Insight into animal biology and development provided by classical genetic analysis of the model organism Drosophila melanogaster was an incentive to develop advanced genetic tools for this insect. But genetic systems for the over one million other known insect species are largely undeveloped. With increasing information about insect genomes resulting from next generation sequencing, RNA interference is now the method of choice for reverse genetics, although it is constrained by the means of delivery of interfering RNA. A recent advance to (...) ensure sustained delivery with minimal experimental intervention or trauma to the insect is to exploit commensal bacteria for symbiont‐mediated RNA interference. This technology not only offers an efficient means for RNA interference in insects in laboratory conditions, but also has potential for use in the control of human disease vectors, agricultural pests and pathogens of beneficial insects. (shrink)

Compiles the photographs taken by Leonard Freed of the 1963 March on Washington for Jobs and Freedom, during which Dr. Martin Luther King Jr. delivered his "I Have a Dream" speech.

“Tell me," Wittgenstein once asked a friend, "why do people always say, it was natural for man to assume that the sun went round the earth rather than that the earth was rotating?" His friend replied, "Well, obviously because it just looks as though the Sun is going round the Earth." Wittgenstein replied, "Well, what would it have looked like if it had looked as though the Earth was rotating?” What would it have looked like if we looked at all (...) sciences from the viewpoint of Wittgenstein’s philosophy? Wittgenstein is undoubtedly one of the most influential philosophers of the twentieth century. His complex body of work has been analysed by numerous scholars, from mathematicians and physicists, to philosophers, linguists, and beyond. This volume brings together some of his central perspectives as applied to the modern sciences and studies the influence they may have on the thought processes underlying science and on the world view it engenders. The contributions stem from leading scholars in philosophy, mathematics, physics, economics, psychology and human sciences; all of them have written in an accessible style that demands little specialist knowledge, whilst clearly portraying and discussing the deep issues at hand. (shrink)

This book is a record of my dialogues with Stephen Hawking, his graduate assistants and his nurses during a four city public lecture tour I organized for Hawking, including Portland, Eugene, Seattle, Vancouver, BC. We discussed 20th century science and philosophy of science. Since I was often the one being questioned, much of the contents reflect my PhD research at the University of London. My focus was on understanding the limits of science, as represented by quantum theory and relativity. My (...) mentors had been Paul Feyerabend and Imre Lakatos, and I was strongly influenced by Karl Popper and Thomas Kuhn. In one in depth presentation to Hawking I suggested that Newtonian space-time and Maxwellian space-time were complementary, were defined by complementary symmetry principles. I had opportunity to present the same arguments to Kip Thorne and Freeman Dyson. Hawking simply remarked that I 'may be right'. Thorne confirmed that practitioners of General Relativity use both depending on the problem at hand. Dyson was emphatic – "Yes. Definitely. Absolutely.". (shrink)

Decision theory aims at a general account of rationality covering humans but to begin makes idealizations about decision problems and agents' resources and circumstances. It treats inerrant agents with unlimited cognitive power facing tractable decision problems. This book systematically rolls back idealizations and without loss of precision treats errant agents with limited cognitive abilities facing decision problems without a stable top option. It recommends choices that maximize utility using quantizations of beliefs and desires in cases where probabilities and utilities are (...) indeterminate and using higher-order utility analysis in cases of limited access to probabilities and utilities. For agents burdened with mistakes, it advocates reasonable attempts to correct unacceptable mistakes before deciding. In decision problems without a stable top option, a topic of game theory, it proposes maximizing self-conditional utility among self-supporting options. In games of strategy, the new principles lead to solutions that are Pareto optimal among equilibria composed of jointly self-supporting strategies. Offering an account of bounded rationality, the bookmakes large strides toward realism in decision theory. (shrink)

How do we think about the worlds we live in? The formation of categories of events and objects seems to be a fundamental orientation procedure. Facet theory and its main tool, the mapping sentence, deal with categories of behavior and experience, their interrelationship, and their unification as our worldviews. In this book Hackett reviews philosophical writing along with neuroscientific research and information form other disciplines to provide a context for facet theory and the qualitative developments in this approach. With a (...) variety of examples, the author proposes mapping sentences as a new way of understanding and defining complex behavior. (shrink)

The constantly accelerating progress of contemporary natural science is indissolubly associated with the development and use of mathematics and with the processes of mathematical modeling of the phenomena of nature. The essence of this diverse and highly fertile interaction of mathematics and natural science and the dialectics of this interaction can only be disclosed through analysis of the nature of theoretical notions in general. Today, above all in the ranks of materialistically minded researchers, it is generally accepted that theory possesses (...) a value of its own. Contrary to positivist concepts of the nature of our knowledge, the meaning and significance of theory do not consist merely of the recording of experimental data, their classification and notation in abbreviated form. The meaning of theory is considerably more significant and is revealed, above all, in its explanatory and predictive functions. Contemporary theoretical knowledge is quite advanced and comprises a highly complex system, relatively self-contained and capable of internal development. Mathematics is the most interesting and distinctive phenomenon in the system of theoretical knowledge, in the system of science in general. It is in its dialectical development that the internal force and dynamics of the development of theory, in the very broadest sense of that word, find expression. Paul Lafargue tells us that Karl Marx held that "science only attains perfection when it succeeds in making use of mathematics" . In many fields of research the formulation of new ideas and concepts rests upon mathematics, its concepts and notions, and "is suggested" by the latter. "Mathematics," writes F. Dyson, "is the main source of the notions and principles out of which new theories are created" . The basic significance of mathematics to theory has been noted by outstanding thinkers over the course of the entire history of development of science. Today the expressive phrase, "the mathematization of knowledge," has come into general currency as a description of the principal direction of growth of theoretical notions in natural science. However, with respect to the growth of modern theoretical physics in general, the statement that it develops primarily by the method of the mathematical hypothesis has general validity. For example, the principal findings and discoveries of quantum theory and particle physics, starting from the corpuscularwave dualism and terminating with the omega minus hyperon and hypothetical quarks, were obtained or made "at the tip of a mathematician's pen.". (shrink)

This is the text of The Lindley Lecture for 1969, given by Paul Edwards, an Austrian-American philosopher.

General information -- The animals themselves -- Philosophical arguments -- Laws -- Political realities -- Social realities -- Education and the arts -- Contemporary sciences -- Major figures and organizations in the animal rights movement -- The future of animal rights.

pGiven the long-standing and deeply rooted intertwinement between reason and philosophy, there is a pressing need to reappraise our operative conceptions of rationality and critical inquiry in the wake of the transition from foundationalism to postfoundationalism.nbsp; For while opening up exciting new vistas, this transition poses perplexing problems regarding how we might go about justifying our knowledge claims without the possibility of recourse to incontrovertible foundations, indubitable starting points, or algorithmic procedures.nbsp; The challenge is all the more acute given that (...) the turn to language and intersubjectivity that characterises this transition has fostered the proliferation of a diversity of competing and allegedly self-validating worldviews, that render the encounter with difference an indispensable feature of the contemporary epistemological landscape while reinforcing the threat of relativism and groundlessness./ppThrough engaging with the work of Juuml;rgen Habermas, Hans-Georg Gadamer and Michel Foucault, three theorists widely recognized as major contributors to the contemporary debate, the present paper responds to these problems by seeking to delineate the constitutive features of a dialogically-oriented conception of rationality and critical inquiry capable of meeting postfoundationalist needs.nbsp; In the process, it reinforces the advantages of the reading these theorists as complementary rather than as oppositional, as has typically been the case./p. (shrink)

Modeling involves the use of false idealizations, yet there is typically a belief or hope that modeling somehow manages to deliver true information about the world. The paper discusses one possible way of reconciling truth and falsehood in modeling. The key trick is to relocate truth claims by reinterpreting an apparently false idealizing assumption in order to make clear what possibly true assertion is intended when using it. These include interpretations in terms of negligibility, applicability, tractability, early-step, and more. Elaborations (...) are suggested about their precise formulations, mutual relationships, and truth-aptness. (shrink)

Case (a) has been familiar for a long time, and is supported by a fair amount of historical evidence (Kiparsky 1968, 1973). It was adopted by NGG (Vennemann 1972, Hooper 1976) and by Natural Phonology (Stampe 1972/1980). Prince & Smolensky 1993 dub it lexicon optimization, and show that it is a consequence of basic assumptions of OT.

Utilizing 100 key readings, The Political Theory Reader explores the rich tradition of ideas that shape the way we live and the great issues in political theory ...

In lieu of an abstract, here is a brief excerpt of the content:Comme Elle Respire:Memory of Breath, Breath of MemoryFrédérique Berthet (bio)Translated by David F. Bell (bio)La poésie est un système de respiration, c'est fait pour mieux respirer.[Poetry is a respiration system, it's made for breathing better.]—Erri De Luca- Stop!- What?- I can hear you breathing!...- Stop!- Breathing?- Yes!—Paul Thomas AndersonLittle paper-fish cutouts have been placed on the ground, on the carpet.We're in the reassuring '70s stylishness of a doctor's (...) office. The carpet is soft and glistens like in interior decoration magazines, it's with it, in. We couldn't care less about what Dyson vacuum cleaners and "purifiers" boast they can eliminate several decades later: acarids, those microscopic domestic arthropods, human parasites (notably), and airborne vectors of infectious disease (colds, coughs, respiratory distress). No, in the spring of 1975, innocently and self-satisfyingly, the urbane doctor flaunts the opulent carpet with curly pile in his luxury apartment with its state-of-the-art waiting room.In this grand interior of a medical office, a man in a white coat plies his important trade. For example, that day a little girl is re-learning how to breathe. One might think that exhaling and inhaling is learned for life—je t'aime comme je respire, elle parle comme elle respire, il ment comme il respire1—from the very first cry at birth. But in fact, sometimes in life breathing gets stuck between the nasal cavity and the bronchial tubes, between the respiratory tract and the lungs. Progressively, imperceptibly, the organism is short of air, a malicious infection spreads and impairs [End Page 92] alveolar diffusion to the point of respiratory exhaustion: Is it serious, doctor? We must act quickly, very quickly. How to liquify what stopped up the system one day to the point of blocking it—the doctors know what to do.This doctor undertook long, arduous and learned studies. He knows functionally how a living being breathes, how a child lives organically. He can also re-teach the little girl what she no longer knows how to do: inhale, exhale using the full volume of the thoracic cage, regulating the ventilatory flow, solidifying the invisible membranes. In the child's family, everyone knows (and knows how to do) important things, but no one undertook extensive studies, much less studies of the aerial exchanges in the human body. This special knowledge possessed by the doctor (unless special means something else unspoken that would explain why this specific doctor was chosen rather than any other) surrounds him with a padding of respect that creates (and the little girl feels this) a sort of protective continuum between him and the walls within which he sees her, where he practices his kind of calm and slow urbane medicine. It's far from the formidable hospital she has just left, with its spherical apparatus next to the bed aspirating the red and yellow pleural liquid, the "treatment room" where the surgeon, the "butcher" as the nurses call him among themselves, manipulated the drain without anesthesia, with no regard for the child's suffering. The doctor, and his place in the elevated tower, even though they are not to be confused, make for a cozy reception space in which one is comfortable, even in passing.This doctor—who is, in truth, a massage-physiotherapist—is located in a designer high-rise building with a façade decorated by white, pointed features that manifest a will toward an architectural act. On the ground floor, the entrance hall is finished in dark-veined, clear brown marble, and the entry threshold between the exterior and interior is marked by large transparent glass panes that must be manipulated with care. The entrance hall has an intimidating sonority and a useless cold nudity from which one escapes in an elevator where one is surrounded by mirrors and gold buttons and in which one speeds upward silently toward floors, clouds.The designer high-rise is located at the outskirts, the outskirts of a city of recent Olympic stature, where several years earlier Olympic athletes were welcomed and trained to increase their respiratory capacity and... (shrink)

Schelling's Philosophy of History Paul Collins HAYNER. CHAPTER TWO THE ROLE OF HISTORY IN SCHELLING'S PHILOSOPHY TO 1809 I. SCHELLING AS DlSCIPLE OF FlCHTE The earliest philosophical expressions of Friedrich Wilhelm ...

This book is the authorized political biography of Kenneth Waltz. The theoretical work of Kenneth Neal Waltz (June 8, 1924 - May 12, 2013) during the last half of the twentieth century in international relations theory is known by virtually everyone in this scholarly field. He is among the few likely still to be cited in the last half of the twenty-first century. Then, as now, he no doubt has followers within the realist camp who see him as an earlier (...) luminary as well as his critics drawn to the lightning-rod quality of his work. Paul Viotti identifies the intellectual sources and experiences leading to the ideas that underlie Waltz's theoretical work. Viotti has been granted unfettered access to Waltz's files at Columbia, in his residences in Manhattan and Maine, and in archives at Oberlin, and uses these documents to paint a thorough, insightful biography bolstered by some of Waltz's previously-unexplored work. Through a series of interviews with Waltz about his life-starting with his German great-grandparents' immigration to the US in the 19th century-this biography produces personal insights into the development of his theoretical and policy-based contributions. (shrink)

Like relativity and quantum theory chaos research is another prominent concept of 20th century physics that has triggered deep and far-reaching discussions in the philosophy of science. In this volume outstanding scientists discuss the fundamental problems of the concepts of law and of prediction. They present their views in their contributions to this volume, but they also are exposed to criticism in transcriptions of recordings made during discussions and in comments on their views also published in this book. Although all (...) authors assume familiarity with some background in physics they also address the philosophers of science and even a general audience interested in modern science's contribution to a deeper understanding of reality. (shrink)

_The Soft Edge_ is a one-of-a-kind history of the information revolution. In his lucid and direct style, Paul Levinson, historian and philosopher of media and communications, gives us more than just a history of information technologies. _The Soft Edge_ is a book about theories on the evolution of technology, the effects that human choice has on this evolution, and what's in store for us in the future. Paul Levinson's engaging voice guides us on a tour that explains how (...) communications media have been responsible for major developments in history and for profound changes in our day-to-day lives. Levinson presents the intriguing argument that technology actually becomes more human. We see how information technologies are selected on the basis of how well they meet human needs. Why is email more like speech than print is? Why didn't the arrival of television destroy the radio? These and many more thought provoking questions are answered in _The Soft Edge_. Boldly extending and deepening the pathways blazed by McLuhan, Paul Levinson has provided us with a brilliant and exciting study of life with our old media, our new media, and the media still to come. (shrink)

Paul Thom argues that opera is a set of practices framed by the concepts of work, interpretation, performance, and art. His argument is that operatic works have the potential to be art, but so do operatic productions, independently of their value as interpretations of the works they stage.

Dans cet ouvrage, Paul Franceschi propose une méthode novatrice pour aborder et résoudre les conflits de valeurs. Il guide pas-à-pas le lecteur à travers l’analyse de nombreuses situations, représentatives des types de conflits de valeurs les plus courants. Il présente des stratégies adaptées, issues de l'analyse logique de ces situations. Chaque cas est exploré en détail, avec des exemples tirés de la vie quotidienne, d’événements historiques et de la littérature mondiale. Rédigé dans un style clair et accessible, ce livre (...) ne nécessite aucune connaissance préalable. Il est enrichi de nombreux diagrammes et illustrations qui facilitent la compréhension des différentes notions et offrent un éclairage structuré sur les dynamiques conflictuelles. Un guide utile pour mieux appréhender les complexités des valeurs humaines et développer vos compétences en matière de résolution de conflits. (shrink)

Alien Politics retrieves from the writings of Marx an original theory of the state which remains viable and relevant today. Paul Thomas traces the process by which Marx's theory of the state as the instrument of the capitalist ruling class became transformed into communist dogma under the auspices of Lenin and other "official" Marxist stalwarts. He argues that Marx's writings still have something to teach us and should not be pulled down with the monoliths and mausoleums of communism. The (...) book continues the work of "Western Marxist" thinkers such as Antonio Gramsci and Nicos Poulantzas who came to understand the modern state in terms different from the rightly-discredited "ruling class" theory of the state associated with Leninism. Such Western Marxist theorists--more careful and nuanced readers of Marx than their powerfully-placed antagonists--helped formulate a theory of what Thomas calls "alien politics." The theory of alien politics, originally elaborated by Marx in his early critiques of Hegel and the Young Hegelians, diverges from ruling class state theory because it counterposes the state against civil society rather than treating it as an epiphenomenon of civil society. Unlike ruling class theory, alien politics retains considerable relevance as a critique of state forms that still exist in the West as well as those that have collapsed in the East. This topical and groundbreaking book re-interprets Marx and demonstrates how his ideas remain critical for political theorists, social scientists and anyone interested in the modern state. (shrink)

Like _Beyond All Appearances_,_ _which it supplements, Paul Weiss’s new book is a fundamental work which faces all the hard issues which are not only at the heart of philosophy but at the core of our entire culture. Readers of Mr. Weiss’s phenomenology of religion will need no introduction to this new work which expands and clari­fies many of the issues raised in _Beyond All Appearances. _However, no knowl­edge of Paul Weiss’s previous books is required to understand and (...) appreciate this brilliant new exposition. Weiss’s plain style makes his ideas accessible to all intelligent readers, whether or not they have been trained as professional philosophers. Here in _First Considerations _Mr. Weiss addresses himself to such topics as actuality, internalization, evidence, names, substance, being, natures and possibilities, existence, unity and the cosmos—issues which have engrossed him as a moral philosopher and meta­physician throughout his distinguished career. In his progress through the ideas and issues expounded in this new book Mr. Weiss is concerned with the human condition distinctive of this species of ours. Rigorously applied, his moral philosophy is as complete and thorough as that of any of the major thinkers, and provides as complete a guide as, for example, that of Buddhism. A highly original work, no doubt well in advance of current trends in philosophy, _First Considerations _will provoke further thought and discussion and will be regarded as a seminal work in modern philosophical approaches. (shrink)

In this new interpretation of Plato's Phaedo, Paul Stern considers the dialogue as an invaluable source for understanding the distinctive character of Socratic rationalism. First, he demonstrates, contrary to the charge of such thinkers as Nietzsche, Heidegger, and Rorty, that Socrates' rationalism does not rest on the dogmatic presumption of the rationality of nature. Second, he shows that the distinctively Socratic mode of philosophizing is formulated precisely with a view to vindicating the philosophic life in the face of these (...) uncertainties. And finally, he argues that this vindication results in a mode of inquiry that finds its ground in a clear understanding of the problematical but enduring human situation. Stern concludes that Socratic rationalism, aware as it is of the limits of reason, still provides a nondogmatic and nonarbitrary basis for human understanding. (shrink)

Here are Holsteins as they've rarely been depicted before—abstractions in black and white, artist's models with long-lashed liquid eyes, soulful individuals and sisters of the herd, the fecund embodiments of mother's milk, tenants of the land, spirits and myths. Fine art photographer Paul Thoresen captures the very essence of cows with his camera. He has been artfully photographing Holstein cattle for more than five decades, mostly on three family farms within a mile of his home near Paoli, Wisconsin. Cows: (...) A Closer Look contains more than seventy photographs in both black-and-white and color. (shrink)

In this fifth volume of _Philosophy in Process _Paul Weiss presses further his search for “breakthroughs in insight,” as his reflections take him deeper into a consideration of the full nature of actualities, the problem of death, an analysis of logic, and a consideration of a theory of the future. Like its predecessors in the series, the present volume consists of journal entries which, in this instance, cover the months from September 1965_ _through August 1968,_ _a period which saw published (...) Mr. Weiss’s _The Making of Men_,_ _as well as volumes 3_ _and 4_ _of _Philosophy in Process_,_ _and the writing and preparation for publication of _Sport: A Philosophic Inquiry. _These and other books of Mr. Weiss are discussed by him in his journals. Volume 5_ _is especially rich in providing review of and reflection on his own work. (shrink)