Responsible Research and Innovation provides a framework for judging the ethical qualities of innovation processes, however guidance for researchers on how to implement such practices is limited. Exploring RRI in the context of nanotechnology, this paper examines how the dispersed and interdisciplinary nature of the nanotechnology field somewhat hampers the abilities of individual researchers to control the innovation process. The ad-hoc nature of the field of nanotechnology, with its fluid boundaries and elusive membership, has thus far failed to establish a (...) strong collective agent, such as a professional organization, through which researchers could collectively steer technological development in light of social and environmental needs. In this case, individual researchers cannot innovate responsibly purely by themselves, but there is also no structural framework to ensure that responsible development of nanotechnologies takes place. We argue that, in such a case, individual researchers have a duty to collectivize. In short, researchers in situations where it is challenging for individual agents to achieve the goals of RRI are compelled to develop organizations to facilitate RRI. In this paper we establish and discuss the criteria under which individual researchers have this duty to collectivize. (shrink)

Volume 19, Issue 9, September 2019, Page 54-56.

The suggested citation for this white paper is: University of Waterloo Working Group on Bibliometrics, Winter 2016. White Paper: Measuring Research Outputs through Bibliometrics, Waterloo, Ontario: University of Waterloo.

In <em>Phys. Rev. A</em> <strong>63</strong> 022113 (2001), Brukner and Zeilinger claim that the Shannon information is not well defined as a measure of information in quantum mechanics, adducing arguments that seek to show that it is inextricably tied to classical notions of measurement. It is shown here that these arguments do not succeed: the Shannon information does not have problematic ties to classical concepts. In a further argument, Brukner and Zeilinger compare the Shannon information unfavourably to their (...) preferred information measure, I(p), with regard to the definition of a notion of `total information content'. This argument is found unconvincing and the relationship betwen measures of information and notions of `total information content' investigated. (shrink)

BackgroundPeople with upper extremity amputations report receiving insufficient information about treatment options. Furthermore, patients commonly report not knowing what questions to ask providers. A question prompt sheet, or list of questions, can support patient-centered care by empowering patients to ask questions important to them, promoting patient-provider communication, and increasing patient knowledge. This study assessed information needs among people with UE amputations about UE vascularized composite allotransplantation and developed a UE VCA-QPS.MethodsThis multi-site, cross-sectional, mixed-methods study involved in-depth and semi-structured interviews with (...) people with UE amputations to assess information needs and develop a UE VCA-QPS. Qualitative data were analyzed by thematic analysis; quantitative data were analyzed by descriptive statistics. The initial UE VCA-QPS included 130 items across 18 topics.ResultsEighty-nine people with UE amputations participated. Most were male, had a mean age of 46 years, and had a unilateral and below-elbow amputation. Participants desired information about UE VCA eligibility, evaluation process, surgery, risks, rehabilitation, and functional outcomes. After refinement, the final UE VCA-QPS included 35 items, across 9 topics. All items were written at a ≤ 6th grade reading level. Most semi-structured interview participants reported being ‘completely’ or ‘very’ likely to use a UE VCA-QPS.ConclusionPeople with UE amputations have extensive information needs about UE VCA. The UE VCA-QPS aims to address patients’ information needs and foster patient-centered care. Future research should assess whether the UE VCA-QPS facilitates patient-provider discussion and informed decision-making for UE VCA. (shrink)

Quantum Information Theory and the Foundations of Quantum Mechanics is a conceptual analysis of one of the most prominent and exciting new areas of physics, providing the first full-length philosophical treatment of quantum information theory and the questions it raises for our understanding of the quantum world. -/- Beginning from a careful, revisionary, analysis of the concepts of information in the everyday and classical information-theory settings, Christopher G. Timpson argues for an ontologically deflationary account of the nature of quantum information. (...) Against what many have supposed, quantum information can be clearly defined (it is not a primitive or vague notion) but it is not part of the material contents of the world. Timpson's account sheds light on the nature of nonlocality and information flow in the presence of entanglement and, in particular, dissolves puzzles surrounding the remarkable process of quantum teleportation. In addition it permits a clear view of what the ontological and methodological lessons provided by quantum information theory are; lessons which bear on the gripping question of what role a concept like information has to play in fundamental physics. Topics discussed include the slogan 'Information is Physical', the prospects for an informational immaterialism (the view that information rather than matter might fundamentally constitute the world), and the status of the Church-Turing hypothesis in light of quantum computation. -/- With a clear grasp of the concept of information in hand, Timpson turns his attention to the pressing question of whether advances in quantum information theory pave the way for the resolution of the traditional conceptual problems of quantum mechanics: the deep problems which loom over measurement, nonlocality and the general nature of quantum ontology. He marks out a number of common pitfalls to be avoided before analysing in detail some concrete proposals, including the radical quantum Bayesian programme of Caves, Fuchs, and Schack. One central moral which is drawn is that, for all the interest that the quantum information-inspired approaches hold, no cheap resolutions to the traditional problems of quantum mechanics are to be had. (shrink)

This paper demonstrates how John Dewey's notion of habit can help us understand gender as a constitutive structure of bodily existence. Bringing Dewey's pragmatism in conjunction with Judith Butler's concept of performativity, 1 provide an account of how rigid binary configurations of gender might be transformed at the level of both individual habit and cultural construct.

The story of the 'long Renaissance' for a new generation--from Giotto and Dante in thirteenth-century Italy, to the English literary Renaissance in the first half of the seventeenth century.

The Safe-by-Design approach in synthetic biology holds the promise of designing the building blocks of life in an organism guided by the value of safety. This paves a new way for using biotechnologies safely. However, the Safe-by-Design approach moves the bulk of the responsibility for safety to the actors in the research and development phase. Also, it assumes that safety can be defined and understood by all stakeholders in the same way. These assumptions are problematic and might actually undermine safety. (...) This research explores these assumptions through the use of a Group Decision Room. In this set up, anonymous and non-anonymous deliberation methods are used for different stakeholders to exchange views. During the session, a potential synthetic biology application is used as a case for investigation: the Food Warden, a biosensor contained in meat packaging for indicating the freshness of meat. Participants discuss what potential issues might arise, how responsibilities should be distributed in a forward-looking way, who is to blame if something would go wrong. They are also asked what safety and responsibility mean at different phases, and for different stakeholders. The results of the session are not generalizable, but provide valuable insights. Issues of safety cannot all be taken care of in the R&D phase. Also, when things go wrong, there are proximal and distal causes to consider. In addition, capacities of actors play an important role in defining their responsibilities. Last but not least, this research provides a new perspective on the role of instruction manuals in achieving safety. (shrink)

Hedgehog (Hh) signaling is a widely studied signaling pathway because of its critical roles during development and in cell homeostasis. Vertebrate canonical and non‐canonical Hh signaling are typically assumed to be distinct and occur in different cellular compartments. While research has primarily focused on the canonical form of Hh signaling and its dependency on primary cilia – microtubule‐based signaling hubs – an extensive list of crucial functions mediated by non‐canonical Hh signaling has emerged. Moreover, amounting evidence indicates that canonical and (...) non‐canonical modes of Hh signaling are interlinked, and that they can overlap spatially, and in many cases interact functionally. Here, we discuss some of the many cellular effects of non‐canonical signaling and discuss new evidence indicating inter‐relationships with canonical signaling. We discuss how Smoothened (Smo), a key component of the Hh pathway, might coordinate such diverse downstream effects. Collectively, pursuit of questions such as those proposed here will aid in elucidating the full extent of Smo function in development and advance its use as a target for cancer therapeutics. (shrink)

MAKING PUBLIC POLICY: A HOPEFUL VIEW OF AMERICAN GOVERNMENT by Steven Kelman New York: Basic Books, 1987.332 pp., $19.95.

Anglo-American embodiments of poststructuralist and French feminism often align themselves with the texts of either Michel Foucault or Luce Irigaray. lnterrogating this alleged distance between Foucault and Irigaray, I show how it reinscrihes the phallic field of concepts and categories within feminist discourses. Framing both Foucault and Irigaray as exceeding]acques Lacan's metamorphosis of G.W.F. Hegel's Concept, I suggest that engaging their styles might yield richer tools for articulating the differences within our different lives.

Responding to Silvia Stoller's comments on “Domination and Dialogue in Merleau-Ponty's Phenomenology of Perception”, I argue that while phenomenology has much to offer feminism, feminists should be wary of Merleau-Ponty's notion of projective intentionality because of the ethical solipsism that it tends to involve. I also take the opportunity to clarify the concept of hypothetical construction introduced in the earlier paper, in particular the transformative relationship that it has to pre-reflective experience.

The purpose of this paper is to elucidate, by means of concepts and theorems drawn from mathematical logic, the conditions under which the existence of a multiverse is a logical necessity in mathematical physics, and the implications of Gödel’s incompleteness theorem for theories of everything.Three conclusions are obtained in the final section: (i) the theory of the structure of our universe might be an undecidable theory, and this constitutes a potential epistemological limit for mathematical physics, but because such a theory (...) must be complete, there is no ontological barrier to the existence of a final theory of everything; (ii) in terms of mathematical logic, there are two different types of multiverse: classes of non-isomorphic but elementarily equivalent models, and classes of model which are both non-isomorphic and elementarily inequivalent; (iii) for a hypothetical theory of everything to have only one possible model, and to thereby negate the possible existence of a multiverse, that theory must be such that it admits only a finite model. (shrink)

This concluding chapter addresses the conceptual questions that arise in connection with identifying a philosophical tradition, and giving it a distinctive national label. It argues against the common identification of ‘Scottish philosophy’ with the ‘School of Common Sense’, and argues that Francis Hutcheson initiated an approach to philosophical questions that pre-dates the appeal to common sense developed by Reid. It contends that the ‘School of Common Sense’ was just one attempt to formulate a satisfactory response to David Hume. By examining (...) the work of Andrew Seth and Henry Jones, it explores the idea of a shared philosophical agenda, and argues that a common project rooted in a long-standing institutional framework is what sustained the Scottish philosophical intellectual tradition. The chapter ends by considering the factors that may be said to have brought that tradition to an end. (shrink)

Linguistic studies have shown that the traditional idea that the expansion of the Inca Empire was the driving force behind the spread of all Quechua cannot be correct. Across much of its distribution, Quechua has far greater time-depth than can be accounted for by the short-lived Inca Empire. Linguistics likewise suggests that Aymara spread not from the south into Cuzco in the late Pre-Inca period, but also from an origin to the north. Alternative explanations must be sought for the expansion (...) of these language families in the culture history of the Andes. Archaeological studies over the past two decades now provide a broad, generally agreed-upon outline of the cultural history of the Cuzco region. This chapter applies those findings to examine alternative possibilities for the driving forces that spread Quechua and Aymara, offering a clearer cross-disciplinary view of Andean prehistory. (shrink)

A mitigation bank is a large wetland or wetland complex that is developed for the sake of selling credits to private developers or government agencies to compensate for the destruction of natural wetlands. The United States Army Corps of Engineers often sets as a condition for issuing a Section 404 permit the purchase of a certain number of bank credits. Mitigation banking is now emphasized within Corps’ policy, and it has become big business within the United States. Arguments for mitigation (...) banking stress the efficiency in permitting and monitoring that banking makes possible. Proponents of banking claim that banking is ecologically beneficial to wetland plants and animals, but recent studies have shown that mitigation banking threatens biodiversity. The problem, generally, is consolidation. Underlying mitigation banking, and embedded within Corps policy, is the assumption that preservation of wetland functions must accommodate to a large extent desired levels of economic development and efficiency in the development process. (shrink)

This paper reviews the validity of National Curriculum assessment in England. It works with the concept of 'consequential validity' (Messick, 1989) which incorporates both conventional 'reliability' issues and the use to which any assessment is put. The review uses the eight stage 'threats to validity' model developed by Crooks, Kane and Cohen (1996). The complexity of National Curriculum assessment makes evaluation difficult. These assessments are used for a variety of purposes so that the 'consequential' aspects are compounded. National Curriculum assessment (...) also involves both Teacher Assessment and tests - each of which has strengths and limitations in relation to validity. The main finding is that the validity of National Curriculum assessment hinges on the balance between Teacher Assessment and testing. Between them they can meet Crooks et al.'s requirements of a valid assessment system. The current emphasis on the use of test results for school accountability and as a measure of national standards has undermined Teacher Assessment to a point at which the validity of the system is in question. (shrink)