Gene expression network is also a type of complex network. It is challenging to analyze the gene expression network through relevant knowledge and algorithms of a complex network. In this paper, the existing characteristics of genes are analyzed from various indexes of the gene expression network to analyze key genes and TOP genes. Firstly, gene chip data are screened, gene data with obvious characteristics are selected, and relevant clustering characteristics are analyzed. Then, the complex gene network structure is established, and (...) gene networks with different threshold shapes and different sizes are selected. Finally, the relevant indexes and PR values after the PageRank algorithm are analyzed for complex networks under different thresholds, thus establishing the TOP gene and PR sequence. (shrink)

E-commerce conceivable future trade, consumption, and service is a new digital employer mode. Therefore, in order to decorate the customary natural environment of operation, it is quintessential to get rid of the preferred desktop in the true field, create a social logistics and transportation administration computing device with commodity agents and distributors as the key features, and mix freight logistics, business enterprise approach waft and data waft advertising and marketing, and advertising and marketing organically. The notion of e-commerce logistics looks (...) alongside the enchantment vogue of neighborhood technological knowledge and social demand. It is an integral part of ending e-commerce authentic economic value. All kinds of cell networks clear up the problem of data flow communication; in the technological know-how of telephone network, digital cost solves the bother of capital flow; at present, logistics is however a long-standing problem of e-commerce. Logistics has grown to be the last and entirely bottleneck of e-commerce. If logistics cannot adapt to the enchantment of e-commerce, it may also additionally lead to the slow enchantment of e-commerce. The purpose of this paper is to supply an Internet of things e-commerce logistics cloud provider platform based totally absolutely on cell communication, which can be combined with e-commerce and beautify the transport tempo of e-commerce. This paper moreover optimizes the e-commerce logistics system, so that it can combine with e-commerce to increase out the distribution of goods, the distribution tempo of e-commerce is doubled, and e-commerce can in a similar fashion develop rapidly. (shrink)

This study investigates the phonological development of Mandarin voiceless affricates produced by Mandarin-speaking children. Thirty-six monolingual Mandarin-speaking children and twelve adults participated in a speech production task. Auditory-based transcription analysis and acoustic analysis were utilized to quantify the relative order of affricate acquisition. Both methods yielded earlier acquisition of alveopalatal affricates at age three than retroflex and alveolar affricates, whereas they differed in the acquisition order of retroflex and alveolar affricates. The former revealed that both retroflex and alveolar affricates were (...) acquired at age five, regardless of aspiration, while the latter yielded earlier acquisition of retroflex than alveolar affricates. Possible reasons for the discrepancy are discussed in relation to the different nature of the two methods. Overall, the observed acquisition order of Mandarin voiceless affricates suggests that child speech development is a complex process, and is influenced by various factors including oromotor maturation and language-specific phoneme frequencies in the ambient language. (shrink)

Reading comprehension is never considered a simple task in linguists’ views as it requires a full set of linguistic knowledge, such as word decoding, understanding syntactic and morphological structures, and deriving proper meanings from these structures in a given context. Bearing the simple view of reading, the primary goal of this study is to explore whether the split presentation of Chinese splittable compounds influences the recognition of the compounds in second language (L2) Chinese reading comprehension, and how the reading skills, (...) i.e., word decoding and linguistic comprehension, cooperate to complete this reading comprehension task. Splittable compounds (SCs) in Chinese are typically verbs composed of two constituents with limited separability. The separable property of SCs and their vague morpho-syntactic status are supposed to cause difficulties for L2 Chinese learners in recognizing the compounds. Especially for those whose native language manifests lexical integrity, the split presentation of the compounds may invite the L2 Chinese readers to process them with a mechanism different from that for their non-split forms. To the best of our knowledge, the efforts on investigating this issue are insufficient. In this study, 27 Spanish speaking L2 Chinese learners were invited to complete tasks including reading and interpreting 6 selected SCs in the split and non-split forms, rating their familiarities with each SC and reporting the syntactic category of the SCs based on their existing linguistic knowledge. The results, showed that the split presentation of SCs did cause challenges for L2 Chinese learners in recognizing the compounds in the reading process, regardless of their Chinese proficiencies. The L2 Chinese participants performed significantly worse in recognizing split SCs in salient Verb-Object structures than recognizing those in unsalient Verb-Object structures. These findings underscore the importance of linguistic comprehension in L2 Chinese in-text word reading comprehension and suggest words as the basic processing units. (shrink)

The present study (N= 109) set out to examine the role of cross-linguistic differences as a source of potential difficulty in the acceptance and online interpretation of the English singulartheyby Chinese English as a Foreign Language (EFL) learners across two levels of second-language proficiency. Experiment 1 operationalized performance through an untimed acceptability judgment test and Experiment 2 through a self-paced reading task. Statistical analyses yielded an asymmetric pattern of results. Experiment 1 indicated that unlike native English speakers who generally accepted (...) the singulartheywith all antecedent types, two Chinese EFL groups consisting of English majors (higher level) and non-English majors (lower level) both rated it as the least acceptable pronoun regardless of their proficiency level. In contrast, Experiment 2 demonstrated that like native English speakers, both Chinese EFL groups were not disrupted in their reading by the use of the singulartheymost of the time, although its online interpretation was modulated by L2 proficiency levels of the participants. While the English majors were not affected by the use of the singularthey, the non-English majors spent a significantly longer time reading the latter region of the sentences where the singulartheywas used. In short, the results of the two experiments seem to indicate that under no time constraint, L2 speakers showed a heightened degree of grammar sensitivity, whereas when there was a time constraint, their grammatical sensitivity was reduced by a greater need to focus on meaning. The difficulty for Chinese EFL learners to acquire the singulartheymay be located at the restructuring of their existing knowledge of the plural feature ofthey[−PLURAL] in their mental lexicon and the adaptation to the sociocultural norms of the target language. The pedagogical implications of the findings are discussed. (shrink)

Aiming at the problem of insufficient health monitoring of the elderly in the existing home care system, this paper designs a health information analysis and early warning system based on the Internet of Things technology, which can monitor the physiological data of the elderly in real time. It also can be based on the elderly real-time monitoring data, physical examination data, and other types of health data, which can be used to predict diseases, so as to achieve “early detection and (...) early treatment” of diseases. First, analyse and design the architecture and content of the home care monitoring system based on the Internet of Things. Secondly, based on the collected heart rate, blood pressure, and three-axis acceleration information of the elderly, it is analysed to determine whether the elderly are in danger of falling, and the designed system is used for early warning. Finally, this paper analyses the prediction algorithm theory of the disease prediction module in the health monitoring software of the home care system. In order to improve the accuracy of prediction, the DS evidence theory is used to optimize the traditional BP neural network algorithm and conduct experimental tests. The test results show that the health information analysis and early warning software of the home care system meet actual needs and achieve the expected goals. (shrink)

How to improve the safety behaviors of construction workers has dogged the realm of construction project management. Previous studies mainly focused on the individual and/or organizational factors shaping safety behaviors, while there is a dearth of research focusing on the effect of individual-organizational nexus. Thus, this study employs social network analysis and multivariable regression analyses to explore the relationship between the characteristics of social networks of construction workers and their safety behaviors, considering the mediating role of safety communication. The primary (...) data were collected from ten Chinese construction projects. The results include the following three aspects. First, degree centrality, closeness centrality, and betweenness centrality all exert significant positive effects on safety participation. Closeness centrality yields a positive effect on safety compliance in formal networks. Degree centrality has a positive effect on both safety compliance and safety participation, whereas the other two centrality characteristics exhibit no significant effect in informal networks. Second, in formal networks, safety communication plays a partial mediation role between closeness centrality and safety compliance and a full mediation role between degree and closeness centralities and safety participation. Third, in informal networks, safety communication plays a full mediation role between degree centrality and safety compliance and a partial mediation role between degree centrality and safety participation. This study provides new insights for construction project management in achieving improved safety performance via shaping the social network characteristics. (shrink)

Despite research supporting the efficacy of family therapy for adolescent depression, little research has been done to clarify the therapeutic variables that Chinese families with depressed adolescents consider helpful in family therapy. This study explored Chinese depressed adolescents’ and their parents’ perceptions of the factors promoting improvement in family therapy. Twelve Chinese families with one adolescent child fulfilling the criteria for major depressive disorder were recruited. A total of 134 family therapy sessions were conducted by 4 therapists. After therapy, semi-structured (...) interviews about the clients’ perceptions of the helpful and effective aspects of therapy were conducted. Thematic analysis was used to analyze the transcribed dialogues. Five overarching themes emerged: factors supporting therapeutic alliance formation, the therapist’s systemic attitude, systemic therapy direction, effective systemic therapy techniques and strategies for dealing with current issues. A trustworthy therapy alliance with a competent and supportive therapist helped depressed adolescents improve by facilitating the expression of their emotions; exploring family interactions, beliefs and emotion flows related to their symptoms; promoting their self-development; and activating their resources. The families valued the respectfulness of the therapists and their collaborative and nonauthoritative approach. Adolescents’ academic difficulties and crises received special attention. The possible clinical implementations of our findings in the design of family therapy strategies for depressed Chinese adolescents are discussed. (shrink)

China set the goal of expanding early childhood education in 2018, by encouraging the development of public interest kindergartens to provide high-quality, low-cost preschool services to the general public. This is in response to the challenges of accessibility, affordability, and accountability besetting China’s current ECE system. However, the transition toward PIK has been slow due to various complex problems, including the lackluster willingness of ECE providers to become PIK. To better understand the challenges leading to low participation, this study explores (...) the external pressures affecting ECE providers and evaluates the external factors that influence their level of social responsibility. A stratified-random sampling questionnaire survey solicited responses from 832 ECE personnel representing 261 kindergartens from across China. Our findings suggest that institutional pressure has a positive effect on social responsibility and inclusive participation. We also found that institution visibility positively regulates the relationship between institutional pressure and social responsibility. At the same time, the level of environmental perception positively governs the relationship between social responsibility and participation willingness. Kindergartens should have certain social values, including assuming certain behaviors and participating in social activities in the spirit of social service and ensure multiple subjects’ synergetic governance. (shrink)

As an unusual event, fasting can induce strong physiological and psychological reactions, but there is still no clear understanding of how previous fasting experiences affect people’s responses to current fasting. This study aimed to investigate the influence of previous fasting experiences on participants’ basic physiological and psychological responses in a fasting experiment conducted under intensive medical monitoring. For a 22-day experiment divided into four phases, a total of 13 persons participated; the participants were divided into a group with prior fasting (...) experience and a group without prior fasting experience. The results indicate no group differences in physiological responses ; however, differences in psychological states were observed, with the Newbie group showing more negative psychological states overall throughout the experiment. Hence, previous fasting experience may be a buffer against negative feelings during current fasting. For this reason, it is important to consider fasting experiences as a vital factor in future research. (shrink)

For scholars, practitioners, and legislators concerned about sexual minority adolescents, one of the main goals is to create more positive and inclusive learning environments for this minority group. Numerous factors, such as repeated patterns of homophobic bullying by classmates and others in school, have been a significant barrier to achieving this goal. In addition, lesbian, gay, bisexual, transgender, and queer adolescents encounter substantial inequality across a broad spectrum of wellbeing and education consequences. Compared with their heterosexual counterparts, LGBTQ adolescents experience (...) more anxiety, depression, suicidal thoughts, antisocial behavior, poorer academic performance, less school attachment and protection, and a weaker desire to finish their studies. Such discrepancies based on gender and sexuality were linked to more maltreatment encountered by LGBTQ adolescents. It is crucial to recognize the backgrounds and expectations of LGBTQ adolescents to offer them the best resources. To overcome the inequality and obstacles faced by these LGBTQ adolescents, it is essential to examine tools and techniques that can be utilized. This study examined the literature that explains why society fails to provide enough support to LGBTQ students. Specifically, mechanisms explaining how LGBTQ adolescents interact with others in the learning environment and how such discrepancies arise will be examined. Following that, violence and prejudice, which are fundamental causes of psychological problems among LGBTQ adolescents, will be explored. This review paper thus provides supportive strategies for schools to develop more inclusive learning environments for LGBTQ adolescents. (shrink)

Chinese culture is a lively and active organism. If we are to get to the real image of Chinese culture, we should take as a starting point the first passage of the Chung-yung [Doctrine of the Mean], which expounds its basic principles: "That which Heaven has decreed is called Nature, to follow that Nature is called tao [way] and to cultivate the tao is called instruction." This passage uses three phrases and one breath; these three phrases have a unified nature (...) which cannot be separated and which constitute one long sentence. Because of this, the words as a whole lead people to think of a richly vital and great tree which has the will of Heaven as its roots, human nature as its shoots, the tao as its trunk, and cultural instruction as its branches, leaves, and blossoms. As for the fruit, in terms of the individual, it is the achievement of a completely beautiful character, and in terms of the masses of the people, it is the ordering of the country and the pacification of the realm, the progression from the era of peace under the ancient kings to the age of the Grand Unity [ta-t'ung]. (shrink)

Scientific articles have been traditionally written from single points of view. In contrast, new knowledge is derived strictly from a dialectical process, through interbreeding of partially disparate perspectives. Dialogues, therefore, present a more veritable form for representing the process behind knowledge creation. They are also less prone to dogmatically disseminate ideas than monologues, alongside raising awareness of the necessity for discussion and challenging of differing points of view, through which knowledge evolves. Here we celebrate 250 years since the discovery of (...) the chemical identity of the inorganic component of bone in 1769 by Johan Gottlieb Gahn through one such imaginary dialogue between two seasoned researchers and aficionados of this material. We provide the statistics on ups and downs in the popularity of this material throughout the history and also discuss important achievements and challenges associated with it. The shadow of Samuel Beckett’s Waiting for Godot is cast over the dialogue, acting as its frequent reference point and the guide. With this dialogue presented in the format of a play, we provide hope that conversational or dramaturgical compositions of scientific articles—albeit virtually prohibited from the scientific literature of the day—may become more pervasive in the future. (shrink)

Bromodomain‐containing 4 (BRD4), a member of Bromo and Extra‐Terminal (BET) family, recognizes acetylated histones and is of importance in transcription, replication, and DNA repair. It also binds non‐histone proteins, DNA and RNA, contributing to development, tissue growth, and various physiological processes. Additionally, BRD4 has been implicated in driving diverse diseases, ranging from cancer, viral infection, inflammation to neurological disorders. Inhibiting its functions with BET inhibitors (BETis) suppresses the progression of several types of cancer, creating an impetus for translating these chemicals (...) to the clinic. The diverse roles of BRD4 are largely dependent on its interaction partners in different contexts. In this review we discuss the molecular mechanisms of BRD4 with its interacting partners in physiology and pathology. Current development of BETis is also summarized. Further understanding the functions of BRD4 and its partners will facilitate resolving the liabilities of present BETis and accelerate their clinical translation. (shrink)

In this study, for COVID-19, we divide people into four categories: susceptible S t, closely contacted C t, infective I t, and removed R t according to the current epidemic situation and then investigate two models: the SCIR models with immigration and without immigration. For the former, Model 1, we obtain the condition for global stability of its disease-free equilibrium. For the latter, Model 2, we establish the local asymptotic stability of its endemic equilibrium by constructing Lyapunov function. Afterwards, by (...) the bifurcation theory, we qualitatively analyze the properties of its Hopf bifurcations of the latter. Finally, numerical simulations are given to illustrate the obtained results of two models. The results imply the importance of finding closely contacted and overseas imports on epidemic control. It indicates that not only the incubation delay τ is crucial for the containment of the COVID-19 but also the scientific and rigorous containment measures are the key factors of the success of the containment. (shrink)

In the target article arguments for “a moral duty to disclose all adverse clinical trial results to participants” (Liao et al. 2009, 24), the authors have made an important contribution to respecti...

What is the criterion of truth? This is a question that was resolved long ago by the revolutionary teachers of the proletariat. But as a result of damage done by the "Gang of Four" and a mass of distorted propaganda in the media under their control, it has become muddled beyond compare in recent years. In order to deepen the criticism of the "Gang of Four" and eradicate the remnants of their poison and influence, it is very important to clear (...) this up and sort it out. (shrink)

This paper uses WIOD data to calculate and analyze the dominant comparative advantage of Chinese manufacturing global value chain based on the WWZ method and empirically studies the influence of digitization on the competitiveness of manufacturing GVC. The main findings are as follows: The competitiveness of Chinese manufacturing GVC has been improved as a whole. The GVC competitiveness of different types of industries is quite different: GVC in middle- and low-knowledge-intensive industries have the highest competitiveness, while those with middle- and (...) high-knowledge-intensive industries have the lowest competitiveness and apparent shortboard industries. Digitization is conducive for enhancing the competitiveness of manufacturing GVC. In terms of industries, digitization has a significant positive effect on the GVC competitiveness of middle and high-knowledge-intensive industries but not on low knowledge ones. As for the sources of digital input, the positive effect is more outstanding. Also, it is more remarkable when it comes to the software and information technology service industry. As for the mechanism of action, labor productivity is an effective way to improve the manufacturing GVC competitiveness digitally. Finally, after a robustness test, the positive effect of the digital input remains robust. (shrink)

In Whitehead’s theory of “events”, the primary focus is on the critical assessment of abstraction. Modern science’s heavy reliance on abstraction has resulted in what Whitehead calls “the fallacy of misplaced concreteness”, where the abstract is mistaken for the actual. To address this issue, Whitehead replaces the traditional category of abstraction with eternal objects and defines the abstractive hierarchy. He aims to clarify the metaphysical status of abstraction and concreteness while dissolving their binary opposition. It is important to note that (...) there are two possible approaches for interpreting an abstractive hierarchy. The differences between these approaches stem from the question of whether abstraction and complexity should be considered identical concepts. Based on their respective understandings, the abstractive hierarchy will exhibit different structural features, as well as varying positions for the concepts of abstraction and eternal objects within Whitehead’s metaphysical thought. (shrink)

Cet article s’intéresse aux familles chinoises vivant à distance dans le contexte de l’immigration intellectuelle des jeunes chinois. Les communications intrafamiliales s’appuient sur Wechat, qui permet non seulement de garantir les échanges quotidiens, mais aussi de gérer la présence parentale en ligne. Partant d’une approche sociologique, cet article traite des stratégies de mise en scène adoptées par les jeunes chinois étudiant en France. Un travail empirique a été mené afin d’analyser comment ils se comportent devant leurs parents restés en Chine (...) en répondant aux attentes sur les études, sur le projet d’avenir, sur l’argent et sur la vie amoureuse. L’article vise à saisir la manière dont les jeunes chinois réinterprètent les relations familiales. (shrink)

AimOur study aimed to investigate the effect of social responsibility on the subjective well-being of volunteers for COVID-19 and to examine the mediating role of job involvement in this relationship.BackgroundNowadays, more and more people join volunteer service activities. As we all know, volunteer work contributes to society without any return. Volunteers often have a strong sense of social responsibility and reap subjective well-being in their dedication. Although research shows that social responsibility will drive them to participate in volunteer work actively, (...) it is less clear whether job involvement will impact their subjective well-being.MethodsThe data were collected in the precaution zone in Shanghai, China, from April to May 2022. A sample of 302 volunteers for COVID-19 completed the social responsibility scale, subjective well-being scale and job involvement scale in the form of an electronic questionnaire on their mobile phones. A structural equation model was adopted to verify the research hypotheses.ResultsSocial responsibility was significantly and positively related to volunteers’ subjective well-being and job involvement. Job involvement fully mediates the relationship between volunteers’ social responsibility and subjective well-being.ConclusionSocial responsibility is critical to predicting volunteers’ subjective well-being. Job involvement plays an intervening mechanism in explaining how social responsibility promotes volunteers’ subjective well-being. (shrink)

Children posit unobserved causes when events appear to occur spontaneously. What about when events appear to occur probabilistically? Here toddlers saw arbitrary causal relationships in a fixed, alternating order. The relationships were then changed in one of two ways. In the Deterministic condition, the event order changed ; in the Probabilistic condition, the causal relationships changed. As intended, toddlers looked equally long at both changes. We then introduced a previously unseen candidate cause. Toddlers looked longer at the appearance of a (...) hand and novel agent in the Deterministic than the Probabilistic conditions, but looked equally long at novel non-agents, suggesting that by 2 years of age, toddlers connect probabilistic events with unobserved agents. (shrink)

本书简要地阐明了文学本文的创造过程,文学作品的构成及其实现过程,文学的审美价值系统及其实现过程,文学的历史发展过程。.

Nonintrusive load monitoring in smart microgrids aims to obtain the energy consumption of individual appliances from the aggregated energy data, which is generally confronted with the error identification of the load type for energy disaggregation in microgrid energy management system. This paper proposes a classification strategy for the nonintrusive load identification scheme based on the bilateral long-term and short-term memory network algorithm. The sliding window algorithm is used to extract the detected load event features and obtain the load features of (...) data samples. In order to accurately identify these load features, the steady state information is combined as the input of the Bi-LSTM model during training. Comprising long-term and short-term memory network and recurrent neural network, Bi-LSTM has the advantages of stronger recognition ability. Finally, precision, recall, accuracy, and F1 values are used as the evaluation method for nonintrusive load identification. The experimental results show the accuracy of the Bi-LSTM identification method for load start and stop state feature matching; moreover, the method can identify relatively low-power and multistate appliances. (shrink)

There seems to have been a time at which sentient beings have not escaped from the dungeon of individuality. In the East, liberation was elaborated into a fine art, but it may be doubted whether more people may not have made their escape from solitary confinement outside the organized religions than by means of them. In the West reintegration was sporadic but in recent years it has become a widespread preoccupation. Unfortunately its technical dependence on oriental literature- sometimes translated by (...) scholars whose knowledge of the language was greater than their understanding of the subject-has proved a barrier which rendered full comprehension laborious and exceedingly long. There it appears to be essential that such teaching as may be transmissible shall be given in modern idiom and in accordance with out own processes of thought. Enlightenment and the Extinction of 'Me' It: On Realizing the Mind This Phenomenal Absence Potential Reality Potential Being Seeking the Seeker. (shrink)

本書是對華嚴宗哲學的現代詮釋。嚴華宗作為漢傳佛教最后成立的宗派之一，其哲學思想是印度大乘中觀、唯識和如來藏教佛教思想的集大成者，代表着大乘佛教思想的一個巔峰。對華嚴哲學的現代詮釋，正適合於為佛教思想研 究提供一種整體性的佛教本位的詮釋。.

ObjectiveWhen regaining consciousness, patients who emerge from a minimally conscious state (EMCS) present with different levels of functional disability, which pose great challenges for treatment. This study investigated the frontoparietal activity in EMCS patients and its effects on functional disability.Materials and methodsIn this preliminary study, 12 EMCS patients and 12 healthy controls were recruited. We recorded a resting-state scalp electroencephalogram (EEG) for at least 5 min for each participant. Each patient was assessed using the disability rating scale (DRS) to determine (...) the level of functional disability. We analyzed the EEG power spectral density and sensor-level functional connectivity in relation to the patient’s functional disability.ResultsIn the frontoparietal region, EMCS patients demonstrated lower relative beta power (P < 0.01) and higher weighted phase lag index (wPLI) values in the theta (P < 0.01) and gamma (P < 0.01) bands than healthy controls. The frontoparietal theta wPLI values of EMCS patients were positively correlated with the DRS scores (rs = 0.629, P = 0.029). At the whole-brain level, EMCS patients only had higher wPLI values in the theta band (P < 0.01) than healthy controls. The whole-brain theta wPLI values of EMCS patients were also positively correlated with the DRS scores (rs = 0.650, P = 0.022). No significant difference in the power and connectivity between the frontoparietal region and the whole brain in EMCS patients was observed.ConclusionEMCS patients still experience neural dysfunction, especially in the frontoparietal region. However, the theta connectivity in the frontoparietal region did not increase specifically. At the level of the whole brain, the same shift could also be seen. Theta functional connectivity in the whole brain may underlie different levels of functional disability. (shrink)