Analysis of sites of newly integrated DNA in cellular genomes is important to several fields, but methods for analyzing and visualizing these datasets are still under development. Here, we describe tools for data analysis and visualization that take as input integration site data from our INSPIIRED pipeline. Paired-end sequencing allows inference of the numbers of transduced cells as well as the distributions of integration sites in target genomes. We present interactive heatmaps that allow comparison of distributions of integration sites to (...) genomic features and that support numerous user-defined statistical tests. To summarize integration site data from human gene therapy samples, we developed a reproducible report format that catalogs sample population structure, longitudinal dynamics, and integration frequency near cancer-associated genes. We also introduce a novel summary statistic, the UC50, which provides a single number summarizing possible clonal expansion. Using these tools, we characterize ongoing longitudinal characterization of a patient from the first trial to treat severe combined immunodeficiency-X1, showing successful reconstitution for 15 years accompanied by persistence of a cell clone with an integration site near the cancer-associated gene CCND2. Software is available at https://github.com/BushmanLab/INSPIIRED. (shrink)

Paul Weiss continues the brilliant analysis of art he began in _The World of Art _and _Nine Basic Arts_—here_ _in the medium of film, at which he takes a close and inde­pendent look. Writing in a vigorous, jargon-free style, and covering all aspects of films and film making, Mr. Weiss presents a fresh, new approach to the study of our newest art. During the course of writing _Cinematics_,_ _Mr. Weiss asked various writers, critics, scholars, and producers long involved with film (...) to read and remark on what he had written. Five of them—Eric Sherman, Joseph Williman, Arthur Knight, David Slavitt, and Robert Thom—provided comments which are incorporated in the text. Their remarks are often trenchant, and perceptively provocative. These men frequently comment on lines of inquiry suggested in the book and often take issue with what has been said. The result is a kind of dialogue crisscrossed with stimu­lating insights. While this book is aimed at the general reader, Mr. Weiss hopes that experts and practitioners of film making will benefit from this fresh, independent, and philo­sophically based inquiry. Readers already familiar with Mr. Weiss’s writings will delight in this distillation of his thought on an art so intimately a part of our cul­ture. (shrink)

This book is the first to offer a detailed analysis of Aristotelian and Kantian ethics together, in a way that remains faithful to the texts and responsive to debates in contemporary ethics. Recent moral philosophy has seen a revival of interest in the concept of virtue, and with it a reassessment of the role of virtue in the work of Aristotle and Kant. This book brings that re-assessment to a new level of sophistication. Nancy Sherman argues that Kant preserves (...) a notion of virtue in his moral theory that bears recognisable traces of the Aristotelian and Stoic traditions, and that his complex anthropology of morals brings him into surprising alliance with Aristotle. She develops her argument through close readings of major texts by both Aristotle and Kant, illustrating points of congruence and contrast. (shrink)

A deeply informed exploration of what Stoic ideas have to offer us today Stoicism is the ideal philosophy of life for those seeking calm in times of stress and uncertainty. For many, it has become the new Zen, with meditation techniques that help us face whatever life throws our way. Indeed, the Stoics address a key question of our time: how can we be masters of our fate when the outside world threatens to unmoor our well-being? In Stoic Wisdom, Georgetown (...) philosophy professor Nancy Sherman, an expert in ancient and modern ethics, shows what a practical modern Stoicism really looks like. Drawing on the wisdom of Stoic thinkers Epictetus, Marcus Aurelius, Seneca and others, Sherman paints a portrait that uncovers the true subtlety and power of Stoic ideas. That portrait reveals a truth often ignored: that the Stoics never thought self-sufficiency was only about rugged self-reliance and mental discipline. We are at home in the world, they taught, when we are connected to each other in cooperative efforts. While mastery of one's self is essential, we also must draw on our deepest relationships for true strength and resilience. Bringing these ancient ideas to bear on 21st century environments-from Silicon Valley to first responders in a pandemic, to soldiers on the battlefield-Sherman shows how Stoicism can both prepare us for an uncertain future and help us cope with traumatic events. Stoic Wisdom will appeal to anyone feeling helpless or looking for deeper, meaningful strength and goodness in addressing life's biggest and smallest challenges. (shrink)

Drawing on in-depth interviews with service women and men, Nancy Sherman weaves narrative with a philosophical and psychological analysis of the moral and emotional attitudes at the heart of the afterwars. Afterwar offers no easy answers for reintegration. It insists that we widen the scope of veteran outreach to engaged, one-on-one relationships with veterans.

John Hawthorne’s marvelous book contains a wealth of arguments and insights based on an impressive knowledge and understanding of contemporary discussion. We can address only a small aspect of the topic. In particular, we will offer our own answers to two questions about knowledge that he discusses.

Annotation Eric Voegelin (1901-1985) was one of the most original and influential philosophers of our time. Born in Cologne, Germany, he studied at the University of Vienna, where he became a professor of political science in the Faculty of Law. In 1938, he and his wife, fleeing Hitler, immigrated to the United States. They became American citizens in 1944. Voegelin spent much of his career at Louisiana State University, the University of Munich, and the Hoover Institution at Stanford University. (...) During his lifetime he published many books and more than one hundred articles. The Collected Works of Eric Voegelin will make available in a uniform edition all of Voegelin's major writings. (shrink)

Graphical Abstract2015 marks the centennial of the discovery of bacteriophages, viruses that infect bacteria. Phages have been central to some of biology's most meaningful advances over the past hundred years (shown here); they greatly influence the workings of the biosphere, and are poised to play expanded roles in biomedicine, biotechnology, and ecology.

Augustin a commencé de s'intéresser aux questions de l'âme, de sa nature, de son origine et de son destin sous le double horizon des croyances manichéennes, auxquelles le tenait attaché son obsession du problème du mal et du salut, et des doctrines néoplatoniciennes, en qui il trouvait une certaine parenté avec la spiritualité chrétienne. Le néoplatonisme l'aidait à concevoir l'immortalité de l'âme, mais en rejetant sa consubstantialité avec Dieu, à écarter aussi le dualisme manichéen tout en professant la dualité ontologique (...) de Dieu et du créé, et de l’âme et du corps. Mais l'Écriture se dissocie du platonisme quand elle montre que l'âme ne peut pas remonter par ses seules forces jusqu'au vrai et au bien et qu'elle a besoin du secours de la grâce et des sacrements. L'Écriture érige des réalités d'ordre sotériologique étrangères aux spéculations des philosophes, elle fait du péché une réalité originelle et universelle, dont la transmission relance la question de l'origine des âmes : préexistantes, ou créées à la naissance ou issues de celles des parents ? Augustin noue ainsi l'une à l'autre les deux questions de l'origine du mal et de celle de l'âme, notamment dans le troisième livre du traité Du libre arbitre, entre 391 et 395. Il pense que ni l'Écriture ni la philosophie ne permettent de trancher entre le créationisme et le traducianisme, mais il s'efforce de concilier, sans y parvenir tout à fait, le plan anthropologique avec le plan sotériologique. Augustine began his interest in the nature, origin, and destiny of the soul under the double influence of Manichaean beliefs , and Neoplatonic doctrines, in which be found a certain relation with Christian spirituality. Neoplatonism helped him to conceive the immortality of the soul, but by rejecting its consubstantiality with God, and also to set aside Manichaean dualism while professing the ontological duality of God and the created, as well as the soul and body. But Scripture disassociates itself from Platonism when it shows that the soul cannot, by its own power, arise to the true and the good, but needs help from grace and the sacraments. Scripture builds its realities around soteriology, which is foreign to the speculations of philosophers. It makes sin an original and universal reality, whose transmission brings up again the origin of souls : pre-existent, created at birth, or issuing from those of its parents ? Augustine thus ties together the two questions of the origin of evil and that of souls, especially in the third book of the treatise On Free Will . He thought that neither Scripture nor philosophy helped to decide for creationism and traducianism, but he made an effort to reconcile, without complete success, the anthropological dimension with the soteriological dimension. (shrink)

Cette étude met en évidence la spécificité et l'évolution de la philosophie de Natorp (1854-1924). Sa psychologie critique est d'abord une méthodologie s'interrogeant sur les conditions d'une connaissance scientifique des processus cognitifs. Puis Natorp en vient à considérer dans ses derniers textes que la question fondamentale est celle de l'être.

Researches conducted so far within the project Spinning out of control: rhetoric and violent conflict. Representations of 'self' - 'other' in the Yugoslav successor states focused on exploring the relations towards the Other in a state of conflict. Moreover: most of the author's and coauthors' contributions were oriented towards discourse analysis in the context of violence. Except for the peaceful dismemberment of Montenegro and Serbia, proclamation of independence of other Yugoslav states did not go without violence, to a greater or (...) lesser extent. The Other in these situations was predominantly the ethnic Other, and usually treated as enemy. For that reason, the greater part of our past work was oriented towards analysing media reports of the most stiking war events. Also, some of the contributions intentionally targeted media reportings of tense situations and those bearing the unpredictable outcomes, such as referenda or meetings discussing war and peace matters; or, we focused our inquiries on radical standpoints expressed by certain media or political parties - all that in order to explore the essencial forms of constructing and manifesting the Otherness on a rhetoric level. From a broader perspective, the analysed period, marked by the wars of ex - Yugoslavia in the last decade of 20th century, could be comprehended as the preiod of a state of emergency, where the old order had been brutally and radically destroyed and the new one was installed. In such a process, as it was shown, the relation towards the Other was also usually extreme and ethnically motivated. Now, after the constitution of seven new states where once former Yugoslavia was, new questions emerge. We are interested, as we were before, in the identity constructions, especially in the relations toward the Other, and Otherness in general, now in the period of transition and normalization of mutual relationships that these societies are undergoing. Along with the theories of ethnicity and identity construction, the key perspective remains discursive analysis. Our main question is What is happening with the phenomenon of Otherness in public discourse, in the peaceful times, or in the post conflict state? Do the ways of representing Others from the conflict times disappear, or do they 'freeze', that is to say, remain the same, or get manifested on some other levels and by different rhetorical tools? In short, what is happening with the Others in discourses that do not 'spin out of control'? Are the Others stable, mutable or flexible category and where are the imagological boundaries of Otherness? Who are the Others now? Are there any Others among us in ethnical sense? What is the nature of relation towards the common Yugoslav past, in other words, has the common past also become the Otherness for the people of former Yugoslavia? Are the 'refugees', 'cast-outs', 'displaced persons', 'returnees'... only the new names for the old display of Otherness? (shrink)

The essay considers contemporary surveillance strategies from a Christian ethical perspective. It discusses first surveillance as a form of speech in the light of biblical themes of truthfulness, then draws on principles of subsidiarity and solidarity. Surveillance is dignified as human work whilst its dehumanizing outcomes are challenged. It is concluded that surveillance must contribute to human dignity and that accountability for data must follow a revised model of subsidiarity, appropriate to network rather than linear socio-political relationships. Mutual responsibility for (...) one another's data-image is derived from solidarity which, further, offers a response to the angst of a culture of suspicion. (shrink)

Renaud Barbaras wants to show that only the concept of life can help us understand how the subject may be a condition as well as a part of the world. The failures of the former phenomenological theories on this point is due to “the ontology of death” they assume, which leads to separate the conscience and the body. It is thus required to realise an epochè of death so as to think the unity of the subject. Ultimately, Renaud Barbaras is (...) led to define life from desire. (shrink)

Drama is ingedikt conflict, meent Eric Schneider. Toch schonk één rol, gespeeld door één actrice, hem hoop en vertroosting.

The ideas of the German philosopher Martin Heidegger have been described as an intellectual time bomb, as some of the most revolutionary thought in western history. Despite the enormous amount of secondary scholarship available on Heidegger, it is–due to the complexity of his thought and the density of his writing–difficult for the curious beginner to gain an insight into Heidegger’s philosophy. Heidegger For Beginners serves as an entry into the ideas of one of the 20th century’s most important thinkers, situating (...) Heidegger’s thought within its philosophical and historical context–alongside such thinkers as Plato, Descartes, Kant, Nietzsche, Husserl and Sartre. Heidegger For Beginners explicates many of Heidegger’s central ideas, including the Nothing , average everydayness, care, existence, be-in-the-world, the One , the critique of technology, anxiety, and most importantly, Being –a notion which may offer us the key to understanding the very mystery of our own existence. (shrink)

Le présent article s’attache à reconstruire le concept de réseau tel qu’il apparaît aux différents étages de la pensée pluridisciplinaire d’Edgar Morin. Le projet qu’il engage autour de la complexité dans La Méthode impose au préalable de renoncer, sur le plan épistémologique, à la conception disjonctive dominante de la connaissance au profit d’un ordre plus réticulaire des sciences. Le réseau est par la suite entendu comme un mode d’organisation particulier qui, valant pour le monde physique, est alors décliné, dans les (...) mêmes termes, sur le vivant et le social. Articulée autour des idées de « société-cerveau » et d’« individu clignotant », la sociologie du réseau que Morin développe pour suivre l’évolution sociale vers la complexité, le conduit à une analyse de la mondialisation dont il dégage le paradoxe inquiétant de son état d’inachèvement actuel.This article attempts to reconstruct the network concept as it appears in various stages of thinking multidisciplinary Edgar Morin. The project he undertakes around the complexity Method requires the prior waive the epistemological dominant design disjunctive knowledge in favor of a more reticular science. The network is then understood as a particular form of organization which, being valid for the physical world, then declined in the same terms, the living and the social. Built around the ideas of "society-brain" and "self flashing" sociology of the network develops Morin to monitor social complexity to the analysis led to a globalization which releases the disturbing paradox of current state of incompletion. (shrink)

This essay sketches the musical art of Frances Pelton-Jones, an American harpsichordist active at the beginning of the twentieth century. Almost entirely unknown today, she was widely acclaimed in her day for performing elaborate costume recitals dressed as Marie Antoinette. More than just a recitalist in costume, Pelton-Jones staged elaborate tableaux vivants with environmental decor to elicit fantasies of the past. Bridging the worlds of fashion, environmental design, and music, her performances offer a compelling case study to investigate the aesthetic (...) applications of Jane Bennett’s ecological theory of assemblages. Exploring how different human and nonhuman actants collaborated in Pelton-Jones’ art to evoke whole historical atmospheres for her audiences, I elaborate Bennett’s argument about the synthetic potential of combining certain materials to conjure an affect, highlighting how the delicacy of the assemblage as a whole often is contingent upon the frailty of the individual materials involved. Ultimately, Bennett’s theory affirms the aesthetic sensibilities of Pelton-Jones whose musical productions delighted audiences by harnessing the synthetic potential of well-coordinated vital materials. (shrink)

In Keeping Your Ethical Edge Sharp, Doug Sherman and Bill Hendricks discuss the critical issues that confront us in the workplace--possibly our most strategic sphere of influence today. They point put the obstacles that often keep our lights from shining in the darkness, and they present six principles we must be mindful of if we're to keep our ethical edge sharp and our witness distinctive.

Exploring the meeting of mystical and philosophical theology, Partakers of the Divine shows that Christian philosophical and contemplative practices arose together and that throughout much of Christian history, philosophy, theology and contemplation remained internal to one another. In this compelling volume, Jacob Holsinger Sherman demonstrates that the relation of philosophy, theology and contemplation to one another provides theologians and philosophers of religion today with a way forward beyond many of the stalemates that have beset discussions about faith and reason, (...) the role of religion in contemporary culture, and the challenges of modernity and postmodernity"--Page 4 of cover. (shrink)

Abstract:This essay explores key values of John Lachs's work, especially freedom, diversity, and human flourishing, when applied to the history of the philosophy of education as well as to the practical problems of policy and implementation today in American schools. I consider the importance and tensions involved in these values in the thinking of Plato, Jean-Jacques Rousseau, and John Dewey. Next, I examine necessary and then avoidable challenges of operationalizing freedom and diversity in schools, especially in tensions with recent policy (...) initiatives that threaten freedom and diversity for human flourishing. The aim here is to note the central importance of the values that Lachs has long championed, while attending also to the risks and dangers that misunderstanding and narrow thinking pose about them when applied to American public schools. Ultimately, I argue that while advocacy for liberty sometimes raises profound problems in the sphere of public education, democratic education is enriched immeasurably when it enables and empowers freedom to pursue diverse forms of flourishing. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Ideas 62.4 (2001) 651-664 [Access article in PDF] Walter Charleton and Early Modern Eclecticism Eric Lewis The publication of Michael Albrecht's Eklektik (1994) revived a small amount of scholarly interest in an early modern "movement" with a lineage that can be traced back to Clement of Alexandria, who described a method of constructing a philosophical system by selecting among different philosophical sects. 1 (...) Not surprisingly, the reception of Albrecht's work demonstrated the complexities associated with identifying the "movement" and categorizing those who labeled themselves "eclectic" philosophers; that is, those who seemed to expound a system of philosophy assimilated from ancient and modern sources. The difficulties involved with defining "eclecticism" and applying the term to early modern natural science is further complicated by the tendency for "eclectics" to categorize their contemporaries in ways that are counterintuitive to our modern sensibilities. 2 Nevertheless, the proponents of this patchwork style of natural science are interesting precisely because they give us a glimpse into their interpretation of the state of philosophy and its relation to history during a time when the authority of The Philosopher was falling under ever increasing scrutiny.The recent literature on philosophic eclecticism largely ignored the English context where rising sentiment against sectarianism influenced the formation of the Royal Society. 3 The perceived chaos of a nation divided and redivided by the multiplication of religious associations produced a plethora of proposals for the restoration and maintenance of intellectual and social order. In particular the problems of religious and political order motivated certain members of the [End Page 651] "Newcastle Circle" (largely Royalists) to construct philosophical methodologies at least congruent with their ideological commitments to social stability. Thomas Hobbes, Margaret Cavendish, and her close friend the physician Walter Charleton each offered his and her own style of natural science. 4 Both Hobbes and the Duchess of Newcastle were excluded from participating in the community of natural philosophers formed in 1660; yet Charleton became a founding member of the Royal Society that year. Despite relative neglect, Charleton's importance to understanding the development of modern natural science in England should not be overlooked; and particularly his prescribed method of doing natural philosophy needs more attention. 5 Like the radically different methods developed by Margaret Cavendish and Thomas Hobbes, Charleton's eclecticism should be viewed as an exhaustive effort to prescribe a remedy to the perceived threat of rampant sectarianism. 6 Unlike Hobbes and Cavendish, however, Charleton saw authoritarianism and dogmatism as the greatest challenge to order, and found the solution to that challenge in mitigated skepticism and a style of philosophy that did not make an epistemic differentiation between the novel philosophies of his day and those of the ancients.Despite being a prolific writer, having a considerable reputation as a physician and placing himself in the center of the English community of natural scientists, Walter Charleton has been mostly ignored by modern scholars. In part this lack of attention can be attributed to the common view that he never developed a comprehensive philosophy nor maintained consistent metaphysical commitments. References to him claim that he was an "intellectual barometer of the age," 7 and his work has been described as "important as a case study in the reception of a mechanical philosophy." 8 His name is virtually absent from discussions concerning scientific methodology, though he is often described as a Renaissance [End Page 652] alchemical philosopher who fell under the influence of mechanistic atomism and the experimental agenda of a fledgling society of natural philosophers. Most accounts simply portray Charleton as a converted follower of the novel philosophy rather than as a novel thinker.The failure to see Charleton as more than a converted empiricist and mechanist likely results from the opinion that eclecticism does not constitute a philosophical method as much as it constitutes the last refuge for scholars during periods of intellectual crisis. The article on eclecticism in Encyclopedia Britannica (fourteenth edition) states: Eclecticism always tends to spring up after a period of vigorous constructive speculation, especially in the later stages of a controversy between... (shrink)

In _The New Order and Last Orientation,_ Eric Voegelin explores two distinctly different yet equally important aspects of modernity. He begins by offering a vivid account of the political situation in seventeenth-century Europe after the decline of the church and the passing of the empire. Voegelin shows how the intellectual and political disorder of the period was met by such seemingly disparate responses as Grotius's theory of natural right, Hobbes's _Leviathan,_ the role of the Fronde in the formation of (...) the French national state, Spinoza's _Tractatus Theologico-Politicus,_ and Locke's _Second Treatise,_ the blueprint of a modern middle-class society. By putting these responses and the thought of Montesquieu, Hume, and others in the context of the birth pains of the national state and the emergence of a new self-understanding of man, Voegelin achieves a brilliant mixture of political history and profound philosophical analysis. Voegelin's verdict of modernity is pronounced most powerfully in the opening part of "Last Orientation," in the chapter entitled "Phenomenalism." His discussion of the intellectual confusion underlying the modern project of scientistic phenomenalism is the most original criticism leveled against modernity to date. It is at the same time the first step toward a recovery of reality through philosophy conceived as a science of substance in the spirit of Giordano Bruno. Voegelin's first example of such an effort at recovering reality is the chapter on Schelling, one of the spiritual realists who has not been affected by the prevailing rationalist or reductionist creeds that are part of the modern disorder. Schelling's indirect yet powerful influence on Schopenhauer, Nietzsche, and Freud more than justifies Voegelin's interest in his philosophy and character, even though Voegelin would later distance himself from some of Schelling's positions. The volume's concluding chapter, "Nietzsche and Pascal," applies the understanding gained from the study of Schelling to the thought of the most powerful critic of the age, Nietzsche. Nietzsche's self-avowed affinity with Pascal provides the key to an analysis of the strengths and weaknesses of his thought and reaffirms the connection that links the beginning of modernity with its most recent crises and the efforts to overcome them. (shrink)

Interprétant l’histoire de l’humanité comme la suite discontinue dans le temps des différents degrés d’ouverture de l’âme humaine au mystère du fondement de l’être, Eric Voegelin a cherché à rompre avec toutes les visions unilinéaires de l’histoire qui ont caractérisé la pensée occidentale depuis le XVIIIe siècle et ont constitué une forme désastreuse d’impérialisme spirituel. En 1970, le philosophe a voulu rendre explicites les principes de sa démarche dans un article intitulé « Equivalences of experience and symbolisation in history (...) ». C’est ce texte qui est ici traduit en français pour la première fois.Les équivalences de l’expérience et de la symbolisation dans l’histoire Interpreting the history of mankind as the discontinued temporal succession of the various degrees of openness of the human soul to the mystery of the ground of being, Eric Voegelin has tried to break with all the one-line histories, characteristic of the Western thought since the eighteenth century and forming a disastrous kind of spiritual imperialism. In 1970, the philosopher wanted to clarify the principles of his thought processes in an article entitled « Equivalences of experience and symbolisation in history ». This text is translated here in French for the first time. (shrink)

In his review on Leo Strauss’ «On tyranny» Eric Voegelin, pointing out importance of his opponent’s work, still disagrees with several crucial Strauss’s findings. Especially important for him is comparing of «ancient» and «modern» tyranny, as well as Strauss’ idea that the text of «Hiero» makes up bounds between ancient and modern political philosophy, «tyrannical teaching» of Xenophon, the author of «Hiero», is very close to the Machiavelli’s point of view as presented in «The Prince». Voegelin points out that (...) this thought is indeed not that true and Machiavelli’s teaching does deal with the same sort of problem as Xenophon’s writing, because these texts were created in different historical contexts. The main aim is to understand modern tyranny, but, Voegelin argues, it won’t happen if we, as Strauss does, think that ancient and modern tyranny are the same. (shrink)

This volume contains the most significant pieces of unpublished writing completed by Eric Voegelin during an important time of his career.

In Morality, Leadership, and Public Policy, Eric Weber argues for an experimentalist approach to moral theory in addressing practical problems in public policy. The experimentalist approach begins moral inquiry by examining public problems and then makes use of the tools of philosophy and intelligent inquiry to alleviate them. -/- Part I surveys the uses of practical philosophy and answers criticisms - including religious challenges - of the approach, presenting a number of areas in which philosophers' intellectual efforts can prove (...) valuable for resolving public conflicts. -/- Part II presents a new approach to experimentalism in moral theory, based on the insights of John Dewey's pragmatism. Focusing on the elements of good public inquiry and the experimentalist attitude, Weber discusses ways of thinking about the effective construction and reconstruction of particular problems, including practical problems of public policy prioritization. -/- Finally, in Part III the book examines real-world examples in which the experimentalist approach to ethics proves useful, including instances of "bandwidth theft" and the controversies surrounding activist judges in the US Supreme Court. (shrink)

Autant d'études classiques qui accompagnent les grands ouvrages d'Eric Weil, Logique de la philosophie, Philosophie morale, Philosophie politique.

This paper argues that the classification of propositional attitudes into the de re, de dicto, and de se is incomplete. De se attitudes are widely agreed to be closely connected to de re attitudes. But there is a species of belief that is linked to agent-centered action in the way that de se beliefs are, but is also associated with entities, places, and especially times, under a description. These mark out a fourth kind. One way to think about what makes (...) them distinctive is that, despite being ‘essentially indexical’ they can be retained across different contexts of evaluation without having diagonal content. The paper also discusses the connection between such beliefs and the kinds of utterances (like ‘Don't put off for tomorrow what you can do today’) that are contested as examples of what David Kaplan called ‘monsters.’. (shrink)