Objective: Atypical patterns of language lateralization due to early reorganizational processes constitute a challenge in the pre-surgical evaluation of patients with pharmaco-resistant epilepsy. There is no consensus on an optimal analysis method used for the identification of language dominance in MEG. This study examines the concordance between MEG source localization of beta power desynchronization and fMRI with regard to lateralization and localization of expressive and receptive language areas using a visual verb generation task.Methods: Twenty-five patients with pharmaco-resistant epilepsy, including six (...) patients with atypical language lateralization, and ten right-handed controls obtained MEG and fMRI language assessment. Fourteen patients additionally underwent the Wada test. We analyzed MEG beta power desynchronization in sensor (controls) and source space (patients and controls). Beta power decrease between 13 and 35 Hz was localized applying Dynamic Imaging of Coherent Sources Beamformer technique. Statistical inferences were grounded on cluster-based permutation testing for single subjects.Results: Event-related desynchronization of beta power in MEG was seen within the language-dominant frontal and temporal lobe and within the premotor cortex. Our analysis pipeline consistently yielded left language dominance with high laterality indices in controls. Language lateralization in MEG and Wada test agreed in all 14 patients for inferior frontal, temporal and pari... (shrink)

Abraham ibn Ezra d'Espagne (m. 1167) fut l'un des plus importants savants ayant contribué à la transmission de la science arabe à l'Occident. Ses ouvrages en astrologie et en astronomie, rédigés en hébreu puis traduits en latin, étaient considéréd comme faisant autorité par de nombreux savants juifs et Chrétiens. Parmi les ouvrages qu'il a traduits de l'arabe en hébreu, certains sont perdus dans leur langue originale et ses propres ouvrages renferment certaines informations concernant des sources anciennes mal ou pas (...) du tout connues par ailleurs. Ibn Ezra semble être le premier a avoir consigne l'une des sept méthodes pour dresser les maisons astrologiques. Cette méthode avait par la suite été utilisée par Lévi ben Gershom (m. 1344) dans le Midi de la France. (shrink)

In astronomy Abraham Zacut is best known for the Latin version of his tables, the Almanach Perpetuum, first published in 1496, based on the original Hebrew version that he composed in 1478. These tables for Salamanca, Spain, were analyzed by the authors of this paper in 2000. We now present Zacut’s tables preserved in Latin and Hebrew manuscripts that have not been studied previously, with a concordance of his tables in different sources. Based on a hitherto unnoticed text in (...) a Latin manuscript, we argue that Zacut is the author of the Tabule verificate which, in our publication of 2000, we took to be anonymous. We also discuss in detail Zacut’s tables for epoch 1513 for Jerusalem that are arranged for the Hebrew calendar, rather than the Julian calendar that he used elsewhere. We then consider a number of fragmentary texts that were found in the Cairo Geniza, now scattered in various European and American libraries. The new evidence is consistent with our earlier finding that Zacut depended both on the medieval Hebrew tradition in astronomy and on the Parisian Alfonsine Tables. (shrink)

In this paper, we analyze the astronomical tables for 1340 by Immanuel ben Jacob Bonfils who flourished 1340–1365, based on four Hebrew manuscripts. We discuss the relation of these tables principally with those of al-Battānī, Abraham Bar Ḥiyya, and Levi ben Gerson, as well as with Bonfils’s better known tables, called Six Wings. An unusual feature of this set of tables is that there are two kinds of mean motion tables, one arranged for Julian years from 1340 to 1380, (...) months, days, hours, and minutes of an hour, and the other arranged in the Hebrew calendar for the times of conjunctions and oppositions of the Sun and the Moon only, with subtables for 19-year cycles, single years in a 19-year cycle, and months. The latter arrangement is found in Bonfils’s Six Wings for solar and lunar motions only, whereas in his Tables for 1340, this arrangement applies to all planets. Notably absent are tables for the trigonometric functions, etc., that are generally found in such sets of astronomical tables. (shrink)

Les idéaux et pratiques d’amélioration personnelle visant à atteindre un sens de réalisation de soi ont imprégné la culture populaire depuis le milieu du xxe siècle, en grande partie grâce au travail des psychologues humanistes américains. Cet article explore la popularisation de ces notions, arguant qu’elles découlent en partie d’une appropriation américaine particulière du concept d’« actualisation de soi» du neurologue et psychiatre allemand Kurt Goldstein. Premièrement, l’article examine la rencontre de Goldstein avec la psychologie américaine, retraçant son (...) intérêt précoce pour la psychothérapie, les étapes de sa migration forcée vers l’Amérique, et la réception de son travail au sein de la psychologie américaine. Deuxièmement, il propose une analyse des interprétations et applications de l’approche holistique de Goldstein et de son concept d’auto-réalisation par les praticiens humanistes, notamment la théorie de la motivation d’Abraham Maslow et l’approche centrée sur le client de Carl Rogers en psychothérapie. Enfin, l’article se termine par une discussion critique de la distinction entre l’approche de Goldstein, qui met l’accent sur le processus créatif d’un « débat» entre l’organisme et le milieu, et la psychothérapie humaniste, qui souligne la responsabilité individuelle. (shrink)

One important thesis Ásta defends in Categories We Live By is that social properties and categories are somehow dependent on our thoughts, attitudes, or practices—that they are inventions of the mind, projected onto the world. Another important aspect of her view is that the social properties are related to certain base properties; an individual is placed in a category when the relevant base properties are thought to hold of them. I see the relationship between the social and the base as (...) connected to the problem of explaining how the social properties are sufficiently stable so as to be taken seriously, both in theoretical endeavors as well as in practical matters of how we relate to each other. In this light, I identify stability constraints for an adequate account of social categories. I argue that certain distinctive aspects of Ásta's conferralist view of social categories, such as the radical contextualism in her account of gender, undermine the stability of categories and are at odds with taking social categories seriously. I end with the suggestion that a distinctive “sheltered” form of normativity might help us do justice to Ásta's insights while avoiding some of the destabilizing elements of conferralism. (shrink)

What is it for a duty or obligation to be directed? Thinking about paradigmatic cases such as the obligations generated by promises will take us only so far in answering this question. This paper starts by surveying several approaches for understanding directed duties, as well as the challenges they face. It turns out that shared agency features something similar to the directedness of duties. This suggests an account of directedness in terms of shared agency – specifically, in terms of the (...) so-called practical intimacy that holds between individuals when they act together. The final section addresses a challenge to the shared agency approach posed by legal wronging in tort law. (shrink)

While cochlear implantation is now considered routine in many parts of the world, the debate over how to ethically implement this technology continues. One’s stance on implantation often hinges on one’s understanding of deafness. On one end of the spectrum are those who see cochlear implants as a much needed cure for an otherwise intractable disability. On the other end of the spectrum are those who view the Deaf as members of a thriving culture and see the cochlear implant as (...) an attempt to eliminate this culture. Rather than take a stance in this debate, we will argue that the informed consent process for cochlear implantation must include access to Deaf perspectives. Deaf individuals know best what it is like to be a member of the Deaf community; the reasonable person would put significant weight on the testimony of Deaf individuals when considering whether to undergo cochlear implantation. The reasonable person standard determines what information careproviders must present as part of the informed consent process; thus, informed consent for cochlear implantation requires access to the testimony of Deaf individuals. (shrink)

Immediately before the release of DSM-5, a group of psychiatric thought leaders published the results of field tests of DSM-5 diagnostic criteria. They characterized the interrater reliability for diagnosing major depressive disorder by two trained mental health practitioners as of “questionable agreement.” These field tests confirmed an open secret among psychiatrists that our current diagnostic criteria for diagnosing major depressive disorder are unreliable and neglect essential experiences of persons in depressive episodes. Alternative diagnostic criteria exist, but psychiatrists rarely encounter them, (...) forestalling the discipline’s epistemological crisis. In Alsadair MacIntyre’s classic essay, such crises occur in science when a person encounters a rival schemata that is incompatible with their current schemata and subsequently constructs a narrative that allows them to reconstruct their own tradition. In search of rival schemata that are in conversation with their own tradition, psychiatric practitioners can utilize alternative diagnostic criteria like the Cultural Formulation Interview, embrace an epistemologically humble psychiatry, and attend to the narrative experience of a person experiencing a depressive episode. (shrink)

While copious quantities of ink have been spilled on the topic of autonomy in the context of health care, little has been written about autonomy in relation to intellectual disability. After presenting the received account of capacity, we argue that it cannot account for the moral permissibility of limiting an individual with intellectual disability’s access to diet soda. In cases of preventative medicine and intellectual disability, the philosophical motivation for the received account of capacity is incompatible with the actions it (...) recommends. We consider and reject several potential solutions; then, drawing on applied behavior analysis and the phenomenon of automatic reinforcement, we propose our own solution. The article concludes by considering the broader implications of our discussion. (shrink)

This book examines reason and unreason in the legal and political responses to terrorism. Terrorism is often perceived as sheer madness, unreasonable use of extreme violence and senseless, futile political action. These assertions are challenged by this book. Combining ‘traditional’ thought on reason and unreason in terrorism with empirical explorations of post-modern terrorism and its use of communication platforms the work uses interdisciplinary and cross disciplinary dimensions to provide a multidimensional picture of critical issues in current politics and a deeper (...) examination of their implications than previously available. The book looks at various aspects of modern politics, from terrorism to protest, from decision-making to political discourse, applying the perspective of philosophical thought. To do so, political issues and actions are examined by using concepts such as reason, emotions, madness, magic, morality, absolutism, extremism, psychopathology, rationality and others. The analysis is rooted in theories and concepts derived from history, philosophy, religion, art, sociology, psychology, and political science. This book, which was mostly written by the late Abraham Kaplan, an American philosopher, and edited and updated by Gabriel Weimann, will be of much interest to students of political violence/terrorism, philosophy, war and conflict studies and political science in general. (shrink)

The book that the French reader holds in his hands is one of the century’s most fascinating and liberating. It does nothing less than instigate the psychoanalytic approach as a universal method of...

What are the implications for agency – and in particular, the idea of acting for reasons – if we are to take seriously the notion of collective responsibility? My thesis is that some cases of individuals subject to a collective form of responsibility and blame will force us to make sense of how it is that an individual can be entitled to collective reasons for action, i.e. entitled to a reason had in the first place by a plurality of individuals (...) together rather than any one of them alone. This entitlement makes it possible for the collective reason to be a reason for which one acts, even if one’s contribution on its own makes little or no difference in the collective effort. Although a full defense of this entitlement cannot be undertaken here, I will gesture at how this might work by suggesting that intentions function to preserve reasons for action. . (shrink)

We present some techniques in c.c.c. forcing, and apply them to prove consistency results concerning the isomorphism and embeddability relations on the family of ℵ 1 -dense sets of real numbers. In this direction we continue the work of Baumgartner [2] who proved the axiom BA stating that every two ℵ 1 -dense subsets of R are isomorphic, is consistent. We e.g. prove Con). Let K H, be the set of order types of ℵ 1 -dense homogeneous subsets of R (...) with the relation of embeddability. We prove that for every finite model L, : Con iff L is a distributive lattice. We prove that it is consistent that the Magidor-Malitz language is not countably compact. We deal with the consistency of certain topological partition theorems. E.g. We prove that MA is consistent with the axiom OCA which says: “If X is a second countable space of power ℵ 1, and { U 0,\h.;, U n−1 } is a cover of D ▪ X x X -} x,x> ¦ x ϵ X } consisting of symmetric open sets, then X can be partitioned into { X i \brvbar; i ϵ ω } such that for every i ϵ ω there is l such that D ⊇ U l ”. We also prove that MA+OCA [xrArr] 2 ℵ 0 = ℵ 2. (shrink)

The distinction often made between “ethics of virtue” and “ethics of duty” may have led to the suggestion that the Aristotelian and Kantian conceptions of morality were fundamentally different from each other. This distinction could justify refusing to consider the motives of virtuous action as “moral” motivations in the strict sense. Yet, is it not the same thing to act in a virtuous manner as to act “by seeing”? Rosalind Hursthouse can thus note, as early as the end of the (...) last century, that there is “growing enthusiasm” for the idea that “the ideal Kantian agent” and “the ideal neo-Aristotelian agent” are “not so different from what they were supposed to be”. We would like to examine this thesis by going back to its sources in some temporal interpretations of the Kantian conception of action accomplished “by duty”. (shrink)

Scaling of pattern with size has been described and studied for over a century, yet its molecular basis is understood in only a few cases. In a recent, elegant study, Inomata and colleagues proposed a new model explaining how bone morphogenic protein (BMP) activity gradient scales with embryo size in the early Xenopus laevis embryo. We discuss their results in conjunction with an alternative model we proposed previously. The expansion‐repression mechanism (ExR) provides a conceptual framework unifying both mechanisms. Results of (...) Inomata and colleagues implicate the chordin‐stabilizing protein sizzled as the expander molecule enabling scaling, while we attributed this role to the BMP ligand Admp. The two expanders may work in concert, as suggested by the mathematical model of Inomata et al. We discuss approaches for differentiating the contribution of sizzled and Admp to pattern scaling. (shrink)

In Bohmian mechanics the distribution |ψ|2 is regarded as the equilibrium distribution. We consider its uniqueness, finding that it is the unique equivariant distribution that is also a local functional of the wave function ψ.

Most medical consultations are for self‐limiting conditions. While technical expertise remains necessary, creating therapeutic knowledge in this context is the joint responsibility of physician and patient, and depends upon recognition that the observer, the observation, and the observed form a temporary union.

This article explores Hegel’s Philosophy of Right as a work on education that responds to two democratic ideals: the ideal of individual integrity, which demands that individuals come to know the principles that animate them of their own accord, and the ideal of collectivism, which demands that individuals be at home in a shared world. While the great political works of Plato and Rousseau fasten on one of these ideals at the expense of the other, I show that Hegel’s political (...) philosophy accepts both. The result is what I call the paradox of democratic education. Hegel solves this paradox through a three-fold pedagogical strategy which speaks to the transformational possibilities of institutions as well as more directly to the needs of the “ironic consciousness.” This strategy reveals a Hegel who calls on us to strengthen our commitment to a democratic polity through a deeper conception of the requirements of democratic education. (shrink)

If nowadays categories seems to cover a multitude of different enquiries, we can see some continuity and coherence among them, and we can get some sense of what the subject is, by going back to the first treatise to receive the name, the Categories of Aristotle. The scheme of categories worked out by Aristotle in that book was used by him in subsequent works to solve a variety of problems. On one plausible hypothesis, Aristotle’s scheme was partly shaped by ontological (...) considerations. However, one can construct categorial schemes that are free of ontological assumptions, and I call such schemes and the principles on which they are constructed “pure.” A purified Aristotelian scheme is one of a multiplicity of categorial schemes that can be generated by a sufficiently general pure categorial principle. In the penultimate section of this paper I consider a useful scheme, generated in this way, that categorizes the elements of our discourse about discourse. This links up with J. L. Austin’s discussion of the nature of illocutionary acts and throws light on the interconnections between such problematic notions as sentence, meaning, and proposition. (shrink)