In this paper we position ourselves against idealist presuppositions so frequent in the humanities and social sciences, and, particularly, in communication theory. We argue that a realist approach to the study of communication avoiding such implausible assumptions is not only possible, but has already been exemplified in proposals that take communication to be a phenomenon with a biological origin. We argue that this sort of perspective can account for the variety of communicative functions we encounter in human experience, including the (...) ones involving senses. (shrink)

Puzzles concerning attitude reports are at the origin of traditional theories of content. According to most of these theories, content has to involve some sort of conceptual entities, like senses, which determine reference. Conceptual views, however, have been challenged by direct reference theories and informational perspectives on content. In this paper we lay down the central elements of the more relevant strategies for solving cognitive puzzles. We then argue that the best solution available to those who maintain a view of (...) content as truth conditions is to abandon the idea that content is the only element of mental attitudes that can make a difference as to the truth value of attitude reports. We finally resort to means of recognition of objects as one obvious element that helps explain differences in attitudes. (shrink)

Las tecnologías genéticas están poniendo a disposición del ser humano posibilidades de intervención nunca antes imaginadas. La magnitud de las aplicaciones potenciales nos obliga a una reflexión rigurosa desde el campo de la bioética, en la que se analicen los retos a que nos enfrentamos. Una parte de esta reflexión se refiere a lo que la biotecnología puede afectar a los derechos humanos, de ahí que haya documentos internacionales que se refieran a esta cuestión. En la base de todos ellos (...) está una preocupación por la dignidad humana, una categoría que se utiliza como concepto ético fundamental para establecer controles y límites, pero que en pocas ocasiones se define y analiza en profundidad. El objetivo de este trabajo es abordar el problema de la dignidad como clave los derechos humanos, en la relación con la ingeniería genética. (shrink)

La extensiva proliferación de conflictos sociales de grupos que claman exclusión política, indiferencia institucional y menosprecio de sus formas de vida, evidencian la insuficiencia conceptual del fin de la historia del Hegel de Fukuyama. Estos sujetos colectivos no se perciben como parte de la unidad orgánica que es lo social, sino como fragmentos escindidos, carentes de relación con ella. Sugiero que es posible otorgar valor explicativo y ofrecer una solución normativa a esta fractura social mediante el concepto de reconocimiento desarrollado (...) por Hegel en su periodo jenense. Así, como actualización de este concepto, estos conflictos sociales pueden ser entendidos como luchas por el reconocimiento por alguna de sus dimensiones, afectiva, legal y/o social que les ha sido injustamente negada. (shrink)

Although empirical evidence may provide a much desired sense of certainty amidst a pandemic characterised by uncertainty, the vast gamut of available COVID-19 data, including misinformation, has instead increased confusion and distrust in authorities’ decisions. One key lesson we have been gradually learning from the COVID-19 pandemic is that the availability of empirical data and scientific evidence alone do not automatically lead to good decisions. Good decision-making in public health policy, this paper argues, does depend on the availability of reliable (...) data and rigorous analyses, but depends above all on sound ethical reasoning that ascribes value and normative judgement to empirical facts. (shrink)

Por meio de processos-crime, reflete-se sobre a organização racial/racista da sociedade no passado. O assassinato de Vicente Crioulo, no ano de 1848, funciona como o primeiro paradigma para que se entenda que o Estado representa apenas um dos canais para a subjugação de povos não-brancos aos brancos dominadores. Esta abordagem filia-se à micro-história, e procura ver a vida cotidiana de homens e mulheres negras, escolhendo três casos paradigmáticos, que caminham da tortura e morte de um homem negro à uma rebelião (...) de escravos contra o seu feitor. Trata-se de uma narrativa de dor, mas também de resistência à ordem escravocrata. (shrink)

Volume 20, Issue 7, July 2020, Page 212-214.

This commentary defines what shared yet differentiated ethical responsibilities to tackle antimicrobial resistance (AMR) mean, by introducing a threefold principled account of AMR global governance. It argues that the principles of solidarity, subsidiarity, and stewardship can be especially helpful for further justifying some of the universal, differentiated, and individual responsibilities that Van Katwyk et al propose. The upshot of my threefold principled account of AMR global governance is a less ambitious AMR treaty, one that can only justify (i) universal duties (...) of global coordination (as per the principle of solidarity); (ii) differentiated duties to local communities, which bear the primary AMR responsibilities (as per the principle of subsidiarity); and (iii) individualized duties for ensuring truthful, evidence-based, consistent, and timely shared accountable communication (as per the principle of stewardship). (shrink)

Emotion regulation is one of the major foci of study in the fields of emotion and emotional development. This article proposes that to properly study emotion regulation, one must consider not only an intrapersonal view of emotion, but a relational one as well. Defining properties of intrapersonal and relational approaches are spelled out, and implications drawn for how emotion regulation is conceptualized, how studies are designed, how findings are interpreted, and how generalizations are drawn. Most research to date has been (...) conducted from an intrapersonal perspective, and the shortcomings of this approach for understanding emotion regulation are highlighted. The article emphasizes major conceptual and methodological steps required for a fuller description of the process of emotion regulation. (shrink)

Una respuesta al debate metafilosófico sobre si hay o no unos criterios regulativos en filosofía cómo área de investigación lo ofrece la denominada filosofía sintética. Dentro de esta posición se propone una forma de abordar toda la filosofía y teorizar en base a diferentes criterios propuestos, que suelen ser generalmente: la claridad semántica, la coherencia interna, la coherencia externa con las ciencias y la fecundidad teórica con otros campos de estudio. Estos criterios de corte naturalista a su vez se (...) ofrecen como debatibles y ampliables a otros criterios. Se razonará la necesidad de demarcar la filosofía, y, poniendo el foco en su metodología, se argumentarán los previos criterios con tal de fomentar la filosofía sintética como marco general de trabajo filosófico riguroso. Esto excluye de la disciplina tanto aquello que no sea filosófico como aquello que intente emular la filosofía sin serlo en verdad, la pseudofilosofía. (shrink)

This paper examines the problem of dying alone in the context of no-visitors hospital policy during the COVID-19 pandemic. It critically analyses a rights-based solution, offering a democratized vi...

Presentamos algunas ideas de autores medievales acerca de las oraciones cuyo sujeto carece de referente, y si dichas oraciones. Los autores tratados son nominalistas del siglo xiv: Guillermo de Ockham, Alberto de Sajonia y Juan Buridan; y el realista moderado Vicente Ferrer. Luego abordamos a dos novohispanos, Alonso de la Veracruz y Tomás de Mercado, que están inmersos en la tradición medieval.

The recent alleged doping case of the figure skater Kamila Valieva at the Winter Olympic Games in Beijing 2022 dramatically raised the issue of the protection of minors in anti-doping policy. We firstly present the literature on doping in relation to minors. Secondly, we present WADA’s Protected Person (PP) concept and its implications. Thirdly, we analyse the WADA Code’s purpose and the vulnerability of minors under the Code, and fourthly, we identify the real threats from which minors should be protected (...) by analysing the ineffective PP concept, and showing how it cannot be a real protection. We explain how preventing one threat can generate another, thus converting minor athletes from victims into suspects. We conclude by stressing the necessity for further research, and we indicate our future research direction, towards the development of a much wider concept of protection, and its application into sporting contexts. (shrink)

Resumen: Este texto es una respuesta abierta a las apreciaciones planteadas por las profesoras María Ávila Bravo-Villasante y Lydia de Tienda Palop, y los profesores Carlos Jesús Fernández Rodríguez y David Muñoz Rodríguez a la obra Mujeres y discursos gerenciales. Hacia la autogestión feminista. A lo largo de las presentes páginas se busca articular un diálogo entre miradas procedentes de diferentes disciplinas que contribuya a enriquecer la reflexión elaborada en dicha obra y abrir nuevos interrogantes sobre la misma. A (...) su vez, dicho diálogo permitirá seguir ampliando el campo de los estudios del management desde la perspectiva feminista.: This is an open response to the comments of professors María Ávila Bravo-Villasante, Lydia de Tienda Palop, Carlos Jesús Fernández Rodríguez, and David Muñoz Rodríguez to the book Mujeres y discursos gerenciales. Hacia la autogestión feminista. The aim is to articulate a dialogue among views from different disciplines that can contribute to enrich the reflection elaborated in the book and to open new questions about it, with the hope that this dialogue will help to expand the field of management studies from a feminist perspective. Palabras clave: postfeminismo, mujeres, liderazgo, gestión. Keywords: postfeminism, women, leadership, management. (shrink)

This paper develops a future-oriented and person-centred normative argument based on expectancies that is immune to most of the problems identified in the rights of future persons. The argument unfolds in four parts. The first draws on the notion of expectancies present in inheritance law and maintains that it is possible to formulate a rule of prospective beneficiaries that correlates with entitlements and legitimate claims without necessarily acquiring the status of rights. The second extends expectancies to future persons and concludes (...) that the latter can be considered present holders of such currently binding entitlements. The third section raises the question of whether democracies are bound to a principle of fidelity towards expectancies in such a way that outweighs current people’s rights in cases of conflicts. The response does not prove particularly future-beneficial in such cases. However, section four clarifies why expectancies still carry a crucial moral weight in democracies, one that is not sufficiently established by depersonalised forms of future-oriented ethics. (shrink)

Mostraremos como o Fedro de Platão é um terreno atípico, cujo léxico e alguns conceitos são flutuantes dentro do próprio diálogo, dificultando comparações lexicais com outros diálogos. Nosso ensaio mostrará a flutuação e a inversão de valores desse léxico-conceitual no próprio Fedro, tomando como exemplo quatro termos chave: doxa, razão, Eros e retórica. Consideraremos o caráter metodológico e epistemológico que a comparação lexical entre diálogos implica, tomando o Fedro como exemplo cujo bordado, comparado aos demais diálogos, sempre parece às avessas. (...) Assim, como as experientes bordadeiras, realizaremos avaliação desses termos não apenas pela figura manifesta, mas especialmente pelo seu avesso, cujo entrelaço deve ser tão ou mais belo que o lado externo. Palavras-chave: Fedro; Doxa; Razão; Eros e Retórica. The reverse side of embroidery: doxa, reason, Eros, and rhetoric in the Phaedrus Abstract: We will show how Plato's Phaedrus is an atypical terrain, whose lexicon and some concepts are floating within the dialogue itself, making lexical comparisons with other dialogues difficult. Our essay will show the fluctuation and inversion of values of this lexical-conceptual in Phaedrus himself, taking as an example four key terms: doxa, reason, Eros and rhetoric. We will consider the methodological and epistemological character that the lexical comparison between dialogues implies, taking the Phaedrus as an example whose embroidery, compared to the other dialogues, always seems to be in reverse. Thus, like the experienced embroiderers, we will evaluate these terms not only by the manifest figure, but especially by its reverse side, whose interlacing must be as or more beautiful than the external side. Keywords: Phaedrus; Doxa; Reason; Eros and Rhetoric. El reverso del bordado: doxa, razón, Eros y retórica en el Fedro Resumen: Mostraremos cómo el Fedro de Platón es un terreno atípico, cuyo léxico y algunos conceptos flotan dentro del propio diálogo, dificultando las comparaciones léxicas con otros diálogos. Nuestro ensayo mostrará la fluctuación e inversión de valores de este léxico-conceptual en el propio Fedro, tomando como ejemplo cuatro términos clave: doxa, razón, Eros y retórica. Consideraremos el carácter metodológico y epistemológico que implica la comparación léxica entre diálogos, tomando como ejemplo el Fedro cuyo bordado, frente a los demás diálogos, parece siempre invertido. Así, como los bordadores experimentados, evaluaremos estos términos no sólo por la figura manifiesta, sino especialmente por su reverso, cuyo entrelazamiento debe ser tanto o más bello que el exterior. Palabras clave: Fedro; Doxa; Razón; Eros y Retórica. Data de registro: 02/08/2023 Data de aceite: 20/09/2023. (shrink)

In representative democracies, the absence of responsiveness by elected officials to the interests of the represented often generates problems of legitimacy, accountability and effectiveness. However, responsiveness also tends to narrow the time horizons of democratic decision-making and promote short-termism. This paper advances the notion that responsiveness to interests involving distant time horizons is possible by reconfiguring the franchise in a time-sensitive and future-oriented way. It is divided into two parts. The first pinpoints a few inconsistencies in the available proposals for (...) making responsiveness and the long term compatible (e.g., promoting youth turnout, narrowing the franchise to robust epistemic fitness, establishing future-oriented institutions). The second advances the creation of temporal electoral circles operating alongside territorial electoral circles in order to prompt responsiveness to multitemporal interests. The conclusion asserts that this kind of franchise design is the best available option for introducing temporal aspects into the character of democratic representation. (shrink)

Epistemic impairment has been the decisive yardstick when excluding infants from political agency. One of the suggestions to bypass the epistemic requirement of political agency and to encourage the inclusion of infants in representative democracies is to resort to proxies or surrogates who share or advocate interests which may be coincidental with their interests. However, this solution is far from desirable, given that it privileges the political agency of parents, guardians and trustees over other adult citizens. This article offers an (...) alternative to this conceptual frame of reference by making a case for the political agency of infants. Firstly, it maintains that political agency can be understood in terms of the several facets involved in political representation. Secondly, it claims that the all-affected principle can be reformulated as an ‘infant-affected-interests principle’ in light of which infants are members of the class of the represented. Thirdly, it explores the ways through which this political agency can occur without having to resort to alternative conceptions of representation. The conclusion ascertains that infant enfranchisement is highly undesirable and that there are more viable forms to promote infant political agency, such as virtual representation, infant-beneficial principles of political action and ombudspersons for infants. (shrink)

The moral value of health : health as a basic human need -- The human right to health and its corresponding responsibilities -- States and natural persons as subjects of justice -- Pharmaceutical transnational corporations as subjects of justice -- The global health governance of the global health crisis.

European Journal of Political Theory, Volume 21, Issue 2, Page 368-389, April 2022. Epistemic impairment has been the decisive yardstick when excluding infants from political agency. One of the suggestions to bypass the epistemic requirement of political agency and to encourage the inclusion of infants in representative democracies is to resort to proxies or surrogates who share or advocate interests which may be coincidental with their interests. However, this solution is far from desirable, given that it privileges the political agency (...) of parents, guardians and trustees over other adult citizens. This article offers an alternative to this conceptual frame of reference by making a case for the political agency of infants. Firstly, it maintains that political agency can be understood in terms of the several facets involved in political representation. Secondly, it claims that the all-affected principle can be reformulated as an ‘infant-affected-interests principle’ in light of which infants are members of the class of the represented. Thirdly, it explores the ways through which this political agency can occur without having to resort to alternative conceptions of representation. The conclusion ascertains that infant enfranchisement is highly undesirable and that there are more viable forms to promote infant political agency, such as virtual representation, infant-beneficial principles of political action and ombudspersons for infants. (shrink)

The book forms a balanced structure in which the three conceptual pillars of Spinoza's natural law theory (individuality, natural laws, and power) are first analyzed from the viewpoint of his ontology and then from the viewpoint of his ...

From the scene of the singing cicadas in the _Phaedrus_, we will show the affinities between the mention of the dangerous sleep at noon (_Phdr_. 258e6-259d8) and a mythical episode in the life of Epimenides. Next, we will look at the possible affinities between the description of Dionysian madness (_Phdr_. 244d5-245a1) and the type of divination practiced by Epimenides of Crete (DK 3 B 1-25). From these approaches, we intend to describe and elucidate the common imaginary with which Plato elaborates (...) his reception and assimilation of the archaic poetic tradition in his philosophy. (shrink)

This article challenges the orthodox view of international law, according to which states have no legal duty to cooperate. It argues for this legal duty in the context of COVID-19, based on the ethical principles of solidarity, stewardship, and subsidiarity. More specifically, the article argues that states have a legal duty to cooperate during a pandemic (as solidarity requires); and while this duty entails an extraterritorial responsibility to care for and assist other nations (as stewardship requires), the legal duty to (...) cooperate still allows states to attend first to the basic needs of those under their own jurisdiction—namely, fellow nationals and residents (as subsidiarity requires). The article provides a definition and philosophical justifications for this legal duty that are lacking in the literature by examining its application to a current COVID-19 controversy: namely, states’ responsibility to assist other countries in greater need by, inter alia, exporting at a discount or donating scarce COVID-19 treatments (including vaccines). In providing a principled tripartite account of pandemic governance, this conceptual and normative article offers a new lens for debating the potential international treaty for pandemic prevention, preparedness, and response that has now been drafted and is under negotiation at the World Health Assembly, by responding to the recent backlash against multilateralism by substantiating global co-responsibilities in times of pandemics and beyond. (shrink)

This paper has two main goals: first, to circumscribe the topic in Merleau-Ponty’s work, focusing especially on his first book, and second, to delimit the question in The Structure of Behavior itself, focusing especially on his description of the perceptual dimension of structure.

This study argues against the expansive approach to the WHO reform, according to which to be a better global health leader, WHO should do more, be given more power and financial resources, have more operational capacities, and have more teeth by introducing more coercive monitoring and compliance mechanisms to its IHR. The expansive approach is a political problem, whose root cause lies in ethics: WHO’s political overambition is grounded on WHO’s lack of conceptual clarity on what good leadership means and (...) what health (as a human right) means. This study presents this ethical analysis by putting forth an alternative: the humble approach to the WHO reform. It argues that to be a better leader, WHO should do much less and have a much narrower mandate. More specifically, WHO should focus exclusively on coordination efforts, by ensuring truthful, evidence-based, consistent, and timely shared communications regarding PHEIC among WHO member-states and other global health stakeholders, if the organization desires to be a real global health leader whose authority the international community respects and whose guidance people trust. (shrink)

: C.S. Peirce defines mathematics in two ways: first as "the science which draws necessary conclusions," and second as "the study of what is true of hypothetical states of things" (CP 4.227–244). Given the dual definition, Peirce notes, a question arises: Should we exclude the work of poietic hypothesis-making from the domain of pure mathematical reasoning? (CP 4.238). This paper examines Peirce's answer to the question. Some commentators hold that for Peirce the framing of mathematical hypotheses requires poietic genius but (...) is not scientific work. I propose, to the contrary, that although Peirce occasionally seems to exclude the poietic creation of hypotheses altogether from pure mathematical reasoning, Peirce's position is rather that the creation of mathematical hypotheses is poietic, but it is not merely poietic, and accordingly, that hypothesis-framing is part of mathematical reasoning that involves an element of poiesis but is not merely poietic either. Scientific considerations also inhere in the process of hypothesis-making, without excluding the poietic element. In the end, I propose that hypothesis-making in mathematics stands between artistic and scientific poietic creativity with respect to imaginative freedom from logical and actual constraints upon reasoning. (shrink)

VIEIRA, José Álvaro Campos. Aurora de uma espiritualidade sem religião: análise dos sem religião a partir da concepção de espiritualidade não religiosa de Marià Corbi. 2014. Dissertação , Programa de Pós-graduação em Ciências da Religião, Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte.

in two letters concerning the Spanish-American War of 1898, Charles Sanders Peirce openly expresses some egregious prejudices against several groups of people, including Hispanics—people of at least partly Spanish origin in the Iberian Peninsula or the Americas (L 254 and L 339; reprint, translation to Spanish, and commentary in Nubiola and Zalamea 76–811). In an undated letter to his cousin Henry Cabot Lodge, a Massachusetts politician, Peirce writes regarding the war: “I don’t believe the Spaniards will make a good fight; (...) for as I have studied them in Spain, the whole people has been corrupted with the centuries of cruelty, injustice and rapine they have indulged in, and have little real manhood left” (L 254; .. (shrink)

En el siguiente trabajo exponemos la tesis de Emmanuel Levinas según la cual en la subjetividad se entrelazan dos momentos, uno ontológico y uno propiamente ético, alejándose así del paradigma de la identidad. Sostenemos que dicha estructura co-implicada de la subjetividad puede entenderse, a partir de las dos obras principales de Levinas, a la luz de un movimiento incorporativo no-asimilativo de la alteridad. Mostramos así, en primer lugar, cómo la retórica alimentaria del comer-al y con-otro no sólo puede tener rendimiento (...) especulativo en el caso de la tematización de la estructura ontológica del vivir de… sino que incluso funciona como catacresis fundamental en el caso de la exposición de la subjetividad como substitución. Finalmente, proponemos que estos análisis permiten una relectura de la estructura misma de la relación general con la alteridad en Levinas en términos de incorporación. In the following article we expose Emmanuel Levinas’ thesis about an altered subjectivity that has two intertwined moments: one ontological and one properly ethical. We hold that this co-implicated structure of subjectivity can be understood, in the context of the two main works of Levinas, in the light of a non-assimilative incorporative movement of alterity. We show, in the first place, how the rhetoric of eating the-other and with-other has an speculative function both in the thematization of the ontological structure of the living of... and in the thesis about subjectivity as a substitution – as a fundamental catachresis. Finally, we propose that these analyzes allow a rereading of the structure of the general relationship with otherness in Levinas in terms of incorporation. (shrink)

This article examines the relation between the dialectical program established in Plato’s Republic and the practice of dialectic in other dialogues, such as the Parmenides and the Theaetetus. The author argues against those scholars who have sustained a sharp distinction between an intuitive conception of knowledge and the discursive practices characteristic of Plato’s concept of dialectic. In his view, Plato has been overinterpreted from the modern perspective of the distinction between intuitive and discursive forms of knowledge. As a consequence, this (...) article also examines the relation between the dialectical practices displayed in the Parmenides and the Theaetetus and the anhypothetical condition that Plato attributes to “the principle of everything” in the Republic. (shrink)

Resumo: Por intermédio da análise dos gêneros carta e conto escritos por Machado de Assis, procuramos oferecer uma resposta à questão do horizonte ético e moral que opera nos textos do autor. Trabalhamos numa perspectiva interdisciplinar, pois dialogamos com filósofos, historiadores e críticos literários procurando, num primeiro momento, demonstrar que a noção de cuidado de si se mostra na correspondência machadiana a partir da perspectiva de cura de si, isto é, um tipo de sabedoria dos antigos gregos e romanos que (...) o autor lança mão para realizar e organizar o pensamento literário, seu e de seus pares, na direção das publicações e conquistas no âmbito da literatura. Num segundo momento, demonstramos que o cuidado de si terá outro sentido nos textos de ficção, pois se volta para um cuidado da alma no sentido do desenvolvimento do pensamento crítico do sujeito em relação ao eu e ao outro, ao indivíduo e ao mundo social. Palavras-chave: Machado de Assis; Cuidado de Si; Cartas; Literatura. The care of the self as an ethical perspective in Machado de Assis Abstract : Through the analysis of the genres letter and short story written by Machado de Assis, we try to offer an answer to the question of the ethical and moral horizon that operates in the author's texts. We work in an interdisciplinary perspective, as we dialogue with philosophers, historians and literary critics, trying, in a first moment, to demonstrate that the notion of self-care is shown in Machado's correspondence from the perspective of self-cure, that is, a kind of wisdom from the ancient Greeks and Romans that the author uses to accomplish and organize the literary thought, his own and his peers', in the direction of publications and achievements in the field of literature. In a second moment, we demonstrate that the care of the self will have another meaning in fiction texts, since it turns to a care of the soul in the sense of the development of the subject's critical thought in relation to the self and to the other, to the individual and to the social world. Keywords: Machado De Assis; Self-Care; Letters; Literature. Le souci de soi comme perspective éthique chez Machado de Assis Résumé : A travers l'analyse des genres lettre et nouvelle écrits par Machado de Assis, nous essayons d'offrir une réponse à la question de l'horizon éthique et moral qui opère dans les textes de l'auteur. Nous travaillons dans une perspective interdisciplinaire, car nous dialoguons avec des philosophes, des historiens et des critiques littéraires en essayant, dans un premier temps, de démontrer que la notion d'auto-soin apparaît dans la correspondance de Machado dans la perspective de l'auto-cure, c'est-à-dire une sorte de sagesse des anciens Grecs et Romains que l'auteur utilise pour accomplir et organiser la pensée littéraire, la sienne et celle de ses pairs, vers des publications et des conquêtes dans le domaine de la littérature. Dans un deuxième temps, nous démontrons que le souci de soi aura un autre sens dans les textes de fiction, car il se transforme en soin de l'âme au sens du développement de la pensée critique du sujet par rapport au moi et à l'autre, à l'individu et au monde social. Mots-Clés: Machado De Assis; Soins Personnels; Letres; Littérature. Data de registro: 22/11/2022 Data de aceite: 24/04/2023. (shrink)

The extent of neurogenesis in Drosophila is under the control of the so‐called neurogenic genes, named for their mutant phenotype of causing neural hyperplasia. Their wild‐type products appear to be responsible for a signal chain that decides the fate of ectodermal cells in the embryo. Various kinds of data, from cell transplantation experiments as well as from genetic and molecular analyses, suggest that the proteins encoded by the genes Notch and Delta may act at the membrane of the signal‐transmitting cells (...) to provide a ligand to a still unknown receptor molecule; in contrast, the locus of Enhancer of split codes for several functions related to the transduction and further processing of the signal. (shrink)

ABSTRACTA much debated passage in the Metaphysics of Morals often leads commentators to believe that it is not possible to act from juridical duty. On the one hand, Kant says that all lawgiving inc...

ABSTRACTOne of the recurrent motifs in political thought is the idea of the social contract, according to which a society, a government, or moral principles depend for their existence on agreements...

It is generally accepted that patents are a driving force for innovation through research and development. But the university's involvement in patenting is problematic as well. In particular, it is in tension with the idea of a university itself. If patents entail a restriction on the accessibility of the scientific knowledge that has been patented, and if the main purpose of universities is to produce and disseminate knowledge to the public, then, there is a tension: when universities patent their research (...) innovations, they are making the scientific knowledge they produce less accessible to the public. The paper argues that university patenting contradicts the very idea of a university as an institution whose mission is fundamentally to disseminate the knowledge it produces to the public. The practice of university patenting involves an un-academic attitude thus: by inciting an attitude towards knowledge that is not consistent with the proper attitudes and goals of a university, university patenting hurt.. (shrink)

Resumen: El siguiente artículo presenta la formulación del concepto identidad cultural regional, a partir de una selección del aspecto mental de la cultura, lo que dio como resultado una definición discursiva narrativa de identidad cultural regional. Para esto se presentan fundamentos metafísicos, lingüísticos e históricos, y una contextualización compuesta de definiciones de identidad cultural, identidad cultural latinoamericana e identidad cultural regional. Respecto de esta última, se presentan aplicaciones al estudio de la Identidad Cultural de la Región de los Ríos, debido (...) a las características de este territorio como nueva región. El concepto resultante describe el fenómeno como un sentido del ser regional presente en la semiosfera cultural, formando parte de la memoria y del imaginario colectivo, manifestado en el modo de la unidad temática de una narración histórica coherente y ordenada, progresivamente más compleja y heterogénea, que combina la progresión lineal de los subtemas y el tema constante de la identidad cultural regional.: The following article presents the formulation of the concept of regional cultural identity, based on a selection of the mental aspect of culture, which resulted in a narrative discursive definition. For this, metaphysical, linguistic and historical foundations are presented, and a contextualization composed of definitions of cultural identity, Latin American cultural identity and regional cultural identity. Regarding the latter, applications to the study of the Cultural Identity of the Region de los Rios are presented, due to the characteristics of this territory as a new region. The resulting concept describes the phenomenon as a sense of the regional being present in the cultural semiosphere, forming part of the collective memory and imaginary, manifested in the way of the thematic unity of a coherent and ordered historical narrative, progressively more complex and heterogeneous, which combines the linear progression of the subthemes and the constant theme of regional cultural identity. (shrink)

The main objective of this work is to discuss the materiality of relationships and experiences of infants in early childhood education, based on a dialogue with the Brazilian curriculum guidelines for Early Childhood Education in 3 municipalities in the state of São Paulo, and with the concepts of technical objects and individuation developed by Simondon. This is a qualitative research that uses bibliographic and documentary research as a methodology and the production of cartographies of scenes in which relationships between babies (...) and objects are observed. The cartography used here is inspired by the records developed by Fernand Deligny (2015) and its appropriation for research with babies, as proposed by Julia Oliveira (2016). Research was carried out on this topic in the field of education, going through scientific articles and guiding documents for early childhood education. The authors mapped the paths and affections of babies and their relationships with objects in two distinct scenes that were collected within the scope of a collective project. It is a work that contributes to early childhood education in general and, specifically, to baby studies (Infantology, Babyhood studies). (shrink)