Results for 'coagulation testing'

968 found
Order:
  1.  17
    Clustering of Thrombin Generation Test Data Using a Reduced Mathematical Model of Blood Coagulation.N. Ratto, A. Tokarev, P. Chelle, B. Tardy-Poncet & V. Volpert - 2019 - Acta Biotheoretica 68 (1):21-43.
    Correct interpretation of the data from integral laboratory tests, including Thrombin Generation Test, requires biochemistry-based mathematical models of blood coagulation. The purpose of this study is to describe the experimental TGT data from healthy donors and hemophilia A and B patients. We derive a simplified ODE model and apply it to analyze the TGT data from healthy donors and HA/HB patients with in vitro added tissue factor pathway inhibitor antibody. This model allows the characterization of hemophilia patients in the (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  2.  35
    Prevalence and type of pre‐analytical problems for inpatients samples in coagulation laboratory.Gian L. Salvagno, Giuseppe Lippi, Antonella Bassi, Giovanni Poli & Gian C. Guidi - 2008 - Journal of Evaluation in Clinical Practice 14 (2):351-353.
  3.  28
    Experimentation and theory choice: is thrombin an enzyme?James A. Marcum - 1996 - Perspectives on Science 4 (4):434-462.
    Approaches to the analysis of theory choice in science studies often focus either on objective criteria or subjective values for evaluating theories or on critical experiments for testing theories. In the present article a historical case study in the biomedical sciences is reconstructed, in which experimentation was performed to choose between two competing theories of blood coagulation. Analysis of this case study reveals that experimentation exhibits a particular structure, composed of design, execution, and results, and specific characteristics, consisting (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  4.  20
    Contrasting Medical and Legal Standards of Evidence: A Precision Medicine Case Study.Gary E. Marchant, Kathryn Scheckel & Doug Campos-Outcalt - 2016 - Journal of Law, Medicine and Ethics 44 (1):194-204.
    As the health care system transitions to a precision medicine approach that tailors clinical care to the genetic profile of the individual patient, there is a potential tension between the clinical uptake of new technologies by providers and the legal system's expectation of the standard of care in applying such technologies. We examine this tension by comparing the type of evidence that physicians and courts are likely to rely on in determining a duty to recommend pharmacogenetic testing of patients (...)
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  5. Magnet Wires Involved in Test Program As mentioned above, this paper will compare properties of six magnet wire types (imide-modified as well as con-ventional types) relative to use in hermetic motors; factors such as flexibility, abrasion resistance, heat shock, will not. In.A. Extractibles Test - 1968 - In Peter Koestenbaum, Proceedings. [San Jose? Calif.,: [San Jose? Calif.. pp. 127.
    No categories
     
    Export citation  
     
    Bookmark  
  6.  7
    Simone de Beauvoir: Le Refus de l'avenir. L'image de la femme dans Les Mandarins et Les Belles Images.Mary Lawrence Test - 1994 - Simone de Beauvoir Studies 11 (1):19-29.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  7.  9
    The Ephemera.Turing Test - 2004 - In Stuart M. Shieber, The Turing Test: Verbal Behavior as the Hallmark of Intelligence. MIT Press. pp. 97.
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark  
  8. Joseph R. Des jardins and Ronald Duska.Drug Testing in Employment 100 - 2003 - In William H. Shaw, Ethics at work: basic readings in business ethics. New York: Oxford University Press.
     
    Export citation  
     
    Bookmark  
  9.  15
    From Moscow to Chicago and Back: Simone de Beauvoir, Political Peripatetic.Mary Lawrence Test & Myrna Bell Rochester - 1995 - Simone de Beauvoir Studies 12 (1):59-72.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  10.  15
    Tony Judt’s Intellectuals and the Very Last of the Enlightenment.Mary Lawrence Test - 1993 - Simone de Beauvoir Studies 10 (1):285-288.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  11.  9
    Hazel Rowley’s Tête-à-Tête: Simone de Beauvoir and Jean-Paul Sartre.Mary Lawrence Test & Myrna Bell Rochester - 2006 - Simone de Beauvoir Studies 22 (1):92-94.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  12.  11
    The Politics of Violence and the Violence of Politics in the Works of Simone de Beauvoir.Myrna Bell Rochester & Mary Lawrence Test - 1996 - Simone de Beauvoir Studies 13 (1):184-201.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  13.  7
    Why and How We Should Read Beauvoir Today and What We Can Learn from Our Reading.Myrna Bell Rochester & Mary Lawrence Test - 2007 - Simone de Beauvoir Studies 23 (1):91-95.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  14. Critical period, 241-242.Implications Test - 1997 - In M. McCallum & W. Piper, Psychological Mindedness: A Contemporary Understanding. Lawrence Erlbaum. pp. 59--271.
  15.  7
    In Memoriam: Béatrix Beck.Susan Petit, Myrna Bell Rochester & Mary Lawrence Test - 2009 - Simone de Beauvoir Studies 25 (1):102-106.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  16. Entrapment, temptation and virtue testing.Daniel J. Hill, Stephen K. McLeod & Attila Tanyi - 2022 - Philosophical Studies 179 (8):2429–2447.
    We address the ethics of scenarios in which one party entraps, intentionally tempts or intentionally tests the virtue of another. We classify, in a new manner, three distinct types of acts that are of concern, namely acts of entrapment, of intentional temptation and of virtue testing. Our classification is, for each kind of scenario, of itself neutral concerning the question whether the agent acts permissibly. We explain why acts of entrapment are more ethically objectionable than like acts of intentional (...)
    Direct download (6 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  17.  80
    Non-Invasive Prenatal Testing for “Non-Medical” Traits: Ensuring Consistency in Ethical Decision-Making.Hilary Bowman-Smart, Christopher Gyngell, Cara Mand, David J. Amor, Martin B. Delatycki & Julian Savulescu - 2021 - American Journal of Bioethics 23 (3):3-20.
    The scope of noninvasive prenatal testing (NIPT) could expand in the future to include detailed analysis of the fetal genome. This will allow for the testing for virtually any trait with a genetic contribution, including “non-medical” traits. Here we discuss the potential use of NIPT for these traits. We outline a scenario which highlights possible inconsistencies with ethical decision-making. We then discuss the case against permitting these uses. The objections include practical problems; increasing inequities; increasing the burden of (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   18 citations  
  18.  69
    Theory testing in science—the case of solar neutrinos: Do crucial experiments test theories or theorists?Trevor Pinch - 1985 - Philosophy of the Social Sciences 15 (2):167-187.
  19.  59
    How do parents decide on genetic testing in pediatrics? A systematic review.Elena Sophia Doll, Seraina Petra Lerch, Katja Maria Schmalenberger, Karla Alex, Stefan Kölker, Heiko Brennenstuhl, Stacey Pereira, Hadley Smith, Eva C. Winkler, Julia Mahal & Beate Ditzen - forthcoming - Genetics in Medicine.
    Purpose This systematic review aims to identify factors that influence parents’ decisions regarding pediatric diagnostic and predictive genetic testing (DT/PT). Factors are integrated into a conceptual model of decision-making. Implications for genetic counseling, research, and ethics are derived. Methods PubMed, PsychInfo, WebofScience and references of related reviews were searched for original publications between 2000 and 2023. Extracted factors were categorized into an existing model. Results Of 5843 publications, 56 met inclusion criteria. The included studies differentiate between DT, traditional, and (...)
    Direct download  
     
    Export citation  
     
    Bookmark  
  20.  9
    Esthetics in Action: The Operative Limits of Committed Fiction.Myrna Bell Rochester & Mary Lawrence Test - 1993 - Simone de Beauvoir Studies 10 (1):91-114.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  21.  49
    Testing Ordinary Meaning.Kevin Tobia - 2020 - Harvard Law Review 134.
    Within legal scholarship and practice, among the most pervasive tasks is the interpretation of texts. And within legal interpretation, perhaps the most pervasive inquiry is the search for “ordinary meaning.” Jurists often treat ordinary meaning analysis as an empirical inquiry, aiming to discover a fact about how people understand language. When evaluating ordinary meaning, interpreters rely on dictionary definitions or patterns of common usage, increasingly via “legal corpus linguistics” approaches. However, the most central question about these popular methods remains open: (...)
    Direct download  
     
    Export citation  
     
    Bookmark   8 citations  
  22.  58
    Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?Michelle J. Bayefsky & Benjamin E. Berkman - 2022 - American Journal of Bioethics 22 (2):4-22.
    Prenatal genetic testing is becoming available for an increasingly broad set of diseases, and it is only a matter of time before parents can choose to test for hundreds, if not thousands, of genetic conditions in their fetuses. Should access to certain kinds of fetal genetic information be limited, and if so, on what basis? We evaluate a range of considerations including reproductive autonomy, parental rights, disability rights, and the rights and interests of the fetus as a potential future (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   17 citations  
  23. Theory-testing in psychology and physics: A methodological paradox.Paul E. Meehl - 1967 - Philosophy of Science 34 (2):103-115.
    Because physical theories typically predict numerical values, an improvement in experimental precision reduces the tolerance range and hence increases corroborability. In most psychological research, improved power of a statistical design leads to a prior probability approaching 1/2 of finding a significant difference in the theoretically predicted direction. Hence the corroboration yielded by "success" is very weak, and becomes weaker with increased precision. "Statistical significance" plays a logical role in psychology precisely the reverse of its role in physics. This problem is (...)
    Direct download (8 more)  
     
    Export citation  
     
    Bookmark   61 citations  
  24. On Testing for Conversational Implicature.Jerrold M. Sadock - 1978 - In Peter Cole, Syntax and Semantics: Pragmatics. Academic Press. pp. 281–297.
     
    Export citation  
     
    Bookmark   73 citations  
  25.  34
    Empowerment through health self-testing apps? Revisiting empowerment as a process.Alexandra Kapeller & Iris Loosman - 2023 - Medicine, Health Care and Philosophy 26 (1):143-152.
    Empowerment, an already central concept in public health, has gained additional relevance through the expansion of mobile health (mHealth). Especially direct-to-consumer self-testing app companies mobilise the term to advertise their products, which allow users to self-test for various medical conditions independent of healthcare professionals. This article first demonstrates the absence of empowerment conceptualisations in the context of self-testing apps by engaging with empowerment literature. It then contrasts the service these apps provide with two widely cited empowerment definitions by (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   7 citations  
  26. Panum area testing in human fovea.Y. Loginovich, A. Bulatov & A. Bertulis - 1996 - In Enrique Villanueva, Perception. Ridgeview Pub. Co. pp. 90-90.
     
    Export citation  
     
    Bookmark  
  27. Predictive genetic testing in children: where are we now? An overview and a UK perspective.A. Lucassen & J. Montgomery - unknown
     
    Export citation  
     
    Bookmark   1 citation  
  28. Hypothesis testing: The role of confirmation.R. D. Tweney, M. E. Doherty & C. R. Mynatt - 1981 - In Ryan D. Tweney, Michael E. Doherty & Clifford R. Mynatt, On scientific thinking. New York: Columbia University Press. pp. 115--128.
     
    Export citation  
     
    Bookmark   59 citations  
  29. Access to Prenatal Testing and Ethically Informed Counselling in Germany, Poland and Russia.Marcin Orzechowski, Cristian Timmermann, Katarzyna Woniak, Oxana Kosenko, Galina Lvovna Mikirtichan, Alexandr Zinovievich Lichtshangof & Florian Steger - 2021 - Journal of Personalized Medicine 11 (9):937.
    The development of new methods in the field of prenatal testing leads to an expansion of information that needs to be provided to expectant mothers. The aim of this research is to explore opinions and attitudes of gynecologists in Germany, Poland and Russia towards access to prenatal testing and diagnostics in these countries. Semi-structured interviews were conducted with n = 18 gynecologists in Germany, Poland and Russia. The interviews were analyzed using the methods of content analysis and thematic (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  30.  16
    Simone de Beauvoir: Living Through Conflict.Myrna Bell Rochester & Mary Lawrence Test - 1992 - Simone de Beauvoir Studies 9 (1):17-30.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  31. A new paradigm for hypothesis testing in medicine, with examination of the Neyman Pearson condition.G. William Moore, Grover M. Hutchins & Robert E. Miller - 1986 - Theoretical Medicine and Bioethics 7 (3).
    In the past, hypothesis testing in medicine has employed the paradigm of the repeatable experiment. In statistical hypothesis testing, an unbiased sample is drawn from a larger source population, and a calculated statistic is compared to a preassigned critical region, on the assumption that the comparison could be repeated an indefinite number of times. However, repeated experiments often cannot be performed on human beings, due to ethical or economic constraints. We describe a new paradigm for hypothesis testing (...)
     
    Export citation  
     
    Bookmark  
  32.  11
    In Memoriam: Dominque Desanti (1919-2011), “Forty plus years of friendship, thanks to Simone de Beauvoir”.Myrna Bell Rochester & Mary Lawrence Test - 2011 - Simone de Beauvoir Studies 27 (1):93-96.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  33. Testing Sripada's Deep Self model.Florian Cova & Hichem Naar - 2012 - Philosophical Psychology 25 (5):647 - 659.
    Sripada has recently advanced a new account for asymmetries that have been uncovered in folk judgments of intentionality: the ?Deep Self model,? according to which an action is more likely to be judged as intentional if it matches the agent's central and stable attitudes and values (i.e., the agent's Deep Self). In this paper, we present new experiments that challenge this model in two ways: first, we show that the Deep Self model makes predictions that are falsified, then we present (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   10 citations  
  34.  26
    Islamic Perspectives on Polygenic Testing and Selection of IVF Embryos (PGT-P) for Optimal Intelligence and Other Non–Disease-Related Socially Desirable Traits.A. H. B. Chin, Q. Al-Balas, M. F. Ahmad, N. Alsomali & M. Ghaly - 2024 - Journal of Bioethical Inquiry 21 (3):441-448.
    In recent years, the genetic testing and selection of IVF embryos, known as preimplantation genetic testing (PGT), has gained much traction in clinical assisted reproduction for preventing transmission of genetic defects. However, a more recent ethically and morally controversial development in PGT is its possible use in selecting IVF embryos for optimal intelligence quotient (IQ) and other non–disease-related socially desirable traits, such as tallness, fair complexion, athletic ability, and eye and hair colour, based on polygenic risk scores (PRS), (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   5 citations  
  35.  68
    Testing Scientific Theories.John Earman (ed.) - 1983 - Minneapolis: University of Minnesota Press.
    Rich with historical and cultural value, these works are published unaltered from the original University of Minnesota Press editions.
    Direct download  
     
    Export citation  
     
    Bookmark   17 citations  
  36.  84
    Testing the underlying structure of unfounded beliefs about COVID-19 around the world.Paweł Brzóska, Magdalena Żemojtel-Piotrowska, Jarosław Piotrowski, Bartłomiej Nowak, Peter K. Jonason, Constantine Sedikides, Mladen Adamovic, Kokou A. Atitsogbe, Oli Ahmed, Uzma Azam, Sergiu Bălțătescu, Konstantin Bochaver, Aidos Bolatov, Mario Bonato, Victor Counted, Trawin Chaleeraktrakoon, Jano Ramos-Diaz, Sonya Dragova-Koleva, Walaa Labib M. Eldesoki, Carla Sofia Esteves, Valdiney V. Gouveia, Pablo Perez de Leon, Dzintra Iliško, Jesus Alfonso D. Datu, Fanli Jia, Veljko Jovanović, Tomislav Jukić, Narine Khachatryan, Monika Kovacs, Uri Lifshin, Aitor Larzabal Fernandez, Kadi Liik, Sadia Malik, Chanki Moon, Stephan Muehlbacher, Reza Najafi, Emre Oruç, Joonha Park, Iva Poláčková Šolcová, Rahkman Ardi, Ognjen Ridic, Goran Ridic, Yadgar Ismail Said, Andrej Starc, Delia Stefenel, Kiều Thị Thanh Trà, Habib Tiliouine, Robert Tomšik, Jorge Torres-Marin, Charles S. Umeh, Eduardo Wills-Herrera, Anna Wlodarczyk, Zahir Vally & Illia Yahiiaiev - 2023 - Thinking and Reasoning 30 (2):301-326.
    Unfounded—conspiracy and health—beliefs about COVID-19 have accompanied the pandemic worldwide. Here, we examined cross-nationally the structure and correlates of these beliefs with an 8-item scale, using a multigroup confirmatory factor analysis. We obtained a two-factor model of unfounded (conspiracy and health) beliefs with good internal structure (average CFI = 0.98, RMSEA = 0.05, SRMR = 0.04), but a high correlation between the two factors (average latent factor correlation = 0.57). This model was replicable across 50 countries (total N = 13,579), (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  37.  39
    Pediatric Brain Death Testing Over Parental Objections: Not an Ethically Preferable Option.Jonathan M. Marron - 2023 - American Journal of Bioethics 23 (1):90-93.
    In many ways, Maddie’s case brings together some of the most challenging features seen in clinical ethics consultation. First, it centers around a heart-wrenching event—the near-drowning of a young...
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  38.  70
    Testing the causal theory of reference.Filippo Domaneschi, Massimiliano Vignolo & Simona Di Paola - 2017 - Cognition 161 (C):1-9.
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   13 citations  
  39.  82
    REACH, animal testing, and the precautionary principle.Andre Menache & Candida Nastrucci - 2012 - Medicolegal and Bioethics:13.
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  40.  47
    Consent to testing for brain death.Barry Lyons & Mary Donnelly - 2024 - Journal of Medical Ethics 50 (7):442-446.
    Canada has recently published a new Clinical Practice Guideline on the diagnosis and management of brain death. It states that consent is not necessary to carry out the interventions required to make the diagnosis. A supporting article not only sets out the arguments for this but also contends that ‘UK laws similarly carve out an exception, excusing clinicians from a prima facie duty to get consent’. This is supplemented by the claim that recent court decisions in the UK similarly confirm (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  41.  32
    Testing Definitional Equivalence of Theories Via Automorphism Groups.Hajnal Andréka, Judit Madarász, István Németi & Gergely Székely - 2024 - Review of Symbolic Logic 17 (4):1097-1118.
    Two first-order logic theories are definitionally equivalent if and only if there is a bijection between their model classes that preserves isomorphisms and ultraproducts (Theorem 2). This is a variant of a prior theorem of van Benthem and Pearce. In Example 2, uncountably many pairs of definitionally inequivalent theories are given such that their model categories are concretely isomorphic via bijections that preserve ultraproducts in the model categories up to isomorphism. Based on these results, we settle several conjectures of Barrett, (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  42.  17
    Non-invasive Prenatal Testing for Fetal Whole Genome Sequencing: An Interpretive Critical Review of the Ethical, Legal, Social, and Policy Implications.Hazar Haidar & Renata Iskander - 2022 - Canadian Journal of Bioethics / Revue canadienne de bioéthique 5 (1):1-15.
    Introduction: Non-invasive prenatal testing (NIPT) allows for genetic testing of a fetus through the analysis of cell-free DNA from the mother’s plasma. NIPT is easy and safe for the fetus, since it only requires a blood draw from the mother and therefore holds no risk of miscarriage. It is considered superior to other prenatal screening tests and can also be performed earlier in the pregnancy. NIPT has the future potential for fetal whole genome sequencing (FWGS) for an expanded (...)
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  43.  27
    HIV testing and mental disorder.Simon Lundy - 1989 - Journal of Medical Ethics 15 (2):92-93.
  44.  22
    Selecting and Testing Environmental Enrichment in Lemurs.Eduardo J. Fernandez & William Timberlake - 2019 - Frontiers in Psychology 10.
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  45.  40
    Chow's defense of Null-hypothesis testing: Too traditional?Robert W. Frick - 1998 - Behavioral and Brain Sciences 21 (2):199-199.
    I disagree with several of Chow's traditional descriptions and justifications of null hypothesis testing: (1) accepting the null hypothesis whenever p > .05; (2) random sampling from a population; (3) the frequentist interpretation of probability; (4) having the null hypothesis generate both a probability distribution and a complement of the desired conclusion; (5) assuming that researchers must fix their sample size before performing their study.
    Direct download (7 more)  
     
    Export citation  
     
    Bookmark  
  46.  11
    Testing global memory models using ROC curves.Roger Ratcliff, Ching-fan Sheu & Scott D. Gronlund - 1992 - Psychological Review 99 (3):518-535.
  47. Statistical Significance Testing in Economics.William Peden & Jan Sprenger - 2022 - In Conrad Heilmann & Julian Reiss, Routledge Handbook of Philosophy of Economics. Routledge.
    The origins of testing scientific models with statistical techniques go back to 18th century mathematics. However, the modern theory of statistical testing was primarily developed through the work of Sir R.A. Fisher, Jerzy Neyman, and Egon Pearson in the inter-war period. Some of Fisher's papers on testing were published in economics journals (Fisher, 1923, 1935) and exerted a notable influence on the discipline. The development of econometrics and the rise of quantitative economic models in the mid-20th century (...)
    Direct download  
     
    Export citation  
     
    Bookmark  
  48. Testing Pragmatic Genealogy in Political Theory: The Curious Case of John Rawls.Francesco Testini - 2022 - European Journal of Political Theory 21 (4):650-670.
    Starting from the ‘Dewey Lectures’, Rawls presents his conception of justice within a contextualist framework, as an elaboration of the basic ideas embedded in the political culture of liberal-democratic societies. But how are these basic ideas to be justified? In this article, I reconstruct and criticize Rawls’s strategy to answer this question. I explore an alternative strategy, consisting of a genealogical argument of a pragmatic kind – the kind of argument provided by authors like Bernard Williams, Edward Craig and Miranda (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   4 citations  
  49. Circles without Circularity, Testing Theories by Theory-laden Observations in An Intimate Relation. Studies in the History and Philosophy of Science.M. Carrier - 1989 - Boston Studies in the Philosophy of Science 116:405-428.
  50.  33
    Thinking Hypothetically about Hypothesis-Testing in the Humanities.E. M. Dadlez - 2015 - Southwest Philosophy Review 31 (1):21-28.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
1 — 50 / 968