BackgroundSubjective cognitive decline, non-amnestic mild cognitive impairment, and amnestic mild cognitive impairment are regarded to be at high risk of converting to Alzheimer’s disease. Amplitude of low-frequency fluctuations can reflect functional deterioration while diffusion tensor imaging is capable of detecting white matter integrity. Our study aimed to investigate the structural and functional alterations to further reveal convergence and divergence among SCD, naMCI, and aMCI and how these contribute to cognitive deterioration.MethodsWe analyzed ALFF under slow-4 and slow-5 bands and white matter (...) fiber integrity among normal controls, SCD, naMCI, and aMCI groups. Correlation analyses were further utilized among paired DTI alteration, ALFF deterioration, and cognitive decline.ResultsFor ALFF calculation, ascended ALFF values were detected in the lingual gyrus and superior frontal gyrus within SCD and naMCI patients, respectively. Descended ALFF values were presented mainly in the LING, SFG, middle frontal gyrus, and precuneus in aMCI patients compared to CN, SCD, and naMCI groups. For DTI analyses, white matter alterations were detected within the uncinate fasciculus in aMCI patients and within the superior longitudinal fasciculus in naMCI patients. SCD patients presented alterations in both fasciculi. Correlation analyses revealed that the majority of these structural and functional alterations were associated with complicated cognitive decline. Besides, UF alterations were correlated with ALFF deterioration in the SFG within aMCI patients.ConclusionsSCD shares structurally and functionally deteriorative characteristics with aMCI and naMCI, and tends to convert to either of them. Furthermore, abnormalities in white matter fibers may be the structural basis of abnormal brain activation in preclinical AD stages. Combined together, it suggests that structural and functional integration may characterize the preclinical AD progression. (shrink)

Carolina Sartorio has criticized the reasons-responsiveness theory of freedom for being inconsistent with the actual-sequence view motivated by the Frankfurt-style cases. Specifically, reasons-responsiveness conceived as a modal property does not pertain to the actual sequence of the agent's action and thereby it is irrelevant to the agent's freedom and moral responsibility. Call this the challenge of irrelevance. In this article, I present this challenge in a new way that overcomes certain limitations of Sartorio's argument. I argue that the root of (...) the challenge is that reasons-responsiveness as an unmanifested modal property seems to be nonexplanatory for the agent's action. I show that reasons-responsiveness theorists will confront this challenge even if they do not endorse the actual-sequence view. Finally, I deflate this challenge with David Lewis's model of causal explanation, showing that reasons-responsiveness is explanatory in virtue of providing information about the causal history of the agent's action. (shrink)

This article draws the attention of research managers and policy makers to the issue that to become a science power curtailing misconduct is the daunting challenge that emerging countries simply cannot ignore. Systematic and orchestrated efforts are needed to foster and institutionalize research integrity education among all stakeholders.

This study aims to provide an integrated perspective on job crafting and its antecedents through the exploration of the joint effects of individual-level and team-level job crafting on employee work engagement. Drawing on conservation of resources (COR) theory, we propose that engaging in job crafting behaviors is promoted by the presence of job-related resources. In turn, job crafting is expected to result in higher levels of work engagement. We expect this reasoning to hold for the individual as well as the (...) team/collective levels. The hypotheses were tested using data from 287 medical professionals from 21 hospital units of a Chinese public hospital. Findings from two-level Bayesian structural equation modeling supported the idea that at the individual level, individual job crafting behaviors partially mediated the relationship from individual resources to individual work engagement. Further, collective crafting mediated the relationship from team resources to individual work engagement. In addition, a positive cross-level relation between collective crafting and individual crafting was found. We conclude that stimulated by resources, both job crafting processes at the individual-level and team-level can promote individual work engagement in Chinese employees. (shrink)

BackgroundBilateral cerebral palsy is the most common type of CP in children and is often accompanied by different degrees of communication impairment. Several studies have attempted to identify children at high risk for communication impairment. However, most prediction factors are qualitative and subjective and may be influenced by rater bias. Individualized objective diagnostic and/or prediction methods are still lacking, and an effective method is urgently needed to guide clinical diagnosis and treatment. The aim of this study is to develop and (...) validate an objective, individual-based model for the prediction of communication impairment in children with BCP by the time they enter school.MethodsA multicenter prospective cohort study will be conducted in four Chinese hospitals. A total of 178 children with BCP will undergo advanced brain magnetic resonance imaging at baseline. At school entry, communication performance will be assessed by a communication function classification system. Three-quarters of children with BCP will be allocated as a training cohort, whereas the remaining children will be allocated as a test cohort. Multivariate lesion- and connectome-based approaches, which have shown good predictive ability of language performance in stroke patients, will be applied to extract features from MR images for each child with BCP. Multiple machine learning models using extracted features to predict communication impairment for each child with BCP will be constructed using data from the training cohort and externally validated using data from the test cohort. Prediction accuracy across models in the test cohort will be statistically compared.DiscussionThe findings of the study may lead to the development of several translational tools that can individually predict communication impairment in children newly diagnosed with BCP to ensure that these children receive early, targeted therapeutic intervention before they begin school.Trial registrationThe study has been registered with the Chinese Clinical Trial Registry. (shrink)

本书为大型资料汇编丛书"儒教资料类编"之第七辑.这一辑, 将在前几辑的基础上继续展示清代中后期, 主要是清末儒者的儒教意识. 本辑所要回答的, 还有所谓"儒学宗教化"问题. 一些学者认为, 儒教本来不是教, 是康有为要把它宗教化.

Background: As one of the main participants in health care, nurses are esteemed an important driving force for the vigorous health care development. Studies report that nurses’ proactive personality has positive effects on their job performance; however, this relationship acquires further understanding.Objective: A cross-sectional study was performed to explore the relationship between nurses’ proactive personality and job performance; the mediating role of nurses’ competency and work engagement in this relationship was also evaluated.Methods: The study was performed in a large third-degree (...) general hospital in October 2019, Xi’an, PR, China. A sample of 246 nurses participated in this cross-sectional study. Proactive personality was assessed with the Proactive Personality Questionnaire, job performance was assessed by Heilman three-item measurements, nurse competence was estimated with Nurse Competency Scale, and work engagement was assessed with the Utrecht Work Engagement Scale. The structural equation model was used to test the main hypotheses.Results: Structural equation model analysis revealed that work engagement partially mediated the association between proactive personality and job performance. The serial two-mediator model which was used to explore the association between proactive personality and job performance through competency and work engagement, in sequence, was demonstrated.Conclusion: This study demonstrates that work engagement partially mediated the association between nurses’ proactive personality and their job performance. The serial two-mediator model demonstrated that proactive personality was associated with job performance via competency and work engagement. This study also revealed the critical role of nursing managers in understanding the nurses’ proactive personality, which would facilitate them to enhance the latter’s competency and promote their work engagement. All these will in turn constantly improve the overall quality of nursing and advance professional development of nursing and benefits for patients. (shrink)

Confucian culture has always been the most glorious component of Chinese culture. Governing the mainstream world of China for more than two millennia, it has cast a profound and long-lasting influence on the way of thinking and cultural-psychological formation of the Chinese people. Confucianism emphasizes caring about others with benevolence and governing a state with ethics, reflecting the importance of moral principles for politics. “Ren” and “Li” are important parts of the core values of Confucianism, so analyzing the differences between (...) them and their evolution is of great significance for further understanding Confucian culture. This paper selected 132 classic Confucian works from SikuQuanshu, a large collection of books compiled during the Qianlong’s reign of the Qing Dynasty, to calculate the use of frequency of “Ren” and “Li” in those books by means of big data. Then the data was analyzed to show the development trajectory of “Ren” and “Li” from the Spring and Autumn period to the Qing Dynasty, providing a new perspective for the study of Confucian culture. The analysis result shows that from the Spring and Autumn period to the Qing Dynasty, both the frequencies of “Ren” and “Li” record a peak and a bottom: “Ren” has its peak in the Sui and Tang period while “Li” reaches its climax in the Wei and Jin period ; both “Ren” and “Li” hit their bottom during the Yuan Dynasty. The average frequency of “Li” is higher than that of “Ren” during most of the time. In general, “Li” is more frequently referred to in classic Confucian works than “Ren,” especially in those of the pre-Sui and Tang era. The An-Shi Disturbances in the Tang Dynasty may mark an important turning point for the frequencies of “Ren” and “Li” in classic Confucian works. (shrink)

Patients with Wilson’s disease suffer from prospective memory impairment, and some of patients develop cognitive impairment. However, very little is known about how brain structure and function changes effect PM in WD. Here, we employed multimodal neuroimaging data acquired from 22 WD patients and 26 healthy controls who underwent three-dimensional T1-weighted, diffusion tensor imaging, and resting state functional magnetic resonance imaging. We investigated gray matter volumes with voxel-based morphometry, DTI metrics using the fiber tractography method, and RS-fMRI using the seed-based (...) functional connectivity method. Compared with HC, WD patients showed GM volume reductions in the basal ganglia and occipital fusiform gyrus, as well as volume increase in the visual association cortex. Moreover, whiter matter tracks of WD were widely impaired in association and limbic fibers. WM tracks in association fibers are significant related to PM in WD patients. Relative to HC, WD patients showed that the visual association cortex functionally connects to the thalamus and hippocampus, which is associated with global cognitive function in patients with WD. Together, these findings suggested that PM impairment in WD may be modulated by aberrant WM in association fibers, and that GM volume changes in the association cortex has no direct effect on cognitive status, but indirectly affect global cognitive function by its aberrant functional connectivity in patients with WD. Our findings may provide a new window to further study how WD develops into cognitive impairment, and deepen our understanding of the cognitive status and neuropathology of WD. (shrink)

This study investigates the role of socially responsible management as a significant determining factor for employees’ morale engagement, employee vitality, and employee-based brand equity. Human resource management policies and strategies are important for addressing the interests of the employees and boosting the overall effectiveness of the organization. To examine this, this study analyzes the role of socially responsible management and organizational morality on EME with the mediation of EV. Also, the study examines the role of EME in EBBE. To conduct (...) this study, the data were obtained from 310 female employees working in software houses from home in China. The sampling technique used in the study is purposive sampling. A partial least square structural equation modeling technique is used to analyze the data of the study. The study found that socially responsible management has a positive effect on both EME and EV. The study also reveals that organizational morality has a positive impact on EME and consequently impacts the EBBE in a positive way. The results of the mediation analysis show that EV mediates the relationship between socially responsible management and EME. The study provides practical implications, explaining the strategies and policies that can be adopted by the HR department of the organization to boost employee interests. The study also provides some limitations and future recommendations, such as sample size, the context of the study, and adding new variables to the existing framework. (shrink)

Promoting civic engagement could be a way of strengthening the social solidarity of China's urban population. The drastic socio-economic changes resulting from recent economic reform are likely to have a deleterious effect on social solidarity. Based on a survey conducted in 2010 in the Southern China city of Xiamen, this paper examines a specific form of civic engagement – citizen cooperation – to resolve community problems, and assesses its relationship with social capital. The study reveals that discrepancies in the level (...) of civic engagement exist among urban residents and that inequality of social capital plays a significant role in these discrepancies. The findings suggest that such gaps could be addressed by increasing social capital, especially by expanding residents' personal community networks. (shrink)

In special application scenarios, such as portable anesthesia depth monitoring, portable emotional state recognition and portable sleep monitoring, electroencephalogram (EEG) signal acquisition equipment is required to be convenient and easy to use. It is difficult to remove electrooculogram (EOG) artifacts when the number of EEG acquisition channels is small, especially when the number of observed signals is less than that of the source signals, and the overcomplete problem will arise. The independent component analysis (ICA) algorithm commonly used for artifact removal (...) requires the number of basis vectors to be smaller than the dimension of the input data due to a set of standard orthonormal bases learned during the convergence process, so it cannot be used to solve the overcomplete problem. The empirical mode decomposition method decomposes the signal into several independent intrinsic mode functions so that the number of observed signals is more than that of the source signals, solving the overcomplete problem. However, when using this method to solve overcompleteness, the modal aliasing problem will arise, which is caused by abnormal events such as sharp signals, impulse interference, and noise. Aiming at the above problems, we propose a novel EEG artifact removal method based on discrete wavelet transform, complete empirical mode decomposition for adaptive noise (CEEMDAN) and ICA in this paper. First, the input signals are transformed by discrete wavelet (DWT), and then CEEMDAN is used to solve the overcomplete and mode aliasing problems, meeting the a priori conditions of the ICA algorithm. Finally, the components belonging to EOG artifacts are removed according to the sample entropy value of each independent component. Experiments show that this method can effectively remove EOG artifacts while solving the overcomplete and modal aliasing problems. (shrink)

Previous research has demonstrated that regular exercise modulates motor cortical plasticity and cognitive function, but the influence of short-term high-intensity interval training remains unclear. In the present study, the effect of short-term HIIT on neuroplasticity and executive function was assessed in 32 sedentary females. Half of the participants undertook 2 weeks of HIIT. Paired-pulse transcranial magnetic stimulation was used to measure motor cortical plasticity via short intracortical inhibition and intracortical facilitation. We further adapted the Stroop task using functional near-infrared spectroscopy (...) to evaluate executive function in the participants. The results indicated that, compared with the control group, the HIIT group exhibited decreased ICF. In the Stroop task, the HIIT group displayed greater activation in the left dorsolateral prefrontal cortex and left orbitofrontal cortex even though no significant difference in task performance was observed. These findings indicate that short-term HIIT may modulate motor cortical plasticity and executive function at the neural level. (shrink)

本书系统探讨陶行知的生活教育理论的形成、发展过程,它的基本思想、基本结构以及它的理论基础与现实意义,并说明它是20世纪中国教育史上的一项最宝贵的创造。.

We develop a series of small infinitary epistemic logics to study deductive inference involving intra-/interpersonal beliefs/knowledge such as common knowledge, common beliefs, and infinite regress of beliefs. Specifically, propositional epistemic logics GL are presented for ordinal α up to a given αo so that GL is finitary KDn with n agents and GL allows conjunctions of certain countably infinite formulae. GL is small in that the language is countable and can be constructive. The set of formulae Lα is increasing up (...) to α = ω but stops at ω We present Kripke-completeness for GL for each α ≤ ω, which is proved using the Rasiowa–Sikorski lemma and Tanaka–Ono lemma. GL has a sufficient expressive power to discuss intra-/interpersonal beliefs with infinite lengths. As applications, we discuss the explicit definability of Axioms T, 4, 5, and of common knowledge in GL Also, we discuss the rationalizability concept in game theory in our framework. We evaluate where these discussions are done in the series GL, α ≤ ω. (shrink)

Our prior research demonstrated that the right temporoparietal junction exerted a modulatory role in ingroup bias in emotional mimicry. In this study, two experiments were conducted to further explore whether the rTPJ is a neural region for emotional mimicry or for the modulation of emotional mimicry by group membership in a sham-controlled, double-blinded, between-subject design. Both experiments employed non-invasive transcranial direct current stimulation to temporarily change the cortical excitability over the rTPJ and facial electromyography to measure facial muscle activations as (...) an index of emotional mimicry. After the anodal or sham stimulation, participants in Experiment 1 passively viewed a series of happy clips, while participants in Experiment 2 viewed happy clips performed by ethnic ingroup and outgroup models. fEMG analyses revealed that participants in Experiment 1 showed the same degree of happy mimicry for both tDCS conditions and participants in Experiment 2 showed an ingroup bias in happy mimicry in the sham condition, which disappeared in the anodal condition. Taken together, the present study demonstrated that rTPJ plays a role in the modulation of emotional mimicry by group membership. (shrink)

Martin Honecker, Hauptherausgeber des Evangelischen Soziallexikons, hat in besonderem Masse zur Profilierung der Evangelischen Soziallehre in der Zeit zwischen 1970 und 2000 beigetragen. In diesem Band soll die geschichtliche Entwicklung der Sozialethik dieser Zeit in den Blick genommen werden, es soll aber auch gefragt werden, welche Herausforderungen sich mittlerweile - insbesondere angesichts des gegenwartigen theologisch-sozialethischen Diskurses - fur die Aufgabenfelder einer Evangelischen Soziallehre ergeben.Eroffnet wird der Band mit einem ausfuhrlichen Interview mit Martin Honecker zur Genese seiner sozialethischen Position. Es folgen (...) Beitrage zu zentralen Themen heutiger Sozialethik. Schliesslich erfolgt eine Wurdigung des theologisch-sozialethischen Ansatzes Martin Honeckers unter Einbeziehung einer vollstandigen Liste seiner Veroffentlichungen. (shrink)

Social behavior is closely linked to self-efficacy, which is the individual’s confidence or belief that they can successfully complete a task in a given situation. The advent of social media classified social behavior as online and offline sociality, and has cultivated inconsistency in online and offline social behavior of university students, an issue that has come to prominence in scholarly research. However, the relationship between this inconsistency and self-efficacy is worthy of investigation because this particular confluence of behavioral concepts has (...) been rarely been researched. In this paper, online and offline social behavior is integrated, a typology for university student social activities established, and the correlation between different types of social activity and student self-efficacy investigated, with a specific focus on those with notable inconsistencies in their social performance. The following findings are reported. First, as online social networking has become the dominant form of social interaction, the types of social activity have increased, with one-third of university students showing inconsistent online and offline social behavior. However, different types of social activities have varied effects on the self-efficacy of university students, with differences between general self-efficacy, which is significantly above academic self-efficacy, and social self-efficacy. These effects are also different for students with inconsistent online and offline social performance; those who are active online show higher self-efficacy than those who are active offline. This study shows online social network interactions to be more closely related to student self-efficacy than offline interactions. (shrink)

Focusing on Hangzhou, a famous tourist city in China, in this study, four regression models were constructed through four items of tourist loyalty to investigate the influence of tourist perceptions and characteristics on male and female tourist loyalty to shared bicycles. A questionnaire survey and ordered logistic regression model techniques were used. Survey data from 467 tourists indicated that there were significant differences between male and female tourists. For male tourists, their willingness to reuse shared bicycles was positively correlated with (...) ease of access to cycles, environmental awareness, psychological benefit, and management provision; however, their willingness to recommend shared bicycles was only affected by environmental awareness, psychological benefit, and management provision. Among female tourists, willingness to reuse shared bicycles was affected by ease of access to cycles, environmental awareness, and rule adherence, while their willingness to recommend shared bicycles was affected by ease of access to cycles, environmental awareness, psychological benefit, and managerial provision. In addition, female tourists’ socio-demographic and behavioral characteristics had a significant impact on their loyalty, among which length of stay in Hangzhou and education were significant in the four regression models, and number of visits to Hangzhou had a positive impact on female tourists’ willingness to reuse. In addition, female tourists who used Hellobike had higher willingness to reuse and recommend than those who used Mobike. For male tourists, only length of stay in Hangzhou had a significant impact on their reuse intention. The current study extends the theory of attribution to explore the factors which may affect tourist’s loyalty to bicycle-sharing from the perspectives of tourists’ perceptions. It will provide further support to decision makers in the development of new shared-bicycle systems at Chinese tourist destinations, with the aim of strengthening tourist loyalty to shared-bicycle programs. (shrink)

This chapter contains section titled: Literary Revolution and its Meaning The Naturalistic Conception of the Universe and the Experimentalist Method History of Chinese Philosophy and Systematizing the National Heritage Political Philosophy and Liberalism Hu Shi as an Enlightenment Philosopher.