Tumors, abscesses, cysts, scars, fractures are familiar types of what we shall call pathological continuant entities. The instances of such types exist always in or on anatomical structures, which thereby become transformed into pathological anatomical structures of corresponding types: a fractured tibia, a blistered thumb, a carcinomatous colon. In previous work on biomedical ontologies we showed how the provision of formal definitions for relations such as is_a, part_of and transformation_of can facilitate the integration of such ontologies in ways which have (...) the potential to support new kinds of automated reasoning. We here extend this approach to the treatment of pathologies, focusing especially on those pathological continuant entities which arise when organs become affected by carcinomas. (shrink)

To enhance the treatment of relations in biomedical ontologies we advance a methodology for providing consistent and unambiguous formal definitions of the relational expressions used in such ontologies in a way designed to assist developers and users in avoiding errors in coding and annotation. The resulting Relation Ontology can promote interoperability of ontologies and support new types of automated reasoning about the spatial and temporal dimensions of biological and medical phenomena.

The value of any kind of data is greatly enhanced when it exists in a form that allows it to be integrated with other data. One approach to integration is through the annotation of multiple bodies of data using common controlled vocabularies or ‘ontologies’. Unfortunately, the very success of this approach has led to a proliferation of ontologies which itself creates obstacles to integration. The Open Biomedical Ontologies (OBO) consortium has set in train a strategy to overcome this problem. Existing (...) OBO ontologies, including the Gene Ontology, are undergoing a process of coordinated reform and new ontologies being created on the basis of an evolving set of shared principles governing ontology development. The result is an expanding family of ontologies designed to be interoperable, logically well-formed, and to incorporate accurate representations of biological reality. We describe the OBO Foundry initiative, and provide guidelines for those who might wish to become involved. (shrink)

Financial economics, and the calculations of time and uncertainty derived from it, are playing an increasingly important role in non-finance areas, such as monetary and environmental economics. In this 2001 book, Professors Le Roy and Werner supply a rigorous yet accessible graduate-level introduction to this subfield of microeconomic theory and general equilibrium theory. Since students often find the link between financial economics and equilibrium theory hard to grasp, they devote less attention to purely financial topics such as calculation of (...) derivatives, while aiming to make the connection explicit and clear in each stage of the exposition. Emphasis is placed on detailed study of two-date models, because almost all of the key ideas in financial economics can be developed in the two-date setting. In addition to rigorous analysis, substantial sections of discussion and examples are included to make the ideas readily understandable. (shrink)

All of metaethical positions today can be replaced by a universal architecture of moral philosophy, all but one: moral realism. Here, I use the term “metaethics” to refer to any theory of ethics concerning the groundwork of ethics, on the one hand, and the inquiry of the use of philosophical words, concepts or methods on the other. In this article, I will present my hypothesis that in moral philosophy, we do not need any specialized metaethics at all. Metaethics as a (...) discipline of philosophy is only required by the work of moral realists, who try to show us a realm of values and norms that exist (per se) naturally, non-naturally or supernaturally. How can they know? The effort of metaethical realists cannot be proven either in ontology or in the philosophy of language or in cognitive science or in any meta-science that works en plus to ethics, because even in every additional discipline, we have to accept the presupposition of a validity of judgments. So, let us try it the other way around; we have to find a way to found ethics by following its structures, and that means, based on David Velleman’s concepts: a) We have to search for a ubiquitous point of ethical theory in its foundation – here, no kind of value or norm can be found that is not based on a universal formal structure of normativity. b) We have to start an empirical inquiry to collect norms and values in actual use. MFT, moral psychology and moral sociology are in charge here. The combination of such an abstract groundwork with mere empirical study has to be legitimized again. Hence, I am going to try to sum up the main ideas of such a project to show the relevance of a new architecture of moral philosophy today. There is a line of reasoning that addresses the possibility of a transcendental critique in practical philosophy; therefore, it has to look into the different notions of “intuition” in moral methods like it was used by Sidgwick (Rashdall, Green, Ross, Brentano, McTaggart) and Moore on the one hand and Brentano and Bergson on the other. In my view, there is a way to combine these perspectives using the two-level-model of Hare, Singer, Greene, where “intuition” is used to categorize habits and customs of the common sense morality in general while a critical reflection uses act-utilitarian calculus to provide a universal decision – in the sense of “concrete reason” – for any possible actor in a singular situation (Hegel, Peirce, Bloch etc.). The change between these levels may be explained by means of a pragmatistic kind of continuum of research with an ideal summum bonum in the long run and a concept of common sense morality as can be found in every group or society. (shrink)

INTRODUCTION WERNER ABRAHAM, LACI MARÁCZ, SJAAK DE MEY & WIM SCHERPENISSE University of Groningen The Groningen Conference on Topic, ...

MODERN ARISTOTELIAN SCHOLARSHIP is heavily indebted to the German scholars of the nineteenth century who produced the Berlin Academy editions of Aristotle's corpus and of his Greek commentators. The foundations for this massive project were laid around the middle of the century by people like Schwegler, who edited and commented on Aristotle's Metaphysics. Yet, while acknowledging our debt to such exemplary scholarship, I want to cast doubt on one of his proposed emendations to Metaphysics 6.1, which influenced later editors like (...) W. D. Ross and Werner Jaeger. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Peter Singer and Christian Ethics: Beyond Polarization by Charles E. CamosyWerner WolbertPeter Singer and Christian Ethics: Beyond Polarization CHARLES E. CAMOSY Cambridge: Cambridge University Press, 2012. 278 pp. $29.99Peter Singer’s “Copernican revolution” against a sanctity of life ethic may be regarded, from a Roman Catholic viewpoint, as an expression of the “culture of death” denounced by John Paul II. One must keep in mind, however, that “we know (...) that historically there have been times where those participating in discussions about ethics disagree deeply about theory, but nevertheless come to important and even broad agreement about applied or practical ethics” (179). The aim of Camosy’s book is to sketch the various areas of agreement and disagreement between Peter Singer and Catholic moral theology as well as the possibilities of working together.There are issues even about the subject of abortion on which Singer and the Church agree: that moral relativism is wrong; that it is seriously wrong to kill a person; that the right to privacy (see Roe vs. Wade) does not apply to acts harming others; and that the right to abortion is not a constitutional matter (chapter 1). Both positions see a connection between abortion and infanticide, but both draw different conclusions. The disagreements between them are about who is to count as a person, which Camosy comments on in the rest of chapter 1 (27–37). In the area of euthanasia, the Church and Singer share some skepticism about brain death (chapter 2). Camosy discusses the church’s position on one’s moral status at the end of life and the Roman Catholic understandings of ordinary and extraordinary means, acts, and omissions. Commenting on public policy in that field, Camosy gives some useful and convincing illustrations of the slippery slope effect in different countries that have legalized active euthanasia or assisted suicide (68–81).With regard to problems of killing, however, Helga Kuhse’s The Sanctity of Life Doctrine in Medicine (Oxford University Press, 1987) should perhaps have been considered. On the subject of acting and refraining, I would recommend Dieter Birnbacher’s Tun und unterlassen (Reclam 1995).Commenting on Singer’s championing of the moral status of nonhuman animals, Camosy points to elements in the Christian tradition that may support Singer’s issue of animal liberation (chapter 3). I wonder why the discussion concentrates on domestic animals and the problems of eating meat or [End Page 225] vegetarianism but omits problems of environmental ethics (e.g., ecological balance). Would the aim of avoiding animal harm include saving animals from predators? And if some animals are to be regarded as persons, we may get in trouble with our basic conviction of the equality (of the dignity) of human beings—as the debate on the margins of human life shows.Duties to the poor are not in dispute except for “partial preferences” (166) for members of our family, kinship, or country (chapter 4). Speaking of “partiality” in this context is, however, a bit misleading. Since no one can care for all people, preferences of an ordo caritatis (order of love) are a necessary part of a system of coordination from which—ideally—all humans can benefit. (Recall Augustine in De doctrina Christiana, 1.28–29: “The interests of society, however, and its common bonds will be best conserved if kindness be shown to each individual in proportion to the closeness of his relationship.”) Chapter 5, which compares Singer’s ethical theory with Catholic moral theology, would need more discussion (e.g., on double effect, object, and act), which I cannot cover within the limits of this review. Overall, Camosy’s book makes a valuable contribution to the dialogue between Christian and secular ethics.Werner WolbertUniversity of SalzburgCopyright © 2014 Society of Christian Ethics... (shrink)

Key ideas discussed in this guide include: art and aesthetics fun and free time nature and reason things, thoughts and being right This Routledge Critical ...

(2000). The Potentiality Argument in the Debate relating to the Beginning of Personhood. Human Reproduction & Genetic Ethics: Vol. 6, No. 2, pp. 19-26.

A translation of Werner Hamacher’s essay “Andere Schmerzen,” which he was unable to complete before his death on July 7, 2017. The essay analyzes the connection between pain and language in the work of Pindar, Sophocles, Cicero, Seneca, Kant, Hegel, and Valéry.

This book starts from the proposition that the field of intelligence lacks any systematic ethical review, and then develops a framework based on the notion of harm and the establishment of Just Intelligence Principles. As the professional practice of intelligence collection adapts to the changing environment of the twenty-first century, many academic experts and intelligence professionals have called for a coherent ethical framework that outlines exactly when, by what means and to what ends intelligence is justified. Recent controversies, including reports (...) of abuse at Guantanamo Bay and Abu Ghraib, allegations of extraordinary rendition programmes and the ever-increasing pervasiveness of the ‘surveillance state’, have all raised concerns regarding the role of intelligence in society. As a result, there is increased debate regarding the question of whether or not intelligence collection can be carried out ethically. _The Ethics of Intelligence_ tackles this question by creating an ethical framework specifically designed for intelligence that is capable of outlining under what circumstances, if any, different intelligence collection activities are ethically permissible. The book examines three of the main collection disciplines in the field of intelligence studies: imagery intelligence, signals intelligence and human intelligence. By applying the ethical framework established at the beginning of the book to these three important intelligence collection disciplines, it is possible to better understand the ethical framework while also demonstrating its real-life applicability. This book will be of much interest to students of intelligence studies, ethics, war and conflict studies, security studies and IR. (shrink)

Artykuł określa kategorie aspektu oraz wskazuje dwie odmiany stanowiska filozoficznego odnoszące się do tegoż pojęcia. Następnie przeprowadza ich krytykę w odniesieniu do współczesnej kognitywistyki.

Foundations of Indian Culture I - II. G. C. Pande. Motilal Banarsidass, Delhi, 2nd ed. 1990. x, 378 and vi, 284 pp. Rs. 325.

I shall elaborate more on the idea of anti-irrationalism proposed by the Polish analytic philosopher Kazimierz Ajdukiewicz, a prominent member of the Lvov-Warsaw School of philosophy and logic. In my reading, anti-irrationalism stands in opposition not only to overt irrationalism, which is made clear by the term itself, but also to all forms of rationalism that tip toward something like worship of reason. Having characterized anti-irrationalism as it originally appeared in Ajdukiewicz’s works, I shall propose a certain reformulation of it, (...) so as to capture a broader philosophical legacy in Poland, primarily, yet not exclusively the Lvov-Warsaw School. (shrink)

Uniformities describing the distinguishability of states and of observables are discussed in the context of general statistical theories and are shown to be related to distinguished subspaces of continuous observables and states, respectively. The usual formalism of quantum mechanics contains no such physical uniformity for states. Using recently developed tools of quantum harmonic analysis, a natural one-to-one correspondence between continuous subspaces of nonrelativistic quantum and classical mechanics is established, thus exhibiting a close interrelation between physical uniformities for quantum states and (...) compactifications of phase space. General properties of the completions of the quantum state space with respect to these uniformities are discussed. (shrink)