Two approaches have emerged to resolve discrepancies between predictions and observations at galactic and cosmological scales: introducing dark matter or modifying the laws of gravity. Practitioners of each approach claim to better satisfy a different explanatory ideal, either unification or simplicity. In this chapter, we take a closer look at the ideals and at the successes of these approaches in achieving them. Not only are these ideals less divisive than assumed, but moreover we argue that the approaches are focusing on (...) different aspects of the same ideal. This realisation opens up the possibility of a more fruitful trading zone between dark matter and modified gravity communities. (shrink)

Alex Worsnip argues that structural rationality is a unified phenomenon, given the constitutive facts about the natures of our mental states. He also argues that structural rationality is normatively significant, given the reasons to which its requirements give rise. This paper breaks bad news: these two parts of Worsnip’s picture are strange bedfellows, since the sequences of states and processes that would clearly count as transgressing the structural-rationality-based reasons that he describes are precisely those sequences that are ruled out by (...) the constitutive facts about our mental states that he also describes. As a result, it is hard to see what transgressing our structural-rationality-based reasons could amount to on Worsnip’s overall picture, and thus hard to see how these reasons could be normative in an interestingly robust way. The present paper spells out this puzzle and then discusses how Worsnip might respond and how far it might generalize. (shrink)

We propose a two-step guessing game to measure the depth of thinking. We apply this method to the P beauty contest game. Using our method, we find that 81% of subjects do not make choice following best response reasoning while the classical method would suggest only 12%. The result suggests that the classical method has the fundamental problem that it cannot distinguish if a submitted number is due to best response reasoning or not. It also suggests that traditional level k (...) analysis falsely attributes some sophistication to random players, and that the degree of false attribution is large. Our procedure provides an alternative way to identify whether the individual has best response reasoning which is essential for any positive level of depth of thinking and differentiates between the depth of thinking and random choice, and hence provides a very different conclusion, which is suggestive of limitations of the classical method. (shrink)

Judgments of character traits tend to be overcorrelated, a bias known as the halo effect. We conducted two studies to test an explanation of the effect based on shared lexical context and connotation. Study 1 tested whether the context similarity of trait names could explain 39 participants’ ratings of the probability that two traits would co-occur. Over 126 trait pairs, cosine similarity between the word2vec vectors of the two words was a reliable predictor of the human judgments of trait co-occurrence (...) probability (cross-validated r2 =.19, p <.001). Two measures related to word similarity increased the variation accounted for in the human judgments to 45%, cross-validated (p <.001). In Experiment 2, 40 different participants judged similarity of word meaning within the pairs, confirming that the word pairs were not simply synonymous (Average [SD] = 40.8/100 [13.1/100]). Shared lexical context and word connotation play a role in shaping the halo effect. (shrink)

Una de las características del cambio científico que ofrece más resistencia a la elaboración de un modelo teórico que permita dar cuenta de él, la constituye su carácter social. Un intento importante para vencer esa resistencia, el realizado por David Hull, se apoya en la noción de adecuación inclus..

Background: We aimed to determine the smallest changes in health-related quality of life (HRQoL) scores in the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire core 30 and the Brain Cancer Module (QLQ-BN20), which could be considered as clinically meaningful in brain cancer patients. Materials and methods: World Health Organisation performance status (PS) and mini-mental state examination (MMSE) were used as clinical anchors appropriate to related subscales to determine the minimal clinically important differences (MCIDs) in HRQoL (...) change scores (range 0-100) in the QLQ-C30 and QLQ-BN20. A threshold of 0.2 standard deviation (SD) (small effect) was used to exclude anchor-based MCID estimates considered too small to inform interpretation. Results: Based on PS, our findings support the following integer estimates of the MCID for improvement and deterioration, respectively: physical (6, 9), role (14, 12), and cognitive functioning (8, 8); global health status (7, 4(star)), fatigue (12, 9), and motor dysfunction (4(star), 5). Anchoring with MMSE, cognitive functioning MCID estimates for improvement and deterioration were (11, 2(star)) and for communication deficit were (9, 7). Estimates with asterisks were <0.2 SD and were excluded from our MCID range of 5-14. Conclusion: These estimates can help clinicians evaluate changes in HRQoL over time, assess the value of a health care intervention and can be useful in determining sample sizes in designing future clinical trials. (shrink)

Four decades after the Baby M case that led to the prohibition of commercial surrogacy in New York, much has changed in the infertility industry. Advanced technologies including the advent of gestational carrier pregnancies had made it easier and more efficient to create IVF embryos at a distance and over time, accelerating a boom in cross-border, reproductive services and allowing compensated surrogacy to flourish in a growing number of surrogacy-friendly states and beyond. For international couples, the USA has become a (...) hot spot for “circumvention tourism” given its first-rate medical care, ample supply of willing gestational carriers, burgeoning interest in family building among gay couples, and immediate USA citizenship for the child. This commentary reviews selected sociocultural and global forces that helped set the stage for the passage of the Child-Parent Security Act in New York state in 2021, and the efforts by its opponents for stronger protections not only for gestational carriers, but for gamete donors and the donor-conceived offspring. I argue that despite more responsive medical and legal guidelines, the high market demand and economic profits, combined with the lack of regulatory teeth, faulty assumptions about health risks and decision-making autonomy, and inadequate research on long-term health outcomes, continue to make compensated gestational surrogacy in the state of New York a high-risk venture without adequate informed consent. Possible unintended consequences and future research questions are proposed. (shrink)

Limitations on reproductive decision making, including forced sterilization and involuntary birth control, raise significant ethical challenges. In the United States, these issues are further complicated by a disturbing history of the abuse and victimization of vulnerable populations. One particularly fraught challenge is the risk of teratogenicity posed by moodstabilizing psychiatric medications in patients who are incapable of appreciating such dangers. Long-acting reversible contraception (LARC) offers an intervention to prevent pregnancy among individuals who receive such treatments, but at a cost to (...) their reproductive autonomy. This article examines the ethical issues involved in the use of involuntary LARC for patients on teratogenic psychiatric medications (TPMs) and argues that such an approach can only be justified as a last resort after a careful consideration of the alternatives and an assessment of potential risks and benefits. (shrink)

This paper discusses a novel problem at the intersection of ethics and epistemology: there can be cases in which moral considerations seem to "encroach'' upon belief from multiple directions at once, and possibly to varying degrees, thereby leaving their overall effect on belief unclear. We introduce these cases -- cases of moral encroachment under moral uncertainty -- and show that they pose a problem for all predominant accounts of moral encroachment. We then address the problem, by developing a modular Bayesian (...) framework that, we argue, is sufficiently flexible and scaleable to accommodate the multifaceted uncertainty we describe while still generating clear recommendations for an agent's beliefs. Our framework has several practical upshots, and we close by articulating them: we derive insights about the relationship between moral character and doxastic behavior and make suggestions for how to encourage people to revise their doxastic states in morally laudable ways, without deviating from core Bayesian norms. (shrink)

The investigator seeks guidance related to a planned recruitment strategy of requiring participants to live within close proximity to the study site for the 32-week Phase II study examining the saf...

Table 3 was incomplete in the initial online publication. The original article has been corrected.

Fashion has a varied and explosive history. Our responsibility as educators preparing students and therefore careers for this context places us in a very difficult and complex position. Do we prepa...

This article examines the existentialist meanings of “trouble,” an experience that recurs throughout Simone de Beauvoir’s and Jean-Paul Sartre’s writings on sadism, love, and desire. For both authors, trouble represents the phenomenological experience of being submerged in one’s body through either extreme pleasure or pain. Whereas Sartre’s use of trouble ends up denying intersubjective connection, Beauvoir’s writings leave open the possibility for reciprocity, but only if we are able to create the social grounds on which trouble can flourish.

We shall argue that there is adequate moral justification for capital punishment with linkage, that is, with linkage to keeping non-murderers from dying. We present the argument with two aims in mind. The first is to question the conventional wisdom, seldom challenged even by proponents of capital punishment, that being an abolitionist is closely connected to having a civilized respect for human life. This conventional wisdom, we hope to show, is somewhat off the mark. To this end we exhibit structural (...) similarities between so-called lifeboat dilemmas and the public's relationship to a murderer. In a lifeboat dilemma one must choose between saving this life or that, since the lifeboat will not hold both persons. Now if this life were an innocent's and that one a murderer's, a choice to save the latter would not be met with accusations of callousness towards human life. We hope to project everyone's intuitions about this case onto the more baffling case of a society's relationship to the murderers and dying innocents in its midst. (shrink)

One of my favorite bioethics quotes is nearing 50 years old:Let us not forget that progress is an optional goal, not an unconditional commitment, and that its tempo in particular, compulsive as it may become, has nothing sacred about it. Let us also remember that a slower progress in the conquest of disease would not threaten society, grievous as it is to those who have to deplore that their particular disease be not yet conquered, but that society would indeed be (...) threatened by the erosion of those moral values whose loss, possibly caused by too ruthless a pursuit of scientific progress, would make its most dazzling triumphs not worth having.Despite its age, this invocation seems to me increasingly relevant as time... (shrink)

The concept of ‘neurodiversity’ to speak of conditions such as autism, dyslexia, and others as differences, not disorders or pathologies, relies on a robust account of human flourishing that can incorporate these conditions. Conceptions of illness and well-being are always partially theological, whilst also having to be grounded in the empirical realities of the present time. Therefore, positive developmental psychology is a particularly apt field for developing a theology-informed psychology. This article argues that recent work in theology-engaged psychology of thriving, (...) as opposed to subjective flourishing, is the best approach to securing a vision of well-being for neurodiverse persons. (shrink)

Die ATB ist die traditionsreichste Editionsreihe der germanistischen Mediävistik. Begründet 1881 von Hermann Paul, wurde sie von führenden Fachvertretern, Georg Baesecke, Hugo Kuhn, Burghart Wachinger, betreut. Seit 2001 liegt die Verantwortung in den Händen von Christian Kiening. Die mittlerweile etwa 120 Bände verknüpfen exemplarisch Handschriftennähe und Lesbarkeit, wissenschaftliche Arbeit am Text und Blick auf die akademische Lehre. Sie umfassen anerkannte, zum Teil kommentierte Ausgaben 'klassischer' Autoren der Zeit um 1200, aber auch veritable Werkausgaben (Notker der Deutsche) und anspruchsvolle Neueditionen (Eckenlied, (...) Heinrich von dem Türlin). (shrink)

This essay considers the potential role of bioethics in disaster response planning and preparedness. Bioethicists can make substantial contributions, by ensuring that decision-making and distribution of resources during crises is carried out in a fair and just manner, as well as by examining the assumptions upon which disaster planning are based. Bioethicists should also be aware of potential pitfalls of overly-hasty engagement with this new field.

Laland et al.'s bidirectional model is a welcome starting point that can be enhanced by a full incorporation of systems thinking into its framework. Systems thinkers note that culture is not transmitted linearly in chunks but is co-constructed within subgroups. Niche construction, particularly among primates, should be studied primarily through the effects that social relationships have on selection pressures.

Susan James, in her recent work Passion and Action: The Emotions in Seventeenth-Century Philosophy (Oxford: Clarendon 1997), prefaces her investigation of emotions in the seventeenth century with a series of remarks about the earlier career of the emotions, in particular their treatment in the Middle Ages. In brief, she takes the ‘new’ analyses of the passions put forward in the seventeenth century to be a philosophical sideshow to the main event: the dethronement of Aristotelian natural philosophy and metaphysics (22). She (...) describes the consequences for psychology as follows.. (shrink)