Tasavvuf tarihinin tesirleri çağları aşan sûfîlerinden biri olan Hallâc-ı Mansûr, ileri sürdüğü fikirleri, ortaya koyduğu sıra dışı sûfîlik tavrı ve trajik ölümü ile büyük bir şöhret kazanmıştır. O, farklı sahalara mensup birçok ilim vefikir adamının dikkatiniçekmiş, bunlardan bazılarının ağıreleştirilerine maruz kalırken, pek çoğunun da takdirlerini kazanmıştır. Söz konusu eleştiri ve takdire tasavvuf ehli içinden gelen örneklerin sayısı ise dikkat çekici ölçüde fazladır. Hallâc’ın yaşadığı dönemde ona methiyelerde bulunan ve onu tenkit eden sûfîler olduğu gibi, o, ölümünün ardından da birçok mutasavvıftan (...) övgü ve tenkit almıştır. Bu makalede, Hallâc’ın tasavvufî görüşleri ve sûfî kişiliği hakkında onun çağdaşlarından 14. yüzyıla kadar olan bazı mutasavvıfların övgüleri ve yergileri ele alınacak, onun tasavvuf ehli üzerindeki tesirlerine sadece bu bağlamda ışık tutulmaya çalışılacaktır. (shrink)

Esta edição contém a única transcrição estudantil sobrevivente das Lições de Metafísica de Kant da década de 1770. A Lição foi ministrada o mais tardar no inverno de 1779/80 e, portanto, antes mesmo da publicação da Crítica da Razão Pura (1781). Um exceção é, contudo, a parte sobre a ontologia que seguramente se remonta a uma Lição que Kant ministrou depois de 1781. Estas transcrições de Lições são de valor inestimável para a história do desenvolvimento da filosofia de Kant e, (...) em especial, para a gênese de sua Crítica da Razão Pura . Elas representam também um complemento importante para suas outras Lições, como por exemplo, as de antropologia, nas quais Kant também se ocupou com as questões da psicologia empírica e racional. É interessante observar que Kant se serve de métodos distintos, nas Lições de Antropologia e de Metafísica, para demonstrar a substancialidade e a imortalidade da alma. Embora Kant ainda leve a doutrina da alma da psicologia racional muito a sério na Metafísica-Pölitz, ele rejeitará de fato suas pretensões de conhecimento pouco tempo depois na Crítica na seção sobre os paralogismos da doutrina pura da alma. Aquele que deseja se aprofundar na filosofia de Kant e conhecer seu contexto histórico-filosófico não pode deixar de ler as Lições de Metafísica-Pölitz. Heiner F. Klemme Martin-Luther-Universität Halle-Wittenberg. (shrink)

No centro da filosofia moral de Kant está sem dúvida sua doutrina do imperativo categórico. Por esse motivo não é de se surpreender que a Fundamentação da Metafísica dos Costumes (1785), na qual Kant explica, em detalhes, essa doutrina pela primeira vez, tenha sido o foco da atenção por décadas. Mas há alguns anos é observável uma significativa mudança na literatura que é univocamente bem vinda: ao lado da pesquisa das Doutrinas da Virtude e do Direito publicadas por Kant nos (...) anos noventa do século 18, agora também são intensamente estudadas suas perspectivas filosófico-morais desenvolvidas antes de 1781. Nesse sentido assume uma posição de destaque o manuscrito estudantil de uma lição de ética ministrada no meio dos anos 70, que é publicada aqui, em língua portuguesa, pela primeira vez em uma tradução comentada. Ainda hoje, esta lição serve como uma introdução à ética de Kant, muito embora pareça divergir, em alguns aspectos, da doutrina crítica do imperativo categórico. As Lições de Ética são um „trabalho em andamento“. Por um lado, somos capazes de assistir Kant "pensando" e compreender como ele se reporta ao livro de Alexander Baumgarten sobre os Príncípios da Metafísica Prática (Initia philosophiae practicae primae, 1760). E, por outro lado, somos capazes de vivenciar como ele desenvolve suas próprias perspectivas filosófico-morais em contraste a Baumgarten. Para todos que se interessam pela filosofia moral de Kant e pela história da ética na época da Aufklärung, o estudo desse manuscrito é indispensável. -/- Heiner F. Klemme (Martin Luther Universität - Halle-Wittenberg) . (shrink)

The evolution of sex in eukaryotes represents a paradox, given the “twofold” fitness cost it incurs. We hypothesize that the mutational dynamics of the mitochondrial genome would have favored the evolution of sexual reproduction. Mitochondrial DNA (mtDNA) exhibits a high‐mutation rate across most eukaryote taxa, and several lines of evidence suggest that this high rate is an ancestral character. This seems inexplicable given that mtDNA‐encoded genes underlie the expression of life's most salient functions, including energy conversion. We propose that negative (...) metabolic effects linked to mitochondrial mutation accumulation would have invoked selection for sexual recombination between divergent host nuclear genomes in early eukaryote lineages. This would provide a mechanism by which recombinant host genotypes could be rapidly shuffled and screened for the presence of compensatory modifiers that offset mtDNA‐induced harm. Under this hypothesis, recombination provides the genetic variation necessary for compensatory nuclear coadaptation to keep pace with mitochondrial mutation accumulation. (shrink)

The early literature on base of the pyramid strategies argued that multinational enterprises can contribute significantly to poverty alleviation of the poorest population in the world. An emergent perspective suggests that the solution to poverty lies within the BOP itself. Here, entrepreneurship within the BOP population is seen as the more credible solution to poverty. In this Special Issue introduction, we briefly present how the literature has further shifted the discussion of BOP strategies toward issues such as innovation, networks, business (...) models, and sustainability at the BOP. This analysis signals a gap in our knowledge related to the success factors in business models of BOP entrepreneurs, with attention to economic, social, and environmental impacts. We present the five articles accepted for publication in this Special Issue, of which three contribute to our knowledge of BOP business models and two to our knowledge of sustainability at the BOP. In conclusion, we propose several avenues for future research. (shrink)

Given their salience in many sports and physical cultures, it is surprising that the practices, processes and production of intercorporeality and ‘doing together’ remain under-explored from a sociological perspective. The ongoing achievement of ‘togethering’ can be particularly important for the embodied partnership between a visually impaired (VI) runner and a sighted guide (SG) runner: a specific sporting dyad whose experiences are currently under-researched. To address this lacuna and contribute original insights to sensory sociological studies, here we explore the accomplishment of (...) running-together by VI runners and sighted guides, focusing on the auditory dimension. To illustrate how these runners put the sense of hearing ‘to work’ in achieving finely attuned intercorporeality, often at considerable speed, we draw on qualitative data from a research project on VI running in the UK, involving five VI runners and five SGs. Here, we focus on auditory attunement in two domains identified as highly salient in the running-partners’ intercorporeal experiences: (1) Listening out – auditory attention to non-linguistic sounds; and (2) Tuning in – the importance of attending to team-talk between VI runners and SG runners. (shrink)

Changes in healthcare financing increasingly rely upon patient cost-sharing to control escalating healthcare expenditures. These changes raise new challenges for physicians that are different from those that arose either under managed care or traditional indemnity insurance. Historically, there have been two distinct bases for arguing that physicians should not consider costs in their clinical decisions—an “aspirational ethic” that exhorts physicians to treat all patients the same regardless of their ability to pay, and an “agency ethic” that calls on physicians to (...) be trustworthy advisors to their patients. In the setting of greater patient cost-sharing, physicians' aspiration and agency roles increasingly conflict. Satisfactorily navigating the new terrain of consumer-driven healthcare requires physicians to consider these two roles and how they can best be reconciled so as to maximize quality of care while respecting the heterogeneity of patients' financial resources and willingness to pay. (shrink)

Background Informed consent procedures for large population-based cohort studies should be comprehensive and easy-to-use. This is particularly challenging when participants from different socio-economic groups and multicultural ethnic backgrounds are involved. Recently, more and more studies have tried to use multimedia in informed consent procedures. We describe the development and testing of a digital informed consent app and elaborate on whether this may contribute to a comprehensive and practical procedure to obtain informed consent for public health research. Methods In a sample (...) of parents with young children, we used a mixed method approach to study the user experience of an informed consent app and evaluate whether it can be used to adequately inform people and register their consent. Through semi-structured interviews we investigated participants’ experiences with and opinions about the app, with a special focus on comprehensibility of the content and the usability of the app. Information retention questions were asked to evaluate to what extent participants could recall key aspects of the provided study information. Results The 30 participants in this study used the app between 4 and 15 min to give their consent. Overall, they found the app well-designed, informative and easy to use. To learn more about the study for which informed consent is asked, most of the participants chose to watch the animated film, which was generally found to convey information in a clear manner. The identification process was met with mixed reactions, with some feeling it as a secure way to give consent, while for others it contradicted their view of using data anonymously. Information retention questions showed that while all participants remembered various aspects of the study, fewer than half answered all four questions satisfactorily. Conclusion Our study shows that a well-designed informed consent app can be an effective tool to inform eligible participants and to record consents. Still, some issues remain, including trust barriers towards the identification procedure and lack of information retention in some participants. When implementing consent procedures that incorporate digital formats, it may be beneficial to also invest in a complementary face-to-face recruitment approach. (shrink)

As a conscientious moral agent, a judge in a court of law often finds herself in a difficult position. She is confident that the law requires a certain result in the case before her, but she is at least as confident that this legally required result is unjust or otherwise morally objectionable. Consider some examples of cases in which a reasonable judge might consider herself to be in this position: ▪ The law of landlord and tenant can require a judge (...) to evict an impoverished, elderly widow from her apartment for missing rent payments.1 ▪ A student in a poor school district sues his state for providing a much lower caliber of education than students receive in wealthier districts. Binding legal precedent requires the judge to dismiss the student’s lawsuit. ▪ Binding precedents construing the Fourth Amendment require judges to exclude evidence obtained without a search warrant. As a result, a child molester is acquitted, and, predictably, strikes again. (shrink)

Mutations that disrupt biological rhythms have existed in microbial and metazoan eukaryotes for some time. They have recently begun to be studied with increasing intensity, both in terms of phenotypic effects of the relevant genetic variants, and with regard to molecular isolation and analysis of the genes defined by two of the ‘clock mutations’. These genetic loci, called period (per) in Drosophila and frequency (frq) in Neurospora, influence not only the basic characteristics of circadian rhythmicity, but also temperature compensation of (...) such daily cycle durations, ‘re‐setting’ of the rhythms' phases, and (for the per mutants) behavioral oscillations associated with much shorter than circadian periodicities. Molecular cloning of Drosophila's per gene, accompanied crucially by the locus's identification in germ‐line transformants, has led to information on its expression ‐ temporally, spatially, and in regard to heterogeneity of mRNA types. Nucleotide‐sequencing analyses of genomic DNA (and/or cDNA) from normal and mutated per alleles have (1) led to the suggestion that this clock gene encodes a family of proteoglycans (which was further indicated by application of antibody reagents obtained by manipulation of one of the gene's exons); and (2) shown that the three types of per mutations ‐ which shorten or lengthen rhythm periodicities or appear to eliminate them ‐ are associated with interesting amino‐acid substitutions or a stop codon, respectively. Analogous molecular findings are awaited from Neurospora, whose frq gene has very recently been cloned and definitively identified, in part via transformation experiments. (shrink)

Using Galileo Galilei's Saggiatore and Ludovico Ariosto's Orlando furioso as a focal point, this article evaluates a mixed methods approach for identifying matches of words and phrases that are rich material for close reading and contextualization. The method focuses on ngram matches and networks of phrases that are used together. The similarity of Galileo's treatise to Ariosto's poem is compared to 45 other early modern Italian texts to evaluate the relative exceptionalism or normality of the findings. Ngram matches reveal a (...) series of previously unknown connections between the Saggiatore and Furioso, which indicate an analytical understanding of the poem, rather than borrowing of narrative or figurative expression. Network analysis offers a preliminary outline for two communities of texts that frequently use the same ngrams found in the Furioso. (shrink)

How To Think Philosophically invites reflection on curiosity, wonder, and inquiry. Part I explains philosophy as a way of developing the disciplines and intellectual virtues for seeing and inhabiting the world. Part II introduces the domains of philosophical thinking: epistemology (how we know), metaphysics (what we know), and ethics (how to live).

The ethics of treating the seriously and critically ill have not been static throughout the ages. Twentieth century medicine has inherited from the nineteenth century a science which places an inappropriate weight on diagnosis over prognosis and management, combined with a seventeenth century duty to prolong life. However other earlier ethical traditions, both Hippocratic and Christian, respected both the limitations of medicine and emphasised the importance of prognosis. This paper outlines some of the historical precedents for the treatment of the (...) critically ill, and also how the current paradigm limits clinical practice and causes ethical tensions. An understanding that other paradigms have been ethically acceptable in the past allows wider consideration and acceptance of alternatives for the future. However future alternatives will also have to address the role of technology, given its importance in this area of medicine. (shrink)

In $\textbf{ZF}$, the well-known Fichtenholz–Kantorovich–Hausdorff theorem concerning the existence of independent families of _X_ of size $|{\mathcal {P}} (X)|$ is equivalent to the following portion of the equally well-known Hewitt–Marczewski–Pondiczery theorem concerning the density of product spaces: “The product ${\textbf{2}}^{{\mathcal {P}}(X)}$ has a dense subset of size |_X_|”. However, the latter statement turns out to be strictly weaker than $\textbf{AC}$ while the full Hewitt–Marczewski–Pondiczery theorem is equivalent to $\textbf{AC}$. We study the relative strengths in $\textbf{ZF}$ between the statement “_X_ has (...) no independent family of size $|{\mathcal {P}}(X)|$ ” and some of the definitions of “_X_ is finite” studied in Levy’s classic paper, observing that the former statement implies one such definition, is implied by another, and incomparable with some others. (shrink)

Opponents of the Affordable Care Act have attempted to topple it in court by challenging the legality of two of its three legs. Three years ago, in NFIB v. Sibelius, Chief Justice Roberts narrowly upheld the constitutionality of the individual mandate, in a 5-to-4 decision that characterized the mandate as an optional tax rather than as a regulatory command. This year, on June 25, the health policy community exhaled a giant sigh of relief when the Supreme Court upheld the subsidy (...) leg of the ACA structure. In King v. Burwell, Justice Roberts again wrote the majority opinion, ruling as a matter of statutory interpretation that subsidies for insurance premiums are available not just through state-based exchanges but also through the federal exchange. (shrink)