BackgroundPreprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An objective dimension of quality that is readily measurable is completeness of reporting, as transparency can improve the reader’s ability to independently interpret data and reproduce findings.MethodsIn this observational study, we initially compared independent samples of articles published in bioRxiv and in PubMed-indexed journals in 2016 using a quality of reporting questionnaire. After that, we performed paired comparisons (...) between preprints from bioRxiv to their own peer-reviewed versions in journals.ResultsPeer-reviewed articles had, on average, higher quality of reporting than preprints, although the difference was small, with absolute differences of 5.0% [95% CI 1.4, 8.6] and 4.7% [95% CI 2.4, 7.0] of reported items in the independent samples and paired sample comparison, respectively. There were larger differences favoring peer-reviewed articles in subjective ratings of how clearly titles and abstracts presented the main findings and how easy it was to locate relevant reporting information. Changes in reporting from preprints to peer-reviewed versions did not correlate with the impact factor of the publication venue or with the time lag from bioRxiv to journal publication.ConclusionsOur results suggest that, on average, publication in a peer-reviewed journal is associated with improvement in quality of reporting. They also show that quality of reporting in preprints in the life sciences is within a similar range as that of peer-reviewed articles, albeit slightly lower on average, supporting the idea that preprints should be considered valid scientific contributions. (shrink)

This paper investigates the effect of female representation on the board of directors on corporate response to stakeholders’ demands for increased public reporting about climate change-related risks. We rely on the Carbon Disclosure Project as a sustainability initiative supported by institutional investors. Greenhouse gas emissions measurement and its disclosure to investors can be thought of as a first step toward addressing climate change issues and reducing the firm’s carbon footprint. Based on a sample of publicly listed Canadian firms over the (...) period 2008–2014, we find that the likelihood of voluntary climate change disclosure increases with women percentage on boards. We also find evidence that supports critical mass theory with regard to board gender diversity. These findings reinforce initiatives being undertaken around the world to promote gender diversity in corporate governance while demonstrating board effectiveness in stakeholder management. (shrink)

Em vista da grande multiplicidade de linguagens e considerando que a alfabetização é uma importante prática de letramento na constituição da criança, este artigo tem o objetivo de identificar o tipo de abordagem dado à imagem em um livro didático do 1º ano, aprovado pelo PNLD. O intuito é discutir em que medida a amostra analisada favorece uma leitura compreensiva e crítica do texto imagético. Para tanto, as ponderações foram realizadas por meio de uma epistemologia interpretativa, à luz da teoria (...) dos letramentos sob uma perspectiva sociocultural, e também a partir da sintaxe da linguagem visual, que pode trazer uma contribuição positiva às análises discursivas visuais. A pesquisa indica que a imagem é proposta a partir de perspectivas socioculturais; que as atividades de leitura favorecem o letramento visual e que a condução do professor pode fazer diferença nas abordagens e leituras.Considering the multitude of languages and the fact that beginning literacy is a key literacy practice in children's education, we aim at identifying how images are approached in a textbook used in the first grade of elementary school and accredited by Brazil's National Textbook Program. We also seek to discuss the extent to which the analyzed sample provides a comprehensive and critical reading of visual texts. The analysis was done based on interpretive epistemology, the sociocultural approach to literacy, and visual language syntax, which can contribute positively to the analysis of visual discourse. We concluded that the image in the sample is presented from sociocultural approaches, that the reading activities foster visual literacy, and that teachers' support plays a significant role in adopting approaches to reading and in conducting reading activities per se. (shrink)

A teoria literária ofereceu uma contribuição definitiva ao conhecimento histórico, sobretudo se coadunada com uma discussão propriamente epistemológica sobre o seu papel enquanto representação literária. Partindo desta assertiva concordamos que o texto literário cobra um lugar de primeira importância para o conhecimento histórico, pois todo o conhecimento possível do “passado”, enquanto testemunho escrito, nele se constitui enquanto representação e dele emerge para ser de novo reapresentado. Daqui partiremos, ao propor um modus operandi por meio do qual uma fonte literária medieval (...) pode ser apreendida como fonte histórica, ao considerar precisamente conceitos literários, como o individuo e o autor. (shrink)

We review Potts' influential book on the semantics of conventional implicature , offering an explication of his technical apparatus and drawing out the proposal's implications, focusing on the class of CIs he calls supplements. While we applaud many facets of this work, we argue that careful considerations of the pragmatics of CIs will be required in order to yield an empirically and explanatorily adequate account.

Recently, the second author, Briseid, and Safarik introduced nonstandard Dialectica, a functional interpretation capable of eliminating instances of familiar principles of nonstandard arithmetic—including overspill, underspill, and generalizations to higher types—from proofs. We show that the properties of this interpretation are mirrored by first-order logic in a constructive sheaf model of nonstandard arithmetic due to Moerdijk, later developed by Palmgren, and draw some new connections between nonstandard principles and principles that are rejected by strict constructivism. Furthermore, we introduce a variant of (...) the Diller–Nahm interpretation with two different kinds of quantifiers, similar to Hernest’s light Dialectica interpretation, and show that one can obtain nonstandard Dialectica by weakening the computational content of the existential quantifiers—a process called herbrandization. We also define a constructive sheaf model mirroring this new functional interpretation, and show that the process of herbrandization has a clear meaning in terms of these sheaf models. (shrink)

This paper focuses on the interpretation of the Italian approximative adverb quasi 'almost' by primarily looking at cases in which it modifies temporal connectives, a domain which, to our knowledge, has been largely unexplored thus far. Consideration of this domain supports the need for a scalar account of the semantics of quasi (close in spirit to Hitzeman's semantic analysis of almost, in: Canakis et al. (eds) Papers from the 28th regional meeting of the Chicago Linguistic Society, 1992). When paired with (...) suitable analyses of temporal connectives, such an account can provide a simple explanation of the patterns of implication that are observed when quasi modifies locational (e. g. quando 'when'), directional (e. g. fino 'until' and da 'since'), and event-sequencing temporal connectives (e. g. prima 'before' and dopo ' after'). A challenging empirical phenomenon that is observed is a contrast between the modification of fino and da by quasi, on the one hand, and the modification of prima and dopo by the same adverb, on the other. While quasi fino and quasi da behave symmetrically, a puzzling asymmetry is observed between quasi prima and quasi dopo. To explain the asymmetry, we propose an analysis of prima and dopo on which the former has the meaning of the temporal comparative più presto 'earlier', while the latter is seen as an atomic predicate denoting temporal succession between events (Del Prete, Nat Lang Semantics 16: 157-203, 2008). We show that the same pattern of implication observed for quasi prima is attested when quasi modifies overt comparatives, and propose a pragmatic analysis of this pattern that uniformly applies to both cases, thus providing new evidence for the claim that prima is underlyingly a comparative. A major point of this paper is a discussion of the notion of scale which is relevant for the semantics of quasi', in particular, we show that the notion of Horn (entailment-based) scale is not well-suited for handling modification of temporal connectives, and that a more general notion of scale is required in order to provide a uniform analysis of quasi as a cross-categorial modifier. (shrink)

Multidimensional practical demand has made Islamology one of the most "trendy" branches of Oriental studies and has created a host of serious difficulties and problems associated with an adequate scientific response to the "Islamic challenge". Excessive politicization of the study of such a phenomenon as Islamic fundamentalism, radicalism in the world, undoubtedly, undermines the true scientific knowledge, preventing the specialists from understanding this complex phenomenon.

El artículo indaga en la reemergencia de ciertos principios que la Edad Media vinculó al pensamiento de Averroes en pensadores contemporáneos como Giorgio Agamben, Roberto Esposito, Emanuele Coccia y Jean Baptiste Brenet. La eternidad del mundo y la separación del itnelecto vuelven a aparecer como sustento de una filosofía capaz de poner en tela de juicio ideas fundamentales de la modernidad como la de sujeto o persona, sin por ello entramparse en el nihilismo.

Giorgio Agamben’s concepts of ‘the sovereign’, ‘state of exception’ and ‘bare life’ have been used by political theorists, particularly since the declaration of the Global War on Terror and during the more recent age of wars of humanitarian intervention, to conceptualize the sovereignty exercised by security states. These state processes have been mirrored by absolutization within some branches of political theory, conflating Foucauldian concepts of biopolitical sovereignty and circulatory governmentality with notions of absolutist rule, and narrowing optics for interpreting popular (...) mobilizations around gendered ‘human security’ projects, emergency regimes and moralizing repression. Suggesting more productive directions for theory, this article generates a close reading of female activists working in an unexpected industry in Egypt who have struggled to invert and subvert absolutist and moralizing framings and have generated their own theory through practice. The ‘Natashas of Cairo’ – well organized and transnationally linked belly dancers – successfully promoted gendered popular sovereignty in remarkable campaigns between 2002 and 2006, utilizing personal-rights litigation to create frameworks to render the absolutist state more accountable; establish labor solidarities that crossed international boundaries as well as class boundaries; and articulate an alternative moral regime for dance work that rejected both ‘pornification’ and the ‘respectability politics’ of professionalization. (shrink)

ABSTRACT Banks provide a valuable but inherently unstable combination of deposit‐taking and lending functions that were successfully held together for several decades after the New Deal by tough banking rules. The weakening of the rules after the 1970s promoted the displacement of traditional relationship‐based banking with securitized, arms‐length alternatives that encouraged banks to undertake activities about which bankers lacked deep relationship‐based knowledge of the risks. Ironically, this risky behavior, encouraged by loosened regulation, was reinforced by progressively tightened securities regulation, which (...) promoted stock‐market liquidity but also deprived large banks (and other publicly traded companies) of oversight by investors with “insiders’” knowledge. Both the underregulation of banking and the overregulation of securities were underpinned by economic theories that favored blind diversification in liquid, anonymous markets, and that ignored the value of relationship‐based knowledge and case‐by‐case due diligence. (shrink)

New concepts may prove necessary to profit from the avalanche of sequence data on the genome, transcriptome, proteome and interactome and to relate this information to cell physiology. Here, we focus on the concept of large activity-based structures, or hyperstructures, in which a variety of types of molecules are brought together to perform a function. We review the evidence for the existence of hyperstructures responsible for the initiation of DNA replication, the sequestration of newly replicated origins of replication, cell division (...) and for metabolism. The processes responsible for hyperstructure formation include changes in enzyme affinities due to metabolite-induction, lipid-protein affinities, elevated local concentrations of proteins and their binding sites on DNA and RNA, and transertion. Experimental techniques exist that can be used to study hyperstructures and we review some of the ones less familiar to biologists. Finally, we speculate on how a variety of in silico approaches involving cellular automata and multi-agent systems could be combined to develop new concepts in the form of an Integrated cell (I-cell) which would undergo selection for growth and survival in a world of artificial microbiology. (shrink)

This article explores the traditional basis of modern human rights doctrines and exposes some of the systemic shortcomings. It then posits that a number of these problems are advanced via integrating some developments in the philosophy of science and substantive scientific research into legal philosophy. This article argues that supervening holism grounded in quantum mechanics provides an alternative basis to human rights by positing an ontological construct that is congruous with many of the wisdom traditions practiced around the world. Such (...) a foundation exposes a rational imperative for universal human rights and hence appeals to legal pragmatists. (shrink)

Contributed articles with reference to India.

The community representative plays a very important role in an institutional review board but there is sparse data about their understanding of their role in an IRB. This study was conducted to assess perceptions of community members serving on IRBs of one region in India. A validated questionnaire was administered to community members of IRBs in a prospective cross-sectional study. The questions related to demography, perceptions of their role in the IRB, experiences while serving on the IRBs, difficulties faced by (...) them, and suggestions to improve their contributions. Of the 56 IRBs contacted, all 15 of the public institutions shared details of their community members, while only 26 of the 41 IRBs of private institutions responded. When questioned about why they joined the IRB, one third of the respondents said either that there was “no specific reason” for joining or that they accepted the invitation to serve on the insistence of other members of the IRBs or the head of their institution. All except one felt that community members were needed for optimal functioning. Six participants said that they did not review informed consent documents, and 10 were unaware that their presence was vital for quorum to be met. Twenty-eight said they participated actively in meetings and did not feel intimidated by the presence of clinicians. Twelve reported difficulties in understanding medical terminologies in ICDs. Although the majority of participants were aware about their role in an IRB, some did not review important documents such as ICDs. Restricted participation by private hospital IRBs was a striking observation in our study. There is a need to define eligibility criteria and develop targeted training modules for community members to ensure their effective contribution to effective oversight of clinical research. (shrink)

Corporate social responsibility (CSR) aspirations by companies have been identified as a motivating factor for active employee participation in CSR implementation. However, a failure to practise what one preaches can backfire and lead to attribution of hypocrisy. Drawing on a qualitative study of an award-winning sustainability pioneer in the cosmetics sector, we explore the role of moral judgement in how and when employees interpret word–deed misalignment in CSR implementation as hypocritical. First, our case reveals that high CSR aspirations by companies (...) raise employees’ moral expectations. Second, we develop a framework that explains variations in employees’ hypocrisy interpretations based on consequentialist and deontological forms of moral judgement. Our research advances a contextual view of hypocrisy, not as an objective characteristic of an organisation, but as an outcome of interpretative processes of perceived motives and results in CSR implementation. Our framework thereby explains why even highly committed organisations may face accusations of hypocrisy. (shrink)

We propose a semantic analysis of the particles afinal (European Portuguese) and alla fine (Italian) in terms of the notion of truth unpersistence, which combines both epistemic modality and constraints on discourse structure. We argue that the felicitous use of these modal particles requires that the truth of a proposition p* fail to persist through a temporal succession of epistemic states, where p* is incompatible with the proposition modified by afinal/alla fine, and that the interlocutors share knowledge of a previous (...) epistemic attitude toward p*. We analyze two main cases, that of plan-related propositions and that of propositions without plans. We also discuss the connections between truth unpersistence and evidentiality. (shrink)

This paper explores the role of metonymy in determining a syntactic argument alternation (“conductor-vehiclealternation”) which occurs in English and Portuguese:o piloto acelerou a Ferrari“the driver speeded up the Ferrari”/a Ferrari acelerou“the Ferrari speeded up/sped away”. Since the verbs in theconductor-vehiclealternation haveconductorandvehiclearguments (controller and controlled entities), a metonymic process can occur, allowing thevehicleexpression to provide access to theconductorparticipant. To explain how metonymy allows a verb with two participants to be integrated into a construction with a single argument, we assume that metonymy (...) gathers information about both entities involved; thevehicleexpression provides mental access to bothvehicleandconductor(“fusion”). We also discuss cognitive and pragmatic factors involving the choice of a construction over another. Constructions withvehicleexpressions as subject are used when thevehicleis salient or theconductoris unknown. This also explains whydirigir“drive” does not alternate in Portuguese, contrarily to prediction and differently from Englishdrive. We provide a comparative account of the behavior of this verb in both languages.Dirigir, differently fromdrive, conceptualizes semantic components incompatible with a situation in which the agent/conductoris not salient or is unknown. This research adds to the ongoing body of literature on the role of metonymy in grammar and is a contribution to the understanding of the metonymic process, as a fusion, and also to argument alternation processes and lexical-constructional integration. (shrink)

O trabalho pretende, a partir da publicação das “Confissões da Carne”, analisar o impasse que diz respeito a sua não publicação em vida por Foucault, em especial em função da entrada do sujeito como terceiro componente do triângulo arqueológico-genealógico, impondo uma reviravolta decisiva em sua pesquisa. A força aletúrgica do sujeito implica uma definitiva dessoberanização do dispositivo de poder. Por um lado, se a forma moderna prevê a sua transferência de um poder sobre si próprio aos outros, o complexo de (...) estratégias governamentais, que «orientam» a direção da consciência, não implica a abdicação da liberdade por parte da pessoa a qual foi dirigida; por outro, uma segunda operação surge da diferenciação específica entre o modelo antigo e o modelo cristão, quer dizer, se o antigo modelo de direção funciona com vistas à autonomização do sujeito, aquele exame de consciência cristão estabelece como eixo a dependência e desenvolve uma racionalidade pastoral. Assim Foucault chega a uma estética da existência que é puro exercício de liberdade e perfeita atitude, que se oferece aos outros como prova do seu próprio valor. É com isso que o volume quarto da história da sexualidade é confrontado. O que muda drasticamente na experiência cristã da carne é a relação do sujeito com a verdade. A confissão, mais do que expiação dos pecados, neste quadro intervém como atestado e como testemunho de si próprio. Em conclusão, para Foucault, conotado pela imperfeição que o domina, o sujeito cristão liga-se a uma interminável direção de consciência cujo preço é uma perda de identidade indefinida. Assim, a partir deste recorte, o problema que passa a enfrentar é como encontrar uma forma de fundamentar a hermenêutica de si, não no sacrifício, mas numa “emergência positiva”, teórica e prática, de si, expondo tanto o momento transicional das “Confissões da Carne” quanto a própria razão pela qual renuncia à sua publicação. (shrink)

Pour compléter ce numéro et afin de souligner son actualité, nous avons souhaité échanger avec Marianne Amar, historienne, responsable du département de la recherche au Musée National de l’Histoire de l’Immigration (Palais de la Porte-Dorée, Paris). L’entretien s’est tenu le 26 juin 2019 et a duré une heure trente. Comme convenu en juin, Marianne Amar a complété ses propos quelques mois plus tard pour présenter les projets actuels du musée sur le thème « femmes et genre en migration (...) ». Linda... (shrink)

This thesis considers the space of encounter between the quantum mechanical ontology of limited universal holism and the legal system. This space of encounter is identified through an examination of two premises. The first premise is that the ontological structure of limited universal holism has significant legal philosophical and socio-­‐legal implications. The second premise is that the loci of commitment within the ontology of limited universal holism epistemologically coheres with the core ontological notions that underpin the Preamble of the Universal (...) Declaration of Human Rights of 1948,1 specifically the notions of equality, universality and inalienability. Both premises are affirmed in the course of analysis undertaken in this thesis. In addition some novel contributions are posited. Some of the ontological elements of limited universal holism when deployed as heuristic tools show, inter alia, coherence between the way socio-­‐legal constructivists conceptualise the law and the wave-­‐particle duality of quanta. In respect of the second premise, epistemological coherence is shown between the ethos that underpins modern human rights and the loci of commitment within the ontology of limited universal holism. This coherence improves the epistemic stability of monist perspectives on which deep equality may be framed. The thesis concludes with some suggestions for future research. Two particularly exciting areas for future research are uncovered in the course of the analysis. First is the coherence between the work in this thesis and the jurisprudential paradigm of Wild Law. Second is the potential for the monist ontology of limited universal holism derived from scientific research to cohere with many diverse wisdom and ethno-­‐cultural traditions and in so doing increase the epistemic standing of monist ontologies. (shrink)

Situado no campo da discussão entre a filosofia da vida e a fenomenologia, ou mais especificamente entre a escola diltheiana e o círculo fenomenológico, o artigo investiga em que esfera Dilthey é, de fato, relativista, e, no caso afirmativo, até que ponto é possível extrair, de sua posição diante da história, consequências céticas.

This paper provides a semantic analysis of the particles afinal (European Portuguese) and alla fine (Italian) in terms of the notion of truth unpersistence, which can be situated at the intersection of epistemic modality and discourse structure. In the analysis proposed, the particles are propositional operators and require that the truth of a proposition p* fail to persist through a temporal succession of epistemic states, this proposition being incompatible with the prejacent, and that the interlocutors share knowledge of a previous (...) epistemic attitude toward p*. We analyze two main cases (plan-related and non plan-related propositions) and also show that these particles are indexical to one (or more) epistemic agent(s) and allow for shifts in perspective. (shrink)

O conhecimento de si há que se referir, necessariamente, a um si para o conhecimento. Não obstante, em âmbito metafísico e ontológico, o si a ser conhecido deveria ser o mesmo que buscaria conhecer-se. Isto quer dizer que o ser que se deveria conhecer seria anterior ao seu próprio ser enquanto já constituído por este seu conhecimento, ou ainda, seria tal pelo encontro entre o próprio ser em si, bondoso e virtuoso ele mesmo, com aquele que ainda é para ser, (...) e sobre a promoção da sabedoria de si, pela qual essência e existência se encontrariam e se fundiriam na alma. Poderíamos dizer que estamos aqui diante da reelaboração do conhece-te a ti socrático em direção a uma ontologização da alma humana, sobretudo se vista sob a ótica da busca pela autossuficiência do eu espiritual, tão cara ao período helenístico e romano e notadamente a Sêneca. (shrink)

A ética do discurso justifica o conteúdo de uma moralidade que salienta a simetria entre os sujeitos e a solidariedade entre todos. Para Habermas “a solidariedade é a outra face da justiça” (1999, p. 42), ou seja, são duas faces da mesma moeda. Esta é uma afirmação chave em relação ao conteúdo cognitivo do âmbito moral. A validade das normas pressupõe uma fundamentação normativa estruturada linguisticamente, de forma a vincular a justiça com a solidariedade. A ênfase está em uma razão (...) prática capaz de fundamentar princípios igualitários e universalistas da moral e do direito (2009, p. 63). A legitimação do estado de direito deve preservar sua neutralidade ideológica, alicerçada em uma moral racional, isto é, laica (ou secular). Com isso, as exigências normativas devem ser aceitas por todos em uma sociedade pluralista, formada por cidadãos de diferentes credos e, inclusive, por não crentes (HABERMAS, 2009, p. 69). (shrink)