
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  46.  51
    Liberal Rationalism And Medical Decision‐making.Julian Savulescu - 1997 - Bioethics 11 (2):115–129.
    I contrast Robert Veatch's recent liberal vision of medical decision‐making with a more rationalist liberal model. According to Veatch, physicians are biased in their determination of what is in their patient's overall interests in favour of their medical interests. Because of the extent of this bias, we should abandon the practice of physicians offering what they guess to be the best treatment option. Patients should buddy up with physicians who share the same values —‘deep value pairing’. The goal of choice (...)
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  47. Assertion and Rejection.Julian J. Schlöder - 2022 - In Daniel Altshuler, Linguistics Meets Philosophy. New York, NY, USA: Cambridge University Press.
    I argue that rejection is a speech act that cannot be reduced to assertion. Adapting an argument by Huw Price, I conclude that rejection is best conceived of as the speech act that is used to register that some other speech act is (or would be) violating a rule of the conversation game. This can be naturally understood as registering *norm violations* where speech acts are characterised by their essential norms. However, I argue that rejection itself is not to be (...)
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  48.  32
    Billionaires in world politics: donors, governors, authorities.Julian Eckl & Klaus Dingwerth - 2022 - Journal of Global Ethics 18 (2):201-210.
    ABSTRACT Hägel’s book is timely. As economic inequality has been on the rise, the increasing number of billionaires and their political activities have come under public scrutiny. The book contributes to such scrutiny and allows to ask questions about responsibility, accountability, and legitimacy. It also adds to scholarship on individuals in world politics. Our comment provides a critical discussion of two specific aspects of Hägel’s analysis. First, we clarify that most of the book focuses on billionaires as transnational actors while (...)
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  49.  28
    (1 other version)The Routledge Handbook of Philosophy of Economics.Conrad Heilmann & Julian Reiss (eds.) - 2019 - Routledge.
    The most fundamental questions of economics are often philosophical in nature, and philosophers have, since the very beginning of Western philosophy, asked many questions that current observers would identify as economic. The Routledge Handbook of Philosophy of Economics is an outstanding reference source to the key topics, problems, and debates at the intersection of philosophical and economic inquiry.It captures this field of countless exciting interconnections, affinities, and opportunities for cross-fertilization. Comprising thirty-five chapters by a diverse team of contributors from all (...)
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  50.  53
    The proper place of values in the delivery of medicine.Julian Savulescu - 2007 - American Journal of Bioethics 7 (12):21 – 22.
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