Results for 'non-homologous end-joining'

952 found
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  1.  33
    Can Designer Indels Be Tailored by Gene Editing?Sara G. Trimidal, Ronald Benjamin, Ji Eun Bae, Mira V. Han, Elizabeth Kong, Aaron Singer, Tyler S. Williams, Bing Yang & Martin R. Schiller - 2019 - Bioessays 41 (12):1900126.
    Genome editing with engineered nucleases (GEENs) introduce site‐specific DNA double‐strand breaks (DSBs) and repairs DSBs via nonhomologous end‐joining (NHEJ) pathways that eventually create indels (insertions/deletions) in a genome. Whether the features of indels resulting from gene editing could be customized is asked. A review of the literature reveals how gene editing technologies via NHEJ pathways impact gene editing. The survey consolidates a body of literature that suggests that the type (insertion, deletion, and complex) and the approximate length of indel (...)
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  2.  35
    Radiation‐induced chromosome aberrations: Insights gained from biophysical modeling.Lynn Hlatky, Rainer K. Sachs, Mariel Vazquez & Michael N. Cornforth - 2002 - Bioessays 24 (8):714-723.
    Enzymatic misrepair of ionizing‐radiation‐induced DNA damage can produce large‐scale rearrangements of the genome, such as translocations and dicentrics. These and other chromosome exchange aberrations can cause major phenotypic alterations, including cell death, mutation and neoplasia. Exchange formation requires that two (or more) genomic loci come together spatially. Consequently, the surprisingly rich aberration spectra uncovered by recently developed techniques, when combined with biophysically based computer modeling, help characterize large‐scale chromatin architecture in the interphase nucleus. Most results are consistent with a picture (...)
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  3.  17
    Hypothesis: transcript‐templated repair of DNA double‐strand breaks.Deborah A. Trott & Andrew C. G. Porter - 2006 - Bioessays 28 (1):78-83.
    Two mechanisms are available for the repair of DNA double‐strand breaks (DSBs) in eukaryotic cells: homology directed repair (HDR) and non‐homologous end‐joining (NHEJ). While NHEJ is not restricted to a particular phase of the cell cycle, it is incapable of accurately repairing DBSs that have suffered a loss or gain of nucleotide sequence information. In contrast, HDR achieves accurate repair of such DSBs by use of a sister chromatid as a DNA template, but is restricted to cell cycle (...)
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  4.  33
    BioEssays 12/2019.Sara G. Trimidal, Ronald Benjamin, Ji Eun Bae, Mira V. Han, Elizabeth Kong, Aaron Singer, Tyler S. Williams, Bing Yang & Martin R. Schiller - 2019 - Bioessays 41 (12):1970125.
    Graphical AbstractGene editing with engineered nucleases introduce double-strand breaks that are repaired by error-prone nonhomologous end-joining (NHEJ). In article number 1900126, Sara G. Trimidal et al. propose that the length and type or resulting indels can now be controlled by editing with different engineered nucleases or by manipulating the expression of NHEJ genes.
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  5.  18
    Chromosomal breaks at the origin of small tandem DNA duplications.Joost Schimmel, Marloes D. van Wezel, Robin van Schendel & Marcel Tijsterman - 2023 - Bioessays 45 (1):2200168.
    Small tandem DNA duplications in the range of 15 to 300 base‐pairs play an important role in the aetiology of human disease and contribute to genome diversity. Here, we discuss different proposed mechanisms for their occurrence and argue that this type of structural variation mainly results from mutagenic repair of chromosomal breaks. This hypothesis is supported by both bioinformatical analysis of insertions occurring in the genome of different species and disease alleles, as well as by CRISPR/Cas9‐based experimental data from different (...)
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  6.  23
    Replication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrity.Sarah K. Deng, Huan Chen & Lorraine S. Symington - 2015 - Bioessays 37 (3):305-313.
    Replication protein A (RPA) is the main eukaryotic single‐stranded DNA (ssDNA) binding protein, having essential roles in all DNA metabolic reactions involving ssDNA. RPA binds ssDNA with high affinity, thereby preventing the formation of secondary structures and protecting ssDNA from the action of nucleases, and directly interacts with other DNA processing proteins. Here, we discuss recent results supporting the idea that one function of RPA is to prevent annealing between short repeats that can lead to chromosome rearrangements by microhomology‐mediated end (...)
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  7.  22
    Non-philosophical mystique and the rehabilitation of heresis.Eleni Lorandou - 2018 - Labyrinth: An International Journal for Philosophy, Value Theory and Sociocultural Hermeneutics 20 (1):51-63.
    In the second part of the Triptych, Mystique non-philosophique à l'usage des contemporains, François Laruelle puts to the test of "non-philosophy" the field of phenomena that are termed as "religious" whether Christian, Judaic or Gnostic. Non-philosophical mystique is born in the spirit of heresy rather than sanctity. It springs from the effort to join Man with himself rather than with God founding the radical cause of the new Logos in the One-in-One. Man is emptied from his identity, becomes a Christ-subject (...)
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  8.  46
    Faith among Faiths: Christian Theology and Non-Christian Religions (review).Catherine Cornille - 2001 - Buddhist-Christian Studies 21 (1):130-132.
    In lieu of an abstract, here is a brief excerpt of the content:Buddhist-Christian Studies 21.1 (2001) 130-132 [Access article in PDF] Book Review Faith Among Faiths: Christian Theology and Non-Christian Religions Faith Among Faiths: Christian Theology and Non-Christian Religions. By James L. Fredericks. Mahwah, New Jersey: Paulist Press, 1999. 188 pp. "The time has come to recognize that the debate between exclusivists, inclusivists, and pluralists has reached an impasse."This is the starting point and refrain of Faith Among Faiths. While James (...)
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  9.  15
    Non-anthropocentric creative mechanisms in multispecies symbiotic assemblages.Nevena Ivanova - 2016 - Technoetic Arts 14 (3):225-233.
    So well established was the cliché which connected TB and creativity that at the end of the century one critic suggested that it was the progressive disappearance of TB which accounted for the current decline of literature and the arts'. Some biochemical evidence does indeed invite a hypothesis that M. tuberculosis originally joined the human holobiont as a brain evolution-enhancing endosymbiont, thus possibly contributing towards the development of human consciousness and creative potential. Exploring the complexity of mycobacteria's entanglements within human (...)
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  10.  47
    The Case for Ethical Non-compete Agreements: Executives Versus Sandwich-Makers.Lauren E. Aydinliyim - 2020 - Journal of Business Ethics 175 (3):651-668.
    Human capital, the knowledge, skills, and abilities of employees, can be a powerful driver of firm performance, yet the mobility of human capital raises questions over how to protect it. Employee non-compete agreements, which limit an employee’s ability to start or join a rival firm, have received recent attention. While past research considers whether non-competes are effective tools at limiting employee mobility, few have considered if non-competes should be used. Filling this gap, I propose a normative schema for when employee (...)
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  11.  17
    Tracking Object-State Representations During Real-Time Language Comprehension by Native and Non-native Speakers of English.Xin Kang & Haoyan Ge - 2022 - Frontiers in Psychology 13.
    The present “visual world” eye-tracking study examined the time-course of how native and non-native speakers keep track of implied object-state representations during real-time language processing. Fifty-two native speakers of English and 46 non-native speakers with advanced English proficiency joined this study. They heard short stories describing a target object either having undergone a substantial change-of-state or a minimal change-of-state while their eye movements toward competing object-states and two unrelated distractors were tracked. We found that both groups successfully directed their visual (...)
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  12.  26
    Introduction: Quis se Caesaribus notus non fingit amicum?Richard Talbert - 2011 - American Journal of Philology 132 (1):1-13.
    In lieu of an abstract, here is a brief excerpt of the content:Introduction:Quis se Caesaribus notus non fingit amicum? 1Richard TalbertThis volume owes its origin to a chance encounter in March 2008. As fellow Roman historians, David Potter and I always welcome the opportunity of a conversation whenever our paths happen to cross. Finding myself in Ann Arbor in this instance, I mentioned to David as we talked how impressed I was with the recently published volume The Court and Court (...)
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  13.  23
    Active genetics comes alive.Valentino M. Gantz & Ethan Bier - 2022 - Bioessays 44 (8):2100279.
    Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)‐based “active genetic” elements developed in 2015 bypassed the fundamental rules of traditional genetics. Inherited in a super‐Mendelian fashion, such selfish genetic entities offered a variety of potential applications including: gene‐drives to disseminate gene cassettes carrying desired traits throughout insect populations to control disease vectors or pest species, allelic drives biasing inheritance of preferred allelic variants, neutralizing genetic elements to delete and replace or to halt the spread of gene‐drives, split‐drives with the core constituent (...)
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  14.  19
    Bilateral Interference in Motor Performance in Homologous vs. Non-homologous Proximal and Distal Effectors.Morten Andreas Aune, Håvard Lorås, Alexander Nynes & Tore Kristian Aune - 2021 - Frontiers in Psychology 12.
    Performance of bimanual motor actions requires coordinated and integrated bilateral communication, but in some bimanual tasks, neural interactions and crosstalk might cause bilateral interference. The level of interference probably depends on the proportions of bilateral interneurons connecting homologous areas of the motor cortex in the two hemispheres. The neuromuscular system for proximal muscles has a higher number of bilateral interneurons connecting homologous areas of the motor cortex compared to distal muscles. Based on the differences in neurophysiological organization for (...)
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  15.  59
    Intimate distance: Rethinking the unthought God in christianity.Laurens ten Kate - 2008 - Sophia 47 (3):327-343.
    The work of the French philosopher Jean-Luc Nancy shares with the thinkers of the ‘theological turn in phenomenology’ the programmatic desire to place the ‘theological’, in the broad sense of rethinking the religious traditions in our secular time, back on the agenda of critical thought. Like those advocating a theological turn in phenomenology, Nancy’s deconstructive approach to philosophical analysis aims to develop a new sensibility for the other, for transcendence, conceptualized as the non-apparent in the realm of appearing phenomena. This (...)
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  16.  43
    For the Synthesis was a Boojum, you see. [REVIEW]Ehud Lamm - 2018 - Notre Dame Philosophical Reviews 1:0-0.
    This collection joins a long parade of attempts to slay an aging, decrepit, beast. This beast of mythical status being the Modern Synthesis in evolutionary biology. As some of the authors in this collection note, it is far from clear whether these attempts do not in fact invigorate the beast, keeping it alert and nimble. As someone in the business of developing traps for the monster and its lookalikes, reading this collection I found myself identifying with the beast, clearly the (...)
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  17.  40
    Living Dangerously with Bruno Latour in a Hybrid World.Mark Elam - 1999 - Theory, Culture and Society 16 (4):1-24.
    This article critically engages with the work of Bruno Latour and, in particular, his book We Have Never Been Modern. Looking beyond the wit and brevity of Latour's writing, the article focuses on some of the non-innocent aspects of his vision of a non-modern world. Rather than completely rejecting the `Great Divides' between Nature and Culture, Westerners and non-Westerners, Latour is seen as only interested in erasing these major fault lines of modernity in order to draw them anew. Ultimately, Latour (...)
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  18.  17
    The Mind‐Body Union.Chantal Jaquet - 2021 - In Yitzhak Y. Melamed (ed.), A Companion to Spinoza. Hoboken, NJ: Wiley. pp. 296–303.
    Spinoza breaks with Descartes’ conception of the psychophysical union and deeply changes the ontological statute of men. He considers no longer that human beings in Nature are a dominion within a dominion and share with God the privilege of being substances. In Descartes, the union of an immaterial or non‐extended substance and a material or extended substance remains beyond understanding, since the problem of whether they are able to interact arises. By identifying the mind to the idea of the body, (...)
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  19.  4
    University EFL Students’ Perspectives on Educators’ Digital Competence at Qassim University.Nawrs Sarhan Mardan, Dr Atard Awad Al-Sharifi & Dr Abdul Ali Kazim Al-Maamouri - forthcoming - Evolutionary Studies in Imaginative Culture:2015-2027.
    Personal and professional success in the digital age requires digital abilities. Increased expectations that graduates be adept in digitisation while joining the job need higher education institutions to successfully incorporate digital aspects. This study evaluates university EFL students' digital integrative attitudes and instructors' digital proficiency. Digital tools are emphasised for collaborative learning. Researchers seek to address two key questions: What are EFL students’ perspectives on digital learning? How do they assess teachers' IT skills? It appears through the end result (...)
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  20.  2
    Factors Influencing the Foreign Policy of Azerbaijan in the Context of Globalization.Ilaha Alizade & Elshad Mirbashir Oghlu - 2024 - Metafizika 7 (3):229-240.
    At the end of the 20th century, global processes led to a fundamental shift in the international political environment. In addition to the emergence of new independent states within the international system, various international actors, such as transnational financial organizations and non-governmental organizations-which have gained significant importance due to globalization-contributed to the transformation of the international relations system. These changes were reflected in the foreign policies of many states. Azerbaijan, which gained independence in 1991, redefined its foreign policy to protect (...)
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  21.  7
    The Epistemology of Protest by José Medina (review).Shannon Brick - 2024 - Kennedy Institute of Ethics Journal 34 (1):1-12.
    In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Epistemology of Protest by José MedinaShannon Brick (bio)Review of José Medina, The Epistemology of Protest ( Oxford University Press, 2023)José Medina's previous book, The Epistemology of Resistance (2012), examined epistemic practices as forms of political resistance. His latest book, The Epistemology of Protest, takes up an obviously political action and examines it as a distinctly epistemic phenomenon. He argues that from an epistemic perspective, protest does much (...)
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  22.  18
    A Bad Dream or Cruel Reality? Some Thoughts on the Origin, Developments and Aftermath of the Warsaw Uprising of 1944.Wieńczysław J. Wagner - 2004 - Dialogue and Universalism 14 (5-6):153-166.
    The traditional German policy was to “push to the East”. After signing a non-aggression pact with the Soviet Union, Germany invaded Poland on September 1, 1939, and the Red Army entered the Polish territory on September 17.The German occupation was marked by terror and executions. A resistance movement was developed, and along a secret government and underground army came into being. It was organized by officers who were not taken prisoners of war and by main political parties. The German retaliation—arrests, (...)
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  23.  22
    Social and Moral Aspects of the War.Bertrand Russell & Andrew G. Bone - 2022 - Russell: The Journal of Bertrand Russell Studies 42 (1):52-62.
    In lieu of an abstract, here is a brief excerpt of the content:Social and Moral Aspects of the WarBertrand Russell and Introduced by Andrew G. BoneAmong nine loose-leaf folders of typed transcriptions of Russell's History of Western Philosophy lectures at the Barnes Foundation1 are two copies of a fourteen-page stenographic record of a political talk he gave there on 2 March 1941.2 The bulk of this significant new accrual to the Russell Archives, bearing as it does on Russell's most successful (...)
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  24.  4
    Skulls, the “Mazze,” and the Promise of Union: Political Symbolism and Culture of Peasant Protest in the Milk Delivery Strikes of Western Switzerland, 1945– 1951.Juri Auderset - 2024 - Substance 53 (3):88-109.
    This contribution investigates a specific agricultural protest movement that emerged towards the end of the Second World War in Western Switzerland. In the spring of 1945, dissatisfied farmers in the French-speaking part of Switzerland founded the “Union Romande des Agriculteurs” (URA), a peasant opposition movement that struggled against both the increasing power of the state and the existing farmers’ organizations in regulating agriculture and the disintegrating impact of industrial capitalism on the livelihoods and way of life of farming communities. In (...)
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  25.  4
    The Living from the Dead: Disaffirming Biopolitics.Michelle Ballif - 2024 - Philosophy and Rhetoric 57 (3):347-355.
    In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Living from the Dead: Disaffirming Biopolitics by Stuart J. MurrayMichelle BallifThe Living from the Dead: Disaffirming Biopolitics, by Stuart J. Murray. University Park: Pennsylvania State University Press, The RSA Series in Transdisciplinary Rhetorics, 2022. 207 pp. ISBN 9780271093413 (hardback) $109.95 ISBN 9780271093406 (paper) $27.50If we but listen, we can hear a voice from the grave—Jacques Derrida's mournful lamentation: "There is no longer, there has never been a (...)
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  26.  18
    Philosophical empiricism from the scientific standpoint.James K. Feibleman - 1962 - Dialectica 16 (1):5-14.
    RésuméPour les Grecs en général et pour Platon en particulier, il y avait trois sujets principaux d'intérět: la nature, Dieu et l'homme. Pour Platon, Dieu était l'intermédiaire entre le monde naturel des apparences et celui des ětres; et pour Aristote, Dieu se trouvait aux deux extrémités d'un monde naturel unique en devenir. Le Moyen Age s'est occupé uniquement de Dieu et de l'homme. Les œuvres scientifiques grecques émigrèrent vers l'est dans la période hellénistique où elles furent reprises par les Arabes (...)
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  27.  26
    On Partnership.Ryan Schwarz, Duncan Smith-Rohrberg Maru, Dan Schwarz, Bibhav Acharya, Bijay Acharya, Ruma Rajbhandari, Jason Andrews, Gregory Karelas, Ranju Sharma & Mark Arnoldy - 2012 - Narrative Inquiry in Bioethics 2 (2):101-106.
    In lieu of an abstract, here is a brief excerpt of the content:On PartnershipRyan Schwarz, Duncan Smith-Rohrberg Maru, Dan Schwarz, Bibhav Acharya, Bijay Acharya, Ruma Rajbhandari, Jason Andrews, Gregory Karelas, Ranju Sharma, and Mark ArnoldyRecently, Bayalpata Hospital, in the rural district of Achham, Nepal almost collapsed under the weight of its own staff's discontent. The hospital had been largely abandoned until 2009 when our organization, Nyaya Health, renovated and opened it in partnership with the Nepali government. Since then, the hospital (...)
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  28.  24
    Ad Unguem.Armand J. D'Angour - 1999 - American Journal of Philology 120 (3):411-427.
    In lieu of an abstract, here is a brief excerpt of the content:Ad UnguemArmand J. D'Angour vos, oPompilius sanguis, carmen reprehendite, quod nonmulta dies et multa litura coercuit atquepraesectum deciens non castigavit ad unguem.(Horace Ars Poetica 291–94) You, OSons of Pompilius, condemn that poem whichmany a day and many an erasure has not pruned andwhittled down and chastened tenfold to the nail."Censure a poem," Brink paraphrases, "which has not been reduced to right proportions and (when it has been reduced) has (...)
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  29.  15
    Christology and Ethics.Lindsey Esbensen - 2010 - Journal of the Society of Christian Ethics 32 (1):211-212.
    In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Christology and EthicsLindsey EsbensenChristology and Ethics Edited by F. Leron Shults and Brent Waters Grand Rapids, Mich.: Eerdmans, 2010. 231 pp. $28.00.This collection of essays is a welcome venture into the often-neglected relationship between Christology and ethics. The book stresses that the reciprocal relationship between Christology and Christian moral discernment needs greater attention as well as creative reformulation. The essays produce a variety of models of how other (...)
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  30.  47
    Bataille and Mysticism: A "Dazzling Dissolution".Amy M. Hollywood - 1996 - Diacritics 26 (2):74-85.
    In lieu of an abstract, here is a brief excerpt of the content:Bataille and Mysticism: A “Dazzling Dissolution”Amy Hollywood (bio)Within Georges Bataille’s texts of the late 1930s and 1940s, in particular those later brought together in the tripartite Atheological Summa, he repeatedly suggests that his primary models for writing and experience are the texts of the Christian and non-Western mystical traditions (often represented, in Bataille, by women’s writings) and those of Friedrich Nietzsche. 1 Inner Experience opens with evocations of Nietzsche, (...)
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  31.  35
    Table of Contents [print edition].Andrew G. Bone & Gülberk Koç Maclean - 2022 - Russell: The Journal of Bertrand Russell Studies 42 (1):52-62.
    In lieu of an abstract, here is a brief excerpt of the content:Social and Moral Aspects of the WarBertrand Russell and Introduced by Andrew G. BoneAmong nine loose-leaf folders of typed transcriptions of Russell's History of Western Philosophy lectures at the Barnes Foundation1 are two copies of a fourteen-page stenographic record of a political talk he gave there on 2 March 1941.2 The bulk of this significant new accrual to the Russell Archives, bearing as it does on Russell's most successful (...)
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  32.  21
    Nonviolence—A Brief History: The Warsaw Lectures by John Howard Yoder.Carter Aikin - 2013 - Journal of the Society of Christian Ethics 33 (1):216-217.
    In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Nonviolence—A Brief History: The Warsaw Lectures by John Howard YoderCarter AikinNonviolence—A Brief History: The Warsaw Lectures John Howard Yoder Edited By Paul Martens, Matthew Porter, and Myles Werntz Waco, Tex.: Baylor University Press, 2010. 150 pp. $29.95This helpful collection of lectures, delivered during a 1983 Polish Ecumenical Council (PEC) conference in Warsaw, displays John Howard Yoder’s emerging conviction that nonviolent action is not only a faithful response but (...)
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  33.  25
    …duplici modo Daemon homini carnaliter copulatur : Ludovico Maria Sinistrari's Alternative to Apostasy and Sorcery in Human- Incubus Intercourse.Bert Roest - 2022 - Franciscan Studies 80 (1):191-209.
    In lieu of an abstract, here is a brief excerpt of the content:…duplici modo Daemon homini carnaliter copulatur:Ludovico Maria Sinistrari's Alternative to Apostasy and Sorcery in Human-Incubus IntercourseBert RoestLodovico Maria Sinistrari d'Ameno (1632-1701), who joined the Riformati branch in 1647 in the Pavian Provincia di S. Diego, is one of the many productive seventeenth-century Franciscan authors whose works are not habitually discussed within the world of Franciscan scholarship. According to the existing bibliographical guides, Sinistrari authored under his own name and (...)
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  34. Error Theory in Metaethics.Jonas Olson - 2017 - In Tristram Colin McPherson & David Plunkett (eds.), The Routledge Handbook of Metaethics. New York: Routledge. pp. 58-71.
    Error theories have been proposed and defended in several different areas of philosophy. In addition to ethics, there are error theories about numbers, color, free will, and personal identity. Moral error theories differ in scope. Theories at one end of the spectrum take normative judgments in general—of which moral judgments are a subclass—to be uniformly false, whereas theories at the other end of the spectrum take only a subclass of moral judgments—example those concerning duty and obligation, but not those concerning (...)
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  35. Must There Be Basic Action?Douglas Lavin - 2012 - Noûs 47 (2):273-301.
    The idea of basic action is a fixed point in the contemporary investigation of the nature of action. And while there are arguments aimed at putting the idea in place, it is meant to be closer to a gift of common sense than to a hard-won achievement of philosophical reflection. It first appears at the stage of innocuous description and before the announcement of philosophical positions. And yet, as any decent magician knows, the real work so often gets done in (...)
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  36.  18
    Intimate Distance: Rethinking the Unthought God in Christianity.Laurens Kate - 2008 - Sophia 47 (3):327-343.
    The work of the French philosopher Jean-Luc Nancy shares with the thinkers of the ‘theological turn in phenomenology’ the programmatic desire to place the ‘theological’, in the broad sense of rethinking the religious traditions in our secular time, back on the agenda of critical thought. Like those advocating a theological turn in phenomenology, Nancy’s deconstructive approach to philosophical analysis aims to develop a new sensibility for the other, for transcendence, conceptualized as the non-apparent in the realm of appearing phenomena. This (...)
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  37.  36
    Causes of War.Bertrand Russell - 2023 - Russell: The Journal of Bertrand Russell Studies 43 (1):83-84.
    In lieu of an abstract, here is a brief excerpt of the content:Causes of WarBertrand RussellRussell’s authorship of this anonymously published entry in An Encylopaedia of Pacifism (London: Chatto & Windus, 1937), pp. 12–13, has only just come to light, thanks to the recent sale at auction of a letter to him from Aldous Huxley. If this determination had been made earlier, the text would have featured in Papers 21. In acknowledging receipt of “Causes of War” on 14 December 1936, (...)
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  38.  37
    Transgressive Translations: Parrhesia and the Politics of Being Understood.Tim R. Johnston - 2013 - philoSOPHIA: A Journal of Continental Feminism 3 (1):84-97.
    In lieu of an abstract, here is a brief excerpt of the content:Transgressive Translations:Parrhesia and the Politics of Being UnderstoodTim R. JohnstonAuthor And Activist Julia Serano’s spoken word poem “Performance Piece” is a smart and passionate polemic against people who say that “all gender is performance” (Serano 2010, 85). In response to those who treat gender as an endlessly mutable fiction, performance, or facade Serano says:Sure, I can perform gender: I can curtsy, or throw like a girl, or bat my (...)
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  39. The Method of In-between in the Grotesque and the Works of Leif Lage.Henrik Lübker - 2012 - Continent 2 (3):170-181.
    “Artworks are not being but a process of becoming” —Theodor W. Adorno, Aesthetic Theory In the everyday use of the concept, saying that something is grotesque rarely implies anything other than saying that something is a bit outside of the normal structure of language or meaning – that something is a peculiarity. But in its historical use the concept has often had more far reaching connotations. In different phases of history the grotesque has manifested its forms as a means of (...)
     
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  40.  17
    Human Perfection in Byzantine Theology: Attaining the Fullness of Christ by Alexis Torrance (review).Joshua H. Lim - 2023 - Nova et Vetera 21 (1):373-381.
    In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Human Perfection in Byzantine Theology: Attaining the Fullness of Christ by Alexis TorranceJoshua H. LimHuman Perfection in Byzantine Theology: Attaining the Fullness of Christ by Alexis Torrance, Changing Paradigms in Historical and Systematic Theology (Oxford: Oxford University Press, 2020), ix + 239 pp.As a part of the series Changing Paradigms in Historical and Systematic Theology, Alexis Torrance's Human Perfection in Byzantine Theology examines the role of Christ's human (...)
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  41.  97
    ?Save the music??: Toward culturally relevant, joyful, and sustainable school music.Julia Koza - 2006 - Philosophy of Music Education Review 14 (1):23-38.
    In lieu of an abstract, here is a brief excerpt of the content:“Save The Music”?Toward Culturally Relevant, Joyful, and Sustainable School MusicJulia Eklund KozaIf historical sources are reliable indicators, music educators have never felt confident that music's place in the U.S. public school curriculum is secure. Proponents have been developing exhaustive rationales for the existence of school music from the moment that the subject was introduced into the public schools, attempting to convince an apparently skeptical public of the merits of (...)
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  42.  26
    Affective Spaces: Architecture and the Living Body by Federico de Matteis.Jasna Sersic - 2022 - Environment, Space, Place 14 (2):142-144.
    In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Affective Spaces: Architecture and the Living Body by Federico de MatteisJasna SersicAffective Spaces: Architecture and the Living Body BY FEDERICO DE MATTEIS New York, NY: Routledge, 2021What is architectural space? For architects, urban planners, and all involved in the design and transformation of the environment, space is a central subject. However, despite this fact, nobody accurately states what space is all about. As a result, the concept of (...)
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  43.  19
    The Challenge of Political Right.R. D. Winfield - 2012 - Hegel Bulletin 33 (1):57-70.
    For politics to measure up to reason, two requirements have long been acknowledged: first, that the ends of political action be universal, and second, that the pursuit of such universal ends consist in political self-determination, that is, in self-government.Aristotle set the stage for all further political inquiry by distinguishing political association through the universality of its end or good, while identifying the end of politics with political activity itself, an activity in which citizens rule over one another while presiding over (...)
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  44.  43
    Against the Ethicists (Adversus Mathematicos XI), and: Contro gli etici (review).John Christian Laursen - 1998 - Journal of the History of Philosophy 36 (2):313-315.
    In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Against the Ethicists (Adversus Mathematicos XI) by Sextus EmpiricusJohn Christian LaursenSextus Empiricus. Against the Ethicists (Adversus Mathematicos XI). Translation, Commentary, and Introduction by Richard Bett. Oxford: Clarendon Press, 1997. Pp. xxxiv + 302. NP.Sesto Empirico. Contro gli etici. Introduction, Editing, Translation, and Commentary by Emidio Spinelli. Naples: Bibliopolis, 1995. Pp. 450. NP.Joining the rising tide of scholarly literature that says that skeptics can indeed live their skepticism, (...)
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  45.  33
    Citizen Science on Your Smartphone: An ELSI Research Agenda: Currents in Contemporary Bioethics.Mark A. Rothstein, John T. Wilbanks & Kyle B. Brothers - 2015 - Journal of Law, Medicine and Ethics 43 (4):897-903.
    Beginning in the 20th century, scientific research came to be dominated by a growing class of credentialed, professional scientists who overwhelmingly displaced the learned amateurs of an earlier time. By the end of the century, however, the exclusive realm of professional scientists conducting research was joined, to a degree, by “citizen scientists.” The term originally encompassed non-professionals assisting professional scientists by contributing observations and measurements to ongoing research enterprises. These collaborations were especially common in the environmental sciences, where citizen scientists (...)
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  46. Introduction: Women in Public Life in Republican Rome.Harriet I. Flower & Josiah Osgood - 2024 - American Journal of Philology 145 (1):1-9.
    In lieu of an abstract, here is a brief excerpt of the content:Introduction:Women in Public Life in Republican RomeHarriet I. Flower and Josiah OsgoodThe five articles in this special issue of AJP seek to advance our understanding of republican Rome by paying close attention to women in relation to space. Using a range of sources and approaches, contributors find women throughout the city of Rome—on the streets, in the Forum, in houses (some of which were owned by women), and at (...)
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  47.  32
    Internal bolshevisation? Elite social science training in stalinist Poland.John Connelly - 1996 - Minerva 34 (4):323-346.
    From the viewpoint of its Stalinist-era creators, the IKKN/INS could at best be described as a mixed success. Despite heroic efforts, it failed to train the cadres that might have permeated Polish scholarship with Marxism-Leninism. If it was the major channel for transmitting Soviet experience to Polish academia, then Poland's universities would not learn to be Soviet—the Polish historian Jerzy Halbersztadt has made the point that the institute was the only direct conduit of Soviet experience into Polish academic life. It (...)
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  48.  25
    Inhibitory non-invasive brain stimulation to homologous language regions as an adjunct to speech and language therapy in post-stroke aphasia: a meta-analysis.Begonya Otal, Manuel C. Olma, Agnes Flöel & Ian Wellwood - 2015 - Frontiers in Human Neuroscience 9.
  49.  46
    The Rhetoric of RHETORIC: The Quest for Effective Communication (review).Carolyn R. Miller - 2006 - Philosophy and Rhetoric 39 (3):261-263.
    In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Rhetoric of RHETORIC: The Quest for Effective CommunicationCarolyn R. MillerThe Rhetoric of RHETORIC: The Quest for Effective Communication. Wayne C. BoothMalden, Mass: Blackwell, 2004. Pp. xvi + 206. $20.95, paperback.By using the traditional word rhetoric I want to suggest a whole philosophy of how men succeed or fail in discovering together, in discourse, new levels of truth (or at least agreement) that neither side suspected before.—Wayne C. (...)
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  50.  22
    L'austerité de la vie morale. [REVIEW]S. D. - 1957 - Review of Metaphysics 10 (3):540-540.
    A scholarly and imaginative contribution to ethics and aesthetics. The author sees in certain types of abstract art an affectation of austerity which he interprets as compensation in the aesthetic realm for moral lassitude, and a symptom of the decadence which characterizes our age. Decadence is natural and inevitable; in fact, everything is decadence, but in some ages, notably ours, decadence becomes monstrous. The author distinguishes two types of austerity: the limited and rational, and the infinite. Rational austerity is the (...)
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