This study investigates the complex relationship between the physical and digital spaces of the city of Douala, Cameroon by comparing its online representation with the social representations emerging orally by locals. Using the results of two existing studies reporting on the online image of the city, we investigate the social representations foreigners and locally relevant people have of Douala and uncover similarities and discrepancies of the two resulting representations. Outcomes from the analysis permit reflection on the implications of these and (...) show an unripe, intermediate stage of the “hybrid Douala,” where the virtual space seems still not to be affecting the way the physical space is experienced, as well as where the gaps in the digital divide are perpetuated. At the same time, strong local ownership of certain digital activities suggests how the online image of the city is in the process of being constructed and developed locally. As the spaces of the city start appearing online, the process of hybridization between physical and digital Douala is slowly taking place and offline and online narratives, now rather separated, will possibly communicate a different image of the city to global online narratives. (shrink)

The concept of ethical preparedness (EP), defined as a set of practices in genomic medicine aimed not only at efficiently managing sensitive issues in the laboratory but also at ensuring adherence to ethical principles,1 has potential benefits for clinical laboratory scientists, contingent on three key conditions. First, fostering cooperation and mutual support between commercial and non-commercial laboratories in cases involving moral dilemmas or the uncertain nature of variants identified in the laboratory is crucial for establishing the best practices in genomic (...) medicine. Medical codes emphasise regulations aimed at maintaining the authority of colleagues and avoiding patient and family misunderstandings, as well as promoting a culture of mutual trust and support within the medical profession.2 Such practices among laboratories would benefit both patients/clients and scientists. The important thing is to recognise that while laboratory results may possess prospective value for future generations, genomic medicine addresses the clinical needs …. (shrink)

In this volume, we have chosen to highlight the importance of education to human rights by reprinting two articles written by Paulo Freire in 1970 for the _Harvard Educational Review_. These articles contain many of Freire's original ideas on human rights and education—issues that are central to his work. Freire was a pioneer in promoting the universal right to education and literacy as part of a commitment to people's struggle against oppression. As Jerome Bruner recognized after Freire's death in May (...) 1997, Freire left as a legacy his commitment to basic human rights: "He was a brave man as well as a far-sighted one. He made us aware of our mindless cruelties, and now the challenge to all of us is to do something about those cruelties.". (shrink)

Drosophila flies began to be used in the study of species evolution during the late 1930s. The geneticists Natasha Sivertzeva-Dobzhansky and Elizabeth Reed pioneered this work in the United States, and María Monclús conducted similar studies in Spain. The research they carried out with their husbands enabled Drosophila population genetics to take off and reveals a genealogy of women geneticists grounded in mutual inspiration. Their work also shows that women were present in population genetics from the beginning, although their contributions (...) have previously remained unacknowledged. The similarities between their research biographies also illustrate their position in a genealogy of partnerships working on Drosophila genetics. (shrink)

This study compares Australian marketers with those in the United States along lines that are particular to the study of ethics. The test measured two different moral philosophies, idealism and relativism, and compared perceptions of ethical problems, ethical intentions, and corporate ethical values. According to Hofstede''s cultural typologies, there should be little difference between American and Australian marketers, but the study did find significant differences. Australians tended to be more idealistic and more relativistic than Americans and the other results were (...) mixed, making it difficult to generalize about the effects of moral philosophies on the components of ethical decision-making measured here. This is an important finding; as firms become increasingly more globalized, marketers will more often be involved in cross-cultural ethical dilemmas and it seems natural to assume that similar cultures will have similar ethical orientations. That assumption may well prove erroneous. (shrink)

The nature of blame is not to be identified solely with a judgment, or an overt act, or an angry emotion. Instead, blame should be identified with a sentiment: more specifically, a multi-track disposition that manifests itself in various different emotions, thoughts or actions in a range of different circumstances. This paper aims to argue for these two claims. I start by arguing that blame is not solely a judgment, overt act, or an angry emotion. Then I develop the view (...) that blame is a sentiment. In doing so, I also show how viewing blame as a sentiment avoids objections that justifies us in dismissing the previous accounts. In addition, I argue that it significantly affects other inquiries concerning blame. I end by answering a skeptical challenge that there cannot be an illuminating and unifying analysis of blame. (shrink)

The mental simulation of past and future scenarios allows individuals to understand the past, make predictions about the future, plan and regulate their behavior. A great deal of research has focus...

This paper considers a host of definitions and labels attached to the concept of smart cities to identify four dimensions that ground a review of ethical concerns emerging from the current debate. These are: network infrastructure, with the corresponding concerns of control, surveillance, and data privacy and ownership; post-political governance, embodied in the tensions between public and private decision-making and cities as post-political entities; social inclusion, expressed in the aspects of citizen participation and inclusion, and inequality and discrimination; and sustainability, (...) with a specific focus on the environment as an element to protect but also as a strategic element for the future. Given the persisting disagreements around the definition of a smart city, the article identifies in these four dimensions a more stable reference framework within which ethical concerns can be clustered and discussed. Identifying these dimensions makes possible a review of the ethical implications of smart cities that is transversal to their different types and resilient towards the unsettled debate over their definition. (shrink)

Inclusive education guides democratic schools that advocate for justice and equity, especially for those students with different needs. In this manuscript, the Making Socially Accepting Inclusive Classrooms model and peer mediation are reviewed as the most effective procedures for this purpose.

Durante siglos lo que era un hecho que daba consistencia a la vida humana –cuidar– ha parecido ser sistemáticamente descatalogado y descargado de todo rango y categoría ética. La profusa presencia del cuidado en las fuentes griegas de la antigüedad desde la palabra epiméleia nos ha obligado a profundizar en los sentidos que la cura latina posee en la obra de Santo Tomás dada la preeminencia de esta para la teología moral posterior vinculada a la d– en el catálogo de (...) las virtudes junto con la misericordia, la beneficencia y la limosna que hacen operativa la caridad. El cuidar en su realización del amor irá más allá de socorrer las necesidades cuya forma verbal subvenio oscureció la cura y su sentido de atención, preocupación y ocupación activa por el prójimo.For centuries, what gave consistency to human life –to take care of- has seemed to be systematically discontinued and discharged of all rank and its ethical category. The abundant presence of care in the Greek sources of antiquity since the word epimeleia, has forced us to go deeper into the different meanings that the Latin word cura has in St Thomas’ work, given its prominence in a subsequent moral theology linked to charity. This requires a careful review of care as a virtue - to give it the majority of age- in the catalog of virtues together with mercy, beneficence and alms that make charity operational. Caring, in their realization of love, will go beyond needs help whose verbal form subvenio obscured its meaning of attention, concern and active occupation for the neighbor. (shrink)

Plato's Republic VII suggests that if we ask someone to philosophize when they are too young, they can become corrupted (537e–539d). Republic VII also suggests that to avoid this corruption, we must not expose youth to argument (539a–b). This is not a reasonable option outside of Kallipolis, so a question arises: does Plato describe how to correct corruption if we do not manage to prevent it? This paper shows that a parallel between this passage from Republic VII and a passage (...) from Laws X suggests that he does. Laws X describes an impious man who is corrupted in the same way as the youth exposed to philosophy prematurely in Republic VII. While we leave the youth to his corruption in Republic, the impious man is helped to overcome his corruption in Laws with a refutation followed by a myth (also called a charm). This paper analyses these steps in terms of Plato's psychology, showing that both corruption and correction require a destabilization of the soul, which in these passages is brought about through refutation. This destabilization allows for a reconfiguration, which, with something that can restabilize the soul (for example with myth), can be a reconfiguration for the better. (shrink)

¿Qué tenemos en común y qué nos separa de los animales? ¿Somos un animal más? Las humanidades clásicas, basadas en el excepcionalismo humano, han dado paso a las posthumanidades, que incluyen los estudios animales, así como otras perspectivas que desafían la noción tradicional del sujeto humano, como los estudios de género, poscoloniales y decoloniales, la ecocrítica o la teoría queer. Pensarnos en nuestra relación con los animales tiene consecuencias filosóficas en ámbitos como la ciencia, los afectos, el trabajo y el (...) desarrollo de políticas concretas de salud y de alimentación; todas ellas, zonas de contacto entre humanos y animales. Sobre estos encuentros, aunque nunca reparemos en ello, edificamos nuestro mundo. Este ensayo imprescindible aglutina parte de los conocimientos desarrollados hasta ahora por quienes se han acercado a la relación humano-animal, y los vincula con la historia, los movimientos políticos y sociales, las nuevas concepciones del género, de la ciencia y del conocimiento. Los argumentos, contradicciones, contextos e incluso tabúes que acoge este debate interdisciplinar ayudan a imaginar y a matizar unos presupuestos éticos posibles sobre los que replantear nuestra relación con los animales y, en último término, con nosotros mismos. [Resumen del editor]. (shrink)

While in Europe the debate over clinical ethics consultants’ expertise and professionalization is ongoing, in France it remains rather marginal. In this article, we illustrate how the “commitment model” adopted by the Clinical Ethics Center of the Greater Paris University Hospitals situates itself in such a debate. We first present the commitment model by drawing upon an emblematic case of consultation, and then describe, in turn, its understandings of democratic expertise and of the professionalization of clinical ethics consultation. Accordingly, the (...) commitment model advocates against individual consultants’ certification, but it does not rule out the need for training nor a certain form of professionalization of clinical ethics consultation services. (shrink)

In this paper I discuss whether there is a specific experience of thinking or not. I address this question by analysing if it is possible to reduce the phenomenal character of thinking to the phenomenal character of sensory experiences. My purpose is to defend that there is a specific phenomenality for at least some thinking mental states. I present Husserl's theory of intentionality in the Logical Investigations as a way to defend this claim and I consider its assumptions. Then I (...) present the case of understanding as a paradigmatic case for the phenomenal contrast argument and I defend it against two objections. (shrink)

Several studies have highlighted that reading comprehension is determined by different linguistic skills: semantics, syntax, and morphology, in addition to one’s own competence in reading fluency. On the other hand, according to the Linguistic Interdependence Hypothesis, linguistic skills developed in one’s own native language facilitate the development of these skills in a second one. In this study, we wanted to explore the linguistic abilities that determine reading comprehension in Spanish and in English in Secondary Education students. To do this, 73 (...) Secondary Education Students participated in this study. The students carried out a battery of tasks in English and Spanish, all of them related to reading comprehension and different linguistic skills, which included syntactic awareness tasks, synonymy judgment tasks, and morphological awareness tasks. The results indicated a positive correlation between linguistic competencies in both languages, which were determined by school year, with a lower performance in the 1st year than in the 3rd year. Moreover, we found more skills with correlations in English reading comprehension than in Spanish. Finally, reading comprehension in L1 was mainly explained English reading comprehension, while English reading comprehension was predicted by grade, and syntactic awareness, as well as Spanish reading comprehension. This could be explained by the different levels of exposure to L1 and L2 of sample subjects, as the linguistic variables have different influences on the reading comprehension of both languages. (shrink)

In Spain, the state of alarm declared on March 14, 2020 caused changes in the population in relation to the habits of physical activity and sports practice. This study analyzed what motivational variables predicted the self-efficacy and commitment to sports practice, as well as the differences according to gender, during lockdown and the progressive de-escalation caused by COVID-19, using the theory of self-determination as a theoretical framework. The study sample was conformed of 179 subjects between 18 and 65 years of (...) age. The Behavioral Regulation in Sport Questionnaire, the Psychological Need Satisfaction in Exercise Scale, the Physical Activity Self-Efficacy scale, and the Sport Commitment scale were applied. The most relevant results have showed significant differences in favor of the male gender in terms of levels of controlled motivation and amotivation, as well as higher levels of self-efficacy and basic psychological need of autonomy. Furthermore, the regression analysis has revealed that self-efficacy and current commitment to sports practice were explained by a variance of 57 and 64%, respectively, due to autonomous motivation and the basic psychological need of competence. Therefore, the basic psychological need of competence should be fostered in order to increase the levels of self-determined motivation, self-efficacy, and commitment to sports practice of the population. (shrink)

1. A. Heyting (1930) introduced an intermediate logic whose semantics is based on a pair of states (‘here’ and ‘there’). This logic was axiomatized by Hosoi (1966), using the sequence of intermedia...

Information asymmetries are regarded as the main obstacle for consumers to buy responsibly. CSR labels are considered the best tool to give consumers information about the brand's social and environmental performance. Yet, the information and credibility gap associated to the labels may render labels useless. This study aims to unveil the relationship of Spanish consumers with CSR labels, in order to assess the posited consequences of the information and credibility gap. To do so, 385 consumers were interviewed at the main (...) shopping centers in Madrid. The findings support the hypothesized gaps, which leads to recommend public policies in order to improve the effectiveness of CSR labels as an information tool. (shrink)

One of the key questions in the contemporary analytic ontology concerns the relation between the Principle of Identity of Indiscernibles (PII) and the Bundle Theory (BT). The majority of authors believe that BT implies PII. Therefore, it is widely believed that the world violating PII presented by Max Black (1952. “The Identity of Indiscernibles.” Mind 61 (242): 153–64) is also devastating for BT. However, this has been questioned by Rodriguez-Pereyra (2004. “The Bundle Theory is Compatible with Distinct but Indiscernible Particulars.” (...) Analysis 64 (1): 72–81), who formulated an interpretation of BT with instances. Recently Robert (2019. “Can the Realist Bundle Theory Account for the Numerical Difference between Qualitavely Non-discernible Concrete Particulars?” Theorema 38 (1): 25–39) argued that this version of BT is not a constituent ontology and, therefore, Rodriguez-Pereyra’s solution comes at a price of excluding bundle theory from the domain of constituent ontologies, and, in this sense, it fails. I question Robert’s point by claiming that his account of constituent ontologies is too demanding. In particular, I show that the instance version of BT is compatible with the constrains defining constituent ontologies in general, and therefore Rodriguez-Pereyra’s argument is correct. (shrink)

A common strategy in comparative cognition is to require that one reject associative learning as an explanation for behavior before concluding that an organism is capable of causal reasoning. In this paper, I argue that standard causal-reasoning tasks can be explained by a powerful form of associative learning: unlimited associative learning (UAL). The lesson, however, is not that researchers should conduct more studies to reject UAL, but that they should instead focus on 1) enriching the cognitive hypothesis space and 2) (...) testing a broader range of information processing patterns—errors, biases and limits, rather than successful problem solving alone. (shrink)

Das Thema "Nietzsche und die Romantik" stellt eine unerschöpfliche Forschungsquelle und dabei ein mehrdimensionales, hermeneutisches Problem in der Literatur- und Philosophiegeschichte dar. Als erster nahm Karl Joël in seiner 1905 erschienenen Monographie "Nietzsche und die Romantik" die Frage der geistigen Verwandtschaft Nietzsches mit romantischen Autoren und der Verwurzelung seiner Philosophie in dem romantischen Komplex unter die Lupe. Aufschlussreiche Forschungsergebnisse lieferten darüber hinaus die Arbeiten von Ernst Behler, Linda Duncan, Ingrid Hennemann Barale, Steffen Dietzsch, Norbert Langer und Dirk von Petersdorff. Insgesamt (...) gehen die Meinungen der Forscher über Nietzsches Verhältnis zur Romantik auseinander. Die einen lehnen entschieden die These, Nietzsche sei der Fortsetzer der romantischen Linie, ab. Die anderen dagegen betonen die weltanschaulichen Ähnlichkeiten in der Denkweise des deutschen Philosophen und der Jenaer Romantiker und halten Nietzsche für den wichtigsten Entdecker der romantischen Motive. Es unterliegt keinem Zweifel, dass Nietzsches Beziehung zur Romantik durch Ambivalenz gekennzeichnet ist. Man muss aber in seinem Falle zwischen den verschiedenen Gestalten und Phasen der Romantik unterscheiden. Mit Sicherheit tritt er gegen die Romantik als die schmerzen- und leidensmildernde Erscheinung auf, die mit "Hunger" und nicht "Überfluss" zu assoziieren ist. Die romantische Kunst als "stimulans des Lebens" wird dann der dionysischen gegenübergestellt, die das Leben bejaht und das Tragische am Leben erscheinen lässt. Die negative Einschätzung der Romantik verbindet sich hier vor allem mit der Kritik an Wagner und Schopenhauer, also den absoluten Meistern aus der Frühphase im Schaffen Nietzsches. Einen anderen Bezugspunkt bietet aber die unterschwellige, geistige Verwandtschaft Nietzsches mit den Schöpfern der Frühromantik, worauf bereits Ernst Behler hingewiesen hat. Die Periodisierung und Differenzierung der Romantik lag zu Lebzeiten Nietzsches nicht vor. Es bleibt auch eine offene Frage, inwieweit der Autor des "Zarathustra" mit den Werken der Jenaer Romantiker vertraut war. Seine Novalis-Lektüre ist zwar dokumentiert, die ästhetischen Vorlesungen von August Wilhelm Schlegel sollen ihm bekannt gewesen sein, aber die eventuelle Friedrich-Schlegel-Lektüre kann durchaus in Frage gestellt werden. Empirische Befunde können somit nicht als ein Ausgangspunkt für die Bearbeitung der Parallelen im Werk Nietzsches und der Jenaer Romantiker dienen. Den Schwerpunkt soll man auf die geistig verwandte ästhetische Weltwahrnehmung und die aktive Form des Denkens legen, das von der widersprüchlichen Struktur des Seins ausgeht. Die Hauptidee gründet sich auf die zerstörerisch-schöpferische, und dadurch ironische, Konzeption des Lebens, die an das Postulat der Poetisierung und Revolutionisierung der Welt, das in-Frage-stellen der Wahrheit und die dynamische, perspektivistische Weltauffassung gebunden ist. Zu den wichtigsten Begriffen der frühromantischen Ästhetik gehören: Poesie, Ironie, Witz, Humor, Fantasie; Nietzsche führt die Kategorie der Kunst, des Dionysischen, des Tragischen und des Übermenschen ein. In beiden Fällen handelt es sich um die Überzeugung, dass die Welt sich ständig in Bewegung, im Prozess des Schaffens befindet. Friedrich Nietzsche gehört zu der sogenannten ironischen Literatur, die Frühromantiker angefangen haben und die im 20. Jahrhundert von solchen Schriftstellern wie Thomas Mann, Walter Benjamin oder Ernst Jünger fortgesetzt wird. (shrink)

Aquest treball explora la concepció de l'anàlisi de Moore tot relacionant-la amb la sevadefensa del sentit comú i el llenguatge ordinari com el seu vehicle d'expressió. La secció 1 estudiael paper que l'anàlisi representa en la seva filosofia, així com la seva importància perafrontar problemes filosòfics. La secció 2 descriu en què consisteix l'anàlisi segons Moore, discuteixels criteris que ha de satisfer una anàlisi correcta, i classifica els diferents tipus d'anà-lisi trobats en els escrits de Moore, alhora que nega que (...) se'ls pugui considerar lingüístics oconceptuals. La secció 3 aclareix les nocions de sentit comú i llenguatge ordinari, subratllantla preeminència d'aquell. La discussió es proposa de resoldre dues qüestions: a ) c o mes pot reconèixer una proposició del sentit comú, i b ) com es pot reconèixer si tal proposicióés vertadera. Finalment, ens concentrem en el paper concedit al sentit comú i/o llenguatgeordinari com a pedra de toc a l'hora d'acceptar o rebutjar arguments filosòfics. (shrink)

We examined spontaneous external offloading in a study requiring participants to plan the shortest route to connect locations on maps while satisfying ordering constraints. We manipulated map difficulty (low/high) and the possibility for participants to offload cognition by allowing/not allowing them to use a pen during planning (offloading/no offloading). Participants used more types of offloading strategies in the high (vs. low) difficulty maps and showed a better performance in the offloading (vs. no offloading) condition in the high difficulty maps only. (...) However, even in the low difficulty maps, cognition was offloaded, especially when participants solved the high difficulty maps first (perseveration effect). The use of offloading strategies and offloading-supported planning performance were positively related with visual search ability, while performance in the no offloading condition was positively related with spatial working memory. Findings show that offloading strategies are spontaneously deployed in a partly adaptive way in route planning on maps. (shrink)

Everyday Aesthetics, radicalizing Dewey’s notion of the continuity between art and experience, aims to find aesthetic qualities in ordinary experience. The problem is that it reduces the aesthetic significance that Dewey attributed to artistic production. Analyzing Dewey’s work and its interpreters, I will demonstrate that the continuity of ordinary experience and art is what lends art its vital and distinctive character. The work of art contributes to developing other ways of seeing and acting in the world, reinforcing life in common, (...) the basis of democracy. (shrink)

Este trabalho objetiva tecer reflexões acerca dos efeitos da proposta de Luis Alberto Warat de projetar no campo do Direito os aportes da Teoria da Carnavalização literária de Mikhail Bakhtin e da constituição do que ele denominou Epistemologia Carnavalizada. A partir das diversas linhas abertas pela sua obra A ciência jurídica e seus dois maridos, atravessada pelos conceitos bakhtinianos de carnaval, carnavalização, polifonia, dialogia e polissemia, intenta-se construir uma genealogia intermitente que coloca a própria obra como autêntico ato de carnavalização (...) do Direito. Isso se dá pelo efeito desestabilizador independente do alcance teórico da sua proposta da Epistemologia Carnavalizada. (shrink)

Harnecker, M. Política y clases sociales en Poulantzas (estudio crítico) -- Poulantzas, N. Sobre el concepto de política.

Within last twenty years in the European Union much regulation concerning advertisements of drugs changed. The aggressive marketing operations of producers of medicines caused that new solutions, not only legal but also ethical, had appeared. The European Union is imposing reliable solutions upon its members in the form of directives to which they must adapt their law. They can however decide to choose stricter law than the one which is recommended to them. The European Federation of Pharmaceutical Industry and Associations (...) – voluntary organization consisting associations of pharmaceutical companies from lots of countries is acting on similar principles. Each of the members belonging to it can implement its own, more restrictive regulation in the national ethical code than a Federation is ordering. Main purpose of this article is reading what legal and ethical solutions of pharmaceutical marketing were accepted in selected countries of the European Union. Whether they are stricter than the ones imposed upon them by European Union? How in this background Polish regulations are looking like? In the article also examples of the law-breaking and ethical principles by producers of medicines in the European Union will be presented. It will show sanctions taken out towards them for this reason. A question will be put: are various penalties able effectively to scare the pharmaceutical industry off the unethical or even unlawful advertising? (shrink)

In this paper, I analyze two methods of reading archives: ‘against the grain’ and ‘along the grain’. First one focuses mainly on revealing what is marginalized and omitted in archive’s dominant narration. The other carefully studies the logic of an archive itself. As such, reading against the grain allows to reveal victims’ forgotten stories, while reading along the grain helps to understand perpetrators’ perspective that may further lead to better recognition of the mechanisms of organized violence. I apply both approaches (...) to the album War against War (1924) by Ernst Friedrich, which contains archival photographs from World War I. Keywords: War against War; World War I; archival photographs; reading against the grain; reading along the grain. (shrink)

Can we speak of a feminine approach to caring for the body? If there is such an approach, how does culture influence or even construct it? Do we need a new culture of care in the medical field? Wha...

Thoughtprints Anne E. Berger andMarta Segarra I admit to it in the name of autobiography and in order to confide in you the following: [...] I have a particularly animalist perception and interpretation of what I do, think, write, live, ...

This study focuses on the application of multicriteria decision-making techniques, specifically the analytic hierarchy process (AHP), to identify corporate socialresponsibility information which both companies and stakeholders consider relevant and material. This work explains how the AHP methodology was applied in the selection of material indicators in corporate social responsibility reporting, the interpretation of these indicators and their relative importance. The results of this study are summarized in 60 indicators distributed in four areas: environment, economy, corporate governance and social. As this (...) last area contains the greatest number of indicators, it was divided into four sub-areas (human resources, human rights, product responsibility and society). (shrink)

Ce volume envisage l'amour en tant qu'objet polymorphe : Eros, Philia, Agapé, mais aussi Storgé. Les mots grecs rendent compte, du large spectre amoureux : amour romantique, amour sexuel, amour de soi, de l'autre, pour l'autre... des catégories qui placent les manifestations du sentiment amoureux dans un espace de contraintes et de possibilités qui relève du social et du discursif. Les travaux qui sont ici réunis s'attachent ainsi à interroger des genres artistiques et discursifs dans lesquels s'ancre l'amour, ils abordent (...) la littérature et le cinéma, mais aussi l'histoire, l'histoire des idées, la sociologie l'ethnologie ou la psychologie. Ces recherches mettent en avant que l'amour constitue une manière d'appréhender et d'expliquer le monde puisqu'on peut lire à travers lui les rapports qui définissent nos sociétés et qui le définissent à leur tour. (shrink)

Existem muitas teorias sobre democracia. Na verdade, enquanto se fala de “teoria democrática” como se existisse um consenso acerca do que esta poderia significar, a partir do momento em que nos debruçamos sobre diferentes autores, apercebemo-nos de que há tantas teorias quanto há perspectivas sobre o tema. Neste artigo tenho como interlocutores Robert Dahl, Benjamin Barber, Robert Goodin e David Plotke. O artigo tem três momentos. No primeiro, desenho o contexto geral para uma reflexão crítica sobre democracia, partindo da análise (...) dos seus conceitos constitutivos, nomeadamente, os conceitos de representação, participação e deliberação. Este é o momento “estrutural”. De seguida, apoiando-me nos critérios ou virtudes de Dahl e no conceito de “democracia forte” de Barber, defendo que a instanciação dos vários modelos democráticos depende da importância que se confere a cada um dos critérios. Este é o momento de conteúdo. Dialogando com estes autores procuro identificar as implicações dos modelos representativo, participativo e deliberativo. Por último, procuro uma forma de redefinição da democracia mais positiva para o futuro, tendo o orçamento participativo como prática exemplar a seguir. (shrink)

Cis‐regulatory elements govern gene expression programs to determine cell identity during development. Recently, the possibility that multiple enhancers are orchestrated in clusters of enhancers has been suggested. How these elements are arranged in the 3D space to control the activation of a specific promoter remains unclear. Our recent work revealed that the TGFβ pathway drives the assembly of enhancer clusters and precise gene activation during neurogenesis. We discovered that the TGFβ pathway coactivator JMJD3 was essential in maintaining these structures in (...) the 3D space. To do that, JMJD3 required an intrinsically disordered region involved in forming phase‐separated biomolecular condensates found in the enhancer clusters. Our data support the existence of a relationship between 3D‐conformation of the chromatin, biomolecular condensates, and TGFβ‐driven response during mammalian neurogenesis. In this review, we discuss how signaling (TGFβ), epigenetics (JMJD3), and biochemical properties (biomolecular condensates nucleation) are coordinated to modulate the genome structure to guarantee proper neural development. Moreover, we comment on the potential underlying mechanisms and implications of the enhancer‐mediated regulation. Finally, we point out the knowledge gaps that still need to be addressed. (shrink)