Mireille Hadas-Lebel shines a spotlight on the complex life and works of Philo, the illustrious Alexandrian Jewish philosopher, offering a fascinating insight into a seminal religious thinker at the crossroads of Judaism and Hellenism.

This article presents the results of an evaluative research on the impacts of collaborative research in the evolution of the practices of researchers and associated teachers. It was a question of understanding how the collaborative approach was useful and relevant to the participants, how it enabled them to better take ownership of their role as an associate teacher, and how to transform their practices.

On propose ici trois avenues de recherche susceptibles d’élucider le lien un peu mystérieux entre dialectique et mathématiques dans la philosophie d’Albert Lautman.This note proposes three lines of work that might help to shed some light on the problematic nexus between dialectical ideas and mathematical theories in Albert Lautman’s thinking.

BackgroundFear of cancer recurrence is common amongst cancer survivors. There is rapidly growing research interest in FCR but a need to prioritize research to address the most pressing clinical issues and reduce duplication and fragmentation of effort. This study aimed to establish international consensus among clinical and academic FCR experts regarding priorities for FCR research.MethodsMembers of the International Psycho-oncology Society Fear of Cancer Recurrence Special Interest Group were invited to participate in an online Delphi study. Research domains identified in Round (...) 1 were presented and discussed at a focus group to consolidate the domains and items prior to presentation in further survey rounds aimed at gaining consensus on research priorities of international significance.ResultsThirty four research items were identified in Round 1 and 33 of the items were consolidated into six overarching themes through a focus group discussion with FCR experts. The 33 research items were presented in subsequent rounds of the delphi technique. Twenty one participants contributed to delphi round 1, 16 in round 2, and 25 and 29 participants for subsequent delphi rounds. Consensus was reached for 27 items in round 3.1. A further four research items were identified by panelists and included in round 3.2. After round 3.2, 35 individual research items were ratified by the panelists. Given the high levels of consensus and stability between rounds, no further rounds were conducted. Overall intervention research was considered the most important focus for FCR research. Panelists identified models of care that facilitate greater access to FCR treatment and evaluation of the effectiveness of FCR interventions in real world settings as the two research items of highest priority. Defining the mechanisms of action and active components across FCR/P interventions was the third highest priority identified.ConclusionThe findings of this study outline a research agenda for international FCR research. Intervention research to identify models of care that increase access to treatment are based on a flexible approach based on symptom severity and can be delivered within routine clinical care were identified as research areas to prioritize. Greater understanding of the active components and mechanisms of action of existing FCR interventions will facilitate increased tailoring of interventions to meet patient need. (shrink)

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

While cancer survivors commonly experience fear and anxiety, a substantial minority experience an enduring and debilitating fear that their cancer will return; a condition commonly referred to as fear of cancer recurrence. Despite recent advances in this area, little is known about FCR among people from Indigenous or other ethnic and racial minority populations. Given the high prevalence and poor outcomes of cancer among people from these populations, a robust understanding of FCR among people from these groups is critical. The (...) current review identified and aggregated existing literature on FCR amongst adult cancer survivors from Indigenous and minority populations. The protocol of this review was registered with PROSPERO in July 2020. A systematic search of bibliographic databases was conducted for relevant articles published from 1997 to November 2019. Data from eligible articles were extracted and appraised for quality by two independent reviewers. Nineteen articles from four countries met the inclusion criteria, including 14 quantitative, 4 qualitative and 1 mixed-methods study. Only one article reported on an Indigenous population. Few studies reported on FCR prevalence or severity. While the variation in tools used to measure FCR hindered a robust estimate of severity, results suggested some differences in FCR severity between minority and dominant populations, although these may have been due to study metholodological differences. Few factors were reported as being associated with FCR in minorities across multiple studies. The qualitative synthesis found five themes associated with the lived experience of FCR: variations in the lived experience of FCR; spirituality and worldview impacting on FCR; the importance of staying positive; complexities around support; and increasing cancer knowledge. The findings of this review highlight differences in FCR across cultures and contexts, which reinforces the need for culturally-specific approaches to this condition. The dearth of research in this area is of concern given the significant burden of cancer in these populations. A deeper understanding of this condition among Indigenous and minority populations is critical to developing and delivering appropriate and effective psychosocial care for cancer survivors from these groups. Systematic Review Registration: identifier [CRD42020161655]. (shrink)

The book under review discusses the most standard forms of mathematical realism, a.k.a. ‘Platonism’, elaborated in the mainstream of twentieth-century philosophy of mathematics. Its purpose is therefore to introduce franco phone readers to an important set of ideas that have been, for the most part, cultivated by analytic philosophers. It originates from a doctoral dissertation at Université Paris 1. It comprises 287 pages of text divided into four main parts, completed by an eight-page bibliography. Beginning with Frege, Russell, and Gödel, (...) Xavier Sabatier discusses the work of several contemporary Platonists, such as Quine, Resnik, Shapiro, and Maddy. Since the last no longer considers herself a Platonist in mathematics , the author restricts his commentary to her Realism in Mathematics .The introductory first part ends with a discussion of the standard objections to realism. The fourth part of the book, which is also its conclusion, revisits those objections and shows how, in the light of what has been said, they can be overcome to some extent from within a naturalist stance. Following the first part, one finds two long sections entitled ‘A priori realism’ and ‘Naturalized realism’. The first focuses on the Frege-Russell brand of logical Platonism, prefigured in the work of Bolzano, and on Gödel’s version of realism. The second examines the renewal of realism emanating from Quine’s project of a naturalized epistemology. It is in this section that Sabatier considers some contemporary authors like Penelope Maddy, Michael Resnik, and Stewart Shapiro. Some might find it questionable to associate the structuralism of Resnik and Shapiro with Platonism, given the naturalistic stance of those philosophers but it is nevertheless an excellent idea to discuss their work in such a context. Indeed, one can give interpretations of Plato’s Sophist and of other late dialogues that …. (shrink)

In this theoretical contribution, we interpret the notion of professional development in the light of concepts coming from cognitive development. This brings us to consider teacher training as not only having to allow the elaboration of skills, but also as having to encourage the development of new cognitive structures. We explore the theoretical concepts in relation with certain processes revealed by the reflexive texts of the students. Finally, we propose ways that could foster certain dimensions of global professional development in (...) learners, among which self-regulated learning, the focus on certain concerns and taking into account certain types of information. (shrink)

Pre-reading language skills develop rapidly in early childhood and are related to brain structure and functional architecture in young children prior to formal education. However, the early neurobiological development that supports these skills is not well understood. Here we acquired anatomical, diffusion tensor imaging and resting state functional MRI from 35 children at 3.5 years of age. Children were assessed for pre-reading abilities using the NEPSY-II subtests 1 year later. We applied a data-driven linked independent component analysis to explore the (...) shared co-variation of gray and white matter measures. Two sources of structural variation at 3.5 years of age demonstrated relationships with Speeded Naming scores at 4.5 years of age. The first imaging component involved volumetric variability in reading-related cortical regions alongside microstructural features of the superior longitudinal fasciculus. The second component was dominated by cortical volumetric variations within the cerebellum and visual association area. In a subset of children with rs-fMRI data, we evaluated the inter-network functional connectivity of the left-lateralized fronto-parietal language network and its relationship with pre-reading measures. Higher functional connectivity between the FPL and the default mode and visual networks at 3.5 years significantly predicted better Phonological Processing scores at 4.5 years. Together, these results suggest that the integration of functional networks, as well as the co-development of white and gray matter brain structures in early childhood, support the emergence of pre-reading measures in preschool children. (shrink)

In 2021, the Bigelow Institute for Consciousness Studies (hereafter, BICS) sponsored an essay competition (hereafter, the Contest) designed to solicit the best evidence for the hypothesis that human consciousness survives bodily death, and more specifically, evidence that would prove this hypothesis beyond a reasonable doubt. The summer 2022 issue of the Journal of Scientific Exploration featured a special subsection on the BICS contest and its winning essays. Robert Bigelow and Colm Kelleher outlined the motivation, design, and judging criteria for the (...) competition. Keith Augustine provided an extensive critical commentary on the contest design and eight of its prominent winning essays. Stephen Braude and several coauthors responded to Augustine’s criticisms, and Augustine provided a reply to Braude and his collaborators. Finally, the subsection concluded with a collaborative paper in which Etienne LeBel, Adam Rock, and Augustine proposed a more rigorous experimental design for testing the survival hypothesis. Augustine presented important criticisms of the Contest and several of its prominent winning essays. Moreover, many of his criticisms apply to survival literature in general and so are instructive for the wider survival debate. And Braude, one of the most important contributors to the survival debate since C.D. Broad and C.J. Ducasse, was at the helm of the reply to Augustine. Although the response to Augustine raised important concerns about skeptical assessments of the evidence for survival, it was hamstrung with several defects. 1. Preliminaries 2. Problematic Aspects of the Reply to Augustine 3. What is the Question? Honing in on the Actual Disagreement 4. Inference to Best Explanation 5. Confirmation Approaches to Evidential Support -- 5.1 Evidential Justification -- 5.2 When Does an Observation Favor One Hypothesis Over Another Hypothesis? The Law of Likelihood -- 5.3 When Should We Up Our Confidence in a Hypothesis? Incremental Confirmation -- 5.4 How Can We Determine the Net Plausibility of a Hypothesis? Bayes’ Theorem and Posterior Probabilities -- 5.5 Which of Two Hypotheses is More Probable than the Other? Principle of Contrastive Posterior Probabilities -- 5.6 When Does Evidence Justify Believing a Hypothesis? Principle of Absolute Confirmation -- 5.7 Survivalist Confusions about Bayesian Analyses -- 5.8 The Washing Out of Priors -- 5.9 The Subjectivism Objection -- 5.10 Summing Up Insights from Confirmation Theory -- 6. Back to Braude 7. Varieties of Skepticism 8. Neurophysiological Evidence and the Survival Hypothesis 9. The Data from Mediumship 10. The Alleged Improbability of Fraud and Other Counterexplanations 11. Mediumship and the Logic of Confirmation 12. The Significance of Failed Tests 13. Survivalist Rescues and Contrastive Confirmation 14. Evidential Support without Predictions -- 15. The Testability Problem -- Concluding Remarks. (shrink)