The Diagnosis Confirmation Model includes a dual-pricing mechanism designed to support value-based pricing of novel antibiotics while improving the alignment of financial incentives with their optimal use in patients at high risk of drug-resistant infections. DCM is a market-based model and complementary to delinked models. Policymakers interested in stimulating antibiotic innovation could consider tailoring the DCM to their reimbursement systems and incorporating it into the suite of incentives to improve the economics of antibiotics.

In this paper I provide support for the view that at least some forms of adversariality in argumentation are legitimate. The support comes from Aristotle’s theory of illegitimate adversarial argumentation in dialectical contexts: his theory of eristic in his work On Sophistical Refutations. Here Aristotle develops non-epistemic standards for evaluating the legitimacy of dialectical procedures, standards which I propose can be understood in terms of the pragmatic notion of context as common ground. Put briefly, Aristotle makes the answerer’s meaning in (...) giving assent in dialectical contexts the basis for further moves in the game of dialectic. Moves which subvert the answerer’s meaning or do not solicit the answerer’s consent are marked as eristic, i.e. adversarial in a problematic sense. I conclude with remarks on what Aristotle’s theory may teach us about how semantic features relate to the normative evaluation of argumentation. (shrink)

This article suggests that due to the value-laden nature of social issues, managerial values, as a framework or schema, play an important role in the social issues evaluation process. Our data show that there is clearly a relationship between the issues managers evaluate as important and the values of those managers, with values being defined according to the Carroll typology—economic, legal, ethical, and philanthropic. It was apparent that the values held by the managers sampled determined how various sets of issues—community, (...) political, and regulatory—were evaluated in terms of importance. This result suggests that the issues evaluation process, which should be objective, is not. (shrink)

This essay explores two strategies of inquiryin ecological science. Ecologists may regardthe sites they study either as contingentcollections of plants and animals, therelations of which are place-specific andidiosyncratic, or as structured systems andcommunites that are governed by general rules,forces, or principles. Ecologists who take thefirst approach rely on observation, induction,and experiment – a case-study or historicalmethod – to determine the causes of particularevents. Ecologists who take the secondapproach, seeking to explain by inferringevents from general patterns or principles,confront four conceptual obstacles (...) which thisessay describes. Theory in ecology must (1)define and classify the object it studies,e.g., the ecosystem, and thus determine theconditions under which it remains the ``same''system through time and change. Ecologistsmust (2) find ways to reject as well as tocreate mathematical models of the ecosystem,possibly by (3) identifying efficient causes ofecosystem organization or design. Finally,ecologists will (4) show ecological theory canhelp solve environmental problems both inpristine and in human-dominated systems. Afailure to solve – or even to address – theseobstacles suggests that theoretical ecology maybecome a formal science that studies themathematical consequences of assumptionswithout regard to the relation of theseassumptions to the world. (shrink)

This study investigates how dispute-mediators handle impasse in the re-negotiation of divorce decrees by divorced couples. Three sources of impasse and three strategies for handling impasse are identified based on analysis of mediation transcripts. The concern here lies not so much in the disputant's arguments but in the discussion procedures dispute-mediators use to craft the disputant's argumentation into a tool to solve conflict. Their moves are understood here as a practice of reconstructing argumentative discourse that is neither naïve nor critical (...) but reconstruction as design. Mediator's reconstruction reveals a type of communication work in contemporary societies involved in the crafting of forums and formats that mediate argumentative communication. This work is often invisible and strategic which makes its interpretation, judgment, and development a challenge for pragma-dialectical theory. How reconstruction as design can be understood is discussed by building on prior pragma-dialectical theory and research. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Plato’s CratylusRosamond Kent SpragueDavid Sedley. Plato’s Cratylus. New York: Cambridge University Press, 2003. Pp. xi + 190. Cloth, $60.00Discussion of Plato's Cratylus, to which this book is a notable contribution, must straightway come to terms with the question of Plato's seriousness (or lack thereof) in the etymology sections of the dialogue. Professor Sedley is a strong advocate of the seriousness of the etymologies, a position which, he remarks, (...) will not surprise most classicists, although it "may cause apoplexy among many of Plato's philosophical admirers" (23). More colloquially he writes, "if Plato was joking, the joke flopped" (39).But need we assume that Plato was either serious or joking? His sense of humor was peculiar, and seems to me nicely characterized by Guthrie when, in commenting on the present dialogue, he speaks of Plato as "tumbling together with an equally straight face absurdities and deeply held convictions" (History V, 25). I also incline more than Sedley to the frequent topicality of Plato's work.Nevertheless, the Sedley thesis may be seen to pay rich rewards. Perhaps most notable is the perception that the etymologies constitute a philosophical curriculum, moving along a well-defined trace from cosmology to the consideration (a watershed here) of ethical terms. This progression is especially significant in marking the emancipation of Plato from his early association with Cratylus and his subsequent allegiance to Socrates.Another mandatory topic is, of course, chronology. The Cratylus is seen to be unusual here in that what we have is most probably a reedited version. (A substantive point is at issue because the earlier version fails to distinguish clearly between the lawmaker and the [End Page 490] dialectician.) Thus to the question, where does the Cratylus fit in the traditional chronology, Sedley's answer is, "not in any one place" (7). As to the projected time of the revision, proximity to the Sophist is most likely.Sedley's general approach to the etymologies is hierarchical (here he identifies two important principles, Uniformity and Groundedness) rather than one of mutual support. He writes that the "'imitation' relation between sounds and things will be found [at] not just the primary level, but all the way up the chain" (126). Similarly with Socrates' painting analogy: "the primary pigments which the painter uses already imitate the simplest objects of vision" (128). In both cases the principles of Uniformity and Groundedness "are to some extent permitted to merge" (127).The business of name-making is of course a techne, as is that of painting. That both of these arts are approximate in nature is not an "ad hoc postulate [but] lies at the heart of Platonic metaphysics," since "any craftsman's embodiment of a Form in matter is necessarily less than perfect" (45). (As Sedley tellingly points out, "it is the Sophist Thrasymachus, and not Socrates, who proposes that a craftsman, qua craftsman, never gets anything wrong" [44].) As for Socrates' final position, it is "not the reversion to conventionalism that it has so often been taken to be" (145). Convention does play some part in signification, but it is also the case that names are some kind of vocal imitations, "a thesis, massively documented in the etymological section, from which Socrates never retreats" (145).One point on which I would like to have had Sedley's comments is the following: what does he think of Diogenes Laertius's remark (III, 6) that not only did Plato, after the death of Socrates, "attach himself to Cratylus the Heraclitean," but also to Hermogenes "who professed the philosophy of Parmenides"? Now the only real Parmenideanism in the dialogue (the position that a name is either a true name or not a name at all) is attributed not to Hermogenes but to Cratylus! (Is Descartes an empiricist? Is Hume a rationalist?) Furthermore, even though Cratylus adopts this position on a variety of occasions (429d, 432a, 433c, 436c, and 438c), he is too flighty (or, one might say, too fluxy) to stick with it, and continually relapses (431a, 432d, 433b, 435e, for instance). At the risk of being categorized as a non-serious reader of the Cratylus (which I am not... (shrink)

This book . . . is an invitation to all Christians to begin constructing a food ethics; to the academic Christian ethicist, it presents an opportunity to join a discussion on a topic relevant in so many ways to the life of every American; to the Christian for whom the spark of the divine is detectable in the everyday life, it is a chance to begin making ethical sense out of something done every day for the entirety of one's natural (...) life-participating in agriculture. -from the Introduction In Sustainable Agriculture, Mark Graham joins the vibrant, substantive discussion about the moral issues in American agriculture by revealing what is going on in current agricultural practices and analyzing them in light of morality and sustainability. Graham's constructive proposal for change is based on a moral vision that identifies a group of core values around which our agricultural system should be developed, including: a) a consistent, safe food supply; b) vital, sustainable communities; and c) personal and environmental health. (shrink)

Most recent discussions of phenomenal consciousness are predicated on two deeply entrenched assumptions. The first is objectualism, the claim that what it is like to undergo an experience is something of which we are or can be aware in the having of that experience. The second is internalism, the claim that what it is like to undergo an experience is constituted by states, events and processes that are located inside the skins of experiencing subjects. This paper argues that both assumptions (...) should be rejected. What it is like to undergo an experience is not an object of consciousness but something that exists in the directing of consciousness towards objects. What it is like to undergo an experience is not something of which we are aware, but something in virtue of which we are aware. And there is little reason for supposing that the directing of consciousness towards its objects is something that occurs exclusively inside the skins of experiencing subjects. On the contrary, directing of consciousness towards its objects is often extended, involving acts of worldly probing and exploration. (shrink)

In his essay, “Affording our Culture: “Smart” Technology and the Prospects for Creative Democracy,” Tibor Solymosi addresses my challenge for neuropragmatism to counter what I have elsewhere called dopamine democracy. Although I believe that Solymosi has begun to provide an explanation for how neuropragmatism may counter dopamine democracy, especially with his conceptions Œ and cultural affordances, I respond with a helpful addition to his approach by returning to the theory of inquiry as put forth by John Dewey. In particular, I (...) focus on the phases of inquiry as colored by Dewey’s concept of humility. Solymosi does not pay adequate attention to the function of inquiry necessary for combatting dopamine democracy. His account of cultural affordances and education is strengthened by using Dewey’s concept of humility as a guiding disposition for neuropragmatic inquiry. Recognizing humility as an instrument of neuropragmatic inquiry provides us with a tool to better address the pitfalls of dopamine democracy, especially misinformation and incentive salience. My argument proceeds by first articulating dopamine democracy as a problem and Solymosi’s concept of cultural affordances and how he understands these as neuropragmatic tools to address the problem through education. I present humility as an instrumental concept derived from Dewey’s work on inquiry. I then suggest how humility may serve neuropragmatic inquiry to assist in combatting the problems of dopamine democracy. (shrink)

For forty years, Harvey Mansfield has been worth reading. Whether plumbing the depths of MachiavelliOs Discourses or explaining what was at stake in Bill ClintonOs impeachment, MansfieldOs work in political philosophy and political science has set the standard. In Educating the Prince, twenty-one of his students, themselves distinguished scholars, try to live up to that standard. Their essays offer penetrating analyses of Machiavellianism, liberalism, and America., all of them informed by MansfieldOs own work. The volume also includes a bibliography of (...) MansfieldOs writings. (shrink)

Dynamically transforming the elements of any performing artist’s craft, this practical guide is a must-have for musicians, dancers, and actors. The handbook shows how artistic performance is embodied in the unification of three critical elements—motion, emotion, and love—demonstrating how it offers experiences and opportunities distinct from the nonperforming arts. Step-by-step guidelines are provided for building intentional and inspirational practice time, thereby enhancing the relationships between the source, the performer, and the audience. Illustrating how intentional movement invokes emotions from both the (...) performer and the audience and how the concept of love gives a performance humanity and life, this eye-opening exploration creates pathways for achieving true artistry. (shrink)

Every 4 years, for the past three decades, the world of argumentation research has gathered in Amsterdam at the International Society for the Study of Argumentation conferences to explore advances in understanding argumentation and how argumentation advances our understanding of the human condition. While comprehensive proceedings of selected papers are produced to document what has transpired in the world of argumentation over the preceding 4 years, there remains the important matter of taking the intellectual pulse of the world’s argumentation scholars, (...) to detect the beating heart of the community of scholars and the health and wellness of argumentation scholarship. One of the great services Frans van Eemeren, and his colleagues, have provided this community is a diagnosis that helps identify the assets upon which the health and wellness of the community can further build. This service has come in the form of several edited volumes, the most recent of which, Topical Themes in Argumen .. (shrink)

This volume offers selected papers exploring issues arising from scientific discovery in the social sciences. It features a range of disciplines including behavioural sciences, computer science, finance, and statistics with an emphasis on philosophy. The first of the three parts examines methods of social scientific discovery. Chapters investigate the nature of causal analysis, philosophical issues around scale development in behavioural science research, imagination in social scientific practice, and relationships between paradigms of inquiry and scientific fraud. The next part considers the (...) practice of social science discovery. Chapters discuss the lack of genuine scientific discovery in finance where hypotheses concern the cheapness of securities, the logic of scientific discovery in macroeconomics, and the nature of that what discovery with the Solidarity movement as a case study. The final part covers formalising theories in social science. Chapters analyse the abstract model theory of institutions as a way of representing the structure of scientific theories, the semi-automatic generation of cognitive science theories, and computational process models in the social sciences. The volume offers a unique perspective on scientific discovery in the social sciences. It will engage scholars and students with a multidisciplinary interest in the philosophy of science and social science. (shrink)

In lines 35–8 Ovid compliments the poem's recipient Brutus on his skill as a forensic orator. The transmitted text is as follows:hostibus eueniat quam sis uiolentus in armissentire et linguae tela subire tuae,quae tibi tam tenui cura limantur ut omnesistius ingenium corporis esse negent.