To foster understanding in the psychopathology of patients with anorexia nervosa at the psychological and physiological level, standardized experimental studies on reliable biomarkers are needed, especially due to the lack of disorder-specific samples. To this end, the autonomic nervous system response to a psychosocial stressor was investigated in n = 19 PAN, age, and gender-matched to n = 19 healthy controls. For this purpose, heart rate and heart rate variability parameters were assessed in a cross-sectional study design under two experimental (...) conditions: rest and stress. In addition, psychological indicators of stress were assessed. An 2 × 2 × 8 ANOVA demonstrated similar HR and HRV patterns between PAN and HC at rest. Under stress, PAN demonstrated a blunted HR [condition*time*group: F = 9.326, p = 0.000, η2 = 0.206] and an attenuated HRV response. Significant effects of stress appraisal and BMI on HRV-reactivity were revealed. SA on SDNN = Condition*time*SA = F = 2.676, p = 0.033, η2 = 0.073. BMI on LF/HF-Ratio = Condition*time*BMI = F = 3.339, p = 0.019, η2 = 0.164. Psychological indices suggested higher levels of chronic and appraised stress in PAN relative to HC. Additional analyses demonstrated that ED-symptoms are highly correlated with the latter constructs, as well as with psychological burden, but not with weight. Further, it was shown that abnormalities in reactivity persisted despite normalized ANS activity. Overall, we suggested that besides weight recovery, improvement in stress appraisal could be beneficial for cardiac health. In this light, a combination of therapy and biofeedback training may improve treatment outcomes and regulate stress reactivity. (shrink)

This article explores the existential conditions for a transition towards socioeconomic degrowth through an analysis of a paradigm shift between two extreme polarities of socio-ecological positioning: the Dominant Social Paradigm (DSP) and the New Ecological Paradigm (NEP). It is suggested that the transition from one to the other – understood as the first collective step towards degrowth – requires a transformation in the way we, in western capitalist society, define ourselves in relation to nature. This identity transformation corresponds with the (...) reconnection between humans and nature that ecopsychology has been calling for since its emergence in the 1970s. However, according to recent empirical studies in existential psychology, such a transformation contains potentially disquieting aspects, since it implies recognising and accepting the idea of our own mortality. Staging a dialogue between ecopsychology and critical degrowth theories, this article argues that the necessary transition towards degrowth requires new ways of dealing with these existential fears – namely, confronting them in a ‘reflexive’ rather than ‘defensive’ way – so as to develop relationships with nature that respect the limits of the biosphere. (shrink)

Many languages grammatically mark evidentiality, i.e., the source of information. In assertions, evidentials indicate the source of information of the speaker while in questions they indicate the expected source of information of the addressee. This dissertation examines the semantics and pragmatics of evidentiality and illocutionary mood, set within formal theories of meaning and discourse. The empirical focus is the evidential system of Cheyenne (Algonquian: Montana), which is analyzed based on several years of fieldwork by the author.

What is the best model of epistemic agency for virtue epistemology? Insofar as the intellectual and moral virtues are similar, it is desirable to develop models of agency that are similar across the two realms. Unlike Aristotle, the Stoics present a model of the virtues on which the moral and intellectual virtues are unified. The Stoics’ materialism and determinism also help to explain how we can be responsible for our beliefs even when we cannot believe otherwise. In this paper I (...) show how a neo-Stoic model of epistemic agency can address common objections to treating epistemic and moral agency similarly and allow a robust explanatory role for character in determining our actions and beliefs. The picture of epistemic responsibility that flows from this model also explains why we often deserve credit for our knowledge, while demonstrating that the truth of our beliefs is not something for which we are epistemically responsible. (shrink)

This paper argues that several leading theories of subjunctive conditionals are incompatible with ordinary intuitions about what credences we ought to have in subjunctive conditionals. In short, our theory of subjunctives should intuitively display semantic humility, i.e. our semantic theory should deliver the truth conditions of sentences without pronouncing on whether those conditions actually obtain. In addition to describing intuitions about subjunctive conditionals, I argue that we can derive these ordinary intuitions from justified premises, and I answer a possible worry (...) for my derivation by refuting a subjunctive triviality result modeled on (Lewis 1976). I conclude that the debate over the correct theory of subjunctive conditionals requires settling meta-philosophical questions about the relative value of various virtues of first-order theories of subjunctive conditionals. (shrink)

This paper presents a feminist analysis of corporate social responsibility in a male-dominated industry within a developing country context. It seeks to raise awareness of the silencing of women’s voices in CSR reports produced by mining companies in Tanzania. Tanzania is one of the poorest countries in Africa, and women are often marginalised in employment and social policy considerations. Drawing on work by Hélène Cixous, a post-structuralist/radical feminist scholar, the paper challenges the masculinity of CSR discourses that have repeatedly masked (...) the voices and concerns of ‘other’ marginalised social groups, notably women. Using interpretative ethnographic case studies, the paper provides much-needed empirical evidence to show how gender imbalances remain prevalent in the Tanzanian mining sector. This evidence draws attention to the dynamics faced by many women working in or living around mining areas in Tanzania. The paper argues that CSR, a discourse enmeshed with the patriarchal logic of the contemporary capitalist system, is entangled with tensions, class conflicts and struggles which need to be unpacked and acknowledged. The paper considers the possibility of policy reforms in order to promote gender balance in the Tanzanian mining sector and create a platform for women’s concerns to be voiced. (shrink)

Letheby’s naturalistic theory of psychedelic therapy argues that the therapeutic power of psychedelics lies in their ability to allow individuals “to discover the contingency, mutability and simulatory nature of their own sense of identity and habitual modes of attention.” The general shape of this project is persuasive; it is hard to see how the claim that successful therapy must involve changes to the self could be objected to, and Letheby sketches a consistent, if speculative, picture of psychedelic experience. But the (...) role of affect in psychedelic therapy is insufficiently explored by Letheby as a comparison to MDMA-assisted therapy indicates. This comparison further suggests that Letheby’s reliance on a particular conceptualization of ego dissolution experiences is in need of further explanation and justification. (shrink)

This book shows how such an approach fails to interrogate the precise terms, such as "Nature" or "life", that Nietzsche used in place of "being," and to ask the meaning of this substitution.

This article responds to two ethical conundrums associated with the practice of disability passing. One of these problems is the question of whether or not passing as abled is morally wrong in that it constitutes deception. The other, related difficulty arises from the tendency of the able-bodied in contemporary society to reinforce the activity of passing despite its frequent condemnation as a form of pretense or fraud. We draw upon recent scholarship on transgender and disability passing to criticize and explore (...) some alternatives to the problematic theory of personal identity that is presupposed by the claim that passing as abled always amounts to deceit. We additionally demonstrate the moral indefensibility of society’s reinforcement of disability passing by showing that it may derive, at least in part, from ablest assumptions concerning distributive justice as it relates to disabled individuals. (shrink)

Kitcher urges us to think of mathematics as an idealized science of human operations, rather than a theory describing abstract mathematical objects. I argue that Kitcher's invocation of idealization cannot save mathematical truth and avoid platonism. Nevertheless, what is left of Kitcher's view is worth holding onto. I propose that Kitcher's account should be fictionalized, making use of Walton's and Currie's make-believe theory of fiction, and argue that the resulting ideal-agent fictionalism has advantages over mathematical-object fictionalism.

As genetic and genomic research has progressed since the sequencing of the human genome, scientists have continued to struggle to understand the role of genetic and socio-cultural factors in racial and ethnic health disparities. Recognition that race and ethnicity correlate imperfectly with differences in allele frequency, environmental exposures, and significant health outcomes has made framing the relationship between genetic variation, race, ethnicity, and disease one of the most heated debates of the genome era. Because racial and ethnic identities reflect a (...) complicated mix of social and genetic factors, critics have argued that use of racial and ethnic categories as analytical variables in biomedical research lacks rigor, leads to potentially dangerous stereotyping in medical practice, and sends harmful messages of innate racial difference to the broader public.Concerns over the current lack of diversity in human genetic and genomic studies have developed in parallel to discussions of the appropriate use of racial and ethnic categories during the research process. (shrink)

Governing nursing conduct: the rise of evidence‐based practice Drawing on the Foucauldian concept of ‘governmentality’ to analyse the evidence‐based movement in nursing, we argue that it is possible to identify the governance of nursing practice and hence nurses across two distinct axes; that of the political (governance through political and economic means) and the personal (governance of the self through the cultivation of the practices required by nurses to put evidence into practice). The evaluation of nursing work through evidence‐based reviews (...) provides detailed information that may enable governments to target and instruct nurses regarding their work in the interest of preserving the health of the population as a whole. Political governance of the nursing population becomes possible through centralised discursive mechanisms, such as evidence‐based reviews that present nursing practice as an intelligible field whose elements are connected in a more or less systematic manner. The identity of the evidence‐based nurse requires the modern nurse to develop new skills and attitudes. Evidence‐based nursing is an emerging technology of government that judges nursing research and knowledge and has the capacity to direct nursing practice at both the political and personal level. (shrink)

Burge's thesis is the thesis that certain second-order self-ascriptionsare self-verifying in virtue of their self-referential form. The thesis hasrecently come under attack on the grounds that it does not yield a theory ofself-knowledge consistent with semantic externalism, and also on the groundsthat it is false. In this paper I defend Burge's thesis against both charges,in particular against the arguments of Bernecker, Gallois and Goldberg. Thealleged counterexamples they provide are merely apparent counterexamples, andthe thesis is adequate to its proper task. To (...) think otherwise is simply tomisunderstand the thesis. (shrink)

Network neuroscience provides a systems approach to the study of the brain and enables the examination of interactions measured at different temporal and spatial scales. We review current methods to quantify the structure of brain networks and compare that structure across different clinical cohorts, cognitive states, and subjects. We further introduce the emerging mathematical concept of multilayer networks and describe the advantages of this approach to model changing brain dynamics over time. We conclude by offering several concrete examples of how (...) multilayer network approaches to neuroimaging data provide novel insights into brain structure and evolving function. (shrink)

This chapter contains section titled: Benjamin Whichcote Henry More Cudworth.

In this paper I will argue that an epistemology of ignorance is a denial of relationality. Knowing is a series of practices. So is ignoring. And as practices, they are strategic. I have argued that knowing is a practice, of engagement or disengagement ("Practices of Knowing"), so is ignoring (Frye, Mills). I have argued that we need to recognize rationalities not countenanced in the dominant logic ("Resisting Rationality). And I have argued for disrupting the conceptual coercion of the dominant logic (...) as well as for uncertainty as a way of emerging from the form of life enacted through the mystification of dominant discourse ("Moving Toward Uncertainty"). In this paper I want to take up the question of relationality. From postions of power and the logic of oppression, an epistemology hides engagement and as a result erases contestation and resistance. From positions of marginalization and the logic of resistance, it resists coercive consensus. In both cases there is a denial of a certain kind of relationality. (shrink)

Identifying links between human personality and attributed robot personality is a relatively new area of human–robot interaction. In this paper we report on an exploratory study that investigates human and robot personality traits as part of a human–robot interaction trial. The trials took place in a simulated living-room scenario involving 28 participants and a human-sized robot of mechanical appearance. Participants interacted with the robot in two task scenarios relevant to a ‘robot in the home’ context. It was found that participants’ (...) evaluations of their own personality traits are related to their evaluations of the robot’s personality traits. The statistical analysis of questionnaire data yields several statistically significant results: Participants do not tend to assign their personality traits to match the robots’, For individual personality traits, participants rated themselves as having stronger personality characteristics compared to the robot, Specific significant correlations were found between participants’ and robot personality traits, and Significant group differences for participant gender, age and technological background are highlighted. The results are discussed in light of developing personalized robot companions. (shrink)

Here I set the stage for developing a Kantian account of punishment attuned to social and economic injustice and to the need for prison reform. I argue that we cannot appreciate Kant's own discussion of punishment unless we read it in light of the theory of justice of which it is a part and the fundamental commitments of that theory to freedom, autonomy and equality. As important, we cannot properly evaluate Kant's advocacy of the law of retribution unless we recognize (...) his theory of justice as an ideal theory. Once we understand both Kant's larger account of justice and its relationship to his less basic commitments, we discover grounds to accept that larger theory, but reject components like the law of retribution with their basis in empirical conclusions we may not share with Kant. We also open the way to develop an account of punishment responsive to social circumstances. (shrink)

In this article I set out to trace some of the implications of recharging the political potency of nature in more-than-human terms. This shifts attention from a biopolitical focus on the inventiveness of the life sciences and what this means in terms of the emergence of ‘cyborg’ political subjects to an onto-political focus on the inventiveness of knowledge controversies and what these mean for techno-political practices. Specifically, the article examines the onto-politics of ‘natural’ hazard events and their capacity to force (...) thought in those affected by them, and so to place new demands on research practices in terms of rendering such events affective and amenable to political interrogation. I work these arguments through the demanding experimental ethos of the philosopher Isabelle Stengers, for whom scientific practices produce reliable knowledge claims only in so far as the questions they address are at risk of being redefined by the phenomena mobilized in them, and who extends this ethos to elaborate an understanding of, even a test for, an adequate political theory and practice. I do so with reference to a recent research experiment in which I collaborated with social and natural scientists and people affected by flooding in the UK. (shrink)

I can only speculate about the echo of slavery and its impact upon how theories of race are disconnected from theories of mental illness.Haunting belongs to the structure of every hegemony.Why might psychiatry need postcolonial theories? Critical discourse on psychiatry and clinical psychology—itself quite heterogeneous across the humanities and the so-called psy disciplines—has intermittently focused on the redress of power in clinical encounters, which are often constituted by an interaction between persons in very different life circumstances and with divergent positions (...) in relation to authority and privilege, or social capital and capital itself. Postcolonial theories are relevant to this topic because they... (shrink)

The purpose of this study is to deconstruct the language used in President Trump’s Facebook posts while on the campaign trail, and the subsequent comments which reiterate and reify this rhetoric, to understand how Syrian refugees are labeled as a dangerous population unworthy of asylum. By utilizing the theoretical groundwork of Foucault, Agamben, and Mbembe, this qualitative content analysis will explore how Syrian refugees, as depicted by Facebook comments, represent a “disposable population.” We conclude that by reducing Syrian refugees to (...) a sub-human status and representing them as the dangerous and unworthy other, both President Trump who initiated this rhetoric, and those who responded in a way which legitimized his views, effectively labeled Syrian refugees as a dangerous population unworthy of asylum within the USA. (shrink)

Language and culture endow humans with access to conceptual information that far exceeds any which could be accessed by a non-human animal. Yet, it is possible that, even without language or specific experiences, non-human animals represent and infer some aspects of similarity relations between objects in the same way as humans. Here, we show that monkeys’ discrimination sensitivity when identifying images of animals is predicted by established measures of semantic similarity derived from human conceptual judgments. We used metrics from computer (...) vision and computational neuroscience to show that monkeys’ and humans’ performance cannot be explained by low-level visual similarity alone. The results demonstrate that at least some of the underlying structure of object representations in humans is shared with non-human primates, at an abstract level that extends beyond low-level visual similarity. Because the monkeys had no experience with the objects we tested, the results suggest that monkeys and humans share a primitive representation of object similarity that is independent of formal knowledge and cultural experience, and likely derived from common evolutionary constraints on object representation. (shrink)

Risk communicators often need to communicate probabilistic predictions. On occasion, an event with 10% likelihood will occur, or one with 90% likelihood will not – a probabilistically unexpected ou...

Introduction: Thinking, writing, and reading about the real -- Dialectic and the real : Lacan, Hegel, and the alchemy of après-coup -- 'Reality' and the real : culture as anamorphosis -- The real of sexual difference : imagining, thinking, being -- Ethics and the real : the ungodly virtues of psychoanalysis -- Politics, or, the art of the impossible.

This essay traces the development of Levinas’s conception of Judaism from 1928 to1947 with an aim to reveal how Levinas’s postwar conceptions of Jewish election and anti-historicism derive from his early treatments of the Heideggerian themes of Geworfenheit (thrownness) and historicality. In the process, I show how the similarities that Levinas perceived between Heidegger and Rosenzweig allowed him to recast Heideggerian categories in Jewish terms. Finally the essay considers the potential political implications and tensions that follow from Levinas’s concern after (...) World War II to maintain Rosenzweig’s contention that Judaism stands outside of History. (shrink)

In Republic X, the “problem of the irrational part” is this: Greek tragedy interacts with non-reasoning elements of the soul, affecting audiences in ways that undermine their reasoned views about virtue and value. I suggest that the common construal of Socrates’s critique of Greek tragedy is inadequate, in that it belies key elements of Plato’s audience psychology; specifically, the crucial role of the spirited part and the audience’s cognitive contribution to spectatorship. I argue that Socrates’s emphasis on the audience’s cognitive (...) contribution to spectatorship allows him to anticipate a non-authoritarian solution to the problem of the irrational part. (shrink)

The essay argues that Mary Astell’s support of the theocentric philosophy of Nicolas Malebranche embroiled her in the fray of anti-Spinozism in the late seventeenth and early eighteenth century. Because of her dawning awareness of contemporaries’ associations of Malebranche’s occasionalism with the Spinozist doctrine of one substance, Astell retracted her previous endorsement of this theory in 1694. When contemporaries briefly turned the accusation of Spinozism against Locke and his followers in the early 1700s, however, Astell felt free to return to (...) a support of Malebranche. (shrink)

Nuclear speckles are eukaryotic nuclear bodies enriched in splicing factors. Their exact purpose has been a matter of debate. The different proposed roles of nuclear speckles are reviewed and an additional layer of function is put forward, suggesting that by accumulating splicing factors within them, nuclear speckles can buffer the nucleoplasmic levels of splicing factors available for splicing and thereby modulate splicing rates. These findings build on the already established model that nuclear speckles function as a storage/recycling site for splicing (...) factors. Many studies have demonstrated proximity between nuclear speckles and sites of active transcription, suggesting that this juxtaposition can enhance the rates of gene expression. It is found that nuclear speckle disassembly increases splicing factor availability in the nucleoplasm, leading to an increase in splicing rates and faster release of nascent transcripts from the gene after transcription. Altogether, this era in which genomic and imaging approaches are applied to study nuclear organization has expanded the outlook on the possible roles of nuclear speckles. (shrink)

Farm to institution programs represent alternative supply chains that aim to organize the activities of local producers with institutions that feed the local community. The current study demonstrates the value of structuration theory :75–80, 1983; The constitution of society: outline of the theory of structuration. University of California Press, Berkeley, 1984) for conceptualizing how FTI agents create, maintain, and change organizational structures associated with FTI and traditional supply chains. Based on interviews with supply chain agents participating in FTI programs, we (...) found that infrastructure, relationships, and pricing were seen as important factors that enabled and constrained FTI organizing. Additionally, we describe how FTI organizing serves to simultaneously reinforce and challenge the practices associated with traditional supply chains. Theoretical and practical implications are discussed as well as directions for future research. (shrink)

In his commentary on the first Aphorism of Hippocrates Maimonides lists the seven parts of medicine. Scholars have studied the relation of this text to the work of al-Fārābī. In particular, they have focused on the Iḥṣāʼ al-ʼulῡm, which in its present form does not contain a discussion of medicine, and on al-Fārābīʼs Risāla fi al-ţibb. The article examines the medieval Hebrew versions of the Iḥṣāʼ al-ʽūlum. On the basis of these versions, it is argued that there existed a version (...) of the Ihşāʼ al-ʽulūm which did contain a section on medicine; that the Risala fi al-ţibb could have originated in such a fuller version of the Ihsa' al-'ulum; and that Maimonides's ultimate source for his classification of medicine was probably the Iḥṣāʼ al-ʽulūm. An appendix to the paper examines Maimonides's references to Galen and to Abū Bakr al- Rāzī. These references show Maimonides's perception of al-Fārābīʼs view of physicians who claim to be philosophers. Dans son commentaire sur le premier aphorisme d'Hippocrate, Maïmonide décrit les sept parties de la médecine. Dans le passé, les chercheurs ont étudié le rapport de ce texte avec l'œuvre d'al-Fārābī, surtout le Iḥṣāʼ al-ʼulῡm et la Risāla fi al-ţibb. L'article examine les traductions hébraïques médiévales du Iḥṣāʼ al-ʽulūm. Ces traductions suggèrent l'existence d'une version, aujourd'hui disparue, du Iḥṣāʼ al-ʼulῡm, contenant une section sur la médecine. II est possible que la Risāla fi al-ţibb trouve son origine dans cette version, et il semble que la taxonomie de la médecine offerte par Maïmonide est issue, en dernière analyse, du Iḥṣāʼ al-ʼulῡm. Un appendice examine les références faites par Maïmonide à Galien et à Abū Bakr al-Rāzī, et prend note de ce que Maïmonide croyait être l'opinion d'al- Fār¯bī sur les médecins qui se prennent pour des philosophes. (shrink)

WQ.1 “Independent men and women, in independent homes, leading separate and independent lives, with full freedom to form and dissolve relations, and with perfectly equal opportunities to happiness, development, and love.” I leave out the word “rights,” doubtful I can use it without being misunderstood. Perhaps I can succeed in dispensing with its use altogether. This ideal, so stated, is attractive to me and completely in harmony with my idea of the course in life which will best further human happiness. (...) WQ.2 I am not sure that I quite understand Victor’s position in regard to the number of.. (shrink)