This book argues that contextually sensitive expressions have felicitous uses in which they lack unique semantic values in context. It formulates a rule for updating the Stalnakerian common ground in cases in which an accepted sentence contains an expression lacking a unique semantic value in context.

In her paper “Radical Externalism”, Amia Srinivasan argues that externalism about epistemic justification should be preferred to internalism by those who hold a “radical” worldview (according to which pernicious ideology distorts our evidence and belief‐forming processes). I share Srinivasan's radical worldview, but do not agree that externalism is the preferable approach in light of the worldview we share. Here I argue that cases informed by this worldview can intuitively support precisely the internalist view that Srinivasan challenges, offer two such cases, (...) and explain away the externalist‐friendly intuitions that Srinivasan's cases solicit. I then articulate and defend a “radical” internalism, arguing that internalists’ aversion to epistemic hubris and emphasis on subjecting one's beliefs to critical scrutiny are especially attractive in realistic cases involving multiple intersecting axes of oppression—that is, precisely the sort of case that permeates our social world. I also argue that externalism's lack of interest in action‐guiding principles leaves it with little to offer us in the fight against epistemic oppression. (shrink)

Judgments of character traits tend to be overcorrelated, a bias known as the halo effect. We conducted two studies to test an explanation of the effect based on shared lexical context and connotation. Study 1 tested whether the context similarity of trait names could explain 39 participants’ ratings of the probability that two traits would co-occur. Over 126 trait pairs, cosine similarity between the word2vec vectors of the two words was a reliable predictor of the human judgments of trait co-occurrence (...) probability (cross-validated r2 =.19, p <.001). Two measures related to word similarity increased the variation accounted for in the human judgments to 45%, cross-validated (p <.001). In Experiment 2, 40 different participants judged similarity of word meaning within the pairs, confirming that the word pairs were not simply synonymous (Average [SD] = 40.8/100 [13.1/100]). Shared lexical context and word connotation play a role in shaping the halo effect. (shrink)

This paper offers observations on people’s lived experience of the food system in Michigan during the early Covid-19 pandemic as an initial critical foray into the everyday pandemic food world. The Covid-19 crisis illuminates a myriad of adaptive food behaviors, as people struggle to address their destabilized lives, including the casual acknowledgement of the pandemic, then anxiety of the unknown, the subsequent new dependency, and the possible emergence of a new normal. The pandemic makes the injustices inherent in the food (...) system apparent across communities, demonstrating that food injustice destabilizes all members of the food system, regardless of their social location. The challenges of eating in a pandemic also reinforce the importance of building a sustainable food system; the challenges of food sovereignty and food sustainability are inextricably linked, and the pandemic lays this bare. (shrink)

Una de las características del cambio científico que ofrece más resistencia a la elaboración de un modelo teórico que permita dar cuenta de él, la constituye su carácter social. Un intento importante para vencer esa resistencia, el realizado por David Hull, se apoya en la noción de adecuación inclus..

Background: We aimed to determine the smallest changes in health-related quality of life (HRQoL) scores in the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire core 30 and the Brain Cancer Module (QLQ-BN20), which could be considered as clinically meaningful in brain cancer patients. Materials and methods: World Health Organisation performance status (PS) and mini-mental state examination (MMSE) were used as clinical anchors appropriate to related subscales to determine the minimal clinically important differences (MCIDs) in HRQoL (...) change scores (range 0-100) in the QLQ-C30 and QLQ-BN20. A threshold of 0.2 standard deviation (SD) (small effect) was used to exclude anchor-based MCID estimates considered too small to inform interpretation. Results: Based on PS, our findings support the following integer estimates of the MCID for improvement and deterioration, respectively: physical (6, 9), role (14, 12), and cognitive functioning (8, 8); global health status (7, 4(star)), fatigue (12, 9), and motor dysfunction (4(star), 5). Anchoring with MMSE, cognitive functioning MCID estimates for improvement and deterioration were (11, 2(star)) and for communication deficit were (9, 7). Estimates with asterisks were <0.2 SD and were excluded from our MCID range of 5-14. Conclusion: These estimates can help clinicians evaluate changes in HRQoL over time, assess the value of a health care intervention and can be useful in determining sample sizes in designing future clinical trials. (shrink)

Four decades after the Baby M case that led to the prohibition of commercial surrogacy in New York, much has changed in the infertility industry. Advanced technologies including the advent of gestational carrier pregnancies had made it easier and more efficient to create IVF embryos at a distance and over time, accelerating a boom in cross-border, reproductive services and allowing compensated surrogacy to flourish in a growing number of surrogacy-friendly states and beyond. For international couples, the USA has become a (...) hot spot for “circumvention tourism” given its first-rate medical care, ample supply of willing gestational carriers, burgeoning interest in family building among gay couples, and immediate USA citizenship for the child. This commentary reviews selected sociocultural and global forces that helped set the stage for the passage of the Child-Parent Security Act in New York state in 2021, and the efforts by its opponents for stronger protections not only for gestational carriers, but for gamete donors and the donor-conceived offspring. I argue that despite more responsive medical and legal guidelines, the high market demand and economic profits, combined with the lack of regulatory teeth, faulty assumptions about health risks and decision-making autonomy, and inadequate research on long-term health outcomes, continue to make compensated gestational surrogacy in the state of New York a high-risk venture without adequate informed consent. Possible unintended consequences and future research questions are proposed. (shrink)

Limitations on reproductive decision making, including forced sterilization and involuntary birth control, raise significant ethical challenges. In the United States, these issues are further complicated by a disturbing history of the abuse and victimization of vulnerable populations. One particularly fraught challenge is the risk of teratogenicity posed by moodstabilizing psychiatric medications in patients who are incapable of appreciating such dangers. Long-acting reversible contraception (LARC) offers an intervention to prevent pregnancy among individuals who receive such treatments, but at a cost to (...) their reproductive autonomy. This article examines the ethical issues involved in the use of involuntary LARC for patients on teratogenic psychiatric medications (TPMs) and argues that such an approach can only be justified as a last resort after a careful consideration of the alternatives and an assessment of potential risks and benefits. (shrink)

Hastings Center Report, Volume 52, Issue 3, Page 3-3, May–June 2022.

Table 3 was incomplete in the initial online publication. The original article has been corrected.

One of my favorite bioethics quotes is nearing 50 years old:Let us not forget that progress is an optional goal, not an unconditional commitment, and that its tempo in particular, compulsive as it may become, has nothing sacred about it. Let us also remember that a slower progress in the conquest of disease would not threaten society, grievous as it is to those who have to deplore that their particular disease be not yet conquered, but that society would indeed be (...) threatened by the erosion of those moral values whose loss, possibly caused by too ruthless a pursuit of scientific progress, would make its most dazzling triumphs not worth having.Despite its age, this invocation seems to me increasingly relevant as time... (shrink)

Die ATB ist die traditionsreichste Editionsreihe der germanistischen Mediävistik. Begründet 1881 von Hermann Paul, wurde sie von führenden Fachvertretern, Georg Baesecke, Hugo Kuhn, Burghart Wachinger, betreut. Seit 2001 liegt die Verantwortung in den Händen von Christian Kiening. Die mittlerweile etwa 120 Bände verknüpfen exemplarisch Handschriftennähe und Lesbarkeit, wissenschaftliche Arbeit am Text und Blick auf die akademische Lehre. Sie umfassen anerkannte, zum Teil kommentierte Ausgaben 'klassischer' Autoren der Zeit um 1200, aber auch veritable Werkausgaben (Notker der Deutsche) und anspruchsvolle Neueditionen (Eckenlied, (...) Heinrich von dem Türlin). (shrink)

Researchers in psychology have focused a great deal of attention on the potential greater predisposition to achievement among first-born children relative to their siblings. Focusing on the United States as an example, a time series of the first birth ratio is used to show how the changing prevalence of first births relative to higher order births has altered the composition of birth cohorts, and the ratio is decomposed into four factors. Results show that the ratio increased significantly in the 1960s (...) and early 1970s, but changed only slightly in the following decades. While more recent birth cohorts are composed of larger proportions of first-born children, the majority of children are still born as siblings. Contrary to expectations, the primary source of change was the proportion childless rather than decreasing higher order birth rates. (shrink)

This essay considers the potential role of bioethics in disaster response planning and preparedness. Bioethicists can make substantial contributions, by ensuring that decision-making and distribution of resources during crises is carried out in a fair and just manner, as well as by examining the assumptions upon which disaster planning are based. Bioethicists should also be aware of potential pitfalls of overly-hasty engagement with this new field.

The two works under review attempt to describe the outlines of a post-positivist social science of the future. Against objectivist approaches, these books emphasize the importance of hermeneutics and the cultural turn to the social sciences. Social sciences must recognize collective understandings and human agency. However, while affirming the importance of an interpretivist approach, both of these works also suggest that objective institutional reality must be recognized by social scientists today. Meaningful human agency and objective structure must be encompassed by (...) the social sciences. To this end, critical realism, originally promoted by Roy Bhaskar, figures prominently in both these books precisely because it is a theory which seems to be able to account for both agency and structure simultaneously. In fact, as both these books sometimes demonstrate, the dualistic approach represented by critical realism is flawed. By contrast, the hermeneutic approach advocated by Keith Topper and by some of the contributors to Steinmetz’s collection provides an adequate explanation of institutional social reality in and of itself. Consequently, these books can be interpreted as pointing toward a hermeneutic social science of the future. (shrink)

Contemporary critical theory and black studies have witnessed a surge in theoretical accounts of “blackness” as “nothingness”. Drawing on the work of the poet and cultural theorist Fred Moten, this article offers a reading of this recent postulation of blackness as “nothingness” in light of some of the similar theoretical endeavors in post-Kantian European philosophy. By comparing Moten’s “paraontological” conception of nothingness to Heidegger’s self-nihilating nothing, Sartre’s relative nothingness, as well as Schelling’s notion of absolute nothingness, this article argues that (...) Moten’s paraontology presents a more robust and systematic conception of nothingness than those of Heidegger, Sartre, and Schelling. By way of this comparison with these “canonical” accounts from European philosophy, this article highlights not only the unique features of Moten’s sophisticated formulation of nothingness, but also some of unacknowledged presumptions and prejudices of traditional metaphysics which Moten’s work calls into question. (shrink)

This study examines thirteenth to twentieth century Tibetan and Mongolian monastic memorializations of the bodily violence enacted upon Köten Ejen at the center of the “Buddhist conversion of the Mongols.” Koten Ejen (Tib. Lha sras go tan rgyal po, 1206–1251) was Chinggis Khan’s grandson and a military leader involved in Mongol campaigns against the Song Dynasty and against Buddhist monasteries in eastern Tibet. In 1240, Koten famously summoned the Central Tibetan Buddhist polymath Sakya Pandita, by then already an old man, (...) to his court at Liangzhou. Examining Tibetan and Mongolian accounts about their meeting from the last seven centuries, this study shows that it was neither compelling philosophy nor some turn of faith that converted the Mongols. It was, rather, Sakya Pandita’s violent therapeutic intervention into the space of Koten’s ill body that wrenched the Mongol body politic into the Dharmic fold. (shrink)

The idea that Buddhism played a key role in the development of New Confucianism has long prevailed in academia, but it is not until recent years that such an idea has been critically studied through a series of monographs, mainly published by Brill. This book is one of the excellent works concerning such an important topic. Unlike other works which focus on the possible influence of specific Buddhist schools on individual New Confucian thinkers, The Awakening of Faith and New Confucian (...) Philosophy stresses the relationship between a specific Buddhist 'classic,' the Treatise on Awakening Mahāyāna Faith or Dasheng qixin lun 大乘起信論, and New Confucianism as a whole. This makes for a very in-depth discussion.Including the... (shrink)

IntroductionDeep brain stimulation (DBS) is increasingly used to treat the symptoms of various neurologic and psychiatric conditions. People can undergo the procedure during reproductive years but the safety of DBS in pregnancy remains relatively unknown given the paucity of published cases. We thus conducted a review of the literature to determine the state of current knowledge about DBS in pregnancy and to determine how eligibility criteria are approached in clinical trials with respect to pregnancy and the potential for pregnancy.MethodsA literature (...) review was conducted in EMBASE to identify articles involving DBS and pregnancy. Two reviewers independently analyzed the articles to confirm inclusion. Data extracted for analysis included conditions treated, complications at all stages of pregnancy, neonatal/pediatric outcomes, and DBS target. A second search was then conducted using www.clinicaltrials.gov. The same two reviewers then assessed whether each trial excluded pregnant individuals, lactating individuals, or persons of childbearing age planning to conceive. Also assessed was whether contraception had to be deemed adequate prior to enrollment.ResultsThe literature search returned 681 articles. Following independent analysis and agreement of two reviewers, 8 pregnancy related DBS articles were included for analysis. These articles described 27 subjects, 29 pregnancies (2 with subsequent pregnancies), and 31 infants (2 twin pregnancies). There was 1 preterm birth at 35 weeks, and 3 patients who experienced discomfort from the DBS battery (i.e., impulse generator) placement site. All 27 patients had a DBS device implanted before they became pregnant, which remained in use throughout their pregnancy. There was exclusion of pregnant individuals from 68% of 135 interventional trials involving DBS. Approximately 44% of these trials excluded persons of childbearing age not on “adequate contraception” or wishing to conceive in the coming years. Finally, 22% excluded breastfeeding persons.ConclusionThe data from 29 pregnancies receiving DBS treatment during pregnancy was not associated with unexpected pregnancy or post-partum complication patterns. Many clinical trials have excluded pregnant individuals. Documentation of outcomes in larger numbers of pregnancies will help clarify the safety profile and will help guide study designs that will safely include pregnant patients. (shrink)

Memory consolidation is the process in which memory traces are strengthened over time for later retrieval. Although some theories hold that consolidation can only occur during sleep, accumulating evidence suggests that brief periods of wakeful rest may also facilitate consolidation. Interestingly, however, Varma and colleagues reported that a demanding 2-back task following encoding produced a similar performance to a wakeful reset condition. We tested whether participants’ recall would be best following a wakeful rest condition as compared to other distractor conditions, (...) consistent with the extant wakeful rest literature, or whether we would replicate the finding by Varma and colleagues such that participants’ memory benefitted from both a rest and a 2-back task following encoding. Across two experiments, we used similar and the same encoding material as used the one by Varma and colleagues, employed a wakeful rest condition adapted for online testing, and compared participants’ recall across post-encoding conditions. In the first experiment, we used a between-subjects design and compared participants’ cued recall performance following a period of wakeful rest, a 2-back task, or a rest + sounds condition. The second experiment more closely replicated the experimental design used by Varma and colleagues using a within-subjects manipulation. Ultimately, our findings more consistently aligned with the canonical wakeful rest finding, such that recall was better following the rest condition than all other post-encoding conditions. These results support the notion that wakeful rest may allow for consolidation by protecting recently encoded information from interference, thereby improving memory performance. (shrink)