The focus of this study was to analyze the content, distribution, and comparative genome relationships of 996 chromosome bin-mapped expressed sequence tags accounting for 2266 restriction fragments on the homoeologous group 3 chromosomes of hexaploid wheat. Of these loci, 634, 884, and 748 were mapped on chromosomes 3A, 3B, and 3D, respectively. The individual chromosome bin maps revealed bins with a high density of mapped ESTs in the distal region and bins of low density in the proximal region of the (...) chromosome arms, with the exception of 3DS and 3DL. These distributions were more localized on the higher-resolution group 3 consensus map with intermediate regions of high-mapped-EST density on both chromosome arms. Gene ontology classification of mapped ESTs was not significantly different for homoeologous group 3 chromosomes compared to the other groups. A combined analysis of the individual bin maps using 537 of the mapped ESTs revealed rearrangements between the group 3 chromosomes. Approximately 232 of the consensus mapped ESTs matched sequences on rice chromosome 1 and revealed large- and small-scale differences in gene order. Of the group 3 mapped EST unigenes ∼21 and 32% matched the Arabidopsis coding regions and proteins, respectively, but no chromosome-level gene order conservation was detected. (shrink)

This article is a brief formulation of a radical thesis. We start with the formalist doctrine that mathematical objects have no meanings; we have marks and rules governing how these marks can be combined. That's all. Then I go further by arguing that the signs of a formal system of mathematics should be considered as physical objects, and the formal operations as physical processes. The rules of the formal operations are or can be expressed in terms of the laws of (...) physics governing these processes. In accordance with the physicalist understanding of mind, this is true even if the operations in question are executed in the head. A truth obtained through (mathematical) reasoning is, therefore, an observed outcome of a neuro-physiological (or other physical) experiment. Consequently, deduction is nothing but a particular case of induction. (shrink)