The paper is devoted to modelling of cell differentiation in an initially homogeneous cell population. The mechanism which provides coexistence of two cell lineages in the initially homogeneous cell population is suggested. If cell differentiation is initiated locally in space in the population of undifferentiated cells, it can propagate as a travelling wave converting undifferentiated cells into differentiated ones. We suggest a model of this process which takes into account intracellular regulation, extracellular regulation and different cell types. They include undifferentiated (...) cells and two types of differentiated cells. When a cell differentiates, its choice between two types of differentiated cells is determined by the concentrations of intracellular proteins. Differentiated cells can either stimulate differentiation into their own cell lineage or into another cell lineage. In the case of the positive feedback, only one lineage of differentiated cells will finally appear. In the case of negative feedback, both of them can coexist. In this case a periodic spatial pattern emerges behind the wave. (shrink)

Badawī, ʻAbd al-Raḥmān, 1917-2002; criticism and interpretation.

John Stuart Mill's Utilitarianism continues to serve as a rich source of moral and theoretical insight. This collection of articles by top scholars offers fresh interpretations of Mill's ideas about happiness, moral obligation, justice, and rights. Applying contemporary philosophical insights, the articles challenge the conventional readings of Mill, and, in the process, contribute to a deeper understanding of utilitarian theory as well as the complexity of moral life.

This book examines Augustine's description of the actually existing world, especially that aspect most important for the human pursuit of happiness: the human being and God. It begins with an overview of the characteristics of the human individual and the context in which they must live out their lives, a context dominated by two seemingly contradictory realities: the existence of God and the existence of evil.

Collection of 15 works of Śaṅkarācārya; includes commentary in Malayalam.

Yâsîn sûresi 13-29. âyetlerde anlatılan Ashâbü’l-karye kıssasında; yer, zaman ve şahıslar müphem bırakılmıştır. Bu makalede Ashâbü’l-karye kıssasındaki müphemlerin açıklanma imkânı sorgulanırken, tefsir geleneğindeki yorumlar ve nesnel nitelikleri resmedilmeye çalışılacaktır. Araştırmada; ilk dönem müfessirlerin müphem bırakılan unsurları açıklamaya çalıştıkları ve bu konuda birçok rivâyet naklettikleri tespit edilmiştir. Çalışmada bu rivâyetler arasında hicri dördüncü asır sonrası yapılmaya başlanan tercihler değerlendirilmiştir. Ayrıca altıncı ve özellikle yedinci asırdan itibaren kıssa hakkında aktarılan bilgilere yöneltilen eleştiriler incelenmiştir. Bu eleştirilerin genellikle; âyetlerin zâhiri, Ahd-i cedîd, tarihi bilgiler (...) ve İslâmî teoloji kaynak gösterilerek yapıldığı saptanmıştır. Kur’ân, hadis, Ahd-i Cedîd, tarih, coğrafya ve arkeolojiden günümüze kadar elde edilen bilgiler, Ashâbü’l-karye kıssası hakkındaki rivâyetleri ne kesin bir şekilde doğrular ne de net bir şekilde yalanlar. Ashâbü’l-karye kıssası hakkında yapılan yorumlar ve bunlar üzerine makalede ortaya konan tetkikler sonucunda; tefsirde rivâyetlere koşulsuz itimat ne kadar yanıltıcı ise nesnel bir dayanağı olmaksızın ortaya konulan her mantıksal çıkarıma, eleştiri ve dirâyet unsuruna mutlak güvenin de bir o kadar doğrudan uzaklaştırıcı olduğu görülmüştür. (shrink)

The outline of modern macroeconomics took shape in Britain in the early nineteenth century thanks, in part, to David Ricardo, one of the most influential economists of the time. Britain was challenged by monetary inflation, industrial unemployment and the loss of jobs abroad. Ricardo pointed the way forward. As a financier and Member of Parliament, he was well versed in politics and commercial affairs. His expertise is shown by the practicality of his proposals, including the resumption of the gold standard, (...) which was essential given the destabilizing policy of the Bank of England. Ricardo's expertise appears also in his debate with T. R. Malthus about whether an industrial economy can suffer a prolonged depression. Say's Law of Markets and the Quantity Theory of Money figure prominently in his works, but not in an extreme form. He was instead a subtle theorist, recognizing the non-neutrality of money, trade depressions and unemployment. (shrink)

HSÜN Tzu's essay on "Rectifying Terms" is justly considered a work of "great logical interest." For in this essay, one finds a remarkably modern concern with such topics as the rationale for having terms; the empirical and pragmatic bases for the classification of terms; the formation of generic and specific terms; the importance of observing established linguistic practices; the necessity of complying with proper standards for the institution, ratification, and regulation of the uses of language ; the nature of argumentative (...) discourse ; and the problems inherent in successful linguistic communication. A careful examination of some passages in other essays also suggests an awareness of the distinction between deductive, inductive, and analogical inferences, though Hsün Tzu provides us no explicit discussion of the nature of reasoning and its validating rules. (shrink)

Professor Solmsen's interpretation is orthodox; his comprehensive account builds on recent more specialized studies, including his own, and those of Jaeger, Ross, and Cherniss. If in some ways the book contains no large surprises, it nevertheless makes a major contribution by its treatment of Plato. The author has skillfully disengaged Plato's observations about nature from the customary ethical, epistemic, or, as the case may be, metaphysical contexts. He demonstrates that Plato was toward the end of his career a more serious (...) investigator of physical phenomena than is commonly supposed. Moreover, at almost every turn he finds Platonic precedents for Aristotle's thinking in this field. He does not detract from Aristotle's originality, but illumines it, and Plato's as well. (shrink)

Hannibal's trek through western Europe has fascinated ancient and modern historians alike. Although most attention has been focused on determining his route through the Alps, a less popular question, the site of his Rhône crossing, has been by no means neglected. Many scholars have offered differing solutions to this problem, but all agree on one point: that Hannibal transported his elephants across the Rhône by raft. No doubt this consensus stems from the fact that both Polybius and Livy, who give (...) almost identical versions of the crossing, agree on this mode of transport. But an analysis of their accounts will show that the use of rafts was neither necessary nor desirable and that a more likely method is contained in an alternative version that Livy records, then rejects in favour of Polybius' account. (shrink)

Hegel’s basic position so far on the various meanings of evil as necessary and thereby intelligible directly in the development of spirit might be summed up as follows. Evil is always a necessary moment of instability which gives impetus in the movement from various meanings of particularity to various meanings of universality; from the more abstract expression of potential unity and truth to the more actualized notion and unity.

An introductory work on the various school of Indian philosophy.

Not everyone agreed with Barker when he wrote those words. Few students of the Politics would agree with him today. Disagreement comes from different sides. On one hand--the "rights" hand, one might call it--Karl Popper argued in 1945 in The Open Society and its Enemies that Aristotle's essentialism was less interesting than Platonism but equally congenial to modern totalitarianism. On the other hand--call it the "anti-rights" hand --scholars such as Alasdair MacIntyre and the legal historian Michel Villey would have it (...) that the whole modern conception of rights, especially human or natural rights, is a pernicious fabrication of the Enlightenment, with roots going back no further than the similarly pernicious nominalism of William of Ockham. As far as the current consensus is concerned, then, whether one favors rights or not, and whether one admires Aristotle or not, there are no rights--or at least no individual natural rights--in Aristotle. (shrink)

Among major contractarian theorists, David Gauthier has the most ambitious philosophical aims. John Rawls has recently made clear that his theory of justice is not intended to provide a timeless and culturally invariant account of justice derived from the theory of rational choice. Yet Gauthier, in his rightly acclaimed and widely influential writings, attempts to provide just such an account of morality and distributive justice. With this new publication of a collection of his most important articles from the past two (...) decades following, by four years, the appearance of his systematic treatise on ethics we are now in a good position to assess Gauthier's moral theory. (shrink)

Comprehensive analysis of fundaentals of Sankhya philosophy with reference to Vedic literature and Śaṅkarācārya.

Interpretation of Śaṅkarācārya's Brahmasūtrabhāṣyam; includes original text.

SummaryThe paper undertakes to disentangle the problem facing Kant's Third Antinomy from the problems confronting the transcendental reality of time and the distinction between things–in–themselves and appearances. Three different resolutions of the Third Antinomy are distinguished. It is shown that neither the appeal to the transcendental ideality of time nor to the distinction between things‐in‐themselves and appearances in the first Kritik resolution succeeds in resolving the antinomy as Kant states it. The appeal in the Groundwork to the distinction between heteronomy (...) and autonomy shifts the problem. And the reliance in the second Kritik on our ability to know a priori that there are necessary connections in our experience fails in yet another way to forestall the antinomy. The common core of all of these difficulties lies in what is called here the Duplication Problem: The tendency of the distinctions introduced to resolve the problem to duplicate the very antinomy they are supposed to resolve. Finally, it is shown how isolating these issues helps to strengthen Kant's argument for transcendental ideality and to clarify the conditions under which the antinomy can he resolved. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:MACINTYRE'S POSTMODERN THOMISM: REFLECTIONS ON THREE RIVAL VERSIONS OF MORAL ENQUIRY THOMAS s. HIBBS Boston College Chestnut Hill, Massachusetts IN A RECENT issue of The Thomist, J. A. DiNoia, O.P., argues that certain themes in post-modern thought provide an occasion for the recovery of neglected features of the Catholic tradition.1 DiNoia focuses on three motifs : first, a " broader conception of rationality," with an emphasis on the " (...) role of tradition and authority," second, attention to the " role of texts and narrative in shaping thought and culture," and, third, the " importance of community in fostering personal identity." These themes have been prominent in the writings of Alasdair Macintyre. In his latest publication, Three Rival Versions of Moral Enquiry, he brings the Augustinian-Thomistic tradition into conversation with its principal rivals, encyclopaedia and genealogy.2 The dialogical character of the work, the text of his Gifford Lectures, affords Macintyre the opportunity to sharpen and develop his views of rationality, of the connection between particularism and universalism, and of the Christian contribution to moral inquiry. What emerges from the series of dialectical encounters is a constructive, postmodern Thomism, one which is not susceptible to the genealogical critique of encyclopaedia and which circumvents the self-destructive tendencies of genealogy. 1 " American Catholic Theology at Century's End: Postconciliar, Postmodern, and Post-Thomistic," The Thomist 54 (1990), pp. 499-518. 2 The seminal text for each of the three rival versions was published in the 1860's: for encyclopaedia, The Ninth Edition of Encyclopaedia Brittanica, for genealogy, Nietzsche's Genealogy of Morals, and for tradition or Thomism, Aeterni Patris. 277 278 THOMAS S. HIBBS According to Macintyre, the terms of the debate over rationality between genealogy and encyclopedia have obscured apprehension of the Thomistic alternative. As they see it, " Either reason is thus impersonal, universal, and disinterested or it is the unwitting representative of particular interests, masking their drive to power by its false pretensions to neutrality and disinterestedness." But the mutually exclusive way of putting the question conceals a third possibility, the possibility that reason can only move towards being genuinely universal and impersonal insofar as it is neither neutral nor disinterested, that membership in a particular type of moral community, one from which fundamental dissent has to be excluded, is a condition for genuinely rational inquiry.3 The passage introduces the salient features of Macintyre's view of the relationship between particularism and universalism.4 Macintyre develops his view not only in confrontation with genealogy and encyclopaedia, but also out of the Thomistic tradition. In a chapter entitled, "Too Many Thomisms? ", Macintyre describes the history of the revival of Thomism after Aeterni Patris.5 Macintyre criticizes early neo-Thomism for reading Aquinas as a systematic thinker, whose project was fundamentally epistemological. By beginning with ·epistemology, neoThomism distorted Aquinas's texts, cast the terms of the debate between Aquinas and modernity in the distinctively modern language of epistemic justification, and predictably reenacted the futile history of modern philosophy.6 Macintyre observes that there are simply "too many ways to begin." But even early on a Three Rival Versions of Moral Enquiry (Notre Dame: University of Notre Dame Press, 1990), pp. 59-60. Henceforth referred to as TRV. 4 Many critics have misunderstood Maclntyre's insistence on the particularist means to universality. For a careful and sympathetic discussion of this question, see John Doody, " Macintyre and Habermas on Practical Reason,'' American Catholic Philosophical Quarterly, LXV (1991), pp. 143-58. s TRV, pp. 58-81. 6 See the quite different understanding of this history in Gerald McCool's From Unity to Pluralism: The Internal Evolution of Thomism (New York: Fordham University Press, 1989) and "Why St. Thomas Stays Alive,'' International Philosophical Quarterly 30 (1990), pp. 275-288. THREE RIVAL VERSIONS OF MORAL ENQUIRY 279 there was an acknowledgement by Kleutgen, among others, of the disparity between pre- and post-Cartesian philosophy. Still, early neo-Thomism failed to see that the break came not with Descartes but with Scotus. Hence, the decidedly unThomistic influence of Scotus upon Suarez-whose authority was crucial in the rehabilitation of Aquinas-was unconsciously incorporated into neo-Thomism.7 The result of early neo-Thomism was an unhappy assimilation... (shrink)