Results for 'coagulation testing'

970 found
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  1.  17
    Clustering of Thrombin Generation Test Data Using a Reduced Mathematical Model of Blood Coagulation.N. Ratto, A. Tokarev, P. Chelle, B. Tardy-Poncet & V. Volpert - 2019 - Acta Biotheoretica 68 (1):21-43.
    Correct interpretation of the data from integral laboratory tests, including Thrombin Generation Test, requires biochemistry-based mathematical models of blood coagulation. The purpose of this study is to describe the experimental TGT data from healthy donors and hemophilia A and B patients. We derive a simplified ODE model and apply it to analyze the TGT data from healthy donors and HA/HB patients with in vitro added tissue factor pathway inhibitor antibody. This model allows the characterization of hemophilia patients in the (...)
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  2.  35
    Prevalence and type of pre‐analytical problems for inpatients samples in coagulation laboratory.Gian L. Salvagno, Giuseppe Lippi, Antonella Bassi, Giovanni Poli & Gian C. Guidi - 2008 - Journal of Evaluation in Clinical Practice 14 (2):351-353.
  3.  28
    Experimentation and theory choice: is thrombin an enzyme?James A. Marcum - 1996 - Perspectives on Science 4 (4):434-462.
    Approaches to the analysis of theory choice in science studies often focus either on objective criteria or subjective values for evaluating theories or on critical experiments for testing theories. In the present article a historical case study in the biomedical sciences is reconstructed, in which experimentation was performed to choose between two competing theories of blood coagulation. Analysis of this case study reveals that experimentation exhibits a particular structure, composed of design, execution, and results, and specific characteristics, consisting (...)
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  4.  20
    Contrasting Medical and Legal Standards of Evidence: A Precision Medicine Case Study.Gary E. Marchant, Kathryn Scheckel & Doug Campos-Outcalt - 2016 - Journal of Law, Medicine and Ethics 44 (1):194-204.
    As the health care system transitions to a precision medicine approach that tailors clinical care to the genetic profile of the individual patient, there is a potential tension between the clinical uptake of new technologies by providers and the legal system's expectation of the standard of care in applying such technologies. We examine this tension by comparing the type of evidence that physicians and courts are likely to rely on in determining a duty to recommend pharmacogenetic testing of patients (...)
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  5. Magnet Wires Involved in Test Program As mentioned above, this paper will compare properties of six magnet wire types (imide-modified as well as con-ventional types) relative to use in hermetic motors; factors such as flexibility, abrasion resistance, heat shock, will not. In.A. Extractibles Test - 1968 - In Peter Koestenbaum, Proceedings. [San Jose? Calif.,: [San Jose? Calif.. pp. 127.
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  6.  7
    Simone de Beauvoir: Le Refus de l'avenir. L'image de la femme dans Les Mandarins et Les Belles Images.Mary Lawrence Test - 1994 - Simone de Beauvoir Studies 11 (1):19-29.
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  7.  9
    The Ephemera.Turing Test - 2004 - In Stuart M. Shieber, The Turing Test: Verbal Behavior as the Hallmark of Intelligence. MIT Press. pp. 97.
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  8. Joseph R. Des jardins and Ronald Duska.Drug Testing in Employment 100 - 2003 - In William H. Shaw, Ethics at work: basic readings in business ethics. New York: Oxford University Press.
     
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  9.  15
    Tony Judt’s Intellectuals and the Very Last of the Enlightenment.Mary Lawrence Test - 1993 - Simone de Beauvoir Studies 10 (1):285-288.
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  10.  15
    From Moscow to Chicago and Back: Simone de Beauvoir, Political Peripatetic.Mary Lawrence Test & Myrna Bell Rochester - 1995 - Simone de Beauvoir Studies 12 (1):59-72.
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  11.  9
    Hazel Rowley’s Tête-à-Tête: Simone de Beauvoir and Jean-Paul Sartre.Mary Lawrence Test & Myrna Bell Rochester - 2006 - Simone de Beauvoir Studies 22 (1):92-94.
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  12. Critical period, 241-242.Implications Test - 1997 - In M. McCallum & W. Piper, Psychological Mindedness: A Contemporary Understanding. Lawrence Erlbaum. pp. 59--271.
  13.  11
    The Politics of Violence and the Violence of Politics in the Works of Simone de Beauvoir.Myrna Bell Rochester & Mary Lawrence Test - 1996 - Simone de Beauvoir Studies 13 (1):184-201.
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  14.  7
    Why and How We Should Read Beauvoir Today and What We Can Learn from Our Reading.Myrna Bell Rochester & Mary Lawrence Test - 2007 - Simone de Beauvoir Studies 23 (1):91-95.
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  15.  47
    Consent to testing for brain death.Barry Lyons & Mary Donnelly - 2024 - Journal of Medical Ethics 50 (7):442-446.
    Canada has recently published a new Clinical Practice Guideline on the diagnosis and management of brain death. It states that consent is not necessary to carry out the interventions required to make the diagnosis. A supporting article not only sets out the arguments for this but also contends that ‘UK laws similarly carve out an exception, excusing clinicians from a prima facie duty to get consent’. This is supplemented by the claim that recent court decisions in the UK similarly confirm (...)
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  16. Entrapment, temptation and virtue testing.Daniel J. Hill, Stephen K. McLeod & Attila Tanyi - 2022 - Philosophical Studies 179 (8):2429–2447.
    We address the ethics of scenarios in which one party entraps, intentionally tempts or intentionally tests the virtue of another. We classify, in a new manner, three distinct types of acts that are of concern, namely acts of entrapment, of intentional temptation and of virtue testing. Our classification is, for each kind of scenario, of itself neutral concerning the question whether the agent acts permissibly. We explain why acts of entrapment are more ethically objectionable than like acts of intentional (...)
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  17.  80
    Non-Invasive Prenatal Testing for “Non-Medical” Traits: Ensuring Consistency in Ethical Decision-Making.Hilary Bowman-Smart, Christopher Gyngell, Cara Mand, David J. Amor, Martin B. Delatycki & Julian Savulescu - 2021 - American Journal of Bioethics 23 (3):3-20.
    The scope of noninvasive prenatal testing (NIPT) could expand in the future to include detailed analysis of the fetal genome. This will allow for the testing for virtually any trait with a genetic contribution, including “non-medical” traits. Here we discuss the potential use of NIPT for these traits. We outline a scenario which highlights possible inconsistencies with ethical decision-making. We then discuss the case against permitting these uses. The objections include practical problems; increasing inequities; increasing the burden of (...)
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  18.  9
    Esthetics in Action: The Operative Limits of Committed Fiction.Myrna Bell Rochester & Mary Lawrence Test - 1993 - Simone de Beauvoir Studies 10 (1):91-114.
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  19.  69
    Theory testing in science—the case of solar neutrinos: Do crucial experiments test theories or theorists?Trevor Pinch - 1985 - Philosophy of the Social Sciences 15 (2):167-187.
  20.  58
    Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?Michelle J. Bayefsky & Benjamin E. Berkman - 2022 - American Journal of Bioethics 22 (2):4-22.
    Prenatal genetic testing is becoming available for an increasingly broad set of diseases, and it is only a matter of time before parents can choose to test for hundreds, if not thousands, of genetic conditions in their fetuses. Should access to certain kinds of fetal genetic information be limited, and if so, on what basis? We evaluate a range of considerations including reproductive autonomy, parental rights, disability rights, and the rights and interests of the fetus as a potential future (...)
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  21. Theory-testing in psychology and physics: A methodological paradox.Paul E. Meehl - 1967 - Philosophy of Science 34 (2):103-115.
    Because physical theories typically predict numerical values, an improvement in experimental precision reduces the tolerance range and hence increases corroborability. In most psychological research, improved power of a statistical design leads to a prior probability approaching 1/2 of finding a significant difference in the theoretically predicted direction. Hence the corroboration yielded by "success" is very weak, and becomes weaker with increased precision. "Statistical significance" plays a logical role in psychology precisely the reverse of its role in physics. This problem is (...)
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  22. On Testing for Conversational Implicature.Jerrold M. Sadock - 1978 - In Peter Cole, Syntax and Semantics: Pragmatics. Academic Press. pp. 281–297.
     
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  23.  7
    In Memoriam: Béatrix Beck.Susan Petit, Myrna Bell Rochester & Mary Lawrence Test - 2009 - Simone de Beauvoir Studies 25 (1):102-106.
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  24.  34
    Empowerment through health self-testing apps? Revisiting empowerment as a process.Alexandra Kapeller & Iris Loosman - 2023 - Medicine, Health Care and Philosophy 26 (1):143-152.
    Empowerment, an already central concept in public health, has gained additional relevance through the expansion of mobile health (mHealth). Especially direct-to-consumer self-testing app companies mobilise the term to advertise their products, which allow users to self-test for various medical conditions independent of healthcare professionals. This article first demonstrates the absence of empowerment conceptualisations in the context of self-testing apps by engaging with empowerment literature. It then contrasts the service these apps provide with two widely cited empowerment definitions by (...)
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  25.  16
    Simone de Beauvoir: Living Through Conflict.Myrna Bell Rochester & Mary Lawrence Test - 1992 - Simone de Beauvoir Studies 9 (1):17-30.
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  26. Hypothesis testing: The role of confirmation.R. D. Tweney, M. E. Doherty & C. R. Mynatt - 1981 - In Ryan D. Tweney, Michael E. Doherty & Clifford R. Mynatt, On scientific thinking. New York: Columbia University Press. pp. 115--128.
     
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  27. Access to Prenatal Testing and Ethically Informed Counselling in Germany, Poland and Russia.Marcin Orzechowski, Cristian Timmermann, Katarzyna Woniak, Oxana Kosenko, Galina Lvovna Mikirtichan, Alexandr Zinovievich Lichtshangof & Florian Steger - 2021 - Journal of Personalized Medicine 11 (9):937.
    The development of new methods in the field of prenatal testing leads to an expansion of information that needs to be provided to expectant mothers. The aim of this research is to explore opinions and attitudes of gynecologists in Germany, Poland and Russia towards access to prenatal testing and diagnostics in these countries. Semi-structured interviews were conducted with n = 18 gynecologists in Germany, Poland and Russia. The interviews were analyzed using the methods of content analysis and thematic (...)
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  28.  11
    In Memoriam: Dominque Desanti (1919-2011), “Forty plus years of friendship, thanks to Simone de Beauvoir”.Myrna Bell Rochester & Mary Lawrence Test - 2011 - Simone de Beauvoir Studies 27 (1):93-96.
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  29.  26
    Islamic Perspectives on Polygenic Testing and Selection of IVF Embryos (PGT-P) for Optimal Intelligence and Other Non–Disease-Related Socially Desirable Traits.A. H. B. Chin, Q. Al-Balas, M. F. Ahmad, N. Alsomali & M. Ghaly - 2024 - Journal of Bioethical Inquiry 21 (3):441-448.
    In recent years, the genetic testing and selection of IVF embryos, known as preimplantation genetic testing (PGT), has gained much traction in clinical assisted reproduction for preventing transmission of genetic defects. However, a more recent ethically and morally controversial development in PGT is its possible use in selecting IVF embryos for optimal intelligence quotient (IQ) and other non–disease-related socially desirable traits, such as tallness, fair complexion, athletic ability, and eye and hair colour, based on polygenic risk scores (PRS), (...)
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  30. Testing Sripada's Deep Self model.Florian Cova & Hichem Naar - 2012 - Philosophical Psychology 25 (5):647 - 659.
    Sripada has recently advanced a new account for asymmetries that have been uncovered in folk judgments of intentionality: the ?Deep Self model,? according to which an action is more likely to be judged as intentional if it matches the agent's central and stable attitudes and values (i.e., the agent's Deep Self). In this paper, we present new experiments that challenge this model in two ways: first, we show that the Deep Self model makes predictions that are falsified, then we present (...)
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  31.  68
    Testing Scientific Theories.John Earman (ed.) - 1983 - Minneapolis: University of Minnesota Press.
    Rich with historical and cultural value, these works are published unaltered from the original University of Minnesota Press editions.
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  32. A new paradigm for hypothesis testing in medicine, with examination of the Neyman Pearson condition.G. William Moore, Grover M. Hutchins & Robert E. Miller - 1986 - Theoretical Medicine and Bioethics 7 (3).
    In the past, hypothesis testing in medicine has employed the paradigm of the repeatable experiment. In statistical hypothesis testing, an unbiased sample is drawn from a larger source population, and a calculated statistic is compared to a preassigned critical region, on the assumption that the comparison could be repeated an indefinite number of times. However, repeated experiments often cannot be performed on human beings, due to ethical or economic constraints. We describe a new paradigm for hypothesis testing (...)
     
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  33. Design of a complex testing system for e-learning.Irina Noninska & Radi Romansky - 2007 - Communication and Cognition. Monographies 40 (1-2):113-118.
     
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  34.  84
    Testing the underlying structure of unfounded beliefs about COVID-19 around the world.Paweł Brzóska, Magdalena Żemojtel-Piotrowska, Jarosław Piotrowski, Bartłomiej Nowak, Peter K. Jonason, Constantine Sedikides, Mladen Adamovic, Kokou A. Atitsogbe, Oli Ahmed, Uzma Azam, Sergiu Bălțătescu, Konstantin Bochaver, Aidos Bolatov, Mario Bonato, Victor Counted, Trawin Chaleeraktrakoon, Jano Ramos-Diaz, Sonya Dragova-Koleva, Walaa Labib M. Eldesoki, Carla Sofia Esteves, Valdiney V. Gouveia, Pablo Perez de Leon, Dzintra Iliško, Jesus Alfonso D. Datu, Fanli Jia, Veljko Jovanović, Tomislav Jukić, Narine Khachatryan, Monika Kovacs, Uri Lifshin, Aitor Larzabal Fernandez, Kadi Liik, Sadia Malik, Chanki Moon, Stephan Muehlbacher, Reza Najafi, Emre Oruç, Joonha Park, Iva Poláčková Šolcová, Rahkman Ardi, Ognjen Ridic, Goran Ridic, Yadgar Ismail Said, Andrej Starc, Delia Stefenel, Kiều Thị Thanh Trà, Habib Tiliouine, Robert Tomšik, Jorge Torres-Marin, Charles S. Umeh, Eduardo Wills-Herrera, Anna Wlodarczyk, Zahir Vally & Illia Yahiiaiev - 2023 - Thinking and Reasoning 30 (2):301-326.
    Unfounded—conspiracy and health—beliefs about COVID-19 have accompanied the pandemic worldwide. Here, we examined cross-nationally the structure and correlates of these beliefs with an 8-item scale, using a multigroup confirmatory factor analysis. We obtained a two-factor model of unfounded (conspiracy and health) beliefs with good internal structure (average CFI = 0.98, RMSEA = 0.05, SRMR = 0.04), but a high correlation between the two factors (average latent factor correlation = 0.57). This model was replicable across 50 countries (total N = 13,579), (...)
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  35.  70
    Testing the causal theory of reference.Filippo Domaneschi, Massimiliano Vignolo & Simona Di Paola - 2017 - Cognition 161 (C):1-9.
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  36.  32
    Testing Definitional Equivalence of Theories Via Automorphism Groups.Hajnal Andréka, Judit Madarász, István Németi & Gergely Székely - 2024 - Review of Symbolic Logic 17 (4):1097-1118.
    Two first-order logic theories are definitionally equivalent if and only if there is a bijection between their model classes that preserves isomorphisms and ultraproducts (Theorem 2). This is a variant of a prior theorem of van Benthem and Pearce. In Example 2, uncountably many pairs of definitionally inequivalent theories are given such that their model categories are concretely isomorphic via bijections that preserve ultraproducts in the model categories up to isomorphism. Based on these results, we settle several conjectures of Barrett, (...)
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  37.  11
    Testing global memory models using ROC curves.Roger Ratcliff, Ching-fan Sheu & Scott D. Gronlund - 1992 - Psychological Review 99 (3):518-535.
  38. Testing Pragmatic Genealogy in Political Theory: The Curious Case of John Rawls.Francesco Testini - 2022 - European Journal of Political Theory 21 (4):650-670.
    Starting from the ‘Dewey Lectures’, Rawls presents his conception of justice within a contextualist framework, as an elaboration of the basic ideas embedded in the political culture of liberal-democratic societies. But how are these basic ideas to be justified? In this article, I reconstruct and criticize Rawls’s strategy to answer this question. I explore an alternative strategy, consisting of a genealogical argument of a pragmatic kind – the kind of argument provided by authors like Bernard Williams, Edward Craig and Miranda (...)
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  39.  82
    REACH, animal testing, and the precautionary principle.Andre Menache & Candida Nastrucci - 2012 - Medicolegal and Bioethics:13.
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  40.  23
    Hypothesis testing and theory evaluation at the boundaries: Surprising insights from Bayes's theorem.David Trafimow - 2003 - Psychological Review 110 (3):526-535.
  41.  49
    Testing the Swerdlow/Koob model of schizophrena pathophysiology using positron emission tomography.Joseph C. Wu, Benjamin V. Siegel, Richard J. Haier & Monte S. Buchsbaum - 1990 - Behavioral and Brain Sciences 13 (1):168-170.
  42. Testing Scientific Theories.John Earman - 1988 - Philosophy of Science 55 (2):292-303.
     
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  43.  66
    On testing the 'moral law'.Paulo Sousa - 2009 - Mind and Language 24 (2):209-234.
    Abstract: In a previous article in this journal, Daniel Kelly, Stephen Stich, Kevin Haley, Serena Eng and Daniel Fessler report data that, according to them, foster scepticism about an association between harm and morality existent in the Turiel tradition ( Kelly et al. , 2007 ). This article challenges their interpretation of the data. It does so by explicating some methodological problems in the Turiel tradition that Kelly et al. themselves in a way inherit and by drawing on new evidence (...)
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  44.  64
    Testing Design Bioethics Methods: Comparing a Digital Game with a Vignette Survey for Neuroethics Research with Young People.David M. Lyreskog, Gabriela Pavarini, Edward Jacobs, Vanessa Bennett, Geoffrey Mawdsley & Ilina Singh - 2023 - AJOB Empirical Bioethics 14 (1):55-64.
    Background Over the last decades, the neurosciences, behavioral sciences, and the social sciences have all seen a rapid development of innovative research methods. The field of bioethics, however, has trailed behind in methodological innovation. Despite the so-called “empirical turn” in bioethics, research methodology for project development, data collection and analysis, and dissemination has remained largely restricted to surveys, interviews, and research papers. We have previously argued for a “Design Bioethics” approach to empirical bioethics methodology, which develops purpose-built methods for investigation (...)
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  45.  25
    Developing and Testing a Checklist to Enhance Quality in Clinical Ethics Consultation.Martin L. Smith, Ruchi Sanghani, Anne Lederman Flamm, Margot M. Eves, Susannah L. Rose & Lauren Sydney Flicker - 2014 - Journal of Clinical Ethics 25 (4):281-290.
    Checklists have been used to improve quality in many industries, including healthcare. The use of checklists, however, has not been extensively evaluated in clinical ethics consultation. This article seeks to fill this gap by exploring the efficacy of using a checklist in ethics consultation, as tested by an empirical investigation of the use of the checklist at a large academic medical system (Cleveland Clinic). The specific aims of this project are as follows: (1) to improve the quality of ethics consultations (...)
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  46.  45
    Testing hypotheses in macroevolution.Lindell Bromham - 2016 - Studies in History and Philosophy of Science Part A 55:47-59.
  47.  90
    Testing the Motivational Strength of Positive and Negative Duty Arguments Regarding Global Poverty.Luke Buckland, Matthew Lindauer, David Rodríguez-Arias & Carissa Véliz - 2022 - Review of Philosophy and Psychology 13 (3):699-717.
    Two main types of philosophical arguments have been given in support of the claim that the citizens of affluent societies have stringent moral duties to aid the global poor: “positive duty” arguments based on the notion of beneficence and “negative duty” arguments based on noninterference. Peter Singer’s positive duty argument (Singer 1972) and Thomas Pogge’s negative duty argument (Pogge 2002) are among the most prominent examples. Philosophers have made speculative claims about the relative effectiveness of these arguments in promoting attitudes (...)
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  48.  57
    Prenatal Testing and Disability Rights.Walter M. Robinson, Erik Parens & Adrienne Asch - 2002 - Hastings Center Report 32 (2):45.
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  49.  16
    Patient Perceptions on the Advancement of Noninvasive Prenatal Testing for Sickle Cell Disease among Black Women in the United States.Shameka P. Thomas, Faith E. Fletcher, Rachele Willard, Tiara Monet Ranson & Vence L. Bonham - 2024 - AJOB Empirical Bioethics 15 (2):154-163.
    Background Noninvasive prenatal testing (NIPT) designed to screen for fetal genetic conditions, is increasingly being implemented as a part of routine prenatal care screening in the United States (US). However, these advances in reproductive genetic technology necessitate empirical research on the ethical and social implications of NIPT among populations underrepresented in genetic research, particularly Black women with sickle cell disease (SCD).Methods Forty (N = 40) semi-structured interviews were conducted virtually with Black women in the US (19 participants with SCD; (...)
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  50.  35
    Testing theories of plural meanings.Lyn Tieu, Cory Bill, Jacopo Romoli & Stephen Crain - 2020 - Cognition 205 (C):104307.
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