Introduction Social anxiety disorder (SAD) symptoms are maintained by cognitive biases, which are overestimations of the severity and likelihood of negative social events (cost/probability biases), and by sensitivity to rewards and punishments that are determined according to behavioral inhibition/behavioral activation systems (BIS/BAS). Cost/probability biases might activate the behavioral immune system and exacerbate the avoidance of social events. Earlier studies have proposed that low BIS or high BAS decrease SAD symptoms; BIS/BAS may even change the effects of cognitive biases on SAD (...) symptoms. Hence, the current study investigates the interaction effects of BIS/BAS and cost/probability biases on SAD symptoms. Method Seventy-six Japanese undergraduate students completed the Japanese version of the Liebowitz Social Anxiety Scale (LSAS), which comprises Fear and Avoidance subscales, the BIS/BAS Scale, and the Social Cost Probability Scale. Results A multiple regression analysis was performed to examine whether cost/probability biases, BIS/BAS, and their interactions affected SAD symptoms; following this, the main effects of cost bias and BIS were determined for LSAS-Fear (β =.64, p <.001; β =.33, p <.01) and LSAS-Avoidance (β =.49, p <.001; β =.35, p <.01). The interaction effect between cost bias and BAS was significant for LSAS-Avoidance (β = −.32, p <.05). Simple slope analysis showed that the slope of cost bias was significant for low-BAS individuals (β =.77, p <.001) but not for high-BAS individuals (β = −.21, n.s.). The interaction effect between probability bias and BAS was significant for LSAS-Avoidance (β =.40, p <.01) as well. Further, simple slope analysis revealed that the slope of probability bias was significant for low-BAS individuals (β = −.53, p <.05) but not for high-BAS individuals (β =.17, n.s.). Discussion The study found interesting results with respect to the avoidance of social events. Low-BAS individuals with high cost or low probability biases regarding social events may have a tendency to avoid social events. In contrast, if high-BAS individuals overestimate the cost of social events or underestimate the probability of social events, their anticipation of rewards might prevent them from avoiding social events. (shrink)

This volume presents the first unabridged translation of Ito Jinsai's (1627-1705) masterwork, the Gomo jigi (Philosophical Lexicography of the Analects and ...

慶応義塾大学法学部のゼミナール「伊東乾民事訴訟法研究会」の卒業生の会「乾会」による論文集。今回はテーマを民事訴訟法に限ることなく、現在関心を持っている法律分野について執筆した。.

Reinforcement learning is very effective for robot learning. Because it does not need priori knowledge and has higher capability of reactive and adaptive behaviors. In our previous works, we proposed new reinforcement learning algorithm: “Q-learning with Dynamic Structuring of Exploration Space Based on Genetic Algorithm (QDSEGA)”. It is designed for complicated systems with large action-state space like a robot with many redundant degrees of freedom. And we applied it to 50 link manipulator and effective behavior is acquired. However optimality and (...) fault tolerance of the proposed algorithm were not considered and to demonstrate effectiveness of the proposed algorithm other applications are necessary. Acquiring of locomotion patterns by a multi-legged robot is a very interesting problem. As it has many redundant degrees of freedom, application of usual reinforcement learning is difficult and an optimal locomotion has not been acquired using previous reinforcement learning algorithm. And the redundancy of the robot is effective to the fault tolerance and various locomotion patterns can be acquired for adapting the faults of the legs. In this paper, we applied QDSEGA to acquiring of locomotion pattern by the multi-legged robot and considered the optimality and fault tolerance. Effective behavior has been obtained by using our proposed algorithm. (shrink)

This study investigated the circumstances and problems that departments of forensic medicine encounter with bereaved families regarding samples obtained from medico-legal autopsies. A questionnaire was posted to all 76 departments of forensic medicine performing medico-legal autopsies in Japan, and responses were received from 48 . Of the respondents, 12.8% had approached and communicated with bereaved families about collecting samples from the deceased person during an autopsy and the storage of the samples. In addition, 23.4% of these had informed families that (...) samples might be used in research. Eighteen departments had received enquiries and requests from families about the samples, with most requests concerning their return. The response to such requests varied according to the department. Few departments interacted with the bereaved families regarding the procedure for obtaining autopsy samples, and their methods for handling family concerns differed depending on the person within the department authorised to contact the family. Moreover, the procedures for engaging in such communication have long been unclear, and no legal or ethical consensus or agreement with the general public has been established. It is important for researchers to further discuss the correct way for forensic medicine departments to communicate with bereaved families. (shrink)

Sleep is mandatory in most animals that have the nervous system and is universally observed in model organisms ranging from the nematodes, zebrafish, to mammals. However, it is unclear whether different sleep states fulfill common functions and are driven by shared mechanisms in these different animal species. Mammals and birds exhibit two obviously distinct states of sleep, i.e., non-rapid eye movement sleep and rapid eye movement sleep, but it is unknown why sleep should be so segregated. Studying sleep in other (...) animal models might give us clues that help solve this puzzle. Recent studies suggest that REM sleep, or ancestral forms of REM sleep might be found in non-mammalian or -avian species such as reptiles. These observations suggest that REM sleep and NREM sleep evolved earlier than previously thought. In this review, we discuss the evolutionary origin of the distinct REM/NREM sleep states to gain insight into the mechanistic and functional reason for these two different types of sleep. (shrink)

The purpose of this study was to clarify the minimum necessary educational content in the area of nursing ethics in a basic nursing education program, and the level of students’ mastery of this content, based on a Delphi study in both educational and clinical settings. A Delphi study was conducted in three rounds with faculty members who teach nursing ethics at all 158 four-year nursing universities in Japan as targeted panelists. In this study the opinions on nursing ethics of nursing (...) instructors responsible for hospital education at all 82 special functioning hospitals were reflected in the panelists’ opinions. Consensus was obtained on 41 items from a total of 63 items in 4 proposed frameworks. There were 20 items related to the Concept of nursing ethics, 7 items related to Ethical codes, 13 items related to Ethical issues and methods to resolve them, and 1 item related to Efforts and issues in practical and educational settings. Consensus as to desired level of mastery was reached on a total of 40 items. This agreed-upon level involved understanding of the concept for 22 items, the ability to explain the concept for 16 items, and the ability to act based on the concept for 2 items. (shrink)

ArgumentThis paper discusses one aspect of the context in which atomic physics developed in Japan between 1905 and 1931. It argues that during this period, there was a social context in which atomic physics was valued as a study of the electron and was thus relevant to electrical engineering. To demonstrate this, I first show that after the Russo-Japanese War, electrical engineering was deemed a valuable and viable field of research in Japan. Second, I show that physicists wrote textbooks and (...) popular accounts about the electron, covering topics from both atomic physics and electrical engineering and presenting the former as relevant to the latter. Finally, as an example of how atomic physics partially emerged from this context, I discuss the group of Kujirai Tsunetarō, an electrical engineer who worked in the physics department of the Institute for Physical and Chemical Research. From Kujirai's group, Nishina Yoshio started his career and became the most important Japanese atomic and nuclear physicist of the 1930s. (shrink)

Davide and Benedetto Ghirlandaio’s close association with their brother Domenico has made it difficult to individuate their own artistic styles and evaluate their contributions to the Ghirlandaio workshop. Benedetto’s artistic character is particularly elusive, since the Nativity in the church of Notre-Dame in Aigueperse, Auvergne, is the only work firmly attributed to him. This paper proposes a reconstruction of Benedetto’s career by reassessing the works once ascribed to a painter known as the Master of the Saint Louis Madonna. Most of (...) these paintings, centred on the eponymous work in the Saint Louis Art Museum, have been incorporated into Davide’s oeuvre. Stylistic analysis, however, reveals their distinct artistic character and uncovers numerous points of comparison with the Aigueperse Nativity. On that basis they are reattributed here to the young Benedetto in his initial Florentine period. This identification is also corroborated by an analysis of his sojourn in France between 1486 and 1493, where he developed his technical skills and his interest in Netherlandish painting, possibly through the interaction with the Master of Moulin. The paper then goes on to an examination of his activities after his return to Florence, and the ways in which he integrated his experience gained in France into the late Ghirlandaio workshop style. Benedetto’s artistic development revealed by this reconstruction suggests a rich cross-fertilisation within the Florentine workshops in the late fifteenth century, with particular focus on the artists around the Verrocchio workshop in the early 1480s and those who participated in the Ghirlandaio workshop after Domenico’s death. Also, as Benedetto was one of the few Italian painters who worked north of the Alps, the reappraisal of his career offers insights into the ways in which travelling artists could interact with local artistic environments and develop their own styles. (shrink)

Die neuere Naturwissenschaft trat im 17. Jahrhundert zuerst als “Physik” auf. Man soll sich an die Gründung der modernen Dynamik von Galileo und Newton erinnern.Die methodisch-allgemeine Grundlegung dieser neuen Wissenschaft wird in der Cartesischen Philosophie am klarsten ausgedrückt.

Reinforcement learning has recently received much attention as a learning method for complicated systems, e.g., robot systems. It does not need prior knowledge and has higher capability of reactive and adaptive behaviors. However increase in dimensionality of the action-state space makes it diffcult to accomplish learning. The applicability of the existing reinforcement learning algorithms are effective for simple tasks with relatively small action-state space. In this paper, we propose a new reinforcement learning algorithm: “Q-learning with Dynamic Structuring of Exploration Space (...) Based on Genetic Algorithm ”. The algorithm is applicable to systems with high dimensional action and interior state spaces, for example a robot with many redundant degrees of freedom. To demonstrate the effectiveness of the proposed algorithm simulations of obstacle avoidance by a 50 links manipulator have been carried out. It is shown that effective behavior can be learned by using the proposed algorithm. (shrink)

We investigated the effects of everyday language exposure on the prediction of orthographic and phonological forms of a highly predictable word during listening comprehension. Native Japanese speakers in Tokyo (Experiment 1) and Berlin (Experiment 2) listened to sentences that contained a predictable word and viewed four objects. The critical object represented the target word (e.g., /sakana/;fish), an orthographic competitor (e.g., /tuno/;horn), a phonological competitor (e.g., /sakura/;cherry blossom), or an unrelated word (e.g., /hon/;book). The three other objects were distractors. The Tokyo (...) group fixated the target and the orthographic competitor over the unrelated objects before the target word was mentioned, suggesting that they pre-activated the orthographic form of the target word. The Berlin group showed a weaker bias toward the target than the Tokyo group, and they showed a tendency to fixate the orthographic competitor only when the orthographic similarity was very high. Thus, prediction effects were weaker in the Berlin group than in the Tokyo group. We found no evidence for the prediction of phonological information. The obtained group differences support probabilistic models of prediction, which regard the built-up language experience as a basis of prediction. (shrink)

Background: Chief nurses are most likely to take the lead in discussing and working to resolve ethical dilemmas, creating an ethical culture within their organization that results in effective ethics training. As the first step in this process, there is a need to define the kinds of ethical dilemmas that chief nurses grapple with on a regular basis as a target for future study. Research design: Anonymous written questionnaires and semi-structured interviews. Ethical considerations: All research procedures were approved by the (...) Chubu University Ethics Review Board, the research institution to which the authors belong (authorization no. 250016). Findings and discussion: Responses from four chief nurses indicated that ethical dilemmas could be categorized as either those related to patient dignity or those related to management (unique to their roles as administrators). It was also learned that chief nurses struggle with the fact that although they consult with their superiors and others, these efforts do not lead to resolution. The expectation is that going forward, chief nurses will play a central role in acting as coordinators with physicians to promote better communication as well as lead group discussions aimed at providing care that respects patient dignity. (shrink)

Spatial metaphors of affect display remarkable consistencies across languages in mapping sensorimotor experiences onto emotional states, reflecting a great degree of similarity in how our bodies register affect. At the same time, however, affect is complex and there is more than a single possible mapping from vertical spatial concepts to affective states. Here we consider a previously unreported case of spatial metaphors mapping down onto desirable, and up undesirable emotional experiences in Mlabri, an Austroasiatic language of Thailand and Laos, making (...) a novel contribution to the study of metaphor and Cognitive Linguistics. Using first-hand corpus and elicitation data, we examine the metaphorical expressions: klol jur ‘heart going down’ and klol khɯn ‘heart going up’/klol kɔbɔ jur ‘heart not going down’. Though reflecting a metaphorical mapping opposite to the commonly reported happy is up metaphor, which is said to link to universal bodily correlates of emotion, the Mlabri metaphors are far from idiosyncratic. Rather, they are grounded in the bodily experience of positive low-arousal states, and in that reflect an emic view of ideal affect centered on contentment and tranquility. This underscores the complexity of bodily experience of affect, demonstrating that cultures draw on the available sensorimotor correlates of emotion in distinct ways. (shrink)

Researchers and non-commercial institutions negotiate complex legislation and guidance when planning and conducting research studies. The documents and processes required differ across nations and their regulatory bodies and it can be challenging to conduct an international study, especially for non-commercial organisations. In this study, colleagues from Japan and the UK worked closely together focusing on the legislation, organisations, trial processes, ethics review and quality assurance frameworks of clinical trials in two countries, the UK, demonstrated on the model of practices in (...) the University of Bristol and University Hospital Bristol NHS Foundation Trust, and Japan, based on the model in Kyoto University Hospital. Although the ICH tripartite guidelines were developed with participation from both the EU and Japan the set-up and approval processes for clinical trials are different between the two countries while the expectations for quality assurance are similar. We will argue that the f... (shrink)

十九世紀後半における英国唯美主義を支えた日本趣味の実態はどのようなものだったのか。ロセッティ、スウィンバーン、ペイター、ワイルド、ホイッスラーらの藝術について、さらに英国唯美主義の素地としてのギリシア のエピクーロス的世界、西脇順三郎を初めとする日本の詩人達とワイルド受容、ロセッティやペイターの系譜に連なる唯美主義者としてのハーンなど、両国の藝術の関わりを悠遠な視座から読み解く比較藝術論。図版多数。 .

Organisms must adapt to environmental stresses to ensure their survival and prosperity. Different types of stresses, including thermal, mechanical, and hypoxic stresses, can alter the cellular state that accompanies changes in gene expression but not the cellular identity determined by a chromatin state that remains stable throughout life. Some tissues, such as adipose tissue, demonstrate remarkable plasticity and adaptability in response to environmental cues, enabling reversible cellular identity changes; however, the mechanisms underlying these changes are not well understood. We hypothesized (...) that positive and/or negative “Integrators” sense environmental cues and coordinate the epigenetic and transcriptional pathways required for changes in cellular identity. Adverse environmental factors such as pollution disrupt the coordinated control contributing to disease development. Further research based on this hypothesis will reveal how organisms adapt to fluctuating environmental conditions, such as temperature, extracellular matrix stiffness, oxygen, cytokines, and hormonal cues by changing their cellular identities. (shrink)