Xenotransplantation - the transfer of living tissue between species - has long been heralded as a potential solution to the severe organ shortage crisis experienced by the United Kingdom and other 'developed' nations. However, the significant risks which accompany this biotechnology led the United Kingdom to adopt a cautious approach to its regulation, with the establishment of a non-departmental public body - UKXIRA - to oversee the development of this technology on a national basis. In December 2006 UKXIRA was quietly (...) disbanded and replaced with revised guidance, which entrusts the regulation of xenotransplantation largely to research ethics committees. In this article we seek to problematize this new regulatory framework, arguing that specialist expertise and national oversight are necessary components of an adequate regulatory framework for a biotechnology which poses new orders of risk, challenges the adequacy of traditional understandings of autonomy and consent, and raises significant animal welfare concerns. We argue for a more considered and holistic approach, based on adequate consultation, to regulating biotechnological developments in the United Kingdom. (shrink)

On the dominant interpretation, Schopenhauer possesses a will to will view of boredom: boredom consists in the dissatisfaction of a second-order desire to pursue objects of first-order desire. I ch...

This paper details a three-credit-hour undergraduate ethics course that was delivered using traditional, distance, and compressed formats. OLS 263: Ethical Decisions in Leadership is a 200-level course offered by the Department of Organizational Leadership and Supervision in the Purdue School of Engineering and Technology at Indiana University Purdue University Indianapolis (IUPUI). Students in engineering, technology, business, nursing, and other majors take the course. In an effort to determine student perceptions of course and instructor effectiveness, end-of-course student survey data were compared (...) using data from traditional, distance, and compressed sections of the course. In addition, learning outcomes from the final course project were evaluated using a standardized assessment rubric and scores on the course project. (shrink)

Journal of Social Philosophy, EarlyView.

The obesity epidemic among children and adolescents in the United States continues to worsen. The most recent analysis of data from the National Health and Nutrition Examination Survey showed that the prevalence of overweight among children and adolescents – defined as a Body Mass Index at or above the 95th percentile on gender-specific BMI-for-age growth charts developed by the Centers for Disease Control and Prevention – increased significantly between 1999-2000 and 2003-2004. Over this period, the prevalence of overweight among children (...) and adolescents aged 2-19 increased 23% – from 13.9% to 17.1%. In 2003-2004, 18.8% of children aged 6-11 and 17.4% of adolescents aged 12-19 were overweight. Roughly comparable proportions of each age group were considered to be at risk of becoming overweight. (shrink)

Over the last couple of decades, a call has begun to resound in a number of distinct fields of inquiry for a reattachment of form to matter, for an understanding of ‘information’ as inherently embodied, or, as Jean-Marie Lehn calls it, for a “science of informed matter.” We hear this call most clearly in chemistry, in cognitive science, in molecular computation, and in robotics—all fields looking to biological processes to ground a new epistemology. The departure from the values of a (...) more traditional epistemological culture can be seen most clearly in changing representations of biological development. Where for many years now, biological discourse has accepted a sharp distinction between information and matter, software and hardware, data and program, encoding and enactment, a new discourse has now begun to emerge in which these distinctions have little meaning. Perhaps ironically, much of this shift depends on drawing inspiration from just those biological processes which the discourse of disembodied information was intended to describe. (shrink)

Sexual competition in the epics is looked at for examples of conflict between older or more powerful males and younger or subordinate males over fertile females, a pattern that would have characterized the human environment of evolutionary adaptation (EEA). In the Iliad and Odyssey, the Old Testament, the Arthurian Cycle (and its Celtic originals), the Volsunga Saga, and El Cid, this pattern is found to be the frame or prime mover or a central feature of the narrative. It is suggested (...) that changes through time in the literary treatment of the theme reflect a progressive dilution of the traditional power of older males over mate choice. (shrink)

Previous studies show that reading sentences about actions leads to specific motor activity associated with actually performing those actions. We investigate how sign language input may modulate motor activation, using British Sign Language sentences, some of which explicitly encode direction of motion, versus written English, where motion is only implied. We find no evidence of action simulation in BSL comprehension, but we find effects of action simulation in comprehension of written English sentences by deaf native BSL signers. These results provide (...) constraints on the nature of mental simulations involved in comprehending action sentences referring to transfer events, suggesting that the richer contextual information provided by BSL sentences versus written or spoken English may reduce the need for action simulation in comprehension, at least when the event described does not map completely onto the signer's own body. (shrink)

Conley and colleagues (2023) conduct a fascinating analysis of how influential organizations in the global governance of human genome editing debate conceptualize and perform public engagement. Whi...

This study uses the Religion and State round 2 dataset to examine the presence of religious freedom in 177 countries. There are many different conceptions of the meaning of religious freedom but they can be divided into two categories, those which focus on the free exercise of religion—that is the right to practice religion and maintain religious institutions—and those which focus on treating all religions equally, also known as the level playing field model. The results show that neither form of (...) religious freedom is common even among democracies and states which have constitutional clauses protecting religious freedom. This finding has serious implications for our understanding of the nature of liberal democracy. (shrink)

The Routledge Handbook of Philosophy and Media Ethics is an outstanding survey and assessment of this vitally important field. Essential reading for students and researchers in philosophy, media and communication studies, politics and law, as well as practicing media professionals and journalists.

One of Alfred North Whitehead’s Lowell lectures of 1925 encapsulated a common belief about the relations between science and romanticism. In a chapter on “The romantic reaction” in the published version of the lectures, Whitehead presented science and the romantic spirit as fundamentally at odds (Whitehead 1926, chapter 5). The romantic world view, for Whitehead, had no place for perceptions of nature as an unfeeling law-bound machine. Against the conventional scientific virtues of objectivity, it stressed subjectivity, and against the model (...) of inexorable determinism, it favored one closer to that of an organism, with the potential for growth and change. It is not hard to see the core of truth in Whitehead’s interpretation. When Wordsworth wrote “We murder to dissect,” he was voicing a romantic sensibility that saw the abstraction of science as, at best, scratching the surface of a natural world at once richer and closer to us as human beings than the one handed down by the mechanical .. (shrink)

The author argues that our best hope for addressing world problems (from climate change to violence, to poverty) is to teach critical thinking through the study of language and all symbol systems. This means removing disciplinary boundaries so that we can focus more effectively on solving common problems. Human survival also depends upon our critical analysis of electronic media and our wise uses of technology. Critical thinking via all symbol systems is more likely to generate humane actions. Therefore, education—not governments (...) or armies or institutions or private corporations—is our best hope. (shrink)

Bandits in Print: The Water Margin and the Transformations of the Chinese Novel. By Scott W. Gregory. New York: Cornell University Press, 2023. Pp. xii + 179. $125 (cloth); $26.95 (paper); open access.

It is a platitude among decision theorists that agents should choose their actions so as to maximize expected value. But exactly how to define expected value is contentious. Evidential decision theory (henceforth EDT), causal decision theory (henceforth CDT), and a theory proposed by Ralph Wedgwood that this essay will call benchmark theory (BT) all advise agents to maximize different types of expected value. Consequently, their verdicts sometimes conflict. In certain famous cases of conflict—medical Newcomb problems—CDT and BT seem to get (...) things right, while EDT seems to get things wrong. In other cases of conflict, including some recent examples suggested by Andy Egan, EDT and BT seem to get things right, while CDT seems to get things wrong. In still other cases, EDT and CDT seems to get things right, while BT gets things wrong. It's no accident, this essay claims, that all three decision theories are subject to counterexamples. Decision rules can be reinterpreted as voting rules, where the voters are the agent's possible future selves. The problematic examples have the structure of voting paradoxes. Just as voting paradoxes show that no voting rule can do everything we want, decision-theoretic paradoxes show that no decision rule can do everything we want. Luckily, the so-called “tickle defense” establishes that EDT, CDT, and BT will do everything we want in a wide range of situations. Most decision situations, this essay argues, are analogues of voting situations in which the voters unanimously adopt the same set of preferences. In such situations, all plausible voting rules and all plausible decision rules agree. (shrink)

G. E. M. Anscombe’s Intention is a classic of twentieth-century philosophy. The work has been enormously influential despite being a dense and largely misunderstood text. It is a standard reference point for anyone engaging with philosophy of action and philosophy of psychology. In this Routledge Philosophy GuideBook, Rachael Wiseman: situates _Intention_ in relation to Anscombe’s moral philosophy and philosophy of mind considers the influence of Aquinas, Aristotle, Frege, and Wittgenstein on the method and content of _Intention_ adopts a structure (...) for assessing the text that shows how Anscombe unifies the three aspects of the concept of intention considers the influence and implications of the piece whilst distinguishing it from subsequent work in the philosophy of action Ideal for anyone wanting to understand and gain a perspective on Elizabeth Anscombe’s seminal work, this guide is an essential introduction, useful in the study of the philosophy of action, ethics, philosophy of psychology and related areas. (shrink)

A number of recent authors (Galles and Pearl, Found Sci 3 (1):151–182, 1998; Hiddleston, Noûs 39 (4):232–257, 2005; Halpern, J Artif Intell Res 12:317–337, 2000) advocate a causal modeling semantics for counterfactuals. But the precise logical significance of the causal modeling semantics remains murky. Particularly important, yet particularly under-explored, is its relationship to the similarity-based semantics for counterfactuals developed by Lewis (Counterfactuals. Harvard University Press, 1973b). The causal modeling semantics is both an account of the truth conditions of counterfactuals, and (...) an account of which inferences involving counterfactuals are valid. As an account of truth conditions, it is incomplete. While Lewis's similarity semantics lets us evaluate counterfactuals with arbitrarily complex antecedents and consequents, the causal modeling semantics makes it hard to ascertain the truth conditions of all but a highly restricted class of counterfactuals. I explain how to extend the causal modeling language to encompass a wider range of sentences, and provide a sound and complete axiomatization for the extended language. Extending the truth conditions for counterfactuals has serious consequences concerning valid inference. The extended language is unlike any logic of Lewis's: modus ponens is invalid, and classical logical equivalents cannot be freely substituted in the antecedents of conditionals. (shrink)

David Lewis’s ‘Humean Supervenience’ (henceforth ‘HS’) combines realism about laws, chances, and dispositions with a sparse ontology according to which everything supervenes on the overall spatiotemporal distribution of non-dispositional properties (Lewis 1986a, Philosophical papers: Volume II, pp. ix–xvii, New York: Oxford Univesity Press, 1994, Mind 103:473–490). HS faces a serious problem—a “big bad bug” (Lewis 1986a, p. xiv): it contradicts the Principal Principle, a seemingly obvious norm of rational credence. Two authors have tried to rescue Lewis’s ontology from the ‘big (...) bad bug’ (henceforth ‘the Bug’) by rejecting realism about laws, chances, and dispositions (Halpin 1994, Aust J Phil 72:317–338, 1998, Phil Sci 65:349–360; Ward 2005, Phil Sci 71:241–261). I will argue that this strategy cannot possibly work: it is the ontology, not the realist thesis, that lies at the root of the problem. (shrink)

The historical figure of the cow as a symbol is treasured and ancient, yet simultaneously this animal in many societies exists de facto for people’s plates. The cow, like other animals, exists in parts: as treasured symbol, and as commodity. Looking at collections by contemporary Anglophone poets, Ariana Reines, and Selima Hill, I will consider how each writer’s self-reflexive critique of animal representation reorients the material subjects of their poems, intersecting these innovative poetries with contemporary thinkers on animal studies, to (...) realize the limits of a poetic perspective on animal bodies. Both writers work either against or deliberately within a lyric mode critiqued for its objectifying address in order to interrogate modes of rendering that position the animal’s existence as a resource. From Reines’s scatological slaughterhouse to Hill’s surreal landscapes I will explore how the symbolic and literal exploitation of an animal’s “flesh” in their poems is counteracted. (shrink)

Traditional ideas of mediator neutrality and impartiality have come under increasing attack in recent decades. There is, however, a lack of consensus on what should replace them. Mediation Ethics offers a response to this question, developing a new theory of mediation that emphasises its nature as a relational process.

ABSTRACT In spite of vast global improvements in living standards, health, and well‐being, the persistence of absolute poverty and its attendant maladies remains an unsettling fact of life for billions around the world and constitutes the primary cause for the failure of developing states to improve the health of their peoples. While economic development in developing countries is necessary to provide for underlying determinants of health – most prominently, poverty reduction and the building of comprehensive primary health systems – inequalities (...) in power within the international economic order and the spread of neoliberal development policy limit the ability of developing states to develop economically and realize public goods for health. With neoliberal development policies impacting entire societies, the collective right to development, as compared with an individual rights‐based approach to development, offers a framework by which to restructure this system to realize social determinants of health. The right to development, working through a vector of rights, can address social determinants of health, obligating states and the international community to support public health systems while reducing inequities in health through poverty‐reducing economic growth. At an international level, where the ability of states to develop economically and to realize public goods through public health systems is constrained by international financial institutions, the implementation of the right to development enables a restructuring of international institutions and foreign‐aid programs, allowing states to enter development debates with a right to cooperation from other states, not simply a cry for charity. (shrink)

You have a choice -- Decision-making steps -- What is a good choice? -- Identifying options -- Making predictions -- Pros and cons -- Weighing the consequences -- Values and motivations -- Thinking of others -- Choose wisely -- Glossary -- Index -- Primary source list -- Websites.

A recent report by Blumenthal et al.1 provides convincing evidence that at least 15% of Caenorhabditis elegans genes are co‐transcribed within over a thousand operons. Polycistronic transcription of gene clusters is very rare in eukaryotes. The widespread occurrence of operons in C. elegans thus raises some interesting questions about the origin and function of these multigenic transcriptional units. BioEssays 24:983–987, 2002. © 2002 Wiley‐Periodicals, Inc.

We calculate the complexity of Scott sentences of scattered linear orders. Given a countable scattered linear order L of Hausdorff rank $\alpha $ we show that it has a ${d\text {-}\Sigma _{2\alpha +1}}$ Scott sentence. It follows from results of Ash [2] that for every countable $\alpha $ there is a linear order whose optimal Scott sentence has this complexity. Therefore, our bounds are tight. We furthermore show that every Hausdorff rank 1 linear order has an optimal ${\Pi ^{\mathrm {c}}_{3}}$ (...) or ${d\text {-}\Sigma ^{\mathrm {c}}_{3}}$ Scott sentence and give a characterization of those linear orders of rank $1$ with ${\Pi ^{\mathrm {c}}_{3}}$ optimal Scott sentences. At last we show that for all countable $\alpha $ the class of Hausdorff rank $\alpha $ linear orders is $\boldsymbol {\Sigma }_{2\alpha +2}$ complete and obtain analogous results for index sets of computable linear orders. (shrink)

Evidence exists that the UK National Health Service has had, over many years, persistent problems of negative and intimidating behaviour towards staff from other employees. The evidence also suggests the organisational responses to negative behaviour can be inadequate. A conceptual model of organisational dysfunction was proposed to assist in explaining those responses and the overall culture in the NHS. Through research this model has been tested. Based upon the findings, an extended and developed model of organisational dysfunction is presented. A (...) qualitative approach was taken to research the organisational responses to negative behaviour, and the reasons and motivations for those responses. Forty-three interviews and six focus groups were conducted. There seem to be “islands” and “pockets” with a positive culture; however, the generalised evidence suggests the NHS is systemically and institutionally deaf, bullying, defensive and dishonest, exhibiting a resistance to ‘knowing’, denial and “wilful blindness”; a dysfunctional, perverse and troubled organisation. Totalitarian and Kafkaesque characteristics are identified. The NHS could also be described as a coercive bureaucracy and under certain definitions, a corrupt entity. The NHS appears to be an organisation with a heart of darkness; a “self perpetuating dysfunctional system”. There may be widespread “learned helplessness”. It seems to be a “good news factory”, rejecting and hiding any “bad news”; retreating from reality. The NHS appears to have “lost its way” and its focus/purpose as an institution. The dysfunctional organisational behaviours manifest in the NHS need to be addressed urgently as there is a detrimental, sometimes devastating, impact on the wellbeing of both staff and patients. The NHS needs to embrace an identity of being a listening, learning and honest organisation, with a culture of respect. (shrink)