Results for 'coagulation testing'

970 found
Order:
  1.  17
    Clustering of Thrombin Generation Test Data Using a Reduced Mathematical Model of Blood Coagulation.N. Ratto, A. Tokarev, P. Chelle, B. Tardy-Poncet & V. Volpert - 2019 - Acta Biotheoretica 68 (1):21-43.
    Correct interpretation of the data from integral laboratory tests, including Thrombin Generation Test, requires biochemistry-based mathematical models of blood coagulation. The purpose of this study is to describe the experimental TGT data from healthy donors and hemophilia A and B patients. We derive a simplified ODE model and apply it to analyze the TGT data from healthy donors and HA/HB patients with in vitro added tissue factor pathway inhibitor antibody. This model allows the characterization of hemophilia patients in the (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  2.  35
    Prevalence and type of pre‐analytical problems for inpatients samples in coagulation laboratory.Gian L. Salvagno, Giuseppe Lippi, Antonella Bassi, Giovanni Poli & Gian C. Guidi - 2008 - Journal of Evaluation in Clinical Practice 14 (2):351-353.
  3.  28
    Experimentation and theory choice: is thrombin an enzyme?James A. Marcum - 1996 - Perspectives on Science 4 (4):434-462.
    Approaches to the analysis of theory choice in science studies often focus either on objective criteria or subjective values for evaluating theories or on critical experiments for testing theories. In the present article a historical case study in the biomedical sciences is reconstructed, in which experimentation was performed to choose between two competing theories of blood coagulation. Analysis of this case study reveals that experimentation exhibits a particular structure, composed of design, execution, and results, and specific characteristics, consisting (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  4.  20
    Contrasting Medical and Legal Standards of Evidence: A Precision Medicine Case Study.Gary E. Marchant, Kathryn Scheckel & Doug Campos-Outcalt - 2016 - Journal of Law, Medicine and Ethics 44 (1):194-204.
    As the health care system transitions to a precision medicine approach that tailors clinical care to the genetic profile of the individual patient, there is a potential tension between the clinical uptake of new technologies by providers and the legal system's expectation of the standard of care in applying such technologies. We examine this tension by comparing the type of evidence that physicians and courts are likely to rely on in determining a duty to recommend pharmacogenetic testing of patients (...)
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  5. Magnet Wires Involved in Test Program As mentioned above, this paper will compare properties of six magnet wire types (imide-modified as well as con-ventional types) relative to use in hermetic motors; factors such as flexibility, abrasion resistance, heat shock, will not. In.A. Extractibles Test - 1968 - In Peter Koestenbaum, Proceedings. [San Jose? Calif.,: [San Jose? Calif.. pp. 127.
    No categories
     
    Export citation  
     
    Bookmark  
  6.  7
    Simone de Beauvoir: Le Refus de l'avenir. L'image de la femme dans Les Mandarins et Les Belles Images.Mary Lawrence Test - 1994 - Simone de Beauvoir Studies 11 (1):19-29.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  7.  8
    Hazel Rowley’s Tête-à-Tête: Simone de Beauvoir and Jean-Paul Sartre.Mary Lawrence Test & Myrna Bell Rochester - 2006 - Simone de Beauvoir Studies 22 (1):92-94.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  8.  14
    Tony Judt’s Intellectuals and the Very Last of the Enlightenment.Mary Lawrence Test - 1993 - Simone de Beauvoir Studies 10 (1):285-288.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  9.  12
    From Moscow to Chicago and Back: Simone de Beauvoir, Political Peripatetic.Mary Lawrence Test & Myrna Bell Rochester - 1995 - Simone de Beauvoir Studies 12 (1):59-72.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  10.  9
    The Ephemera.Turing Test - 2004 - In Stuart M. Shieber, The Turing Test: Verbal Behavior as the Hallmark of Intelligence. MIT Press. pp. 97.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark  
  11.  9
    Esthetics in Action: The Operative Limits of Committed Fiction.Myrna Bell Rochester & Mary Lawrence Test - 1993 - Simone de Beauvoir Studies 10 (1):91-114.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  12. Joseph R. Des jardins and Ronald Duska.Drug Testing in Employment 100 - 2003 - In William H. Shaw, Ethics at work: basic readings in business ethics. New York: Oxford University Press.
     
    Export citation  
     
    Bookmark  
  13.  14
    Simone de Beauvoir: Living Through Conflict.Myrna Bell Rochester & Mary Lawrence Test - 1992 - Simone de Beauvoir Studies 9 (1):17-30.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  14. Critical period, 241-242.Implications Test - 1997 - In M. McCallum & W. Piper, Psychological Mindedness: A Contemporary Understanding. Lawrence Erlbaum. pp. 59--271.
  15.  11
    The Politics of Violence and the Violence of Politics in the Works of Simone de Beauvoir.Myrna Bell Rochester & Mary Lawrence Test - 1996 - Simone de Beauvoir Studies 13 (1):184-201.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  16.  9
    In Memoriam: Dominque Desanti (1919-2011), “Forty plus years of friendship, thanks to Simone de Beauvoir”.Myrna Bell Rochester & Mary Lawrence Test - 2011 - Simone de Beauvoir Studies 27 (1):93-96.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  17.  7
    Why and How We Should Read Beauvoir Today and What We Can Learn from Our Reading.Myrna Bell Rochester & Mary Lawrence Test - 2007 - Simone de Beauvoir Studies 23 (1):91-95.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  18.  27
    A painful message: Testing the effects of suffering and understanding on punishment judgments.Eyal Aharoni, David Simpson, Eddy Nahmias & Mario Gollwitzer - 2022 - Zeitschrift Für Psychologie 230 (2):138-151.
    This preregistered experiment examined two proximate drivers of retributive punishment attitudes: the motivation to make the perpetrator suffer, and understand the wrongfulness of his offense. In a sample of 514 US adults, we presented criminal case summaries that varied the level of suffering (absent vs. present) and understanding (absent vs. present) experienced by the perpetrator and measured punishment judgments and attitudes. Our results demonstrate, as predicted, that participants were more satisfied by the sentence and less punitive when they believed that (...)
    Direct download  
     
    Export citation  
     
    Bookmark   2 citations  
  19. Entrapment, temptation and virtue testing.Daniel J. Hill, Stephen K. McLeod & Attila Tanyi - 2022 - Philosophical Studies 179 (8):2429–2447.
    We address the ethics of scenarios in which one party entraps, intentionally tempts or intentionally tests the virtue of another. We classify, in a new manner, three distinct types of acts that are of concern, namely acts of entrapment, of intentional temptation and of virtue testing. Our classification is, for each kind of scenario, of itself neutral concerning the question whether the agent acts permissibly. We explain why acts of entrapment are more ethically objectionable than like acts of intentional (...)
    Direct download (6 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  20.  80
    Non-Invasive Prenatal Testing for “Non-Medical” Traits: Ensuring Consistency in Ethical Decision-Making.Hilary Bowman-Smart, Christopher Gyngell, Cara Mand, David J. Amor, Martin B. Delatycki & Julian Savulescu - 2021 - American Journal of Bioethics 23 (3):3-20.
    The scope of noninvasive prenatal testing (NIPT) could expand in the future to include detailed analysis of the fetal genome. This will allow for the testing for virtually any trait with a genetic contribution, including “non-medical” traits. Here we discuss the potential use of NIPT for these traits. We outline a scenario which highlights possible inconsistencies with ethical decision-making. We then discuss the case against permitting these uses. The objections include practical problems; increasing inequities; increasing the burden of (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   18 citations  
  21.  69
    Theory testing in science—the case of solar neutrinos: Do crucial experiments test theories or theorists?Trevor Pinch - 1985 - Philosophy of the Social Sciences 15 (2):167-187.
  22.  58
    Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?Michelle J. Bayefsky & Benjamin E. Berkman - 2022 - American Journal of Bioethics 22 (2):4-22.
    Prenatal genetic testing is becoming available for an increasingly broad set of diseases, and it is only a matter of time before parents can choose to test for hundreds, if not thousands, of genetic conditions in their fetuses. Should access to certain kinds of fetal genetic information be limited, and if so, on what basis? We evaluate a range of considerations including reproductive autonomy, parental rights, disability rights, and the rights and interests of the fetus as a potential future (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   17 citations  
  23. Theory-testing in psychology and physics: A methodological paradox.Paul E. Meehl - 1967 - Philosophy of Science 34 (2):103-115.
    Because physical theories typically predict numerical values, an improvement in experimental precision reduces the tolerance range and hence increases corroborability. In most psychological research, improved power of a statistical design leads to a prior probability approaching 1/2 of finding a significant difference in the theoretically predicted direction. Hence the corroboration yielded by "success" is very weak, and becomes weaker with increased precision. "Statistical significance" plays a logical role in psychology precisely the reverse of its role in physics. This problem is (...)
    Direct download (8 more)  
     
    Export citation  
     
    Bookmark   61 citations  
  24. On Testing for Conversational Implicature.Jerrold M. Sadock - 1978 - In Peter Cole, Syntax and Semantics: Pragmatics. Academic Press. pp. 281–297.
     
    Export citation  
     
    Bookmark   73 citations  
  25.  7
    In Memoriam: Béatrix Beck.Susan Petit, Myrna Bell Rochester & Mary Lawrence Test - 2009 - Simone de Beauvoir Studies 25 (1):102-106.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  26.  34
    Empowerment through health self-testing apps? Revisiting empowerment as a process.Alexandra Kapeller & Iris Loosman - 2023 - Medicine, Health Care and Philosophy 26 (1):143-152.
    Empowerment, an already central concept in public health, has gained additional relevance through the expansion of mobile health (mHealth). Especially direct-to-consumer self-testing app companies mobilise the term to advertise their products, which allow users to self-test for various medical conditions independent of healthcare professionals. This article first demonstrates the absence of empowerment conceptualisations in the context of self-testing apps by engaging with empowerment literature. It then contrasts the service these apps provide with two widely cited empowerment definitions by (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   7 citations  
  27.  84
    The Ethics of Online Controlled Experiments (A/B Testing).Andrea Polonioli, Riccardo Ghioni, Ciro Greco, Prathm Juneja, Jacopo Tagliabue, David Watson & Luciano Floridi - 2023 - Minds and Machines 33 (4):667-693.
    Online controlled experiments, also known as A/B tests, have become ubiquitous. While many practical challenges in running experiments at scale have been thoroughly discussed, the ethical dimension of A/B testing has been neglected. This article fills this gap in the literature by introducing a new, soft ethics and governance framework that explicitly recognizes how the rise of an experimentation culture in industry settings brings not only unprecedented opportunities to businesses but also significant responsibilities. More precisely, the article (a) introduces (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   4 citations  
  28. Hypothesis testing: The role of confirmation.R. D. Tweney, M. E. Doherty & C. R. Mynatt - 1981 - In Ryan D. Tweney, Michael E. Doherty & Clifford R. Mynatt, On scientific thinking. New York: Columbia University Press. pp. 115--128.
     
    Export citation  
     
    Bookmark   59 citations  
  29. Access to Prenatal Testing and Ethically Informed Counselling in Germany, Poland and Russia.Marcin Orzechowski, Cristian Timmermann, Katarzyna Woniak, Oxana Kosenko, Galina Lvovna Mikirtichan, Alexandr Zinovievich Lichtshangof & Florian Steger - 2021 - Journal of Personalized Medicine 11 (9):937.
    The development of new methods in the field of prenatal testing leads to an expansion of information that needs to be provided to expectant mothers. The aim of this research is to explore opinions and attitudes of gynecologists in Germany, Poland and Russia towards access to prenatal testing and diagnostics in these countries. Semi-structured interviews were conducted with n = 18 gynecologists in Germany, Poland and Russia. The interviews were analyzed using the methods of content analysis and thematic (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  30.  18
    Regulatory safeguards needed if preimplantation genetic testing for polygenic risk scores (PGT-P) is permitted in Singapore.Alexis Heng Boon Chin, Lee Wei Lim & Sayyed Mohamed Muhsin - forthcoming - Journal of Medical Ethics.
    Singapore, a highly affluent island city-state located in Southeast Asia, has increasingly leveraged new assisted reproductive technologies (ART) to overcome its dismal fertility rates in recent years. A new frontier in ART is preimplantation genetic testing (PGT) for polygenic risk scores (PRS) to predict complex multifactorial traits in IVF (in vitro fertilisation) embryos, such as type 2 diabetes, cardiovascular diseases and various other characteristics like height, intelligence quotient (IQ), hair and eye colour. Unlike well-known safety risks with human genome (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  31. Testing Sripada's Deep Self model.Florian Cova & Hichem Naar - 2012 - Philosophical Psychology 25 (5):647 - 659.
    Sripada has recently advanced a new account for asymmetries that have been uncovered in folk judgments of intentionality: the ?Deep Self model,? according to which an action is more likely to be judged as intentional if it matches the agent's central and stable attitudes and values (i.e., the agent's Deep Self). In this paper, we present new experiments that challenge this model in two ways: first, we show that the Deep Self model makes predictions that are falsified, then we present (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   10 citations  
  32.  34
    Supporting patient decision-making in non-invasive prenatal testing: a comparative study of professional values and practices in England and France.Hilary Bowman-Smart, Adeline Perrot & Ruth Horn - 2024 - BMC Medical Ethics 25 (1):1-13.
    Background Non-invasive prenatal testing (NIPT), which can screen for aneuploidies such as trisomy 21, is being implemented in several public healthcare systems across Europe. Comprehensive communication and information have been highlighted in the literature as important elements in supporting women’s reproductive decision-making and addressing relevant ethical concerns such as routinisation. Countries such as England and France are adopting broadly similar implementation models, offering NIPT for pregnancies with high aneuploidy probability. However, we do not have a deeper understanding of how (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  33.  68
    Testing Scientific Theories.John Earman (ed.) - 1983 - Minneapolis: University of Minnesota Press.
    Rich with historical and cultural value, these works are published unaltered from the original University of Minnesota Press editions.
    Direct download  
     
    Export citation  
     
    Bookmark   17 citations  
  34. A new paradigm for hypothesis testing in medicine, with examination of the Neyman Pearson condition.G. William Moore, Grover M. Hutchins & Robert E. Miller - 1986 - Theoretical Medicine and Bioethics 7 (3).
    In the past, hypothesis testing in medicine has employed the paradigm of the repeatable experiment. In statistical hypothesis testing, an unbiased sample is drawn from a larger source population, and a calculated statistic is compared to a preassigned critical region, on the assumption that the comparison could be repeated an indefinite number of times. However, repeated experiments often cannot be performed on human beings, due to ethical or economic constraints. We describe a new paradigm for hypothesis testing (...)
     
    Export citation  
     
    Bookmark  
  35. Design of a complex testing system for e-learning.Irina Noninska & Radi Romansky - 2007 - Communication and Cognition. Monographies 40 (1-2):113-118.
     
    Export citation  
     
    Bookmark  
  36.  42
    No consent for brain death testing.Thaddeus Mason Pope, Alexander Ruck Keene & Jennifer Chandler - 2024 - Journal of Medical Ethics 50 (7):494-495.
    The overwhelming weight of legal authority in the USA and Canada holds that consent is not required for brain death testing. The situation in England and Wales is similar but different. While clinicians in England and Wales may have a prima facie duty to obtain consent, lack of consent has not barred testing. In three recent cases where consent for brain death testing was formally presented to the court, lack of consent was not determinative, and in one (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  37.  70
    Testing the causal theory of reference.Filippo Domaneschi, Massimiliano Vignolo & Simona Di Paola - 2017 - Cognition 161 (C):1-9.
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   13 citations  
  38.  11
    Testing global memory models using ROC curves.Roger Ratcliff, Ching-fan Sheu & Scott D. Gronlund - 1992 - Psychological Review 99 (3):518-535.
  39.  18
    Decision-making about non-invasive prenatal testing: women’s moral reasoning in the absence of a risk of miscarriage in Germany.Stefan Reinsch, Anika König & Christoph Rehmann-Sutter - 2021 - New Genetics and Society 40 (2):199-215.
    This paper examines women’s experiences with decision-making about non-invasive prenatal testing (NIPT). Such tests offer knowledge about chromosomal disorders early in pregnancy, without the risk of miscarriage associated with invasive procedures such as amniocentesis. Based on qualitative interviews with women in Germany who used, or declined, NIPT, we show how some women, who would not consider amniocentesis due to the risk of miscarriage, welcome the knowledge provided by, and the additional agency resulting from, NIPT. For others, declining the offer (...)
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  40. Testing Pragmatic Genealogy in Political Theory: The Curious Case of John Rawls.Francesco Testini - 2022 - European Journal of Political Theory 21 (4):650-670.
    Starting from the ‘Dewey Lectures’, Rawls presents his conception of justice within a contextualist framework, as an elaboration of the basic ideas embedded in the political culture of liberal-democratic societies. But how are these basic ideas to be justified? In this article, I reconstruct and criticize Rawls’s strategy to answer this question. I explore an alternative strategy, consisting of a genealogical argument of a pragmatic kind – the kind of argument provided by authors like Bernard Williams, Edward Craig and Miranda (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   4 citations  
  41. Circles without Circularity, Testing Theories by Theory-laden Observations in An Intimate Relation. Studies in the History and Philosophy of Science.M. Carrier - 1989 - Boston Studies in the Philosophy of Science 116:405-428.
  42.  33
    Thinking Hypothetically about Hypothesis-Testing in the Humanities.E. M. Dadlez - 2015 - Southwest Philosophy Review 31 (1):21-28.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  43.  82
    REACH, animal testing, and the precautionary principle.Andre Menache & Candida Nastrucci - 2012 - Medicolegal and Bioethics:13.
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  44.  23
    Hypothesis testing and theory evaluation at the boundaries: Surprising insights from Bayes's theorem.David Trafimow - 2003 - Psychological Review 110 (3):526-535.
  45.  49
    Testing the Swerdlow/Koob model of schizophrena pathophysiology using positron emission tomography.Joseph C. Wu, Benjamin V. Siegel, Richard J. Haier & Monte S. Buchsbaum - 1990 - Behavioral and Brain Sciences 13 (1):168-170.
  46. Testing Scientific Theories.John Earman - 1988 - Philosophy of Science 55 (2):292-303.
     
    Export citation  
     
    Bookmark   17 citations  
  47.  66
    On testing the 'moral law'.Paulo Sousa - 2009 - Mind and Language 24 (2):209-234.
    Abstract: In a previous article in this journal, Daniel Kelly, Stephen Stich, Kevin Haley, Serena Eng and Daniel Fessler report data that, according to them, foster scepticism about an association between harm and morality existent in the Turiel tradition ( Kelly et al. , 2007 ). This article challenges their interpretation of the data. It does so by explicating some methodological problems in the Turiel tradition that Kelly et al. themselves in a way inherit and by drawing on new evidence (...)
    Direct download (6 more)  
     
    Export citation  
     
    Bookmark   20 citations  
  48.  35
    Women’s experiences with non-invasive prenatal testing in Switzerland: a qualitative analysis.Mirriam Tyebally Fang, Federico Germani, Giovanni Spitale, Sebastian Wäscher, Ladina Kunz & Nikola Biller-Andorno - 2023 - BMC Medical Ethics 24 (1):1-12.
    Background Prenatal genetic testing, in particular non-invasive prenatal testing (NIPT), as well as screening for risks associated with pregnancy, and counseling, play pivotal roles in reproductive healthcare, offering valuable information about the health of the fetus to expectant parents. This study aims to delve into the perspectives and experiences of women considering genetic testing and screening during pregnancy, focusing on their decision-making processes and the implications for informed consent. Methods A nationwide qualitative study was conducted in Switzerland, (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  49.  64
    Testing Design Bioethics Methods: Comparing a Digital Game with a Vignette Survey for Neuroethics Research with Young People.David M. Lyreskog, Gabriela Pavarini, Edward Jacobs, Vanessa Bennett, Geoffrey Mawdsley & Ilina Singh - 2023 - AJOB Empirical Bioethics 14 (1):55-64.
    Background Over the last decades, the neurosciences, behavioral sciences, and the social sciences have all seen a rapid development of innovative research methods. The field of bioethics, however, has trailed behind in methodological innovation. Despite the so-called “empirical turn” in bioethics, research methodology for project development, data collection and analysis, and dissemination has remained largely restricted to surveys, interviews, and research papers. We have previously argued for a “Design Bioethics” approach to empirical bioethics methodology, which develops purpose-built methods for investigation (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  50.  45
    Testing hypotheses in macroevolution.Lindell Bromham - 2016 - Studies in History and Philosophy of Science Part A 55:47-59.
1 — 50 / 970